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| Product | Description | |
|---|---|---|
| MLS001006105 | MLS001006105 (ZINC13684400) is a GPR65 allosteric agonist. MLS001006105 displays GPR65 allosteric agonist activity at pH 8.40 but not at lower pH[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZINC13684400. CAS No. 455310-36-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W193844. |  |
| MLS0315771 | MLS0315771 is a potent and biologically active competitive phosphomannose isomerase (MPI) inhibitor, with an IC50 ~1 μM and a Ki of 1.4 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 727664-91-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112945. | |
| MLS-0437605 | MLS-0437605 is a selective dual-specificity phosphatase 3 (DUSP3) inhibitor with an IC50 of 3.7 μM. MLS-0437605 is more selective for DUSP3 than DUSP22 and other protein tyrosine phosphatases (PTPs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 862975-18-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123846. | |
| ML SA1 | ML SA1. Group: Biochemicals. Grades: Purified. CAS No. 332382-54-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| ML-SA1 | ML-SA1, as a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively. ML-SA1 induces autophagy. ML-SA1 can be used for the research of broad-spectrum antiviral[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 332382-54-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108462. | |
| ML-SA5 | ML-SA5 is a potent TRPML1 cation channel agonist that activates the entire endosomal TRPML1 (ML1) current in DMD myocytes with an EC50 of 285 nM and is more potent than ML-SA1. ML-SA5 has anticancer activity and can inhibit tumour growth[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2418670-70-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-152182. | |
| ML-SI3 | ML-SI3 is a mixture of cis/trans ML-SI3 (HY-139426A), which is a TRPML1/2 channel inhibitor with IC50s of 4.7 μM and 1.7 μM, respectively. ML-SI3 also inhibits lysosomal calcium efflux and blocks downstream TRPML1-mediated autophagy. The cis/trans ML-SI3 (HY-139426A) components of ML-SI3 are TRPML2 activators with EC50s of 3.3 μM and 9.4 μM, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ML-SI3 (cis/trans mix). CAS No. 891016-02-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139426. | |
| ML-T7 | ML-T7 is a potent Tim-3 inhibitor. ML-T7 blocks Tim-3 interactions with PtdSer and CEACAM1. ML-T7 not only enhances the antitumor activity of adoptive transfer therapy with cytotoxic T lymphocytes (CTLs) and CAR T cells but also increases the effector function of T cell. ML-T7 promotes NK cells killing activity against tumor cells and DC antigen-presenting capacity. ML-T7 directly exerts antitumor efficacy in preclinical tumor models either alone or in combination with Nivolumab (HY-P9903A). ML-T7 can be used for tumor immunotherapy research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 459789-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163028. | |
| MLT-943 | MLT-943 is a potent, selective and orally active MALT1 protease inhibitor. MLT-943 inhibits stimulated-IL-2 secretion in PBMC or in whole blood with a similar IC50 across species (0.07-0.09 μM in PBMC, 0.6-0.8 μM in whole blood). MLT-943 has anti-inflammatory activities and can be used for FcgR-mediated inflammation research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1832576-04-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134820. | |
| MLT-985 | MLT-985 is a selective allosteric and orally active MALT1 inhibitor with an IC50 value of 3 nM. MLT-985 can suppress cell growth and aberrant CARD11/BCL10/MALT1 complex signaling. MLT-985 can be used for the research of cancer, such as B cell malignancies[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1832576-25-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142648. | |
