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Product
mitogen-activated protein kinase kinase kinase This enzyme phosphorylates and activates its downstream protein kinase, EC 2.7.12.2, mitogen-activated protein kinase kinase (MAPKK) but requires MAPKKKK for activation. Some members of this family can be activated by p21-activated kinases (PAK/STE20) or Ras. While c-Raf and c-Mos activate the classical MAPK/ERK pathway, MEKK1 and MEKK2 preferentially activate the c-Jun N-terminal protein kinase(JNK)/stress-activated protein kinase (SAPK) pathway. Mitogen-activated protein kinase (MAPK) signal transduction pathways are among the most widespread mechanisms of cellular regulation. Mammalian MAPK pathways can be recruited by a wide variety of stimuli including hormones (e.mes. Synonyms: cMos; cRaf; MAPKKK; MAP3K; MAP kinase kinase kinase; MEKK; MEKK1; MEKK2; MEKK3; MEK kinase; Mil/Raf; MLK-like mitogen-activated protein triple kinase; MLTK; MLTKa; MLTKb; REKS; STK28. Enzyme Commission Number: EC 2.7.11.25. CAS No. 146702-84-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3145; mitogen-activated protein kinase kinase kinase; EC 2.7.11.25; 146702-84-3; cMos; cRaf; MAPKKK; MAP3K; MAP kinase kinase kinase; MEKK; MEKK1; MEKK2; MEKK3; MEK kinase; Mil/Raf; MLK-like mitogen-activated protein triple kinase; MLTK; MLTKa; MLTKb; REKS; STK28. Cat No: EXWM-3145. Creative Enzymes
Mitogenic Pentapeptide Mitogenic Pentapeptide represents a potent activator for monocytes/macrophages and B lymphocytes. Synonyms: Tripalmitoyl pentapeptide; Bppp-cssaa; P3C-Ssna; Pam3Cys-ser-ser-asn-ala; 2,3-Bis(palmitoyloxy)propyl-N-palmitoylpentapeptide. CAS No. 87173-03-3. Molecular formula: C67H124N6O14S. Mole weight: 1269.80. BOC Sciences 11
Mitoglitazone Mitoglitazone. Uses: For analytical and research use. CAS No. 146062-49-9. Mole weight: 370.42. Catalog: AP146062499. Alfa Chemistry Analytical Products
Mitoguazone Mitoguazone (Methylglyoxal-bis(guanylhydrazone)) is a synthetic polycarbonyl derivative with potent antineoplastic activity. Mitoguazone is a brain-penetrant and competitive S-adenosyl-methionine decarboxylase (SAMDC) inhibitor that disrupts polyamine biosynthesis. Mitoguazone induces cell apoptosis. Mitoguazone inhibits HIV DNA integration into the cellular DNA in both monocytes and macrophages. Mitoguazone has the potential for acute leukemia, Hodgkin's and non-Hodgkin's lymphoma treatment[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Methylglyoxal-bis(guanylhydrazone); MGBG; Methyl-GAG. CAS No. 459-86-9. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106634. MedChemExpress MCE
Mito-LND Mito-LND (Mito-Lonidamine) is an orally active and mitochondria-targeted inhibitor of oxidative phosphorylation (OXPHOS). Mito-LND inhibits mitochondrial bioenergetics, stimulates the formation of reactive oxygen species, and induces autophagic cell death in lung cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mito-Lonidamine. CAS No. 2361564-49-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134832. MedChemExpress MCE
mitomycin 6-O-methyltransferase The enzyme, characterized from the bacterium Streptomyces lavendulae, is involved in the biosynthesis of the quinone-containing antibiotics mitomycin A and mitomycin B. Group: Enzymes. Synonyms: MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect). Enzyme Commission Number: EC 2.1.1.316. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1924; mitomycin 6-O-methyltransferase; EC 2.1.1.316; MmcR; mitomycin 7-O-methyltransferase (incorrect); S-adenosyl-L-methionine:7-demethylmitomycin-A 7-O-methyltransferase (incorrect). Cat No: EXWM-1924. Creative Enzymes
Mitomycin A Mitomycin A is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Synonyms: Mitomycin EP Impurity B; Mitiromycin B. Grade: > 95%. CAS No. 4055-39-4. Molecular formula: C16H19N3O6. Mole weight: 349.34. BOC Sciences
