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Pividium bromide impurity 13. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C27H41Br2NO3. Mole Weight: 587.44. Catalog: APB11356.
Pividium bromide impurity 14
Pividium bromide impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 53207-00-4. Molecular Formula: C9H10Br2O2. Mole Weight: 309.99. Catalog: APB53207004.
Pividium bromide impurity 15
Pividium bromide impurity 15. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1235355-01-7. Molecular Formula: C26H39Br2NO4. Mole Weight: 589.41. Catalog: APB1235355017.
Pividium bromide impurity 16
Pividium bromide impurity 16. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H31NO2. Mole Weight: 281.44. Catalog: APB11358.
Pividium bromide impurity 17
Pividium bromide impurity 17. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C11H20O. Mole Weight: 168.28. Catalog: APB11359.
Pividium bromide impurity 2
Pividium bromide impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 473-00-7. Molecular Formula: C11H16. Mole Weight: 148.25. Catalog: APB473007.
Pividium bromide impurity 3
Pividium bromide impurity 3. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C11H20O2. Mole Weight: 184.28. Catalog: APB11352.
Pividium bromide impurity 4
Pividium bromide impurity 4. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C11H18O. Mole Weight: 166.26. Catalog: APB11351.
Pividium bromide impurity 5
Pividium bromide impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C12H20O2. Mole Weight: 196.29. Catalog: APB11353.
Pividium bromide impurity 6
Pividium bromide impurity 6. Uses: For analytical and research use. Group: Impurity standards. CAS No. 64773-71-3. Molecular Formula: C11H18O. Mole Weight: 166.26. Catalog: APB64773713.
Pividium bromide impurity 7
Pividium bromide impurity 7. Uses: For analytical and research use. Group: Impurity standards. CAS No. 7712-52-9. Molecular Formula: C17H29NO2. Mole Weight: 279.42. Catalog: APB7712529.
Pividium bromide impurity 8
Pividium bromide impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H41BrNO4+. Mole Weight: 511.52. Catalog: APB11354.
Pividium bromide impurity 9
Pividium bromide impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 135964-95-3. Molecular Formula: C26H41Br2NO4. Mole Weight: 591.43. Catalog: APB135964953.
Pivmecillinam
Pivmecillinam. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PIVMECILLINAM;PIVAMDINOCILLIN;AMDINOCILLIN PIVOXIL;PIVMECILLINAM IMPURITY CMETHYLENE 2,2-DIMETHYLPROPANOATE (2RS,4S)-2-[[[(HEXAHYDO-1H-AZEPIN-1-YL)METHYLENE]AMINO]METHYL]-5,5-DIMETHYLTHIAZOLIDIN-4-CARBOXYLATE EPP(CRM STANDARD);(2S,5β)-6α-[[(Hexahydro-1H-. Product Category: Heterocyclic Organic Compound. Appearance: crystals. CAS No. 32886-97-8. Molecular formula: C21H33N3O5S. Mole weight: 439.574. Product ID: ACM32886978. Alfa Chemistry ISO 9001:2015 Certified.
Pivmecillinam hydrochloride
Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FL-1039 hydrochloride. CAS No. 32887-03-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B0810A.
Pivmecillinam Hydrochloride
Pivmecillinam Hydrochloride. Group: Biochemicals. Alternative Names: (2S, 5R, 6R)-6-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]-3, 3-dimethyl-7-oxo-4-thia-1-azabicyclo[3. 2. 0]heptane-2-carboxylic Acid (2,2-Dimethyl-1-oxopropoxy)methyl Ester Hydrochloride. Grades: Highly Purified. CAS No. 32887-03-9. Pack Sizes: 50mg. Molecular Formula: C21H34ClN3O5S, Molecular Weight: 476.03. US Biological Life Sciences.
