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| Product | Description | |
|---|---|---|
| Rimeporide-15N3 Hydrochloride | Rimeporide-15N3 Hydrochloride. Group: Biochemicals. Alternative Names: N- (Aminoiminomethyl) -2-methyl-4, 5-bis (methylsulfonyl) benzamide-15N3 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C11H16Cl15N3O5S2, Molecular Weight: 372.83. US Biological Life Sciences. |  Worldwide |
| Rimeporide Hydrochloride | Rimeporide Hydrochloride. Group: Biochemicals. Alternative Names: N- (Aminoiminomethyl) -2-methyl-4, 5-bis (methylsulfonyl) benzamide Hydrochloride. Grades: Highly Purified. CAS No. 187870-95-7. Pack Sizes: 10mg. Molecular Formula: C11H16ClN3O5S2, Molecular Weight: 369.84. US Biological Life Sciences. | Worldwide |
| Rimexolone | Rimexolone is a synthetic glucocorticoid with high receptor affinity, developed specifically for ophthalmic use. Its unique structure a 16α-methyl, 17α-propyl, and 21-nor configuration confers potent anti-inflammatory activity in ocular tissues while promoting rapid systemic metabolism, minimizing systemic glucocorticoid exposure. Applications: Indicated for the treatment of ocular inflammation including postoperative anterior uveitis and conjunctivitis. rimexolone is a glucocorticoid specifically developed for ophthalmic use with a unique 21-nor steroid structure that provides potent local anti-inflammatory activity while promoting rapid systemic metabolism to minimize hpa axis suppression. Category: Active pharmaceutical ingredients. Synonyms: (11b,16a,17b)-11-Hydroxy-16,17-dimethyl-17-(1-oxopropyl)androsta-1,4-dien-3-one. CAS No. 49697-38-3. Product ID: API49697383. Molecular formula: C24H34O3. Mole weight: 370.5. InChIKey: QTTRZHGPGKRAFB-OOKHYKNYSA-N. |  |
| Rimiducid | Rimiducid (AP1903) is a dimerizer agent that acts by cross-linking the FKBP domains. Rimiducid (AP1903) dimerizes the Caspase 9 suicide switch and rapidly induces apoptosis. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AP1903. CAS No. 195514-63-7. Pack Sizes: 1 mg; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16046. |  |
| Rimocidin | It is originally isolated from Str. rimosus and it has antifungal and protozoan effects. Alternative Names: Rimocidine. Grades: >98%. CAS No. 1393-12-0. Molecular formula: C39H61NO14. Mole weight: 767.90. |  |
| Rimonabant | Rimonabant is a selective antagonist of CB1 with IC50 of 13.6 nM and EC50 of 17.3 nM in hCB1 transfected HEK 293 membrane. Alternative Names: SR141716; SR 141716; SR-141716. Grades: >98%. CAS No. 168273-06-1. Molecular formula: C22H21Cl3N4O. Mole weight: 463.79. | |
| Rimonabant | Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with a Ki of 1.8 nM. Rimonabant (SR141716) also inhibits Mycobacterial membrane protein Large 3 (MMPL3). Uses: Scientific research. Category: Signaling pathways. Alternative Names: SR141716. CAS No. 168273-06-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14136. | |
| Rimonabant Hydrochloride | Rimonabant Hydrochloride (SR 141716A Hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an Ki of 1.8 nM. Rimonabant Hydrochloride (SR 141716A Hydrochloride) also inhibits Mycobacterial membrane protein Large 3 (MMPL3). Uses: Scientific research. Category: Signaling pathways. Alternative Names: SR 141716A Hydrochloride. CAS No. 158681-13-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14137. | |
| Rimonabant Hydrochloride | The first of a new class of selective (Cannabinoid-1 (CB-1) receptor antagonists. Group: Biochemicals. Alternative Names: 5-(4-Chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-1-piperidinyl-1H-pyrazole-3-carboxamide hydrochloride. Grades: Highly Purified. CAS No. 158681-13-1. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Rimonabant Hydrochloride | Rimonabant Hydrochloride, used as a tool to investigate CB receptor properties, it is a selective antagonist of cannabinoid CB1 receptor (Ki = 1.98 nM) and inverses adenylyl cyclase inhibition (IC50 = 48 nM). Uses: A brain cannabinoid receptor (cb1) antagonist. antiobesity agent. Alternative Names: 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide; Rimonabant free base, SR141716; SR 141716; SR-141716; A 281; A-281; A281; Rimonabant, Acomplia, Zimulti. Grades: 98%. CAS No. 158681-13-1. Molecular formula: C22H21Cl3N4O.HCl. Mole weight: 500.25. | |