| Mlu I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. A↑CGCGT TGCGC↓A. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Micrococcus luteus. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1133RE. |  |
| Mly113 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of T7 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 3-fold overdigestion with enzyme more than 80% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GG↑CGCC CCGC↓GG. Activity: 2000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Micrococcus lylae 113. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1134RE. | |
| MM0299 | MM0299 is a selective lanosterol synthase (LSS) inhibitor with an IC50 value of 2.22 μM. MM0299 depletes intracellular cholesterol and acts as a growth inhibitor for glioma stem-like cells. MM0299 exhibits anti-glioblastoma activity. MM0299 is applicable to research related to glioblastoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 474255-10-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160972. | |
| MM 07 | MM 07 is a biased apelin receptor agonist, with a KD of 300 nM in CHO-K1 cells and a KD of 172 nM in human heart. Uses: Scientific research. Category: Signaling pathways. CAS No. 1876450-21-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-108003. | |
| MM 102 | MM 102. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MM-102 | MM-102 (HMTase Inhibitor IX) is a cell-permeable and tightly binding inhibitor of MLL1-WDR5 interaction (IC50=2.4 nM). MM-102 can specifically inhibit the growth and induce apoptosis of leukemia cells containing MLL1 fusion protein, and reduce renal fibrosis and inflammation in mice with ischemia-reperfusion injury. In addition, MM-102 also acts as an H3K4 histone methyltransferase inhibitor to improve the development of porcine somatic cell nuclear transfer (SCNT) embryos[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMTase Inhibitor IX. CAS No. 1417329-24-8. Pack Sizes: 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12220. | |
| MM-102 | MM-102, as a MLL1 mimetic, shows high binding affinities to WDR5 with IC50 of 2.9 nM and Ki of < 1 nM. Synonyms: MM-102; MM102; MM 102; HMTase Inhibitor IX. Grade:>98%. CAS No. 1417329-24-8. Molecular formula: C35H49F2N7O4. Mole weight: 669.8. |  |
| MM-102 | MM-102 Inhibitor. Uses: Scientific use. Product Category: T8768. CAS No. 1883545-52-5. |  |
| MM-102 TFA | MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor, achieves IC50 = 2.4 nM with an estimated Ki < 1 nM in WDR5 binding assay, which is>200 times more potent than the ARA peptide. Uses: Scientific research. Category: Signaling pathways. Alternative Names: HMTase Inhibitor IX TFA. CAS No. 1883545-52-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-12220A. | |
| MM11253 | MM11253 is a potent and selective RARγ antagonist with an IC50 of 44 nM. MM11253 has lower inhibition of RARα, RARβ and RXRα. MM11253 blocks the growth inhibitory effects of RARγ-selective agonists[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 345952-44-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108530. | |
| MM 11253 | MM 11253. Group: Biochemicals. Grades: Purified. CAS No. 345952-44-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MM 14201 | It is produced by the strain of Streptomyces sp. NCIB 11813. MM 14201 has a broad spectrum of antibacterial activity, especially against the bacteria of Serratia and Pseudomonas. Synonyms: MM-14201; 7-Oxabicyclo(4.1.0)hept-3-en-2-one, 3-amino-5-hydroxy-, (1S-(1alpha,5beta,6alpha))-. CAS No. 89020-30-4. Molecular formula: C6H7NO3. Mole weight: 141.12. | |
