A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Search for products or services, then visit the suppliers website for prices or more information.
| Product | Description | |
|---|---|---|
| Mirtazapine Impurity 16 | Mirtazapine Impurity 16. Uses: For analytical and research use. CAS No. 1188266-12-7. Molecular formula: C16H14D4ClN3. Mole weight: 291.82. Catalog: APB1188266127. |  |
| Mirtazapine Impurity 17 | Mirtazapine Impurity 17. Uses: For analytical and research use. CAS No. 1330264-96-4. Molecular formula: C17H16D3N3O. Mole weight: 284.38. Catalog: APB1330264964. | |
| Mirtazapine Impurity 3 | Mirtazapine Impurity 3. Uses: For analytical and research use. Molecular formula: C16H16N4O. Mole weight: 280.33. Catalog: APB11378. | |
| Mirtazapine Impurity 4 | Mirtazapine Impurity 4. Uses: For analytical and research use. CAS No. 1206793-47-6. Molecular formula: C17H19ClN4. Mole weight: 314.82. Catalog: APB1206793476. | |
| Mirtazapine Impurity 5 | Mirtazapine Impurity 5. Uses: For analytical and research use. CAS No. 1080533-15-8. Molecular formula: C23H28N3O6+. Mole weight: 442.49. Catalog: APB1080533158. | |
| Mirtazapine Impurity 6 | Mirtazapine Impurity 6. Uses: For analytical and research use. CAS No. 155172-12-6. Molecular formula: C17H19N3O. Mole weight: 281.36. Catalog: APB155172126. | |
| Mirtazapine Impurity 7 | Mirtazapine Impurity 7. Uses: For analytical and research use. CAS No. 61337-89-1. Molecular formula: C17H21N3O. Mole weight: 283.38. Catalog: APB61337891. | |
| Mirtazapine Impurity 8 | Mirtazapine Impurity 8. Uses: For analytical and research use. CAS No. 61338-13-4. Molecular formula: C17H19N3O2. Mole weight: 297.36. Catalog: APB61338134. | |
| Mirtazapine Impurity 9 | Mirtazapine Impurity 9. Uses: For analytical and research use. CAS No. 61337-68-6. Molecular formula: C16H17N3. Mole weight: 251.33. Catalog: APB61337686. | |
| Mirtazapine N-oxide | Mirtazapine N-oxide. Alternative Names: 1,2,3,4,10,14b-Hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 2-Oxide. CAS No. 155172-12-6. Purity: 96%. Product ID: ACM155172126. Molecular formula: C17H19N3O. Mole weight: 281.35. IUPAC Name: Mirtazapine-N-oxide. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Mirtazapine N-Oxide | A metabolite of Mirtazapine. Group: Biochemicals. Alternative Names: 1,2,3,4,10,14b-Hexahydro-2-methyl-pyrazino[2,1-a]pyrido[2,3-c][2]benzazepine 2-Oxide. Grades: Highly Purified. CAS No. 155172-12-6. Pack Sizes: 5mg. US Biological Life Sciences. |  Worldwide |
| Mirtazapine Related Compound A | Mirtazapine Related Compound A. Uses: For analytical and research use. CAS No. 61337-68-6. Mole weight: 251.33. Catalog: AP61337686-B. | |
| Mirtazapine Related Compound B | Mirtazapine Related Compound B. Uses: For analytical and research use. CAS No. 155172-12-6 (anhydrous). Mole weight: 299.37. Catalog: ALP155172126. | |
| Mirtazapine Related Compound C | Mirtazapine Related Compound C. Uses: For analytical and research use. CAS No. 191546-96-0. Mole weight: 279.34. Catalog: AP191546960. | |
| Mirtazapine Related Compound D | Mirtazapine Related Compound D. Uses: For analytical and research use. CAS No. 191546-97-1. Mole weight: 279.34. Catalog: AP191546971. | |
| Mirvetuximab | Mirvetuximab (M9346A) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: M9346A. CAS No. 1453084-36-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99225. |  |
| Mirvetuximab (powder) | Mirvetuximab (M9346A) (powder) is an anti-FOLR1 (folate receptor 1) monoclonal antibody. Mirvetuximab (powder) is the antibody moiety of folate receptor alpha (FRα)-targeting ADC (Mirvetuximab soravtansine). Mirvetuximab soravtansine can be used in ovarian and other FRα-positive cancer research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: M9346A (powder). CAS No. 1453084-36-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99225A. | |
