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Bortezomib Impurity 40. Uses: For analytical and research use. Alternative Names: (S)-3-methyl-1-((3aR,4R,6R,7aS)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butan-1-amine. Molecular formula: C15H28BNO2. Mole weight: 265.20. Catalog: APB03317.
Bortezomib Impurity 41
Bortezomib Impurity 41. Uses: For analytical and research use. Alternative Names: tert-butyl ((S)-1-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)carbamate. Molecular formula: C29H45BN2O5. Mole weight: 512.49. Catalog: APB03513.
Bortezomib Impurity 42
Bortezomib Impurity 42. Uses: For analytical and research use. Alternative Names: (S,Z)-N-(1-((3-methylbut-1-en-1-yl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. CAS No. 2276538-67-9. Molecular formula: C19H22N4O2. Mole weight: 338.40. Catalog: APB2276538679.
Bortezomib Impurity 43
Bortezomib Impurity 43. Uses: For analytical and research use. CAS No. 205393-21-1. Molecular formula: C24H38BClN2O3. Mole weight: 448.84. Catalog: APB205393211.
Bortezomib Impurity 43
Bortezomib Impurity 43. Uses: For analytical and research use. Alternative Names: ((R)-3-methyl-1-((R)-3-phenyl-2-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic acid. Molecular formula: C28H34BN5O5. Mole weight: 531.41. Catalog: APB03512.
Bortezomib Impurity 44
Bortezomib Impurity 44. Uses: For analytical and research use. Alternative Names: (3aS,4S,6S,7aR)-2-((S)-1-chloro-3-methylbutyl)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborole. CAS No. 85167-14-2. Molecular formula: C15H26BClO2. Mole weight: 284.17. Catalog: APB85167142.
Bortezomib Impurity 45
Bortezomib Impurity 45. Uses: For analytical and research use. Molecular formula: C40H50N6O7. Mole weight: 726.88. Catalog: APB06370.
Bortezomib Impurity 45
Bortezomib Impurity 45. Uses: For analytical and research use. Alternative Names: 1,1,1-trimethyl-N-((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)-N-(trimethylsilyl)silanamine. CAS No. 514820-48-5. Molecular formula: C21H44BNO2Si2. Mole weight: 409.30. Catalog: APB514820485.
Bortezomib Impurity 46
Bortezomib Impurity 46. Uses: For analytical and research use. CAS No. 948294-96-0. Molecular formula: C14H23BN2O3. Mole weight: 278.16. Catalog: APB948294960.
Bortezomib Impurity 46
Bortezomib Impurity 46. Uses: For analytical and research use. Alternative Names: N-((R)-1-(((S)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Molecular formula: C29H39BN4O4. Mole weight: 518.31. Catalog: APB03511.
Bortezomib Impurity 47
Bortezomib Impurity 47. Uses: For analytical and research use. Alternative Names: N-((S)-1-(((S)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Molecular formula: C29H39BN4O4. Mole weight: 518.31. Catalog: APB03510.
Bortezomib Impurity 48
Bortezomib Impurity 48. Uses: For analytical and research use. Alternative Names: (R)-3-phenyl-2-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanoic acid. Molecular formula: C23H22N4O4. Mole weight: 418.16. Catalog: APB03509.
Bortezomib Impurity 49
Bortezomib Impurity 49. Uses: For analytical and research use. Alternative Names: (S)-3-phenyl-2-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanoic acid. CAS No. 1194235-14-7. Molecular formula: C23H22N4O4. Mole weight: 418.16. Catalog: APB1194235147.
Bortezomib Impurity 49
Bortezomib Impurity 49. Uses: For analytical and research use. CAS No. 4664-57-7. Molecular formula: C11H16O3S. Mole weight: 228.31. Catalog: APB4664577.
Bortezomib Impurity 50
Bortezomib Impurity 50. Uses: For analytical and research use. Alternative Names: (S)-3-phenyl-2-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanoic acid. Molecular formula: C23H22N4O4. Mole weight: 418.16. Catalog: APB03508.
Bortezomib Impurity 51
Bortezomib Impurity 51. Uses: For analytical and research use. Alternative Names: (R)-3-phenyl-2-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanoic acid. Molecular formula: C23H22N4O4. Mole weight: 418.16. Catalog: APB03507.
