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Braco-19 is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 351351-75-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15523.
Braco-19
Braco-19 is a potent telomerase/telomere inhibitor that prevents telomerase catalysis. Braco-19, as a G-quadruplex (GQ) binding ligand, stabilizes GQ formation at 3V telomeric DNA overhang and produces rapid senescence or selective cell death. It is also an HAdV virus replication inhibitor. Uses: Cytostatic agents. Synonyms: N-(9-{[4-(dimethylamino)phenyl]amino}-6-[3-(pyrrolidin-1-yl)propanamido]acridin-3-yl)-3-(pyrrolidin-1-yl)propanamide; N,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamide; 9-[4-(N,N-dimethylamino)phenylamino]-3,6-bis(3-pyrrolodinopropionamido)acridine. Grade: ≥95%. CAS No. 351351-75-2. Molecular formula: C35H43N7O2. Mole weight: 593.76.
Braco-19 trihydrochloride
Braco-19 trihydrochloride is a potent telomerase/telomere inhibitor, preventing the capping and catalytic action of telomerase. Braco-19 acts as G-quadruplex (GQ) binding ligand, stabilizing G-quadruplexes formation at the 3V telomeric DNA overhang and produce rapid senescence or selective cell death. Braco-19 is also a HAdV virus replication inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1177798-88-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15523A.
BRACO 19 trihydrochloride
BRACO 19 trihydrochloride is a telomerase inhibitor (IC50 = 115 nM) that suppresses the expression of human telomerase reverse transcriptase (hTERT) and induces cellular senescence. BRACO 19 was shown to inhibit growth of uterine cancer cells in vitro and growth of uterine tumor xenografts in mice. Synonyms: N,N'-[9[[4-(Dimethylamino)phenyl]amino]-3,6-acridinediyl]bis-1-pyrrolidinepropanamide trihydrochloride. Grade: ≥95% by HPLC. CAS No. 1177798-88-7. Molecular formula: C35H43N7O2.3HCl. Mole weight: 703.14.
Bractoppin
Bractoppin is a potent and selective inhibitor of phosphopeptide recognition by the BRCA1 tBRCT domain. Bractoppin interrupts BRCA1 tBRCT-dependent cellular signals evoked by DNA damage. Bractoppin selectively inhibits substrate binding with nanomolar potency in vitro. Grade: 99%. CAS No. 2290527-07-8. Molecular formula: C25H23FN4O. Mole weight: 414.47.
Bradanicline
Bradanicline (TC-5619) is an orally active agonist of α7 nAChR with moderate blood-brain barrier penetration. Bradanicline exhibits high affinity and subtype selectivity for human α7 nAChR. Bradanicline possesses antitussive activity that depends on sustained receptor binding and activation. Bradanicline requires systemic administration to dose-dependently inhibit cough induced by citric acid, bradykinin and inhaled nicotine. Bradanicline is well tolerated in preclinical studies and is widely used in research related to chronic refractory cough[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TC-5619. CAS No. 639489-84-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18060.
Bradanicline
Bradanicline acts as a partial agonist at the α7 subtype of the neural nicotinic acetylcholine receptors. It showed cognitive enhancing effects in animal studies, and was used as a potential treatment for schizophrenia and attention deficit disorder. It was used for Alzheimer's disease and cognitive impairment, but was discontinued. It was being developed by Targacept and was in phase II trials, but now it is terminated. Uses: Bradanicline was used as a potential treatment for schizophrenia and attention deficit disorder. it was used for alzheimer's disease and cognitive impairment. Synonyms: TC-5619; TC 5619; TC5619; N-[(2S,3R)-2-(pyridin-3-ylmethyl)-1-azabicyclo[2.2.2]octan-3-yl]-1-benzofuran-2-carboxamide; TC-5619-023; TC5619-023. Grade: 98%. CAS No. 639489-84-2. Molecular formula: C22H23N3O2. Mole weight: 361.44.
