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| Product | Description | |
|---|---|---|
| BRD73954 | BRD73954 ia a potent and selective HDAC inhibitor with IC50 of 36 nM and 120 nM for HDAC6 and HDAC8, respectively. Synonyms: BRD73954; BRD-73954; BRD 73954. Grade: >98%. CAS No. 1440209-96-0. Molecular formula: C16H16N2O3. Mole weight: 284.31. |  |
| BRD7552 | BRD7552, a potent PDX1 transcription factor inducer, upregulates PDX1 expression in both primary human islets and ductal cells, and induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. BRD7552 increases insulin expression. PDX1 is a key transcription factor involved in pancreas development and β cell function[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1137359-47-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg. Product ID: HY-19694. |  |
| BRD7552 | BRD7552 is an inducer of transcription factor PDX1, which increases insulin expression. Synonyms: BRD-7552; BRD 7552; BRD7552. Grade: 95%. CAS No. 1137359-47-7. Molecular formula: C33H33N3O15. Mole weight: 711.63. | |
| BRD 7552 | PDX1 transcription factor inducer; up regulates PDX1 expression in both primary human islets and ductal cells. Induces epigenetic changes in the PDX1 promoter consistent with transcriptional activation. Increases insulin expression in PANC-1 cells, primary human islets and human duct-derived cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 1137359-47-7. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| BRD7-IN-1 | BRD7-IN-1 is a modified derivative of BI7273 (BRD7/9 inhibitor) and binds to a VHL ligand via a linker to form a PROTAC VZ185. Synonyms: 4-[3,5-Dimethoxy-4-(1-piperazinylmethyl)phenyl]-2-methyl-2,7-naphthyridin-1(2H)-one dihydrochloride; 2,7-Naphthyridin-1(2H)-one, 4-[3,5-dimethoxy-4-(1-piperazinylmethyl)phenyl]-2-methyl-, hydrochloride (1:2). Grade: ≥95%. CAS No. 2448414-48-8. Molecular formula: C22H28Cl2N4O3. Mole weight: 467.39. | |
| BRD7-IN-1 | BRD7-IN-1, a modified derivative of BI7273 (BRD7/9 inhibitor), binds to a VHL ligand via a linker to form a PROTAC VZ185 (VZ185 against BRD7/9 with DC50s of 4.5 and 1.8 nM, respectively)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2448414-48-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111905. | |
| BRD7-IN-1 free base | BRD7-IN-1 free base is a modified derivative of BI7273 (BRD7/9 inhibitor) that binds to a VHL ligand via a linker to form a PROTAC VZ185. Synonyms: 2,7-Naphthyridin-1(2H)-one, 4-[3,5-dimethoxy-4-(1-piperazinylmethyl)phenyl]-2-methyl-; 4-[3,5-Dimethoxy-4-(1-piperazinylmethyl)phenyl]-2-methyl-2,7-naphthyridin-1(2H)-one. Grade: ≥95%. CAS No. 2305379-66-0. Molecular formula: C22H26N4O3. Mole weight: 394.47. | |
| BRD7-IN-2 | BRD7-IN-2 (compound 2-77) is a potent inhibitor of bromodomain-containing protein 7 (BRD7), targeting to prostate cancer cells. BRD7-IN-2 is selective for BRD7 rather than BRD9, with IC50s of 5.4 μM, and >300 μM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032601-06-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149420. | |
| BRD-8000.3 | BRD-8000.3, as a specific EfpA inhibitor, is a narrow-spectrum, bactericidal antimycobacterial agent with good wild-type activity. BRD-8000.3 can be used for the research of tuberculosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2365504-95-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141715. | |
| BRD-810 | BRD-810 is a potent and selective MCL1 inhibitor with a Kd of 0.3 nM. BRD-810 can specifically block the BH3 binding groove of MCL1, while having little effect on other anti-apoptotic proteins (such as Bcl-2, Bcl-xL). BRD-810 effectively destroys the MCL1-BAK complex (IC50 = 1.2 nM) in cancer cells, rapidly activates Caspase and induces cell apoptosis. BRD-810 can be used in the research of various cancers such as hematological tumors and solid tumors[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2329719-65-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-162858. | |
