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| Product | Description | |
|---|---|---|
| Toosendanin (Chuanliansu, 12-Acetoxyamoorastatin) | Toosendanin (Chuanliansu, 12-Acetoxyamoorastatin). Group: Biochemicals. Alternative Names: Chuanliansu; 12-Acetoxyamoorastatin. Grades: Plant Grade. CAS No. 58812-37-6. Pack Sizes: 20mg. Molecular Formula: C30H38O11, Molecular Weight: 574.615999999999. US Biological Life Sciences. |  Worldwide |
| TopFluor(R)-PGPE | TopFluor(R)-PGPE. Group: Others. Purity: >99%. Mole weight: 900.834. Stability: 1 Years. Storage: -20°C. 1-Palmitoyl-2-glutaroyl-sn-glycero-3-phosphoethanolamine-N-[4-(dipyrrometheneboron difluoride)butanoyl] (ammonium salt); PGPE. Cat No: PHOZ-018. |  |
| TopFluor(R)-POVPE (DMA) | TopFluor(R)-POVPE (DMA). Group: Others. Purity: >99%. Mole weight: 930.903. Stability: 1 Years. Storage: -20°C. 1-Palmitoyl-2-(5,5-dimethoxyvaleroyl)-sn-glycero-3-phosphoethanolamine-N-[4-(dipyrrometheneboron difluoride)butanoyl] (ammonium salt); POVPE (DMA). Cat No: PHOZ-019. | |
| Topiramate | Topiramate is a kainate GluR5 receptor antagonist, originally used as an anticonvulsant. Synonyms: 2,3:4,5-Bis-O-(1-methylethylidene)-36-D-fructo-pyranose sulfamate. Grade: >98%. CAS No. 97240-79-4. Molecular formula: C12H21NO8S. Mole weight: 339.37. |  |
| Topiramate | Topiramate is a GluR5 kainate receptor antagonist which also inhibits Nav channels, L-type Ca2+ channels, and carbonic anhydrase. CAS No. 97240-79-4. Product ID: API97240794. SMILES: CC1(O[C@@H]2CO[C@@]3([C@H]([C@@H]2O1)OC(O3)(C)C)COS(=O)(=O)N)C. Appearance: Crystalline powder. Category: Active Pharmaceutical Ingredients. |  |
| Topiramate | Topiramate (McN 4853) is a broad-spectrum antiepileptic agent. Topiramate is a GluR5 receptor antagonist. Topiramate produces its antiepileptic effects through enhancement of GABAergic activity, inhibition of kainate/AMPA receptors, inhibition of voltage-sensitive sodium and calcium channels , increases in potassium conductance, and inhibition of carbonic anhydrase [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: McN 4853; RWJ 17021. CAS No. 97240-79-4. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0122. |  |
| Topiramate-[13C6] | An isotope labelled of Topiramate. Topiramate is an anticonvulsant drug. Synonyms: ((3aS,5aR,8aR,8bS)-2,2,7,7-Tetramethyltetrahydro-3aH-bis([1,3]dioxolo)[4,5-b:4',5'-d]pyran-3a-yl-3a,5,5a,8a,8b-13C5)methyl-13C sulfamate. Grade: 98% by CP. CAS No. 1217455-55-4. Molecular formula: C6[13C]6H21NO8S. Mole weight: 345.32. | |
| Topiramate-[d12] | An isotope labelled form of Topiramate. Topiramate is an anticonvulsant drug. It can be used for the treatment of epilepsy. Synonyms: 2,3:4,5-Bis-O-(1-methylethylidene)-β-D-fuctopyranose-d12 1-Sulfamate; Epitoma-d12; Epitomax-d12; McN 4853-d12; RWJ 17021-d12; TPM-d12; Topamac-d12; Topamax-d12; Topimax-d12; Topina-d12; Topomax-d12. Grade: 98% by HPLC; 99% atom D. CAS No. 1279037-95-4. Molecular formula: C12H9D12NO8S. Mole weight: 351.44. | |
| Topiramate-D12 solution | 100 ?g/mL in methanol, ampule of 1 mL, certified reference material. Group: Certified reference materials (crms). |  |
| Topiramate EP Impurity C | Topiramate EP Impurity C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106881-41-8. Molecular formula: C9H17NO8S. Mole weight: 299.29. Catalog: APB106881418. | |
| Topiramate Impurity 12 | Topiramate Impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106881-42-9. Molecular formula: C6H13NO8S. Mole weight: 259.23. Catalog: APB106881429. | |
| Topiramate Impurity 16 | Topiramate Impurity 16. Uses: For analytical and research use. Group: Impurity standards. CAS No. 10489-81-3. Molecular formula: C6H12O6. Mole weight: 180.16. Catalog: APB10489813. | |
