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| Product | Description | |
|---|---|---|
| Primeverose | Primeverose is a natural compound which can be isolated from the genus Primula. Alternative Names: 6-(b-D-Xylosido)-D-glucose; 6-O-β-D-Xylopyranosyl-D-glucose; Xyl(b1-6)aldehydo-Glc; 6-(β-D-Xylosido)-D-glucose; (2R,3S,4R,5R)-2,3,4,5-Tetrahydroxy-6-(((2S,3R,4S,5R)-3,4,5-trihydroxytetrahydro-2H-pyran-2-yl)oxy)hexanal. Grades: 98%. CAS No. 26531-85-1. Molecular formula: C11H20O10. Mole weight: 312.27. |  |
| Primidone | Primidone is the orally active inhibitor for TRPM3 (IC50 = 0.6 μM), RIP kinase and voltage-gated sodium channel, and the antagonist for GABA receptor. Primidone can be used as the analgesic and anticonvulsant agent[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 125-33-7. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg. Product ID: HY-B0339. |  |
| Primidone | Anticonvulsant. Group: Biochemicals. Alternative Names: 5-Ethyldihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione; Liskantin; Mylepsinum; Mysoline; Resimatil; Sertan. Grades: Highly Purified. CAS No. 125-33-7. Pack Sizes: 10g. US Biological Life Sciences. |  Worldwide |
| Primidone-d5 | Anticonvulsant. Group: Biochemicals. Alternative Names: 5-(Ethyl-d5)dihydro-5-phenyl-4,6(1H,5H)-pyrimidinedione; Liskantin-d5; Mylepsinum-d5; Mysoline-d5; Resimatil-d5; Sertan-d5. Grades: Highly Purified. CAS No. 73738-06-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Primidone EP impurity A | Primidone EP impurity A. Uses: For analytical and research use. CAS No. 7206-76-0. Molecular formula: C11H14N2O2. Mole weight: 206.25. Catalog: APB7206760. |  |
| Primidone EP impurity C | Primidone EP impurity C. Uses: For analytical and research use. CAS No. 90-26-6. Molecular formula: C10H13NO. Mole weight: 163.22. Catalog: APB90266. | |
| Primidone EP impurity D | Primidone EP impurity D. Uses: For analytical and research use. CAS No. 80544-75-8. Molecular formula: C11H12N2O. Mole weight: 188.23. Catalog: APB80544758. | |
| Primidone EP impurity E | Primidone EP impurity E. Uses: For analytical and research use. CAS No. 90-27-7. Molecular formula: C10H12O2. Mole weight: 164.2. Catalog: APB90277. | |
| Primidone EP impurity F | Primidone EP impurity F. Uses: For analytical and research use. CAS No. 1189504-46-8. Molecular formula: C21H24N2O2. Mole weight: 336.44. Catalog: APB1189504468. | |
| Primidone impurity 2 | Primidone impurity 2. Uses: For analytical and research use. CAS No. 2753-74-4. Molecular formula: C12H12N2O2S. Mole weight: 248.3. Catalog: APB2753744. | |
| Primidone Related Compound A | Primidone Related Compound A. Uses: For analytical and research use. CAS No. 7206-76-0. Mole weight: 206.24. Catalog: AP7206760. | |
| Primidone Related Compound C | Primidone Related Compound C. Uses: For analytical and research use. CAS No. 90-26-6. Mole weight: 163.22. Catalog: AP90266. | |
| Primocarcin | Primocarcin is an antibiotic produced by Nocardia fukayea 11-41. Antibacterial effect is weak; inoculated with Ehrlich ascites cancer mice intraperitoneally given 0.125-0. 5mg / mouse/day, ascites does not increase, and survival time is more than doubled. For Sarcoma-180, given the same dose, the same effect was achieved. Alternative Names: 5-(Acetylamino)-4-oxo-5-hexenamide; 4-Acetamido-4-penten-3-one-1-carboxamide. CAS No. 3750-26-3. Molecular formula: C8H12N2O3. Mole weight: 184.19. | |
| prim-O-Glucosylangelicain | prim-O-Glucosylangelicain is isolated from the roots of Cimicifuga foetida L. Alternative Names: (S)7-[(beta-D-Glucopyranosyloxy)methyl]-2,3-dihydro-4-hydroxy-2-(1-hydroxy-1-methylethyl)-5H-furo[3,2-g][1]benzopyran-5-one. Grades: >95%. CAS No. 85889-15-2. Molecular formula: C21H26O11. Mole weight: 454.42. | |