Worldwide
Pivmecillinam Hydrochloride
Pivmecillinam Hydrochloride is the hydrochloride salt of Pivmecillinam, which is an orally active prodrug of the broad-spectrum penicillin antibiotic Mecillinam. Pivmecillinam is only thought to be active against Gram-negative bacteria and is mainly used to treat lower urinary tract infections. Uses: Anti-bacterial agents. Synonyms: (2S,5R,6R)-6-[[(Hexahydro-1H-azepin-1-yl)methylene]amino]-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic Acid (2,2-Dimethyl-1-oxopropoxy)methyl Ester Hydrochloride; pivmecillinam hydrochloride; 2-Pyrrolidinecarboxamide,1-(2,2-dimethyl-1-oxopropyl)-N-methyl; Piv-DL-Pro-NHMe; Amdinocillin Pivoxil; FL 1039; FL-1039; FL1039; Hydrochloride, Pivmecillinam. Grades: ≥95%. CAS No. 32887-03-9. Molecular formula: C21H34ClN3O5S. Mole weight: 476.03.
Pivmecillinam (hydrochloride) (Standard)
Pivmecillinam (hydrochloride) (Standard) is the analytical standard of Pivmecillinam (hydrochloride). This product is intended for research and analytical applications. Pivmecillinam hydrochloride (FL-1039 hydrochloride) is an orally active proagent of mecillinam, an extended-spectrum penicillin antibiotic. Uses: Scientific research. Group: Signaling pathways. CAS No. 32887-03-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0810AR.
Pixantrone
Pixantrone (BBR 2778) dimaleate is a topoisomerase II inhibitor and DNA intercalator, with anti-tumor activity. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BBR 2778. CAS No. 144675-97-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13727A.
Pixantrone
6,9-Bis[(2-aminoethyl)amino]benz[g]isoquinoline-5,10-dione. antifungal and antiseptic. CAS No. 144510-96-3. Product ID: 8-04352. Molecular formula: C17H19N5O2. Mole weight: 325.37.
Pixantrone
Pixantrone is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non-Hodgkin lymphoma (aNHL). Uses: Topoisomerase ii inhibitors. Synonyms: Pixuvri; BBR-2778; BBR2778; BBR 2778. Grades: >98%. CAS No. 144510-96-3. Molecular formula: C17H19N5O2. Mole weight: 325.37.
Pixantrone Dimaleate
Pixantrone is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Pixantrone intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Pixantrone is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non-Hodgkin lymphoma (aNHL). Uses: Topoisomerase ii inhibitors. Synonyms: BBR 2778; BBR2778; BBR-2778; 6,9-Aea-biqdo; D05522; 5,8-Bis((2-aminoethyl)amino)-2-aza-anthracene-9,10-dione. Grades: >98%. CAS No. 144675-97-8. Molecular formula: C17H19N5O2.2C4H4O4??. Mole weight: 557.52.
Pixantrone Impurity 1
Pixantrone Impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 144510-98-5. Molecular Formula: C17H17N3O4. Mole Weight: 327.34. Catalog: APB144510985.
Pixantrone Impurity 1
An impurity of Pixantrone which is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Grades: > 95%. Molecular formula: C17H17N5O2. Mole weight: 323.36.
Pixantrone Impurity 2
An impurity of Pixantrone which intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Grades: > 95%. Molecular formula: C17H17N5O2. Mole weight: 323.36.
Pixantrone Impurity 2
Pixantrone Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1430561-04-8. Molecular Formula: C15H14N4O2. Mole Weight: 282.3. Catalog: APB1430561048.
Pixantrone Impurity 3
An impurity of Pixantrone which is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non-Hodgkin lymphoma (aNHL). Grades: > 95%. Molecular formula: C15H14N4O2. Mole weight: 282.3.
Pixantrone Impurity 4
An impurity of Pixantrone which is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity used to treat aggressive non-Hodgkin lymphoma (aNHL). Grades: > 95%. Molecular formula: C15H14N4O2. Mole weight: 282.3.
Pixantrone Impurity 5
An impurity of Pixantrone which is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity. Grades: > 95%. Molecular formula: C15H12FN3O2. Mole weight: 285.28.
Pixantrone Impurity 6
An impurity of Pixantrone which intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Grades: > 95%. Molecular formula: C15H12FN3O2. Mole weight: 285.28.
