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| Product | Description | |
|---|---|---|
| Bovine Freeze Dried Bone Marrow Powder | Bovine Freeze Dried Bone Marrow Powder. |  CA, FL & NJ |
| Bovine Gelatin,suitable for cell culture | Bovine Gelatin, suitable for cell culture can be used for cell culture to induce cell attachment[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9000-70-8. Pack Sizes: 5 g; 10 g; 25 g; 50 g. Product ID: HY-Y1365D. |  |
| Bovine glu-Plasminogen | Plasminogen is a single chain glycoprotein zymogen which is synthesized in the liver and circulates in plasma at a concentration of approximately 2.4 uM. The plasminogen molecule contains 790 amino acids, 24 disulfide bridges, no free sulfhydryls and 5 regions of internal sequence homology, known as kringles, between Lys77 and Arg560. These five triple-looped, three disulfide bridged, kringle regions are homologous to the kringle domains in t-PA, u-PA and prothrombin. Plasminogen contains one high affinity (Kd=9x10-6M) and four low affinity (Kd=5x10-3M) lysine binding sites. The high affinity binding site resides within the first kringle region of plasminogen. The interaction of p.hich remain covalently associated by a disulfide bond.Native glu-plasminogen is prepared from fresh frozen human plasma by a modification of the procedure of Castellino, utilizing gel filtration and affinity chromatography. The two carbohydrate variants of glu-plasminogen (CHOI and CHOII) are isolated by gradient elution from lysine-Sepharose using the lysine analog, e-aminocaproic acid. The plasminogen is supplied in 50% (vol/vol) glycerol/H2O for storage at -20°C. Purity is determined by SDS-PAGE analysis. Group: Zymogens. Purity: >95% by SDS-PAGE. Plasminogen. Stability: 12 months. Storage: -20°C. Source: Bovine. Bovine glu-Plasminogen; Plasminogen. Pack: 1 mg. Cat No: CZY-015. |  |
| Bovine Heme Iron Polypeptide (HIP) 2% Iron | Bovine Heme Iron Polypeptide (HIP) 2% Iron. | CA, FL & NJ |
| Bovine Hemoglobin Powder | Bovine Hemoglobin Powder. | CA, FL & NJ |
| Bovine Liver Defatted Powder (40 Mesh) | Bovine Liver Defatted Powder (40 Mesh). | CA, FL & NJ |
| Bovine Lung Powder | Bovine Lung Powder. | CA, FL & NJ |
| Bovine Lymphatic Substance Powder | Bovine Lymphatic Substance Powder. | CA, FL & NJ |
| Bovine Lymph Freeze Dried Powder | Bovine Lymph Freeze Dried Powder. | CA, FL & NJ |
| Bovine Neutrophil beta-defensin 5 | Neutrophil beta-defensin 5 is an antimicrobial peptide found in Bos taurus (Bovine), and has antibacterial activity. Synonyms: BNBD 5; Neutrophil beta-defensin 5. Grade: >98%. |  |
| Bovine Orchic Substance Powder | Bovine Orchic Substance Powder. | CA, FL & NJ |
| Bovine Pancreas Tissue Glandular Substance Powder | Bovine Pancreas Tissue Glandular Substance Powder. | CA, FL & NJ |
| Bovine Pancreatin 4X USP | Bovine Pancreatin 4X USP. | CA, FL & NJ |
| Bovine Placenta Powder | Bovine Placenta Powder. | CA, FL & NJ |
| Bovine Plasminogen | Purified from freshly collected bovine plasma. The protein purity is determined by SDS-PAGE and shows no reduction upon incubation with 2-mercaptoethanol. No Plasmin activity is detected using chromogenic substrate S-2251. Plasminogen is activated to the serine protease plasmin via urokinase, streptokinase or tissue plasminogen activator. Group: Zymogens. Purity: >94% by SDS-PAGE. Plasminogen. Mole weight: 90,000-94,000. Stability: 30 months. Storage: 2-8°C. Source: Bovine. Bovine Plasminogen; Plasminogen. Pack: 1mg. Cat No: CZY-030. | |