| BRD9500 | BRD9500 is an orally active phosphodiesterases 3 (PDE3) inhibitor with IC50s of 10 and 27 nM for PDE3A and PDE3B, respectively. Antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1630760-75-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-136350. | |
| BRD9539 | BRD9539 is an inhibitor of euchromatin histone methyltransferase 2 (EHMT2) with an IC50 value of 6.3 μM. It is selective for G9a and PRC2 over SU39H1 and NDMT1 up to a concentration of 40 μM. BRD9539 is a more potent biochemical inhibitor than its methyl-ester analogue BRD4770, with 20% remaining G9a activity compared to 45% of BRD4770 at screening concentration. Synonyms: BRD-9539; BRD 9539. Grade: ≥98%. CAS No. 1374601-41-8. Molecular formula: C24H21N3O3. Mole weight: 399.4. | |
| BRD 9757 | BRD9757 is a potent and selective histone deacetylases 6 (HDAC6) inhibitor with IC50 of 30 nM. It displays selectivity for HDAC6 over Class I HDACS (>20-fold) and Class II HDACs (>400-fold). Synonyms: N-Hydroxy-1-cyclopentene-1-carboxamide; BRD9757; BRD-9757. Grade: ≥98%. CAS No. 1423058-85-8. Molecular formula: C6H9NO2. Mole weight: 127.14. | |
| BRD 9876 | BRD 9876. Group: Biochemicals. Grades: Purified. CAS No. 32703-82-5. Pack Sizes: 50mg. US Biological Life Sciences. | Worldwide |
| BRD 9876 | BRD 9876 is an ATP non-competitive kinesin Eg5 inhibitor. It selectively inhibits microtubule-bound Eg5 leading to an arrest in G2/M phase. Synonyms: BRD9876; BRD-9876; BRD 9876; 6-(1,1-Dimethylethyl)-2,3-naphthalenedicarbonitrile; 6-Tert-Butyl-2,3-naphthalenedicarbonitrile. Grade: ≥99% by HPLC. CAS No. 32703-82-5. Molecular formula: C16H14N2. Mole weight: 234.3. | |
| BRD-IN-3 | BRD-IN-3, a highly potent inhibitor of PCAF bromodomain (BRD) (IC50 = 7 nM), has activity against GCN5 and FALZ. Synonyms: (R,R)-36n; 2-(((3R,5R)-5-(2,3-Dihydrobenzo[b][1,4]dioxin-6-yl)-1-methylpiperidin-3-yl)amino)-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one; 4H-Pyrrolo[3,2-d]pyrimidin-4-one, 2-[[(3R,5R)-5-(2,3-dihydro-1,4-benzodioxin-6-yl)-1-methyl-3-piperidinyl]amino]-3,5-dihydro-3-methyl-; 2-{[(3R,5R)-5-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1-methyl-3-piperidinyl]amino}-3-methyl-3,5-dihydro-4H-pyrrolo[3,2-d]pyrimidin-4-one. Grade: ≥95%. CAS No. 2351938-32-2. Molecular formula: C21H25N5O3. Mole weight: 395.45. | |
| BRD-K98645985 | BRD-K98645985 is a BAF inhibitor that binds ARID1A-specific BAF complexes, prevents nucleosomal positioning, and potently reverses HIV-1 latency, without T cell activation or toxicity. Synonyms: BRD K98645985; BRDK98645985; 1-Isopropyl-3-((3S,6S,7R)-7-methoxy-3,6,9-trimethyl-10-oxo-4-(4-(pyridin-2-yl)benzyl)-3,4,5,6,7,8,9,10-octahydro-2H-benzo[k][1,4,9]oxadiazacyclododecin-12-yl)urea. Grade: >98%. CAS No. 1357647-78-9. Molecular formula: C33H43N5O4. Mole weight: 573.73. | |
| BRD-K98645985 | BRD-K98645985 is a BAF (mammalian SWI/SNF) transcriptional repression inhibitor with an EC50 of ~2.37 μM. BRD-K98645985 binds ARID1A-specific BAF complexes, prevents nucleosomal positioning, and potently reverses HIV-1 latency, without T cell activation or toxicity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1357647-78-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-114268. | |
| BrdU (Bromodeoxyuridine, 5-BrdU) | BrdU (Bromodeoxyuridine) is a nucleoside analog that competes with thymidine for incorporation into DNA, and used in the detection of proliferating cells. Group: Inhibitors. Alternative Names: 5-Bromo-2'-deoxyuridine, BUdR. CAS No. 59-14-3. Pack Sizes: 200mg. Product ID: S7918. Formula: C9H11BrN2O5. Smiles: C1C(C(OC1N2C=C(C(=O)NC2=O)Br)CO)O. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Breathable Membrane | Breathable Membrane. |  |