| R-IMPP | R-IMPP (PF-00932239) is an anti-secretagogue of PCSK9 (IC50=4.8 μM), which targets the 80S ribosome to inhibit PCSK9 protein translation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-00932239. CAS No. 2133832-83-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-101354. | |
| Rimsulfuron | Rimsulfuron. Group: Biochemicals. Grades: Highly Purified. CAS No. 122931-48-0. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. US Biological Life Sciences. | Worldwide |
| Rimsulfuron-[d6] | A deuterated labelled Rimsulfuron. Rimsulfuron is used as a pesticide. Alternative Names: N-((4,6-bis(methoxy-d3)pyrimidin-2-yl)carbamoyl)-3-(ethylsulfonyl)pyridine-2-sulfonamide. Grades: > 95%. Molecular formula: C14H11D6N5O7S2. Mole weight: 437.49. | |
| Rimteravimab | Rimteravimab (XVR011) is a bivalent VHH-Fc antibody with potent neutralizing activity with high stability, broad coverage and silenced Fc effector functions against the disease caused by SARS-CoV-2[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: XVR011. CAS No. 2540797-21-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99947. | |
| Rimtuzalcap | Rimtuzalcap (CAD-1883) is a first-in-class selective positive allosteric modulator of small-conductance calcium-activated potassium channels (SK channels). Rimtuzalcap can be used for the research of movement disorders including essential tremor (ET) and spinocerebellar ataxia (SCA)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CAD-1883. CAS No. 2167246-24-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109160. | |
| Rinatabart | HY-P990941 is an FOLR1-targeting IgG1κ type human antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2853518-94-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P990941. | |
| R)-(+)-Indoline-2-carboxylic acid | 5g Pack Size. Group: Building Blocks, Chiral Compounds, Indoles, Organics. Formula: C9H9NO2. CAS No. 98167-06-7. Prepack ID 56971128-5g. Molecular Weight 163.17. See USA prepack pricing. |  |
| R-Indoxacarb | the R-enantiomer of Indoxacarb. Alternative Names: (4aR)-7-Chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]-indeno[1,2-e][1,3,4]oxadiazine-4a(3H)-carboxylic Acid Methyl Ester; (R)-7-Chloro-2,5-dihydro-2-[[(methoxycarbonyl)[4-(trifluoromethoxy)phenyl]amino]carbonyl]-inde. Grades: > 95%. CAS No. 185608-75-7. Molecular formula: C22H17F3N3O7. Mole weight: 527.84. | |
| Rineterkib | Rineterkib is a RAF and ERK1/2 inhibitor developed for the treatment of proliferative diseases characterized by activating mutations in the MAPK pathway. Alternative Names: ERK-IN-1; LTT-462. CAS No. 1715025-32-3. Molecular formula: C26H27BrF3N5O2. Mole weight: 578.4. | |
| Rineterkib | Rineterkib (compound B) is an orally available ERK1 and ERK2 inhibitor in the treatment of a proliferative disease characterized by activating mutations in the MAPK pathway. The activity is particularly related to the treatment of KRAS-mutant NSCLC, BRAF-mutant NSCLC, KRAS-mutant pancreatic cancer, KRAS-mutant colorectal cancer (CRC) and KRAS-mutant ovarian cancer. Rineterkib hydrochloride can also inhibit RAF[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1715025-32-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114491. | |
| Ring expanding impurity of budesonide SM1 | Ring expanding impurity of budesonide SM1. Uses: For analytical and research use. Molecular formula: C23H28O6. Mole weight: 400.47. Catalog: APB06409. |  |
| Ring expanding impurity of budesonide SM2 | Ring expanding impurity of budesonide SM2. Uses: For analytical and research use. Molecular formula: C23H29BrO7. Mole weight: 497.38. Catalog: APB06410. | |
| Ring expanding impurity of budesonide SM4 | Ring expanding impurity of budesonide SM4. Uses: For analytical and research use. Molecular formula: C21H28O6. Mole weight: 376.45. Catalog: APB06411. | |