Pixantrone Impurity 7
An impurity of Pixantrone which is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non-Hodgkin lymphoma (aNHL). Grades: > 95%. Molecular formula: C21H21N5O5. Mole weight: 423.43.
Pixantrone Impurity 8
An impurity of Pixantrone which is a synthetic, noncardiotoxic aza-anthracenedione analogue with potential antineoplastic activity used to treat aggressive non-Hodgkin lymphoma (aNHL). Grades: > 95%. Molecular formula: C21H21N5O5. Mole weight: 423.43.
Pixantrone Impurity B
An impurity of Pixantrone which intercalates into DNA and induces topoisomerase II-mediated DNA strand crosslinks, resulting in inhibition of DNA replication and tumor cell cytotoxicity. Synonyms: Pixantrone-bis-(2'-N-BOC); Pixantrone-bis-(2'-N-tert-butoxycarbonyl); di-tert-Butyl (((5,10-Dioxo-5,10-dihydrobenzo[g]isoquinoline-6,9-diyl)bis(azanediyl))bis(ethane-2,1-diyl))dicarbamate. Grades: > 95%. CAS No. 144510-94-1. Molecular formula: C27H35N5O6. Mole weight: 525.61.
Pixantrone Impurity D
An impurity of Pixantrone which is a potentially more effective, less cardiotoxic alternative to doxorubicin for patients with aggressive non-Hodgkin lymphoma (aNHL). Grades: > 95%. Molecular formula: C25H23N5O8. Mole weight: 521.49.
Pizotifen
Pizotifen (Pizotyline) is a potent 5-HT 2 receptor antagonist, with a high affinity for 5-HT 1C binding site. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pizotyline; BC-105. CAS No. 15574-96-6. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-B0115.
Pizotifen
Pizotifen is a benzocycloheptene-based drug used as a medicine, primarily as a preventive to reduce the frequency of recurrent migraine headaches. Pizotifen, also called as BC 105, a benzocycloheptathiophene derivative that is a highly selective 5-HT receptor blocking agent both in vivo (on saphenous veins) and in vitro (on saphenous veins and basilar arteries). Uses: Serotonin antagonist structurally related to cyproheptadine. antimigraine; appetite stimulant. Synonyms: 4-(4,5-dihydrobenzo[1,2]cyclohepta[3,4-b]thiophen-10-ylidene)-1-methylpiperidine; BC 105; Pizotifen; Pizotyline; Polomigran; Sandomigran. Grades: 98%. CAS No. 15574-96-6. Molecular formula: C19H21NS. Mole weight: 295.44.
Pizotifen
Pizotifen. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Pizotyline;Piperidine, 4-(9,10-dihydro-4H-benzo[4,5]cyclohepta[1,2-b]thien-4-ylidene)-1-methyl-. Product Category: Thiophenes. Appearance: White to Off-White Solid. CAS No. 15574-96-6. Molecular formula: C19H21NS. Mole weight: 295.44. Purity: 0.98. Product ID: ACM15574966. Alfa Chemistry ISO 9001:2015 Certified.
Pizotifen malate
1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H21NS.C4H6O5. CAS No. 5189-11-7. Prepack ID 12889487-1g. Molecular Weight 429.53. See USA prepack pricing.
Pizotifen malate
Pizotifen malate (Pizotyline malate) is a potent 5-HT 2 receptor antagonist, with a high affinity for 5-HT 1C binding site. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Pizotyline malate; BC-105 malate. CAS No. 5189-11-7. Pack Sizes: 100 mg. Product ID: HY-B0115A.
Pizotifen malate
Pizotifen is a benzocycloheptene-based drug used for the treatment of recurrent migraine headaches. It acts as an antagonist of 5-HT2A and 5HT2C receptors. Synonyms: BC-105; BC 105; BC105. Grades: >98%. CAS No. 5189-11-7. Molecular formula: C19H21NS·C4H6O5. Mole weight: 429.53.