| Topiramate Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Topiroxostat | Topiroxostat (FYX-051) is a potent and orally active xanthine oxidoreductase (XOR) inhibitor with an IC 50 value of 5.3 nM and a K i value of 5.7 nM. Topiroxostat exhibits weak CYP3A4 -inhibitory activity (18.6%). Topiroxostat has the potential for hyperuricemia treatment [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: FYX-051. CAS No. 577778-58-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14874. | |
| Topiroxostat | Topiroxostat is a novel and potent xanthine oxidoreductase (XOR) inhibitor. Alternative Names: FYX 051. FYX-051. 4-(5-PYRIDIN-4-YL-1H-1,2,4-TRIAZOL-3-YL)PYRIDINE-2-CARBONITRILE. CAS No. 577778-58-6. Product ID: API577778586. Molecular formula: C13H8N6. Mole weight: 248.24. SMILES: C1=CN=CC=C1C2=NC(=NN2)C3=CC(=NC=C3)C#N. Appearance: Solid. Category: Anti-Gout APIs. | |
| TOPK, active, GST tagged human | recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. | |
| Topo I (197-651) (core domain) human | recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Topo I (C651-765) (C terminal domain) human | recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Topo I (N1-197) (NTD) human | recombinant, expressed in insect cells, ?85% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Topoisomerase I from E. coli, Recombinant | Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA. Enzyme activity is independent of right-and left-handed superhelices. Topoisomerase i (e. coli) catalyzes the relaxation of negatively supercoiled dna. topoisomerase i has also been implicated in knotting and unknotting dna and in linking complementary rings of single-stranded dna into double-stranded rings. the intact holoenzyme is a 97 kda protein. Group: Enzymes. Synonyms: Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. TOPO I. Storage: at -20°C. Form: 50 mM KCl, 10 mM Tris-HCl (pH 7.5), 35 mM (NH4)2SO4, 0.1 mM EDTA, 1 mM DTT and 50% glycerol. Source: E. coli. Species: E. coli. Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. Cat No: NATE-1339. | |
| Topoisomerase I from Human, Recombinant | Topoisomerase I relaxes supercoiled DNA molecules. The enzyme initiates transient breakages and rejoins of phosphodiester bonds in superhelical turns of closed-circular DNA. Enzyme activity is independent of right-and left-handed superhelices. Group: Enzymes. Synonyms: Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. TOPO I. Stability: Stable for 3 months undiluted. Storage: Store at -80°C. It is recommended that the enzyme is aliquoted to avoid repeated freeze-thaw cycles. Source: Baculovirus-infected insect cells (Spodoptera frugiperda). Species: Human. Topoisomerase I; EC 5.99.1.2; type I DNA topoisomerase; untwisting enzyme; relaxing enzyme; nicking-closing enzyme; swivelase; ω-protein; deoxyribonucleate topoisomerase; topoisomerase; type I DNA topoisomerase; DNA topoisomerase; TOPO I. Cat No: NATE-1340. | |
| Topoisomerase II-alpha-b (828-836) | Topoisomerase II-alpha-b (828-836) is a peptide derived from Topoisomerase II-alpha-b. Topoisomerase II-alpha is an enzyme that controls and alters the topologic states of DNA during transcription. Human topoisomerase II enzymes are targets for a number of widely used anticancer agents. | |
| Topoisomerase II inhibitor 14 | Topoisomerase II inhibitor 14 (compound 2f) is a potent inhibtor of Topoisomerase II, with anticancer activity. Topoisomerase II inhibitor 14 induces apoptosis, and arrests cell cycle at S phase. Topoisomerase II inhibitor 14 exhibits antioxidant effect and decreases the level of GSH, MDA, and NO [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 305343-00-4. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-W278582. | |
| Topoisomerase II Inhibitor (BNS-22) | A potent, 2H-chromen-2-one small molecule inhibitor that is selective for TOP2 (IC50=2.8uM and 0.42uM for TOP2a and TOP2b, respectively). Unlike TOP2 poisons such as etoposide, it does not lead to DNA damage associated with DNA Double-Strand Breaks, as evidenced by the lack of y-H2AX accumulation but instead inhibits kinetoplast DNA decatenation in vitro. This compound affects cell cycle at the M phase and disturbs mitotic spindle formation in HeLa cells at 3-10uM. It also exhibits significant anti-proliferative activities against several human cancer cell lines. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Topoisomerase II Inhibitor, BNS-22 | The Topoisomerase II Inhibitor, BNS-22 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. | |
