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| Product | Description | |
|---|---|---|
| RNA Polymerase II, p14.5 subunit human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. |  |
| RNA Polymerase II, p15.6 subunit, GST tagged human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, p33 subunit, GST tagged human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, p33 subunit human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, RPB10 subunit, GST tagged human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, RPB12 subunit, GST tagged human | recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNA Polymerase II, RPB8 subunit, GST tagged human | recombinant, expressed in E. coli, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| RNase A (10mg/mL, DNase free) | RNase A (10mg/mL, DNase free) is a ribonuclease used to catalyze RNA degradation without containing DNase. RNase A is often employed in cell cycle assay[1][2]. Uses: Scientific research. Group: Signaling pathways. Pack Sizes: 1 mL. Product ID: HY-129046A. |  |
| RNase A, Bovine pancreas | RNase A, Bovine pancreas (Ribonuclease A) cleaves the 3' end of RNA to pyrimidine and actively cleaves RNA at each pyrimidine residue. RNase A, bovine pancreas catalyzes the hydrolysis of single-stranded RNA in the absence of metal ions or cofactors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ribonuclease A; EC 4.6.1.18; RNase A. CAS No. 9001-99-4. Pack Sizes: 25 mg; 50 mg. Product ID: HY-129046. | |
| RNase B, Bovine Pancreas | RNase B, Bovine Pancreas is an N-glycosylated form of bovine pancreatic ribonuclease, which is structurally analogous to RNase A. RNase B, Bovine Pancreas promotes the folding of polypeptide chains and performs a chaperone-like function[1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ribonuclease B, Bovine Pancreas. Pack Sizes: 25 mg; 50 mg; 100 mg. Product ID: HY-129046C. | |
| RNase B Glycoprotein Standard from bovine pancreas | Proteomics Grade. Group: Fluorescence/luminescence spectroscopy. | |
| RNase H | RNase H. Ribonuclease h (rnase h) specifically degrades the rna strand in rna-dna hybrids. it does not hydrolyze the phosphodiester bonds within single-stranded and double-stranded dna and rna. this product is purified from e. coli expressing the recombinant rnha gene on a plasmid with 17 kda molecular weight and it can be inactivated by heating at 65°c for 20 minutes. Group: DNA Modifying Enzymes. Purity: 100U; 5*100KU. Storage: Store at -20°C. Cat No: ME-4003. |  |
| RNA uridylyltransferase | The enzyme requires an oligoribonucleotide or polyribonucleotide with a free terminal 3'-OH as a primer. Group: Enzymes. Synonyms: terminal uridylyltransferase; TUT. Enzyme Commission Number: EC 2.7.7.52. CAS No. 78519-53-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3265; RNA uridylyltransferase; EC 2.7.7.52; 78519-53-6; terminal uridylyltransferase; TUT. Cat No: EXWM-3265. | |
| R)-(+)-N-Benzyl-1-phenylethylamine | R)-(+)-N-Benzyl-1-phenylethylamine. Group: Biochemicals. Alternative Names: (α R) -α -Methyl-N- (phenylmethyl) benzenemethanamine; (+)-Benzylphenethylamine; (+)-N-Benzyl-1-phenylethylamine; (+)-N-Benzyl-α-phenylethylamine; (R)-(+)-N-Benzyl-α-methylbenzylamine; (R)-Benzyl(α-methylbenzyl)amine; (R)-N-(α-Methylbenzyl)-N-benzylamine; (R)-N-Benzyl-1-phenyl-1-ethylamine; (R)-N-Benzyl-1-phenylethanamine; (R)-N-Benzyl-1-phenylethylamine; (R)-N-Benzyl-N-α-methylbenzylamine; (R)-N-Benzyl-α-methylbenzylamine; (R)-N-Benzyl-α-methylbenzylamine; Benzyl((R)-1-phenylethyl)amine; N-Benzyl((R)-1-phenylethyl)amine; N-Benzyl-(R)-α-methylbenzylamine; N- [ (R) -1-Phenylethyl] benzylamine. Grades: Highly Purified. CAS No. 38235-77-7. Pack Sizes: 1g. Molecular Formula: C15H17N, Molecular Weight: 211.3. US Biological Life Sciences. |  Worldwide |
| R-(-)-N-Desmethyl mephenytoin | R-(-)-N-Desmethyl mephenytoin. Group: Biochemicals. Alternative Names: R-(-)-Nirvanol, R-(-)-5-ethyl-5-phenylhydantoin. Grades: Highly Purified. CAS No. 65567-32-01. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C11H12N2O2. US Biological Life Sciences. | Worldwide |
