A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
MSA-2 is a STING agonist that exhibits antitumor effects in animal studies. Alternative Names: MSA 2; MSA2; 4-(5,6-dimethoxybenzo[b]thiophen-2-yl)-4-oxobutanoic acid. Grades: 98% by HPLC. CAS No. 129425-81-6. Molecular formula: C14H14O5S. Mole weight: 294.32.
MSAB
MSAB is a potent and selective inhibitor of Wnt/β-catenin signaling. MSAB binds to β-catenin and promotes its degradation, and specifically downregulates Wnt/β-catenin target genes. MSAB exhibits potent anti-tumor effects selectively on Wnt-dependent cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 173436-66-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120697.
m-Salicylic Acid
m-Salicylic Acid is widely used in organic synthesis. It is also an important active metabolite of aspirin (A187780). Group: Biochemicals. Alternative Names: 3-Hydroxybenzoic Acid; 3-Carboxyphenol; NSC 55746; m-Carboxyphenol; m-Hydroxybenzoic Acid. Grades: Highly Purified. CAS No. 99-06-9. Pack Sizes: 10g. US Biological Life Sciences.
Worldwide
MSC1094308
MSC1094308 is a non-competitive and reversible VPS4B/p97 (VCP) (I/II type AAA ATPase) allosteric inhibitor, with IC50 values of 0.71 μM and 7.2 μM for VPS4B and p97, respectively[1]. MSC1094308 inhibits the D2 ATPase activity by binding to a agentable hotspot of p97. MSC1094308 can be used in study of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2219320-08-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123872.
MSC-1186
MSC-1186, a chemical probe, is a highly selective pan-SRPK inhibitor. MSC-1186 has activity for SRPK1, SRPK2 and SRPK3 with IC50 values of 2.7 nM, 81 nM and 0.6 nM, respectively. MSC-1186 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2871698-23-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148518.
MSC2504877
MSC2504877 (M2912) is a potent and orally active tankyrase inhibitor with IC50s of 0.0007, 0.0008, 0.54 μM for TNKS, TNKS2, PARP1, respectively. MSC2504877 increases the expression of AXIN2 and TNKS protein levels and decreases β-catenin levels. MSC2504877 shows anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: M2912. CAS No. 1460286-21-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123851.
MSC2530818
MSC2530818 is a specific and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8. Alternative Names: MSC2530818; MSC-2530818; MSC 2530818. [(2S)-2-(4-chlorophenyl)pyrrolidin-1-yl]-(3-methyl-2H-pyrazolo[3,4-b]pyridin-5-yl)methanone; SCHEMBL17514257; s8387; AKOS032946259. CAS No. 1883423-59-3. Molecular formula: C18H17ClN4O. Mole weight: 340.81.
MSC2530818
MSC2530818 is a potent, selective and orally available CDK8 inhibitor with an IC50 of 2.6 nM for CDK8. Uses: Scientific research. Category: Signaling pathways. CAS No. 1883423-59-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101611.
MSC-4106
MSC-4106 is an orally active and potent inhibitor of YAP/TAZ-TEAD. MSC-4106 inhibits TEAD1 or TEAD3 auto-palmitoylation and shows inhibitory effect on NCI-H226 tumor xenograft model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2738542-58-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147208.
MSC-4381
MSC-4381 (MCT4-IN-1), a chemical probe, is an orally active and selective monocarboxylate transporter 4 (MCT4/SLC16A3) inhibitor with an IC50 of 77 nM and a Ki of 11 nM. MSC-4381 targets to the cytosolic domain of MCT4. MSC-4381 results in lactate efflux inhibition and reduction of cellular viability in MCT4 high expressing cells. MSC-4381 has the potential for MCT4 transporter inhibition research[1]. MSC-4381 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MCT4-IN-1. CAS No. 2445185-57-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132301.
m-Scrobiculin
m-Scrobiculin. Alternative Names: Scrobiculin. CAS No. 15081-04-6. Molecular formula: C22H26O8. Mole weight: 418.44.