| Topoisomerase II? Inhibitor, TSC24 | The Topoisomerase II? Inhibitor, TSC24 controls the biological activity of Topoisomerase. This small molecule/inhibitor is primarily used for Cell Structure applications. Group: Fluorescence/luminescence spectroscopy. | |
| Topo I (Y723F) (mt Y723F) human | recombinant, expressed in insect cells, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| Topopyrone A | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone A selectively inhibits topoisomerase I with the IC50 of 1.22 ng/mL. It also has anti-Gram-positive bacteria activity. Molecular formula: C18H9ClO7. Mole weight: 372.71. | |
| Topopyrone B | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone B selectively inhibits topoisomerase I with the IC50 of 0.15 ng/mL. It also has anti-Gram-positive bacteria activity and it has a strong inhibitory effect on herpes virus, especially varicella zoster virus (VZV). Molecular formula: C18H9ClO7. Mole weight: 372.71. | |
| Topopyrone C | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone C selectively inhibits topoisomerase I with the IC50 of 4.88 ng/mL. It also has anti-Gram-positive bacteria activity. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Topopyrone D | It is produced by the strain of Phoma sp. BAUA 2861 and Penicillum sp. BAUA 4206. Topopyrone A selectively inhibits topoisomerase I with the IC50 of 19.63 ng/mL. Molecular formula: C18H10O7. Mole weight: 338.27. | |
| Topostatin | Topostatin is originally isolated from Thermomonos pora alba No. 1520. It has inhibitory effects on human tumor cells, and the IC50 of SNB-75 and SNB-78 were 0.4 μmol/L and 7 μmol/L, respectively. Molecular formula: C36H58N4O11S. Mole weight: 754.93. | |
| Topotecan | Topotecan has been used as a positive control for the identification and analysis of HIF-1α and VEGF inhibitors in human glioma cells under hypoxic conditions. It has also been used for in vitro apoptosis assays in PA317 cells. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (4S)-; (4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, (S)-; (S)-Topotecan; 10-Hydroxy-9-[(dimethylamino)methyl]-(20S)-camptothecin; 9-(N,N-Dimethylaminomethyl)-10-hydroxycamptothecin; Evotopin; Hycamptamine; Hycamptin; Nogitecan; NSC 609699; Potactasol; SKF 104864; SKF-S 104864; TopoCED; Topophore C; Topotecan lactone; ZINC 1611274. Grade: ≥95%. CAS No. 123948-87-8. Molecular formula: C23H23N3O5. Mole weight: 421.45. | |
| Topotecan | Topotecan (SKF 104864A; NSC 609669) is an orally active and potent Topoisomerase I inhibitor. Topotecan induces cell cycle arrest in G0/G1 and S phases and promotes apoptosis. Topotecan shows anticancer activity [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SKF 104864A; NSC 609669. CAS No. 123948-87-8. Pack Sizes: 1 mg. Product ID: HY-13768. | |
| Topotecan | Topotecan is a pyranoindolizinoquinoline used as an antineoplastic agent. It is a derivative of camptothecin and works by binding to the topoisomerase I-DNA complex and preventing religation of these 328 single strand breaks. It has a role as an EC 5.99.1.2 (DNA topoisomerase) inhibitor and an antineoplastic agent. Alternative Names: Topotecan lactone. Hycamptamine. Hycamptin. CAS No. 123948-87-8. Product ID: API123948878. Molecular formula: C23H23N3O5. Mole weight: 421.4. EINECS: 687-471-1. SMILES: CCC1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O. Appearance: Light Yellow to Yellow Solid. Category: Anti-Tumor APIs. | |