| R-(-)-N-Desmethylmephenytoin (R-(-)-Nirvanol, R-(-)-5-Ethyl-5-phenylhydantoin) | An anticonvulsant, hypnotic. A metabolite of Mephentoin. Group: Biochemicals. Alternative Names: R-(-)-Nirvanol, R-(-)-5-Ethyl-5-phenylhydantoin. Grades: Highly Purified. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| RNF11 human | recombinant, expressed in E. coli (histidine-tagged), ?90% (SDS-PAGE), buffered aqueous solution. Group: Fluorescence/luminescence spectroscopy. | |
| RNF20 active human | recombinant, expressed in baculovirus infected Sf9 cells, ?50% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| r-(+)-N,N'-Dimethyl-7,7'-bis(di(3,5-xylyl)phosphino)-3,3',4,4'-tetrahydro-8,8'-bi-2H-1,4-benzoxazine isopropanol adduct | r-(+)-N,N'-Dimethyl-7,7'-bis(di(3,5-xylyl)phosphino)-3,3',4,4'-tetrahydro-8,8'-bi-2H-1,4-benzoxazine isopropanol adduct. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Xylyl-Solphos SL-A002-2, AGN-PC-00IRC6, 40654_ALDRICH, (R)-7,7 inverted exclamation marka-Bis[bis(3,5-dimethylphenyl)phosphino]-3,3 inverted exclamation marka,4,4 inverted exclamation marka-tetrahydro-4,4 inverted exclamation marka-dimethyl-8,8 inverted exclamation marka-bi(2H-1,4-benzoxazine), (R)-7,7 inverted exclamation marka-Bis[di(3,5-xylyl)phosphino]-3,3 inverted exclamation marka,4,4 invert. Product Category: Heterocyclic Organic Compound. CAS No. 649559-70-6. Molecular formula: C53H62N2O3P2. Mole weight: 837.02. Purity: 0.96. IUPACName: [8-[7-bis(3,5-dimethylphenyl)phosphanyl-4-methyl-2,3-dihydro-1,4-benzoxazin-8-yl]-4-methyl-2,3-dihydro-1,4-benzoxazin-7-yl]-bis(3,5-dimethylphenyl)phosphane. Canonical SMILES: CC1=CC(=CC(=C1)P(C2=C(C3=C(C=C2)N(CCO3)C)C4=C(C=CC5=C4OCCN5C)P(C6=CC(=CC(=C6)C)C)C7=CC(=CC(=C7)C)C)C8=CC(=CC(=C8)C)C)C.CC(C)O. Product ID: ACM649559706. Alfa Chemistry ISO 9001:2015 Certified. |  |
| R-(-)-Norapomorphine hydrochloride | R-(-)-Norapomorphine hydrochloride. Group: Biochemicals. Alternative Names: (6aR)-5,6,6a,7-Tetrahydro-4H-dibenzo[de,g]quinoline-10,11-diol hydrochloride; 6a-b-Noraporphine-10,11-diol hydrochloride; (-)-Norapomorphine hydrochloride. Grades: Highly Purified. CAS No. 420382-69-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C16H16ClNO2. US Biological Life Sciences. | Worldwide |
| RNPA1000 | RNPA1000, an antibiotic , is a potent RnpA inhibitor and inhibits RnpA-mediated cellular RNA degradation. RNPA1000 inhibits tRNA maturation with an IC 50 of 175 μM. RNPA1000 displays broad-spectrum antimicrobial activities and inhibits staphylococcal and all Gram-positive bacterial pathogens activity [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 359600-10-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-12824. | |
| Ro 01-6128 | Ro 01-6128. Group: Biochemicals. Grades: Purified. CAS No. 302841-86-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| RO-0335 | RO-0335 is a novel diphenylether nonnucleoside reverse transcriptase inhibitor. Two pathways to loss of susceptibility to RO-0335 were observed, containing patterns of amino acid changes at either V106I/A plus F227C (with additional contributions from A98G, V108I, E138K, M230L and P236L) or V106I/Y188L (with a potential contribution from L100I, E138K and Y181C). Characterization of the observed mutations by site-directed mutagenesis in the isogenic HXB2D background demonstrated that a minimum of two or more mutations were required for significant loss of susceptibility, with the exception of Y188L, which requires a two-nucleotide change. Patterns containing F227C or quadruple mutations selected by RO-0335 showed a low relative fitness value when compared to wild-type HXB2D. Uses: Designed for use in research and industrial production. Additional or Alternative Names: RO0335; RO-0335; RO 0335. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 867365-76-2. Molecular formula: C21H13BrCl2FN3O4S. Mole weight: 573.22. Purity: >98%. IUPACName: 2-(4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl)-N-(2-chloro-4-sulfamoylphenyl)acetamide. Canonical SMILES: O=C(NC1=CC=C(S(=O)(N)=O)C=C1Cl)CC2=CC=C(Br)C(OC3=CC(C#N)=CC(Cl)=C3)=C2F. Product ID: ACM867365762. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ro 0437626 | Ro 0437626. Group: Biochemicals. Grades: Purified. CAS No. 134362-79-1. Pack Sizes: 1mg, 10mg. US Biological Life Sciences. | Worldwide |
