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| Product | Description | |
|---|---|---|
| MRTX1133 | MRTX1133 is a noncovalent, potent, and selective alkyne-based KRAS G12D inhibitor. MRTX1133 optimally fills the switch II pocket and extends three substituents to favorably interact with the protein, resulting in an estimated KD against KRAS G12D of 0.2 pM. MRTX1133 prevents SOS1-catalyzed nucleotide exchange and/or formation of the KRAS G12D/GTP/RAF1 complex, thereby inhibiting mutant KRAS-dependent signal transduction. MRTX1133 selectively inhibits KRAS G12D mutant, but not KRAS wild-type, tumor cells. MRTX1133 has single digit nanomolar activity in cellular assays and marked in vivo efficacy in tumor models harboring KRAS G12D mutations[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2621928-55-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-134813. |  |
| MRTX849 | MRTX849 Inhibitor. Uses: Scientific use. Product Category: T8369. CAS No. 2326521-71-3. |  |
| MRX-1024 | MRX-1024 is a proprietary oral formulation of D-methionine with antioxidant and antimucositis activities. D-methionine formulation MRX-1024 may selectively protect the oral mucosa from the toxic effects of chemotherapy and radiation therapy without compromising antitumor activity. D-methionine may be converted into the L- isomer in vivo, particlualry in instances of L-methionine deprivation, both isomers have antioxidant activity which may be due, in part, to their sulfur moieties and chelating properties. L-methionine, an essential amino acid, also may help to maintain the ratio of reduced glutathione to oxidized glutathione in cells undergoing oxidative stress and may provide a source of L-cysteine for glutathione synthesis. Synonyms: Methionine; D-Methionine; (R)-Methionine; NSC 45689; S-Methyl-D-homocysteine; H-D-Met-OH; (R)-2-amino-4-(methylthio)butanoic acid; D-2-Amino-4-(methylthio)butyric acid. Grade: ≥97%. CAS No. 348-67-4. Molecular formula: C5H11NO2S. Mole weight: 149.21. |  |
| MRX-2843 | MRX-2843 (UNC2371) is an orally active, ATP-competitive dual MERTK and FLT3 tyrosine kinases inhibitor (TKI) with enzymatic IC50s of 1.3 nM for MERTK and 0.64 nM for FLT3, respectively[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UNC2371. CAS No. 1429882-07-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101549. | |
| MRX-2843 | MRX-2843, also known as UNC2371, is a potent and orally active MERTK and FLT3 inhibitor. MRX-2843 overcomes resistance-conferring FLT3 mutations in acute myeloid leukemia. MRX-2843 in combination with an irreversible EGFR TKI as a novel strategy for treatment of patients with wtEGFR NSCLC. MRX-2843 treatment induces apoptosis and inhibits colony formation in AML cell lines and primary patient samples expressing MERTK and/or FLT3-ITD, with a wide therapeutic window compared with that of normal human cord blood cells. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MRX-2843; MRX 2843; MRX2843; UNC2371; UNC-2371; UNC 2371; UNC2371A; UNC-2371A; UNC 2371A. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1429882-07-4. Molecular formula: C29H40N6O. Mole weight: 488.68. Purity: >95%. IUPACName: (1r,4r)-4-(2-((2-cyclopropylethyl)amino)-5-(4-((4-methylpiperazin-1-yl)methyl)phenyl)-7H-pyrrolo[2,3-d]pyrimidin-7-yl)cyclohexanol. Canonical SMILES: O[C@H]1CC[C@H](N2C=C(C3=CC=C(CN4CCN(C)CC4)C=C3)C5=CN=C(NCCC6CC6)N=C52)CC1. Product ID: ACM1429882074. Alfa Chemistry ISO 9001:2015 Certified. |  |
| MS0015203 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| MS012 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MS023 | MS023 is a potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1831110-54-3. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19615. | |
| MS023 dihydrochloride | MS023 dihydrochloride is a potent, selective, and cell-active inhibitor of human type I protein arginine methyltransferases (PRMTs) inhibitor, with IC50s of 30, 119, 83, 4 and 5 nM for PRMT1, PRMT3, PRMT4, PRMT6, and PRMT8, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1992047-64-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19615B. | |
| MS023 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MS049 hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MS-1020 | Selective JAK3 inhibitor. Blocks STAT signaling. Inducer of apoptosis via down-regulation of anti-apoptotic gene expression. Group: Biochemicals. Alternative Names: 1-Hydroxy-N-(2-(5-hydroxy-1H-indol-3-yl)ethyl)-2-naphthamide. Grades: Highly Purified. CAS No. 1255516-86-9. Pack Sizes: 1mg. Molecular Formula: C21H18N2O3. US Biological Life Sciences. |  Worldwide |