| Topotecan carboxylic acid sodium salt | Topotecan carboxylic acid sodium salt. Group: Biochemicals. Alternative Names: 1-[ (Dimethylamino)methyl]-a-ethyl-9, 11-dihydro-a, 2-dihydroxy-8- (hydroxymethyl)-9-oxo-indolizino[1, 2-b]quinoline-7-acetic acid. Grades: Highly Purified. CAS No. 123949-08-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C23H24N3NaO6. US Biological Life Sciences. | Worldwide |
| Topotecan-d5 | Labeled Topotecan. A DNA topoisomerase I inhibitor; semisynthetic analog of Camptothecin. Antineoplastic. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-4- (ethyl-d5)-4, 9-dihydroxy-1H-pyrano[3, 4, 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione; NSC-609669-d5; SKF-104864A-d5; Hycamtin-d5. Grades: Highly Purified. CAS No. 1133355-98-2. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Topotecan-[d5] | Topotecan-[d5] is the labelled analogue of Topotecan. Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Uses: Labelled topotecan (t542500). a dna topoisomerase i inhibitor; semisynthetic analog of camptothecin. antineoplastic. Synonyms: Topotecan D5. Grade: 95% atom D. CAS No. 1133355-98-2. Molecular formula: C23H18D5N3O5. Mole weight: 426.48. | |
| Topotecan-d6 | Topotecan-d6 is the deuterium labeled Topotecan. Topotecan (SKF 104864A; NSC 609669) is a Topoisomerase I inhibitor. The IC50 values of Topotecan at 24 h are 2.73±0.25 μM of U251 cells, 2.95±0.23 μM of U87 cells, 5.46±0.41 μM of GSCs-U251 and 5.95 μM of GSCs-U87. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4',6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC-609669-d6; SKF-104864A-d6; Hycamtin-d6. Product Category: Inhibitors. Appearance: Yellow Solid. CAS No. 1044904-10-0. Molecular formula: C23H17D6N3O5. Mole weight: 427.48. Purity: 0.96. IUPACName: Topotecan-d6. Canonical SMILES: CCC1(C2=C(COC1=O)C(=O)N3CC4=C(C3=C2)N=C5C=CC(=C(C5=C4)CN(C)C)O)O. Product ID: ACM1044904100. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Topotecan-d6 | Labelled Topotecan, a DNA topoisomerase inhibitor. Group: Biochemicals. Grades: Highly Purified. CAS No. 1044904-10-0. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Topotecan-[d6] | One isotopic labelled form of Topotecan, which is a topoisomerase I inhibitor and has been found to be an effective antineoplastic agent. Synonyms: (4S)-10-[(Dimethylamino-d6)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4',6-7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; NSC-609669-d6; SKF-104864A-d6; Hycamtin-d6. Grade: 95% by HPLC; 98% atom D. CAS No. 1044904-10-0. Molecular formula: C23H17D6N3O5. Mole weight: 427.48. | |
| Topotecan HCl | Topotecan HCl. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-4-ethyl-4, 9-dihydroxy-1H-pyrano[3', 4', 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione hydrochloride; NSC-609669; SKF-104864A. Grades: Highly Purified. CAS No. 119413-54-6. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C23H24ClN3O5. US Biological Life Sciences. | Worldwide |
| Topotecan hydrochloride | Topocecan is a semisynthetic derivative of camptothecin with antineoplastic activity. During the S phase of the cell cycle, topotecan selectively stabilizes topoisomerase I-DNA covalent complexes, inhibiting religation of topoisomerase I-mediated single-strand DNA breaks and producing potentially lethal double-strand DNA breaks when complexes are encountered by the DNA replication machinery. Camptothecin is a cytotoxic quinoline-based alkaloid extracted from the Asian tree Camptotheca acuminata. Uses: Topoisomerase i inhibitors. Synonyms: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, hydrochloride (1:1), (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (4S)-; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-; (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride; Hycamtin; Nogitecan hydrochloride; NSC 609669; SKF 104864A; SKFS 104864A; Topotecan chlorohydrate; Xinze. Grade: >98%. CAS No. 119413-54-6. Molecular formula: C23H24ClN3O5. Mole weight: 457.91. | |
