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| Product | Description | |
|---|---|---|
| caspase-2 | Caspase-2 is an initiator caspase, as are caspase-8 (EC 3.4.22.61), caspase-9 (EC 3.4.22.62) and caspase-10 (EC 3.4.22.63). Contains a caspase-recruitment domain (CARD) in its N-terminal prodomain, which plays a role in procaspase activation. Two forms of caspase-2 with antagonistic effects exist: caspase-2L induces programmed cell death and caspase-2S suppresses cell death. Caspase-2 is activated by caspase-3 (EC 3.4.22.56), or by a caspase-3-like protease. Activation involves cleavage of the N-terminal prodomain, followed by self-proteolysis between the large and small subunits of pro-caspase-2 and further proteolysis into smaller fragments. Proteolysis occurs at Asp residues and the.s a substrate of the large isoform of pro-caspase-2 (caspase-2L) but not of the short isoform (caspase-2S). Belongs in peptidase family C14. Group: Enzymes. Synonyms: ICH-1; NEDD-2; caspase-2L; caspase-2S; neural precursor cell expressed developmentally down-regulated protein 2; CASP-2; NEDD2 protein. Enzyme Commission Number: EC 3.4.22.55. CAS No. 182372-14-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4230; caspase-2; EC 3.4.22.55; 182372-14-1; ICH-1; NEDD-2; caspase-2L; caspase-2S; neural precursor cell expressed developmentally down-regulated protein 2; CASP-2; NEDD2 protein. Cat No: EXWM-4230. |  |
| caspase-3 | Caspase-3 is an effector/executioner caspase, as are caspase-6 (EC 3.4.22.59) and caspase-7 (EC 3.4.22.60). These caspases are responsible for the proteolysis of the majority of cellular polypeptides [e.g. poly(ADP-ribose) polymerase (PARP)], which leads to the apoptotic phenotype. Procaspase-3 can be activated by caspase-1 (EC 3.4.22.36), caspase-8 (EC 3.4.22.61), caspase-9 (EC 3.4.22.62) and caspase-10 (EC 3.4.22.63) as well as by the serine protease granzyme B. Caspase-3 can activate procaspase-2 (EC 3.4.22.55). Activation occurs by inter-domain cleavage followed by removal of the N-terminal prodomain. Although Asp-Glu-(Val/Ile)-Asp is thought to be the preferred cleavage sequence, the enzyme can accommodate different residues at P2 and P3 of the substrate. Like caspase-2, a hydrophobic residue at P5 of caspase-3 leads to more efficient hydrolysis, e.g. (Val/Leu)-Asp-Val-Ala-Asp? is a better substrate than Asp-Val-Ala-Asp?. This is not the case for caspase-7. Belongs in peptidase family C14. Group: Enzymes. Synonyms: CPP32; apopain; yama protein. Enzyme Commission Number: EC 3.4.22.56. CAS No. 169592-56-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4231; caspase-3; EC 3.4.22.56; 169592-56-7; CPP32; apopain; yama protein. Cat No: EXWM-4231. | |
| Caspase-3/7 Inhibitor I | Caspase-3/7 inhibitor I is a potent, reversible, isatin sulfonamide-based inhibitor of caspase-3 (Ki(app) = 60 nM; IC50 = 120 nM) and caspase-7 (Ki(app) = 170 nM). It is a weaker inhibitor of caspase-9 with Ki(app) of 3.1 μM and caspase-1, caspase-2, caspase-4, caspase-6, and caspase-8 (Ki(app)s ≥25 μM). The basis for the unique selectivity of this compound for caspases 3 and 7 involves the recognition of three distinct hydrophobic residues in the S2 pocket surrounding the catalytic cysteine residue. Grade: ≥98%. CAS No. 1110670-49-9. Molecular formula: C14H16N2O5S. Mole weight: 324.4. |  |