Bradanicline hydrochloride
Bradanicline hydrochloride is Alpha-7 Nicotinic Receptor Agonist. It showed cognitive enhancing effects in animal studies, and was being developed as a potential treatment for schizophrenia and attention deficit disorder. It was discontinued for Alzheimer's disease and cognitive impairment in schizophrenia in late 2013. It was also discontinued for ADHD, and no longer seems to be being developed. Uses: Bradanicline hydrochloride was being developed as a potential treatment for schizophrenia and attention deficit disorder. Synonyms: TC-5619; TC5619; TC-5619-023; TC5619-023; N-((2S,3R)-2-(pyridin-3-ylmethyl)quinuclidin-3-yl)benzofuran-2-carboxamide hydrochloride. Grade: >98%. CAS No. 1111941-90-2. Molecular formula: C22H24ClN3O2. Mole weight: 397.90.
Bradykinin
Bradykinin is a nonapeptide messenger produced from kallidin in the blood. Bradykinin has the selectivity for B2 over B1 receptors. It exhibits hypotensive and anti-inflammatory properties. Uses: Hypotensive agent. Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; L-Bradykinin; Kallidin I; Callidin I; Kallidin 9. Grade: ≥95%. CAS No. 58-82-2. Molecular formula: C50H73N15O11. Mole weight: 1060.21.
Bradykinin
Bradykinin is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58-82-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0206.
Bradykinin 1-3
Bradykinin 1-3, a 3-amino acid residue peptide fragment of Bradykinin, is an amino-truncated Bradykinin cleaved by Prolyl endopeptidase. Synonyms: Bradykinin (1-3); Arginyl-prolyl-proline; arginylprolylproline; L-Arginyl-L-prolyl-L-proline; H-RPP-OH. Grade: 95%. CAS No. 23815-91-0. Molecular formula: C16H28N6O4. Mole weight: 368.43.
Bradykinin (1-5)
Bradykinin (1-5) is a major stable metabolite of Bradykinin (HY-P0206), formed by the proteolytic action of angiotensin-converting enzyme (ACE)[1]. Bradykinin (1-5) inhibits α- and γ-thrombin-induced platelet aggregation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 23815-89-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P1488.
Bradykinin 1-5
Bradykinin 1-5 is the main stable metabolite of Bradykinin and is formed by proteolysis of angiotensin-converting enzyme (ACE). Synonyms: H-RPPGF-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanine; Bradykinin (1-5); Bradykinin Fragment 1-5; 1-5-Bradykinin (9Cl); N-[2-({[1-(Arginylprolyl)pyrrolidin-2-yl](hydroxy)methylidene}amino)-1-hydroxyethylidene]phenylalanine. Grade: ≥95%. CAS No. 23815-89-6. Molecular formula: C27H40N8O6. Mole weight: 572.66.
Bradykinin (1-6)
Bradykinin (1-6) is an amino-truncated Bradykinin peptide. Bradykinin (1-6) is a stable metabolite of Bradykinin, cleaved by carboxypeptidase Y (CPY). Uses: Scientific research. Category: Signaling pathways. CAS No. 23815-88-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1469.
Bradykinin 1-6
Bradykinin 1-6, a stable metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by carboxypeptidase Y (CPY). Synonyms: H-Arg-Pro-Pro-Gly-Phe-Ser-OH; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-serine; (S)-2-((S)-2-(2-((S)-1-((S)-1-((S)-2-amino-5-guanidinopentanoyl)pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)acetamido)-3-phenylpropanamido)-3-hydroxypropanoic acid; Bradykinin (1-6). Grade: 95%. CAS No. 23815-88-5. Molecular formula: C30H45N9O8. Mole weight: 659.73.
Bradykinin (1-7)
Bradykinin (1-7) is an amino-truncated Bradykinin peptide. Bradykinin (1-7) is a metabolite of Bradykinin, cleaved by endopeptidase. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bradykinin Fragment 1-7. CAS No. 23815-87-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P1484.