| Prim-O-glucosylcimifugin | Prim-O-glucosylcimifugin. Group: Biochemicals. Grades: Plant Grade. CAS No. 80681-45-4. Pack Sizes: 20mg. Molecular Formula: C22H28O11, Molecular Weight: 468.45. US Biological Life Sciences. | Worldwide |
| Primuline | Primuline. Alternative Names: Primuline; Primuline sodium salt. Grades: Dye content >60%. CAS No. 8064-60-6. Molecular formula: C21H14N3O3S3Na. Mole weight: 475.54. | |
| Primycin | Primycin is a macrolide antibiotic produced by Str. primycini. It is active against gram-positive bacteria, mycobacteria and protozoa. Alternative Names: Ebrimycin; Primycin A1. CAS No. 47917-41-9. Molecular formula: C55H103N3O17. Mole weight: 1078.4. | |
| Prinaberel | Prinaberel (ERB-041) is a potent and selective estrogen receptor (ER) β agonist with IC50s of 5.4, 3.1 and 3.7 nM for human, rat and mouse ERβ, respectively. Prinaberel displays >200-fold selectivity for ERβ over ERα. Prinaberel is a potent skin cancer chemopreventive agent that acts by dampening the WNT/β-catenin signaling pathway. Prinaberel induces ovarian cancer apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ERB-041. CAS No. 524684-52-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14933. | |
| Prinomastat | Prinomastat (AG3340) is a broad spectrum, potent, orally active metalloproteinase (MMP) inhibitor with IC50s of 79, 6.3 and 5.0 nM for MMP-1, MMP-3 and MMP-9, respectively. Prinomastat inhibits MMP-2, MMP-3, MMP-13 and MMP-9 with Kis of 0.05 nM, 0.3 nM, 0.03 nM and 0.26 nM, respectively. Prinomastat crosses blood-brain barrier. Antitumor avtivity[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AG3340; KB-R9896. CAS No. 192329-42-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-12170. | |
| Prinomastat | Prinomastat is a synthetic hydroxamic acid derivative with potential antineoplastic activity. Prinomastat inhibits matrix metalloproteinases (MMPs) (specifically, MMP-2, 9, 13, and 14), thereby inducing extracellular matrix degradation, and inhibiting angiogenesis, tumor growth and invasion, and metastasis. As a lipophilic agent, prinomastat crosses the blood-brain barrier. Uses: Matrix metalloproteinase inhibitors. Alternative Names: AG3340; AG-3340; AG 3340; KBR-9896; KBR 9896; KBR9896. CAS No. 192329-42-3. Molecular formula: C18H21N3O5S2. Mole weight: 423.50. | |
| Prionidipene A | Prionidipene A, a promising chemical compound, exhibits therapeutic potential in treating neurological disorders including Alzheimer's disease. This inhibitor of the beta-site amyloid precursor protein cleaving enzyme curtails the production of amyloid beta peptides, an established hallmark of Alzheimer's disease. Interestingly, research proposes that Prionidipene A reduces amyloid beta levels in the brain, which in turn has therapeutic implications. Moreover, improved cognitive function was noted, suggesting that this compound could be a pivotal stepping stone in developing novel therapeutics for Alzheimer's disease. Grades: > 95%. CAS No. 2199455-72-4. Molecular formula: C21H26O3. Mole weight: 326.43. | |
| Prion Protein (106-126) (human) (scrambled) | Prion Protein (106-126) (human) (scrambled) is a scrambled sequence of human prion protein (106-126), which is an important control for studying the biological activity of prion protein peptides. According to circular dichroism analysis, the scrambled PrP 106-126 shows a random coil structure without aggregation, and is completely degraded after incubation with proteinase K and pronase for 30 minutes at 37°C. Alternative Names: H-Asn-Gly-Ala-Lys-Ala-Leu-Met-Gly-Gly-His-Gly-Ala-Thr-Lys-Val-Met-Val-Gly-Ala-Ala-Ala-OH; L-asparagyl-glycyl-L-alanyl-L-lysyl-L-alanyl-L-leucyl-L-methionyl-glycyl-glycyl-L-histidyl-glycyl-L-alanyl-L-threonyl-L-lysyl-L-valyl-L-methionyl-L-valyl-glycyl-L-alanyl-L-alanyl-L-alanine; Prion Protein Fragment 106-126 Scrambled Human; PrP (106-126) (human) (scrambled). Grades: ≥90%. CAS No. 150469-23-1. Molecular formula: C80H138N26O24S2. Mole weight: 1912.24. | |
