A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| Brass foil, alloy 260, 0.64mm (0.025in) thick | Brass foil, alloy 260, 0.64mm (0.025in) thick. |  |
| Brass foil, alloy 260, 0.81mm (0.032in) thick | Brass foil, alloy 260, 0.81mm (0.032in) thick. | |
| Brass foil, alloy 260, 1.0mm (0.04in) thick | Brass foil, alloy 260, 1.0mm (0.04in) thick. | |
| Brass foil, alloy 260, 1.3mm (0.05in) thick | Brass foil, alloy 260, 1.3mm (0.05in) thick. | |
| Brass foil, alloy 260, 1.6mm (0.064in) thick | Brass foil, alloy 260, 1.6mm (0.064in) thick. | |
| Brass foil, alloy 260, 2.0mm (0.08in) thick | Brass foil, alloy 260, 2.0mm (0.08in) thick. | |
| Brass gauze, alloy 260, 100 mesh woven from 0.11mm (0.0045in) dia wire | Brass gauze, alloy 260, 100 mesh woven from 0.11mm (0.0045in) dia wire. | |
| Brass gauze, alloy 260, 20 mesh woven from 0.41mm (0.016in) dia wire | Brass gauze, alloy 260, 20 mesh woven from 0.41mm (0.016in) dia wire. Molecular formula: CuPbZn. Mole weight: 336g/mol. SMILES: [Cu].[Zn].[Pb]. InChI: InChI=1S/Cu.Pb.Zn. | |
| Brass gauze, alloy 260, 80 mesh woven from 0.14mm (0.0055in) dia wire; Cu:Zn; 70:30 wt% | Brass gauze, alloy 260, 80 mesh woven from 0.14mm (0.0055in) dia wire; Cu:Zn; 70:30 wt%. | |
| Brassica Alcohol | Brassica Alcohol is a fatty alcohol that is naturally derived from cruciferous vegetables, such as broccoli, cabbage, and mustard seed. It is often used as an emollient and a thickening agent in cosmetic and personal care products, such as moisturizers, lotions, and shampoos. Brassica Alcohol is a sustainable, plant-based ingredient that is considered to be a healthier and safer alternative to synthetic ingredients in beauty products. It is also biodegradable and renewable. CAS No. 661-19-8 / 112-92-5. Product ID: CI-SC-0733. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Brassica Alcohol | Brassica Alcohol. CAS No. 661-19-8. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications. |  |
| Brassicasterol | Brassicasterol. Group: Biochemicals. Alternative Names: (3b,22E)-Ergosta-5,22-dien-3-ol; Ergosta-5,22-dien-3b-ol; 24(R)-Methylcholesta-5,22E-dien-3b-ol. Grades: Highly Purified. CAS No. 474-67-9. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C28H46O. US Biological Life Sciences. |  Worldwide |
| Brassicasterol-(2,2',3,4,4',6-D6) | Brassicasterol-(2,2',3,4,4',6-D6) is derived from Brassicasterol (B676850), which is a phytosterol found in canola oil, rapeseed oil, marine algae and shellfish. This compound has been shown to inhibit sterol Δ24-reductase, an enzyme involved in the mammalian cholesterol biosynthesis pathway. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg, 2.5mg. Molecular Formula: C28H40D6O, Molecular Weight: 404.7. US Biological Life Sciences. | Worldwide |
| Brassicin | Brassicin, a natural Flavonoid, possesses radical scavenging activity[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Isorhamnetin 7-O-glucoside. CAS No. 6743-96-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-N8193. |  |
| Brassinazole | Brassinazole is a selective triazole-type brassinosteroid (BR) biosynthesis inhibitor. Brassinazole is used for regulating plant growth and development[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 280129-83-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-121161A. | |
| Brassinazole | Brassinazole is a potent brassinosteroid (BR) biosynthesis inhibitor that has similar structure to pacrobutrazol. Brassinosteroids are a class of phytohormones with essential roles in plant growth and development, including the promotion of stem elongation and cell division. It has displayed the ability to induce morphological changes in dark-grown Arabidopsis. It can also induce morphological changes, including dwarfism and altered leaf color and curling. Synonyms: Brassinazole. Grade: ≥98%. CAS No. 224047-41-0. Molecular formula: C18H18ClN3O. Mole weight: 327.8. |  |