| MM-17880 | MM-17880 is originally isolated from Streptomyces olivaceus. It has anti-gram-positive and anti-gram-negative bacteria activities. Combined with amoxycillin, it has a synergistic antibacterial effect on Staphylococcus aureus and Klebsiella pneumoniae. Synonyms: (5R)-3-[[2-(Acetylamino)ethyl]thio]-6α-[(S)-1-(sulfooxy)ethyl]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid disodium salt. CAS No. 61036-81-5. Molecular formula: C13H16N2Na2O8S2. Mole weight: 438.38. | |
| MM-206 | MM-206, a STAT3 activity inhibitor, potently inhibits the STAT3 SH2 domain-phosphopeptide interaction with IC50 of 1.2 μM. MM-206 demonstrates dose-dependent induction of apoptosis in acute myeloid leukemia (AML) cell lines[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1809581-87-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-121725. | |
| MM3122 | MM3122 is a selective type II transmembrane serine protease (TMPRSS2) inhibitor with an IC50 value of 0.34 nM. MM3122 effectively blocks TMPRSS2, thereby inhibiting the entry of SARS-CoV-2 and MERS-CoV into human cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2574390-27-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-148072. | |
| MM-401 TFA | MM-401 (TFA) is a MLL1 H3K4 methyltransferase inhibitor. MM-401 inhibits MLL1 activity (IC50 = 0.32 μM) by blocking MLL1-WDR5 interaction. MM-401 can induce cell cycle arrest, apoptosis and differentiation. MM-401 can be used for the research of MLL leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1442106-11-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-19554A. | |
| MM 42842 | MM 42842 is originally isolated from Pseudomonas cocovenenans and has weak activity against gram-positive bacteria. Synonyms: MM-42842. Grade: >98%. CAS No. 113784-28-4. Molecular formula: C13H22N4O9S. Mole weight: 410.40. | |
| MM 46115 | MM 46115 is produced by the strain of Actinomadura pelletieri. It has anti-parainfluenza virus 1 and 2 and anti-gram-positive bacteria activities. Synonyms: MM-46115; 17-O-(4-((3-Chloro-6-hydroxy-2-methylbenzoyl)amino)-2,3,4,6-tetradeoxy-3-(dimethylamino)-beta-D-lyxo-hexopyranosyl)-22-de(hydroxymethyl)-8,14,23-tridemethyl-12-ethyl-8-hydroxy-23-propylkijanolide. CAS No. 132054-37-6. Molecular formula: C50H67ClN2O10. Mole weight: 891.52. | |
| MM 47755 | MM 47755 is produced by the strain of greysporing streptomycete. It has anti-Gram-negative bacteria and fungi activity (100μg/ mL). Synonyms: 6-Deoxy-8-O-methylrabelomycin; (-)-3,4-Dihydro-3-hydroxy-8-methoxy-3-methylbenz(a)anthracene-1,7,12(2H)-trione; MM-47755; Benz(a)anthracene-1,7,12(2H)-trione, 3,4-dihydro-3-hydroxy-8-methoxy-3-methyl-, (-)-. Grade: 95%. CAS No. 117620-87-8. Molecular formula: C20H16O5. Mole weight: 336.34. | |
| MM 47755 (6-Desoxy-8-O-methylrabelomycin; (R)-3-Hydroxy-8-methoxy-3-methyl-3,4-dihydro-tetraphene-1,7,12(2H)-trione) | Antibiotic. Angucyclinone. Antibacterial and antifungal. Group: Biochemicals. Grades: Highly Purified. CAS No. 117620-87-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| MM 49721 | It is a kind of glycopeptide antibiotic originally isolated from Amycolatatopsis orientalis NCIB 12608 with good activity against Gram-positive bacteria. Synonyms: MM-49721; Vancomycin, 22-O-(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-D-arabino-hexopyranosyl)-2'-O-de(3-amino-2,3,6-trideoxy-3-C-methyl-alpha-L-lyxo-hexopyranosyl)-10,19-didechloro-2'-O-(6-deoxy-alpha-D-talopyranosyl)-. CAS No. 126985-52-2. Molecular formula: C72H87N9O28. Mole weight: 1526.50. | |
| MM 54 | MM 54 (compound 5) is a competitive antagonist at APJ, with an IC50 of 93 nM. MM 54 behaves as a potent and selective inhibitor of apelin binding and APLNR activation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1313027-43-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2271. | |