| Prion Protein Fragment 106-126 Human | Prion Protein Fragment 106-126 Human. Uses: For analytical and research use. CAS No. 148439-49-0. Mole weight: 1912.24. Catalog: AP148439490. | |
| Prion Protein Fragment 106-126 Scrambled Human | Prion Protein Fragment 106-126 Scrambled Human. Uses: For analytical and research use. CAS No. 150469-23-1. Mole weight: 1912.24. Catalog: AP150469231. | |
| Priplast Polyester polyols | Priplast Polyester polyols. |  |
| Pripol Dimer Diol | Pripol Dimer Diol. | |
| Pripol Dimer fatty acid | Pripol Dimer fatty acid. | |
| Pristane | Pristane. CAS No: 1921-70-6 |  Sarchem Laboratories New Jersey NJ |
| Pristane | Pristane (Norphytane) is a naturally occurring hydrocarbon oil found in small quantities in many plants, in various marine organisms, and as the most active component of mineral oil[1]. Pristane is a non-antigenic adjuvant, and induces MHC class II-restricted, arthritogenic T cells in the rat[2]. Uses: Scientific research. Category: Natural products. Alternative Names: Norphytane. CAS No. 1921-70-6. Pack Sizes: 1 mL; 10 mM * 1 mL in DMSO; 5 mL; 10 mL; 25 mL; 50 mL; 100 mL. Product ID: HY-N7819. | |
| Pristane | Pristane is a naturally saturated terpenoid alkane obtained primarily from shark liver oil. Pristane is a non-antigenic adjuvant that induces MHC class II-restricted, arthritogenic T cells in the rat. It is used as a lubricant, transformer oil, immunologic adjuvant, anti-corrosion agent, biological marker, plasmacytoma inducer, and in the production of monoclonal antibodies. Alternative Names: Pentadecane, 2,6,10,14-tetramethyl-; Bute hydrocarbon; Norphytan; Norphytane; NSC 114852; Pristan. Grades: ≥95%. CAS No. 1921-70-6. Molecular formula: C19H40. Mole weight: 268.52. | |
| Pristanic acid | Pristanic acid is an endogenous metabolite present in Blood that can be used for the research of Alpha Methylacyl CoA Racemase Deficiency and Zellweger Syndrome[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1189-37-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-113024. | |
| Pristanic acid solution,mixture of isomers,ethanol solution | Pristanic acid solution,mixture of isomers,ethanol solution. Alternative Names: acide pristanique; (2S,6R,10R)-2,6,10,14-tetramethylpentadecanoic acid; 2,6,10,14-tetramethyl-pentadecanoic acid; Pristaninsaeure; 2,6,10,14-Tetramethyl-pentadecansaeure; Pristanic acid solution; 2,6,10,14-Tetramethylpentadecanoic acid; 2,6,10,14-tetramet. CAS No. 1189-37-3. Purity: 96%. Product ID: ACM1189373. Molecular formula: C19H38O2. Mole weight: 298.50. IUPAC Name: 2,6,10,14-tetramethylpentadecanoic acid. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Pristimerin | Source from herb of Tripterygium wilfordii Hook.f. Treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell characteristics and EMT in cancer cells, which justifies the potential use of Pristimerin as a practical chemopreventive approach for patients with PCa. The mechanistic understanding of the antitumor activity of Pristimerin could facilitate in vivo efficacy studies of Pristimerin for pancreatic cancer. Uses: Anticancer. Alternative Names: (9b,13a,14b,20a)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tertraen-29-oic acid methyl ester. Grades: 98%. CAS No. 1258-84-0. Molecular formula: C30H40O4. Mole weight: 464.64. | |
