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| Product | Description | |
|---|---|---|
| Pivalic acid-d9 | Pivalic acid-d9 is the deuterium labeled Pivalic acid[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Trimethylmethanecarboxylic acid-d9; Versatic 5 acid-d9; tert-Pentanoic acid-d9. CAS No. 42983-07-3. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-Y1150S2. |  |
| Pivalic acid hydrazide | Pivalic acid hydrazide. Group: Biochemicals. Grades: Highly Purified. CAS No. 42826-42-6. Pack Sizes: 2g, 5g, 10g, 25g. US Biological Life Sciences. |  Worldwide |
| Pivalonitrile | Pivalonitrile. Group: Biochemicals. Alternative Names: Trimethylacetonitrile. Grades: Highly Purified. CAS No. 630-18-2. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C5H9N. US Biological Life Sciences. | Worldwide |
| Pivaloylacetonitrile | Pivaloylacetonitrile. Group: Biochemicals. Grades: Highly Purified. CAS No. 59997-51-2. Pack Sizes: 1kg, 2kg, 5kg, 10kg, 25kg. US Biological Life Sciences. | Worldwide |
| Pivaloyl Hydrazide | Pivaloyl Hydrazide (CAS# 42826-42-6) is a useful research chemical. Alternative Names: 2,2-dimethylpropanehydrazide; 2,2-dimethylpropanehydrazide. CAS No. 42826-42-6. Molecular formula: C5H12N2O. Mole weight: 116.16. |  |
| Pivampicillin | Pivampicillin, an ester that hydrolyzes to ampicillin in vivo, is a semi-synthetic antibiotic. Alternative Names: 4-thia-1-azabicyclo(3.2.0)heptane-2-carboxylicacid,6-(2-amino-2-phenylacetami; ampicillinpivaloyloxymethylester; hydroxymethylester,pivalate(ester),d-(-)-do)-3-dimethyl-7-oxo-; mk191; pivaloylampicillin; pivaloyloxymethylampicillinate; PIVAMPICILLIN; PIVAPICILL. Grades: > 95%. CAS No. 33817-20-8. Molecular formula: C22H29N3O6S. Mole weight: 463.56. | |
| Pivampicillin Hydrochloride | Pivampicillin, an ester that hydrolyzes to ampicillin in vivo, is a semi-synthetic antibiotic. Uses: Anti-bacterial agents. Alternative Names: (2S,5R,6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (2,2-Dimethyl-1-oxopropoxy)methyl Ester Hydrochloride; Alphacilina; Ampicillin Pivaloxyoxymethyl Ester Hydrochloride; Berocillin; Centurina; Diancina; Inacilin; Maxifen; Pivaloyloxymethyl D-(-)-α-Aminophenylacetamidopenicillanate Hydrochloride; Pivatil; Pondocil; Pondocillin; Pondocillina; Sanguicillin; Alphacilina; Diancina; pivampicillin,hydrochloride; ((R)-amino-phenyl-methyl)-penicillin 2,2-dimethyl-propionyloxymethyl ester,hydrochloride; Pivampicillin Hydrochloride; Alphacillin; Sanguicillin; Devonium; Diancina; Serra Pamies Brand of Pivampicillin Hydrochloride; Pivampicillin Monohydrochloride; Leo Brand of Pivampicillin; Monohydrochloride, Pivampicillin. Grades: 97%. CAS No. 26309-95-5. Molecular formula: C22H30ClN3O6S. Mole weight: 500.01. | |
| Pivampicillin Hydrochloride | Semi-synthetic antibiotic related to Penicillin. Antibacterial. Group: Biochemicals. Alternative Names: (2S, 5R, 6R)-6-[[(2R)-2-Amino-2-phenylacetyl]amino]-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo[3. 2. 0]heptane-2-carboxylic Acid (2,2-Dimethyl-1-oxopropoxy)methyl Ester Hydrochloride Alphacilina; Alphacillin; Ampicillin Pivaloxyoxymethyl Ester Hydrochloride; Berocillin; Centurina; Diancina; Inacilin; Maxifen; Pivaloyloxymethyl D- (-) - α -Aminophenyl acetamidopenicillanate Hydrochloride; Pivatil; Pondocil; Pondocillin; Pondocillina; Sanguicillin. Grades: Purified. CAS No. 26309-95-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Pivarose | Pivarose (Phenyl Ethyl Pivalate). CAS No. 67662-96-8. Kosher: Y. VIGON Item # 500875. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| Pivekimab | Pivekimab is a human IgG1 monoclonal antibody that targets interleukin-3 (IL-3) and CD123. Pivekimab is used to synthesize pivekimab sunirine, a CD123-directed antibody-active molecule conjugate (ADC). Pivekimab is used in the study of blastic plasmacytoid dendritic cell neoplasm (BPDCN)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2234335-84-1. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99234. | |