| Brecanavir | Brecanavir is a tyrosyl-based arylsulfonamide, high-affinity, protease inhibitor (PI) for the treatment of human immunodeficiency virus type-1. This compound potently inhibited HIV-1 in cell culture assays with 50% effective concentrations (EC(50)s) of 0.2 to 0.53 nM and was equally active against HIV strains utilizing either the CXCR4 or CCR5 coreceptor, as was found with other PIs. Brecanavir had a <5-fold increase in EC(50)s against 80% of patient isolates tested and had a greater mean in vitro potency than amprenavir, indinavir, lopinavir, atazanavir, tipranavir, and darunavir. Uses: Hiv-1 protease inhibitor. Synonyms: Brecanavir; UNII-E367I8C7FI; CHEMBL206031; GW-0385; GW-640385; GW-640385X; VX-385; GW0385; GW640385; GW640385X; VX385; GW 0385; GW 640385; GW 640385X; VX 385; [(3aS,4R,6aR)-2,3,3a,4,5,6a-hexahydrofuro[2,3-b]furan-4-yl] N-[(2S,3R)-4-[1,3-benzodioxol-5-ylsulfonyl(2-methylpropyl)amino]-3-hydroxy-1-[4-[(2-methyl-1,3-thiazol-4-yl)methoxy]phenyl]butan-2-yl]carbamate. Grade: ≥98%. CAS No. 313682-08-5. Molecular formula: C33H41N3O10S2. Mole weight: 703.82. | |
| Brefeldin A | Brefeldin is an antibiotic produced by Penicillum brefeldianum S-464, Pen. cyaneum S-ll, Pen. decumbens, Pen. simplicissimum S-543, etc. Brefeldin A has anti-candida, aspergillus and anti-tumor activity. Uses: Antiviral agents. Synonyms: Ascotoxin; Synergisidin; Decumbin; Nectrolide. Grade: >98%. CAS No. 20350-15-6. Molecular formula: C16H24O4. Mole weight: 280.36. | |
| Brefeldin A | Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus[1][2]. Brefeldin A is also an autophagy and mitophagy inhibitor[3]. Brefeldin A inhibits HSV-1 and has anti-cancer activity[5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BFA; Cyanein; Decumbin. CAS No. 20350-15-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16592. | |
| Brefeldin A | 10mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C16H24O4. CAS No. 20350-15-6. Prepack ID 17689223-10mg. Molecular Weight 280.36. See USA prepack pricing. |  |
| Brefeldin A | Brefeldin A (BFA) is a fungal metabolite demonstrated to reversibly interfere with anterograde transport from the endoplasmic reticulumto the Golgi apparatus (1,2). While initially isolated as an antibiotic (3), and does have a wide range of antibiotic activity, it is primarily used as a biological research tool for studying protein transport. Treatment leads to a rapid accumulation of proteins within the ER and collapse of the Golgi stacks. Treatment with BFA can also inhibit protein secretion (4) and prolonged exposure can induce apoptosis (5). The main target of BFA appears to be ADP-ribosylation factor (ARF), which is responsible for association of coat protein to the Golgi membrane (6,7). Group: Biochemicals. Alternative Names: gamma-4-Dihydroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic acid lambda -lactone; Ascotoxin; BFA; Cyanein; Decumbin;g-4-Dihdyroxy-2-(6-hydroxy-1-heptenyl)-4-cyclopentanecrotonic Acid, ?-Lactone, BFA; Cyanein; Decumbin; Synergisidin; Nectrolide. Grades: Purified. CAS No. 20350-15-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C16H24O4, Molecular Weight: 280.36. US Biological Life Sciences. | Worldwide |
| Brefeldin A (BFA chemical) | Brefeldin A (BFA) is a lactone antibiotic and ATPase inhibitor for protein transport with IC50 of 0.2 μM in HCT 116 cells, induces cancer cell differentiation and apoptosis. It could also improve the HDR(homology-directed repair) efficiency and be an enhancer of CRISPR-mediated HDR. Brefeldin A is also an inhibitor of autophagy and mitophagy. Group: Inhibitors. Alternative Names: Cyanein, Decumbin. CAS No. 20350-15-6. Pack Sizes: 5mg. Product ID: S7046. Formula: C16H24O4. Smiles: CC1CCCC=CC2CC(CC2C(C=CC(=O)O1)O)O. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Brefeldin A (Standard) | Brefeldin A (Standard) (BFA (Standard)) is the analytical standard of Rutin. This product is intended for research and analytical applications. Brefeldin A (BFA) is a lactone antibiotic and a specific inhibitor of protein trafficking. Brefeldin A blocks the transport of secreted and membrane proteins from endoplasmic reticulum to Golgi apparatus. Brefeldin A is also an autophagy and mitophagy inhibitor. Brefeldin A inhibits HSV-1 and has anti-cancer activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BFA (Standard); Cyanein (Standard); Decumbin (Standard). CAS No. 20350-15-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16592R. | |