| Mirvetuximab soravtansine (solution) | Mirvetuximab soravtansine (IMGN853) solution is an anti-folate receptor α (FRα) antibody drug-conjugate (ADC) consisting of the cytotoxic maytansinoid, DM4, covalently linked to the humanized monoclonal antibody M9346A, and the drug-linker conjugate for ADC is sulfo-SPDB-DM4 (HY-101141). Mirvetuximab soravtansine selectively binds to folate receptor 1 (FOLR1). Mirvetuximab soravtansine has an anti-proliferative effect via growth arrest and augmented DNA damage[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMGN853 (solution). CAS No. 1453084-37-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132258A. | |
| Mirzotamab | Mirzotamab is an IgG1κ monoclonal antibody targeting to CD276/B7-H3 with anti-tumor activity. Mirzotamab conjugates with Clezutoclax (HY-137774), a BCL inhibitor to form Mirzotamab clezutoclax (HY-P99741), involving in research with taxane research in relapsed/refractory solid tumors. Mirzotamab clezutoclax (ABBV-155) is a targeted antibody drug conjugate (ADC)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2229859-11-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99740. | |
| Misch Metal, 99.0% min. rare earth content | Misch Metal, 99.0% min. rare earth content. CAS No. 62379-61-7. Molecular formula: CeLaNdPr. Mole weight: 564.17g/mol. IUPAC Name: cerium;lanthanum;neodymium;praseodymium. SMILES: [La].[Ce].[Pr].[Nd]. InChI: InChI=1S/Ce.La.Nd.Pr. |  |
| Misch Metal, 99.8% min. rare earth content, trapezoidal ingot, dry | Misch Metal, 99.8% min. rare earth content, trapezoidal ingot, dry. CAS No. 62379-61-7. Molecular formula: CeLaNdPr. Mole weight: 564.17g/mol. IUPAC Name: cerium;lanthanum;neodymium;praseodymium. SMILES: [La].[Ce].[Pr].[Nd]. InChI: InChI=1S/Ce.La.Nd.Pr. | |
| Mischmetal-nickel alloy | Description General description We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product has been enhanced for energy efficiency. Find details here. Application Mischmetal-nickel alloy is a hydrogen storage alloy, which consists of rare earth metals and transition metals. It can be used as an anode material for the formation of nickel-metal hydride batteries. These batteries can further be utilized in hybrid vehicles. Packaging 10 g in glass bottle. CAS No. 54426-34-5. Molecular formula: (Ce,La,Nd,Pr)Ni5. InChI: 1S/Co.La.Ni. | |
| Misgurin | A novel antimicrobial peptide, named misgurin, was isolated and characterized from the loach (mudfish), Misgurnus anguillicaudatus. Misgurin showed a strong antimicrobial activity in vitro against a broad spectrum of microorganisms without significant hemolytic activity and was about 6 times more potent than magainin 2. Molecular formula: C106H189N41O29. Mole weight: 2501.88. |  |
| Misitatug | HY-P990929 is an MSLN-targeting IgG1κ type chimeric antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RC-88 Antibody. CAS No. 2767203-01-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990929. | |
| m-Isobutyl Ibuprofen | An Ibuprofen impurity used in the study of potent noncompetitive interleukin-8 inhibitors. Group: Biochemicals. Alternative Names: α -Methyl-3- (2-methylpropyl) benzeneacetic Acid, α - (3-Isobutylphenyl) propionic Acid; α -Methyl-3- (2-methylpropyl) phenylacetic Acid; 2- (3-Isobutylphenyl) propionic Acid. Grades: Highly Purified. CAS No. 66622-47-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Misoprostol | A cytoprotective prostaglandin PGE1 analogue. Group: Biochemicals. Alternative Names: (11α,13E)-(+/-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic Acid Methyl Ester; Cytotec; Misogon; Misoprostil; SC 29333. Grades: Highly Purified. CAS No. 59122-46-2. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Misoprostol, 1% in Cellulose | Misoprostol, 1% in Cellulose. Group: Biochemicals. Alternative Names: (11a,13E)-(+/-)-11,16-Dihydroxy-16-methyl-9-oxoprost-13-en-1-oic acid methyl ester; Cytotec; Misogon. Grades: Highly Purified. CAS No. 59122-46-2. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C22H38O5, Molecular Weight: 382.53. US Biological Life Sciences. | Worldwide |