Bradykinin 2-9
Bradykinin 2-9, a metabolite of Bradykinin, is an amino-truncated Bradykinin peptide cleaved by Aminopeptidase P. Synonyms: Des-Arg1-bradykinin; H-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH; L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine; Bradykinin fragment 2-9; 2-9-Bradykinin. Grade: ≥95%. CAS No. 16875-11-9. Molecular formula: C44H61N11O10. Mole weight: 904.02.
Bradykinin acetate
Bradykinin acetate is an effective endothelium-dependent vasodilator that can lower blood pressure. Bradykinin acetate can induce contraction of bronchial and intestinal non-vascular smooth muscle, increase vascular permeability, and participate in the mechanism of pain[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 6846-3-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0206A.
Bradykinin acetate salt
Bradykinin Acetate is a physiologically and pharmacologically active peptide of kinin histone, which is composed of nine amino acids. The pharmacological properties of bradykinin include smooth muscle contraction, vasodilation and hypotension, increased capillary permeability, edema formation and pain induction. It can cause bronchoconstriction and rhinitis symptoms of nasal irritation in asthmatics. Synonyms: Bradykinin, acetate (1:x); Bradykinin, acetate (salt); H 1970; H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH.xCH3CO2H; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine acetate salt; L-Bradykinin acetate salt; Arginine, N2-[N-[1-[N-[N-[N-[1-(1-arginyl-L-prolyl)-L-prolyl]glycyl]-3-phenylalanyl]seryl]prolyl]-3-phenylalanyl]-, acetate salt; Bradykinin acetate. Grade: ≥95%. CAS No. 6846-3-3. Molecular formula: C50H73N15O11.xC2H4O2. Mole weight: 1060.21 (free base).
Bradykinin Fragment 1-7
Bradykinin Fragment 1-7 is a seven-membered oligopeptide. Synonyms: Arg-Pro-Pro-Gly-Phe-Ser-Pro; Des-8,9-BK. Grade: ≥97% by HPLC. CAS No. 23815-87-4. Molecular formula: C35H52N10O9. Mole weight: 756.85.
Bradykinin-GN_4 antimicrobial peptide precursor
Bradykinin-GN_4 antimicrobial peptide precursor is originally from Amolops granulosus.
Bradykinin-TR1 bradykinin-related peptide precursor is originally from Amolops granulosus.
Bradykinin triacetate
Bradykinin triacetate is a non-peptide messenger that is enzymatically produced from KALLIDIN in the blood. It is a potent but short-lived agent of arteriolar dilation and increased capillary permeability. Synonyms: Bradykinin, acetate (1:3); Bradykinin, triacetate (salt); Arginine, N2-[N-[1-[N-[N-[N-[1-(1-L-arginyl-L-prolyl)-L-prolyl]glycyl]-3-phenyl-L-alanyl]-L-seryl]-L-prolyl]-3-phenyl-L-alanyl]-, triacetate; Bradykinin acetate; H-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH.3CH3CO2H; L-arginyl-L-prolyl-L-prolyl-glycyl-L-phenylalanyl-L-seryl-L-prolyl-L-phenylalanyl-L-arginine acetic acid. Grade: ≥95%. CAS No. 5979-11-3. Molecular formula: C50H73N15O11.3C2H4O2. Mole weight: 1240.38.
B-Raf IN 1
B-Raf IN 1 is a highlt potent and selective B-Raf inhibitor. It was equipotent against c-Raf. Synonyms: B-Raf-IN-1; B-Raf-IN 1; B-Raf-IN1; MDK36057; MDK-36057; MDK 36057. Grade: >98%. CAS No. 950736-05-7. Molecular formula: C29H24F3N5O. Mole weight: 515.53.