Bortezomib Impurity 51
Bortezomib Impurity 51. Uses: For analytical and research use. CAS No. 2415205-36-4. Molecular formula: C17H29BF3NO4. Mole weight: 379.23. Catalog: APB2415205364.
Bortezomib Impurity 52
Bortezomib Impurity 52. Uses: For analytical and research use. Alternative Names: (S)-2-((S)-2-amino-3-phenylpropanamido)-3-phenylpropanoic acid. CAS No. 2577-40-4. Molecular formula: C18H20N2O3. Mole weight: 312.15. Catalog: APB2577404.
Bortezomib Impurity 52
Bortezomib Impurity 52. Uses: For analytical and research use. CAS No. 94242-85-0. Molecular formula: C7H15BO2. Mole weight: 142.01. Catalog: APB94242850.
Bortezomib Impurity 53
Bortezomib Impurity 53. Uses: For analytical and research use. CAS No. 389799-97-7. Molecular formula: C5H14BNO2. Mole weight: 130.98. Catalog: APB389799977.
Bortezomib Impurity 53
Bortezomib Impurity 53. Uses: For analytical and research use. Alternative Names: (R)-2-((S)-2-amino-3-phenylpropanamido)-3-phenylpropanoic acid. CAS No. 2577-12-0. Molecular formula: C18H20N2O3. Mole weight: 312.15. Catalog: APB2577120.
Bortezomib Impurity 54
Bortezomib Impurity 54. Uses: For analytical and research use. Alternative Names: (R)-2-((R)-2-amino-3-phenylpropanamido)-3-phenylpropanoic acid. CAS No. 58607-69-5. Molecular formula: C18H20N2O3. Mole weight: 312.15. Catalog: APB58607695.
Bortezomib Impurity 54 (Trifluoroacetate)
Bortezomib Impurity 54 (Trifluoroacetate). Uses: For analytical and research use. Alternative Names: 58607-69-5(free base); (R)-2-((R)-2-amino-3-phenylpropanamido)-3-phenylpropanoic acid compound with 2,2,2-trifluoroacetic acid. Molecular formula: C18H20N2O3·CF3COOH. Mole weight: 426.14. Catalog: APB03506.
Bortezomib Impurity 55
Bortezomib Impurity 55. Uses: For analytical and research use. Alternative Names: (S)-2-((R)-2-amino-3-phenylpropanamido)-3-phenylpropanoic acid. CAS No. 2577-22-2. Molecular formula: C18H20N2O3. Mole weight: 312.15. Catalog: APB2577222.
Bortezomib Impurity 7
Bortezomib Impurity 7. Uses: For analytical and research use. Molecular formula: C19H25BN4O5. Mole weight: 400.24. Catalog: APB06402.
Bortezomib Impurity 7
An impurity of Bortezomib. Bortezomib is a proteasome inhibitor primarily used in the treatment of multiple myeloma (MM) and mantle cell lymphoma (MCL). Synonyms: (R)-(3-Methyl-1-(pyrazine-2-carboxamido)butyl)boronic acid; Bortezomib Related Compound A. Grade: ≥95%. Molecular formula: C10H16BN3O3. Mole weight: 237.07.
Bortezomib Impurity 8
Bortezomib Impurity 8. Uses: For analytical and research use. Molecular formula: C24H27BN6O5. Mole weight: 490.33. Catalog: APB06368.
Bortezomib Impurity 9
Bortezomib Impurity 9 is an impurity of Bortezomib and a tripeptide boronic acid proteasome inhibitor used as an antitumor agent. Synonyms: N-(2-Pyrazinylcarbonyl)-L-phenylalanyl-N-[(1R)-1-borono-3-methylbutyl]-L-phenylalaninamide ; ((R)-3-Methyl-1-((S)-3-phenyl-2-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic Acid. Grade: > 95%. CAS No. 1194235-41-0. Molecular formula: C28H34BN5O5. Mole weight: 531.42.