| Pividium bromide impurity 10 | Pividium bromide impurity 10. Uses: For analytical and research use. CAS No. 1970218-70-2. Molecular formula: C26H41Br2NO4. Mole weight: 591.43. Catalog: APB1970218702. |  |
| Pividium bromide impurity 11 | Pividium bromide impurity 11. Uses: For analytical and research use. Molecular formula: C15H23Br2NO4. Mole weight: 441.16. Catalog: APB11355. | |
| Pividium bromide impurity 12 | Pividium bromide impurity 12. Uses: For analytical and research use. Molecular formula: C15H22BrClNO3+. Mole weight: 379.7. Catalog: APB11357. | |
| Pividium bromide impurity 13 | Pividium bromide impurity 13. Uses: For analytical and research use. Molecular formula: C27H41Br2NO3. Mole weight: 587.44. Catalog: APB11356. | |
| Pividium bromide impurity 14 | Pividium bromide impurity 14. Uses: For analytical and research use. CAS No. 53207-00-4. Molecular formula: C9H10Br2O2. Mole weight: 309.99. Catalog: APB53207004. | |
| Pividium bromide impurity 15 | Pividium bromide impurity 15. Uses: For analytical and research use. CAS No. 1235355-01-7. Molecular formula: C26H39Br2NO4. Mole weight: 589.41. Catalog: APB1235355017. | |
| Pividium bromide impurity 16 | Pividium bromide impurity 16. Uses: For analytical and research use. Molecular formula: C17H31NO2. Mole weight: 281.44. Catalog: APB11358. | |
| Pividium bromide impurity 17 | Pividium bromide impurity 17. Uses: For analytical and research use. Molecular formula: C11H20O. Mole weight: 168.28. Catalog: APB11359. | |
| Pividium bromide impurity 2 | Pividium bromide impurity 2. Uses: For analytical and research use. CAS No. 473-00-7. Molecular formula: C11H16. Mole weight: 148.25. Catalog: APB473007. | |
| Pividium bromide impurity 3 | Pividium bromide impurity 3. Uses: For analytical and research use. Molecular formula: C11H20O2. Mole weight: 184.28. Catalog: APB11352. | |
| Pividium bromide impurity 4 | Pividium bromide impurity 4. Uses: For analytical and research use. Molecular formula: C11H18O. Mole weight: 166.26. Catalog: APB11351. | |
| Pividium bromide impurity 5 | Pividium bromide impurity 5. Uses: For analytical and research use. Molecular formula: C12H20O2. Mole weight: 196.29. Catalog: APB11353. | |
| Pividium bromide impurity 6 | Pividium bromide impurity 6. Uses: For analytical and research use. CAS No. 64773-71-3. Molecular formula: C11H18O. Mole weight: 166.26. Catalog: APB64773713. | |
| Pividium bromide impurity 7 | Pividium bromide impurity 7. Uses: For analytical and research use. CAS No. 7712-52-9. Molecular formula: C17H29NO2. Mole weight: 279.42. Catalog: APB7712529. | |
| Pividium bromide impurity 8 | Pividium bromide impurity 8. Uses: For analytical and research use. Molecular formula: C26H41BrNO4+. Mole weight: 511.52. Catalog: APB11354. | |
| Pividium bromide impurity 9 | Pividium bromide impurity 9. Uses: For analytical and research use. CAS No. 135964-95-3. Molecular formula: C26H41Br2NO4. Mole weight: 591.43. Catalog: APB135964953. | |
| Pivmecillinam Hydrochloride | Pivmecillinam Hydrochloride is the hydrochloride salt of Pivmecillinam, which is an orally active prodrug of the broad-spectrum penicillin antibiotic Mecillinam. Pivmecillinam is only thought to be active against Gram-negative bacteria and is mainly used to treat lower urinary tract infections. Uses: Anti-bacterial agents. Alternative Names: (2S,5R,6R)-6-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (2,2-Dimethyl-1-oxopropoxy)methyl Ester Hydrochloride; pivmecillinam hydrochloride; 2-Pyrrolidinecarboxamide,1-(2,2-dimethyl-1-oxopropyl)-N-methyl; Piv-DL-Pro-NHMe; Amdinocillin Pivoxil; FL 1039; FL-1039; FL1039; Hydrochloride, Pivmecillinam. Grades: ≥95%. CAS No. 32887-03-9. Molecular formula: C21H34ClN3O5S. Mole weight: 476.03. | |