Mitomycin B Mitomycin B is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. It has an inhibitory effect on tumors. Synonyms: Mitomycin EP Impurity C; (1aS)-8α-[[(Aminocarbonyl)oxy]methyl]-1,1aα,2,8,8aα,8bα-hexahydro-1,5-dimethyl-8a-hydroxy-6-methoxyazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; [1aS-(1aalpha,8alpha,8aalpha,8balpha)]-8-[[(Aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-6-methoxy-1,5-dimethyl-azirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione. Grade: > 95%. CAS No. 4055-40-7. Molecular formula: C16H19N3O6. Mole weight: 349.34. BOC Sciences
Mitomycin C An antitumor antibiotic. It is used as antineoplastic. Group: Biochemicals. Alternative Names: [1aS-(1aα,8 β , 8aα , 8bα ) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, ’3’: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione; MMC; Ametycine; Mutamycin; Mitonco; Mitoplus. Grades: Highly Purified. CAS No. 50-07-7. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 2
Worldwide
Mitomycin C Mitomycin C (Ametycine) is an antineoplastic antibiotic by inhibiting DNA synthesis, used to treat different cancers. Mitomycin C induces apoptosis in a caspases-dependent and Fas/CD95-independent manner.This product is a hazardous chemical (acute toxicity / flammable / skin corrosive). Please use it while wearing a protective face mask, gloves, and clothing. Group: Inhibitors. Alternative Names: Ametycine. CAS No. 50-07-7. Pack Sizes: 10mg. Product ID: S8146. Formula: C15H18N4O5. Smiles: CC1=C(C(=O)C2=C(C1=O)N3CC4C(C3(C2COC(=O)N)OC)N4)N. Storage Conditions: 2 years -80 in solvent. Selleck Chemicals
United States; Europe
Mitomycin C Mitomycin C is a quinone mitomycin antibiotic produced by Str. caespitosus NRRL 2564. It has antibacterial, antimycobacterial and antiviral activities. And it has an inhibitory effect on tumors. Uses: Mitomycin c is also available as a a 4% mixture in nacl. see "mitomycin c+nacl" sample coa. Synonyms: Mitiromycin E; Mutamycin; Ametycine; Zilimeisu. Grade: Assay ≥ 970 mg/g Mitomycin. CAS No. 50-07-7. Molecular formula: C15H18N4O5. Mole weight: 334.33. BOC Sciences
Mitomycin C 2mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H18N4O5. CAS No. 50-07-7. Prepack ID 17545348-2mg. Molecular Weight 334.33. See USA prepack pricing. Molekula Americas
Mitomycin C 25mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H18N4O5. CAS No. 50-07-7. Prepack ID 17545348-25mg. Molecular Weight 334.33. See USA prepack pricing. Molekula Americas
Mitomycin C-[13C,d3] An isotope labelled Mitomycin C, which is a DNA crosslinking agent that inhibits DNA synthesis and induces apoptosis in a variety of cells. Synonyms: Mitomycin C-13C,d3; ((1aS,8S,8aR,8bS)-6-Amino-8a-methoxy-5-(methyl-13C-d3)-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazirino[2',3':3,4]pyrrolo[1,2-a]indol-8-yl)methyl carbamate. Grade: > 95%. Molecular formula: C14[13C]H15D3N4O5. Mole weight: 338.34. BOC Sciences 2
Mitomycin C Pure (NaCl-Free) Supplied as a pure preparation of Mitomycin C. This preparation contains no sodium chloride. Group: Biochemicals. Alternative Names: Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS- (1aa, 8b, 8aa, 8ba) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, ’3’: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Molecular Biology Grade. CAS No. 50-07-7. Pack Sizes: 4mg, 12mg, 24mg, 40mg. US Biological Life Sciences. USBiological 1
Worldwide
Mitomycin C w/NaCl Supplied as a preparation of Mitomycin C with sodium chloride in a ratio of 2mg Mitomycin C and 48mg sodium chloride. Group: Biochemicals. Alternative Names: Streptomyces caespitosus; Ametycine; MMC; Mutamycin; [1aS- (1aa, 8b, 8aa, 8ba) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-methoxy-5-methylazirino[2, ’3’: 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Molecular Biology Grade. CAS No. 50-07-7. Pack Sizes: 2mg. US Biological Life Sciences. USBiological 1