| MS-1020 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MS15 | MS15 is a potent and selective AKT PROTAC degrader. MS15 inhibits the AKT1, -2, and -3 activities, with IC 50 values of 798 nM, 90 nM, and 544 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3035638-40-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-151613. | |
| MS170 | MS170 is a potent and selective PROTAC AKT degrader. MS170 depletes cellular total AKT (T-AKT) with the DC 50 value of 32 nM. MS170 binds to AKT1, AKT2, and AKT3 with K d s of 1.3 nM, 77 nM, and 6.5 nM, respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2376136-61-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-145282. | |
| MS177 | MS177 is an effective and fast-acting EZH2 degrader. MS177 is a PROTAC that consists of a CRBN ligand, linker, and a potent enzymatic EZH2 inhibitor C24 (C24 IC50): 12 nM). MS177 effectively depletes both canonical EZH2-PRC2 and noncanonical EZH2-cMyc complexes. MS177 induces leukaemia cell growth inhibition, apoptosis and cell cycle progression arrest[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225938-86-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148333. | |
| MS1943 | MS1943 is an orally active, PROTAC-based, selective degrader of EZH2 that effectively reduces EZH2 levels in cells. MS1943 has anticancer activity and exhibits cytotoxic effects in a variety of TNBC cells while sparing normal cells. In addition, MS1943 maintains high potency (IC50=120 nM) in inhibiting EZH2 methyltransferase activity and is highly selective for EZH2. (Structure Note: RED, EZH2 ligand (HY-148458); Blue, Hyt (HY-W001578))[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225938-17-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-133129. | |
| MS21 | MS21, a novel degrader of AKT , selectively inhibits the growth of PI3K/PTEN pathway-mutant cancers with wild-type KRAS and BRAF. Uses: Scientific research. Group: Signaling pathways. CAS No. 2376137-05-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-141807. | |
| MS 245 oxalate | MS 245 oxalate. Group: Biochemicals. Grades: Purified. CAS No. 275363-58-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MS-275 | HDAC 1 inhibitor. Antitumor compound. Antiproliferative. TGF-beta type II receptor inducer. Apoptosis inducer. Anti-inflammatory. Angiogenesis inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 209783-80-2. Pack Sizes: 1mg, 5mg, 25mg. Molecular Formula: C21H20N4O3. US Biological Life Sciences. | Worldwide |
| MS-275 (Entinostat, SNDX-275) | Preferentially inhibits HDAC1 (IC50=300 nM) over HDAC3 (IC50=8uM). Has no inhibitory activity towards HDAC8 (IC50>100uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 209783-80-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| MS-282a | MS-282a is produced by the strain of Streptomyces tauricus. It inhibits calmodulin-dependent MLCK with an IC50 of 3.8 μmol/L. It has anti-gram-positive bacteria activity. Synonyms: MS-282-A. CAS No. 152158-04-8. Molecular formula: C37H65NO7. Mole weight: 635.91. | |
| MS-282b | MS-282b is produced by the strain of Streptomyces tauricus. It inhibits calmodulin-dependent MLCK with an IC50 of 5.2 μmol/L. It has anti-gram-positive bacteria activity. Synonyms: MS-282-B. CAS No. 152759-50-7. Molecular formula: C37H65NO7. Mole weight: 635.91. | |
| MS37452 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MS39 | MS39 (compound 6) is a PROTAC targeting EGFR. MS39 is composed of PROTAC target protein ligand N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-(3-(piperazin-1-yl)propoxy)quinazolin-4-amine (HY-W109039) (red part), E3 ligase ligand (S,R,S)-AHPC (HY-125845) (blue part) and PROTAC Linker Undecanedioic acid (HY-W014125) (black part), among which the conjugate of E3 ubiquitin ligase ligand + Linker is (S,R,S)-AHPC-CO-C9-acid (HY-139345). MS39 reduces the expression of EGFR and downstream signaling in HCC-827 and H3255 cells. MS39 inhibits the proliferation of H3255 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2675490-92-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157581. | |
| MS4078 | MS4078 is an anaplastic lymphoma kinase (ALK) PROTAC (degrader) based on Cereblon ligand, with a Kd of 19?nM for binding affinity to ALK[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2229036-62-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112155. | |
