A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Butyrolactone i. Uses: Designed for use in research and industrial production. Additional or Alternative Names: BUTYROLACTONE I;2,5-Dihydro-4-hydroxy-2-[4-hydroxy-3-(3-methyl-2-butenyl)benzyl]-3-(4-hydroxyphenyl)-5-oxofuran-2-carboxylic acid methyl ester. Product Category: Heterocyclic Organic Compound. Appearance: white solid. CAS No. 87414-49-1. Molecular formula: C24H24O7. Mole weight: 424.44. Product ID: ACM87414491. Alfa Chemistry ISO 9001:2015 Certified.
Butyrolactone I
It is one of a family of three butyrolactones isolated from aspergillus fumigatus. It exhibits antitumor activity and inhibits the cell cycle at the G1/S and G2/M transitions. It is a selective inhibitor of cyclin-dependent kinases CDK1/cyclin B, CDK2 and CDK5. Synonyms: Olomoucin; 4'-O-Demethylversicolactone D; (2R)-2,5-Dihydro-4-hydroxy-2-[[4-hydroxy-3-(3-methyl-2-butenyl)phenyl]methyl]-3-(4-hydroxyphenyl)-5-oxo-2-furancarboxylic Acid Methyl Ester; (+)-3''-Dimethylallyl-butyrolactone II. Grades: >95% by HPLC. CAS No. 87414-49-1. Molecular formula: C24H24O7. Mole weight: 424.44.
Butyrolactone I
Butyrolactone I is an exogenous inhibitor of CDK cyclin-dependent kinases. Group: Biochemicals. Grades: Highly Purified. CAS No. 87414-49-1. Pack Sizes: 200ug, 400ug. Molecular Formula: C24H24O7, Molecular Weight: 424.44. US Biological Life Sciences.
Worldwide
Butyrolactone I - CAS 87414-49-1
A cell-permeable and highly selective inhibitor of cyclin-dependent protein kinases (Cdks) that inhibits cell cycle progression at the G?/S and G?/M transitions. Group: Fluorescence/luminescence spectroscopy.
Butyrolactone I - CAS 87414-49-1
Fluorescence/Luminescence Spectroscopy. Uses: For analytical and research use. Group: Reagents. CAS No. 87414-49-1. Pack Sizes: 200UG.
Butyrolactone II
Butyrolactone II is an antibiotic and it is weak cytotoxic towards bacterial and cancer cell lines. It is also a 5-Lipoxygenase (5-LOX) inhibitor and has shown DPPH (2,2-diphenyl-1-picrylhydrazyl) radical-scavening activity. Synonyms: (2R)-2,5-Dihydro-4-hydroxy-3-(4-hydroxyphenyl)-2-[(4-hydroxyphenyl)methyl]-5-oxo-2-furancarboxylic Acid Methyl Ester. Grades: >95%. CAS No. 87414-44-6. Molecular formula: C19H16O7. Mole weight: 356.33.
Butyrolactone II
Butyrolactone II is an antibiotic, a 5-LOX inhibitor and has shown DPPH radical-scavening activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 87414-44-6. Pack Sizes: 500ug, 1000ug. Molecular Formula: C19H16O7, Molecular Weight: 356.33. US Biological Life Sciences.
Worldwide
Butyrolactone V
Butyrolactone V is a fungal metabolite that is produced by A. terreus and it has antiprotozoal, antioxidant, and anticancer activities. It is active against the P. falciparum strain K1 (IC50 = 7.9 μg/ml) and L. amazonensis promastigotes (IC50 = 23.7 μM). Butyrolactone V also inhibits proliferation of MDA-MB-231 and MCF-7 breast cancer cells (IC50s = 22.2 and 31.9 μM, respectively). Synonyms: (2R)-2-[[(3S)-3,4-dihydro-3-hydroxy-2,2-dimethyl-2H-1-benzopyran-6-yl]methyl]-2,5-dihydro-4-hydroxy-3-(4-hydroxyphenyl)-5-oxo-2-Furancarboxylic acid, methyl ester. Grades: >95% by HPLC. CAS No. 1151509-01-1. Molecular formula: C24H24O8. Mole weight: 440.44.