Bortezomib Impurity A
Bortezomib Impurity A. Uses: For analytical and research use. Alternative Names: (R)-(3-methyl-1-(pyrazine-2-carboxamido)butyl)boronic acid. Molecular formula: C10H16BN3O3. Mole weight: 237.06. Catalog: APB03418.
Bortezomib Impurity B
Bortezomib Impurity B. Uses: For analytical and research use. Alternative Names: (S)-N-(1-amino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. CAS No. 289472-80-6. Molecular formula: C14H14N4O2. Mole weight: 270.29. Catalog: APB289472806.
Bortezomib Impurity B
Bortezomib Impurity B is used for the synthesis of Bortezomib. Synonyms: N-(2-pyrazinylcarbonyl)-L-phenylalanine; 3-Phenyl-2-[(pyrazine-2-carbonyl)amino]propionic Acid; (S)-3-Phenyl-2-(pyrazine-2-carbonylamino)propanoic Acid. Grade: 98% by HNMR. CAS No. 114457-94-2. Molecular formula: C14H13N3O3. Mole weight: 271.28.
Bortezomib Impurity C
Bortezomib Impurity C. Uses: For analytical and research use. Alternative Names: ((R)-3-hydroxy-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. Molecular formula: C19H25BN4O5. Mole weight: 400.24. Catalog: APB03420.
Bortezomib Impurity D
Bortezomib Impurity D. Uses: For analytical and research use. Alternative Names: (S)-3-phenyl-2-(pyrazine-2-carboxamido)propanoic acid. CAS No. 114457-94-2. Molecular formula: C14H13N3O3. Mole weight: 271.27. Catalog: APB114457942.
Bortezomib Impurity E
Bortezomib Impurity E. Uses: For analytical and research use. Alternative Names: (S)-N-(1-formamido-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Molecular formula: C15H14N4O3. Mole weight: 298.3. Catalog: APB03419.
Bortezomib Impurity F
Bortezomib Impurity F. Uses: For analytical and research use. Alternative Names: (S)-N-(1-(3-hydroxy-3-methylbutanamido)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. CAS No. 2379402-85-2. Molecular formula: C19H22N4O4. Mole weight: 370.4. Catalog: APB2379402852.
Bortezomib Impurity F
Bortezomib Impurity F is used for the synthesis of Bortezomib. Synonyms: 3-Phenyl-2-[(pyrazine-2-carbonyl)-amino]-propionic Acid Methyl Ester; N-Pyrazinylcarbonyl-L-phenylalanine Methyl Ester; N-(2-Pyrazinylcarbonyl)-L-phenylalanine Methyl Ester. Grade: > 95%. CAS No. 73058-37-4. Molecular formula: C15H15N3O3. Mole weight: 285.31.
Bortezomib Impurity G
Bortezomib Impurity G is an impurity of the acclaimed drug Bortezomib, a drug tailored towards the affliction of multiple myeloma. Synonyms: (S)-Hydroxy Des(boric Acid) Bortezomib; N-[(1S)-2-[[(1S)-1-hydroxy-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-2-Pyrazinecarboxamide. Grade: > 95%. CAS No. 289472-81-7. Molecular formula: C19H24N4O3. Mole weight: 356.43.
Bortezomib Impurity G
Bortezomib Impurity G. Uses: For analytical and research use. Alternative Names: ((S)-3-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. CAS No. 1132709-14-8. Molecular formula: C19H25BN4O4. Mole weight: 384.24. Catalog: APB1132709148.
Bortezomib Impurity H
Bortezomib Impurity H. Uses: For analytical and research use. Alternative Names: ((R)-3-methyl-1-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. CAS No. 1132709-15-9. Molecular formula: C19H25BN4O4. Mole weight: 384.24. Catalog: APB1132709159.
Bortezomib Impurity H
Bortezomib Impurity H is an impurity of Bortezomib, a therapeutic agent for treating multiple myeloma and mantle cell lymphoma. Synonyms: (S)-N-(1-(isopentylaMino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxaMide. Grade: > 95%. CAS No. 1446194-56-4. Molecular formula: C19H24N4O2. Mole weight: 340.43.
Bortezomib Impurity I
Bortezomib Impurity I. Uses: For analytical and research use. Alternative Names: N-((S)-1-(((R)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. CAS No. 289472-78-2. Molecular formula: C19H24N4O3. Mole weight: 356.42. Catalog: APB289472782.