| Misoprostol acid | Misoprostol acid is an active metabolite of Misoprostol. Misoprostol is a synthetic analogue of prostaglandin E1 (PGE1), extensively absorbed, and undergoes rapid de-esterification to Misoprostol acid in the gastrointestinal tract after oral administration. Misoprostol can be used for non-steroidal anti-inflammatory drug-induced (NSAID) gastric ulcers[1]. Misoprostol is an oral agent used to induce labor[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 112137-89-0. Pack Sizes: 1 mg (27.14 mM * 100 μL in Methyl acetate). Product ID: HY-118189. | |
| Misoprostol acid (10 mg in 1 mL methyl acetate) | Misoprostol acid (10 mg in 1 mL methyl acetate). Group: Biochemicals. Alternative Names: (11a,13E)-11,16-Dihydroxy-16-methyl-9-oxo-prost-13-en-1-oic acid; Misoprostol free acid; (+/-)-15-Deoxy-(16RS)-16-hydroxy-16-methylprogestaglandin E1. Grades: Highly Purified. CAS No. 112137-89-0. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C21H36O5. US Biological Life Sciences. | Worldwide |
| Misoprostol-d4 | Labelled Misoprostol, a cytoprotective prostaglandin PGE1 analogue. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Misoprostol EP Impurity A | Misoprostol EP Impurity A. Uses: For analytical and research use. CAS No. 1788085-78-8. Molecular formula: C22H38O5. Mole weight: 382.54. Catalog: APB1788085788. | |
| Misoprostol Impurity 1 | Misoprostol Impurity 1. Uses: For analytical and research use. Molecular formula: C22H38O5. Mole weight: 382.54. Catalog: APB12291. | |
| Misoprostol Impurity 2 | Misoprostol Impurity 2. Uses: For analytical and research use. CAS No. 58682-86-3. Molecular formula: C22H36O4. Mole weight: 364.53. Catalog: APB58682863. | |
| Mitapivat | Mitapivat (AG-348) is an orally active pyruvate kinase allosteric activator. Mitapivat increases enzymatic activity, protein stability, and ATP levels over a broad range of PKLR genotypes, shows the potential to restore the activity of PK (pyruvate kinase)-deficient glycolytic pathways. Mitapivat can be used in study of PK deficiency[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG-348. CAS No. 1260075-17-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-12689. | |
| Mitazalimab | Mitazalimab (ADC-1013; JNJ-64457107) is FcγR-dependent CD40 agonist with tumor-directed activity. Mitazalimab activates antigen-presenting cells, e.g. dendritic cells (DC), to initiate tumor-reactive T cells. Therefore, Mitazalimab induces tumor-specific T cells to infiltrate and kill tumors. Mitazalimab remodels the tumor-infiltrating myeloid microenvironment[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ADC-1013; JNJ-64457107; Vanalimab. CAS No. 2055640-86-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99742. | |
| Mithramycin | Mithramycin was the first of the aureolic acid class of antitumor antibiotics isolated from Streptomyces. Mithramycin inhibits transcription and protein synthesis by non-covalent binding with G-C-rich duplex DNA in the presence of magnesium and zinc ions. Mithramycin has also been shown to induce differentiation of leukemic cells accompanied by an early decrease in c-myc expression and selectively inhibit collagen-1 gene expression in human fibroblasts. Group: Biochemicals. Grades: Highly Purified. CAS No. 18378-89-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Mithramycin A | Mithramycin A is an antineoplastic antibiotic produced by Streptomyces plicatus. Mithramycin A is a polymerase inhibitor that binds to GC rich sequences located in the minor groove of DNA. Uses: Antibiotics, antineoplastic, fluorescent dyes, nucleic acid synthesis inhibitors, protein synthesis inhibitors. Synonyms: D-threo-2-Pentulose, 5-deoxy-1-C-[(2S,3S)-7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-lyxo-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-arabino-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-, (1S)-; [1S(2S,3S)]-5-Deoxy-1-C-[7-[[2,6-dideoxy-3-O-(2,6-dideoxy-β-D-arabino-hexopyranosyl)-β-D-arabino-hexopyranosyl]oxy]-3-[(O-2,6-dideoxy-3-C-methyl-β-D-ribo-hexopyranosyl-(1→3)-O-2,6-dideoxy-β-D-arabino-hexopyranosyl-(1→3)-2,6-dideoxy-β-D-lyxo-hexopyranosyl)oxy]-1,2,3,4-tetrahydro-5,10-dihydroxy-6-methyl-4-oxo-2-anthracenyl]-1-O-methyl-D-threo-2-pentulose; A 2371; Antibiotic LA 7017; Aureolic acid; Mithracin; Mithramycin A; Mitramycin; NSC 24559; PA 144; Plicamycin; Plicatomycin. Grade: ≥95% by HPLC. CAS No. 18378-89-7. Molecular formula: C52H76O24. Mole weight: 1085.14. | |
| Mithramycin A | Mithramycin A. Group: Biochemicals. Alternative Names: Aureolic acid. Grades: Highly Purified. CAS No. 18378-89-7. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C52H76O24. US Biological Life Sciences. | Worldwide |
| Mithramycin A | 5mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C52H76O24. CAS No. 18378-89-7. Prepack ID 50053396-5mg. Molecular Weight 1085.15. See USA prepack pricing. |  |
| Mitiglinide Acyl- β-D-glucuronide | Mitiglinide Acyl- β-D-glucuronide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H33NO9, Molecular Weight: 491.53. US Biological Life Sciences. | Worldwide |
| Mitiglinide calcium | Mitiglinide Calcium is a blood glucose-lowering drugs, stimulating insulin secretion by closing the ATP-sensitive K+ channels in pancreatic beta-cells. Synonyms: KAD-1229; KAD 1229; KAD1229. Grade: >98%. CAS No. 145525-41-3. Molecular formula: (C19H24NO3)2.Ca. Mole weight: 668.88. | |
| Mitiglinide calcium | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H24NO3 ·0.5Ca. CAS No. 145525-41-3. Prepack ID 23856829-100mg. Molecular Weight 334.44. See USA prepack pricing. | |
| Mitiglinide Calcium | Mitiglinide calcium hydrate, a derivative of benzylsuccinic acid, is a highly selective KATP channel antagonist. Category: Hypoglycemic apis. Synonyms: Mitiglinide calcium hydrate. Mitiglinide calcium dihydrate. Glufast. UNII-9651C21W3Z. CAS No. 207844-01-7. Product ID: API207844017. Molecular formula: C38H52CaN2O8. Mole weight: 704.9. EINECS: 691-325-2. SMILES: C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)[O-].C1CCC2CN(CC2C1)C(=O)CC(CC3=CC=CC=C3)C(=O)[O-].O.O.[Ca+2]. Appearance: White or off-white crystalline powder. Standard: In-house. |  |
| Mitiglinide calcium hydrate | Mitiglinide calcium hydrate (KAD-1229), an insulinotropic agent, is an ATP-sensitive K+ (KATP) channel antagonist. Mitiglinide calcium hydrate is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATP channel). Mitiglinide Calcium hydrate can be used for the research of type 2 diabetes[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KAD-1229; S-21403. CAS No. 207844-01-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0682A. | |
| Mitiglinide impurity 1 | Mitiglinide impurity 1. Uses: For analytical and research use. Molecular formula: C19H25NO3. Mole weight: 315.41. Catalog: APB11817. | |
| Mitiglinide Impurity 2 | Mitiglinide Impurity 2. Uses: For analytical and research use. Alternative Names: (1R,2S)-cyclohexane-1,2-dicarboxylic acid. CAS No. 610-09-3. Molecular formula: C8H12O4. Mole weight: 172.18. Catalog: APB610093. | |
| Mitiperstat | Mitiperstat (AZD4831) is an effective oral inhibitor of myeloperoxidase (MPO). Mitiperstat inhibits MPO and thyroid peroxidase (TPO) with IC50s of 1.5 nM and 0.69 μM. Mitiperstat exhibits a weak inhibitory activity against CYP3A4 with an IC50 of 6 μM. Mitiperstat can reduce inflammation and improve microvascular function, and it can be used in studies related to heart failure, preserved or mildly reduced ejection fraction, non-alcoholic fatty liver disease, and chronic obstructive pulmonary disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD4831. CAS No. 1933460-19-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145581. | |