Butyronitrile
Butyronitrile. CAS No: 109-74-0
Sarchem Laboratories New Jersey NJ
Butyronitrile diethyl malonate
Butyronitrile diethyl malonate. Group: Biochemicals. Alternative Names: Diethyl-3-cyanopropylmalonate; 2- (3-Cyanopropyl) propanedioic acid 1,3-diethyl ester. Grades: Highly Purified. CAS No. 63972-18-9. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C11H17NO4. US Biological Life Sciences.
Butyronitrile Diethyl Malonate (Diethyl-3-cyanopropylmalonate). Group: Biochemicals. Alternative Names: Diethyl-3-cyanopropylmalonate. Grades: Highly Purified. Pack Sizes: 2.5g. US Biological Life Sciences.
Worldwide
Butyrophenone
Butyrophenone is used as an antipsychotic drug in pharmacotherapy. Group: Biochemicals. Alternative Names: 1-Phenyl-1-butanone; 1-Benzoylpropane; 1-Phenyl-1-butanone; Butanophenone; NSC 8463; Phenyl n-Propyl Ketone; Phenyl Propyl Ketone; Propyl Phenyl Ketone; n-Butyrophenone; n-Propyl Phenyl Ketone. Grades: Highly Purified. CAS No. 495-40-9. Pack Sizes: 5g. US Biological Life Sciences.
Worldwide
Butyrophenone
analytical standard. Group: Flavor and fragrance standards.
Butyrospermum Parkii (Shea Butter)
Sheatree, Butyrospermum parkii, also known as Vitellaria paradoxa, is the source of Butyrospermum Parkii (Shea) Butter. When raw, it is ivory in colour and is frequently coloured yellow with palm oil or borutu root. It is used in numerous cosmetic and personal care products, such as bath and cleaning products, eye makeup, lotions and creams, suntan products, lipstick, and hair care products, where it functions as emollients and viscosity controllers. Uses: 1. moisturizer - shea butter is a natural emollient that helps to lock in moisture and improve skin hydration. it is easily absorbed into the skin and does not leave a residue. 2. anti-inflammatory - shea butter contains cinnamic acid, which has been shown to have anti-inflammatory properties. this makes it helpful in treating inflammatory skin conditions like acne, eczema, and psoriasis. 3. anti-. Additional or Alternative Names: BUTYROSPERMUM PARKII (SHEA BUTTER);Fats and Glyceridic oils, shea butter;BUTYROSPERMUM PARKII (SHEA BUTTER LIQUID);SHEA BUTTER BUTYROSPERMUM PARKII. Product Category: Heterocyclic Organic Compound. CAS No. 194043-92-0. Product ID: ACM194043920. Alfa Chemistry ISO 9001:2015 Certified.
Butyrylcarnitine
Butyrylcarnitine is a metabolite in plasma, acts as a biomarker to improve the diagnosis and prognosis of heart failure, and is indicative of anomalous lipid and energy metabolism. Uses: Scientific research. Group: Natural products. CAS No. 25576-40-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-113168.
25g Pack Size. Group: Building Blocks, Organics. Formula: C9H20ClNO2. CAS No. 2963-78-2. Prepack ID 49629139-25g. Molecular Weight 209.71. See USA prepack pricing.
Butyrylcholine chloride
Butyrylcholine (chloride) is a biochemical assay reagent. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2963-78-2. Pack Sizes: 50 mg. Product ID: HY-W014419.
Butyrylcholine Chloride
Butyrylcholine Chloride. Group: Biochemicals. Grades: Highly Purified. CAS No. 2963-78-2. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences.
Worldwide
Butyrylcholine iodide
Butyrylcholine Iodide is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 2494-56-6. Pack Sizes: 100 mg. Product ID: HY-W009236.
Butyrylcholine perchlorate
Butyrylcholine perchlorate, a potent biomedical compound, finds its application in both research and clinical environments. Serving as an acetylcholine receptor agonist, this cholinergic substance bravely delves into unraveling the intricate mechanisms governing cholinergic neurotransmission. With an unwavering dedication to scientific exploration, it illuminates the enigmatic role played by this neurotransmission in afflictions such as Alzheimer's disease, myasthenia gravis, and an array of formidable neuromuscular disorders. Synonyms: BUTYRYLCHOLINE PERCHLORATE; Trimethyl(2-(1-oxobutoxy)ethyl)ammonium perchlorate; EINECS 243-700-3; 2-butanoyloxyethyl(trimethyl)azanium; perchlorate; 566ZY7YY3K; DTXSID80174172; [2-(butanoyloxy)ethyl]trimethylazanium perchlorate; Ethanaminium, N,N,N-trimethyl-2-(1-oxobutoxy)-, perchlorate; Ethanaminium, N,N,N-trimethyl-2-(1-oxobutoxy)-, perchlorate (1:1). CAS No. 20292-68-6. Molecular formula: C9H20ClNO6. Mole weight: 273.71.