Bortezomib Impurity J
Bortezomib Impurity J. Uses: For analytical and research use. Alternative Names: N-((S)-1-(((S)-1-hydroxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. CAS No. 289472-81-7. Molecular formula: C19H24N4O3. Mole weight: 356.42. Catalog: APB289472817.
Bortezomib Impurity L
Bortezomib Impurity L. Uses: For analytical and research use. Alternative Names: N-((S)-1-(((R)-1-hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. CAS No. 886979-78-8. Molecular formula: C19H24N4O4. Mole weight: 372.42. Catalog: APB886979788.
Bortezomib Impurity M
Bortezomib Impurity M. Uses: For analytical and research use. Alternative Names: N-((S)-1-(((S)-1-hydroperoxy-3-methylbutyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. CAS No. 886979-81-3. Molecular formula: C19H24N4O4. Mole weight: 372.42. Catalog: APB886979813.
Bortezomib Impurity O
Bortezomib Impurity O. Uses: For analytical and research use. Alternative Names: ((R)-3-methyl-1-((S)-3-phenyl-2-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic acid. CAS No. 1194235-41-0. Molecular formula: C28H34BN5O5. Mole weight: 531.41. Catalog: APB1194235410.
Bortezomib Impurity P
Bortezomib Impurity P. Uses: For analytical and research use. Alternative Names: ((R)-3-methyl-1-((S)-3-phenyl-2-((R)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propanamido)butyl)boronic acid. Molecular formula: C28H34BN5O5. Mole weight: 531.41. Catalog: APB03417.
Bortezomib Impurity (R,R-Isomer)
Bortezomib Impurity (R,R-Isomer) is a diastereomer of Bortezomib. Synonyms: (1R,2R)-Bortezomib; B-[(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; [(1R)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid. Grade: 98% by HPLC. CAS No. 1132709-15-9. Molecular formula: C19H25BN4O4. Mole weight: 384.25.
Bortezomib Impurity (R,S-Isomer)
Bortezomib Impurity (R,S-Isomer) is a diastereomer of Bortezomib. Synonyms: (1S,2R)-Bortezomib; B-[(1S)-3-Methyl-1-[[(2R)-1-oxo-3-phenyl-2-[(2-pyrazinylcarbonyl)amino]propyl]amino]butyl]boronic Acid; N-(2-Pyrazinecarbonyl)-D-phenylalanine-D-leucine boronic anhydride. Grade: > 95%. CAS No. 1132709-16-0. Molecular formula: C19H25BN4O4. Mole weight: 384.25.
Bortezomib Impurity V
Bortezomib Impurity V. Uses: For analytical and research use. CAS No. 292061-26-8. Molecular formula: C14H23ClN2O. Mole weight: 270.8. Catalog: APB292061268.
Bortezomib Impurity WQ
Bortezomib Impurity WQ. Uses: For analytical and research use. Alternative Names: 3-methylbutanal. Molecular formula: C5H10O. Mole weight: 86.13. Catalog: APB03416.
Bortezomib Impurity Z
Bortezomib Impurity Z. Uses: For analytical and research use. Alternative Names: ((R)-2-methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)propyl)boronic acid. Molecular formula: C18H23BN4O4. Mole weight: 370.21. Catalog: APB03414.
Bortezomib Liposome (PEGylated)
Bortezomib (BTZ) is a proteasome inhibitor used to treat various malignancies, including lung cancer, prostate cancer, colorectal cancer, breast cancer, etc. This product is a pre-formulated liposome encapsulating Bortezomib. It is only for research purposes. Group: Drug-loaded liposome.
Bortezomib Pinanediol Ester
Bortezomib-pinanediol is a prodrug of Bortezomib and a proteasome inhibitor. Synonyms: N-((S)-1-(((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)amino)-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide; (1R)-(1S,2S,3R,5S)-Pinanediol-N-(N-pyrazinylphenylalaninoyl)-1-amino-3-methyl-butane-1-boronate; Bortezomib Pinanediol Impurity. Grade: 97+%. CAS No. 205393-22-2. Molecular formula: C29H39BN4O4. Mole weight: 518.46.