| MM 54 | MM 54 is an apelin receptor antagonist with IC50 value of 93 nM. It can antagonize the inhibitory effect of [Pyr1]-Apelin-13 on forskolin-induced cAMP accumulation in CHO-K1-APJ cells. Synonyms: MM-54; MM54; H-Cys(1)-Arg-Pro-Arg-Leu-Cys(1)-Lys-His-Cys(2)-Arg-Pro-Arg-Leu-Cys(2)-OH; L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-cysteinyl-L-lysyl-L-histidyl-L-cysteinyl-L-arginyl-L-prolyl-L-arginyl-L-leucyl-L-cysteine (1->6),(9->14)-bis(disulfide). Grade: ≥95%. CAS No. 1313027-43-8. Molecular formula: C70H121N29O15S4. Mole weight: 1737.15. | |
| MM 55266 | It is a kind of glycopeptide antibiotic originally isolated from Amycolatopsis NCIB 40089 with good activity against Gram-positive bacteria. Synonyms: MM-55266; Ristomycin A aglycone, 5,22,31,45,55-pentachloro-7-demethyl-64-O-demethyl-34-O-(2-deoxy-2-((7-methyl-1-oxooctyl)amino)-alpha-D-glucopyranuronosyl)-44-O-beta-D-glucopyranosyl-56-O-beta-D-mannopyranosyl-N15-methyl-. CAS No. 137053-20-4. Molecular formula: C86H89Cl5N8O35. Mole weight: 1971.92. | |
| MM-55268 | It is a kind of glycopeptide antibiotic originally isolated from Amycolatopsis NCIB 40089 with good activity against Gram-positive bacteria. Synonyms: Ristomycin A aglycone, 5,22,31,45,55-pentachloro-7-demethyl-64-O-demethyl-34-O-((2-deoxy-2-((1-oxodecyl)amino)-alpha-D-glucopyranuronosyl)amino)-44-O-beta-D-glucopyranosyl-56-O-beta-D-mannopyranosyl-N15-methyl-. CAS No. 137053-19-1. Molecular formula: C87H91Cl5N8O35. Mole weight: 1985.95. | |
| MM 77 dihydrochloride | MM 77 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 159187-70-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MMAD | Monomethyl auristatin D (MMAD), a potent tubulin inhibitor, is a toxin payload and antibody drug conjugate. Uses: Adcs cytotoxin. Synonyms: Demethyldolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10. Grade: ≥98.0% (HPLC). CAS No. 203849-91-6. Molecular formula: C41H66N6O6S. Mole weight: 771.06. | |
| MMAD | MMAD is a potent tubulin inhibitor, is a toxin payload in antibody agent conjugates (ADCs). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Demethyldolastatin 10; Monomethylauristatin D; Monomethyl Dolastatin 10. CAS No. 203849-91-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15581. | |
| MMAD hydrochloride | Monomethyl auristatin D Hcl (MMAD Hcl), a potent tubulin inhibitor, is a toxin payload in antibody drug conjugate. Uses: Adcs cytotoxin. Synonyms: MMAD HCl. Grade: >98%. CAS No. 173441-26-4. Molecular formula: C41H67ClN6O6S. Mole weight: 807.53. | |
| MMAE | Monomethyl Auristatin E (MMAE) is a synthetic analog of dolastatin 10 that similarly inhibits tubulin polymerization and exhibits potent cytotoxicity. It is commonly conjugated with monoclonal antibodies directed at antigens specific to cancer cells for tumor-directed cytotoxicity. Uses: Adcs cytotoxin. Synonyms: MMAE; Vedotin; Monomethyl auristatin E; Monomethylauristatin E; N-methyl-L-valyl-N-[(3R,4S,5S)-1-{(2S)-2-[(1R,2R)-3-{[(1S,2R)-1-hydroxy-1-phenylpropan-2-yl]amino}-1-methoxy-2-methyl-3-oxopropyl]pyrrolidin-1-yl}-3-methoxy-5-methyl-1-oxoheptan-4-yl]-N-methyl-L-valinamide. Grade: ≥98.0% by HPLC. CAS No. 474645-27-7. Molecular formula: C39H67N5O7. Mole weight: 717.98. | |
| MMAE-d8 | MMAE-d8 is a deuterated labeled MMAE, a potent mitotic inhibitor and a tubulin inhibitor. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Monomethyl auristatin E-d8; Deuterated labeled MMAE. CAS No. 2070009-72-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-15162A. | |
| MMAE-[d8] | MMAE-[d8] is a labelled analogue of MMAE, which is a potent mitotic inhibitor and a tubulin inhibitor. Synonyms: D8-MMAE; D8-Monomethyl auristatin E. Grade: 98% by HPLC; 98% atom D. CAS No. 2070009-72-0. Molecular formula: C39H59D8N5O7. Mole weight: 726.03. | |
| MMAE (Monomethyl auristatin E) | MMAE (Monomethyl auristatin E) is a synthetic antineoplastic agent. It is also a microtubule-disrupting agent. Group: Inhibitors. Alternative Names: SGD-1010. CAS No. 474645-27-7. Pack Sizes: 1mg. Product ID: S7721. Formula: C39H67N5O7. . Smiles: CCC(C)C(C(CC(=O)N1CCCC1C(C(C)C(=O)NC(C)C(C2=CC=CC=C2)O)OC)OC)N(C)C(=O)C(C(C)C)NC(=O)C(C(C)C)NC. Storage Conditions: -20°C power 3 years. |  United States; Europe |