MSD-819
MSD-819 is extracted from Streptomycess ambofaciens. It has anti-gram-positive and anti-gram-negative bacteria activity. Alternative Names: 2-Quinoxalinecarboxylicacid, 6-chloro-, 1,4-dioxide; 3-Carboxy-7-chloro-1-oxoquinoxalin-1-ium-4(1H)-olate. CAS No. 22587-15-1. Molecular formula: C9H5ClN2O4. Mole weight: 240.60.
MSD-92
It is originally isolated from Actinomyces sp. MSD-92 has anti-gram-positive and anti-gram-negative activity, and the MIC of it against Escherichia coli was 2 μg/mL. Alternative Names: 2-Methylfervenulone; BRN 0540815; 2,8-Dihydro-2,6,8-trimethylpyrimido(5,4-e)-as-triazine-3,5,7-trione. CAS No. 22712-32-9. Molecular formula: C8H9N5O3. Mole weight: 223.19.
MSDC 0160
MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC 0160 has the potential for Alzheimers disease[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mitoglitazone; CAY10415. CAS No. 146062-49-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100550.
MSDC-0160
MSDC-0160 reduces resistance in the insulin/IGF-1 signaling pathway and restores IGF-1-induced Akt and GSK-3 phosphorylation. Alternative Names: Mitoglitazone; CAY10415; 5-[[4-[2-(5-Ethyl-2-pyridinyl)-2-oxoethoxy]phenyl]methyl]-2,4-thiazolidinedione; Pioglitazone Ketone; 5-(4-(2-(5-ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione; 5-{4-[2-(5-ethylpyridin-2-yl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione. Grades: >98%. CAS No. 146062-49-9. Molecular formula: C19H18N2O4S. Mole weight: 370.42.
MSDC-0602
MSDC-0602 is an insulin sensitizer that has the potential to treat diabetes and other inflammatory diseases. It exhibits low affinity for binding and activation of PPARγ. Alternative Names: MSDC-0602; MSDC0602; MSDC 0602; 5-{4-[2-(3-Methoxyphenyl)-2-oxoethoxy]benzyl}-1,3-thiazolidine-2,4-dione; 2,4-Thiazolidinedione, 5-[[4-[2-(3-methoxyphenyl)-2-oxoethoxy]phenyl]methyl]-. CAS No. 1133819-87-0. Molecular formula: C19H17NO5S. Mole weight: 371.407.
MSDH
MSDH is a key enzyme in the biosynthesis of Coenzyme Q10, a vital component in cellular energy production. Inhibition of MSDH can be a potential target for the treatment of certain cancers and neurodegenerative diseases. Alternative Names: (S)-O-methyl-serine dodecylamide hydrochloride; N-Dodecyl-O-methyl-L-serinamide hydrochloride (1:1); Propanamide, 2-amino-N-dodecyl-3-methoxy-, (2S)-, hydrochloride (1:1). CAS No. 2074614-60-9. Molecular formula: C16H35ClN2O2. Mole weight: 322.91.
MSG606
MSG606 is a selective melanocortin 1 receptor (MC1R) antagonist. MSG606 can abolish the neuroprotective effects of BMS-470539 (HY-15616) (MC1R agonist). MSG606 can inhibit cancer cell proliferation and transition from the G1 to the S phase. MSG606 can delay pain hypersensitivity and reduce cholesterol levels. MSG606 can be used for the researches of cancer, inflammation, neurological and metabolic disease, such as breast cancer and subarachnoid hemorrhage (SAH)[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1416983-77-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1726.
MSG 606
MSG 606 is a potent human MC1 receptor antagonist (IC50 = 17 nM), and also partial agonist at human MC3 and MC5 receptors (EC50= 59 and 1300 nM, respectively). Alternative Names: MSG 606; MSG606; MSG-606. CAS No. 1416983-77-1. Molecular formula: C62H82N20O13S. Mole weight: 1347.51.