| Brefeldin B | Brefeldin is an antibiotic produced by Penicillum brefeldianum S-464, Pen. cyaneum S-ll, Pen. decumbens, Pen. simplicissimum S-544, etc. Molecular formula: C15H22O4. Mole weight: 266.33. | |
| Brefeldin C | Brefeldin is an antibiotic produced by Penicillum brefeldianum S-464, Pen. cyaneum S-ll, Pen. decumbens, Pen. simplicissimum S-545, etc. Synonyms: (1S,2Z,7S,10Z,12R,13R)-12-hydroxy-7-methyl-8-oxabicyclo[11.3.0]hexadeca-2,10-dien-9-one; 4H-Cyclopent(f)oxacyclotridecin-4-one, 1,6,7,8,9,11a,12,13,14,14a-decahydro-1-hydroxy-6-methyl-, (1R-(1R*,2E,6S*,10E,11aS*,14aR*))-. Grade: 95%. CAS No. 73899-78-2. Molecular formula: C16H24O3. Mole weight: 264.36. | |
| Bremelanotide | Bremelanotide is a peptide melanocortin receptor agonist developed for the treatment of sexual dysfunction, hemorrhagic shock and reperfusion injury. Uses: Bremelanotide is a synthetic peptide drug that has generated a lot of interest in the drug development community due to its potential applications in sexual dysfunction and other conditions. this peptide is a synthetic analog of the natural hormone alpha-msh (melanocyte stimulating hormone) and acts as a non-selective agonist of the melanocortin receptors mc3-r and mc4-r. one of the main areas of. Synonyms: (Ac-Nle4, Asp5, D-Phe7, Lys10)-cyclo-α-MSH (4-10); PT 141; PT-141; PT141. CAS No. 189691-06-3. Molecular formula: C50H68N14O10. Mole weight: 1025.16.Â… | |
| Bremelanotide | Bremelanotide (PT-141) is a melanocortin receptor agonist. Bremelanotide can activate MC4R and increases dopamine release. Bremelanotide induces appetitive sexual behaviors, female mounting behavior, and repetitive self-grooming. Bremelanotide can be used for the research of hypoactive sexual desire disorders[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PT-141. CAS No. 189691-06-3. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-18678. | |
| Bremelanotide Acetate | Bremelanotide (PT-141) Acetate is a melanocortin receptor agonist. Bremelanotide Acetate can activate MC4R and increases dopamine release. Bremelanotide Acetate induces appetitive sexual behaviors, female mounting behavior, and repetitive self-grooming. Bremelanotide Acetate can be used for the research of hypoactive sexual desire disorders[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PT-141 Acetate. CAS No. 1607799-13-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18678A. | |
| Bremelanotide Acetate | Bremelanotide Acetate is a heptapeptide melanocortin agonist. Bremelanotide, formerly known as PT-141, employed in clinical trials for sexual dysfunction including both male erectile dysfunction (ED) and female sexual dysfunction or disorder (FSD), is a f. Synonyms: PT141 acetate. CAS No. 1607799-13-2. Molecular formula: C52H72N14O12. Mole weight: 1085.22. | |
| Bremelanotide Acetate Hydrate | Bremelanotide is a melanocortin receptor agonist shown to improve female sexual function in females suffering from sexual dysfunction. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg, 100mg. Molecular Formula: C52H74N14O13. US Biological Life Sciences. | Worldwide |
| Brenetafusp | Brenetafusp is a TCR/anti-CD3 bispecific fusion protein, consisting of a TCR targeting the PRAME peptide and an anti-CD3 scFv effector domain. Brenetafusp redirects CD3+ T cells to kill PRAME+ tumor cells. Brenetafusp can be used in research related to cutaneous melanoma, non-small cell lung cancer, ovarian cancer, endometrial cancer, triple-negative breast cancer, and small cell lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IMC-F106C. CAS No. 2736407-54-6. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P990717. | |