| Brassinin | Brassinin. Group: Biochemicals. Alternative Names: N- (1H-Indol-3-ylmethyl) carbamodithioic acid. Grades: Highly Purified. CAS No. 105748-59-2. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C11H12N2S2. US Biological Life Sciences. | Worldwide |
| Brassinin | Brassinin is an inhibitor of indoleamine 2,3-dioxygenase (IDO; Ki = 28 μM for human IDO) with antifungal and anticancer activities. Brassinin also inhibits IL-6-inducible STAT3 activation and attenuates tumor growth in a xenograft lung cancer mouse model. Brassinin is found in brassicas. Synonyms: Brassinine; CCG-208623; CCG208623; CCG 208623; HE-005916; HE005916; HE 005916; HE-292778; HE292778; HE292778; Methyl (1H-indol-3-ylmethyl)carbamodithioate. Grade: 98%. CAS No. 105748-59-2. Molecular formula: C11H12N2S2. Mole weight: 236.36. | |
| Brassinolide | 25mg Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C28H48O6. CAS No. 72962-43-7. Prepack ID 90026901-25mg. Molecular Weight 480.68. See USA prepack pricing. |  |
| Brassinolide | Brassinolide is a predominant plant growth modulator that regulate plant cell elongation. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Brassin lactone. CAS No. 72962-43-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-N0273. | |
| Brassinolide | 5mg Pack Size. Group: Analytical Reagents, Biochemicals, Building Blocks, Organics. Formula: C28H48O6. CAS No. 72962-43-7. Prepack ID 90026901-5mg. Molecular Weight 480.68. See USA prepack pricing. | |
| Brass plate, alloy 260, 2.4mm (0.093in) thick | Brass plate, alloy 260, 2.4mm (0.093in) thick. | |
| Brass plate, alloy 260, 3.18mm (0.125in) thick | Brass plate, alloy 260, 3.18mm (0.125in) thick. Molecular formula: CuPbZn. Mole weight: 336g/mol. SMILES: [Cu].[Zn].[Pb]. InChI: InChI=1S/Cu.Pb.Zn. | |
| Brass plate alloy 260, 6.35mm (0.25in) thick | Brass plate alloy 260, 6.35mm (0.25in) thick. | |
| Brass spheres, alloy 260, 12.7mm (0.5in) dia | Brass spheres, alloy 260, 12.7mm (0.5in) dia. Molecular formula: CuPbZn. Mole weight: 336g/mol. SMILES: [Cu].[Zn].[Pb]. InChI: InChI=1S/Cu.Pb.Zn. | |
| Brass spheres, alloy 260, 3.18mm (0.125in) dia | Brass spheres, alloy 260, 3.18mm (0.125in) dia. | |
| Brass spheres, alloy 260, 6.35mm (0.25in) dia | Brass spheres, alloy 260, 6.35mm (0.25in) dia. | |
| Brazikumab | Brazikumab (AMG 139) is a human IgG2 monoclonal antibody, selectively binds the p19 subunit of IL-23, with a KD of 0.138 nM for human IL-23. Brazikumab can be used for the research of Crohn's disease[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AMG 139; MEDI2070. CAS No. 1610353-18-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99485. | |
| Brazilin | Brazilin is a red dye precursor obtained from the heartwood of several species of tropical hardwoods. Brazilin inhibits the cells proliferation, promotes apoptosis, and induces autophagy through the AMPK/mTOR pathway. Brazilin shows chondroprotective and anti-inflammatory activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 474-07-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0072. | |
| Brazilin (For Biological Stains and Dyes) | Brazilin (For Biological Stains and Dyes). Uses: For analytical and research use. Alternative Names: (+)-Brazilin; (6aS,11bR)-7,11b-Dihydro-benz[b]indeno[1,2-d]pyran-3,6a,9,10(6H)-tetrol. CAS No. 474-07-7. Molecular formula: C16H14O5. Mole weight: 286.28. Purity: 98%. Catalog: APB474077. |  |
| Brazil nut oil | Brazil nut oil. Alternative Names: Brazil nut, ext. CAS No. 160965-04-8. Product ID: CI-EO-0005. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Brazzein | Brazzein is a sweet-tasting protein composed of 54 amino acids and is considered as a potential sugar substitute. Uses: Brazzein, a natural sweet protein derived from the fruit of the west african plant pentadiplandra brazzeana, has garnered significant attention in recent years for its potential applications in drug discovery. this unique protein, which is approximately 2,000 times sweeter than sucrose on a weight basis, possesses several properties that make it a promising candidate for various pharmaceutical and. Grade: 90%. Mole weight: 6473. | |