| Bovine Protein C | The vitamin K-dependent zymogen, protein C, is synthesized in the liver as a single chain polypeptide and is subsequently converted to a disulfide linked heterodimer, by removal of a dipeptide (Lys-146 and Arg-147) from the precursor molecule. Trace quantities of the single chain form have been observed in plasma. The light chain, which is responsible for the calcium dependent binding of protein C to phospholipid vesicles, contains 11 γ-carboxyglutamic acid (gla) residues, 1 b-hydroxyaspartic acid residue, and 2 epidermal growth factor (EGF) homology domains. The serine protease catalytic triad is located in the heavy chain. Human protein C is susceptible to proteolytic cleavag.g the proteolytic inactivation of factors Va and VIIIa. APC also contributes to the fibrinolytic response by complex formation with plasminogen activator inhibitors.Bovine protein C is prepared from fresh citrated bovine plasma by a modification of the Walker procedure, as described by Haley et al. Human protein C is prepared from fresh frozen citrated human plasma using a combination of immunoaffinity chromatography, and conventional techniques. Protein C is provided in 50% (vol/vol) glycerol/H2O and should be stored at -20°C. Purity is determined by SDS-PAGE analysis and activity is measured using a chromogenic substrate based assay. Group: Zymogens. Purity: >95% by SDS-PAGE. Prote. | |
| Bovine Prothrombin | Prothrombin is a vitamin K-dependent plasma protein which is synthesized in the liver. Prior to secretion into plasma, prothrombin undergoes post-translational modification by a vitamin K-dependent carboxylase which converts ten specific glutamic acid residues to γ-carboxyglutamic acid (gla). The ten gla residues are located within the first 40 amino acids of the mature protein and contribute to the ability of prothrombin to bind to negatively charged phospholipid membranes. Prothrombin contains two regions of internal homology which are referred to as "kringle" structures. These regions of conspicuous secondary structure are located between residues 40 and 270 of the mature p.Ser321 (human) / Arg323-Ser324 (bovine) to a "pro" fragment (fragment 1.2) and thrombin, the latter of which is composed of two chains covalently linked by a disulfide bond. In the case of human prothrombin/thrombin, there is an additional thrombin feed-back cleavage at Arg284-Thr285 resulting in an additional 13 amino acids being removed from the mature thrombin A chain.Human prothrombin is prepared from fresh frozen human plasma as described by Bajaj and coworkers. Bovine prothrombin is prepared from fresh bovine plasma using a modification of the procedure described by Owen and coworkers. Purified prothrombin is supplied in 50% (vol/vol) glycerol/H2O and should be stored at -20. | |
| Bovine Serum Albumin | Bovine Serum Albumin. CAS No. 9048-46-8. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| Bovine Serum Albumin | 100g Pack Size. Group: Amino Acids, Analytical Reagents, Biochemicals. Formula: N/A. CAS No. 9048-46-8. Prepack ID 22574477-100g. See USA prepack pricing. |  |
| Bovine Serum Albumin | Bovine Serum Albumin. Uses: For analytical and research use. CAS No. 9048-46-8. EC Number: 232-936-2. Catalog: AP9048468. |  |
| Bovine Serum Albumin | Bovine Serum Albumin (BSA) is a 583-residue protein consisting of three homologous all-α domains, organized in a heart-shaped structure. BSA is a globular protein that is used in numerous biochemical applications. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Albumin bovine serum; BSA. CAS No. 9048-46-8. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-D0842. | |
| Bovine Serum Albumin (Biotinylated) | Bovine Serum Albumin (Biotinylated) is a biotinylated bovine serum albumin that selectively binds to different vascular subsets in lymphoid tissue. Bovine Serum Albumin (Biotinylated) can be used as a histochemical probe, and a targeting ligand for drug delivery[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9048-46-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-NP002D. | |
| Bovine Serum Albumin (Low Endotoxin,Fatty acid free) | Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) is a 583 amino acid globular protein and oligonucleotide binding protein composed of three homologous full α domains. Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) blocks the overall binding of oligonucleotides to cells. Bovine Serum Albumin (Low Endotoxin,Fatty acid free) (BSA) regulates the development of hamster embryos and induces arthritis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Albumin bovine serum (Low Endotoxin,Fatty acid free); BSA (Low Endotoxin,Fatty acid free). CAS No. 9048-46-8. Pack Sizes: 1 g; 5 g; 10 g; 25 g. Product ID: HY-D0842A. | |