| RING-type E3 ubiquitin transferase | The RING domain of E3 ubiquitin transferase serves as a mediator bringing the ubiquitin-charged E2 ubiquitin-conjugating enzyme and the acceptor protein together to enable the direct transfer of ubiquitin through the formation of an isopeptide bond between the C-terminal glycine residue of ubiquitin an the ε-amino group of an L-lysine residue of the acceptor protein. The RING-E3 domain does not form a catalytic thioester intermediate with ubiquitin (unlike the HECT domain, EC 2.3.2.26). RING-type ubiquitin transferases may occur as single-chain enzymes but also in dimeric forms or in multi-subunit assemblies. Group: Enzymes. Synonyms: RING E3 ligase (misleading); ubiquitin transferase RING E3. Enzyme Commission Number: EC 2.3.2.27. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2301; RING-type E3 ubiquitin transferase; EC 2.3.2.27; RING E3 ligase (misleading); ubiquitin transferase RING E3. Cat No: EXWM-2301. |  |
| r-N-Nitroso-2-methylpiperidine | r-N-Nitroso-2-methylpiperidine. CAS No. 14026-03-0. Product ID: ACM14026030. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Rink acid Resin | Rink acid Resin. Alternative Names: HO-Methyl-SAL Resin; 4-[(2,4-Dimethoxyphenyl)hydroxymethyl]phenoxy resin; Hydroxymethyl-Super Acid Labile(SAL)-Resin. | |
| Rink amide (aminomethyl)polystyrene (1 % cross-linked) | Rink amide (aminomethyl)polystyrene (1 % cross-linked). |  |
| Rink amide (aminomethyl)polystyrene (extent of labeling: ~1.1mmol/g loading) | Rink amide (aminomethyl)polystyrene (extent of labeling: ~1.1mmol/g loading). | |
| Rink amide AM resin | Rink amide AM resin is an excellent resin for the synthesis of peptide amides using Fmoc strategy. Alternative Names: 4-(2',4'-Dimethoxyphenyl-Fmoc-aminomethyl)phenoxyacetamidoaminomethyl resin. Molecular formula: C39H36N2O6. Mole weight: 628.7. | |
| Rink amide AM resin | Rink amide AM resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| Rink amide-AM Resin | Rink amide resin is used in solid phase peptide synthesis to prepare peptide amides utilizing Fmoc-protected amino acids. Rink Amide-AM resin is similar to Rink Amide-MBHA resin, but it has a narrower range of chemical compatibility. It is also less sensitive to the standard 95% TFA cleavage reaction than Rink Amide resin. | |
| Rink amide AM resin (with Nle) | Rink amide AM resin (with Nle) is an excellent resin for the synthesis of peptide amides using Fmoc strategy. Alternative Names: 4-(2',4'-Dimethoxyphenyl-Fmoc-aminomethyl)phenoxyacetamidonorleucylaminomethyl resin. | |
| Rink amide AM resin (with Nle) | Rink amide AM resin (with Nle). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Rink Amide Linker | Rink amide linker requires concentrated TFA for complete peptide cleavage from the resin. Alternative Names: Fmoc-NH-SAL Resin Linker; Rink Amide Reagent; 4-[(R,S)-α-{1-(9H-Fluoren-9-yl)methoxyformamido}-2,4-dimethoxybenzyl]phenoxyacetic acid. CAS No. 126828-35-1. Molecular formula: C32H29NO7. Mole weight: 539.56. | |
| Rink Amide Linker (4-((2,4-Dimethoxyphenyl)(FMOC amino)methyl)phenoxyacetic acid | 1g Pack Size. Group: Building Blocks, Organics, Peptide Reagents. Formula: C32H29NO7. CAS No. 145069-56-3. Prepack ID 72830185-1g. Molecular Weight 539.58. See USA prepack pricing. | |
| Rink amide MBHA resin, | Rink amide MBHA resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Rink amide MBHA Resin | Rink amide linker requires concentrated TFA for complete peptide cleavage from the resin. This resin is suitable for the synthesis of short peptide amides. Alternative Names: Fmoc-NH-SAL-MBHA Resin; 4-[(2,4-Dimethoxyphenyl)-N-(9-fluorenylmethoxycarbonyl)aminomethyl]phenoxyacetoamido-4-methylbenzhydrylamine resin. Grades: 0.3-0.8mmol/g. CAS No. 431041-83-7. Molecular formula: C47H44N2O6. Mole weight: 732.31993713. | |
| Rink amide MBHA resin (with Norleucine) | Rink amide MBHA resin (with Norleucine). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. | Worldwide |
| Rink amide MBHA resin (with Norleucine) | Resins for solid phase organic synthesis. Alternative Names: Rink amide MBHA resin (with Nle). | |