| Ro 04-5595 hydrochloride | Ro 04-5595 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 64047-73-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 04-6790 | Ro 04-6790. Group: Biochemicals. Grades: Purified. CAS No. 202466-68-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 04-6790 dihydrochloride | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro 08-2750 | Ro 08-2750 is a potent and selective Nerve growth factor (NGF) inhibitor that binds the NGF dimer (KD ~ 1 μM). NGF has potential effects on matrix turnover activity and influences the catabolic/anabolic balance of IVD cells in an adverse way that may potentiate IVD degeneration. Anti-NGF treatment might be beneficial to ameliorate progressive tissue breakdown in IVD degeneration and may lead to pain relief. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ro 08-2750; Ro08-2750; Ro-08-2750; Ro 082750; Ro -082750; Ro082750. Product Category: Inhibitors. Appearance: Orange to red solid powder. CAS No. 37854-59-4. Molecular formula: C13H10N4O3. Mole weight: 270.25. Purity: >95%. IUPACName: 2,3,4,10-Tetrahydro-7,10-dimethyl-2,4-dioxobenzo[g]pteridine-8-carboxaldehyde. Canonical SMILES: O=CC1=C(C)C=C2N=C3C(NC(N=C3N(C)C2=C1)=O)=O. Product ID: ACM37854594. Alfa Chemistry ISO 9001:2015 Certified. | |
| Ro 08-2750 | Ro 08-2750 is a non-peptide and reversible nerve growth factor (NGF) inhibitor which binds to NGF, and with an IC50 of ~ 1 ?M. Ro 08-2750 inhibits NGF binding to p75NTR selectively over TRKA[1]. Ro 08-2750 is a selective MSI RNA-binding activity inhibitor, with an IC50 of 2.7 ?M[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 37854-59-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-108466. | |
| Ro 08-2750 | Ro 08-2750. Group: Biochemicals. Grades: Purified. CAS No. 37854-59-4. Pack Sizes: 1mg, 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 09-1679 | Ro 09-1679 is a thrombin inhibitor produced by Mortierella alpina NR6773. It inhibits thrombin, Factor Xa, trypsin and papain with IC50 values of 33.6, 3.3, 0.04 and 0.0346 μmol/L. Synonyms: L-Leucinamide, N2-(3-carboxy-1-oxo-2-propenyl)-L-arginyl-N-(4-((aminoiminomethyl)amino)-1-formylbutyl)-, (S-(E))-. CAS No. 141426-89-3. Molecular formula: C22H39N9O6. Mole weight: 525.61. |  |
| Ro 10-5824 dihydrochloride | Ro 10-5824 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 189744-94-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 106-9920 | Ro 106-9920 is an inhibitor of NF-κB activation, possibly via selective inhibition of LPS- and TNF-α-induced IκBα ubiquitination (IC50 = 3 μM). Ro 106-9920 blocks subsequent production of TNF-α, IL-1 β and IL-6. Inhibits mucin production in an in vitro model of COPD, and is anti-inflammatory following oral administration in vivo. Also weakly inhibits EGFR, 5-lipoxygenase and iNOS. Group: Biochemicals. Alternative Names: 6- (Phenylsulfinyl) tetrazolo[1, 5-b]pyridazine. Grades: Highly Purified. CAS No. 62645-28-7. Pack Sizes: 25mg. US Biological Life Sciences. | Worldwide |
| Ro106-9920 | A cell-permeable tetrazolopyridazine-phenylsulfoxide compound that displays anti-inflammatory properties. Group: Fluorescence/luminescence spectroscopy. | |
| Ro 11-1464 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| RO1138452 | RO1138452 is a potent and selective IP (prostacyclin) receptor antagonist. RO1138452 displays high affinity for IP receptors. In human platelets, pKi is 9.3±0.1; in a recombinant IP receptor system, pKi is 8.7±0.06. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CAY10441. CAS No. 221529-58-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108912. | |
| Ro 1138452 hydrochloride | Ro 1138452 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 15-4513 | Ro 15-4513. Group: Biochemicals. Grades: Purified. CAS No. 91917-65-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 15-4513 | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro15-4513 | Ro15-4513, imidazobenzodiazepinone derivative, is a partial inverse agonist of benzodiazepine receptor (BZR) [1]. Ro15-4513 is a potent ethanol antagonist [2]. Ro15-4513 has anti-anxiety effect [3]. Ro15-4513 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. Uses: Scientific research. Group: Signaling pathways. CAS No. 91917-65-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103476. | |