| Brenipatide | Brenipatide (LY-3537031) is a dual glucagon-like peptide-1 (GLP-1) and gastric inhibitory polypeptide (GIP) receptor agonist. Brenipatide can be used for the study of metabolic disorders, obesity and diabetes[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY-3537031. CAS No. 2408921-49-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P11666. | |
| Brensocatib | Brensocatib (AZD7986) is an oral dipeptidyl peptidase 1 (DPP1) inhibitor with pIC50s of 6.85, 7.6, 7.7, 7.8, and 7.8 in human, mouse, rat, dog and rabbit, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD7986; INS 1007. CAS No. 1802148-05-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-101056. | |
| Brentuximab | Brentuximab (CAC-10) is a chimeric antibody targeting CD30. Brentuximab is conjugated with Monomethyl auristatin E (MMAE) (HY-15162) to form the antibody-drug conjugate Brentuximab vedotin (HY-P99107A). Brentuximab can be used for the research of cancer, such as lymphoma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CAC-10. CAS No. 2088770-90-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P99151. | |
| Brentuximab | Brentuximab is a chimeric antibody directed against CD30, a protein often found at high levels on classical Hodgkin lymphoma cells (called Reed-Sternberg cells). CAS No. 2088770-90-3. | |
| Brentuximab vedotin (solution) | Brentuximab vedotin (solution) (cAC10-vcMMAE) is an antibody-drug conjugate (ADC) comprising an anti-CD30 antibody and the cytotoxic agent Monomethyl auristatin E (MMAE). The antibody portion is Brentuximab (HY-P99151), and the drug-linker conjugate for ADC is VcMMAE (HY-15575). Brentuximab vedotin (solution) inhibits CD30-positive cells with an IC50 of 2.5 ng/mL. Brentuximab vedotin (solution) can be used for the research of relapsed and refractory Hodgkin lymphoma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 914088-09-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99107A. | |
| Brepocitinib | Brepocitinib (PF-06700841) is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-06700841. CAS No. 1883299-62-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-112708. | |
| Brepocitinib P-Tosylate | Brepocitinib (PF-06700841) P-Tosylate is a potent dual Janus kinase 1 (JAK1) and TYK2 inhibitor with IC50s of 17 nM and 23 nM, respectively. Brepocitinib P-Tosylate also inhibits JAK2 and JAK3 with IC50s of 77 nM and 6.49 μM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PF-06700841 P-Tosylate. CAS No. 2140301-96-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-112708A. | |
| Brequinar | Brequinar (DUP785) is a potent inhibitor of dihydroorotate dehydrogenase (DHODH) with an IC50 of 5.2 nM for human DHODH. Brequinar has potent activities against a broad spectrum of viruses. Brequinar also has an anti-SARS2 activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DUP785; NSC 368390. CAS No. 96187-53-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108325. | |
| Brequinar | Brequinar is a synthetic quinolinecarboxylic acid analogue with antineoplastic properties. Brequinar inhibits the enzyme dihydroorotate dehydrogenase, thereby blocking de novo pyrimidine biosynthesis. This agent may also enhance the in vivo antitumor effect of antineoplastic agents such as 5-FU. Check for active clinical trials or closed clinical trials using this agent. Synonyms: DUP785; NSC 368390; 6-Fluoro-2-(2'-fluoro-[1,1'-biphenyl]-4-yl)-3-methylquinoline-4-carboxylic acid; 6-fluoro-2-(2'-fluorobiphenyl-4-yl)-3-methylquinoline-4-carboxylic acid; 4-Quinolinecarboxylic acid, 6-fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-; Biphenquinate. Grade: ≥98%. CAS No. 96187-53-0. Molecular formula: C23H15F2NO2. Mole weight: 375.37. | |
| Brequinar sodium | Brequinar sodium is a potent and selective dihydroorotate dehydrogenase (DHODH) inhibitor (IC50 = ~20 nM), which causes the blockade of de novo pyrimidine nucleotide biosynthesis. Uses: Antineoplastic agents. Synonyms: Dup785; Dup 785; Dup-785; Brequinar Sodium. 6-Fluoro-2-(2'-fluoro[1,1'-biphenyl]-4-yl)-3-methyl-4-quinolinecarboxylic acid sodium; Dup 785. Grade: ≥99% by HPLC. CAS No. 96201-88-6. Molecular formula: C23H14F2NO2Na. Mole weight: 397.35. | |