| Bovine Serum Albumin solution | Bovine Serum Albumin solution. Uses: For analytical and research use. CAS No. 9048-46-8. Catalog: AP9048468-A. | |
| Bovine Serum Protein Concentrate Powder | Bovine Serum Protein Concentrate Powder. | CA, FL & NJ |
| Bovine Spleen Substance Powder | Bovine Spleen Substance Powder. | CA, FL & NJ |
| Bovine Superoxide dismutase-polyethylene glycol | Superoxide dismutases (SOD) are enzymes that alternately catalyze the dismutation (or partitioning) of the superoxide (O2-) radical into either ordinary molecular oxygen (O2) or hydrogen peroxide (H2O2). Superoxide is produced as a by-product of oxygen metabolism and, if not regulated, causes many types of cell damage. Hydrogen peroxide is also damaging, but less so, and is degraded by other enzymes such as catalase. Thus, SOD is an important antioxidant defense in nearly all living cells exposed to oxygen. One exception is Lactobacillus plantarum and related lactobacilli, which use a different mechanism to prevent damage from reactive (O2-). Group: Enzymes. Synonyms: PEG-SOD; Superoxide dismutase-polyethylene glycol; SOD-PEG. SOD. Activity: 11,000 units/mg SOD before conjugation; SOD/PEG ratio: 10-20 PEG with each SOD enzyme. Appearance: Off-white. Storage: Store at -20°C. Form: Lyophilized powder. Source: Bovine Kidney. Species: Bovine. PEG-SOD; Superoxide dismutase-polyethylene glycol; SOD-PEG. Cat No: NATE-0682. | |
| Bovine tendon powder | Bovine tendon powder. CAS No. 9007-34-5. |  |
| Bovine Thymus Powder Thymomodulin 99% HPLC | Bovine Thymus Powder Thymomodulin 99% HPLC. | CA, FL & NJ |
| Bovine Thymus Substance Powder | Bovine Thymus Substance Powder. | CA, FL & NJ |
| Bovine Thyroid Freeze Dried Powder | Bovine Thyroid Freeze Dried Powder. | CA, FL & NJ |
| Bovine Thyroid Thyroxin Free Powder | Bovine Thyroid Thyroxin Free Powder. | CA, FL & NJ |
| Bovinocidin | Bovinocidin is a fatty acid derivative produced by Streptomyces sp., Aspergillus avenaceus, Asp. flavust, Asp. oryzae and Penicillum atrovenetum. The minimum inhibitory concentration for BCG tuberculosis (BCG) is 50-100 ?/mL. Uses: Antihypertensive agents. Synonyms: Hiptagenic acid. Grade: >98%. CAS No. 504-88-1. Molecular formula: C3H5NO4. Mole weight: 119.08. | |
| Box5 | Box5 is a potent Wnt5a antagonist. Box5 inhibits Wnt5a signaling and inhibits Wnt5a-mediated Ca2+ release. Box5 inhibits cell migration. Box5 has the potential for the research of melanoma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1206604-29-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-123071. | |
| Boxazomycin A | Boxazomycin A is an antibiotic produced by Pseudonocardia sp.G495-11. It has activity against gram-positive bacteria and anaerobic bacteria. Synonyms: 4-Benzoxazolecarboxamide, 5-hydroxy-2-(5-hydroxy-2-(hydroxymethyl)-4-pyrimidinyl)-7-methyl-; (2Z)-5-hydroxy-2-[2-(hydroxymethyl)-5-oxopyrimidin-4-ylidene]-7-methyl-3H-1,3-benzoxazole-4-carboxamide. CAS No. 107021-64-7. Molecular formula: C14H12N4O5. Mole weight: 316.27. | |
| Boxazomycin B | Boxazomycin B is an antibiotic produced by Pseudonocardia sp.G495-11. It has activity against gram-positive bacteria and anaerobic bacteria. CAS No. 107021-65-8. Molecular formula: C14H12N4O4. Mole weight: 300.27. | |
| Boxazomycin C | Boxazomycin C is an antibiotic produced by Pseudonocardia sp.G495-11. It has activity against gram-positive bacteria and anaerobic bacteria. CAS No. 107021-66-9. Molecular formula: C14H12N4O4. Mole weight: 300.27. | |