| Pivmecillinam Hydrochloride | Pivmecillinam Hydrochloride. Group: Biochemicals. Alternative Names: (2S, 5R, 6R)-6-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo[3. 2. 0]heptane-2-carboxylic Acid (2,2-Dimethyl-1-oxopropoxy)methyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 32887-03-9. Pack Sizes: 50mg. Molecular Formula: C21H34ClN3O5S, Molecular Weight: 476.03. US Biological Life Sciences. | Worldwide |
| Pixantrone | Pixantrone (BBR 2778) dimaleate is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BBR 2778. CAS No. 144675-97-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13727A. | |
| Pixantrone Impurity 1 | Pixantrone Impurity 1. Uses: For analytical and research use. CAS No. 144510-98-5. Molecular formula: C17H17N3O4. Mole weight: 327.34. Catalog: APB144510985. | |
| Pixantrone Impurity 2 | Pixantrone Impurity 2. Uses: For analytical and research use. CAS No. 1430561-04-8. Molecular formula: C15H14N4O2. Mole weight: 282.3. Catalog: APB1430561048. | |
| Pizotifen | Pizotifen (Pizotyline) is a potent 5-HT2 receptor antagonist, with a high affinity for 5-HT1C binding site. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pizotyline; BC-105. CAS No. 15574-96-6. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg. Product ID: HY-B0115. | |
| Pizotifen malate | Pizotifen is a benzocycloheptene-based drug used for the treatment of recurrent migraine headaches. It acts as an antagonist of 5-HT2A and 5HT2C receptors. Alternative Names: BC-105; BC 105; BC105. Grades: >98%. CAS No. 5189-11-7. Molecular formula: C19H21NS·C4H6O5. Mole weight: 429.53. | |
| Pizotifen malate | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H21NS.C4H6O5. CAS No. 5189-11-7. Prepack ID 12889487-1g. Molecular Weight 429.53. See USA prepack pricing. |  |
| Pizotyline | Serotonin antagonist structurally related to Cyproheptadine. Antimigraine; appetite stimulant. Group: Biochemicals. Alternative Names: 4-(9, 10-Dihydro-4H-benzo[4, 5]cyclohepta[1, 2-b]thien-4-ylidene)-1-methylpiperidine. Grades: Highly Purified. CAS No. 15574-96-6. Pack Sizes: 1g. US Biological Life Sciences. | Worldwide |
| PJ34 | PJ34 is a potent specific inhibitor of PARPl/2 with IC50 of 110 nM and 86 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 344458-19-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-13688A. | |
| PJ34 | PJ34 is a novel and potential PARP inhibitor with potential anticancer activity. PJ34 has a high affinity for PARP-1 (IC(50) = 20 nM). Alternative Names: PJ34; PJ-34; PJ 34. CAS No. 344458-15-7. Molecular formula: C17H18ClN3O2. Mole weight: 331.8. | |
| PJ 34 Hydrochloride | A poly adenosine diphosphate-ribose polymerase inhibitor, attenuates chromate-induced nephrotoxicity. Group: Biochemicals. Alternative Names: N- (5, 6-Dihydro-6-oxo-2-phenanthridinyl) -2- (dimethylamino) acetamide. Grades: Highly Purified. CAS No. 344458-15-7. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| PJ-34 Hydrochloride | A potent, water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC50 = 20nM). Inhibits peroxynitrite-induced cell necrosis and displays significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Suppresses cell growth in liver cancer cells. Group: Biochemicals. Alternative Names: N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. | Worldwide |