| Caspase3 Antibody [F8M16] | Caspase 3,Caspase-3. Group: Antibodies. Alternative Names: Caspase-3. Pack Sizes: 20ul. Product ID: F1080. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| Caspase 3 Human, Recombinant | Caspase 3 is a member of the CED-3 subfamily of caspases and is responsible for the cleavage of many key proteins such as the nuclear enzyme poly (ADP-ribose) polymerase (PARP), the inhibitor of caspase-activated deoxyribonuclease (ICAD), and gelsolin, a protein involved in apoptosis regulation. Caspase 3 is considered to be an effector caspase, activating pro-caspase 6 and pro-caspase 9 in vitro. Caspase 3 can be activated by caspase 8, caspase 6, and granzyme B. Human recombinant c-terminal histidine tagged caspase 3 is a fully active protein consisting of 17 kda and 13.5 kda subunits; the 13.5 kda subunit contains the histidine tag. Applications: Caspase-3 is a caspase prote.ve enzyme. this protein cleaves and activates caspases 6 and 7; and the protein itself is processed and activated by caspases 8, 9, and 10. it is the predominant caspase involved in the cleavage of amyloid-beta 4a precursor protein, which is associated with neuronal death in alzheimer's disease. alternative splicing of this gene results in two transcript variants that encode the same protein. caspase-3 shares many of the typical characteristics common to all currently-known caspases. for example, its active site contains a cysteine residue (cys-163) and histidine residue (his-121) that stabilize the peptide bond cleavage of a protein sequence to the carboxy-terminal side of an. | |
| Caspase-3-IN-1 | Caspase-3-IN-1 (compound 11b) is a potent Caspase-3 inhibitor, with an IC50 of 14.5 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 872254-32-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-136975. |  |
| Caspase-3 p12 Antibody [N15D21] | caspase-3 p11,Caspase-3 p12. Group: Antibodies. Alternative Names: CPP32, CASP3, Caspase-3, CASP-3, Apopain, Cysteine protease CPP32, Protein Yama, SREBP cleavage activity 1, CPP-32, SCA-1. CAS No. Pack Sizes: 20uL. Product ID: F2459. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| caspase-4 | This enzyme is part of the family of inflammatory caspases, which also includes caspase-1 (EC 3.4.22.36) and caspase-5 (EC 3.4.22.58) in humans and caspase-11 (EC 3.4.22.64), caspase-12, caspase-13 and caspase-14 in mice. Contains a caspase-recruitment domain (CARD) in its N-terminal prodomain, which plays a role in procaspase activation. The enzyme is able to cleave itself and the p30 caspase-1 precursor, but, unlike caspase-1, it is very inefficient at generating mature interleukin-1β (IL-1β) from pro-IL-1&beta. Both this enzyme and caspase-5 can cleave pro-caspase-3 to release the small subunit (p12) but not the large subunit (p17). The caspase-1 inhibitor Ac-Tyr-Val-Ala-Asp-CHO can also inhibit this enzyme, but more slowly. Belongs in peptidase family C14. Group: Enzymes. Synonyms: ICErelII; ICErel-II; Ich-2; transcript X; TX; TX protease; caspase 4; CASP-4. Enzyme Commission Number: EC 3.4.22.57. CAS No. 182762-08-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4232; caspase-4; EC 3.4.22.57; 182762-08-9; ICErelII; ICErel-II; Ich-2; transcript X; TX; TX protease; caspase 4; CASP-4. Cat No: EXWM-4232. | |
| caspase-5 | This enzyme is part of the family of inflammatory caspases, which also includes caspase-1 (EC 3.4.22.36) and caspase-4 (EC 3.4.22.57) in humans and caspase-11 (EC 3.4.22.64), caspase-12, caspase-13 and caspase-14 in mice. Contains a caspase-recruitment domain (CARD) in its N-terminal prodomain, which plays a role in procaspase activation. The enzyme is able to cleave itself and the p30 caspase-1 precursor, but is very inefficient at generating mature interleukin-1β (IL-1β) from pro-IL-1&beta. Both this enzyme and caspase-4 can cleave pro-caspase-3 to release the small subunit (p12) but not the large subunit (p17). Unlike caspase-4, this enzyme can be induced by lipopolysaccharide. Belongs in peptidase family C14. Group: Enzymes. Synonyms: ICErel-III; Ich-3; ICH-3 protease; transcript Y; TY; CASP-5. Enzyme Commission Number: EC 3.4.22.58. CAS No. 192465-11-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4233; caspase-5; EC 3.4.22.58; 192465-11-5; ICErel-III; Ich-3; ICH-3 protease; transcript Y; TY; CASP-5. Cat No: EXWM-4233. | |