| Bozitinib | Bozitinib (PLB-1001) is a highly selective c-MET kinase inhibitor with blood-brain barrier permeability. Bozitinib (PLB-1001) is a ATP-competitive small-molecule inhibitor, binds to the conventional ATP-binding pocket of the tyrosine kinase superfamily[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PLB-1001; CBT-101; Vebreltinib. CAS No. 1440964-89-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125017. | |
| BP-1-102 | BP-1-102 is an orally available, small-molecule inhibitor of transcription factor Stat3, with an IC50 of 6.8 μM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1334493-07-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-100493. | |
| BP-1-102 | BP-1-102 is a potent and selective STAT3 inhibitor. BP-1-102 inhibits the expression of genes including c-Myc, Cyclin D1, Bcl-xL, Survivin, VEGF, and Krüppel-like factor 8, which is related to the STAT3-mediated breast tumor growth and migration. Synonyms: 4-(N-(4-cyclohexylbenzyl)-2-(2,3,4,5,6-pentafluoro-N-methylphenylsulfonamido)acetamido)-2-hydroxybenzoic acid. Grade: >98%. CAS No. 1334493-07-0. Molecular formula: C29H27F5N2O6S. Mole weight: 626.595. | |
| BP-2 Bipolar Membrane | BP-2 Bipolar Membrane. Product ID: ACIR-HP007. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| BP 554 | BP 554 is a selective 5-HT1A agonist. Synonyms: Piperazine, 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenyl-; 1-(3-(Benzo[d][1,3]dioxol-5-yloxy)propyl)-4-phenylpiperazine; BP554; BP-554; LASSBio 670; 1-(3-(3,4-Methylenedioxyphenoxy)propyl)-4-phenylpiperzine. Grade: ≥95%. CAS No. 82900-57-0. Molecular formula: C20H24N2O3. Mole weight: 340.42. | |
| BP 554 maleate | BP 554 maleate. Group: Biochemicals. Grades: Purified. CAS No. 1221401-95-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| BP 554 maleate | BP 554 maleate is a selective 5-HT1A agonist. Synonyms: Piperazine, 1-[3-(1,3-benzodioxol-5-yloxy)propyl]-4-phenyl-, (2Z)-2-butenedioate (1:1); 1-(3-(Benzo[d][1,3]dioxol-5-yloxy)propyl)-4-phenylpiperazine maleate; 1-[3-(3,4-methylenedioxyphenoxy)propyl]-4-phenylpiperazine maleate. Grade: ≥99% by HPLC. CAS No. 1221401-95-1. Molecular formula: C20H24N2O3.C4H4O4. Mole weight: 456.48. | |
| BP79 | BP79 is a potent TSLP receptor inhibitor. BP79 disrupts TSLP-mediated ternary complex formation, blocks TSLPR-IL7Rα co-localization, binds and stabilizes TSLPR, and inhibits phosphorylated STAT3/6. BP79 suppresses immune cell infiltration, secretion of IL-13, IL-4. BP79 can be used for the research of inflammation diseases, such as atopic dermatitis, allergic asthma, and allergic rhinitis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3104965-33-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-206870. | |
| BP 897 | BP 897, a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist, has a high affinity for the dopamine D3 receptor (Ki = 0.92 nM) and a 70 times lower affinity for the D2 receptor (Ki = 61 nM). It shows selective inhibition of cocaine-seeking behavior. Uses: Dopamine agonists. Synonyms: 2-Naphthalenecarboxamide, N-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-; BP-897; BP897; N-[4-(4-(2-Methoxyphenyl)piperazinyl)butyl]-2-naphthamide; N-(4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide. CAS No. 192384-87-5. Molecular formula: C26H31N3O2. Mole weight: 417.54. | |
| BP 897 hydrochloride | BP 897 hydrochloride, a potent and partial dopamine D3 receptor agonist and a weak D2 receptor antagonist, has a high affinity for the dopamine D3 receptor (Ki = 0.92 nM) and a 70 times lower affinity for the D2 receptor (Ki = 61 nM). It shows selective inhibition of cocaine-seeking behavior. Uses: Dopamine agonists. Synonyms: 2-Naphthalenecarboxamide, N-(4-(4-(2-methoxyphenyl)-1-piperazinyl)butyl)-, monohydrochloride; N-(4-(4-(2-Methoxyphenyl)piperazin-1-yl)butyl)-2-naphthamide hydrochloride; N-{4-[4-(2-Methoxyphenyl)-1-piperazinyl]butyl}-2-naphthamide hydrochloride (1:1). Grade: ≥95%. CAS No. 314776-92-6. Molecular formula: C26H32ClN3O2. Mole weight: 454.00. | |
| BPA(10)EODA | BPA(10)EODA. Mole weight: 776. | |
| BPA(10)EODMA | BPA(10)EODMA. Mole weight: 808. | |
| BPA12PO6EODA | BPA12PO6EODA. Mole weight: 1296. | |