Worldwide
Mitomycin D Mitomycin D. Group: Biochemicals. Alternative Names: (1aS, 8R, 8aR, 8bS) -6-Amino-8-[[ (aminocarbonyl) oxy]methyl]-1, 1a, 2, 8, 8a, 8b-hexahydro-8a-hydroxy-1, 5-dimethylazirino[2', 3': 3, 4]pyrrolo[1, 2-a]indole-4, 7-dione. Grades: Highly Purified. CAS No. 10169-34-3. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C15H18N4O5. US Biological Life Sciences. USBiological 5
Worldwide
Mitomycin D Mitomycin D is a mito-mycin antibiotic produced by Streptomyces caespitosus with anti-tumor activity. It is also a semi-synthetic antibiotic with anti-leukemic properties. Uses: An antitumor antibiotic. it is used as antineoplastic. Synonyms: 7-Demethoxy-7-aminomitomycin B; (1aS,8R,8aR,8bS)-6-Amino-8-[[(aminocarbonyl)oxy]methyl]-1,1a,2,8,8a,8b-hexahydro-8a-hydroxy-1,5-dimethylazirino[2',3':3,4]pyrrolo[1,2-a]indole-4,7-dione; [(1aS,8S,8aR,8bS)-6-Amino-8a-hydroxy-1,5-dimethyl-4,7-dioxo-1,1a,2,4,7,8,8a,8b-octahydroazireno[2',3':3,4]pyrrolo[1,2-a]indol-8-yl]methylcarbamate; Azirino(2',3':3,4)pyrrolo(1,2-a)indole-4,7-dione, 1,1a,2,8,8a,8b-hexahydro-6-amino-8-(((aminocarbonyl)oxy)methyl)-1,5-dimethyl-8a-hydroxy-, (1aS-(1a-α,8-β,8a-α,8b-α))-; BRN 4720574; NSC 123106. Grade: 95%. CAS No. 10169-34-3. Molecular formula: C15H18N4O5. Mole weight: 334.33. BOC Sciences
Mitomycin EP Impurity A Mitomycin EP Impurity A. Uses: For analytical and research use. CAS No. 621-79-4. Molecular formula: C9H9NO. Mole weight: 147.17. Catalog: APB621794. Alfa Chemistry Analytical Products 4
Mitomycin EP Impurity B Mitomycin EP Impurity B. Uses: For analytical and research use. CAS No. 4055-39-4. Molecular formula: C16H19N3O6. Mole weight: 349.34. Catalog: APB4055394. Alfa Chemistry Analytical Products 4
Mitomycin EP Impurity C Mitomycin EP Impurity C. Uses: For analytical and research use. CAS No. 4055-40-7. Molecular formula: C16H19N3O6. Mole weight: 349.34. Catalog: APB4055407. Alfa Chemistry Analytical Products 4
Mitomycin EP Impurity D Mitomycin EP Impurity D. Uses: For analytical and research use. CAS No. 111750-67-5. Molecular formula: C15H18N4O5. Mole weight: 334.33. Catalog: APB111750675. Alfa Chemistry Analytical Products 2
Mitonafide A Naphthalimides with potent anticancer activity. Group: Biochemicals. Alternative Names: 2-[2-(Dimethylamino)ethyl]-5-nitro-1H-benz[de]isoquinoline-1,3(2H)-dione. Grades: Highly Purified. CAS No. 54824-17-8. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 2
Worldwide
Mitonafide Mitonafide (NSC 300288) is a cytostatic agent. Mitonafide binds to double-stranded DNA through intercalation, and inhibits DNA and RNA synthesis. Mitonafide is an antitumor agent that can be used in the research of cancers, such as non-small cell lung cancer (NSCLC), leukemia[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NSC 300288. CAS No. 54824-17-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119182. MedChemExpress MCE
mitoNEET Inhibitor NL-1, Thiazolidinedione (5-(3,5-di-tert-butyl-4-hydroxybenzyl)-4-hydroxythiazol-2(5H)-one) A cell-permeable, thiazolidinedione (TZD) that acts as an inhibitor of MitoNEET (IC50=0.9uM) in competition with rosiglitazone and pioglitazone, in liver mitochondrial suspensions. In pharmacological studies, it was found to alter isolated mitochondrial complex I respiration with an IC50 of 2.4uM and inhibited State III respiration up to 45%. Furthermore, this compound (6-25uM) is shown to dose-dependently reduce lactate-dehydrogenase release in SH-SY5Y cultures, leading to a 40% decrease in rotenone-induced cell-death. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