| Topotecan hydrochloride | Topotecan hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 119413-54-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Topotecan hydrochloride | Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 1,4-Di[4-(3-phenoxypropoxy)-2-butynyl]piperazine. Product Category: Inhibitors. Appearance: Light-yellow powder. CAS No. 119413-54-6. Molecular formula: C23H24ClN3O5. Mole weight: 457.91. Purity: 0.98. IUPACName: (19S)-8-[(dimethylamino)methyl]-19-ethyl-7,19-dihydroxy-17-oxa-3,13-diazapentacyclo[11.8.0.02,11.04,9.015,20]henicosa-1(21),2,4(9),5,7,10,15(20)-heptaene-14,18-dione;hydrochloride. Canonical SMILES: CC[C@@]1(C2=C(COC1=O)C(=O)N3CC4=CC5=C(C=CC(=C5CN(C)C)O)N=C4C3=C2)O.Cl. Product ID: ACM119413546. Alfa Chemistry ISO 9001:2015 Certified. | |
| Topotecan hydrochloride | Topotecan Hydrochloride (SKF 104864A Hydrochloride) is a Topoisomerase I inhibitor with potent antineoplastic activities. Uses: Scientific research. Group: Natural products. Alternative Names: SKF 104864A hydrochloride; NSC 609669 hydrochloride. CAS No. 119413-54-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13768A. | |
| Topotecan Hydrochloride | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardschiral moleculesenzyme activators, inhibitors & substrates. Alternative Names: 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (S)-, Hycamtin, SKF-S-104864-A, (S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[l,2-b]quinoline-3,14(4H,12H)-dione monohydrochloride, 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 10-[(dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-, monohydrochloride, (4S)- (9CI), Nogitecan hydrochloride, Topotecan hydrochloride, SKFS 104864A, Xinze, SKF-S-104864,(4S)-10-[(Dimethylamino)methyl]-4-ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione Hydrochloride (1:1), SKF 104864A, Topotecan chlorohydrate, SKF-S-106567, NSC 609669. | |
| Topotecan, Hydrochloride ( (4S)-10-[ (Dimethylamino)methyl]-4-ethyl-4, 9-dihydroxy-1H-pyrano[3, 4, 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione, Hydrochloride, SKF-104864A,) | A DNA topoisomerase inhibitor. Group: Biochemicals. Alternative Names: (4S)-10-[ (Dimethylamino)methyl]-4-ethyl-4, 9-dihydroxy-1H-pyrano[3, 4, 6-7]indolizino[1, 2-b]quinoline-3, 14 (4H, 12H)-dione, Hydrochloride, SKF-104864A. Grades: Highly Purified. CAS No. 119413-54-6. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Topotecan hydrochloride hydrate | ?98% (HPLC and enzymatic). Group: Fluorescence/luminescence spectroscopy. | |
| Topotecan Hydrochloride Liposome (PEGylated) | Topotecan Hydrochloride (TPT) is a semi-synthetic derivative of the plant alkaloid camptothecin (CPT) with cytotoxic properties. Like other drugs in the CPT family, TPT is a specific inhibitor of topoisomerase I, causing lethal DNA damage in the S phase of mitosis. Liposome preparation and anti-tumor activity research. This product is a pre-formulated liposome encapsulating Topotecan Hydrochloride. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| Topotecan Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Topotecan Related Compound C | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Topramezone | analytical standard. Group: Pesticides & metabolites standardspesticides & metabolitespesticides & metabolites. | |
| TO-PRO-3 iodide | TO-PRO-3 iodide is a highly efficient blue fluorescent dye that can stain cytoplasm as a cell tracer. Uses: Scientific research. Group: Fluorescent dye. CAS No. 157199-63-8. Pack Sizes: 671 μg (5 mM * 200 μL in DMSO). Product ID: HY-117070. | |
| TOPS | TOPS is a highly water-soluble aniline derivative widely used in diagnostics and biological experiments. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 40567-80-4. Pack Sizes: 10 mM * 1 mL; 500 mg; 1 g; 5 g. Product ID: HY-15933. | |
| Torachrysone | Torachrysone is a natural phenol isolated from the seeds of Cassia obtusifolia. Synonyms: 2-Acetyl-3-methyl-6-methoxynaphthalene-1,8-diol. Grade: >97%. CAS No. 22649-04-3. Molecular formula: C14H14O4. Mole weight: 246.3. | |