| Mitiromycin A2 | Mitiromycin A2 is a quinone antibiotic produced by Streptorverticilliim verticillatus AA-849, AB-286. It has weak anti-Gram-positive bacteria activity. Synonyms: Mitiromycin; 2-Hydroxy-6-methoxy-7,11-dimethyl-4,4a,10,10a,11,11a-hexahydroazireno[2',3':3,4]pyrrolo[1,2-a][1,3]oxazino[4,5-b]indole-5,8-dione. CAS No. 27164-43-8. Molecular formula: C16H17N3O5. Mole weight: 331.32. | |
| MitMAB | MitMAB. Group: Biochemicals. Grades: Purified. CAS No. 1119-97-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MitoBADY | MitoBADY is a mitochondria-selective Raman probe that successfully visualizes mitochondria in live HeLa cells at a concentration of 200-400 nM for 10 minutes. MitoBADY can be utilized for the study of mitochondrial dynamics[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1644119-76-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-123583. | |
| MitoBloCK-1 | MitoBloCK-1 (MB-1) is an inhibitor that blocks the import of substrates that use the TIM22 import pathway. MitoBloCK-1 inhibits import by preventing binding of substrate to tim9/10 complex to the substrate, thus the substrate failed to be reach the TIM22 translocon. MitoBloCK-1 inhibits protein import of TIM22 substrates into mitochondria. MitoBloCK-1 attenuates the import of the carrier proteins including the ADP/ATP and phosphate carriers. MitoBloCK-1 also inhibits the import of an additional carrier protein, PiC, and the outer membrane protein Tom40[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MB-1. CAS No. 373370-73-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122658. | |
| MitoBloCK-10 | MitoBloCK-10 (MB-10) is the first small molecule modulator to attenuate protein-associated motor (PAM) complex activity. MitoBloCK-10 (MB-10) inhibits Tim44 (C-terminal domain) binding to the precursor and to Hsp70[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 394694-98-5. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115467. | |
| MitoBloCK-6 | MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce Apoptosis via cytochrome c release. MitoBloCK-6 inhibits growth of developing zebrafish motor neurons. MitoBloCK-6 has anticancer activity against liver cancer and leukemia[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 303215-67-0. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-122652. | |
| MitoBloCK-6 (2- ( ( (4-Anilinophenyl) imino) methyl) -4, 6-dichlorophenol, 2, 4-Dichloro-6- ( ( ( ( (phenylamino) phenyl) imino) methyl) phenol) , Mitochondrial Protein Import Blocker from the Carla Koehler Laboratory, MB6, MB-6) | A cell-permeable, stable dichlorosalicylalde hyde Schiff's base that acts as a potent, selective inhibitor of Mia40/Erv1 redox-mediated import pathway (IC50 = 700nM, 900nM, and 1.4uM for ALR, Erv1, and Erv2, respectively). Significantly reduces the import of CX9 proteins, Erv1, Tim23, and ADP/ATP carrier (AAC). However, it does not affect mitochondrial membrane integrity as evidenced by the lack of aconitase, AAC, Tim54, Mia40, and cytochrome c release. Has no effect on protein disulfide isomerase, flavin adenine dinucleotide, and succinate dehydrogenase activities and does not disrupt mitochondrial net work or reduce viability of cells even at high concentrations (~100uM in HeLa and HEK293 cells). Reported to specifically cause cytochrome c release, activate caspase-3, and induce apoptosis in human embryonic stem cells (~20uM), but not in differentiated cells. Reversibly impairs cardiac development and reduces heart rate in zebra fish that is attributed to mitochondrial dysfunction. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??Cl?N?O, Primary Target: Erv1. US Biological Life Sciences. | Worldwide |