| Ro 19-4603 | Ro 19-4603. Group: Biochemicals. Grades: Purified. CAS No. 99632-94-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ro 20-1724 | Ro 20-1724. Group: Biochemicals. Grades: Purified. CAS No. 29925-17-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| Ro 20-1724 | Ro 20-1724 (Ro 20-174) is a potent inhibitor of cAMP-specific phosphodiesterase (PDE4/PDE IV) with a Ki of 1930 nM. Neuroprotective effect[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 20-174. CAS No. 29925-17-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100927. | |
| Ro 20-1724 (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) | A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC50=2uM). Inhibits superoxide generation and arachidonic-induced platelet aggregation. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 29925-17-5. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| RO 20-1724, cAMP-specific Phosphodiesterase Inhibitor (4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone) | Cell-permeable. A potent,selective, cAMP-specific phosphodiesterase inhibitor (PDE IV, IC50 = 2 µM). Inhibits superoxide generation and platelet aggregation stimulated by arachidonic acid. Also inhibits fMLP-induced neutrophil adhesion to vascular endothelial cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 29925-17-5. Pack Sizes: 50mg, 250mg. US Biological Life Sciences. | Worldwide |
| Ro-20-1724 - CAS 29925-17-5 | A cell-permeable, selective inhibitor of cAMP-specific phosphodiesterase (PDE IV; IC?? = 2 μM). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 23-9358 | ?97% (HPLC), solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro24-7429 | Ro24-7429 is a potent and orally active HIV-1 transactivator protein Tat antagonist. Ro24-7429 is also a runt-related transcription factor 1 (RUNX1) inhibitor. Ro24-7429 has anti-HIV, antifibrotic and anti-inflammatory effects[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 139339-45-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19149. | |
| Ro 25-6981 | Ro 25-6981 is a potent, selective and activity-dependent NR2B subunit specific NMDA receptor antagonist. Ro 25-6981 shows anticonvulsant and anti-parkinsonian activity. Ro 25-6981 has the potential for the research of parkinson's disease (PD) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 169274-78-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-13993. | |
| Ro 25-6981 hydrochloride hydrate | ?98% (HPLC), powder. Group: Fluorescence/luminescence spectroscopy. | |
| Ro 25-6981 maleate | Potent and selective activity-dependent blocker of NMDA receptors containing the NR2B subunit. IC50 values are 0.009 and 52 μM for cloned receptor subunit combinations NR1C/NR2B and NR1C/NR2A respectively. Displays neuroprotectant effects in vivo and in vitro. Group: Biochemicals. Alternative Names: (αR, βS)-α-(4-Hydroxyphenyl)- β-methyl-4-(phenylmethyl)-1-piperidinepropanol maleate. Grades: Highly Purified. CAS No. 1312991-76-6. Pack Sizes: 1mg, 10mg, 50mg. Molecular Formula: C22H29NO2.C4H4O4, Molecular Weight: 455.55. US Biological Life Sciences. | Worldwide |
| Ro 25-6981 Maleate | Ro 25-6981 Maleate is a potent, selective and activity-dependent NR2B subunit specific NMDA receptor antagonist. Ro 25-6981 Maleat shows anticonvulsant and anti-parkinsonian activity. Ro 25-6981 Maleate has the potential for the research of parkinson's disease (PD) [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1312991-76-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13993A. | |
| Ro 25-6981 maleate salt | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 26-4550 trifluoroacetate | Ro 26-4550 trifluoroacetate. Group: Biochemicals. Grades: Purified. CAS No. 1217448-66-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ro 27-3225 | Ro 27-3225 is a potent and selective melanocortin 4 receptor (MC4R) agonist. CAS No. 274682-89-2. Molecular formula: C39H52N12O6. Mole weight: 784.90. | |