MS-H220-V3 LCD Digital Heating Magnetic Stirring Bath
High borosilicate glass liner, resistant to sudden changes from hot to cold without breaking, transparent glass window for monitoring reaction product changes; stainless steel base, rust-resistant, easy to clean; high-temperature. resistant protective outer shell to prevent direct contact with hot glass and burns. Dual-use stirring bath for water and oil, with secondary stirring in the bath pot. The stirring of the bath liquid simultaneously stirs the liquid sample in the flask, ensuring uniform heating of both bath liquid and sample. Safety lock to prevent accidental changes in operational status. Buzzer: A beep beep beep alert sounds when the countdown timer function ends. Button tone. Features a timer function with a range of 1 min to 99h59min. It stops heating when the countdown ends but continues stirring to prevent heat damage to the sample. Touch buttons with audible prompts. Working status indicator light: Green during operation, flashing green before reaching set temperature; alarm red. Reversible function. Protection features: dry burning protection, overcurrent protection, ground fault protection, and over temperature protection. Residual heat warning function. When the plate temperature is above 50°C , heating is turned off, and the screen flashes HOT as a reminder of the high temperature even after the power is off. Two independent safety circuits continuously monitor
MS-H220-V5 LCD Digital Heating Magnetic Stirring Bath
High borosilicate glass liner, resistant to sudden changes from hot to cold without breaking, transparent glass window for monitoring reaction product changes; stainless steel base, rust-resistant, easy to clean; high-temperature. resistant protective outer shell to prevent direct contact with hot glass and burns. Dual-use stirring bath for water and oil, with secondary stirring in the bath pot. The stirring of the bath liquid simultaneously stirs the liquid sample in the flask, ensuring uniform heating of both bath liquid and sample. Safety lock to prevent accidental changes in operational status. Buzzer: A beep beep beep alert sounds when the countdown timer function ends. Button tone. Features a timer function with a range of 1 min to 99h59min. It stops heating when the countdown ends but continues stirring to prevent heat damage to the sample. Touch buttons with audible prompts. Working status indicator light: Green during operation, flashing green before reaching set temperature; alarm red. Reversible function. Protection features: dry burning protection, overcurrent protection, ground fault protection, and over temperature protection. Residual heat warning function. When the plate temperature is above 50°C , heating is turned off, and the screen flashes HOT as a reminder of the high temperature even after the power is off. Two independent safety circuits continuously monitor
MS-H280-Pro LED Digital Magnetic Hotplate Stirrer
Digital temperature control with maximum temperature up to 280°C. Digital speed control with maximum speed up to 1500rpm. Stainless steel with ceramic coating work plate provides high chemical resistant performance. External temperature control is possible by connecting temperature sensor(PT1000) with an accuracy at ±0.2°C. LED display shows temperature and stirring speed. "HOT" warning flashes if work plate temperature is above 50°C. Uses: Equipment for sample preparation. Group: Laboratory equipment. Product ID: 8030101212. Categories: Magnetic Hotplate Stirrer.
MS-H340-S4
Independent heating and stirring control for each position. LCD display shows real-time temperature and speed. PID controller ensures a precise and stable heating process (maximum temperature up to 340°C). Brushless DC motor is quiet, reliable & maintenance free, and provides more powerful speed control. External temperature sensor (PT1000) with accuracy 0.2°C. Overheating protection temperature at 420°C. Stainless steel work plate with ceramic coating provides good chemical resistance. Wide variety of accessories available to choose from. Categories: Labooratory Mixers, Shakers & Stirrers.
MSH, N(alpha)-chlorotriazinylaminofluorescein-1-Ser-4-Nle-7-Phe-alpha-. CAS No. 97475-26-8. Product ID: ACM97475268. Alfa Chemistry - ISO 9001:32057 Certified.