| MMAE-SMCC | MMAE-SMCC is a agent-linker conjugate for ADC. MMAE-SMCC is composed of a potent mitotic and a tubulin inhibitor MMAE and a linker SMCC to make antibody agent conjugate. Uses: Scientific research. Category: Signaling pathways. CAS No. 2021179-11-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-135660. | |
| MMAF | Monomethyl auristatin F (MMAF) is a synthetic antineoplastic agent. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. In International Nonproprietary Names for MMAF-antibody-conjugates, the name mafodotin refers to MMAF plus its attachment structure to the antibody. Uses: Adcs cytotoxin. Synonyms: Monomethylauristatin F; Monomethyl Auristatin F; N-Methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine; Monomethylauristatin Phenylalanine; L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-; ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine. Grade: ≥98% by HPLC. CAS No. 745017-94-1. Molecular formula: C39H65N5O8. Mole weight: 731.48. | |
| MMAF | MMAF (Monomethylauristatin F) is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF (Monomethylauristatin F) is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as vorsetuzumab mafodotin and SGN-CD19A[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Monomethylauristatin F. CAS No. 745017-94-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-15579. | |
| MMAF hydrochloride | MMAF (Monomethylauristatin F) hydrochloride is a potent tubulin polymerization inhibitor and is used as a antitumor agent. MMAF hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Monomethylauristatin F hydrochloride. CAS No. 1415246-68-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-15579A. | |
| MMAF Hydrochloride | MMAF Hydrochloride, a synthetic antineoplastic agent, is a tubulin polymerization inhibitor that inhibits cell division by blocking the polymerization of tubulin. It is part of some experimental anti-cancer antibody-drug conjugates such as vorsetuzumab mafodotin and SGN-CD19A. Uses: Adcs cytotoxin. Synonyms: Monomethylauristatin F Hydrochloride; Monomethyl Auristatin F Hydrochloride; N-Methyl-L-valyl-L-valyl-(3R,4S,5S)-3-methoxy-5-methyl-4-(methylamino)heptanoyl-(αR,βR,2S)-β-methoxy-α-methyl-2-pyrrolidinepropanoyl-L-phenylalanine Hydrochloride; Monomethylauristatin Phenylalanine Hydrochloride; L-Valinamide, N-methyl-L-valyl-N-[(1S,2R)-4-[(2S)-2-[(1R,2R)-3-[[(1S)-1-carboxy-2-phenylethyl]amino]-1-methoxy-2-methyl-3-oxopropyl]-1-pyrrolidinyl]-2-methoxy-1-[(1S)-1-methylpropyl]-4-oxobutyl]-N-methyl-, Hydrochloride (1:1); ((2R,3R)-3-((S)-1-((3R,4S,5S)-4-((S)-N,3-dimethyl-2-((S)-3-methyl-2-(methylamino)butanamido)butanamido)-3-methoxy-5-methylheptanoyl)pyrrolidin-2-yl)-3-methoxy-2-methylpropanoyl)-L-phenylalanine Hydrochloride. Grade: >98%. CAS No. 1415246-68-2. Molecular formula: C39H66ClN5O8. Mole weight: 768.42. | |
| MMAF intermediate 2 | MMAF intermediate 2 is an intermediate for the synthesis of MMAF (HY-15579). MMAF (Monomethylauristatin F) is a potent inhibitor of tubulin polymerization and the cytotoxic (ADC Cytotoxin) component of classic antibody drug conjugates (ADCs), such as Vorsetuzumab mafodotin and SGN-CD19A[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 864238-20-0. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-79254. | |
| MMAF-OMe | MMAF-Ome, an antitubulin agent, is also an ADC cytotoxin. MMAF-Ome inhibits several tumor cell lines with IC50s of 0.056 nM, 0.166 nM, 0.183 nM, and 0.449 nM for MDAMB435/5T4, MDAMB361DYT2, MDAMB468, and Raji (5T4-) cell lines, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Monomethyl auristatin F methyl ester. CAS No. 863971-12-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-79256. | |