Bortezomib (Standard)
Bortezomib (Standard) is the analytical standard of Bortezomib. This product is intended for research and analytical applications. Bortezomib (PS-341) is a reversible and selective proteasome inhibitor, and potently inhibits 20S proteasome (Ki=0.6 nM) by targeting a threonine residue. Bortezomib disrupts the cell cycle, induces apoptosis, and inhibits NF-κB. Bortezomib is the first proteasome inhibitor anticancer agent. Bortezomib can be used for the study of multiple myeloma (MM)[1][2]. Bortezomib effectively inhibits TREM2 expression in tumor-associated macrophages (TAMs)[7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PS-341 (Standard); LDP-341 (Standard); NSC 681239 (Standard). CAS No. 179324-69-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10227R.
Bortezomib USP Impurity G
Bortezomib USP Impurity G is an isomer of Bortezomib. It has been demonstrated to inhibit serine proteases shown to lower cellular Aβ concentrations, associated with Alzheimer's or hypertension. Synonyms: (1S,2S)-Bortezomib; ((S)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid. Grade: 95%. CAS No. 1132709-14-8. Molecular formula: C19H25BN4O4. Mole weight: 384.243.
Bortezomib USP Related Compoud B
Bortezomib USP Related Compoud B is an impurity of the acclaimed drug Bortezomib, which is a drug tailored towards the affliction of multiple myeloma. Synonyms: Bortezomib Amide Impurity; N-[(1S)-2-Amino-2-oxo-1-(phenylmethyl)ethyl]-2-pyrazinecarboxamide; N-[(1S)-2-amino-2-oxo-1-(phenylmethyl)ethyl]pyrazinecarboxamide; (S)-N-(1-AMino-1-oxo-3-phenylpropan-2-yl)pyrazine-2-carboxamide. Grade: 98% by HPLC. CAS No. 289472-80-6. Molecular formula: C14H14N4O2. Mole weight: 270.29.
Borussertib
Borussertib is a covalent-allosteric Akt inhibitor with IC50 of 0.8 nM. Borussertib displays antitumor activity in combination with the MEK inhibitor trametinib in patient-derived xenograft models and provides a starting point for further pharmacokinetic/dynamic optimization. CAS No. 1800070-77-2. Molecular formula: C36H32N6O3. Mole weight: 596.68.
Borussertib
Borussertib, a chemical probe, is a covalent-allosteric and first-in-class inhibitor of protein kinase Akt, with an IC50 of 0.8 nM and a Ki of 2.2 nM for Aktwt[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1800070-77-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122913.
BOS172722
BOS172722 is a potent and selective monopolar spindle 1 (MPS1) checkpoint inhibitor with IC50 of 11 nM. Synonyms: BOS-172722; BOS 172722; N2-(2-Ethoxy-4-(4-methyl-4H-1,2,4-triazol-3-yl)phenyl)-6-methyl-N8-neopentylpyrido[3,4-d]pyrimidine-2,8-diamine. CAS No. 1578245-44-9. Molecular formula: C24H30N8O. Mole weight: 446.55.
BOS-172722
BOS-172722 is an inhibitor of monopolar spindle 1 (MPS1) checkpoint with an IC50 of 11 nM and 63 nM for MPS1 (1 mM ATP) and P-MPS1, respectively. BOS-172722 also has potential for the study of various forms of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1578245-44-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112162.
BOS-318
BOS-318 is a potent, slowly dissociating, highly selective, and cell-permeable furin inhibitor with IC50 value of 1.9 nM. BOS-318 protects ENaC from subsequent activation by neutrophil elastase. BOS-318 can be used for the rsearch for CF lung disease[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2387633-15-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147140.
Bosakitug
Bosakitug (BSI-045B) is an TSLP-targeting IgG1κ type humanized antibody, the recommed isotype control is Human IgG1 kappa, Isotype Control (HY-P99001). Bosakitug can be used in the research of inflammatory diseases such as moderate to severe atopic dermatitis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BSI-045B; TQC2731. CAS No. 2762183-23-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990906.