| BPA(12)PO(6)EODA | BPA(12)PO(6)EODA. Mole weight: 1296. | |
| BPA(2)EODA | BPA(2)EODA. Mole weight: 424. | |
| BPA(2)EODMA | BPA(2)EODMA. Mole weight: 424. | |
| BPA(3)EODA | BPA(3)EODA. Mole weight: 468. | |
| BPA(4)EODA | BPA(4)EODA. Mole weight: 512. | |
| BPA(4)EODMA | BPA(4)EODMA. Mole weight: 532. | |
| BPAM344 | BPAM344 is a kainate receptor (KAR) subunits GluK1b, GluK2a, and GluK3a positive allosteric modulator (PAM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1204572-55-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129086. | |
| BPC 157 | BPC 157 is the 15-amino acide fragment of gastric peptide BPC. BPC 157 exhibits wound healing promoting and neuroprotective activity. BPC 157 maintains the integrity of the gastrointestinal mucosa without significant toxicity. BPC 157 acetate counteracts NSAIDs/insulin overdose/copper-induced toxicity. BPC 157 ameliorates specific (over)stimulated/damaged neurotransmitter systems-induced behavioral disorders through serotonergic and dopaminergic systems[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 137525-51-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105174. | |
| BPC 157 acetate | BPC 157 acetate is an orally active peptide. BPC 157 acetate exhibits multiple activities such as promoting wound healing, tendon healing, neuroprotection, and gastrointestinal protection. BPC 157 acetate can be used in the research of tendon injury, burn, gastric ulcer, and neurological diseases[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1628202-19-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105174A. | |
| BPC 157 acetate | BPC 157 acetate is a synthetic pentadecapeptide that is beneficial for the treatment of ulcers in the stomach, intestinal damage such as fistulas and inflammatory disorders, bone and joint healing and growth rates, and organ damage. Uses: Bpc 157 acetate is a peptide inhibitor, a serine-proline peptide produced by gastric mucosal smooth muscle cells in vivo. it has attracted the interest of researchers and has shown potential in the field of drug development. the main mechanisms of action of bpc 157 acetate include promoting healing, anti-inflammatory and antioxidant activities, which make it have a wide range of application potent. Synonyms: H-Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val-OH.CH3CO2H; glycyl-L-alpha-glutamyl-L-prolyl-L-prolyl-L-prolyl-glycyl-L-lysyl-L-prolyl-L-alanyl-L-alpha-aspartyl-L-alpha-aspartyl-L-alanyl-glycyl-L-leucyl-L-valine acetic acid. Grade: ≥95%. CAS No. 216441-37-1. Molecular formula: C64H102N16O24. Mole weight: 1479.61. | |
| BPD-Ring B | BPD-Ring B is a product from the synthesis of verteporfinin. It can be used for making porphyrin-related dye, nanoparticles, photosensitizers, and other photodymanic therapeutic drugs. Uses: Make porphyrin-related dye, nanoparticles, photosensitizers, and other photodymanic therapeutic drugs. Synonyms: BPD-B; Benzoporpyrin Ring B derivative; 23H,25H-Benzo[b]porphine-9,13- dipropanoic acid, 19-ethenyl-1,22a-dihydro-1,2-bis(methoxycarbonyl)-8,14,18, 22a-tetramethyl-, dimethyl ester. Grade: 98%. CAS No. 143986-17-8. Molecular formula: C42H44N4O8. Mole weight: 732.83. | |
| BP Fluor 488 cadaverine | BP Fluor 488 Cadaverine is a carboxyl/carbonyl reactive building block used widely to modify carboxylic groups in the presence of activators (e.g. EDC or DCC) or activated esters (e.g. NHS esters) through a stable amide bond. Uses: Scientific research. Category: Signaling pathways. CAS No. 1178534-61-6. Pack Sizes: 1 mg. Product ID: HY-D2751. | |
| BP Fluor 488 DBCO | BP Fluor 488 DBCO is a popular labeling dye used in copper-free Click Chemistry reactions. It will react with the azide group in antibody, proteins, peptides, amino-modified oligos, and other target molecules. The dye has an excitation peak at 499 nm and an emission peak at 520 nm. The conjugates are widely used in microscopy, flow cytometry, and other applications. BP Fluor 488 is a pure 5-sulfonated rhodamine molecule and it eliminates the lot-to-lot variation caused by two isomers ratio differences. Uses: Scientific research. Category: Signaling pathways. CAS No. 2423960-92-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-W800680. | |