| Rink amide PEGA Resin | Rink amide linker requires concentrated TFA for complete peptide cleavage from the resin. This resin is suitable for the synthesis of short peptide amides. Alternative Names: 4-[(2,4-Dimethoxyphenyl)-aminomethyl]phenoxyacetamido polyethyleneglycol polyacrylamide copolymer; Rinkamide handled bis-2-acrylamidoprop-1-yl polyethyleneglycol crosslinked dimethyl acrylamide and acryloyl methyl ester. | |
| Rink amide resin | Rink amide resin is an excellent tool for SPPS of peptide amines utilizing Fmoc-protected amino acids. Alternative Names: 4-(2',4'-Dimethoxyphenyl-Fmoc-aminomethyl)phenoxy resin; 2',4'-Di-CH3O-Ph-CH(NH-Fmoc)-Ph-4-OCH2-polystyrene. | |
| Rink amide resin | Rink amide resin. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. | Worldwide |
| Rinucumab | Rinucumab (REGN 2176) is an anti-PDGFR-β antibody. Rinucumab is used for research on neovascular age-related macular degeneration[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: REGN 2176. CAS No. 1569263-06-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99402. | |
| Rinzimetostat | Rinzimetostat (ORIC-944) is a selective, orally active, allosteric inhibitor targeting the EED subunit of polycomb repressive complex 2 (PRC2). Rinzimetostat is synergistic with androgen receptor pathway inhibitors (ARPIs) for the study of metastatic prostate cancer. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ORIC-944. CAS No. 2369769-29-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-158102. | |
| Riociguat | Riociguat is an oral stimulator of soluble guanylate cyclase (sGC) used in the treatment of pulmonary hypertension. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BAY 632521. CAS No. 625115-55-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-14779. | |
| Riociguat | Riocguat is used in the treatment for pulmonary hypertension. Group: Biochemicals. Alternative Names: N-[4,6-Diamino-2-[1-[(2-fluorophenyl)methyl]-1H-pyrazolo[3,4-b]pyridin-3-yl]-5-pyrimidinyl]-N-methylcarbamic Acid Methyl Ester; [4, 6-Diamino-2- [1- [ (2-fluorophenyl) methyl] -1H-pyrazolo [3, 4-b] pyridin-3-yl] -5-pyrimidinyl] methylcarbamic Acid Methyl Ester; BAY 63-2521; BAY 632521; Methyl [4,6-diamino-2-[1-(2-fluorobenzyl)-1H-pyrazolo[3,4-b]pyridin-3-yl]pyrimidin-5-yl]methylcarbamate. Grades: Highly Purified. CAS No. 625115-55-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Riociguat-13C-d6 | Riociguat-13C-d6 is the 13C and deuterated compound of Riociguat. Riociguat has a CAS number of 625115-55-1. Riociguat is a stimulator of guanylate cyclase which causes relaxation of vascular smooth muscle and is used to treat severe pulmonary arterial hypertension. Category: Active pharmaceutical ingredients. CAS No. 1304478-43-0. Product ID: API1304478430. Molecular formula: C20H13D6FN8O2. Mole weight: 428.45. | |
| Riociguat Impurity 10 | Riociguat Impurity 10. Uses: For analytical and research use. CAS No. 256499-19-1. Molecular formula: C14H13ClFN5. Mole weight: 305.74. Catalog: APB256499191. | |
| Riociguat Impurity 11 | Riociguat Impurity 11. Uses: For analytical and research use. CAS No. 1361569-18-7. Molecular formula: C19H15FN8O. Mole weight: 390.38. Catalog: APB1361569187. | |
| Riociguat Impurity 12 | Riociguat Impurity 12. Uses: For analytical and research use. CAS No. 1361569-23-4. Molecular formula: C20H17FN8O. Mole weight: 404.41. Catalog: APB1361569234. | |
| Riociguat Impurity 13 | Riociguat Impurity 13. Uses: For analytical and research use. CAS No. 1361569-10-9. Molecular formula: C18H13FN8O. Mole weight: 376.36. Catalog: APB1361569109. | |
| Riociguat Impurity 14 | Riociguat Impurity 14. Uses: For analytical and research use. CAS No. 625115-54-0. Molecular formula: C22H23FN8O2. Mole weight: 450.48. Catalog: APB625115540. | |
| Riociguat Impurity 15 | Riociguat Impurity 15. Uses: For analytical and research use. Molecular formula: C21H20FN9O3. Mole weight: 465.45. Catalog: APB09587. | |
| Riociguat Impurity 16 | Riociguat Impurity 16. Uses: For analytical and research use. Molecular formula: C18H16FN9O. Mole weight: 393.39. Catalog: APB09588. | |