| BrBzGCp2 | BrBzGCp2 is a Glyoxalase 1 (GLO1) inhibitor, with a GC50 of 4.23 μM in HL-60 cells. BrBzGCp2 possesses antitumor and neuroprotective activity[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: S-p-Bromobenzylglutathione cyclopentyl diester. CAS No. 166038-00-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136684. | |
| BRCA1-IN-1 | A novel small-molecule-like BRCA1 inhibitor (IC50= 0.53 μM) (Ki= 0.71 μM). Synonyms: [(3S)-1,1-difluoro-3-[3-(1H-indol-3-yl)propanoylamino]-4-oxo-4-[[2-oxo-2-(4-phenylbutylamino)ethyl]amino]butyl]phosphonic acid. CAS No. 1622262-74-1. Molecular formula: C27H33F2N4O6P. Mole weight: 578.54. | |
| BRCA1-IN-2 | BRCA1-IN-2 is a cell-permeable protein-protein interaction (PPI) inhibitor for BRCA1 with an IC50 of 0.31 μM and a Kd of 0.3 μM. It shows antitumor activities via the disruption of BRCA1 (BRCT)2/protein interactions. Synonyms: N-(4-Phenylbutyl)-2-[[(2S)-2-[[3-(1H-indole-3-yl)propanoyl]amino]-3-(phosphonooxy)propanoyl]amino]acetamide. Grade: 98%. CAS No. 1622262-55-8. Molecular formula: C26H33N4O7P. Mole weight: 544.54. | |
| BRD0209 | BRD0209 is a potent, selective and dual inhibitor of GSK3α/β inhibitor (GSK3α IC50 = 19 nM; GSK3β IC50 = 5 nM). BRD0209 is also a reversible ATP-competitive inhibitor with fast-off kinetics (Ki = 4.2 nM, respectively). BRD0209 is a tricyclic pyrazolotetrahydroquinolinone compound. BRD0209 has the potential for the research of mood disorder diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1597439-87-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117822. | |
| BRD0418 | BRD0418 is a TRIB1 inducer. BRD0418 modulates expression of TRIB1 involved in cholesterol and triglyceride biosynthesis, VLDL production and in LDL uptake in HepG2 cells. Synonyms: BRD-0418; BRD 0418. Grade: >98%. CAS No. 1565827-99-7. Molecular formula: C29H32N2O5. Mole weight: 488.58. | |
| BRD0539 | BRD0539 is a Streptococcus pyogenes Cas9 (SpCas9) inhibitor with an IC50 of 22 μM in an in vitro DNA cleavage assay[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1403838-79-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136251. | |
| BRD0539 | BRD0539 is a cell-permeable and reversible inhibitor of Streptococcus pyogenes Cas9 (SpCas9) with IC50 of 22 μM. Synonyms: BRD 0539; BRD-0539. CAS No. 1403838-79-8. Molecular formula: C25H25FN2O3S. Mole weight: 452.54. | |
| BRD0639 | BRD0639 is a first-in-class PRMT5 inhibitor. BRD0639 can support studies of PBM-dependent PRMT5 activities and the development of novel PRMT5 inhibitors that selectively target these functions. Synonyms: BRD 0639; BRD-0639; 1(6H)-Pyridazineacetamide, 4-chloro-α-methyl-N-[4-methyl-3-[[[2-(2-pyridinyl)ethyl]amino]sulfonyl]phenyl]-6-oxo-, (αS)-; (αS)-4-Chloro-α-methyl-N-[4-methyl-3-[[[2-(2-pyridinyl)ethyl]amino]sulfonyl]phenyl]-6-oxo-1(6H)-pyridazineacetamide; (S)-2-(4-chloro-6-oxopyridazin-1(6H)-yl)-N-(4-methyl-3-(N-(2-(pyridin-2-yl)ethyl)sulfamoyl)phenyl)propanamide. Grade: ≥95%. CAS No. 2760881-74-9. Molecular formula: C21H22ClN5O4S. Mole weight: 475.95. | |
| BRD0639 | BRD0639 is a first-in-class inhibitor of the PRMT5-substrate adaptor interaction. BRD0639 is a PRMT5 binding motif (PBM)-competitive agent that can support studies of PBM dependent PRMT5 activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2760881-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132309. | |
| BRD0705 | BRD0705 is a potent, paralog selective and orally active inhibitor of Glycogen synthase kinase 3α (GSK3α) with IC50 of 66 nM and Kd of 4.8 μM. Synonyms: BRD 0705; BRD-0705. CAS No. 2056261-41-5. Molecular formula: C20H23N3O. Mole weight: 321.42. | |