Pizotyline
Serotonin antagonist structurally related to Cyproheptadine. Antimigraine; appetite stimulant. Group: Biochemicals. Alternative Names: 4-(9, 10-Dihydro-4H-benzo[4, 5]cyclohepta[1, 2-b]thien-4-ylidene)-1-methylpiperidine. Grades: Highly Purified. CAS No. 15574-96-6. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
PJ34
PJ34 is a novel and potential PARP inhibitor with potential anticancer activity. PJ34 has a high affinity for PARP-1 (IC(50) = 20 nM). Synonyms: PJ34; PJ-34; PJ 34. CAS No. 344458-15-7. Molecular formula: C17H18ClN3O2. Mole weight: 331.8.
PJ-34 HCL
PJ34 is a potent specific inhibitor of PARPl/2 with IC50 of 110 nM and 86 nM, respectively. Synonyms: PJ-34 HCL; PJ34 HCL; PJ 34 HCL. CAS No. 344458-19-1. Molecular formula: C17H17N3O2. Mole weight: 295.342.
PJ 34 Hydrochloride
A poly adenosine diphosphate-ribose polymerase inhibitor, attenuates chromate-induced nephrotoxicity. Group: Biochemicals. Alternative Names: N- (5, 6-Dihydro-6-oxo-2-phenanthridinyl) -2- (dimethylamino) acetamide. Grades: Highly Purified. CAS No. 344458-15-7. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
PJ-34 Hydrochloride
A potent, water-soluble poly(ADP-ribose) polymerase (PARP) inhibitor (EC50 = 20nM). Inhibits peroxynitrite-induced cell necrosis and displays significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Suppresses cell growth in liver cancer cells. Group: Biochemicals. Alternative Names: N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg, 5mg. US Biological Life Sciences.
Potent, water soluble poly(ADP-ribose) polymerase (PARP) inhibitor. Inhibits peroxynitrite-induced cell necrosis. Shows significant, dose-dependent anti-inflammatory effects in a variety of local inflammation models. Provides cardioprotection by decreasing myocardial infarct size. Shows protective effects in models of stroke. Suppresses cell growth in liver cancer cells. Group: Biochemicals. Alternative Names: N-(6-Oxo-5,6-dihydro-phenanthridin-2-yl)-N,N-dimethylacetamide. HCl. Grades: Highly Purified. CAS No. 344458-15-7. Pack Sizes: 1mg, 5mg, 25mg. US Biological Life Sciences.
Worldwide
PK11195
An isoquinoline carboxamide that acts as a potent ligand for peripheral bezodiazepine receptor (Kd = 20nM). Exhibits anti-inflammatory properties. Binds to monocytes and following lesioning its binding up-regulated in brain macrophages and activated microglia. Shown to enhance the susceptibility of cells to apoptosis induction by DNA damaging agents and can reverse the suppression of apoptosis by Bcl-2. Serves as a ligand of the outer membrane translocator protein and reduces mitochondrial transmembrane potential within 30 minutes of exposure (100uM).CAS Number:85532-75-8. Group: Biochemicals. Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg. Molecular Formula: C??H??ClN?O. US Biological Life Sciences.
Worldwide
PK 11195
PK 11195 (RP 52028) is a ligand of translocator protein (TSPO) , which targets Leishmania chemotherapy, with IC 50 s of 14.2 μM, 8.2 μM, 3.5 μM for L. amazonensis , L. major and L. braziliensis , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RP 52028. CAS No. 85532-75-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19567.
PK 11195
PK 11195 has high affinity for the peripheral benzodiazepine receptor (PBR, TSPO) without binding to other known neurotransmitter receptors. It can also inhibit the human constitutive androstane receptor (hCAR). In Mar 2006, Preclinical for Cancer in United Kingdom was discontinued. Uses: Anticancer. Synonyms: PK11195; PK-11195; PK 11195. 1-(2-Chlorophenyl)-N-methyl-N-(1-methylpropyl)-3-isoquinolinecarboxamide; N-Methyl-N-(1-methylpropyl)-1-(2-chlorophenyl)isoquinoline-3-carboxamide; RP 52028; RP52028; RP-52028. Grades: 98%. CAS No. 85532-75-8. Molecular formula: C21H21ClN2O. Mole weight: 352.86.