| Caspase-5-derived FSP (67-75) | Caspase-5-derived FSP (67-75). | |
| caspase-6 | Caspase-6 is an effector/executioner caspase, as are caspase-3 (EC 3.4.22.56) and caspase-7 (EC 3.4.22.60). These caspases are responsible for the proteolysis of the majority of cellular polypeptides [e.g. poly(ADP-ribose) polymerase (PARP)], which leads to the apoptotic phenotype. Caspase-6 can cleave its prodomain to produce mature caspase-6, which directly activates caspase-8 (EC 3.4.22.61) and leads to the release of cytochrome c from the mitochondria. The release of cytochrome c is an essential component of the intrinsic apoptosis pathway. The enzyme can also cleave and inactivate lamins, the intermediate filament scaffold proteins of the nuclear envelope, leading to nuclear fragmentation in the final phases of apoptosis. Belongs in peptidase family C14. Group: Enzymes. Synonyms: CASP-6; apoptotic protease Mch-2; Mch2. Enzyme Commission Number: EC 3.4.22.59. CAS No. 182372-15-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4234; caspase-6; EC 3.4.22.59; 182372-15-2; CASP-6; apoptotic protease Mch-2; Mch2. Cat No: EXWM-4234. | |
| Caspase-6 (Active) from Human, Recombinant | Caspase-6 is an enzyme that in humans is encoded by the CASP6 gene. This gene encodes a protein that is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein is processed by caspases 7, 8 and 10, and is thought to function as a downstream enzyme in the caspase activation cascade. Caspase 6 can also undergo self-processing without other members of the caspase family. Alternative splicing of this gene results in two transcript variants that encode different isoforms. Group: Enzymes. Synonyms: CASP6; MCH2; Caspase-6 (Active); Caspase-6. Caspase 6. Appearance: Liquid. Storage: -80°C. Form: Liquid. 5μg in 25μl of 50mM TRIS (pH 8.0) containing 100mM sodium chloride and 50mM imidazole. Source: E. coli. Species: Human. CASP6; MCH2; Caspase-6 (Active); Caspase-6. Cat No: NATE-0814. | |
| Caspase-6 Inhibitor Z-VEID-FMK | Caspase-6 Inhibitor Z-VEID-FMK is a caspase-6 inhibitor. Synonyms: Z-VEID-FMK, caspase-6 inhibitor. Grade: >98%. Molecular formula: C31H45FN4O10. Mole weight: 652.9. | |
| caspase-7 | Caspase-7 is an effector/executioner caspase, as are caspase-3 (EC 3.4.22.56) and caspase-6 (EC 3.4.22.59). These caspases are responsible for the proteolysis of the majority of cellular polypeptides [e.g. poly(ADP-ribose) polymerase (PARP)], which leads to the apoptotic phenotype. Although a hydrophobic residue at P5 of caspase-2 (EC 3.4.22.55) and caspase-3 leads to more efficient hydrolysis, the amino-acid residue at this location in caspase-7 has no effect. Caspase-7 is activated by the initiator caspases [caspase-8 (EC 3.4.22.61), caspase-9 (EC 3.4.22.62) and caspase-10 (EC 3.4.22.63)]. Removal of the N-terminal prodomain occurs before cleavage in the linker region between the large and small subunits. Belongs in peptidase family C14. Group: Enzymes. Synonyms: CASP-7; ICE-like apoptotic protease 3; ICE-LAP3; apoptotic protease Mch-3; Mch3; CMH-1. Enzyme Commission Number: EC 3.4.22.60. CAS No. 189258-14-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4236; caspase-7; EC 3.4.22.60; 189258-14-8; CASP-7; ICE-like apoptotic protease 3; ICE-LAP3; apoptotic protease Mch-3; Mch3; CMH-1. Cat No: EXWM-4236. | |