| MS41 | MS41 is a selective eleven-nineteen leukemia (ENL) PROTAC degrader, with DC 50 s of 3.50 nM (MV4;11), 2.84 nM (SEMK2), 3.03 nM (Jurkat), and 26.58 nM (KASUMI1), respectively. MS41 effectively inhibits the growth of ENL-dependent leukemia cells, induces G1 cell cycle arrest and increases apoptosis. MS41 reduces the chromatin occupancy of ENL-associated transcription elongation machinery, and suppresses oncogenic gene expression and leukemia progression. Red: ENL ligand (HY-169094). Black: linker (HY-W105744). Blue: VHL ligand (HY-112078) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2768610-97-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-169093. | |
| MS432 | MS432 is a first-in-class and highly selective PD0325901-based von Hippel-Lindau-recruiting PROTAC degrader for MEK1 and MEK2. MS432 displays good plasma exposure in mice, exhibiting DC50 values of 31 nM and 17 nM for MEK1, MEK2 in HT29 cells respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2672512-44-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130602. | |
| MS4322 | MS4322 (YS43-22) is a specific PRMT5 PROTAC degrader. MS4322 reduces the PRMT5 protein level with a DC50 of 1.1 ?M in MCF-7 cells. MS4322 inhibits the methyltransferase activity of PRMT5 with an IC50 of 18 nM. MS4322 promotes ubiquitination and degradation of PRMT5. MS4322 can be used for the research of breast cancer, lung cancer, and hepatocellular cancer. (Pink: PRMT5 ligand (HY-173092); Blue: E3 ligase ligand HY-112078); Black: linker (HY-124780); E3+linker (HY-173093 ))[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: YS43-22. CAS No. 2375432-47-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-141877. | |
| MS438 | MS438 is a potent thyrotropin receptor ( TSHR ) agonist with an EC 50 of 53 nM. MS438 binds to the serpentine portion of the TSHR. MS438 induces T4 secretion in mice [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 512840-45-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-114918. | |
| MS-444 | MS-444, originally isolated from Micromonospora sp. KY7123, is a myosin light chain kinase (MLCK) inhibitor. Synonyms: 5,8-Dihydroxy-3-methyl-4-(9H)-naphtho(2,3-c)furanone; MS 444; 5,8-dihydroxy-3-methyl-9H-benzo[f][2]benzofuran-4-one. CAS No. 150045-18-4. Molecular formula: C13H10O4. Mole weight: 230.22. | |
| MS-444 | MS-444 inhibits the activity of purified smooth muscle myosin light chain kinase (MLCK) with an IC50 value of 10 ?M. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BE-34776. CAS No. 150045-18-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100685. | |
| MS67 | MS67 is a potent and selective WD40 repeat domain protein 5 (WDR5) degrader with a Kd of 63 nM. MS67 is inactive against other protein methyltransferases, kinases, GPCRs, ion channels, and transporters. MS67 shows potent acticancer effects[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407452-77-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141796. | |
| MS-681a | MS-681a, originally isolated from Myrothecium sp. KY6568, is a myosin light chain kinase (MLCK) inhibitor (IC50=0.11 μmol/L). CAS No. 173485-72-8. Molecular formula: C61H91N13O9. Mole weight: 1150.45. | |
| MS8709 | MS8709 (compound 10), a potential anticancer therapeutic, is a first-in-class G9a/GLP PROTAC degrader. MS8709 is based on G9a/GLP inhibitor UNC0642 and recruits the von Hippel Lindau (VHL) E3 ligase (Red: G9a/GLP inhibitor UNC0642; Blue: VHL ligand; Black: linker)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3060730-06-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-162362. | |
| MS934 | MS934 is a novel improved VHL-recruiting MEK 1/2 PROTAC degrader. MS934 also degrades CRAF. MS934 can be used for the research of variety of human cancers, such as melanoma, nonsmall cell lung cancer (NSCLC), colorectal cancer, primary brain tumors, and hepatocellular carcinoma (Pink: Target protein ligand (HY-168288); Black: linker (HY-168289); Blue: E3 ligase ligand (HY-112078))[1][2][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2756323-15-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153863. | |
| MSA-2 | MSA-2 Inhibitor. Uses: Scientific use. Product Category: T8798. CAS No. 129425-81-6. | |