| Torachrysone | Torachrysone. Group: Biochemicals. Grades: Highly Purified. CAS No. 22649-04-3. Pack Sizes: 25mg, 50mg. US Biological Life Sciences. | Worldwide |
| Torachrysone 8-O-glucoside | Torachrysone 8-O-glucoside is a natural compound found in the rhizoma of Rheum officinale L. For its inhibitory activities of alpha-glucosidase, it may be used for the treatment of type 2 diabetes. Uses: Anti-diabetes. Synonyms: 7-Acetyl-8-hydroxy-3-methoxy-6-methyl-1-naphthyl β-D-glucopyranos ide. Grade: >98%. CAS No. 64032-49-1. Molecular formula: C20H24O9. Mole weight: 408.40. | |
| Torasemide | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C16H20N4O3S. CAS No. 56211-40-6. Prepack ID 86431125-1g. Molecular Weight 348.42. See USA prepack pricing. |  |
| Torasemi impurity 11 | Torasemi impurity 11. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106944-62-1. Molecular formula: C16H20N4O3S. Mole weight: 348.42. Catalog: APB106944621. | |
| Torasemi impurity 12 | Torasemi impurity 12. Uses: For analytical and research use. Group: Impurity standards. CAS No. 106944-63-2. Molecular formula: C16H20N4O3S. Mole weight: 348.42. Catalog: APB106944632. | |
| Torcetrapib | Torcetrapib (CP-529414) is a selective, potent cholesteryl ester transfer protein ( CETP ) inhibitor. A typical inhibition curve for whole human plasma, having a CETP concentration of 37 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP-529414. CAS No. 262352-17-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-12089. | |
| Torcetrapib | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Torcetrapib | Cholesteryl ester transfer protein (CETP) inhibitor. Antilipemic; antiatherosclerotic. Group: Biochemicals. Alternative Names: (2R, 4S) -4-[[[3, 5-Bis (trifluoromethyl) phenyl]methyl] (methoxycarbonyl) amino]-2-ethyl-3, 4-dihydro-6- (trifluoromethyl) -. Grades: Highly Purified. CAS No. 262352-17-0. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Toreforant | Toreforant is a potent and selective histamine H 4 receptor ( H4R ) antagonist, with a K i at the human receptor of 8.4 nM. Uses: Scientific research. Group: Signaling pathways. Alternative Names: JNJ-38518168. CAS No. 952494-46-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16756. | |
| Toremifene | Toremifene (Z-Toremifene) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC 50 of 0.07 μM and 2.6 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Toremifene; NK 622 free base; FC-1157a free base. CAS No. 89778-26-7. Pack Sizes: 10 mM * 1 mL; 10 mg; 25 mg. Product ID: HY-B0005A. | |
| Toremifene citrate | Toremifene citrate. Group: Biochemicals. Alternative Names: 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine 2-hydroxy-1,2,3-propanetricarboxylate. Grades: Highly Purified. CAS No. 89778-27-8. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C32H36ClNO8. US Biological Life Sciences. | Worldwide |
| Toremifene citrate | Toremifene citrate (Z-Toremifene citrate) is a second-generation selective estrogen-receptor modulator (SERM) in development for the prevention of osteoporosis. Toremifene citrate also potent inhibits infectious EBOV Zaire and Marburg (MARV) with IC 50 of 0.07 μM and 2.6 μM, respectively [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Z-Toremifene citrate; NK 622; FC-1157a. CAS No. 89778-27-8. Pack Sizes: 10 mM * 1 mL; 100 mg; 500 mg. Product ID: HY-B0005. | |
| Toremifene citrate | 100mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C32H36ClNO8. CAS No. 89778-27-8. Prepack ID 10914059-100mg. Molecular Weight 598.08. See USA prepack pricing. | |
| Toremifene Citrate (2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine) | An antiestrogen and antineoplastic. Nonsteroidal antiestrogen structurally similar to tamoxifen. Group: Biochemicals. Alternative Names: 2-[4-[(1Z)-4-Chloro-1,2-diphenyl-1-butenyl]phenoxy]-N,N-dimethylethanamine. Grades: Highly Purified. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
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