| Bretazenil | Bretazenil (Ro 16-6028) is a partial agonist at the gamma-aminobutyric acid A (GABAA) receptor-linked benzodiazepine site. Bretazenil is potent benzodiazepine examined, exhibiting an IC50 (concentration at which half-maximal inhibition of specific [35S]TBPS binding occurs) of 6.1 nM. Bretazenil shows an EC50 of 10 nM for recombinant α1β1γ2. Anticonvulsant effects[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ro 16-6028. CAS No. 84379-13-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105056. | |
| Bretazenil | Bretazenil. Group: Biochemicals. Grades: Purified. CAS No. 84379-13-5. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bretisilocin | Bretisilocin (GM-2505) is the agonist for 5-HT2A receptor and a serotonin releaser. Bretisilocin exhibits antidepressant activity and can be used in the study of depression[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GM-2505. CAS No. 2698331-35-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-172420. | |
| Bretylium | Bretylium, a class III antiarrhythmic agent, is an inhibitor of the presynaptic release of vasoconstrictive neurotransmitters and a blocker of sympathetic and adrenergic nerves. Uses: Anti-arrhythmia agents. Synonyms: 2-Bromo-N-ethyl-N,N-dimethylbenzenemethanaminium; (o-Bromobenzyl)ethyldimethylammonium; Bretylan; Bretylate; Bretylol; N-Ethyl-N-(o-bromobenzyl)-N,N-dimethylammonium; NSC62164; Benzenemethanaminium, 2-bromo-N-ethyl-N,N-dimethyl-. Grade: 95%. CAS No. 59-41-6. Molecular formula: C11H17BrN+. Mole weight: 243.16. | |
| Bretylium Tosylate | Bretylium Tosylate, a class III antiarrhythmic agent, is an inhibitor of the presynaptic release of vasoconstrictive neurotransmitters and a blocker of sympathetic and adrenergic nerves. Synonyms: 2-Bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 4-Methylbenzenesulfonate; (o-Bromobenzyl)ethyldimethylammonium p-Toluenesulfonate; (o-Bromobenzyl)ethyldimethylammonium p-Toluenesulfonate; ASL 603; Bretylan; Bretylate; Bretylium p-Toluenesulfonate; Bretylium Tosilate; Bretylol; Darenthin; N-Ethyl-N-(o-bromobenzyl)-N,N-dimethylammonium Tosylate; NSC 62164; Ornid. Grade: ≥95%. CAS No. 61-75-6. Molecular formula: C18H24BrNO3S. Mole weight: 414.36. | |
| Bretylium Tosylate | Bretylium tosylate has a biphasic response, initially inducing norepinephrine release followed by sympathetic ganglionic blockade. Bretylium tosylate is a class III antiarrhythmic agent and a competitive inhibitor of acetylcholinesterase. Group: Biochemicals. Alternative Names: 2-Bromo-N-ethyl-N, N-dimethyl Benzene methanaminium 4-Methyl Benzene sulfonate; (o-Bromobenzyl) ethyldimethylammonium p-Toluenesulfonate; (o-Bromobenzyl) ethyldimethylammonium p-Toluenesulfonate; ASL 603; Bretylan; Bretylate; Bretylium p-Toluenesulfonate; Bretylium Tosilate; Bretylol; Darenthin; N-Ethyl-N-(o-bromobenzyl)-N,N-dimethylammonium Tosylate; NSC 62164; Ornid. Grades: Highly Purified. CAS No. 61-75-6. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Bretylium Tosylate | Bretylium tosylate is a class III antiarrhythmic agent that also exhibits class II (antiadrenergic) properties, used primarily in emergency settings for the treatment of life-threatening ventricular arrhythmias. It is administered intravenously or intramuscularly and acts by suppressing ventricular fibrillation and ventricular tachycardia. The drug is a quaternary ammonium compound that accumulates in sympathetic ganglia and nerve terminals. Applications: It is indicated for the treatment of ventricular fibrillation and hemodynamically unstable ventricular tachycardia that is unresponsive to other antiarrhythmics, particularly in the setting of acute myocardial infarction. however, its use has declined significantly due to the availability of more effective and safer agents such as amiodarone. it remains available as a second-line agent in advanced cardiac life support protocols. Category: Antiarrhythmic apis. Synonyms: Bretylol; Bretylium tosilate; Darentin; Tosilato de bretilio; Tosilate de bretylium; Bretylii tosilas; ASL-603; Bretilio tosilato. CAS No. 61-75-6. Product ID: API0231559. Molecular formula: C18H24BrNO3S. Mole weight: 414.4. EINECS: 200-516-8. InChIKey: KVWNWTZZBKCOPM-UHFFFAOYSA-M. Appearance: White to off-white crystalline powder. |  |