B-Raf IN 2
B-Raf IN 2 is a potent and selective BRAF inhibitor extracted from patent WO2021116055A1, compound Ia. CAS No. 2649372-20-1. Molecular formula: C20H17F2N5O4S. Mole weight: 461.44.
B-Raf inhibitor
aA B-Raf inhibitor, pyrazine and pyrrolo[2,3-b]pyridine derivatives, useful in the treatment of cancer and proliferative diseases. Synonyms: Benzamide, N-[4-[(4-ethyl-1-piperazinyl)methyl]-3-(trifluoromethyl)phenyl]-4-methyl-3-[(6-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-yl)oxy]-. Grade: >98%. CAS No. 1315330-11-0. Molecular formula: C29H31F3N6O2. Mole weight: 552.59.
B-Raf inhibitor 1
B-Raf inhibitor 1 is a potent and selective B-Raf inhibitor with cell IC50s of 0.31 μM and 2 nM for A375 proliferation and A375 p-ERK respectively. Synonyms: B-Raf Inhibitor 1; B-Raf-Inhibitor 1; B-Raf-Inhibitor-1; MDK0403; MDK-0403; MDK 0403. Grade: >98%. CAS No. 1093100-40-3. Molecular formula: C26H19ClN8. Mole weight: 478.94.
B-Raf inhibitor 1 dihydrochloride
B-Raf inhibitor 1 is an inhibitor of B-Raf kinase with IC50 values of 0.31μM and 0.72μM for cell proliferation, respectively in A375 and HCT116. B-Raf is important in signal transduction and some mutant B-Raf occurs in cancer cells. The most common mutation of these is V600E, which makes B-Raf kinase constitutively active. B-Raf inhibitor 1 belongs to the type IIA inhibitors and binds to the DFG-out ATP-binding site of B-Raf. The selectivity of B-Raf inhibitor 1 is less than of other type inhibitors. Besides mutant B-Raf, it can also inhibit wild type B-Raf and other tyrosine kinase. In cells with wild type B-Raf, B-Raf inhibitor 1 can activate the RAF-MEK-ERK signaling pathway via Raf dimerization. The preclinical toxicity test shows B-Raf inhibitor 1 can induce hyperplasia in a mouse model. Synonyms: 1,5-Isoquinolinediamine, N1-(4-chlorophenyl)-6-methyl-N5-[3-(9H-purin-6-yl)-2-pyridinyl]-, hydrochloride (1:2). Grade: >98%. CAS No. 1191385-19-9. Molecular formula: C26H21Cl3N8. Mole weight: 551.86.
Br-AFP1
Br-AFP1 is originally from Brassica rapa subsp. chinensis.
Braftide
Braftide is an allosteric inhibitor for BRAF kinase by targeting the dimer interface of BRAF kinase and inhibiting the formation of BRAF dimers. Braftide inhibits wild-type BRAF and oncogenic BRAFG469A with IC50 of 364 nM and 172 nM, respectively. Braftide inhibits MAPK signaling pathway, inhibits proliferation of KRAS mutant tumor cells (EC50 is 7.1 and 6.6 μM, for HCT116 and HCT-15), in combination of TAT sequence. Braftide can be used for cancer research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2411851-64-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P10436.
Brain Derived Basic Fibroblast Growth Factor (1-24) (FGF basic 1-24) is a synthetic peptide, shows anti-bacterial and anti-HBV activities. Brain Derived Basic Fibroblast Growth Factor (1-24) can be used in infection disease and immune disease research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: FGF basic (1-24). CAS No. 211362-85-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P3601.
Brain Extract Polar
Brain Extract Polar. Alternative Names: Brain Polar Lipid Extract (Porcine). CAS No. 86088-88-2. Product ID: ALCFA86088882. Alfa Chemistry - ISO 9001:32057 Certified.
Brain Extract Total
Brain Extract Total. Alternative Names: Brain Total Lipid Extract (Porcine). CAS No. 86088-88-2. Product ID: ALCFA86088882-1. Alfa Chemistry - ISO 9001:32057 Certified.