| Pristimerin | Pristimerin. Group: Biochemicals. Alternative Names: (9 β,13α,14 β,20α)-3-Hydroxy-9,13-dimethyl-2-oxo-24,25,26-trinoroleana-1(10),3,5,7-tetraen-29-oic Acid Methyl Ester; 3-Hydroxy-2-oxo-24-Nor-D:A-friedooleana-1(10),3,5,7-tetraen-29-oic Acid Methyl Ester; (20α)-3-Hydroxy-2-oxo-D:A-friedo-24-noroleana-1(10),3,5,7-tetraen-29-oic Acid Methyl Ester; (2R, 4aS, 6aS, 12bR, 14aS, 14bR)-1, 2, 3, 4, 4a, 5, 6, 6a, 11, 12b, 13, 14, 14a, 14b-Tetradecahydro-10-hydroxy-2, 4a, 6a, 9, 12b, 14a-hexamethyl-11-oxo-2-picenecarboxylic Acid Methyl Ester; [2R-(2α,4a β,6a β,12b β,14aα,14b β)]-1, 2, 3, 4, 4a, 5, 6, 6a, 11, 12b, 13, 14, 14a, 14b-Tetradecahydro-10-hydroxy-2, 4a, 6a, 9, 12b, 14a-hexamethyl-11-oxo-2-picenecarboxylic Acid, Methyl Ester; Celastrol Methyl Ester; NSC 99281. Grades: Highly Purified. CAS No. 1258-84-0. Pack Sizes: 5mg. Molecular Formula: C30H40O4, Molecular Weight: 464.64. US Biological Life Sciences. | Worldwide |
| Pristimerin | Pristimerin is a potent and reversible monoacylglycerol lipase (MGL) inhibitor with an IC50 of 93 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Celastrol methyl ester. CAS No. 1258-84-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N1937. | |
| Pristinamycin | 25mg Pack Size. Group: Antibiotics, Bioactive Small Molecules. Formula: C73H89N11O17. CAS No. 270076-60-3. Prepack ID 31084931-25mg. Molecular Weight 1392.55. See USA prepack pricing. |  |
| Pristinamycin | Pristinamycin is a complex of antibiotics produced by streptomyces pristinaespiralis, containing two components Pristinamycin IA and Pristinamycin IIA. Pristinamycin IA is a macrolide, and Pristinamycin IIA (streptogramin A) is a depsipeptide. Pristinamycin has been indicated for the treatment of MRSA. Alternative Names: Pyostacine; Stafac; Pristinamycine; Staphylomycin; Virginiamycin. CAS No. 270076-60-3. Molecular formula: C73H89N11O17. Mole weight: 1392.55. | |
| Pristinamycin IA | Pristinamycin IA (Mikamycin B) is a cycle-peptidic macrolactone antibiotic. Pristinamycin IA is a substrate of P-glycoprotein and inhibits its function. Pristinamycin IA is active against StaphyloEoccus and Srreptococcus[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Mikamycin B; Mikamycin IA. CAS No. 3131-3-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-A0279A. | |
| Pristinamycin IA-[13C5,15N] | Pristinamycin IA-[13C5,15N] is the labelled analogue of Pristinamycin IA. Pristinamycin IA is a depsipeptide antibiotic co-produced with ostreogrycin A, together used as a synergistic mixture; also known as ostreogrycin B and streptogramin B among other synonyms. Alternative Names: [13C5,15N]-Pristinamycin IA. Molecular formula: C40[13C]5H54N7[15N]O10. Mole weight: 872.91. | |
| Pristinamycin IA-d6 | An isotope labelled Pristinamycin IA. Pristinamycin IA is an antibiotic cyclic peptide. It is a member of the streptogramin B group of antibiotics and one component of pristinamycin. Grades: 95% by HPLC; 98% atom D. Molecular formula: C45H48N8O10D6. Mole weight: 873.02. | |
| Pristinamycin IB | Pristinamycin IB is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Alternative Names: Ostreogrycin B2; Efepristin. CAS No. 57206-54-9. Molecular formula: C44H52N8O10. Mole weight: 852.93. | |
| Pristinamycin IC | Pristinamycin IC is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Alternative Names: Vernamycin B gamma. CAS No. 28979-74-0. Molecular formula: C44H52N8O10. Mole weight: 852.93. | |
| Pristinamycin IIA | Pristinamycin IIA is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Uses: Anti-bacterial agents. Alternative Names: virginiamycin M1; Streptogramin A; Mikamycin A; Ostreogrycin a. Grades: ≥ 95%. CAS No. 21411-53-0. Molecular formula: C28H35N3O7. Mole weight: 525.59. | |