| Brevetoxin-3 | Brevetoxin-3 (PbTx-3) is a potent allosteric voltage-gated Na+ channel activator and has multiple active centers (A-ring lactone, C-42 of R side chain)[1]. Brevetoxin-3 (PbTx-3) has a high affinity to site 5 of the voltage-sensitive Na+ channels, inhibits the inactivation of Na+ channels and prolongs the mean open time of these channels. Brevetoxin-3 (PbTx-3) repeated exposures can lead to prolonged airway hyperresponsiveness (AHR) and lung inflammation[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PbTx-3. CAS No. 85079-48-7. Pack Sizes: 100 μg. Product ID: HY-12545. | |
| Brevetoxin 6 | Brevetoxin 6 is a polyacyl toxoid produced by Ptychodiscus brevis (Gymnodiniuin bervis). Synonyms: Brevetoxin PbTx-6. Molecular formula: C50H70O15. Mole weight: 911.08. | |
| Brevetoxin A | Brevetoxin A is a polyacyl toxoid produced by Ptychodiscus brevis (Gymnodiniuin bervis). It has a strong effect of activating cell membrane sodium channels, and Tetrodotoxin can counteract its activity. Uses: Adcs cytotoxin. Synonyms: Brevetoxin PbTx 1; Ptychodiscus brevis toxin 1. Grade: 98%. CAS No. 98112-41-5. Molecular formula: C49H70O13. Mole weight: 867.06. | |
| Brevetoxin B | Brevetoxin B is a polyacyl toxoid produced by Ptychodiscus brevis (Gymnodiniuin bervis). It has a strong effect of activating cell membrane sodium channels, and Tetrodotoxin can counteract its activity. Synonyms: PbTx-2. Grade: ≥95%. CAS No. 79580-28-2. Molecular formula: C50H70O14. Mole weight: 895.08. | |
| Brevetoxin PbTx-9 | An activator of voltage-sensitive Na+ channels, a suite of cyclic polyether compounds produced naturally by a species of dinoflagellate known as Karenia brevis. A ciguatoxin comprising a linear sequence of ten trans-fused five-, six-, eight- and nine-membered rings. Synonyms: Brevetoxin B, 42-deoxo-41,43-dihydro-42-hydroxy-. Grade: 95 % (HPLC). CAS No. 142353-09-1. Molecular formula: C50H74O14. Mole weight: 899.12. | |
| Brevianamide F | Brevianamide F, belongs to a class of naturally occurring 2,5-diketopiperazines, is produced by the fungi A.fumigates and Aspergillus sp. Synonyms: Cyclo-L-Trp-L-Pro; L-prolyl-L-tryptophan. Grade: ≥95%. CAS No. 38136-70-8. Molecular formula: C16H17N3O2. Mole weight: 283.33. | |
| brevianamide F prenyltransferase (deoxybrevianamide E-forming) | The enzyme from the fungus Aspergilus sp. MF297-2 is specific for brevianamide F, while the enzyme from Aspergillus versicolor accepts a broad range of trytophan-containing cyclic dipeptides. Involved in the biosynthetic pathways of several indole alkaloids such as paraherquamides and malbrancheamides. Group: Enzymes. Synonyms: NotF; BrePT; brevianamide F reverse prenyltransferase. Enzyme Commission Number: EC 2.5.1.109. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2725; brevianamide F prenyltransferase (deoxybrevianamide E-forming); EC 2.5.1.109; NotF; BrePT; brevianamide F reverse prenyltransferase. Cat No: EXWM-2725. |  |
| Brevianamide L | Brevianamide L is an alkaloid metabolite produced by various Streptomyces, Actinomycetes, and Aspergillus strains. CAS No. 1174538-68-1. Molecular formula: C22H23N3O4. Mole weight: 393.44. | |