| Caspase-7 from Human, Recombinant | Caspase-7 is a member of the caspase (cysteine aspartate protease) family of proteins, and has been shown to be an executioner protein of apoptosis. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing by upstream caspases (caspase-8, -9) at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme in the form of a heterotetramer. The precursor of this caspase is cleaved by caspase 3, caspase 10, and caspase 9. It is activated upon cell death stimuli and induces apoptosis. Alternative splicing results in four transcript variants, encoding three distinct isoforms. Applications: Used to screen caspase inhibitors, study enzyme regulation, determine caspase substrate specificity, or as positive control in caspase activity assays. Group: Enzymes. Synonyms: CASP7; CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3; Caspase-7. Enzyme Commission Number: EC 3.4.22.-. Purity: 90% (SDS-PAGE). Caspase 7. Activity: ~25,000U/mg protein. Appearance: Lyophilized. Storage: -80°C. Source: E. coli. Species: Human. CASP7; CASP-7; CMH-1; ICE-LAP3; LICE2; MCH3; Caspase-7. Cat No: NATE-0815. | |
| caspase-8 | Caspase-8 is an initiator caspase, as are caspase-2 (EC 3.4.22.55), caspase-9 (EC 3.4.22.62) and caspase-10 (EC 3.4.22.63). Caspase-8 is the apical activator of the extrinsic (death receptor) apoptosis pathway, triggered by death receptor ligation. It contains two tandem death effector domains (DEDs) in its N-terminal prodomain, and these play a role in procaspase activation. This enzyme is linked to cell surface death receptors such as Fas. When Fas is aggregated by the Fas ligand, procaspase-8 is recruited to the death receptor where it is activated. The enzyme has a preference for Glu at P3 and prefers small residues, such as Gly, Ser and Ala, at the P1' position. It has very broad P.ORT1-associated CED-3 homolog; Mch5; mammalian Ced-3 homolog 5; CASP-8; ICE-like apoptotic protease 5; FADD-homologous ICE/CED-3-like protease; apoptotic cysteine protease; apoptotic protease Mch-5; CAP4. Enzyme Commission Number: EC 3.4.22.61. CAS No. 179241-78-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4237; caspase-8; EC 3.4.22.61; 179241-78-2; FLICE, FADD-like ICE; MACH; MORT1-associated CED-3 homolog; Mch5; mammalian Ced-3 homolog 5; CASP-8; ICE-like apoptotic protease 5; FADD-homologous ICE/CED-3-like protease; apoptotic cysteine protease; apoptotic protease Mch-5; CAP4. Cat No: EXWM-4237. | |
| caspase-9 | Caspase-9 is an initiator caspase, as are caspase -2 (EC 3.4.22.55), caspase-8 (EC 3.4.22.61) and caspase-10 (EC 3.4.22.63). Caspase-9 contains a caspase-recruitment domain (CARD) in its N-terminal prodomain, which plays a role in procaspase activation. An alternatively spliced version of caspase-9 also exists, caspase-9S, that inhibits apoptosis, similar to the situation found with caspase-2. Phosphorylation of caspase-9 from some species by Akt, a serine-threonine protein kinase, inhibits caspase activity in vitro and caspase activation in vivo. The activity of caspase-9 is increased dramatically upon association with the apoptosome but the enzyme can be activated without proteolytic cleavage. Procaspase-3 is the enzyme's physiological substrate. Belongs in peptidase family C14. Group: Enzymes. Synonyms: CASP-9; ICE-like apoptotic protease 6; ICE-LAP6; apoptotic protease Mch-6; apoptotic protease-activating factor 3; APAF-3. Enzyme Commission Number: EC 3.4.22.62. CAS No. 180189-96-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4238; caspase-9; EC 3.4.22.62; 180189-96-2; CASP-9; ICE-like apoptotic protease 6; ICE-LAP6; apoptotic protease Mch-6; apoptotic protease-activating factor 3; APAF-3. Cat No: EXWM-4238. | |