Butyrylcholinesterase (BCHE), Horse Serum
Butyrylcholinesterase (BCHE), Horse Serum (BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acyl-hydrolase, Choline esterase, butyryl) is a biological material or organic compound that can be used in life science research[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BCHE, BuChE, PCHE, pseudocholinesterase, plasma cholinesterase, Acylcholine acyl-hydrolase, Choline esterase, butyryl. Pack Sizes: 200 U; 500 U. Product ID: HY-E70362.
Butyryl-Coenzyme A lithium hydrate
Butyryl-Coenzyme A lithium hydrate can synthesize Butyric acid (HY-B0350) or Butyrate [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Butyryl CoA lithium hydrate. CAS No. 1107039-35-9. Pack Sizes: 500 μg; 1 mg. Product ID: HY-141479B.
(R)-Butyryl Carnitine is a potential prodrug of Carnitine, via the carnitine transporter OCTN2 and the amino acid transporter ATB0,+. It is an inhibitor of intestinal transporters, which block carnitine uptake by the carnitine transporter with IC50s of 1.5 μM and glycine transport with IC50s of 4.6 μM in in human retinal pigment epithelial (HRPE) cells. Butyryl-L-carnitine is used for treating seizure disorders. Synonyms: L-Butyrylcarnitine; C4 Carnitine. Grades: ≥95%. CAS No. 162067-50-7. Molecular formula: C11H22NO4·Cl. Mole weight: 267.8.
Butyryl-L-carnitine chloride 98+% (TLC)
Butyryl-L-carnitine chloride 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 25mg, 100mg, 250mg. US Biological Life Sciences.
Worldwide
Butyryl-L-carnitine-d3 chloride
Butyryl-L-carnitine-d 3 (chloride) is the deuterium labeled Butyryl-L-carnitine chloride[1]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1334532-21-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-115704S1.
Butyryl Phosphate Dilithium Salt
Butyryl phosphate has a role in metabolism. Group: Biochemicals. Alternative Names: Butanoic Acid Phosphono Ester Dilithium Salt; Butanoyl Phosphate Dilithium Salt. Grades: Highly Purified. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
Butyrylthiocholine chloride
1g Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Diagnostic Raw Materials, Organics. Formula: C9H20ClNOS. CAS No. 22026-63-7. Prepack ID 26608039-1g. Molecular Weight 225.78. See USA prepack pricing.
Butyrylthiocholine iodide
5g Pack Size. Group: Building Blocks, Organics. Formula: C9H20INOS. CAS No. 1866-16-6. Prepack ID 34904481-5g. Molecular Weight 317.23. See USA prepack pricing.
Butyzamide
Butyzamide is an orally active activator of Mpl, a thrombopoietin (TPO) receptor. Butyzamide increases the phosphorylation level of JAK2, STAT3, STAT5 and MAPK. Butyzamide increases the level of human platelets in mouse xenotransplantation assay[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1110767-45-7. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148748.
Buxtamine (Buxtauine, Cyclobuxoxine)
Buxtamine (Buxtauine, Cyclobuxoxine). Group: Biochemicals. Alternative Names: Buxtauine M; Cyclomicrobuxinine; Cyclobuxoxine. Grades: Plant Grade. CAS No. 4236-73-1. Pack Sizes: 10mg. Molecular Formula: C24H37NO2, Molecular Weight: 371.555999999999. US Biological Life Sciences.
Worldwide
Buxtauine
Buxtauine. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Buxtauine. Product Category: Heterocyclic Organic Compound. CAS No. 4236-73-1. Molecular formula: C24H37NO2. Mole weight: 371.56. Product ID: ACM4236731. Alfa Chemistry ISO 9001:2015 Certified. Categories: Buxtamine.
BV02
BV02 is a 14-3-3 inhibitor and an antibacterial agent. BV02 enhances the cleavage of PARP and caspase-3. BV02 induces Apoptosis, Autophagy, and enhances Akt activation. BV02 has anti-B. melitensis infection and epilepsy-promoting effects. BV02 can also be used in colitis research. Uses: Scientific research. Group: Signaling pathways. CAS No. 292870-53-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101985.