Brain natriuretic peptide
A brain natriuretic peptide secreted by the human heart in response to cardiac volume or pressure. Synonyms: Natriuretic factor, brain; Atrial natriuretic peptide B; B-Type natriuretic peptide; BNP; Brain natriuretic factor. Grade: ≥98%. CAS No. 114471-18-0. Molecular formula: C145H248N50O44S4. Mole weight: 3524.1.
Brain natriuretic peptide (1-32) (human)
An agonist at atrial natriuretic peptide (ANP) receptor A (NRP1) which is secreted from cardiac ventricles in response to volume increase and pressure overload. It exhibits natriuretic, vasodilatory and lusitropic activity and suppresses sympathetic and renin-angiotensin-aldosterone systems in vivo, and decreases de novo collagen synthesis as well as increases MMP gene expression in vitro. Synonyms: Brain Natriuretic Peptide-32 human; BNP-32 (human); Nesiritide; H-Ser-Pro-Lys-Met-Val-Gln-Gly-Ser-Gly-Cys(1)-Phe-Gly-Arg-Lys-Met-Asp-Arg-Ile-Ser-Ser-Ser-Ser-Gly-Leu-Gly-Cys(1)-Lys-Val-Leu-Arg-Arg-His-OH; L-seryl-L-prolyl-L-lysyl-L-methionyl-L-valyl-L-glutaminyl-glycyl-L-seryl-glycyl-L-cysteinyl-L-phenylalanyl-glycyl-L-arginyl-L-lysyl-L-methionyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-L-seryl-L-seryl-L-seryl-L-seryl-glycyl-L-leucyl-glycyl-L-cysteinyl-L-lysyl-L-valyl-L-leucyl-L-arginyl-L-arginyl-L-histidine (10->26)-disulfide. Grade: ≥99% by HPLC. CAS No. 124584-08-3. Molecular formula: C143H244N50O42S4. Mole weight: 3464.04.
Brain Natriuretic Peptide (1-32) (human) trifluoroacetate salt
Brain natriuretic peptide (BNP) (1-32) is an endogenous peptide that has cardiovascular functions and belongs to the family of natriuretic peptides. It is an agonist of natriuretic peptide receptors (NPRs) 1 and 3 with Kd values of 7.3 and 13 pM, respectively. It also binds to human recombinant NPR1 and NPR3 with IC50 values of 8 and 2.6 nM, respectively. It also relaxes contractions induced by prostaglandin F2α (PGF2α) in isolated porcine coronary artery and rat aortic strips (IC50s = 0.02 and 12.1 nM, respectively). Synonyms: BNP (1-32) (human). Grade: ≥95%. Molecular formula: C143H244N50O42S4·xCF3COOH. Mole weight: 3464.04.
Brain Natriuretic Peptide-32 rat
Brain Natriuretic Peptide-32 rat. Uses: For analytical and research use. CAS No. 133448-20-1. Mole weight: 3452.94. Catalog: AP133448201.
Brain Natriuretic Peptide-45, mouse
Brain Natriuretic Peptide-45, mouse (BNP-45, mouse) is a 45-amino-acid peptide derived from the mouse BNP prohormone, which exhibits natriuretic, diuretic, and vasoactive effects. Brain Natriuretic Peptide-45, mouse contains all amino acid residues deemed critical for the biological activity of natriuretic peptides. Brain Natriuretic Peptide-45, mouse possesses hypotensive and diuretic activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BNP-45, mouse. CAS No. 1816939-52-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2469.