| Riociguat Impurity 2 | Riociguat Impurity 2. Uses: For analytical and research use. Molecular formula: C20H20N8O2. Mole weight: 404.43. Catalog: APB09584. | |
| Riociguat Impurity 3 | Riociguat Impurity 3. Uses: For analytical and research use. Molecular formula: C20H19FN8O2. Mole weight: 422.42. Catalog: APB09585. | |
| Riociguat Impurity 4 | Riociguat Impurity 4. Uses: For analytical and research use. CAS No. 625115-52-8. Molecular formula: C19H17FN8O2. Mole weight: 408.4. Catalog: APB625115528. | |
| Riociguat Impurity 5 | Riociguat Impurity 5. Uses: For analytical and research use. Molecular formula: C21H21FN8O2. Mole weight: 436.45. Catalog: APB09586. | |
| Riociguat Impurity 6 | Riociguat Impurity 6. Uses: For analytical and research use. CAS No. 2708578-77-0. Molecular formula: C21H19FN8O4. Mole weight: 466.43. Catalog: APB2708578770. | |
| Riociguat Impurity 7 | Riociguat Impurity 7. Uses: For analytical and research use. CAS No. 1702271-98-4. Molecular formula: C18H17FN8. Mole weight: 364.39. Catalog: APB1702271984. | |
| Riociguat Impurity 8 | Riociguat Impurity 8. Uses: For analytical and research use. CAS No. 2518331-19-4. Molecular formula: C22H21FN8O4. Mole weight: 480.46. Catalog: APB2518331194. | |
| Riociguat Impurity 9 | Riociguat Impurity 9. Uses: For analytical and research use. CAS No. 2514697-53-9. Molecular formula: C20H19FN8O2. Mole weight: 422.42. Catalog: APB2514697539. | |
| RIP1/RIP3/MLKL activator 1 | RIP1/RIP3/MLKL activator 1 (Compound 6i) is a potent anti-glioma agent. RIP1/RIP3/MLKL activator 1 induces necroptosis through RIP1/RIP3/MLKL pathway. RIP1/RIP3/MLKL activator 1 exerts acceptable BBB permeability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2682850-41-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144828. | |
| Riparin-2.1 | Riparin-2.1 is an antibacterial peptide isolated from Crinia riparia. It is a narrow-spectrum antibiotic with an MIC of 25 μM against Lactococcus lactis. Alternative Names: Ile-Ile-Glu-Lys-Leu-Val-Asn-Thr-Ala-Leu-Gly-Leu-Leu-Ser-Gly-Leu-NH2. Grades: >96%. Molecular formula: C76H137N19O21. Mole weight: 1653.04. | |
| Ripasudil | Ripasudil (K-115) is a specific inhibitor of ROCK, with IC50s of 19 and 51 nM for ROCK2 and ROCK1, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: K-115. CAS No. 887375-67-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15685. | |
| RIPK1-IN-4 | RIPK1-IN-4 (compound 8) is a potent and selective type II kinase inhibitor of receptor interacting protein 1 (RIP1) kinase and binds to a DLG-out inactive form of RIP1 with an IC50s of 16 nM and 10 nM for RIP1 and ADP-Glo kinase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1481641-08-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18901. | |
| RIPK1-IN-7 | RIPK1-IN-7 is a potent and selective RIPK1 inhibitor with a Kd of 4 nM and an enzymatic IC50 of 11 nM. RIPK1-IN-7 exhibits excellent antimetastasis activity in the experimental B16 melanoma lung metastasis model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2300982-44-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119933. | |
| RIPK3-IN-1 | RIPK3-IN-1 is a RIPK3 type II DFG-out inhibitor with an IC50 of 9.1 nM. RIPK3-IN-1 inhibits RIPK1 and RIPK2 with IC50s of 5.5 and >10 μM. RIPK3-IN-1 is also a c-Met kinase inhibitor with an IC50 of 1.1 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361139-70-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-131064. | |
| RIPK3-IN-3 | RIPK3-IN-3 (compound 20) is a selective inhibitor of RIP kinase RIPK3 (IC50=10 nM). RIPK3 mediates the phosphorylation of Mixed Lineage Kinase (MLKL) and causes necroptosis, while RIPK3-IN-3 inhibits p-MLKL oligomerization and thereby inhibits necroptosis. RIPK3-IN-3 also downregulates CXCL5 secretion and inhibits AsPC-1 cell migration and invasion[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3052303-53-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149393. | |
| Ripple | Ripple. | |
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