MitoPerOx MitoPerOx is a mitochondrial-targeted, lipid peroxidation-indicating fluorescent probe with BODIPY581/591 fluorophores. The triphenylphosphine cation (TPP+) of MitoPerOx can be selectively enriched in mitochondria (depending on membrane potential) and can be used to detect lipid peroxidation in the inner mitochondrial membrane. Under the action of lipid peroxides, the BODIPY581/591 fluorophores of MitoPerOx shift their emission wavelength from 590 nm (reduced state) to 520 nm (oxidized state), and ratiometric detection can be performed at an excitation wavelength of 488 nm. MitoPerOx can specifically monitor the peroxidation of mitochondrial phospholipids (especially cardiolipin) and is used in the study of oxidative stress-related diseases (such as aging, neurodegenerative diseases, and mitochondrial dysfunction)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1392820-50-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-125623. MedChemExpress MCE
MitoPQ MitoPQ is a mitochondria-targeted redox cycler. MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ can be used in antioxidant study[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MitoParaquat. CAS No. 1821370-28-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130278. MedChemExpress MCE
MitoQ (Mitoquinone) Mesylate MitoQ (Mitoquinone) mesylate is a TPP-based, mitochondria-targeted antioxidant that blocks H2O2-induced intracellular ROS responses and protects against oxidative damage. This product is a waxy solid. Group: Inhibitors. Alternative Names: MitoQ10 mesylate, Mitoubiquinone mesylate. CAS No. 845959-50-4. Pack Sizes: 5mg. Product ID: S8978. Formula: C38H47O7PS. Smiles: CC1=C(C(=O)C(=C(C1=O)OC)OC)CCCCCCCCCC[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4.CS(=O)(=O)[O-]. Storage Conditions: 2 years -20°C liquid. Selleck Chemicals
United States; Europe
Mitoquinol Mitoquinol is an orally active mitochondria-targeted antioxidant. Mitoquinol can regulate mitochondrial respiration and oxidation. Mitoquinol inhibits ROS production, and improves phagocytosis and glycolysis in ethanol-exposed macrophages via the HIF-1α-PFKP axis. Additionally, Mitoquinol can partially alleviate heat stress-induced decreases in growth performance, inflammatory responses, and metabolic disorders in pigs[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 845959-55-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-124410. MedChemExpress MCE
Mitoquinone mesylate Mitoquinone mesylate is a TPP-based, mitochondrially targeted antioxidant in order to protect against oxidative damage[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MitoQ mesylate; MitoQ10 mesylate. CAS No. 845959-50-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-100116A. MedChemExpress MCE
Mitoridine Mitoridine. Group: Biochemicals. Grades: Plant Grade. CAS No. 3911-19-1. Pack Sizes: 10mg. Molecular Formula: C20H22N2O2, Molecular Weight: 322.4. US Biological Life Sciences. USBiological 9
Worldwide
Mitorubrin Mitorubrin is a metabolite synthesized by phytotoxic fungi. Synonyms: (-)-Mitorubrin; β-Resorcylic acid, 6-methyl-, ester with 7-hydroxy-7-methyl-3-propenyl-6H-2-benzopyran-6,8(7H)-dione (7CI,8CI). CAS No. 3403-71-2. Molecular formula: C21H18O7. Mole weight: 382.36. BOC Sciences 12
Mitorubrinic acid Mitorubrinic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 58958-07-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C21H16O9. US Biological Life Sciences. USBiological 7
Worldwide
MitoSOX Red MitoSOX Red is a live cell fluorescent probe that specifically targets mitochondria and is cell membrane permeable. MitoSOX Red enters mitochondria and is oxidized by superoxide but not by other ROS or RNS generating systems. The oxidized MitoSOX Red then binds to nucleic acids in mitochondria/nucleus, producing strong red fluorescence. MitoSOX Red can be used as a fluorescent indicator to specifically detect superoxide. In addition, superoxide dismutase (SOD) can prevent the oxidation of MitoSOX Red. Excitation/emission wavelength: 510/580 nm. Uses: Scientific research. Category: Signaling pathways. CAS No. 1003197-00-9. Pack Sizes: 100 μg; 100 μg * 5. Product ID: HY-D1055. MedChemExpress MCE