| Pristinamycin IIA-d4 | An isotope labelled Pristinamycin IIA.Pristinamycin IIA is a macrolide antibiotic. It is a member of the streptogramin A group of antibiotics and one component of pristinamycin. Grades: 95% by HPLC; 98% atom D. Molecular formula: C28H31N3O7D4. Mole weight: 529.63. | |
| Pristinamycin IIB | Pristinamycin IIB is an ester peptide antibiotic produced by Str. pristinaespiralis 5647 (NRRL 2958). Activity against gram-positive bacteria. Alternative Names: Volpristin; Virginiamycin M2. CAS No. 21102-49-8. Molecular formula: C28H37N3O7. Mole weight: 527.61. | |
| Pristine Multilayered Graphene Suspension | Pristine Multilayered Graphene Suspension. | |
| Pristine Multi-walled Carbon Nanotubes | Pristine Multi-walled Carbon Nanotubes. Purity: 99%. | |
| Pristine MWCNT | Pristine MWCNT. CAS No. 308068-56-6. Purity: >95% (MWCNT). | |
| Pristine Single | Pristine Single. | |
| Pristine SWCNT | Pristine SWCNT. Purity: 99%. | |
| Pritelivir | Pritelivir (AIC316), an inhibitor of the viral helicase-primase complex, exhibits antiviral activity in vitro and in animal models of herpes simplex virus (HSV) infection. Pritelivir is active against herpes simplex virus types 1 and 2 (HSV-1 and HSV-2) with the IC50 of 0.02 μM against HSV1-2[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AIC316; BAY 57-1293. CAS No. 348086-71-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15303. | |
| Pritelivir mesylate | Pritelivir mesylate is a potent helicase primase inhibitor that inhibits HSV replication. Pritelivir is active against both types of herpes simplex virus (HSV-1 and HSV-2). Alternative Names: Pritelivir (mesylate); BAY 57-1293 Methanesulfonate Salt; Pritelivir methanesulfonate. Grades: 98% by HPLC. CAS No. 1428333-96-3. Molecular formula: C19H22N4O6S3. Mole weight: 498.6. | |
| Pritumumab | Pritumumab is a natural human IgG1kappa mAb originally isolated from a regional draining lymph node of a patient with cervical carcinoma. Pritumumab recognizes vimentin expressing on the cell surface of the malignant tumor. Pritumumab can be used for glioblastoma research[1][2]. Uses: Scientific research. Category: Inhibitory antibodies. CAS No. 499212-74-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99806. | |
| PRLX-93936 | PRLX-93936 is a molecular Glues that binds to and reprograms the TRIM21 ubiquitin ligase to degrade nuclear pore complexes. PRLX-93936 binds to TRIM21, forms a ternary complex with TRIM21 and NUP98, and mediates the ubiquitination and proteasomal degradation of NUP98 and other nuclear pore complex proteins. PRLX-93936 induces the loss of short-lived cytoplasmic mRNA transcripts, triggers cancer cell apoptosis (Apoptosis), and inhibits the activated Ras pathway. PRLX-93936 inhibits HIF-1 under hypoxic conditions (IC50 = 0.09 μM in cell-based reporter gene assay). PRLX-93936 suppresses tumor growth in mouse models and improves survival rates in mouse models of multiple myeloma. PRLX-93936 is applicable to research related to pancreatic cancer and multiple myeloma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 903499-49-0. Pack Sizes: 1 mg; 5 mg. Product ID: HY-119264. | |
| PRLX-93936 dihydrochloride | PRLX-93936 dihydrochloride is a molecular Glues that binds to and reprograms the TRIM21 ubiquitin ligase to degrade nuclear pore complexes. PRLX-93936 dihydrochloride binds to TRIM21, forms a ternary complex with TRIM21 and NUP98, and mediates the ubiquitination and proteasomal degradation of NUP98 and other nuclear pore complex proteins. PRLX-93936 dihydrochloride induces the loss of short-lived cytoplasmic mRNA transcripts, triggers cancer cell apoptosis (Apoptosis), and inhibits the activated Ras pathway. PRLX-93936 dihydrochloride inhibits HIF-1 under hypoxic conditions (IC50 = 0.09 μM in cell-based reporter gene assay). PRLX-93936 dihydrochloride suppresses tumor growth in mouse models and improves survival rates in mouse models of multiple myeloma. PRLX-93936 dihydrochloride is applicable to research related to pancreatic cancer and multiple myeloma[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1094210-96-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-119264A. | |