PK 11195
Cell-permeable. A Selective peripheral benzodiazepine antagonist. Enhances apoptosis and induces mitochondria cytochrome c release. Inhibits insulin secretion induced by glucose. Also displays anticancer activity. Group: Biochemicals. Alternative Names: 1- (2-Chloro phenyl ) -N- methyl -N- (1- methyl propyl ) -3-isoquinolinecarboxamid e . Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Selective peripheral benzodiazepine antagonist. Apoptosis enhancer. Glucose-induced insulin secretion inhibitor. Induces mitochondria cytochrome c release. Anticancer compound. Antiproliferative. Pharmacological tool in autophagy. Group: Biochemicals. Grades: Highly Purified. CAS No. 85532-75-8. Pack Sizes: 10mg. Molecular Formula: C21H21ClN2O, Molecular Weight: 352.9. US Biological Life Sciences.
Worldwide
PK14105
PK14105, a isoquinoline derivative, could bind to peripheral-type benzodiazepine sites so that it might be a potential radioligand to locate areas of neuronal damage. Uses: Pk14105, a isoquinoline derivative, could bind to peripheral-type benzodiazepine sites so that it might be a potential radioligand to locate areas of neuronal damage. Synonyms: 107257-28-3; PK-14105; PK 14105; PK14105; 3-Isoquinolinecarboxamide,1-(2-fluoro-5-nitrophenyl)-N-methyl-N-(1-methylpropyl)-; N-BUTAN-2-YL-1-(2-FLUORO-5-NITRO-PHENYL)-N-METHYL-ISOQUINOLINE-3-CARBOXAMIDE; ACMC-20maxf. Grades: 95%. CAS No. 107257-28-3. Molecular formula: C21H20FN3O3. Mole weight: 381.40.
Pk 4255
Pk 4255. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 3H-INDOLIUM, 2-[4-[4-(DIMETHYLAMINO)PHENYL]-1,3-BUTADIENYL]-3,3-DIMETHYL-1-PHENYL-, PERCHLORATE;2-(4-P-DIMETHYLAMINOPHENYL-1,3-BUTADIENYL)-3,3-DIMETHYL-1-PHENYLINDOLINIUM PERCHLORATE;2-((1E,3E)-4-[4-(DIMETHYLAMINO)PHENYL]-1,3-BUTADIENYL)-3,3-DIMETHYL-1-P. Product Category: Heterocyclic Organic Compound. CAS No. 43217-07-8. Molecular formula: C28H29ClN2O4. Mole weight: 492.99. Purity: 0.96. IUPACName: 4-[4-(3,3-dimethyl-1-phenylindol-1-ium-2-yl)buta-1,3-dienyl]-N,N-dimethylaniline;perchlorate. Canonical SMILES: CC1(C2=CC=CC=C2[N+](=C1C=CC=CC3=CC=C(C=C3)N(C)C)C4=CC=CC=C4)C.[O-]Cl(=O)(=O)=O. Density: g/cm³. Product ID: ACM43217078. Alfa Chemistry ISO 9001:2015 Certified. Categories: AKOS000813950.
PK 44 phosphate
PK 44 phosphate. Group: Biochemicals. Grades: Purified. CAS No. 1017682-66-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
PK 44 phosphate
PK 44 phosphate is a potent inhibitor of dipeptidyl peptidase IV (DPP-IV) with an IC50 value of 15.8 nM, which displays >1000-fold selectivity for DPP-IV over DPP-8 and DPP-9. Synonyms: PK-44 phosphate; PK44 phosphate; (3R)-3-Amino-4-(6,7-difluoro-1H-indazol-3-yl)-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-1-butanone phosphate; 1-Butanone, 3-amino-4-(6,7-difluoro-1H-indazol-3-yl)-1-[5,6-dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-, (3R)-, phosphate (1:1); (R)-3-amino-4-(6,7-difluoro-1H-indazol-3-yl)-1-(3-(trifluoromethyl)-5,6-dihydro-[1,2,4]triazolo[4,3-a]pyrazin-7(8H)-yl)butan-1-one phosphate. Grades: ≥98% by HPLC. CAS No. 1017682-66-4. Molecular formula: C17H16F5N7O.H3PO4. Mole weight: 527.34.