BV6 is an antagonist of cIAP1 and XIAP, members of the inhibitors of apoptosis (IAP) family. Uses: Scientific research. Group: Signaling pathways. CAS No. 1001600-56-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16701.
BV6
BV-6 is a selective inhibitor of apoptosis (IAP) family with IC50 value of 7.2 μM when tested with H460 cells. It acts by promoting glioblastoma cancer stem-like cell differentiation by activating NF-κB. BV-6 induces autoubiquitination and proteasomal degradation of IAP1 and XIAP in MDA-MB-231 cells at 5 μM. In BALB/c mice model with transplanted abdominal cavities from donor mouse uterine tissue, intraperitoneally with BV-6 repressed the advancement of endometriosis, cell proliferative activity via inhibiting the expression of IAPs. In hematological THP-1 cells, pre-treatment with BV-6 increased the CIK cells killing ability and the same results were achieved in solid malignancy RH30 cells. Grades: ≥98%. CAS No. 1001600-56-1. Molecular formula: C70H96N10O8. Mole weight: 1205.57.
Bvacado Oil microencapsulated powder
Bvacado Oil microencapsulated powder. Product ID: CDF4-0212. Molecular formula: NA. Category: Nutrient supplements. Product Keywords: Food Ingredients; Nutrients; CDF4-0212; Bvacado Oil microencapsulated powder; Nutrient supplements. Appearance: White to light yellow powder. Color: White to light yellow. Physical State: powder. Source and Preparation: Bvacado. Applications: Dietary supplements, nutritional supplements, cosmetic raw materials, etc.
BVD 10
BVD 10 is a selective NPY Y1 receptor antagonist (Ki = 25.7, 1420, 2403 and 7100 nM at Y1, Y2, Y4 and Y5 receptors, respectively) with no activity at Y4 receptors. Synonyms: BVD 10; BVD10; BVD-10. Grades: >98%. CAS No. 262418-00-8. Molecular formula: C58H92N16O13. Mole weight: 1221.46.
BVFP
BVFP binds to the PGRN 588 - 593 peptide with a K d of 20 μM. BVFP can disrupt PGRN-SORT1 binding. BVFP also inhibits SORT1-mediated rPGRN endocytosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 357158-20-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 1100 mg. Product ID: HY-153686.
BVT-14225 is a highly selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor(IC50 = 52 nM), which is 1,000 fold lower than that for 11β-HSD2. Synonyms: 2-[2-[(3-chloro-2-methylphenyl)sulfonylamino]-1,3-thiazol-4-yl]-N,N-diethylacetamide; BVT-14225; BVT 14225; BVT14225. CAS No. 376638-65-2. Molecular formula: C16H20ClN3O3S2. Mole weight: 401.93.
BVT 2733
BVT 2733 is a non-steroidal small molecule as a selective 11β-hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor (IC = 96 ± 14 nM). Synonyms: BVT-2733; BVT 2733; BVT2733; 3-chloro-2-methyl-N-(4-(2-(4-methylpiperazin-1-yl)-2-oxoethyl)thiazol-2-yl)benzenesulfonamide; Piperazine, 1-((2-(((3-chloro-2-methylphenyl)sulfonyl)amino)-4-thiazolyl)acetyl)-4-methyl-. Grades: 98%. CAS No. 376640-41-4. Molecular formula: C17H21ClN4O3S2. Mole weight: 428.95.
BVT 2733 hydrochloride is a selective inhibitor of 11β-hydroxysteroid dehydrogenase type 1. Synonyms: BVT 2733 hydrochloride; BVT2733 hydrochloride; BVT-2733 hydrochloride; 3-chloro-2-methyl-N-[4-[2-(4-methylpiperazin-1-yl)-2-oxoethyl]-1,3-thiazol-2-yl]benzenesulfonamide hydrochloride. Grades: 99%. CAS No. 376641-65-5. Molecular formula: C17H21ClN4O3S2.HCl. Mole weight: 465.42.
BVT948
BVT948 is a protein tyrosine phosphatase (PTP) inhibitor which can also inhibit several cytochrome P450 (P450) isoforms and lysine methyltransferase SETD8 (KMT5A). Uses: Scientific research. Group: Signaling pathways. CAS No. 39674-97-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100625.