| Mitochondrial ATF Translocator, SBI-0087702 (N- ( (4-methoxynaphthalen-1-yl) methyl) -2- (4-methoxyphenyl) ethanamine, SBI0087702, SBI 0087702) | A cell permeable naphthalene derivative that promotes the translocation of ATF2 from nucleus to mitochondria via PKCe that results in mitochondrial membrane leakage and cell death in melanoma cells (WM793 and UACC903). Diminishes cell motility and anchorage-free growth in melanoma cells (<90% at 10uM) and reduces their migration in an ATF2-dependent manner. Shown to reduce ATF2 phosphorylation on Thr52, 69, and 71. However, it does not affect the activity of Erk1/2, Akt, pan-PKC. Cells expressing ATF2T52E do not exhibit any loss of mitochondrial membrane potential. Does not induce apoptosis in normal melanocytes even at high concentrations (~20 mM) and has no effect on the localization or translocation of p53, STAT3, or b-catenin. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Mitochondrial fusion promoter M1 | Mitochondrial fusion promoter M1 is a mitochondrial dynamic modulator. Mitochondrial fusion promoter M1 preserves the mitochondrial function and promotes cellular respiration. Mitochondrial fusion promoter M1 alleviates cardiac and brain damage in rats with cardiac ischemia/reperfusion injury[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 219315-22-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111475. | |
| Mitochondrial Fusion Promoter, M1 ( (E) -4-Chloro-2- (1- (2- (2, 4, 6-trichlorophenyl) hydrazono) ethyl) phenol) | A cell-permeable phenylhydrazone that restores mitochondrial tubular network formation in MEF lacking either of the two outer mitochondrial membrane (OMM) mitofusins (EC50=5.3 and 4.42 mM, respectively, in Mfn1 or Mfn2 knockout MEF cells) or in MPP+-treated SH-SY5Y cells (5uM 24h), but not in MEF lacking both Mfn1/2 or the inner mitochondrial membrane (IMM) fusion mediator Opa1 (optic atrophy1). M1 (5uM 24h) is reported to boost the downregulated ATP5A & ATP5B protein level in Mfn1 or Mfn2 knockout MEF to the wild-type MEF level and ATPase inhibitor oligomycin at 5uM is shown to completely offset the mitochondrial fusion effect by 5uM M1 in Mfn1 knockout MEF. Comparing to mdivi-1, M1 exerts its effect via promoting fusion rather than inhibiting fission or division. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| mitochondrial intermediate peptidase | A homologue of thimet oligopeptidase. Natural substrates are precursor proteins that have already been processed by mitochondrial processing peptidase. In peptidase family M3 (thimet oligopeptidase family). Group: Enzymes. Synonyms: mitochondrial intermediate precursor-processing proteinase; MIP. Enzyme Commission Number: EC 3.4.24.59. CAS No. 136447-30-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4341; mitochondrial intermediate peptidase; EC 3.4.24.59; 136447-30-8; mitochondrial intermediate precursor-processing proteinase; MIP. Cat No: EXWM-4341. |  |
| mitochondrial processing peptidase | Known from the mitochondrial matrix of fungi and mammals. Formed from two subunits, both homologous with pitrilysin, and the products of the MAS1 and MAS2 genes in yeast. In peptidase family M16 (pitrilysin family). Group: Enzymes. Synonyms: processing enhancing peptidase (for one of two subunits); mitochondrial protein precursor-processing proteinase; matrix peptidase; matrix processing peptidase; matrix processing proteinase; mitochondrial protein precursor-processing proteinase; MPP. Enzyme Commission Number: EC 3.4.24.64. CAS No. 86280-61-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4347; mitochondrial processing peptidase; EC 3.4.24.64; 86280-61-7; processing enhancing peptidase (for one of two subunits); mitochondrial protein precursor-processing proteinase; matrix peptidase; matrix processing peptidase; matrix processing proteinase; mitochondrial protein precursor-processing proteinase; MPP. Cat No: EXWM-4347. | |