| BRD0705 | BRD0705 is a potent, paralog selective and orally active GSK3α inhibitor with an IC50 of 66 nM and a Kd of 4.8 μM. BRD0705 displays increased selectivity for GSK3α (8-fold) versus GSK3β (IC50 of 515 nM). BRD0705 can be used for acute myeloid leukemia (AML) research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2056261-41-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116830. | |
| BRD32048 | The ETV1 transcription factor is phosphorylated downstream of MAPK signaling and is acetylated at lysines 33 and 116 by the histone acetyltransferase p300. BRD32048 is an inhibitor of the ETV1 transcription factor oncoprotein. BRD32048 binds ETV1 directly, modulating both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 is a substituted [1,3,5]triazine derivative that inhibits ETV1 transcriptional activity by binding to ETV1 with KD of 17.1 μM, which reduces p300-dependent acetylation and stability of ETV1. Synonyms: BRD-32048; BRD 32048. Grade: ≥98%. CAS No. 433694-46-3. Molecular formula: C16H22N6O. Mole weight: 314.4. | |
| BRD32048 | BRD32048 is a direct binder of ETV1 with a KD of 17.1 μM. BRD32048 modulates both ETV1-mediated transcriptional activity and invasion of ETV1-driven cancer cells. BRD32048 inhibits ETV1 acetylation and promotes its degradation. BRD32048 acts as a top candidate ETV1 perturbagen[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 433694-46-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-116785. | |
| BRD3308 | BRD3308 is a highly selective HDAC3 inhibitor with an IC50 of 54 nM. BRD3308 is 23-fold selectivity for HDAC3 over HDAC1 (IC50 of 1.26 μM) or HDAC2 (IC50 of 1.34 μM). BRD3308 suppresses pancreatic β-cell apoptosis induced by inflammatory cytokines or glucolipotoxic stress, and increases functional insulin release. BRD3308 activates HIV-1 transcription and disrupts HIV-1 latency[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1550053-02-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19618. | |
| BRD3308 | BRD3308 is a highly selective HDAC3 inhibitor with IC50 of 54 nM. BRD3308 inhibits pancreatic β-cell apoptosis induced by inflammatory cytokines or glycolipid toxic stress, and increases the release of functional insulin. BRD3308 activates HIV-1 transcription and destroys the HIV-1 incubation period. Synonyms: 4-Acetylamino-N-(2-Amino-4-Fluorophenyl)-Benzamide; CHEMBL4293858; SCHEMBL15551809; BDBM178100. Grade: 98%. CAS No. 1550053-02-5. Molecular formula: C15H14FN3O2. Mole weight: 287.29. | |
| BRD3731 | BRD3731 is a selective inhibitor of GSK3β, with IC50s of 15 and 215 nM for GSK3β and GSK3α, respectively. It has potential for the study of post-traumatic stress disorder (PTSD), psychiatric disorder, diabetes and neurodegenerative disorders. Synonyms: 5H-Pyrazolo[3,4-b]quinolin-5-one, 3-(2,2-dimethylpropyl)-1,2,4,6,7,8-hexahydro-4,7,7-trimethyl-4-phenyl-, (4S)-; (4S)-3-(2,2-Dimethylpropyl)-4,7,7-trimethyl-4-phenyl-1,2,4,6,7,8-hexahydro-5H-pyrazolo[3,4-b]quinolin-5-one. Grade: ≥98%. CAS No. 2056262-07-6. Molecular formula: C24H31N3O. Mole weight: 377.52. | |
| BRD3731 | BRD3731 is a selective GSK3β inhibitor, with IC50s of 15 nM and 215 nM for GSK3β and GSK3α, respectively. BRD3731 is potentail for the research of post-traumatic stress disorder (PTSD), psychiatric disorder, diabetes, and neurodegenerative disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2056262-07-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-124607B. | |
| BRD 4354 | BRD 4354 is an HDAC5 and HDAC9 inhibitor (IC50 = 0.85 and 1.88 μM, respectively) displaying >20-fold selectivity for HDAC5/9 over HDAC1/2/3. It also weakly inhibits HDAC4, HDAC6, HDAC7 and HDAC8 (IC50 values are 3.88 - 13.8 μM). Synonyms: BRD4354; BRD 4354; BRD-4354; 5-Chloro-7-[(4-ethyl-1-piperazinyl)-3-pyridinylmethyl]-8-quinolinol. Grade: ≥98% by HPLC. CAS No. 315698-07-8. Molecular formula: C21H23ClN4O. Mole weight: 382.89. | |