MS-H-ProA LCD Digital Magnetic Hotplate Stirrer
DC brushless motor free of maintenance and spark, and with long service life. Digital temperature control up to 340°C. Digital speed control up to 1500rpm. Maximum stirring quantity of H2O is 20L. Safety circuits provide overheating protection. "HOT" warning flashes if plate temperature is above 50°C even when hotplate is turned off. External temperature control is possible by connecting the temperature sensor(PT 1000)with accuracy at ±0.2°C. Work plate with ceramic coating provides good chemical-resistantperformance. Remote function provides PC control and data transmission. Wide variety of accessories available to choose. Uses: Equipment for sample preparation. Group: Laboratory equipment. Product ID: 8060221110. Categories: Magnetic Hotplate Stirrer.
MS-H-S
Brushless DC motor is maintenance free and explosion-proof. Digital temperature control up to 340°C. Digital speed control up to 1500rpm. Maximum stirring quantity of H2O is 20L. Safety circuits provide overheating protection. "HOT" warning flashes if plate temperature is above 50°C even when hotplate is turned off. Work plate with ceramic coating provides good chemical-resistantperformance. Wide variety of accessories available to choose. Categories: Labooratory Mixers, Shakers & Stirrers.
MSI-1436 lactate
MSI-1436 lactate is a selective, non-competitive inhibitor of the enzyme protein-tyrosine phosphatase 1B (PTP1B), with an IC50 of 1 μM, 200-fold preference over TCPTP (IC50 of 224 μM). Uses: Scientific research. Category: Signaling pathways. Alternative Names: Trodusquemine lactate; Aminosterol-1436 lactate. CAS No. 1309370-86-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12219A.
MSI-594
MSI-594 is a highly active AMP with a broad-spectrum of activities against bacteria, fungi, and virus.
MS-L6
MS-L6 is a potent inhibitor of oxidative phosphorylation (OXPHOS) that can acts as electron transport chain complexes I (ETC-I) combining inhibition of NADH oxidation and uncoupling effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 63498-32-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158421.
MSM - Methyl Sulfonyl Methane
MSM - Methyl Sulfonyl Methane.
CA, FL & NJ
MSN-125
MSN-125 is a potent Bax and Bak oligomerization inhibitor. MSN-125 prevents mitochondrial outer membrane permeabilization (MOMP) with an IC50 of 4 μM. MSN-125 potently inhibits Bax/Bak-mediated apoptosis in HCT-116, BMK Cells, and primary cortical neurons, protects primary neurons against glutamate excitotoxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1592908-16-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-120079.
MSN-50
MSN-50 is a Bax and Bak oligomerization inhibitor. MSN-50 efficiently inhibits liposome permeabilization, prevents genotoxic cell death and promotes neuroprotection[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1592908-75-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-118948.
MSNBA
MSNBA is a potent and selective GLUT5 fructose transport inhibitor with an IC50 of 0.10?mM. MSNBA does not affect the transport activity of human GLUT1, GLUT2, GLUT3, GLUT4 or bacterial GlcPSe. MSNBA competitively inhibits GLUT5 fructose uptake with a Ki of 3.2 μM in MCF7 cells. MSNBA can be used for the study of cancer or diabetes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 852702-51-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-W179181.
MSOP
MSOP. Group: Biochemicals. Grades: Purified. CAS No. 66515-29-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
MSOP
MSOP is a selective group III metabotropic glutamate receptor antagonist with apparent KD of 51 μM for the L-AP4-sensitive presynaptic mGluR. Uses: Scientific research. Category: Signaling pathways. CAS No. 66515-29-5. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101226.
MS-PA
Digital speed control within the range of 0-1500rpm. Maximum stirring quantity of H2O at 3L. LED display shows stirring speed. Categories: Labooratory Mixers, Shakers & Stirrers.
MspA1 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 10-fold overdigestion with enzyme 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 500 U; 2500U. CMG↑CKG GKC↓GMC. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y, BSA. Storage: -20°C. Storage at -70°C is recommended for periods longer than 30 days. Form: Liquid. Source: Moraxella species A1. Pack: 20 mM Tris-HCl (pH 7.6); 300 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 10 mM MgCl2, 200 μg/ml BSA, 50% glycerol. Cat No: ET-1140RE.