| MSA-2 | MSA-2, a potent and orally available non-nucleotide STING agonist, is bound to STING as a noncovalent dimer with nanomolar affinity. MSA-2 shows EC50s of 8.3 and 24 ?M for human STING isoforms WT and HAQ, respectively. MSA-2 stimulates interferon-? secretion in tumors, induces tumor regression with durable antitumor immunity, and synergizes with anti-PD-1 in syngeneic mouse tumor models[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 129425-81-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-136927. | |
| MSAB | MSAB is a potent and selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin and promotes its degradation, and specifically downregulates Wnt/β-catenin target genes. MSAB exhibits potent anti-tumor effects selectively on Wnt-dependent cancer cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 173436-66-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120697. | |
| MSAB | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| m-Salicylic Acid | m-Salicylic Acid is widely used in organic synthesis. It is also an important active metabolite of aspirin (A187780). Group: Biochemicals. Alternative Names: 3-Hydroxybenzoic Acid; 3-Carboxyphenol; NSC 55746; m-Carboxyphenol; m-Hydroxybenzoic Acid. Grades: Highly Purified. CAS No. 99-06-9. Pack Sizes: 10g. US Biological Life Sciences. | Worldwide |
| MSBN | MSBN is a highly selective fluorogenic probe for thiols. MSBN can be used to image thiols in live cells selectively and specifically label protein thiols with a signal to determine various reversible protein thiol modifications [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 135980-66-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119493. | |
| MSC1094308 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| MSC1094308 | MSC1094308 is a non-competitive and reversible VPS4B/p97 (VCP) (I/II type AAA ATPase) allosteric inhibitor, with IC50 values of 0.71 ?M and 7.2 ?M for VPS4B and p97, respectively[1]. MSC1094308 inhibits the D2 ATPase activity by binding to a agentable hotspot of p97. MSC1094308 can be used in study of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2219320-08-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123872. | |
| MSC2530818 | MSC2530818 is a potent, selective and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8. Uses: Scientific research. Group: Signaling pathways. CAS No. 1883423-59-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101611. | |
| MSC-4381 | MSC-4381 (MCT4-IN-1) is an orally active and selective monocarboxylate transporter 4 (MCT4/SLC16A3) inhibitor with an IC 50 of 77 nM and a K i of 11 nM. MSC-4381 targets to the cytosolic domain of MCT4. MSC-4381 results in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells. MSC-4381 has the potential for MCT4 transporter inhibition research [1]. MSC-4381 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MCT4-IN-1. CAS No. 2445185-57-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132301. | |
| m-Scrobiculin | m-Scrobiculin. Synonyms: Scrobiculin. CAS No. 15081-04-6. Molecular formula: C22H26O8. Mole weight: 418.44. | |
| MSD-819 | MSD-819 is extracted from Streptomycess ambofaciens. It has anti-gram-positive and anti-gram-negative bacteria activity. Synonyms: 2-Quinoxalinecarboxylicacid, 6-chloro-, 1,4-dioxide; 3-Carboxy-7-chloro-1-oxoquinoxalin-1-ium-4(1H)-olate. CAS No. 22587-15-1. Molecular formula: C9H5ClN2O4. Mole weight: 240.60. | |
| MSD-92 | It is originally isolated from Actinomyces sp. MSD-92 has anti-gram-positive and anti-gram-negative activity, and the MIC of it against Escherichia coli was 2 μg/mL. Synonyms: 2-Methylfervenulone; BRN 0540815; 2,8-Dihydro-2,6,8-trimethylpyrimido(5,4-e)-as-triazine-3,5,7-trione. CAS No. 22712-32-9. Molecular formula: C8H9N5O3. Mole weight: 223.19. | |
| MSDC 0160 | MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has the potential for Alzheimers disease [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Mitoglitazone; CAY10415. CAS No. 146062-49-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100550. | |
| Msdh-c | Msdh-c. Uses: Designed for use in research and industrial production. Additional or Alternative Names: D-ERYTHRO-1-METHYLTHIOHYDROCERAMIDE;(2R,3R)-(2-N-LAUROYL)-AMINO-1-METHYLTHIO-3-HYDROXYNONAN;MSDH-C. Product Category: Heterocyclic Organic Compound. Appearance: White to off-white powder. CAS No. 144474-37-3. Molecular formula: C22H45NO2S. Mole weight: 387.66. Product ID: ACM144474373. Alfa Chemistry ISO 9001:2015 Certified. Categories: MS Dhoni. | |