| Caspase-9 (Active) from Human, Recombinant | The expressed caspase-9 spontaneously undergoes autoprocessing to yield the subunits characteristic of the native enzyme. Active enzyme purified from E. coliThis product is useful in screening caspase inhibitors for pharmaceutical Applications. Group: Enzymes. Synonyms: CASP9; APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56; Caspase-9 (Active); Caspase-9. Purity: 90% (SDS-PAGE). Caspase 9. Activity: ~400 units/mg. Appearance: Lyophilized Powder. Storage: -80°C. Source: E. coli. Species: Human. CASP9; APAF-3; APAF3; ICE-LAP6; MCH6; PPP1R56; Caspase-9 (Active); Caspase-9. Cat No: NATE-0816. | |
| Caspase-9 Inhibitor III | Caspase-9 Inhibitor III is a potent and irreversible inhibitor of caspase-9 with cardioprotective effects. Caspase inhibitors play an important role in investigating biological processes. Caspase-9 can reduce infarct size, lactate dehydrogenase (LDH) and creatine kinase (CK) release, and DNA smearing induced by ischemia and reperfusion in isolated rat hearts. The caspase family of proteins function as key components of the apoptotic machinery and act to destroy specific target proteins which are critical to cellular longevity. Synonyms: Ac-LEHD-CMK. Grade: 98%. CAS No. 403848-57-7. Molecular formula: C24H35ClN6O9. Mole weight: 587.02. | |
| Caspase-9 Inhibitor III | Caspase-9 Inhibitor III (Ac-LEHD-cmk) is a caspase-9 inhibitor. Caspase-9 Inhibitor III exhibits protective effects on ischemia-reperfusion-induced myocardial injury[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Ac-LEHD-cmk. CAS No. 403848-57-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-136744. | |
| Caspase-9 Inhibitor Z-LEHD-FMK | Caspase-9 Inhibitor Z-LEHD-FMK is a synthetic peptide inhibitor that inhibits the activity of caspase-9 and related caspase. Grade: >98%. CAS No. 210345-04-3. Molecular formula: C32H43FN6O10. Mole weight: 690.7. | |
| Caspofungin | Caspofungin can be used to treat neutropenia, suspected fungal infections in patients with fever, and aggressive aspergillosis that does not respond to or is not tolerated by other treatments. Category: Active pharmaceutical ingredients. CAS No. 179463-17-3. Product ID: API179463173. Molecular formula: C52H88N10O15 · 2C2H4O2. Mole weight: 1213.42. Standard: In House. |  |
| Caspofungin | Caspofungin is a potent antifungal agent. Caspofungin inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0991; L-743872. CAS No. 162808-62-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17006A. | |
| Caspofungin | Caspofungin. Group: Biochemicals. Grades: Highly Purified. CAS No. 162808-62-0. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C53H89N9O15. US Biological Life Sciences. |  Worldwide |
| Caspofungin | Caspofungin acetate is the first in a new class of antifungals that inhibits the synthesis of beta (1, 3)-d-glucan, an essential component of the cell wall of filamentous fungi. CAS No. 162808-62-0. Molecular formula: C52H88N10O15. Mole weight: 1093.31. | |
| Caspofungin acetate | Caspofungin acetate is the first in a new class of antifungals that inhibits the synthesis of beta (1, 3)-d-glucan, an essential component of the cell wall of filamentous fungi. Synonyms: MK-0991; MK 0991; MK0991; caspofungin diacetate; Cancidas; L 743872; L 743873; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate. Grade: 98%. CAS No. 179463-17-3. Molecular formula: C56H96N10O19. Mole weight: 1213.42. | |
| Caspofungin Acetate | An echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. An antifungal drug used in the treatment of invasive fungal infections. Group: Biochemicals. Alternative Names: 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate; Cancidas; Caspofungin Diacetate; L 743872; L 743873; MK 0991; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate. Grades: Highly Purified. CAS No. 179463-17-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg. Molecular Formula: C??H??N??O??, Molecular Weight: 1213.42. US Biological Life Sciences. | Worldwide |