BVT 948
BVT 948. Group: Biochemicals. Grades: Purified. CAS No. 39674-97-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BVT-948
BVT 948 is a non-competitive and cell-permeable inhibitor of protein tyrosine phosphatases (PTPs) (IC50 = 0.09 - 1.7 μM). BVT 948 displays irreversible inhibition through catalysis of the hydrogen peroxide-dependent oxidation of PTP, and enhances insulin signaling in vitro and insulin tolerance in ob/ob mice in vivo. Some cytochrome P450 isoforms are also suppressed by BVT 948 (IC50 <10 μM). Synonyms: BVT948; BVT-948; BVT 948; SPS8I3; SPS-8I3; SPS 8I3; 4-Hydroxy-3,3-dimethyl-2H-benz[g]indole-2,5(3H)-dione. Grades: ≥98% by HPLC. CAS No. 39674-97-0. Molecular formula: C14H11NO3. Mole weight: 241.24.
BW 245C, a prostaglandin analogue, is a selective prostanoid DP-receptor (DP1) agonist used to treat stroke where the Ki for the inhibition of [3H]-PGD2 binding to isolated human platelet membranes is 0.9 nM and has a reported IC50 of 2.5 nM for the inhibition of ADP-induced human platelet aggregation. Synonyms: 7-[(4S)-3-[(3R)-3-cyclohexyl-3-hydroxypropyl]-2,5-dioxoimidazolidin-4-yl]heptanoic acid; 245C77; 5-(6-carboxyhexyl)-1-(3-cyclohexyl-3-hydroxypropyl)hydantoin; BW 245C; BW 245C, (R*,S*)-(+-); BW-245C. CAS No. 72814-32-5. Molecular formula: C19H32N2O5. Mole weight: 368.47.
BW 246C
The prostaglandin D2 (PGD2) receptors are the members of G protein-coupled receptors. PGD2 receptors include the following proteins prostaglandin D2 receptor 1 (DP1) and prostaglandin D2 receptor 2 (DP2). BW 246C is a DP receptor agonist. BW 246C is the less active C-8 diastereomer of the DP receptor agonist BW 245C. The activity of BW 245C is 70-fold greater than that of BW 246C. Synonyms: 8-epi BW 245C. Grades: ≥98%. CAS No. 65705-83-1. Molecular formula: C19H32N2O5. Mole weight: 368.5.
BW 373U86
BW 373U86 is a potent and selective non-peptide δ-opioid receptor agonist (Ki = 1.8, 15 and 34 nM for δ, μ and κ receptors, respectively). Synonyms: BW-373U86; SNC-86; BW 373U86; SNC 86; BW373U86; SNC86; 4-[(αR)-α-((2S,5R)-4-Allyl-2,5-dimethyl-1-piperazinyl)-3-hydroxybenzyl]-N,N-diethylbenzamide. Grades: ≥99% by HPLC. CAS No. 155836-50-3. Molecular formula: C27H37N3O2. Mole weight: 435.61.
BW-723C86 is an orally active and a selective 5-HT 2B receptor agonist. BW-723C86 exhibits anxiolytic-like actions. BW-723C86 also causes hyperphagia and reduced grooming in rats. BW-723C86 dilates pulmonary arteries and inhibits liquid meal-induced gastric accommodation [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. CAS No. 160521-72-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101369.
BW 723C86 hydrochloride
BW 723C86 hydrochloride is a selective 5-HT2B receptor agonist used for the treatment of certain CNS disorders, such as epilepsy, migraine and feeding disorders. Uses: The treatment of cns disorders as epilepsy, migraine and feeding disorders. Synonyms: BW723C86; BW-723-C-86; BW 723 C 86; BW-723C86; BW 723C86; α-methyl-5-(2-thienylmethoxy)-1H-indole-3-ethanamine hydrochloride. Grades: ≥99% by HPLC. CAS No. 160521-72-2. Molecular formula: C16H18N2OS.HCl. Mole weight: 322.85.