MitoTam iodide, hydriodide MitoTam iodide, hydriodide is a Tamoxifen derivative[1], an electron transport chain (ETC) inhibitor, spreduces mitochondrial membrane potential in senescent cells and affects mitochondrial morphology[2].MitoTam iodide, hydriodide is an effective anticancer agent, suppresses respiratory complexes (CI-respiration) and disrupts respiratory supercomplexes (SCs) formation in breast cancer cells[1][2]. MitoTam iodide, hydriodide causes apoptosis[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1634624-74-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-126222A. MedChemExpress MCE
Mitotane Mitotane (2,4-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,4-DDD; o,p'-DDD. CAS No. 53-19-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-13690. MedChemExpress MCE
Mitotane Mitotane. Group: Biochemicals. Grades: Highly Purified. CAS No. 53-19-0. Pack Sizes: 2g, 5g, 10g, 25g, 50g. Molecular Formula: C14H10Cl4. US Biological Life Sciences. USBiological 7
Worldwide
Mitotane-13C6 Mitotane-13C6 is the 13C labeled Mitotane[1]. Mitotane (2,4-DDD), an isomer of DDD and derivative of dichlorodiphenyltrichloroethane (DDT), is an antineoplastic agent, can be used to research adrenocortical carcinoma. Mitotane exert its adrenocorticolytic effect at least in part through lipotoxicity induced by intracellular free cholesterol (FC) accumulation. Mitotane can have direct pituitary effects on corticotroph cells. Mitotane can induce CYP3A4 gene expression via steroid and xenobiotic receptor (SXR) activation, and has agent-agent interactions[2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2,4-DDD-13C6; o,p'-DDD-13C6. CAS No. 1261396-21-7. Pack Sizes: 1 mg. Product ID: HY-13690S1. MedChemExpress MCE
Mitotane-13C6 Mitotane-13C6. Group: Biochemicals. Alternative Names: 1-Chloro-2-[2, 2-dichloro-1- (4-chlorophenyl) ethyl]benzene-13C6; 1, 1-Dichloro-2- (o-chlorophenyl) -2- (p-chlorophenyl) ethane-13C6; 1- (2-Chlorophenyl) -1- (4-chlorophenyl) -2, 2-dichloroethane-13C6; 1-(2'-Chlorophenyl)-1-(4'-chlorophenyl)-2,2-dichloroethane-13C6; 1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane-13C6; 2, 4'-Dichlorodiphenyl dichloroethane -13C6; 2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane-13C6; 2-(p-Chlorophenyl)-2-(o-chlorophenyl)-1,1-dichloroethane-13C6; CB 313-13C6; Chloditan-13C6; Chlodithane-13C6; Lysodren-13C6; Mitotan-d4; NSC 38721-13C6; Opeprim-13C6; o,p'-DDD-13C6; o, p'-Dichlorodiphenyl dichloroethane -13C6; o,p'-TD-13C6. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C813C6H10Cl4, Molecular Weight: 326. US Biological Life Sciences. USBiological 3
Worldwide
Mitotane-d4 Mitotane-d4. Group: Biochemicals. Alternative Names: 1-Chloro-2-[2, 2-dichloro-1- (4-chlorophenyl) ethyl]benzene-d4; 1,1-Dichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane-d4; 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane-d4; 1-(2'-Chlorophenyl)-1-(4'-chlorophenyl)-2,2-dichloroethane-d4; 1-(o-Chlorophenyl)-1-(p-chlorophenyl)-2,2-dichloroethane-d4; 2, 4'-Dichlorodiphenyl dichloroethane -d4; 2-(2-Chlorophenyl)-2-(4-chlorophenyl)-1,1-dichloroethane-d4; 2-(p-Chlorophenyl)-2-(o-chlorophenyl)-1,1-dichloroethane-d4; CB 313-d4; Chloditan-d4; Chlodithane-d4; Lysodren-d4; Mitotan-d4; NSC 38721-d4; Opeprim-d4; o,p'-DDD-d4; o, p'-Dichlorodiphenyl dichloroethane -d4; o,p'-TDE-d4. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C14H6D4Cl4, Molecular Weight: 324.07. US Biological Life Sciences. USBiological 3
Worldwide
Mitotane (o,p'-DDD, CB-313, Lysodren,. 1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane) An Antineoplastic. Used as an adrenolytic agent. Group: Biochemicals. Alternative Names: o,p'-DDD, CB-313, Lysodren,1-(2-Chlorophenyl)-1-(4-chlorophenyl)-2,2-dichloroethane. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences. USBiological 1