PK7242 maleate
PK7242 is an inducer of reactivation of mutant p53 in cancer cells. Synonyms: 2-[4-(4-fluorophenyl)-3-pyrrol-1-ylpyrazol-1-yl]-N,N-dimethylethanamine maleate. Grades: ≥95%. CAS No. 1446352-68-6. Molecular formula: C17H19FN4·C4H4O4. Mole weight: 414.4.
Heat-stable protein kinase inhibitor (PKI) peptide sequence (14-22) that has been myristoylated at the N-terminus, enhancing its cell-permeability. The non-myristoylated version of this peptide is a highly specific inhibitor (Ki=6nM) of cAMP-dependent protein kinase. Group: Biochemicals. Alternative Names: Myr-N-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH?. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
PKA inhibitor fragment (6-22) amide
PKA inhibitor fragment (6-22) amide is a synthetic peptide inhibitor of cAMP-dependent protein kinase (PKA) (Ki = 2.5 nM) derived from the heat-stable PKA inhibitor protein PKI. It is the shortest synthetic PKI peptide that retains high potency for PKA inhibition. Synonyms: PKI (6-22) amide; H-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2; L-threonyl-L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-seryl-glycyl-L-arginyl-L-threonyl-glycyl-L-arginyl-L-arginyl-L-asparagyl-L-alanyl-L-isoleucinamide; Tyadfiasgrtgrrnai-nh2; Protein Kinase A Inhibitor Fragment 6-22 amide. Grades: ≥95%. CAS No. 121932-06-7. Molecular formula: C80H130N28O24. Mole weight: 1868.08.
PKA inhibitor fragment (6-22) amide acetate
PKA Inhibitor Fragment (6-22) amide acetate is a synthetic peptide inhibitor of cAMP-dependent protein kinase (PKA) (Ki = 2.5 nM), derived from the heat-stable PKA inhibitor protein PKI. It is the shortest synthetic PKI peptide that retains high potency for PKA inhibition. Synonyms: H-Thr-Tyr-Ala-Asp-Phe-Ile-Ala-Ser-Gly-Arg-Thr-Gly-Arg-Arg-Asn-Ala-Ile-NH2.CH3CO2H; L-threonyl-L-tyrosyl-L-alanyl-L-alpha-aspartyl-L-phenylalanyl-L-isoleucyl-L-alanyl-L-seryl-glycyl-L-arginyl-L-threonyl-glycyl-L-arginyl-L-arginyl-L-asparagyl-L-alanyl-L-isoleucinamide acetic acid. Grades: ≥95%. Molecular formula: C82H134N28O26. Mole weight: 1928.11.
PKC (19-36)
PKC (19-36). Group: Biochemicals. Grades: Purified. CAS No. 113731-96-7. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
PKC (19-36)
PKC (19-36) is a pseudosubstrate peptide inhibitor of protein kinase C (IC50 = 0.18 μM). Synonyms: Gly-Arg-Pro-Arg-Thr-Ser-Ser-Phe-Ala-Glu-Gly. Grades: >97%. CAS No. 113731-96-7. Molecular formula: C93H159N35O24. Mole weight: 2151.48.
PKC-9
PKC-9 is a potent and selective inhibitor of PKCζ with IC50 value of 5.18 nM. Synonyms: 4-[3-[7-(4-methyl-1-piperazinyl)-1H-benzimidazol-2-yl]-1H-indazol-6-yl]-benzenamine. Grades: ≥95%. CAS No. 1132609-87-0. Molecular formula: C25H25N7. Mole weight: 423.51.
PKC Activator VII, CGK062 (Protein Kinase C Activator VII)
A cell permeable coumarin-containing compound that is shown to activate PKCalpha activity and induce cellular PKCalpha membrane translocation (Effective conc. 12.5 to 50uM) as well as PKCalpha-mediated signaling events. Effectively affects the viability of CRT-dependent cancer cells (IC50 = 1.62 to 18.6uM; 48h) in vitro and suppresses PC3-derived tumor expansion in mice (50 & 100mg/kg/day; i.p) in vivo, while exhibiting little cytotoxicity toward WI38 normal fibroblasts. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 2mg. Molecular Formula: C??H??O?, Primary Target IC50: 12.2uM. US Biological Life Sciences.