| BRD 4354 ditrifluoroacetate | BRD 4354 ditrifluoroacetate is a moderately potent HDAC5 and HDAC9 inhibitor with IC50s of 0.85 and 1.88 μM, respectively. Synonyms: 8-Quinolinol, 5-chloro-7-[(4-ethyl-1-piperazinyl)-3-pyridinylmethyl]-, 2,2,2-trifluoroacetate (1:2); 5-Chloro-7-[(4-ethyl-1-piperazinyl)(3-pyridinyl)methyl]-8-quinolinol trifluoroacetate (1:2). CAS No. 2444837-63-0. Molecular formula: C25H25ClF6N4O5. Mole weight: 610.93. | |
| BRD4770 | BRD4770 is a novel histone methyltransferase inhibitor. BRD4770 reduced cellular levels of di- and trimethylated H3K9 without inducing apoptosis, induced senescence, and inhibited both anchorage-dependent and -independent proliferation in the pancreatic cancer cell line PANC-1. ATM-pathway activation, caused by either genetic or small-molecule inhibition of G9a, may mediate BRD4770-induced cell senescence. BRD4770 may be a useful tool to study G9a and its role in senescence and cancer cell biology. Synonyms: BRD4770; BRD-4770; BRD 4770. Grade: 0.98. CAS No. 1374601-40-7. Molecular formula: C25H23N3O3. Mole weight: 413.477. | |
| BRD4884 | BRD4884 is a selective HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1.09 μM for HDAC1, 2, and 3. It possesses preferential binding kinetics with seven-fold longer half-life. BRD4884 crosses the blood brain barrier and has been evaluated in CK-p25 mice, a mouse model of neurodegeneration. It acts by enhancing the learning and memory processes. Synonyms: BRD-4884; BRD 4884. Grade: ≥98%. CAS No. 1404559-91-6. Molecular formula: C18H19FN2O2. Mole weight: 314.4. | |
| BRD4884 | BRD4884 is a potent and brain-penetrant HDAC inhibitor with IC50 values of 29 nM, 62 nM, and 1090 nM for HDAC1, HDAC2, and HDAC3, respectively. BRD4884 can be used for the study of cognitive impairment[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1404559-91-6. Pack Sizes: 10 mM * 1 mL in DMSO; 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-102083. | |
| Brd4 Antibody [D15J2] | Brd4 Antibody [D15J2]. Group: Antibodies. CAS No. Pack Sizes: 20ul. Product ID: F1076. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| BRD4/CK2-IN-1 | BRD4/CK2-IN-1 is an effective and orally active dual-target inhibitor of BRD4/CK2 (bromodomain-containing protein 4/casein kinase 2), with IC50s of 180 nM and 230 nM for BRD4 and CK2, respectively. BRD4/CK2-IN-1 induces apoptosis and autophagy-associated cell death in triple-negative breast cancer (TNBC). Molecular formula: C29H30ClN5O5. Mole weight: 564.03. | |
| BRD4 degrader-1 | BRD4 degrader-1 (Compound mL 1-50) is a relatively selective, monovalent and covalent BRD4 Molecular glue degrader. BRD4 degrader-1 induces degradation of both long and short isoforms of BRD4 by targeting DCAF16 (an E3 ligase). BRD4 degrader-1 can be used in breast cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3094209-54-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163638. | |
| BRD4 degrader AT1 | BRD4 degrader AT1 is a PROTAC connected by ligands for von Hippel-Lindau and BRD4 as a highly selective Brd4 degrader, with a Kd of 44 nM for Brd4BD2 in cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 2098836-45-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111433. | |
| BRD4 Inhibitor-10 | BRD4 Inhibitor-10 (Compound II-25) is a potent BRD4-BD1 inhibitor with an IC50 of 8 nM. BRD4 Inhibitor-10 can be used to study diseases caused by abnormal or excessive cell proliferation, such as cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1660117-38-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117491. | |
| BRD4 Inhibitor-13 | BRD4 Inhibitor-13 (Compound 2) is a BRD4 ligand, and can be used for research of cancer, inflammation. Uses: Scientific research. Category: Signaling pathways. CAS No. 218934-50-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-132130. | |
| BRD5018 | BRD5018 is an antimalarial agent. CAS No. 2245231-51-8. Molecular formula: C33H38N4O4. Mole weight: 554.68. | |