| PJ-34 (N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide. HCl) | Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor. Inhibits peroxynitrite-induced cell necrosis. Shows significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Shows protective effects in models of stroke. Suppresses cell growth in liver cancer cells. Group: Biochemicals. Alternative Names: N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide. HCl. Grades: Highly Purified. CAS No. 344458-15-7. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences. | Worldwide |
| pJAK2(1001-1013) | pJAK2(1001-1013) is a cell-penetrating peptide that corresponds to the activation loop of JAK2 tyrosine kinase and functions as a SOCS1/3antagonist. pJAK2 (1001-1013) blocks SOCS1-mediated negative regulation of immune function, and enhances the biological activity of cytokines such as IFNγ and IL6. pJAK2(1001-1013) inhibits the replication of a broad range of viruses and exerts dose-dependent protective efficacy against lethal viral infections. pJAK2(1001-1013) can be used for the study of immune regulation and infection[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1259928-08-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P10373. | |
| PK11007 | PK11007 is a mild thiol alkylator with anticancer activity. PK11007 stabilizes p53 via selective alkylation of two surface-exposed cysteines without compromising its DNA binding activity. PK11007 induces mutant p53 cancer cell death by increasing reactive oxygen species (ROS) levels[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 874146-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128784. | |
| PK11195 | An isoquinoline carboxamide that acts as a potent ligand for peripheral bezodiazepine receptor (Kd = 20nM). Exhibits anti-inflammatory properties. Binds to monocytes and following lesioning its binding up-regulated in brain macrophages and activated microglia. Shown to enhance the susceptibility of cells to apoptosis induction by DNA damaging agents and can reverse the suppression of apoptosis by Bcl-2. Serves as a ligand of the outer membrane translocator protein and reduces mitochondrial transmembrane potential within 30 minutes of exposure (100uM).CAS Number:85532-75-8. Group: Biochemicals. Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O. US Biological Life Sciences. | Worldwide |
| PK 11195 | Cell-permeable. A Selective peripheral benzodiazepine antagonist. Enhances apoptosis and induces mitochondria cytochrome c release. Inhibits insulin secretion induced by glucose. Also displays anticancer activity. Group: Biochemicals. Alternative Names: 1- (2-Chloro phenyl ) -N- methyl -N- (1- methyl propyl ) -3-isoquinolinecarboxamid e. Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| PK 11195 | PK 11195 (RP 52028) is a ligand of translocator protein (TSPO), which targets Leishmania chemotherapy, with IC50s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis, L. major and L. braziliensis, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RP 52028. CAS No. 85532-75-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19567. | |
| PK150 | PK150, an analogue of Sorafenib, shows oral bioavailability and antibacterial activity against several pathogenic strains at submicromolar concentrations. PK150 inhibits Gram-positive Methicillin-sensitive S. aureus (MSSA), Methicillin-resistant S. aureus (MRSA), Vancomycin intermediate S. aureus (VISA) with MICs of 0.3, 0.3-1, 0.3 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2165324-62-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-133119. | |