Worldwide
Mito-TEMPO Mito-TEMPO is a mitochondria-targeted antioxidant. Mito-TEMPO induces mitophagy by activating the PINK1/Parkin pathway, inhibits NLRP3 inflammasome activation, restores mitochondrial membrane potential, and improves renal function and podocyte injury. Mito-TEMPO regulates Ca2+ homeostasis, inhibits Bnip3 overexpression, shortens action potential duration, and exerts antiarrhythmic effects. Mito-TEMPO reverses premature senescence, reduces trabecular bone loss, and decreases cell apoptosis. Mito-TEMPO can be used in studies of chronic kidney disease, age-related cardiac dysfunction, postmenopausal osteoporosis, and ischemic stroke[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1334850-99-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112879. MedChemExpress MCE
Mito-TEMPO Mito-TEMPO (MT), a mitochondria-targeted superoxide dismutase mimetic, protects against the early phase of acetaminophen (APAP) hepatotoxicity by inhibiting peroxynitrite formation. Mito-TEMPO treatment inhibits APAP-induced RIP3 kinase expression. Group: Inhibitors. CAS No. 1334850-99-5. Pack Sizes: 5mg. Product ID: S9733. Formula: C29H35N2O2P.Cl. Smiles: [Cl-].CC1(C)CC(CC(C)(C)N1[O])NC(=O)C[P+](C2=CC=CC=C2)(C3=CC=CC=C3)C4=CC=CC=C4. Selleck Chemicals
United States; Europe
MitoTEMPO hydrate MitoTEMPO hydrate is a mitochondria-targeted antioxidant. MitoTEMPO hydrate induces mitophagy by activating the PINK1/Parkin pathway, inhibits NLRP3 inflammasome activation, restores mitochondrial membrane potential, and improves renal function and podocyte injury. MitoTEMPO hydrate regulates Ca2+ homeostasis, inhibits Bnip3 overexpression, shortens action potential duration, and exerts antiarrhythmic effects. MitoTEMPO hydrate reverses premature senescence, reduces trabecular bone loss, and decreases cell apoptosis. MitoTEMPO hydrate can be used in studies of chronic kidney disease, age-related cardiac dysfunction, postmenopausal osteoporosis, and ischemic stroke[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1569257-94-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125944. MedChemExpress MCE
MitoTEMPOL MitoTEMPOL is a a mitochondria-targeted nitroxide that reduces mitochondrial O2-to H2O2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1101113-39-6. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-115386. MedChemExpress MCE
Mitotic kinesin-IN-1 hydrochloride Mitotic kinesin-IN-1 (Example 80) hydrochloride is a Mitotic kinesin inhibitor. Mitotic kinesin-IN-1 hydrochloride inhibits cell proliferation by suppressing mitosis. Mitotic kinesin-IN-1 hydrochloride can be used for cancer, cardiac hypertrophy, immune and inflammatory disorders, fungal infections research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1018690-45-3. Pack Sizes: 1 mg. Product ID: HY-177246A. MedChemExpress MCE
MitoTracker Deep Red FM MitoTracker Deep Red (MTDR) FM fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Deep Red FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 644/665 nm[1]. MitoTracker Deep Red dyes have an excitation/emission wavelength of 633/650-750 nm[2].The Ex/Em of MitoTracker Deep Red (MTDR) FM is 644/665 nm. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MTDR FM. CAS No. 873315-86-7. Pack Sizes: 50 μg; 100 μg. Product ID: HY-D1783. MedChemExpress MCE
MitoTracker Green FM Mito-Tracker Green is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Green FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 490/523 nm. Uses: Scientific research. Category: Signaling pathways. CAS No. 201860-17-5. Pack Sizes: 50 μg. Product ID: HY-135056. MedChemExpress MCE