| RO-3 | RO-3 is a potent, CNS-penetrant, and orally active P2X 3 and P2X 2/3 antagonist with pIC 50 s of 5.9 and 7.0 for human homomultimeric P2X 3 and heteromultimeric P2X 2/3 receptors, respectively. RO-3 shows selectivity for P2X 3 and P2X 2/3 over all other functional homomultimeric P2X receptors (IC 50 >10 μM at P2X 1,2,4,5,7 ) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1026582-88-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-19978. | |
| RO-3 | RO-3. Group: Biochemicals. Grades: Purified. CAS No. 1026582-88-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ro 31-0432 | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro-31-7549, Monohydrate - CAS 125313-65-7 | A cell permeable, reversible, selective protein kinase C (PKC) inhibitor (IC?? = 158 nM for rat brain PKC) that acts at the ATP binding site of PKC. Group: Fluorescence/luminescence spectroscopy. | |
| Ro-31-8220 - CAS 138489-18-6 | A cell-permeable, reversible, competitive, and selective inhibitor of protein kinase C (PKC; IC?? = 10 nM) over CaM kinase II (IC?? = 17 μM) and protein kinase A (IC?? = 900 nM). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 31-8220 mesylate | Ro 31-8220 mesylate. Group: Biochemicals. Grades: Purified. CAS No. 138489-18-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Ro 31-8220 mesylate | Ro 31-8220 mesylate is a potent PKC inhibitor, with IC50s of 5, 24, 14, 27, 24 and 23 nM for PKC?, PKC?I, PKC?II, PKC?, PKC? and rat brain PKC, respectively. Ro 31-8220 also significantly inhibits MAPKAP-K1b, MSK1, S6K1 and GSK3? (IC50s, 3, 8, 15, and 38 nM, respectively), with no effect on MKK3, MKK4, MKK6 and MKK7. Ro 31-8220 mesylate can also inhibit the expression of MKP-1, induce the expression of c-Jun, and activate JNK, and these effects possess pharmacological properties independent of PKC[1][2][3][4][5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Ro 31-8220 methanesulfonate; Bisindolylmaleimide IX mesylate. CAS No. 138489-18-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13866. | |
| Ro 31-8220 methanesulfonate salt | solid. Group: Fluorescence/luminescence spectroscopy. | |
| Ro-31-8425 - CAS 131848-97-0 | A potent, cell-permeable, reversible, ATP-competitive, and selective protein kinase C inhibitor (IC?? = 15 nM for rat brain PKC). Group: Fluorescence/luminescence spectroscopy. | |
| RO3201195 | RO3201195 (compound 1) is an inhibitor of p38 MAPK. RO3201195 inhibits WS cell proliferation with IC 50 value of 190 nM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 249937-52-8. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-118612. | |
| Ro-32-0432 - CAS 145333-02-4 | A selective cell-permeable protein kinase C inhibitor. Group: Fluorescence/luminescence spectroscopy. | |
| RO3244794 | RO3244794 is a potent and selective IP (prostacyclin) receptor antagonist, with a pK i of 7.7 and 6.9 in human platelet and recombinant IP receptor system, respectively. RO3244794 exhibits analgesic and anti-inflammatory potential [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 361457-01-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-164580. | |
| Ro3280 | Ro3280 is a Polo-like kinase 1 (PLK1) inhibitor. Ro3280 shows strong antitumor activity in xenograft mouse models, has good selectivity against other kinases and has excellent in vitro cellular potency. Group: Biochemicals. Alternative Names: 4-((9-Cyclopentyl-7,7-difluoro-5-methyl-6-oxo-6,7,8,9-tetrahydro-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino)-3-methoxy-N-(1-methylpiperidin-4-yl)benzamide; 4-[(9-Cyclopentyl-7,7-difluoro-6,7,8,9-tetrahydro-5-methyl-6-oxo-5H-pyrimido[4,5-b][1,4]diazepin-2-yl)amino]-3-methoxy-N-(1-methyl-4-piperidinyl)-benzamide. Grades: Highly Purified. CAS No. 1062243-51-9. Pack Sizes: 5mg. Molecular Formula: C??H??F?N?O?, Molecular Weight: 543.61. US Biological Life Sciences. | Worldwide |
| RO3280 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Ro 3306 | Ro 3306. Group: Biochemicals. Grades: Purified. CAS No. 872573-93-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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