| MSG606 | MSG606 is a selective MC1R (melanocortin 1 receptor) antagonist and can be used for the research of neuroprotective effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1416983-77-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1726. | |
| MSG 606 | MSG 606 is a potent human MC1 receptor antagonist (IC50 = 17 nM), and also partial agonist at human MC3 and MC5 receptors (EC50= 59 and 1300 nM, respectively). Synonyms: MSG 606; MSG606; MSG-606. CAS No. 1416983-77-1. Molecular formula: C62H82N20O13S. Mole weight: 1347.51. | |
| MSI-1436 | MSI-1436 is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B) , with an IC 50 of appr 1 μM, 200-fold preference over TCPTP (IC 50 , 224 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trodusquemine; Aminosterol-1436. CAS No. 186139-09-3. Pack Sizes: 500 μg. Product ID: HY-12219. | |
| MSI-1436 lactate | MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B ( PTP1B ), with an IC 50 of 1 μM, 200-fold preference over TCPTP ( IC 50 of 224 μM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: Trodusquemine lactate; Aminosterol-1436 lactate. CAS No. 1309370-86-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12219A. | |
| MSI-594 | MSI-594 is a highly active AMP with a broad-spectrum of activities against bacteria, fungi, and virus. | |
| mSIRK | mSIRK (G-Protein ?? Binding Peptide) is an cell-permeable activator of ERK1/2, with EC50 of 2.5-5 ?M. mSIRK disrupts the interaction between ? and ?? subunits and promotes ? subunit dissociation without stimulating nucleotide exchange[1]. Uses: Scientific research. Group: Peptides. CAS No. 593267-11-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P5985. | |
| mSiTrz | mSiTrz. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 2-Phenyl-4,6-bis(3-(triphenylsilyl)phenyl)-1,3,5-triazine. Product Category: Organic Light Emitting Diode (OLED). CAS No. 2252416-90-1. Molecular formula: C57H43N3Si2. Mole weight: 826.14 g/mol. Product ID: ACM2252416901. Alfa Chemistry ISO 9001:2015 Certified. Categories: Mistrzejowice. | |
| Msk-195 | Msk-195. Uses: Designed for use in research and industrial production. Additional or Alternative Names: SureCN93984, CTK8E9625, MSK-195, 289902-82-5. Product Category: Heterocyclic Organic Compound. Appearance: White solid. CAS No. 289902-82-5. Molecular formula: C28H40N2O5. Mole weight: 484.6. Purity: 0.96. IUPACName: [2-[[[2-[4-(2-aminoethoxy)-3-methoxyphenyl]acetyl]amino]methyl]-3-(3,4-dimethylphenyl)propyl] 2,2-dimethylpropanoate. Product ID: ACM289902825. Alfa Chemistry ISO 9001:2015 Certified. | |
| MSK1, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| MSK2, active, GST tagged from mouse | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| MSM - Methyl Sulfonyl Methane | MSM - Methyl Sulfonyl Methane. |  CA, FL & NJ |
| MSN-125 | MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC50 of 4 ?M. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1592908-16-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120079. | |
| MSN-50 | MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1592908-75-2. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118948. | |
| MSNBA | MSNBA is a specific inhibitor of GLUT5 fructose transport in proteoliposomes. MSNBA competitively inhibits GLUT5 fructose uptake with a K I of 3.2±0.4 μM in MCF7 cells [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 852702-51-3. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-W179181. | |
| Msop | Msop. Uses: Designed for use in research and industrial production. Additional or Alternative Names: MSOP;(RS)-ALPHA-METHYLSERINE-O-PHOSPHATE;(R,S)-a-Methylserine-O-phosphate. Product Category: Heterocyclic Organic Compound. CAS No. 66515-29-5. Molecular formula: C4H10NO6P. Mole weight: 199.1. Product ID: ACM66515295. Alfa Chemistry ISO 9001:2015 Certified. | |
| MSOP | MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent K D of 51 μM for the L-AP4-sensitive presynaptic mGluR. Uses: Scientific research. Group: Signaling pathways. CAS No. 66515-29-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101226. | |
| MSOP | MSOP. Group: Biochemicals. Grades: Purified. CAS No. 66515-29-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| MSP-3 | MSP-3 is a potent TRPV1 agonist, with an EC 50 of 0.87 μM. MSP-3 exhibits neuroprotective and antinociceptive effects [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1820968-63-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118785. | |
| MSP-3 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
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