Boscalid
Boscalid is a succinate dehydrogenase (SDHI) inhibitor with antifungal activity. Boscalid binds to the ubiquinone-binding site of fungal mitochondrial complex II, blocks ATP production and aerobic respiration, exhibits good control efficacy against a variety of plant fungal diseases including gray mold, sclerotinia rot and powdery mildew, and is widely used for disease control in agriculture. Boscalid induces apoptosis, altered lipid metabolism, mitochondrial dysfunction, respiratory impairment, oxidative stress, ROS accumulation and neurodevelopmental disorders in zebrafish. Boscalid reduces foraging ability, shortens median death time and causes chronic toxicity in exposed honeybees. Boscalid also possesses genotoxicity, cytotoxicity, elevated mitochondrial superoxide levels and early-stage apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 188425-85-6. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-119976.
Boscalid-d4
Boscalid-d4 is the deuterium labeled Boscalid. Boscalid is a succinate dehydrogenase (SDHI) inhibitor with antifungal activity. Boscalid binds to the ubiquinone-binding site of fungal mitochondrial complex II, blocks ATP production and aerobic respiration, exhibits good control efficacy against a variety of plant fungal diseases including gray mold, sclerotinia rot and powdery mildew, and is widely used for disease control in agriculture. Boscalid induces apoptosis, altered lipid metabolism, mitochondrial dysfunction, respiratory impairment, oxidative stress, ROS accumulation and neurodevelopmental disorders in zebrafish. Boscalid reduces foraging ability, shortens median death time and causes chronic toxicity in exposed honeybees. Boscalid also possesses genotoxicity, cytotoxicity, elevated mitochondrial superoxide levels and early-stage apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2468796-76-9. Pack Sizes: 1 mg; 5 mg. Product ID: HY-119976S.
Boscalid Metabolite M510F01
Boscalid Metabolite M510F01. Uses: For analytical and research use. CAS No. 661463-87-2. Mole weight: 359.21. Catalog: AP661463872.
Boscalid (Standard)
Boscalid (Standard) is the analytical standard of Boscalid. This product is intended for research and analytical applications. Boscalid is a succinate dehydrogenase (SDHI) inhibitor with antifungal activity. Boscalid binds to the ubiquinone-binding site of fungal mitochondrial complex II, blocks ATP production and aerobic respiration, exhibits good control efficacy against a variety of plant fungal diseases including gray mold, sclerotinia rot and powdery mildew, and is widely used for disease control in agriculture. Boscalid induces apoptosis, altered lipid metabolism, mitochondrial dysfunction, respiratory impairment, oxidative stress, ROS accumulation and neurodevelopmental disorders in zebrafish. Boscalid reduces foraging ability, shortens median death time and causes chronic toxicity in exposed honeybees. Boscalid also possesses genotoxicity, cytotoxicity, elevated mitochondrial superoxide levels and early-stage apoptosis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 188425-85-6. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119976R.
Bosentan
Bosentan is a competitive and dual antagonist of endothelin-1 (ET) for the ETA and ETB receptors with Ki of 4.7 nM and 95 nM in human SMC, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 147536-97-8. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-A0013.
Bosentan
A mixed endothelin receptor antagonist. Used as a vasodilator. Antihypertensive. Group: Biochemicals. Alternative Names: 4-(1,1-Dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2-bipyrimidin]-4-yl]benzenesulfonamide; p-tert-Butyl-N- [6- (2-hydroxyethoxy) -5- (o-methoxyphenoxy) -2- (2-pyrimidinyl) -4-pyrimidinyl] benzenesulfonamide; Actelion; Ro 47-0203; Ro 47-0203/039; Tracleer. Grades: Highly Purified. CAS No. 147536-97-8. Pack Sizes: 100mg, 250mg, 500mg. Molecular Formula: C27H29N5O6S, Molecular Weight: 551.62. US Biological Life Sciences.
Worldwide
Bosentan
Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively. Synonyms: Ro 47-0203. Grade: >98%. CAS No. 147536-97-8. Molecular formula: C27H29N5O6S. Mole weight: 551.61.
Bosentan
1g Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C27H29N5O6S. CAS No. 147536-97-8. Prepack ID 54399509-1g. Molecular Weight 551.61. See USA prepack pricing.