| Pk 44 phosphate | Pk 44 phosphate. CAS No. 1017682-65-3. Purity: >98 %. Product ID: ACM1017682653. Molecular formula: C17H16F5N7O.H3PO4. Mole weight: 527.34. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| PK 44 phosphate | PK 44 phosphate. Group: Biochemicals. Grades: Purified. CAS No. 1017682-66-4. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| PK68 | PK68 is a potent orally active and specifical type II inhibitor of receptor-interacting kinase 1 (RIPK1) with an IC50 of ~90?nM, displays inhibition of RIPK1-dependent necroptosis. PK68 powerfully ameliorates TNF-induced systemic inflammatory response syndrome, and can be used for the research of inflammatory disorders and cancer metastasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2173556-69-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128348. | |
| PK9327 | PK9327 is a small-molecule stabilizer targeting cavity-creating p53 cancer mutations. Uses: Scientific research. Category: Signaling pathways. CAS No. 2413987-20-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145937. | |
| PKA-IN-1 | PKA-IN-1 is a potent and selective cyclic AMP-dependent protein kinase (PKA) catalytic subunit (cAK) inhibitor with an IC50 of 0.03 μM. PKA-IN-1 inhibits cAK in a fashion that is competitive with respect to ATP as substrate[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 179985-52-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg. Product ID: HY-115732. | |
| PKA inhibitor fragment (6-22) amide | PKA inhibitor fragment (6-22) amide is a synthetic peptide inhibitor of cAMP-dependent protein kinase (PKA) (Ki = 2.5 nM) derived from the heat-stable PKA inhibitor protein PKI. It is the shortest synthetic PKI peptide that retains high potency for PKA inhibition. Alternative Names: PKI (6-22) amide; H-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2; L-threonyl-L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-seryl-glycyl-L-arginyl-L-threonyl-glycyl-L-arginyl-L-arginyl-L-asparagyl-L-alanyl-L-isoleucinamide; Tyadfiasgrtgrrnai-nh2; Protein Kinase A Inhibitor Fragment 6-22 amide. Grades: ≥95%. CAS No. 121932-06-7. Molecular formula: C80H130N28O24. Mole weight: 1868.08. | |
| PKA Inhibitor Fragment (6-22) amide | PKA Inhibitor Fragment (6-22) amide is a highly potent and specific competitive inhibitor of PKA, with Ki values of 1.7 nM and 1.6 nM against human and bovine PKA catalytic subunits, respectively. The IC50 of PKA Inhibitor Fragment (6-22) amide targeting bovine PKA is 8.6 nM. PKA Inhibitor Fragment (6-22) amide effectively abolishes PKA activity in mouse brain and spinal cord, and exerts in vivo efficacy via intracerebroventricular administration. PKA Inhibitor Fragment (6-22) amide significantly reverses low-dose morphine analgesic tolerance in mice and blocks photoaffinity labeling of cAMP-dependent protein kinase. PKA Inhibitor Fragment (6-22) amide can be applied to research in fields related to the mechanism of morphine analgesic tolerance and skin wound healing[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PKI-(6-22)-amide. CAS No. 121932-06-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1290. | |
| PKA inhibitor fragment (6-22) amide acetate | PKA Inhibitor Fragment (6-22) amide acetate is a synthetic peptide inhibitor of cAMP-dependent protein kinase (PKA) (Ki = 2.5 nM), derived from the heat-stable PKA inhibitor protein PKI. It is the shortest synthetic PKI peptide that retains high potency for PKA inhibition. Alternative Names: H-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2.CH3CO2H; L-threonyl-L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-seryl-glycyl-L-arginyl-L-threonyl-glycyl-L-arginyl-L-arginyl-L-asparagyl-L-alanyl-L-isoleucinamide acetic acid. Grades: ≥95%. Molecular formula: C82H134N28O26. Mole weight: 1928.11. | |
| PKA Regulatory Subunit II Substrate | PKA Regulatory Subunit II Substrate (RII phosphopeptide) is a tool peptide derived from the regulatory subunit Type II (RII) of cyclic AMP-dependent protein kinase (PKA). PKA Regulatory Subunit II Substrate is commonly used to mimic the phosphorylation of protein kinases and as a specific substrate for protein phosphatases to assess the activities of these enzymes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RII phosphopeptide. CAS No. 103659-06-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P10602. | |