MS-PB
Digital speed control within the range of 0-1500rpm. Maximum stirring quantity of H2O at 3L. Categories: Labooratory Mixers, Shakers & Stirrers.
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. C↑CGG GGC↓C. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer B. Storage: -20°C. Form: Liquid. Source: Moraxella species. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM KCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1139RE.
MspR9 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (dcm-) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 2-fold mspr9 i overdigestion >5% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. CC↑NGG GGN↓CC. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer O. Storage: -20°C. Form: Liquid. Source: Micrococcus species R9. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoetyanol; 100 μg/ml BSA; and 50% glycerol. Cat No: ET-1141RE.
MST-312
MST-312 is a telomerase inhibitor. MST-312 is a chemically modified derivative of green tea epigallocatechin gallate (EGCG). MST-312 can be used for the research of cancer, such as multiple myeloma (MM)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Telomerase Inhibitor IX. CAS No. 368449-04-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120145.
MST-312
MST-312 is an inhibitor of telomerase, an enzyme responsible for telomere maintenance in almost all human cancer cells. MST-312 showed cytotoxic action and promoted telomere erosion, senescence, and chromosome aberrations in a small proportion. Study has shown that MST312 inhibited replication of HSV, interfering the life cycle of virus. Alternative Names: Telomerase Inhibitor IX; N-[3-[(2,3-dihydroxybenzoyl)amino]phenyl]-2,3-dihydroxybenzamide. Grades: ≥98%. CAS No. 368449-04-1. Molecular formula: C20H16N2O6. Mole weight: 380.35.
MSTFA Reagent
MSTFA Reagent. Uses: For analytical and research use. CAS No. 24589-78-4. Mole weight: 199.25. EC Number: 246-331-6. Catalog: AP24589784-A.
MSTP
MSTP is a selective and highly reactive thiol blocking reagent compatible with a variety of experimental setups in biological research. Alternative Names: 4-(5-(Methylsulfonyl)-1H-tetrazol-1-yl)phenol. Grades: 99%. CAS No. 2125668-23-5. Molecular formula: C8H8N4O3S. Mole weight: 240.24.
MSU38225
MSU38225 is an Nrf-2 inhibitor that increases levels of reactive oxygen species (ROS). MSU38225 inhibits the growth of human lung cancer cells and enhances the sensitivity of human lung cancer cells to chemotherapy in vitro and in vivo. MSU38225 can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1629160-83-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153873.
MSX-122
MSX-122 is an orally active partial antagonist of CXCR4, inhibiting CXCR4/CXCL12 actions, with an IC50 of ?10 nM. MSX-122 has anti-inflammatory and anti-metastatic activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 897657-95-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13696.
MT1
MT1 is a bivalent chemical probe of BET bromodomains, with an IC50 of 0.789 nM for BRD4(1)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2060573-82-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111976.
MT-110
MT-110 (BPN-0027490) is a non-muscle myosin NMIIB-selective inhibitor with high brain penetration and favorable safety profile. MT-110 specifically disrupts NMIIB-dependent actin dynamics in dendritic spines, while it exerts no significant adverse effects on cardiac myosin II and cardiac functions (such as cardiac output and heart rate) at tested concentrations. A single administration of MT-110 produces long-lasting (sustained for several weeks) blockade of methamphetamine motivation associated with environmental cues. MT-110 exhibits extremely high specificity, with no interference with cocaine motivation, hippocampus-dependent memory, fear memory, or locomotor and anxiety-like behaviors. MT-110 serves as a valuable tool compound for investigating the mechanisms of methamphetamine use disorder[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BPN-0027490. CAS No. 2404652-82-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175188.
MT-125 free base
MT-125 free base is a specific and well-tolerated inhibitor of non-muscle myosin IIA (Ki,NMIIA = 2.7 μM) and IIB (EC50 = 1.7 μM). MT-125 free base can pass through the blood-brain barrier. MT-125 free base induces ferroptosis and DNA damage by increasing the levels of reactive oxygen species (ROS) within tumor cells. MT-125 free base can enhance the PDGFR signaling pathway. MT-125 free base can be used for research on glioblastoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2404652-80-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-174406A.