| MMAF sodium | MMAF sodium is a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF sodium is an effective tubulin polymerization inhibitor and is used as an antitumor agent. Synonyms: MMAF (sodium); Monomethylauristatin F sodium. CAS No. 1799706-65-2. Molecular formula: C39H64N5NaO8. Mole weight: 753.94. | |
| m,m'-Ditolylamine | m,m'-Ditolylamine. CAS No. 626-13-1. Molecular formula: C14H15N. Mole weight: 197.27g/mol. IUPAC Name: 3-methyl-N-(3-methylphenyl)aniline. SMILES: CC1=CC(=CC=C1)NC2=CC=CC(=C2)C. InChI: InChI=1S/C14H15N/c1-11-5-3-7-13(9-11)15-14-8-4-6-12(2)10-14/h3-10,15H,1-2H3. |  |
| m-Methoxytopolin | m-Methoxytopolin. Group: Biochemicals. Grades: Highly Purified. CAS No. 75737-39-2. Pack Sizes: 250mg, 500mg, 1g. Molecular Formula: C13H13N5O. US Biological Life Sciences. | Worldwide |
| m-Methyl Atomoxetine Hydrochloride | m-Methyl Atomoxetine Hydrochloride. Group: Biochemicals. Alternative Names: N-Methyl-γ - (3-methylphenoxy) benzenepropanamine Hydrochloride; Atomoxetine Related Compound B Hydrochloride. Grades: Highly Purified. CAS No. 873310-28-2. Pack Sizes: 2.5mg. Molecular Formula: C17H22ClNO, Molecular Weight: 291.82. US Biological Life Sciences. | Worldwide |
| M-METHYL BENZOYL CHLORIDE | M-METHYL BENZOYL CHLORIDE. CAS No. 1711-06-04. Product ID: ACM17110604. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| MMF | MMF. Group: Biochemicals. Grades: Purified. CAS No. 2756-87-8. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| MMG-11 | MMG-11 is a potent and selective human TLR2 antagonist with low cytotoxicity. MMG-11 inhibits both TLR2/1 and TLR2/6 signaling with IC50s of 1.7?μM for Pam3CSK4-induced hTLR2/1 and 5.7?μM for Pam2CSK4-induced hTLR2/6 responses[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 313254-94-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112146. | |
| MMGP1 | MMGP1 is an antifungal peptide which was found to possess potent antifungal activity against C. albicans. | |
| MMH2 | MMH2 is a novel BRD4 molecular glue degrader that functions by recruiting the CUL4 and DCAF16 ligases to the second bromodomain of BRD4 (BRD4BD2)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3079093-15-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156828. | |
| MMI-0100 | MMI-0100 is a cell-permeant peptide inhibitor of mitogen activated protein kinase activated protein kinase II (MK2). MMI-0100 reduces intimal hyperplasia ex vivo and in vivo. MMI-0100 suppresses IL-6 expression without effect on IL-8 expression. MMI-0100 suppresses fibrotic processes such as vein graft disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1039342-24-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P3412. | |
| MMK1 | MMK1 is a potent and selective human formyl peptide receptor like-1 (FPRL-1/FPR2) agonist with EC50s of <2 nM and>10000 nM for FPRL-1 and FPR1, respectively. MMK1 is a potent chemotactic and calcium-mobilizing agonist. MMK1 potently activates phagocytic leukocytes and enhances Pertussis Toxin-sensitive production by human monocytes of proinflammatory cytokines IL-1b and IL-6. MMK1 exerts anxiolytic-like activity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 271246-66-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1117. | |
| MMK 1 | MMK 1 is a potent and selective human formyl peptide receptor FPR2 agonist (EC50 = 1, 2 and > 10 000 nM at mFRP2, hFPR2 and hFPR1 respectively). Some findings showed that the transient rise in intracellular free calcium induced by MMK-1 involves both a release of calcium from intracellular stores and an opening of channels in the plasma membrane. Synonyms: MMK 1; MMK1; MMK-1; (4S)-4-[[(2S)-2-amino-4-methylpentanoyl]amino]-5-[[(2S)-1-[[(2S,3S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(2S)-1-[[(1S)-1-carboxy-3-methylsulfanylpropyl]amino]-3-methyl-1-oxobutan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-(diaminomethylideneamino)-1-oxopentan-2-yl]amino]-1-oxo-3-phenylpropan-2-yl]amino]-3-methyl-1-oxopentan-2-yl]amino]-3-hydroxy-1-oxopropan-2-yl]amino]-5-oxopentanoic acid. CAS No. 271246-66-3. Molecular formula: C75H123N19O18S. Mole weight: 1610.97. | |