BW 723C86 hydrochloride
BW 723C86 hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 160521-72-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BW 755C
Constitutive cyclooxygenase (COX-1) is present in cells under physiological conditions, whereas COX-2 is induced by some cytokines, mitogens, and endotoxin in pathological conditions, such as inflammation. Since 5-lipoxygenase (5-LO) oxidizes arachidonic acid to 5-hydroperoxyeicosatetraenoic acid. BW 755C is a dual inhibitor of 5-lipoxygenase (5-LO) and cyclooxygenase (COX) pathways. It inhibits 5-LO with IC50s of 0.75 μM, COX-1 with IC50s of 0.65 μg/ml, and COX-2 with IC50s of 1.2 μg/ml. BW 755C may also inhibit other LO pathways in vivo. Uses: Anti-inflammatory agents, non-steroidal. Synonyms: BW755C; BW-755C; 1H-Pyrazol-3-amine, 4,5-dihydro-1-[3-(trifluoromethyl)phenyl]-; 4,5-Dihydro-1-[3-(trifluoromethyl)phenyl]-1H-pyrazol-3-amine; 1-(3-Trifluoromethylphenyl)-4,5-dihydro-1H-pyrazol-3-amine; 3-Amino-1-[3-(trifluoromethyl)phenyl]-2-pyrazoline; 3-Amino-1-[3-(trifluoromethyl)phenyl]pyrazoline; 3-Amino-1-[m-(trifluoromethyl)phenyl]-2-pyrazoline; Compound BW 755C. Grades: ≥95%. CAS No. 66000-40-6. Molecular formula: C10H10F3N3. Mole weight: 229.20.
BWA-522 is an orally available small molecule protein-targeting chimera (PROTACs) with significant degradation effect on AR-FL and AR-V7. BWA-522 antagonizes the N-terminal domain (AR-NTD) of the androgen receptor (Androgen Receptor) and induces apoptosis in PC cells. BWA-522 inhibits tumor growth in LNCaP xenograft model studies (60 mg/kg, po; TGI=76%). The efficiencies of BWA-522 in degrading AR-V7 and AR-FL were 77.3% (1 ?M) and 72.0% (5 ?M) in VCaP and LNCaP cells, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3042820-12-9. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-149433.
BW-A78U
BW-A 78U is a PDE4 inhibitor with an IC50 of 3 μM. BW-A 78U fails to significantly inhibit arachidonate release. It is ineffective to inhibit the lipopolysaccharide (LPS)-induced TNF-α release. Synonyms: BW A78U. Grades: ≥98%. CAS No. 101155-02-6. Molecular formula: C13H12FN5. Mole weight: 257.27.
BW A868C
Prostaglandin D2 (PGD2) has been widely distributed in rat brain, spinal cord and pituitary and may act as a neuromodulator in the central nervous system. BW A868C is a novel, selective and potent competitive antagonist of PGD2. BW A868C antagonizes the prostaglandin D2 and BW 245C-induced activation of human platelet adenylate cyclase. BW A868C antagonizes the accumulation of cAMP in rabbit non-pigmented ciliary epithelial cells. However, it has virtually no effect on human TP, IP, EP1, EP2, and FP receptors. Synonyms: BWA-868C; BWA868C. Grades: ≥98%. CAS No. 118675-50-6. Molecular formula: C25H37N3O5. Mole weight: 459.6.
BW-B 70C. Group: Biochemicals. Grades: Purified. CAS No. 134470-38-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
BW-B 70C
BW B70C is a potent and selective inhibitor of 5-lipoxygenase (5-LO). 5-LO is an enzyme that transforms essential fatty acids (EFAs) into leukotrienes and is activated by 5-lipoxygenase activating protein (FLAP). BW-B 70C had high potency and long duration in vivo and was considered as potential anti-asthma drug. It was reported that BW B70C blocks leukotriene C4 synthesis by alveolar macrophages, which decreases the migration for leukocyte to the airway lumen. BW B70C didn't affect vascular leucocyte margination and the blood levels of secreted phospholipase A2 and TNF-&alpha. Synonyms: N-[3-[3-(-Fluorophenoxy)phenyl]-1-methyl-2-propenyl]-N-hydroxyurea. Grades: ≥98%. CAS No. 134470-38-5. Molecular formula: C17H17FN2O3. Mole weight: 316.33.
BWX 46
BWX 46. Group: Biochemicals. Grades: Purified. CAS No. 172997-92-1. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
BX-320
BX-320 is a selective, ATP-competitive, orally acitive, and direct PDK1 inhibitor with an IC 50 of 30 nM in a direct kinase assay format. BX-320 also induces apoptosis. Anticancer effect [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 702676-93-5. Pack Sizes: 1 mg. Product ID: HY-10515.