| Brevicompanine B | Brevicompanine B is a diketopiperazine related metabolite produced by Penicillium and Aspergillus species. Brevicompanine B was found to be active against the malaria parasite Plasmodium falciparum and has been demonstrated to show pronounced plant growth regulatory activity but is devoid of antifungal or antibacterial activity. Group: Biochemicals. Grades: Highly Purified. CAS No. 215121-47-4. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Brevicompanine B | A diketopiperazine-related metabolite produced by penicillium brevicompactum and aspergillus species. It has obvious plant growth regulation activity, but is devoid of antifungal or antimicrobial activity. It is active against Plasmodium falciparum. Synonyms: (3R,5aS,10bR,11aS)-10b-(1,1-dimethyl-2-propen-1-yl)-6,10b,11,11a-tetrahydro-3-(2-methylpropyl)-2H-pyrazino[1',2':1,5]pyrrolo[2,3-b]indole-1,4(3H,5aH)-dione. Grade: >99% by HPLC. CAS No. 215121-47-4. Molecular formula: C22H29N3O2. Mole weight: 367.48. | |
| Brevifolincarboxylic acid | Brevifolincarboxylic acid is a phenolic compound. Brevifolincarboxylic acid can be isolated from Duchesnea chrysantha. Brevifolincarboxylic acid inhibits α-glucosidase with an IC50 value of 323.46 μM. Brevifolincarboxylic acid has an inhibitory effect on the aryl hydrocarbon receptor (AhR). Brevifolincarbacid scavenges ROS. Brevifolincarbacid restores the glucose uptake activity of myotubes. Brevifolincarboxylic acid has antitumor activity against lung and gastric cancer. Brevifolincarbacid can be used in the study of diabetes and inflammatory diseases[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 18490-95-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N4095. | |
| Brevifolincarboxylic acid | Brevifolincarboxylic acid. Alternative Names: 1,2,3,5-tetrahydro-7,8,9-trihydroxy-3,5-dioxo-cyclopenta[c][2]benzopyran-1-carboxylic acid. CAS No. 18490-95-4. Purity: >95.0%. Product ID: FFC-AR-18490954. Molecular formula: C13H8O8. Mole weight: 292.2. IUPAC Name: 7,8,9-trihydroxy-3,5-dioxo-1,2-dihydrocyclopenta[c]isochromene-1-carboxylic acid. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Brevifolincarboxylic acid | Brevifolincarboxylic acid. Group: Biochemicals. Grades: Plant Grade. CAS No. 18490-95-4. Pack Sizes: 10mg. Molecular Formula: C13H8O8, Molecular Weight: 292.2. US Biological Life Sciences. | Worldwide |
| Brevilin A | Brevilin A is an orally active STAT3/JAK inhibitor (STAT3 IC50=?10.6 μM). Brevilin A shows anti-tumor activity, anti-proliferative activity to cancer cells, and can induce apoptosis and autophagy[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 16503-32-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-N2959. | |
| Brevilin A | Brevilin A, also called 6-O-Angeloylplenolina, is a natural sesquiterpenoid found in the herbs of Centipeda minima, it exhibits the antigiardial activity (IC50 = 16.1 μM) and is similarly active in vitro against Entamoeba histolytica (IC50 between 4.5 and 9 μM) and against Plasmodium falciparum (IC50 = 9.42 μM). Brevilin A inhibits janus kinase activity and exhibits both strong STAT3 signal inhibition and STAT3 signal dependent cell growth inhibition. Uses: Anti-giardial. Synonyms: 6-O-Angeloylplenolin. Grade: >91%. CAS No. 16503-32-5. Molecular formula: C20H26O5. Mole weight: 346.4. | |
| Brevinin-1 | The unique antimicrobial peptide named brevinin-1 was isolated from the skin of the frog, Rana brevipoda porsa. The minimum inhibitory concentration of brevinin-1 against the growth of St. aureus and E. coli was determined to be 8 micrograms/ml and 34 micrograms/ml. Synonyms: Brevinin-1; 145963-49-1; brevinin-1 protein, Rana; Brevinin 1; AMGDYQVEJJSZSQ-IMDMOUBVSA-N; Brevinin-1 (KFHEKHHSHRGY-acid); C121H202N28O26S2; RS-2012; C121-H202-N28-O26-S2. CAS No. 145963-49-1. Molecular formula: C121H202N28O26S2. Mole weight: 2529.2. | |
| Brevinin-1-01 | Brevinin-1-01 was found in Amolops sp. jingdongensis. It has antimicrobial activity. | |
| Brevinin-1-AJ1 antimicrobial peptide precursor | Brevinin-1-AJ1 antimicrobial peptide precursor was found in Amolops jingdongensis. It is against E. coli, B. dysenteriae (MIC=9.38 microg/ml), S. aureus, B. subtilis, and C. albicans. | |
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