| PKC (19-36) | PKC (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (IC50 = 0.18 μM). Alternative Names: Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly. Grades: >97%. CAS No. 113731-96-7. Molecular formula: C93H159N35O24. Mole weight: 2151.48. | |
| PKC Activator VII, CGK062 (Protein Kinase C Activator VII) | A cell permeable coumarin-containing compound that is shown to activate PKCalpha activity and induce cellular PKCalpha membrane translocation (Effective conc. 12.5 to 50uM) as well as PKCalpha-mediated signaling events. Effectively affects the viability of CRT-dependent cancer cells (IC50 = 1.62 to 18.6uM; 48h) in vitro and suppresses PC3-derived tumor expansion in mice (50 & 100mg/kg/day; i.p) in vivo, while exhibiting little cytotoxicity toward WI38 normal fibroblasts. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??O?, Primary Target IC50: 12.2uM. US Biological Life Sciences. | Worldwide |
| PKCβII Peptide Inhibitor I trifluoroacetate salt | PKCβII Peptide Inhibitor I trifluoroacetate salt. Uses: For analytical and research use. CAS No. 862502-26-9 (free base). Mole weight: 1299.47 (free base basis). Catalog: ALP862502269. | |
| PKC β pseudosubstrate | PKC β pseudosubstrate, a selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM), consists of amino acids 19-31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain vector peptide. Alternative Names: PKC beta pseudosubstrate; Protein kinase C beta pseudosubstrate; H-Cys(1)-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH.H-Cys(1)-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-OH; L-cysteinyl-L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine (1->1')-disulfide compound with L-cysteinyl-L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparagyl-L-valine. Grades: >98%. CAS No. 172308-76-8. Molecular formula: C177H294N62O38S3. Mole weight: 3994.84. | |
| PKC-iota inhibitor 1 | PKC-iota inhibitor 1 is an inhibitor of protein kinase C-iota with an IC50 value of 0.34 μM. Alternative Names: 2-Amino-5-(3-(piperazin-1-yl)phenyl)-N-(pyridin-4-yl)nicotinamide. Grades: 98%. CAS No. 2328094-11-5. Molecular formula: C21H22N6O. Mole weight: 374.44. | |
| PKC-Theta Inhibitor | PKC-theta inhibitor is a selective PKC-theta inhibitor with IC50 of 12 nM. Alternative Names: CHEMBL248183; N4-((4-(Aminomethyl)Cyclohexyl)Methyl)-5-Nitro-N2-(2-(Trifluoromethoxy)Benzyl)Pyrimidine-2,4-Diamine; VC-8650; SCHEMBL3953579. Grades: 98%. CAS No. 736048-65-0. Molecular formula: C20H25F3N6O3. Mole weight: 454.4. | |
| PKC-theta inhibitor 1 | PKC-theta inhibitor 1 is an orally active and selective ATP-competitive inhibitor of Protein Kinase Cθ (PKCθ), with a Ki value of 6 nM. PKC-theta inhibitor 1 inhibits T-cell-mediated inflammatory responses by suppressing the release of proinflammatory cytokines (IL-2 IC50 = 0.21 μM in anti-CD3/CD28-stimulated PBMCs; IL-17 IC50 = 1 μM in CD3/CD28-stimulated Th17 cells) PKC-theta inhibitor 1 significantly reduces symptoms in mice with ongoing experimental autoimmune encephalomyelitis (EAE). PKC-theta inhibitor 1 can be used for the study of T-cell-mediated inflammatory diseases such as multiple sclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1160501-81-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-126328. | |
| PKC-theta inhibitor 2 | PKC-theta inhibitor 2 is a potent and selective PKC-θ inhibitor with an IC50 value of 18 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 736048-65-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112681. | |