MitoTracker Green FM (solution) Mito-Tracker Green (solution) is a green fluorescent dye that selectively accumulates in the mitochondrial matrix. MitoTracker Green FM covalently binds mitochondrial proteins by reacting with free mercaptan of cysteine residues, allowing staining of mitochondrial membrane potential independent of membrane potential. Excitation/emission wavelength 490/523 nm.Solvent and concentration: DMSO: 1 mM. Uses: Scientific research. Category: Signaling pathways. CAS No. 201860-17-5. Pack Sizes: 20 μL; 50 μL. Product ID: HY-DY1032. MedChemExpress MCE
MitoTracker Orange CMTMRos MitoTracker Orange CMTMRos is a fluorescent dye that labels mitochondria within live cells utilizing the mitochondrial membrane potential (Ex/Em: 551/576 nm)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 199116-50-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-D1696. MedChemExpress MCE
Mitoxantrone Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione; 1, 4-Bis [ (2- (2- hydroxyethylamino) ethyl) amino] -5, 8-di hydroxyanthraquinone. Grades: Highly Purified. CAS No. 65271-80-9. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 2
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Mitoxantrone Mitoxantrone is a potent topoisomerase II inhibitor. Mitoxantrone also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone shows antitumor activity[1][2][3][4]. Mitoxantrone also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mitozantrone; NSC 301739. CAS No. 65271-80-9. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-13502. MedChemExpress MCE
Mitoxantrone 50mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H28N4O6. CAS No. 65271-80-9. Prepack ID 28035650-50mg. Molecular Weight 444.48. See USA prepack pricing. Molekula Americas
Mitoxantrone (1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione) An anti-tumor antibiotic and type II topoisomerase inhibitor. It disrupts DNA synthesis and DNA repair in both healthy and cancer cells. Mitoxantrone also displays broad immunosuppressive activity inhibiting proliferation of all classes of lymphocytes and inducing apoptosis of antigen-presenting T cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 65271-80-9. Pack Sizes: 50mg, 250mg. US Biological Life Sciences. USBiological 1
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Mitoxantrone (2-hydroxyethyl) piperazine impurity(mitoxantrone impurity D) Mitoxantrone (2-hydroxyethyl) piperazine impurity(mitoxantrone impurity D). Group: Biochemicals. Alternative Names: 1, 2, 3, 4-Tetrahydro-8, 11-dihydroxy-4- (2-hydroxyethyl) -6- [ [2- [ (2-hydroxyethyl) amino] ethyl] amino] naphtho [2, 3-f] quinoxaline-7, 12-dione; Mitoxantrone impurity D. Grades: Highly Purified. CAS No. 137132-70-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C22H26N4O6. US Biological Life Sciences. USBiological 8
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Mitoxantrone (2-Hydroxyethyl) piperazine Impurity (Mitoxantrone Impurity D) A metabolite of the anticancer agent Mitoxantrone. Group: Biochemicals. Alternative Names: 1, 2, 3, 4-Tetrahydro-8, 11-dihydroxy-4- (2-hydroxyethyl) -6- [ [2- [ (2-hydroxyethyl) amino] ethyl] amino] naphtho [2, 3-f] quinoxaline-7, 12-dione; Mitoxantrone Impurity D. Grades: Highly Purified. CAS No. 137132-70-8. Pack Sizes: 50mg. US Biological Life Sciences. USBiological 2
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Mitoxantrone-d8 (1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione-d8) A DNA intercalating drug. Inhibits DNA synthesis. Used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione-d8. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 1
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Mitoxantrone dihydrochloride It is a type II topoisomerase inhibitor with IC50 of 2.0 μM, 0.42 mM for HepG2 and MCF-7/wt cells, respectively. Mitoxantrone dihydrochloride is an antiviral, antibacterial, antiprotozoal, immunomodulating and antineoplastic anthraquinone derivative. Synonyms: 1,4-dihydroxy-5,8-bis((2-((2-hydroxyethyl)amino)ethyl)amino)anthracene-9,10-dione dihydrochloride; DHAQ; CL-232325; CL 232325; CL232325; Novantrone; Mitroxone; Neotalem; Onkotrone; Pralifan; Mitoxantrone 2HCl; Immunex. Grade: >98%. CAS No. 70476-82-3. Molecular formula: C22H28N4O6.2HCl. Mole weight: 517.40. BOC Sciences