Brain Natriuretic Peptide (BNP) (1-32), rat
Brain Natriuretic Peptide (BNP) (1-32), rat is a 32-amino acid polypeptide secreted by the ventricle in response to overstretching of cardiomyocytes. Synonyms: Brain Natriuretic Peptide-32 (rat); BNP (1-32), rat; H-Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys(1)-Phe-Gly-Gln-Lys-Ile-Asp-Arg-Ile-Gly-Ala-Val-Ser-Arg-Leu-Gly-Cys(1)-Asp-Gly-Leu-Arg-Leu-Phe-OH; L-asparagyl-L-seryl-L-lysyl-L-methionyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-L-glutaminyl-L-lysyl-L-isoleucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-seryl-L-arginyl-L-leucyl-glycyl-L-cysteinyl-L-alpha-aspartyl-glycyl-L-leucyl-L-arginyl-L-leucyl-L-phenylalanine (10->26)-disulfide. Grade: 95%. CAS No. 133448-20-1. Molecular formula: C146H239N47O44S3. Mole weight: 3452.94.
Brain Natriuretic Peptide (BNP) (1-32), rat TFA
Brain Natriuretic Peptide (BNP) (1-32), rat TFA is a 32-amino acid polypeptide secreted by the ventricle in response to overstretching of cardiomyocytes. Synonyms: Brain Natriuretic Peptide-32 (rat) TFA; BNP (1-32), rat TFA; H-Asn-Ser-Lys-Met-Ala-His-Ser-Ser-Ser-Cys(1)-Phe-Gly-Gln-Lys-Ile-Asp-Arg-Ile-Gly-Ala-Val-Ser-Arg-Leu-Gly-Cys(1)-Asp-Gly-Leu-Arg-Leu-Phe-OH.TFA; L-asparagyl-L-seryl-L-lysyl-L-methionyl-L-alanyl-L-histidyl-L-seryl-L-seryl-L-seryl-L-cysteinyl-L-phenylalanyl-glycyl-L-glutaminyl-L-lysyl-L-isoleucyl-L-alpha-aspartyl-L-arginyl-L-isoleucyl-glycyl-L-alanyl-L-valyl-L-seryl-L-arginyl-L-leucyl-glycyl-L-cysteinyl-L-alpha-aspartyl-glycyl-L-leucyl-L-arginyl-L-leucyl-L-phenylalanine (10->26)-disulfide trifluoroacetic acid. Grade: >98%. Molecular formula: C146H239N47O44S3.C2HF3O2. Mole weight: 3566.96.
Branaplam
Branaplam (LMI070; NVS-SM1) is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LMI070; NVS-SM1. CAS No. 1562338-42-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg. Product ID: HY-19620.
Branaplam (LMI070; NVS-SM1) hydrochloride is a highly potent, selective and orally active survival motor neuron-2 (SMN2) splicing modulator with an EC50 of 20 nM for SMN. Branaplam hydrochloride inhibits human-ether-a-go-go-related gene (hERG) with an IC50 of 6.3 μM. Branaplam hydrochloride elevates full-length SMN protein and extends survival in a severe spinal muscular atrophy (SMA) mouse model[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LMI070 hydrochloride; NVS-SM1 hydrochloride. CAS No. 1562338-39-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19620A.
branched-chain-2-oxoacid decarboxylase
Acts on a number of 2-oxo acids, with a high affinity towards branched-chain substrates. The aldehyde formed may be enzyme-bound, and may be an intermediate in the bacterial system for the biosynthesis of branched-chain fatty acids. Group: Enzymes. Synonyms: branched-chain oxo acid decarboxylase; branched-chain α-keto acid decarboxylase; branched-chain keto acid decarboxylase; BCKA; (3S)-3-methyl-2-oxopentanoate carboxy-lyase. Enzyme Commission Number: EC 4.1.1.72. CAS No. 63653-19-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4820; branched-chain-2-oxoacid decarboxylase; EC 4.1.1.72; 63653-19-0; branched-chain oxo acid decarboxylase; branched-chain α-keto acid decarboxylase; branched-chain keto acid decarboxylase; BCKA; (3S)-3-methyl-2-oxopentanoate carboxy-lyase. Cat No: EXWM-4820.