| PRMT5:MEP50 PPI | PRMT5:MEP50 PPI is a novel PRMT5:MEP50 protein-protein interaction (PRMT5:MEP50 PPI) inhibitor, shows anti-tumor activity and anti-proliferative activity of lung and prostate cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3031536-71-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151576. | |
| PRMT9-IN-1 | PRMT9-IN-1 is a PRMT9 inhibitor. PRMT9-IN-1 can be used in the research of hematological cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1134334-55-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W280124. | |
| PRN1371 | PRN1371 is an irreversible covalent FGFR1-4 kinase inhibitor. Alternative Names: 6-(2,6-dichloro-3,5-dimethoxyphenyl)-2-(methylamino)-8-[3-(4-prop-2-enoylpiperazin-1-yl)propyl]pyrido[2,3-d]pyrimidin-7-one. CAS No. 1802929-43-6. Molecular formula: C26H30Cl2N6O4. Mole weight: 561.46. | |
| PRN1371 | PRN1371 is a highly selective and potent FGFR1-4 and CSF1R inhibitor with IC50s of 0.6, 1.3, 4.1, 19.3 and 8.1 nM for FGFR1, FGFR2, FGFR3, FGFR4 and CSF1R, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802929-43-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101768. | |
| PRN694 | PRN694 is an irreversible, highly selective and potent covalent interleukin-2-inducible T-cell kinase (ITK) and resting lymphocyte kinase (RLK) dual inhibitor with IC50s of 0.3 nM and 1.4 nM, respectively. PRN694 exhibits extended target residence time on ITK and RLK, enabling durable attenuation of effector cells in vitro and in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1575818-46-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12680. | |
| PRO-6E | PRO-6E is an oral active PROTAC based on Cereblon ligand, and induces the degradation of MET with maximum degradation of 81.9% at 1 μM in MKN-45 cells. PRO-6E inhibits tumor growth in vivo and in vitro. PRO-6E induces cell apoptosis and induces cell arrest (Sturcture Note:(Blue: Cereblon ligand (HY-103596), Black: linker?Pink: ALK/c-Met inhibitor Crizotinib (HY-50878))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2353493-69-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160506. | |
| PRO-6E | PRO-6E demonstrates tumor growth inhibition both in vivo and in vitro, alongside inducing cell apoptosis and cell cycle arrest. Category: Active pharmaceutical ingredients. CAS No. 2353493-69-1. Product ID: API2353493691. Molecular formula: C42H44Cl2FN7O7. Mole weight: 848.75. |  |
| Proadifen hydrochloride | Proadifen (SKF-525A) hydrochloride is a non-competitive Cytochrome P450 inhibitor with an IC50 value of 19 μM. Proadifen hydrochloride reduces monoamine oxidase A (MAO-A) activity and reverses the antidepressantlike behavioral effect of Imipramine (HY-B1490A) and Desipramine (HY-B1272A) in rats. Proadifen hydrochloride also reduces N, N-dimethyltryptamine (DMT) metabolism in liver microsomes and inhibits N-demethylationand Acridone (HY-W007771) formation. Proadifen hydrochloride augments Lipopolysaccharide (LPS) (HY-D1056)-induced fever and exacerbates Prostaglandin E2 (PGE2) (HY-101952) levels in the rat. Proadifen hydrochloride is promising for research of metabolism-related deseases, ovarian carcinoma, inflammation and dopamine neurons-related deseases[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SKF-525A; U-5446; RP-5171. CAS No. 62-68-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg. Product ID: HY-B1311. | |