Worldwide
PKCα (C2-4) Inhibitor Peptide
PKCα (C2-4) inhibitor peptide is an inhibitor of PKC activity in HepG2 cells stimulated with calcium and pancreastatin when applied at 10 μM. Synonyms: Protein Kinase Cα (C2-4) Inhibitor Peptide. Grades: ≥95%. Molecular formula: C47H74N14O17. Mole weight: 1107.2.
PKC β pseudosubstrate
PKC β pseudosubstrate. Group: Biochemicals. Grades: Purified. CAS No. 172308-76-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
PKC β pseudosubstrate
PKC β pseudosubstrate, a selective cell-permeable peptide inhibitor of protein kinase C (IC50 ~ 0.5 μM), consists of amino acids 19-31 of PKC pseudosubstrate domain linked by a disulphide bridge to a cell permeabilisation Antennapedia domain vector peptide. Synonyms: PKC beta pseudosubstrate; Protein kinase C beta pseudosubstrate; H-Cys(1)-Arg-Gln-Ile-Lys-Ile-Trp-Phe-Gln-Asn-Arg-Arg-Met-Lys-Trp-Lys-Lys-OH.H-Cys(1)-Arg-Phe-Ala-Arg-Lys-Gly-Ala-Leu-Arg-Gln-Lys-Asn-Val-OH; L-cysteinyl-L-arginyl-L-glutaminyl-L-isoleucyl-L-lysyl-L-isoleucyl-L-tryptophyl-L-phenylalanyl-L-glutaminyl-L-asparagyl-L-arginyl-L-arginyl-L-methionyl-L-lysyl-L-tryptophyl-L-lysyl-L-lysine (1->1')-disulfide compound with L-cysteinyl-L-arginyl-L-phenylalanyl-L-alanyl-L-arginyl-L-lysyl-glycyl-L-alanyl-L-leucyl-L-arginyl-L-glutaminyl-L-lysyl-L-asparagyl-L-valine. Grades: >98%. CAS No. 172308-76-8. Molecular formula: C177H294N62O38S3. Mole weight: 3994.84.
PKCε Inhibitor Peptide
PKC? inhibitor peptide is a synthetic peptide that inhibits the translocation of PKC? to intracellular membranes, blocking activation. PKC? inhibitor peptide is commonly used in cells to evaluate the role of PKC? in various cellular responses. Synonyms: Protein Kinase C? Inhibitor Peptide; ?V1-2. Grades: ≥95%. CAS No. 182683-50-7. Molecular formula: C37H65N9O13. Mole weight: 844.
PKC-IN-1
PKC-IN-1 has been found to be a PKCβII inhibitor that probably has biological activity in antineoplastic studies. Ki: 14.9 nM. Uses: Pkc-in-1 has been found to be a pkcβii inhibitor that probably has biological activity in antineoplastic studies. Synonyms: PKC-IN-1; SCHEMBL3325504; CS-4284; DA-48103; HY-16903; CS 4284; DA 48103; HY 16903; CS4284; DA48103; HY16903. Grades: 98%. CAS No. 1046787-18-1. Molecular formula: C25H37FN8O2. Mole weight: 500.61.
PKC/PKD-IN-1
PKC/PKD-IN-1 (Compound 13C) is an orally active dual protein kinase C/D ( PKC/PKD ) inhibitor with an IC 50 value of 0.6 nM for PKD1. PKC/PKD-IN-1 can attenuate high-salt diet-induced cardiac hypertrophy and can be used in the study of heart failure [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1071135-06-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-128142.
PKCTheta-IN-2
PKCTheta-IN-2 (compound 14) is a potent and selective PKCθ inhibitor with an IC 50 of 0.25 nM. PKCTheta-IN-2 shows good selectivity over a wide range of kinases, including the PKC subfamily (30 kinases). PKCTheta-IN-2 inhibits the IL-2 production in a mouse ( IC 50 of 682 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1810742-60-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164756.