| BRD5529 | BRD5529 is an effective dose-dependent CARD9-TRIM62 protein-protein interaction (PPI) inhibitor with an IC50 value of 8.6 μM. BRD5529 has potency and complete inhibition of CARD9 ubiquitinylation in vitro, also has favorable solubility. BRD5529 can be used for the research of inflammatory bowel disease (IBD) such as Crohns disease (CD) and ulcerative colitis (UC)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1358488-78-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-115497. | |
| BRD5648 | BRD5648 is the inactive enantiomer of rac-BRD0705, which is a potent, paralog selective and orally active inhibitor of GSK3α. Synonyms: (R)-BRD0705; (R)-4-Ethyl-7,7-dimethyl-4-phenyl-6,7,8,9-tetrahydro-2H-pyrazolo[3,4-b]quinolin-5(4H)-one. Grade: 99%. CAS No. 2056261-42-6. Molecular formula: C20H23N3O. Mole weight: 321.42. | |
| BRD6688 | BRD6688 is an HDAC inhibitor with IC50 values of 21 nM, 100 nM, and 11.48 μM for HDAC1, 2, and 3, respectively. It possesses preferential binding kinetics with six-fold extended half-life on HDAC2 compared to HDAC1. It crosses the blood brain barrier and has been shown to rescue the memory defects associated with p25 induced neurodegeneration in contextual fear conditioning in a CK-p25 mouse model of neurodegeneration. Synonyms: BRD-6688; BRD 6688. Grade: ≥98%. CAS No. 1404562-17-9. Molecular formula: C16H18N4O. Mole weight: 282.3. | |
| BRD-6929 | BRD-6929 is a potent, selective brain-penetrant inhibitor of class I histone deacetylase HDAC1 and HDAC2 inhibitor with IC50 of 1 nM and 8 nM, respectively. BRD-6929 shows high-affinity to HDAC1 and HDAC2 with Ki of 0.2 and 1.5 nM, respectively. BRD-6929 can be used for mood-related behavioral model research[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 849234-64-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100719. | |
| BRD6989 | BRD6989, an analog of the natural product cortistatin A (dCA), inhibits CDK8 and upregulates IL-10. BRD6989 selectively binds a complex of CDK8 with an IC50 of ~200 nM. BRD6989 inhibits the kinase activity of recombinant CDK8 or CDK19 complexes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 642008-81-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122586. | |
| BRD 6989 | BRD 6989 is a small molecule inhibitor with high selectivity for CDK8 over CDK19. It is an analog of the natural product cortistatin A (dCA), which inhibits CDK8 and upregulates IL-10. BRD 6989 selectively binds a complex of CDK8 with an IC50 of 200 nM. It also inhibits IFNγ-induced phosphorylation of STAT1 at Ser 727 site in BMDCs. It may be useful for inflammatory disorders. Synonyms: 2-Amino-5,6,7,8-tetrahydro-6-methyl-4-(3-pyridinyl)-3-quinolinecarbonitrile; BRD-6989; BRD6989. Grade: ≥98%. CAS No. 642008-81-9. Molecular formula: C16H16N4. Mole weight: 264.33. | |
| BRD7116 | BRD7116 is an inhibitor of leukemia stem cell (LSC) activity (EC50 = 200 nM) but does not affect normal hematopoietic stem cells or AML cells. Synonyms: BRD-7116; 2,2,3,3-tetramethyl-N-[4-[4-[(2,2,3,3-tetramethylcyclopropanecarbonyl)amino]phenyl]sulfonylphenyl]cyclopropane-1-carboxamide. Grade: >98%. CAS No. 329059-55-4. Molecular formula: C28H36N2O4S. Mole weight: 496.66. | |
| BRD 7389 | BRD 7389 is a ribosomal S6 kinase (RSK) inhibitor (IC50 = 1.2, 1.5 and 2.4 μM for RSK3, RSK1 and RSK2, respectively). It upregulates insulin expression in mouse αTC1 pancreatic α cells. Synonyms: BRD7389; BRD-7389; BRD 7389; BAS 05532738; BAS05532738; BAS-05532738; 1-[(2-Phenylethyl)amino]-3H-naphtho[1,2,3-de]quinoline-2,7-dione. Grade: ≥97% by HPLC. CAS No. 376382-11-5. Molecular formula: C24H18N2O2. Mole weight: 366.41. | |
| BRD 7389 | BRD 7389. Group: Biochemicals. Grades: Purified. CAS No. 376382-11-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
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