| MMK 1 | MMK 1. Group: Biochemicals. Grades: Purified. CAS No. 271246-66-3. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| MMP13-IN-2 | MMP13-IN-2 is a potent, selective and orally active MMP-13 inhibitor. MMP13-IN-2 exhibits excellent potency for MMP-13 (IC50=0.036 nM) and selectivities (greater than 1,500-fold) over MMP-1, 3, 7, 8, 9, 14, and TACE. MMP13-IN-2 has the ability to block the release of collagen from cartilage in vitro. MMP13-IN-2 has the potential for collagenase related disease research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 935759-55-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122624. | |
| MMP-1/MMP-9 Substrate, Fluorogenic | MMP-1/MMP-9 Substrate, Fluorogenic is a fluorogenic substrate for MMP-1 and MMP-9[1].Ex/Em = 340/440 nm. Uses: Scientific research. Category: Signaling pathways. CAS No. 150956-92-6. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P2179. | |
| MMP-2 Inhibitor I | MMP-2 Inhibitor I (OA-Hy) is a potent MMP-2 inhibitor with a Ki of 1.7 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 10335-69-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-112546. | |
| MMP-2 Inhibitor II | MMP-2 Inhibitor II (compound 2) is a selective MMP-2 inhibitor. The Kinetic parameters for MMP inhibition are 2.4 μM (MMP-2), 45 μM (MMP-1), and 379 μM (MMP-7), respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 869577-51-5. Pack Sizes: 1 mg; 5 mg. Product ID: HY-130076. | |
| MMP-2 Inhibitor IV (Bone Resorption Inhibitor, (4'-chlorobiphenyl-4ylsulfonamido) methylenediphosphonic Acid) | A cell-permeable, bisphosphonate derivative that displays nanomolar activity against MMP-2 (IC50=37nM), with good selectivity over MMP-8 (320nM), MMP-9 (>1uM), and MMP-14 (> 1uM). It is shown to inhibit osteoclast activity in a macrophage cell line, J774 (IC50=1.7uM), which is more potent compared with other bisphosphonates such as Alendronate, (IC50=30uM), and Zolendronate (7.8uM), without observable cytotoxicity in HepG2 cells. At 25uM, it abolishes the formation of actin rings, which are functional structures that are typical of resorbing osteoclasts, at activity levels comparable with those of zolendronic acid, inhibits bone resportion in vitro, and demonstrates cytotoxic properties in murine osteoclasts. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| MMP-2/MMP-9-IN-1 | MMP-2/MMP-9-IN-1 is a highly selective, orally active and potent type IV collagenase (MMP-9 and MMP-2) inhibitor with IC50s of 0.24 and 0.31 μM for MMP-9 and MMP-2, respectively. MMP-2/MMP-9-IN-1 is orally active in animal models of tumor growth and metastasis. MMP-2/MMP-9-IN-1 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 193807-58-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116399. | |
| MMP-2/MMP-9 Substrate | MMP-2/MMP-9 Substrate (Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt) is a synthetic chromogenic polypeptide substrate whose core structure mimics the cleavage sites of MMP-2 and MMP-9 (gelatinase A and B) in collagen. After being hydrolyzed by collagenase, MMP-2/MMP-9 Substrate reacts with 4,4'-dithiodipyridine or Ellman's Reagent via its thiol fragment to produce a product with ultraviolet absorption properties[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ac-Pro-Leu-Gly-[(S)-2-mercapto-4-methyl-pentanoyl]-Leu-Gly-OEt. CAS No. 99828-55-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10143. | |
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