| BPH-1358 | BPH-1358 is a potent inhibitor of human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) with IC50s of 1.8 μM and 110 nM, respectively. It has activity against Staphylococcus aureus in vitro (MIC ~250 ng/mL). Synonyms: TS-07705; HY-118946. CAS No. 5352-53-4. Molecular formula: C32H30Cl2N6O2. Mole weight: 601.5. | |
| BPH-1358 free base | BPH-1358 free base is a potent inhibitor of human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) with IC50s of 1.8 μM and 110 nM, respectively. It has activity against Staphylococcus aureus in vitro (MIC ~250 ng/mL). Synonyms: NSC 50460 free base; N,N'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]biphenyl-4,4'-dicarboxamide; N,N'-Bis[3-(4,5-dihydro-1H-imidazole-2-yl)phenyl]-1,1'-biphenyl-4,4'-dicarboxamide; [1,1'-Biphenyl]-4,4'-dicarboxamide, N4,N4'-bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-; N,N'-Bis[3-(4,5-dihydro-1H-imidazol-2-yl)phenyl]-4,4'-biphenyldicarboxamide. Grade: ≥95%. CAS No. 801985-13-7. Molecular formula: C32H28N6O2. Mole weight: 528.60. | |
| BPH-1358 mesylate | BPH-1358 mesylate is a potent human farnesyl diphosphate synthase (FPPS) and undecaprenyl diphosphate synthase (UPPS) inhibitor. BPH-1358 mesylate is active against S. aureus in vitro (MIC ~250 ng/mL). Synonyms: NSC50460 mesylate. Molecular formula: C34H36N6O8S2. Mole weight: 720.82. | |
| BPH-652 | BPH-652, also known as BMS-187745, has been found to be a SQS inhibitor that could probably be effective against S. aureus infections. Synonyms: BMS-187745; BPH-652; BMS 187745; BPH 652; BMS187745; BPH652; CHEMBL351151; BMS 188745 Potassium Salt; DNC009027; KB-75764; tripotassium; 4-(3-phenoxyphenyl)-1-phosphonatobutane-1-sulfonate. Grade: 98%. CAS No. 157124-84-0. Molecular formula: C16H16K3O7PS. Mole weight: 500.63. | |
| BPH-652 | BPH-652 is a S. aureus dehydrosqualene synthase (CrtM) inhibitor, with a Ki of 1.5 nM and an IC50 of 100-300 nM (S. aureus pigment formation)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 157124-84-0. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16115. | |
| BPH715 | BPH715 is a new generation of lipophilic bisphosphonates. It is potent in cell culture and effectively inhibited tumor cell growth and invasiveness. It is used as anticancer agents that block protein prenylation also have potent activity against Plasmodium liver stages. It has activity against a Plasmodium geranylgeranyl diphosphate synthase (GGPPS), as well as low nM activity against human farnesyl and geranylgeranyl diphosphate synthases. It is used to treat bone resorption diseases and has activity against a broad range of protists, including blood-stage Plasmodium spp. Uses: Bph715 is used as anticancer agents that block protein prenylation also have potent activity against plasmodium liver stages. it is also used to treat bone resorption diseases and has activity against a broad range of protists. Synonyms: BPH-715; BPH 715; BPH715; GTPL3196; GTPL 3196; GTPL-3196; Bisphpshonate-715. 3-(Decyloxy)-1-(2-hydrogen phosphonato-2-phosphonoethyl)pyridin-1-ium; Bisphpshonate-715; [2-(3-Decoxypyridin-1-ium-1-yl)-1-phosphonoethyl]-hydroxyphosphinate; Hydrogen (2-(3-(decyloxy)pyridin-1-ium-1-yl)-1-phosphonoethyl)phosphonate. Grade: >98%. CAS No. 1059677-23-4. Molecular formula: C17H31NO7P2. Mole weight: 423.38. | |
| BPHA | BPHA is a potent and orally active MMP-2, MMP-9 and MMP-14 inhibitor with IC50s of 12 nM, 16 nM and 17 nM, respectively. BPHA does not inhibit MMP-1, -3, and -7 (the IC50s are 974, >1000, and 795 nM, respectively). BPHA has antiangiogenic and antitumor effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 193807-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114785. | |
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