MT-228
MT-228 (BPN-0026709) is a selective and blood-brain barrier permeable non-muscle myosin II inhibitor. MT-228 markedly improves tolerability by selectively targeting NMIIB (KI = 1.5 μM) over CMII (KI = 17 μM), and the sequence of SmMll MD is 83.6% identical to that of NMllB. MT-228 shows long-lasting efficacy in animal models of stimulant use disorder[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BPN-0026709. CAS No. 2404652-24-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175199.
MT-4
MT-4 is a derivative of a tissue transglutaminase (TG2) inhibitor. MT-4 targets the complex of TG2 and fibronectin (FN) (TG2/FN) and inhibits the adhesion of tumor cells to the matrix. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum and increases the sensitivity of OC cells to paclitaxel. Uses: Scientific research. Category: Signaling pathways. CAS No. 2327925-35-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128595.
MT 63-78
MT 63-78 is a specific and potent direct AMPK activator with an EC50 of 25 μM. MT 63-78 also induces cell mitotic arrest and apoptosis. MT 63-78 blocks prostate cancer growth by inhibiting the lipogenesis and mTORC1 pathways. MT 63-78 has antitumor effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1179347-65-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-W058849.
MT-802
MT-802 is a BTK PROTAC degrader. MT-802 degrades wild-type BTK (DC50 = 14.6 nM) and BTK mutants including E41K, C481S (DC50 = 14.9 nM), C481R, C481Y, C481T, C481F, L528W, and inhibits their Y223 phosphorylation. BI-4732 can be used for the study of Ibrutinib (HY-10997)-resistant chronic lymphocytic leukemia (CLL). (Pink: BTK ligand (HY-150885), Blue: CRBN Ligand (HY-14658), Black: Linker (HY-141371), E3 ligase ligand-linker conjugate (HY-176340))[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2231744-29-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122562.
MT 81
MT 81 is a plant toxin that comes from Penicillum nigricans. It has anti-Gram-positive bacteria activity. Alternative Names: Mycotoxin 81; Mycotoxin MT 81; MT81; BRN 4596898; 1,5-Dihydroxy-3-methyl-8-[(2,6,7,7a-tetrahydro-4H-furo[3,2-c]pyran-4-yl)oxy]-9,10-anthracenedione. CAS No. 93513-59-8. Molecular formula: C22H18O7. Mole weight: 394.37.
MTBE
MTBE. CAS No. 1634-04-4. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
MT-DADMe-ImmA
MT-DADMe-ImmA is an inhibitor of human 5'-methylthioadenosine phosphorylase (MTAP) with a Ki of 90 pM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MTDIA; Methylthio-DADMe-Immucillin A. CAS No. 653592-04-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101496.
MTDH-SND1 blocker 1
MTDH-SND1 blocker 1 (compound C26-A6) is an inhibitor of the MTDH-SND1 protein. MTDH-SND1 blocker 1 inhibits cancer metastasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1341030-00-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155170.
MTDIA
MTDIA is a human 5'-methylthioadenosine phosphorylase (MTAP) inhibitor, which is solely responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. It is used as an anticancer candidate. Alternative Names: Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium. Grades: 98%. CAS No. 653592-04-2. Molecular formula: C13H19N5OS. Mole weight: 294.35.
MTDIA hydrochloride
MTDIA is a methylthioadenosine phosphorylase (MTAP) inhibitor. MTAP is responsible for 5'-methylthioadenosine (MTA) metabolism to permit S-adenosylmethionine salvage. Transition-state (TS) analogues of MTAP are in development as anticancer drug candidates and MTDIA is one of these TS analogues. Uses: Anticancer drug candidate. Alternative Names: (3R,4S)-1-((4-amino-5H-pyrrolo[3,2-d]pyrimidin-7-yl)methyl)-3-hydroxy-4-((methylthio)methyl)pyrrolidin-1-ium chloride; MTDIA; MTDIA HCl; Methylthio-DADMe-Immucillin A; MT-DADMe-ImmA; MT-DADMe-ImmA HCl. Grades: 98%. CAS No. 1399840-35-7. Molecular formula: C13H20ClN5OS. Mole weight: 329.85.