Also acts on L-isoleucine and L-valine, and thereby differs from EC 2.6.1.6, leucine transaminase, which does not. It also differs from EC 2.6.1.66, valine-pyruvate transaminase. Group: Enzymes. Synonyms: transaminase B; branched-chain amino acid aminotransferase; branched-chain amino acid-glutamate transaminase; branched-chain aminotransferase; L-branched chain amino acid aminotransferase; glutamate-branched-chain amino acid transaminase. Enzyme Commission Number: EC 2.6.1.42. CAS No. 9054-65-3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2883; branched-chain-amino-acid transaminase; EC 2.6.1.42; 9054-65-3; transaminase B; branched-chain amino acid aminotransferase; branched-chain amino acid-glutamate transaminase; branched-chain aminotransferase; L-branched chain amino acid aminotransferase; glutamate-branched-chain amino acid transaminase. Cat No: EXWM-2883.
branched-chain-fatty-acid kinase
3-Methylbutanoate, 2-methylbutanoate, pentanoate, butanoate and propanoate can also act as acceptors (cf. EC 2.7.2.7 butyrate kinase). Group: Enzymes. Synonyms: isobutyrate kinase. Enzyme Commission Number: EC 2.7.2.14. CAS No. 84177-54-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3172; branched-chain-fatty-acid kinase; EC 2.7.2.14; 84177-54-8; isobutyrate kinase. Cat No: EXWM-3172.
branched-dextran exo-1,2-α-glucosidase
Does not hydrolyse disaccharides or oligosaccharides containing linear 1,2-α-glucosidic linkages.
branched-dextran exo-1,2-α-glucosidase
Does not hydrolyse disaccharides or oligosaccharides containing linear 1,2-α-glucosidic linkages. Group: Enzymes. Synonyms: dextran 1,2-α-glucosidase; dextran α-1,2 debranching enzymel 1,2-α-D-glucosyl-branched-dextran 2-glucohydrolase. Enzyme Commission Number: EC 3.2.1.115. CAS No. 72840-94-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3798; branched-dextran exo-1,2-α-glucosidase; EC 3.2.1.115; 72840-94-9; dextran 1,2-α-glucosidase; dextran α-1,2 debranching enzymel 1,2-α-D-glucosyl-branched-dextran 2-glucohydrolase. Cat No: EXWM-3798.
Branched PEI-g-PEG
PEI-g-PEG is a graft copolymer of branched PEI (bPEI), which is modified with multiple PEGs of indicated MW. The PEG to PEI ratio is the average number of PEGs per PEI. Alternative Names: PEI-PEG, Branched polyethylenimine-graft-poly(ethylene glycol), PEI-g-PEG. Molecular formula: H3CO[(CH2)2O]nC12H23N3O3[NH(CH2)2]mNH2. Mole weight: PEG Mn 550.
Brandioside
Brandioside. Group: Biochemicals. CAS No. 133393-81-4. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Branebrutinib
Branebrutinib (BMS-986195) is a highly potent, selective covalent, irreversible inhibitor of Brutons tyrosine kinase (BTK), with an IC50 of 0.1 nM[1][2]. Branebrutinib is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BMS-986195. CAS No. 1912445-55-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112161.
Br-ANT-ATP
Br-ANT-ATP is an analogue of adenosine-5'-triphosphate, of which the intrinsic fluorescence would increase in hydrophobic environment. It can be used for research into ATP-dependent receptor proteins. Synonyms: 2'- / 3'- O- (5- Bromoanthraniloyl)adenosine- 5'- O- triphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 1350521-49-1. Molecular formula: C17H20BrN6O14P3 (free acid). Mole weight: 705.2 (free acid).
Brasilicardin A
Brasilicardin A is a tricyclic diterpene antibiotic produced by Nocardia brasiliensis IFM 0406. It has no antibacterial activity and has an immunosuppressive effect. Molecular formula: C45H68N2O16. Mole weight: 893.02.