| Proadrenomedullin (1-20), human | Proadrenomedullin (1-20), human is a potent hypotensive and catecholamine release-inhibitory peptide released from chromaffin cells. Proadrenomedullin (1-20) inhibits catecholamine secretion in PC12 pheochromocytoma cells (IC50 ? 350 nM) by suppressing Na+/Ca2+ influx and blocking desensitization. Proadrenomedullin (1-20), human specifically acts on nicotinic cholinergic receptors in a non competitive manner. Proadrenomedullin (1-20), human can be used for research on conditions such as hypertension[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ProAM N20, Human; PAMP-20, human. CAS No. 150238-87-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1831. | |
| Proadrenomedullin (1-20) (rat) | Proadrenomedullin (1-20) (rat). Alternative Names: PAMP (rat); H-Ala-Arg-Leu-Asp-Thr-Ser-Ser-Gln-Phe-Arg-Lys-Lys-Trp-Asn-Lys-Trp-Ala-Leu-Ser-Arg-NH2; L-Alanyl-L-arginyl-L-leucyl-L-α-aspartyl-L-threonyl-L-seryl-L-seryl-L-glutaminyl-L-phenylalanyl-L-arginyl-L-lysyl-L-lysyl-L-tryptophyl-L-asparaginyl-L-lysyl-L-tryptophyl-L-alanyl-L-leucyl-L-seryl-L-argininamide. Grades: ≥95% by HPLC. CAS No. 167699-60-7. Molecular formula: C111H177N37O28. Mole weight: 2477.82. | |
| Proadrenomedullin (45-92), human | Proadrenomedullin (45-92), human is an intermediate region fragment of proadrenomedullin (MR-proADM) containing 45-92 amino acids. Alternative Names: Glu-Leu-Arg-Met-Ser-Ser-Ser-Tyr-Pro-Thr-Gly-Leu-Ala-Asp-Val-Lys-Ala-Gly-Pro-Ala-Gln-Thr-Leu-Ile-Arg-Pro-Gln-Asp-Met-Lys-Gly-Ala-Ser-Arg-Ser-Pro-Glu-Asp-Ser-Ser-Pro-Asp-Ala-Ala-Arg-Ile-Arg-Val. Grades: ≥95%. CAS No. 166798-69-2. Molecular formula: C215H359N67O73S2. Mole weight: 5114.76. | |
| Proadrenomedullin (45-92), human | Proadrenomedullin (45-92), human, a mid-regional fragment of proadrenomedullin (MR-proADM), comprises amino acids 45-92 of pre-proADM. Proadrenomedullin (45-92), human has a longer half-life, is relatively stable and is produced in equimolar amounts to adrenomedullin (ADM), making it a surrogate for plasma levels of ADM gene products[1][2]. Uses: Scientific research. Category: Peptides. CAS No. 166798-69-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1838. | |
| Pro-Ala-Trp-Phe-Arg | Pro-Ala-Trp-Phe-Arg. Alternative Names: mut3-FITC. | |
| Proanthocyanidin A4 | Proanthocyanidin A4 is a Procyanidin isolated from the root of E. sinica. It shows anti-inflammatory effects. Alternative Names: 8,14-Methano-2H,14H-1-benzopyrano[7,8-d][1,3]benzodioxocin-3,5,11,13,15-pentol, 2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-, (2S,3R,8S,14R,15R)-; (2S,3R,8S,14R,15R)-2,8-bis(3,4-dihydroxyphenyl)-3,4-dihydro-2H,14H-8,14-methanobenzo[7,8][1,3]dioxocino[4,5-h]chromene-3,5,11,13,15-pentol; (+)-Epicatechin-(4β-8,2β-O-7)-(-)-catechin, Proanthocyanidin A4. Grades: ≥95%. CAS No. 111466-29-6. Molecular formula: C30H24O12. Mole weight: 576.51. | |
| Proanthocyanidins | Proanthocyanidin (Procyanidin) are a class of polyphenolic that are widely distributed in higher plants, consisted of an electrophilic flavanyl unit. Proanthocyanidin can be used as antioxidant and anti-cancers agent. Proanthocyanidin also exhibit anti-inflammatory, cardioprotective, antibacterial and antifungal properties, which can be used in the treatment of chronic venous insufficiency, capillary fragility, sunburn and retinopathy.[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 20347-71-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0794. | |
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