MTEP
Potent and selective antagonist for mGluR5. 5-fold higher anxiolytic activity than MPEP. Antidepressant. Neuroprotective. Produces anti-parkinsonian-like effects in rats. Group: Biochemicals. Alternative Names: 3-pyridine. Grades: Highly Purified. CAS No. 329205-68-7. Pack Sizes: 5mg, 25mg. Molecular Formula: C11H8N2S. US Biological Life Sciences.
Worldwide
MTEP hydrochloride
MTEP hydrochloride is a potent, non-competitive and highly selective mGluR5 antagonist, with an IC50 of 5 nM and a Ki of 16 nM. MTEP hydrochloride shows antidepressant and anxiolytic-like effects. MTEP hydrochloride can be used for Parkinson's disease research[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1186195-60-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13206.
MTEP Hydrochloride
MTEP Hydrochloride. Group: Biochemicals. Alternative Names: 3-[ (2-Methyl-4-thiazolyl) ethynyl]pyridine; 3-[(2-Methyl-1,3-thiazol-4-yl)ethynyl]pyridine Hydrochloride. Grades: Highly Purified. CAS No. 329205-68-7. Pack Sizes: 10mg. Molecular Formula: C11H9ClN2S, Molecular Weight: 236.72. US Biological Life Sciences.
A non-competitive, potent antagonist highly selective for mGlu5 receptors (IC50 = 5nM). Biologically active admitted orally or systematically. Widely used in assessing the functional roles of mGlu5 receptors in a variety of research areas, such as neuroprotection, depression, addiction, anxiety and stress related disorders, analgesia, locomotion, neural plasticity, and Parkinson's disease. Group: Biochemicals. Grades: Highly Purified. CAS No. 1186195-60-7. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
m-Terphenyl
White powder, 99%. Synonym: 1,3-Diphenylbenzene. CAS No. 92-06-8. Pack Sizes: Typically in stock: 50g, 250g. Mole weight: 230.31. MP/BP: M.P. 87. Order No: FR-3040.
Frinton Laboratories
m-Terphenyl
m-Terphenyl (CAS# 92-06-8) is a useful research chemical. Alternative Names: 1,1':3',1''-Terphenyl; m-Diphenylbenzene; meta-terphenyl. Grades: 99 %. CAS No. 92-06-8. Molecular formula: C18H14. Mole weight: 230.30.
M-Terphenyl
M-terphenyl is a yellow solid. mp: 86-87° C, bp: 365°C. Density: 1.195 g/cm³. Insoluble in water. Usually shipped as a solid mixture with its isomers o-terphenyl and p-terphenyl that is used as a heat-transfer fluid.;Colorless or light-yellow solid.;Yellow solid (needles). Alternative Names: m-Diphenylbenzene. CAS No. 92-06-8. Molecular formula: C18H14. Mole weight: 230.3. Purity: 99%. IUPAC Name: 1,3-Diphenylbenzene. SMILES: C1=CC=C(C=C1)C2=CC(=CC=C2)C3=CC=CC=C3. InChI: InChI=1S/C18H14/c1-3-8-15(9-4-1)17-12-7-13-18(14-17)16-10-5-2-6-11-16/h1-14H.
A peptide fragment of mTERT. Mouse telomerase reverse transcriptase (mTERT) is a gene that is expressed by cells that need to continually divide without the characteristic shortening of telomeres that accompanies DNA replication. Alternative Names: hTERT R572Y peptide; Mouse telomerase reverse transcriptase (572-580).
Mth-dl-glutamic acid
Mth-dl-glutamic acid. CAS No. 1801-64-5. Purity: 96%. Product ID: ACM1801645. Alfa Chemistry - ISO 9001:32057 Certified.