| mitochondrial protein-transporting ATPase | A non-phosphorylated, non-ABC (ATP-binding cassette) ATPase involved in the transport of proteins or preproteins into mitochondria using the TIM protein complex. (TIM is the protein transport machinery of the inner mitochondrial membrane that contains three essential Tim proteins: Tim17 and Tim23 are thought to build a preprotein translocation channel while Tim44 interacts transiently with the matrix heat-shock protein Hsp70 to form an ATP-driven import motor.). Group: Enzymes. Enzyme Commission Number: EC 7.4.2.3 (Formerly EC 3.6.3.51). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4690; mitochondrial protein-transporting ATPase; EC 3.6.3.51. Cat No: EXWM-4690. | |
| Mitochondrial Pyruvate Carrier Inhibitor, UK5099 ((E)-2-Cyano-3-(1-phenyl-1H-indol-3-yl)acrylic acid, (E)-2-Cyano-3-(1-phenyl-1H-indol-3-yl)-2-propenoic acid, MPC Inhibitor, PF-1005023) | A cell-permeable alpha-cyanocinnamate compound that acts as a rapid, active site thiol modifying, time-dependent and non-competitive inhibitor of bi-directional pyruvate transport across plasma membranes in yeast, bacteria, Drosophila, and humans (IC50 = 50nM in rat heart mitochondria; Ki ≤1uM) with excellent selectivity over monocarboxylates and anions. Shown to significantly decrease pyruvate-driven respiration, enhance glucose uptake and activate AMPK (2uM in human myocytes and skeletal muscle myotubes). Group: Biochemicals. Grades: Highly Purified. CAS No. 56396-35-1. Pack Sizes: 5mg, 25mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. | Worldwide |
| mitochondrial tRNA pseudouridine27/28 synthase | The mitochondrial enzyme Pus2p is specific for position 27 or 28 in mitochondrial tRNA. Group: Enzymes. Synonyms: Pus2; Pus2p; RNA:pseudouridine synthases 2. Enzyme Commission Number: EC 5.4.99.44. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5586; mitochondrial tRNA pseudouridine27/28 synthase; EC 5.4.99.44; Pus2; Pus2p; RNA:pseudouridine synthases 2. Cat No: EXWM-5586. | |
| Mitochondria-Targeted Compound Library | A unique collection of 447 promising or approved mitochondria-targeted compounds including Idebenone, the only approved drug targeting mitochondria, for research in mitochondrial medicine; - Targets include mitochondria related targets, such as ATPase, mitochondria-associated hexokinase, Bcl-2, NADP, etc. and inhibitors for the autophagy initiating factor, ULK1, also include other promising mitochondria-targeted compounds such as lonidamine, paclitaxel, etc; - Bioactivity and safety confirmed by pre-clinical research and clinical trials; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L5300. Categories: Mitochondria-Targeted Compounds Libraries. |  |
| Mitochonic acid 5 | Mitochonic acid 5 binds mitochondria and ameliorates renal tubular and cardiac myocyte damage. Mitochonic acid 5 modulates mitochondrial ATP synthesis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MA-5. CAS No. 1354707-41-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111536. | |
| Mitochonic Acid 5 | Mitochonic Acid 5. Alternative Names: Mitochonic Acid 5; MA-5; MA 5; MA5. CAS No. 1354707-41-7. Purity: >98%. Product ID: ACM1354707417. Molecular formula: C18H13F2NO3. Mole weight: 329.30. IUPAC Name: 4-(2,4-Difluorophenyl)-2-(1H-indol-3-yl)-4-oxobutanoic acid. Alfa Chemistry - ISO 9001:32057 Certified. | |