| PKCζ-IN-1 | PKCζ-IN-1 is a compound that inhibits PKCζ and CDK2, showing an IC50 value of 5.18 nM for PKCζ and 1.04 μM for CDK2, with significant selectivity of 200-fold. PKCζ-IN-1 can reduce the activity of CDK2 while inhibiting PKCζ. Uses: Scientific research. Category: Signaling pathways. CAS No. 1132609-87-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-120497. | |
| PKC ζ pseudosubstrate acetate | PKC ζ pseudosubstrate acetate, a synthetic peptide, is an inhibitor of protein kinase C (PKC) ζ that is attached to cell permeabilization Antennapedia domain vector peptide. It consists of amino acids 113-129 PKC ζ pseudosubstrate domains connected by a disulfide bridge to the cell permeabilization Antennapedia domain vector peptide. Alternative Names: Protein kinase C zeta pseudosubstrate acetate; L-cysteinyl-L-seryl-L-isoleucyl-L-tyrosyl-L-arginyl-L-arginyl-glycyl-L-alanyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-lysyl-L-leucyl-L-tyrosyl-L-arginyl-L-alanyl-L-asparagine (1->1')-disulfide compound with L-cysteinyl-L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine; H-Cys-Ser-Ile-Tyr-Arg-Arg-Gly-Ala-Arg-Arg-Trp-Arg-Lys-Leu-Tyr-Arg-Ala-Asn-OH.H-Cys-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH (Disulfide bridge: Cys1-Cys1'). Grades: ≥95%. Molecular formula: C210H340N74O46S3. Mole weight: 4733.68. | |
| PKG Drug G1 | PKG drug G1 is an activator of protein kinase GIα (PKGIα). It induces vasodilation and blood pressure reduction through the C42 PKG Iα independent mechanism. Alternative Names: Thiourea Deriv. 8; BDBM6641; CHEMBL141962; ZPA70378; HY-112197. Grades: 98%. CAS No. 374703-78-3. Molecular formula: C13H11N3OS. Mole weight: 257.31. | |
| PKG inhibitor peptide TFA | PKG inhibitor peptide TFA is an ATP-competitive inhibitor of cGMP-dependent protein kinase (PKG) with a Ki of 86 μM. It is an analog of a substrate peptide corresponding to a phosphorylation site of histone H2B, and inhibits phosphorylation of intact histones by PKA. Alternative Names: H-Arg-Lys-Arg-Ala-Arg-Lys-Glu-OH.TFA; L-arginyl-L-lysyl-L-arginyl-L-alanyl-L-arginyl-L-lysyl-L-glutamic acid trifluoroacetic acid; cGMP Dependent Kinase Inhibitor Peptide TFA. Grades: ≥95%. Molecular formula: C40H75F3N18O12. Mole weight: 1057.13. | |
| PKG Substrate | PKG Substrate is a selective substrate for cGMP-dependent protein kinase (PKG). Alternative Names: Arg-Lys-Arg-Ser-Arg-Ala-Glu; L-arginyl-L-lysyl-L-arginyl-L-seryl-L-arginyl-L-alanyl-L-glutamic acid; N5-(Diaminomethylidene)-L-ornithyl-L-lysyl-N5-(diaminomethylidene)-L-ornithyl-L-seryl-N5-(diaminomethylidene)-L-ornithyl-L-alanyl-L-glutamic acid; (S)-2-((6S,9S,12S,15S,18S,21S)-1,6-diamino-9-(4-aminobutyl)-12,18-bis(3-guanidinopropyl)-15-(hydroxymethyl)-1-imino-21-methyl-7,10,13,16,19-pentaoxo-2,8,11,14,17,20-hexaazadocosanamido)pentanedioic acid. Grades: ≥95%. CAS No. 81187-14-6. Molecular formula: C35H67N17O11. Mole weight: 902.01. | |
| PKG Substrate acetate | PKG Substrate acetate is a selective substrate for cGMP-dependent protein kinase (PKG). Alternative Names: H-Arg-Lys-Arg-Ser-Arg-Ala-Glu-OH.CH3CO2H; L-arginyl-L-lysyl-L-arginyl-L-seryl-L-arginyl-L-alanyl-L-glutamic acid acetic acid. Grades: ≥95%. Molecular formula: C37H71N17O13. Mole weight: 962.08. | |
| PKH 26 | PKH 26 is a red fluorescent dye, PKH 26 can stably bind to the lipid region of cell membrane and emit red fluorescence (Ex/Em=551/567 nm), which is mainly used for in vitro cell labeling, in vitro cell proliferation studies and in vivo and in vitro cell tracing studies[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 154214-55-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-D1451. | |
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