Brasilinolide A
Brasilinolide A is a lactone produced by Nocardia brasiliensis. Synonyms: Propanedioic acid, mono(14-(6-((2,6-dideoxy-3-O-(1-oxopentyl)-beta-D-lyxo-hexopyranosyl)oxy)-2,4-dihydroxy-1,3,5-trimethylheptyl)-3,9,20,22,24,28,30,31,32-nonahydroxy-13,27-dimethyl-16-oxo-11,15,34-trioxatricyclo(28.3.1.0(sup 10,12))tetratriacont-17-en-5-yl) ester; 3-[[2,4-dihydroxy-6-(5-hydroxy-6-methyl-4-pentanoyloxy-tetrahydropyran-2-yl)oxy-1,3,5-trimethyl-heptyl]-nonahydroxy-dimethyl-oxo-[?]yl]oxy-3-oxo-propanoic acid. CAS No. 179041-27-1. Molecular formula: C57H98O24. Mole weight: 1167.37.
Brasilinolide B
Brasilinolide B is a lactone produced by Nocardia brasiliensis. Synonyms: (1R,3R,5R,9S,10S,12S,13R,14R,17E,20S,22R,24S,27R,28R,30S,31R,32S)-14-{(2S,3S,4R,5R,6R,7S)-7-[(2,6-dideoxy-3,4-di-O-methyl-alpha-L-lyxo-hexopyranosyl)oxy]-3,5-dihydroxy-4,6-dimethyloctan-2-yl}-3,9,20,22,24,28,30,31,32-nonahydroxy-13,27-dimethyl-16-oxo-11,15,34-trioxatricyclo[28.3.1.0(10,12)]tetratriacont-17-en-5-yl methyl butylpropanedioate. CAS No. 262596-89-4. Molecular formula: C59H104O23. Mole weight: 1181.44.
Brasiliquinone A
Brasiliquinone A is a benzo-onionquinone antibiotic produced by Nocardia brasiliensis, which has anti-gram-positive bacteria and tumor activity. Synonyms: (3S)-3-ethyl-6-hydroxy-1,7,12-trioxo-1,2,3,4,7,12-hexahydrotetraphen-8-yl 3-amino-2,3,6-trideoxy-alpha-L-ribo-hexopyranoside. CAS No. 183201-02-7. Molecular formula: C26H27NO7. Mole weight: 465.49.
Brasiliquinone B
Brasiliquinone B is a benzo-onionquinone antibiotic produced by Nocardia brasiliensis, which has anti-gram-positive bacteria and tumor activity. Synonyms: (3S)-3-ethyl-6,8-dihydroxy-3,4-dihydrotetraphene-1,7,12(2H)-trione. CAS No. 183201-04-9. Molecular formula: C20H16O5. Mole weight: 336.34.
Brasiliquinone C
Brasiliquinone C is a benzo-onionquinone antibiotic produced by Nocardia brasiliensis, which has anti-gram-positive bacteria and tumor activity. Synonyms: (3S)-3-ethyl-6-hydroxy-8-methoxy-3,4-dihydrotetraphene-1,7,12(2H)-trione. CAS No. 183201-06-1. Molecular formula: C21H18O5. Mole weight: 350.36.
Brasiliquinone D
Brasiliquinone D is a benzo-onionquinone antibiotic produced by Nocardia brasiliensis. Molecular formula: C28H29NO8. Mole weight: 507.53.
Brasofensine
Brasofensine is a phenyltropane drug that is developed for the treatment of Parkinson's and Alzheimer's disease. Synonyms: NS-2214; BMS-204756; (E)-1-[(2R,3S)-3-(3,4-dichlorophenyl)-8-methyl-8-azabicyclo[3.2.1]octan-2-yl]-N-methoxymethanimine. CAS No. 171655-91-7. Molecular formula: C16H20Cl2N2O. Mole weight: 327.249.