Mitoxantrone dihydrochloride Mitoxantrone dihydrochloride is a potent topoisomerase II inhibitor. Mitoxantrone dihydrochloride also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Mitoxantrone dihydrochloride induces apoptosis of B-CLL (B-chronic lymphocytic leukaemia) cells. Mitoxantrone dihydrochloride shows antitumor activity[1][2][3][4]. Mitoxantrone dihydrochloride also has anti-orthopoxvirus activity with EC50s of 0.25 μM and and 0.8 μM for cowpox and monkeypox, respectively[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mitozantrone dihydrochloride; NSC 301739 dihydrochloride. CAS No. 70476-82-3. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-13502A. MedChemExpress MCE
Mitoxantrone dihydrochloride 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C22H28N4O6 · 2HCl. CAS No. 70476-82-3. Prepack ID 24343907-1g. Molecular Weight 517.4. See USA prepack pricing. Molekula Americas
Mitoxantrone Dihydrochloride Mitoxantrone is a DNA intercalating drug. Mitoxantrone inhibits DNA synthesis. Mitoxantrone is used as an anti-cancer agent. Group: Biochemicals. Alternative Names: 1, 4-Dihydroxy-5, 8-bis[[2-[ (2-hydroxyethyl) amino]ethyl]amino]-9, 10-anthracenedione Hydrochloride; Bisantrone; CL 232315; DHAD; Immunex; Mitoxantrone Hydrochloride; NCI 301739; NSC 301739; Novantron; Novantrone; Novatrone. Grades: Highly Purified. CAS No. 70476-82-3. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 2
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Mitoxantrone EP Impurity A Mitoxantrone EP Impurity A. Uses: For analytical and research use. CAS No. 89991-52-6. Molecular formula: C18H19N3O5. Mole weight: 357.37. Catalog: APB89991526. Alfa Chemistry Analytical Products 4
Mitoxantrone EP Impurity B Mitoxantrone EP Impurity B. Uses: For analytical and research use. CAS No. 80189-44-2. Molecular formula: C22H28N4O5. Mole weight: 428.49. Catalog: APB80189442. Alfa Chemistry Analytical Products 4
Mitoxantrone EP Impurity C Mitoxantrone EP Impurity C. Uses: For analytical and research use. CAS No. 1796928-50-1. Molecular formula: C22H27ClN4O6. Mole weight: 478.93. Catalog: APB1796928501. Alfa Chemistry Analytical Products 3
Mitoxantrone EP Impurity D Mitoxantrone EP Impurity D. Uses: For analytical and research use. CAS No. 137132-70-8. Molecular formula: C22H26N4O6. Mole weight: 442.47. Catalog: APB137132708. Alfa Chemistry Analytical Products 3
Mitoxantrone hydrochloride Mitoxantrone dihydrochloride is a topoisomerase II inhibitor; also inhibits protein kinase C (PKC) activity with an IC50 of 8.5 μM. Category: Active pharmaceutical ingredients. CAS No. 70476-82-3. Product ID: API70476823. Molecular formula: C22H30Cl2N4O6. Mole weight: 517.403. Protheragen
Mitoxantrone Impurity 1 Mitoxantrone Impurity 1. Uses: For analytical and research use. CAS No. 6374-78-3. Molecular formula: C14H9NO5. Mole weight: 271.23. Catalog: APB6374783. Alfa Chemistry Analytical Products 4
Mitoxantrone Impurity2 Mitoxantrone Impurity2. Uses: For analytical and research use. CAS No. 70476-65-2. Molecular formula: C26H32N4O6. Mole weight: 496.56. Catalog: APB70476652. Alfa Chemistry Analytical Products 4
Mitoxantrone Impurity3 Mitoxantrone Impurity3. Uses: For analytical and research use. CAS No. 1160572-37-1. Molecular formula: C30H48N8O6. Mole weight: 616.76. Catalog: APB1160572371. Alfa Chemistry Analytical Products 2
Mitoxantrone Impurity4 Mitoxantrone Impurity4. Uses: For analytical and research use. CAS No. 100204-25-9. Molecular formula: C24H28ClF3N4O7. Mole weight: 576.95. Catalog: APB100204259. Alfa Chemistry Analytical Products 2

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