| MitoEbselen-2 chloride | MitoEbselen-2 chloride (MitoPeroxidase 2), a mitochondria-targeted mimic of glutathione peroxidase, is a radiation mitigator. MitoEbselen-2 chloride is effective in reducing lipid hydroperoxides, preventing apoptotic cell death[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MitoPeroxidase 2. CAS No. 1638973-78-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-139381. | |
| Mitofusin 2 Antibody [J12N7] | MFN2,Mfn2 / Mitofusin 2,Mitofusin 2,Mitofusin-2. Group: Antibodies. Alternative Names: MFN2,Mitofusin-2. Pack Sizes: 20uL. Product ID: F0566. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| mitogen-activated protein kinase | Phosphorylation of specific tyrosineand threonine residues in the activation loop of this enzyme by EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) is necessary for enzyme activation. Once activated, the enzyme phosphorylates target substrates on serine or threonine residues followed by a proline. A distinguishing feature of all MAPKs is the conserved sequence Thr-Xaa-Tyr (TXY). Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth.pk; PMK-1; PMK-2; PMK-3; pp42; pp44mapk; p44mpk; SAPK; STK26; stress-activated protein kinase. Enzyme Commission Number: EC 2.7.11.24. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3144; mitogen-activated protein kinase; EC 2.7.11.24; c-Jun N-terminal kinase; Dp38; ERK; ERK1; ERK2; extracellular signal-regulated kinase; JNK; JNK3α1; LeMPK3; MAP kinase; MAP-2 kinase; MAPK; MBP kinase I; MBP kinase II; microtubule-associated protein 2 kinase; microtubule-associated protein kinase; myelin basic protein kinase; p38Δ; p38-2; p42 mitogen-activated protein kinase; p42mapk; PMK-1; PMK-. | |
| Mitogen activated protein kinase from rat, Recombinant | Mitogen-activated protein kinases (MAPK) are protein kinases that are specific to the amino acids serine, threonine, and tyrosine. MAPKs belong to the CMGC (CDK/MAPK/GSK3/CLK) kinase group. MAPKs are involved in directing cellular responses to a diverse array of stimuli, such as mitogens, osmotic stress, heat shock and proinflammatory cytokines. They regulate cell functions including proliferation, gene expression, differentiation, mitosis, cell survival, and apoptosis. > 95% (sds-page), buffered aqueous glycerol solution, recombinant, expressed in e. coli (n-terminal histidine tagged). Group: Enzymes. Synonyms: ERK2; Extracellular-signal regulated kinase; MAP Kinase Activated from rat; MAPK; Mitogen activated protein kinase. Purity: > 95% (SDS-PAGE). MAP kinase. Mole weight: mol wt 42 kDa. Activity: > 500 U/mg. Stability: -70°C. Form: buffered aqueous glycerol solution. Source: E. coli. Species: Rat. ERK2; Extracellular-signal regulated kinase; MAP Kinase Activated from rat; MAPK; Mitogen activated protein kinase. Pack: vial of 100 ng. Cat No: NATE-0443. | |
| mitogen-activated protein kinase kinase | This enzyme is a dual-specific protein kinase and requires mitogen-activated protein kinase kinase kinase (MAPKKK) for activation. It is required for activation of EC 2.7.11.24, mitogen-activated protein kinase. Phosphorylation of MEK1 by Raf involves phosphorylation of two serine residues. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.g. insulin and growth hormone), mitogens (e.g. epidermal growth factor and platelet-derived growth factor), vasoactive peptides (e.g. angiotensin-II and endothelin), inflammatory cytokines of the tumour necrosis factor (TNF) family and environmental stresses such as osmotic shock, ionizing radiation and ischaemic injury. Group: Enzymes. Synonyms: MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK. Enzyme Commission Number: EC 2.7.12.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3162; mitogen-activated protein kinase kinase; EC 2.7.12.2; MAP kinase kinase; MAP kinase kinase 4; MAP kinase kinase 7; MAP kinase or ERK kinase; MAP2K; MAPKK; MAPKK1; MEK; MEK1; MEK2; MKK; MKK2; MKK4; MKK6; MKK7; STK27. Cat No: EXWM-3162. | |
Our database is helping our users find suppliers everyday.