| Caspofungin Acetate C0 Analog | Caspofungin Acetate C0 Analog is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C56H95N10O19. Mole weight: 1212.41. | |
| Caspofungin Acetate-d4 | Isotope labelled Caspofungin Acetate, an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall. An antifungal drug used in the treatment of invasive fungal infections. Group: Biochemicals. Alternative Names: 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-(threo-3-hydroxy-L-ornithine)pneumocandin B0 Diacetate-d4; Cancidas-d4; Caspofungin Diacetate-d4; L 743872-d4; L 743873-d4; MK 0991-d4; 1-[(4R,5S)-5-[(2-Aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]pneumocandin B0 Diacetate-d4. Grades: Highly Purified. CAS No. 1131958-73-0, Unlabelled: 179463-17-3. Pack Sizes: 500ug. Molecular Formula: C??H??D?N??O??, Molecular Weight: 1217.44. US Biological Life Sciences. | Worldwide |
| Caspofungin diacetate | Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0991 diacetate; L-743872 diacetate. CAS No. 179463-17-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-17006. | |
| Caspofungin diacetate | 5mg Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C52H88N10O15 · 2C2H4O2. CAS No. 179463-17-3. Prepack ID 90026800-5mg. Molecular Weight 1213.42. See USA prepack pricing. |  |
| Caspofungin diacetate (Standard) | Caspofungin (diacetate) (Standard) is the analytical standard of Caspofungin (diacetate). This product is intended for research and analytical applications. Caspofungin (MK-0991) diacetate is a potent antifungal agent. Caspofungin diacetate inhibits the synthesis of the fungal cell wall component β-(l,3)-D-glucan[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-0991 diacetate (Standard); L-743872 diacetate (Standard). CAS No. 179463-17-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17006R. | |
| Caspofungin Impurity 1 | Caspofungin Impurity 1 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C50H82N8O16. Mole weight: 1051.23. | |
| Caspofungin Impurity 10 | Caspofungin Impurity 10 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C53H90N10O15. Mole weight: 1107.34. | |
| Caspofungin Impurity 11 | Caspofungin Impurity 11 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C102H168N18O30. Mole weight: 2126.52. | |
| Caspofungin Impurity 13 | Caspofungin Impurity 13 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Synonyms: (3S)-(4R)-1-(10,12-Dimethyl-1-oxotetradecyl)-4,5-dihydroxy-D-prolyl-L-threonyl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3R)-3-hydroxy-L-ornithyl-3-hydroxy-L-prolinamide; 5-Des(2-aminoethylamino)-5-hydroxy-4,5-seco-5,9-cyclo Caspofungin. CAS No. 314080-31-4. Molecular formula: C50H82N8O16. Mole weight: 1051.23. | |
| Caspofungin Impurity 13 | Caspofungin Impurity 13. Uses: For analytical and research use. Alternative Names: N-((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-12-methyltetradecanamide acetate. Molecular formula: C51H86N10O15·C2H4O2. Mole weight: 1139.34. Catalog: APB04701. |  |
| Caspofungin Impurity 14 | Caspofungin Impurity 14. Uses: For analytical and research use. Alternative Names: N-((2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12,15-tetrahydroxy-6-(hydroxymethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide acetate. Molecular formula: C51H82N8O19. Mole weight: 1111.24. Catalog: APB04703. | |
| Caspofungin Impurity 14 | Caspofungin Impurity 14 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C52H88N10O15. Mole weight: 1093.31. | |
| Caspofungin Impurity 15 | Caspofungin Impurity 15 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C57H86N8O16S. Mole weight: 1171.40. | |
| Caspofungin Impurity 15 | Caspofungin Impurity 15. Uses: For analytical and research use. Alternative Names: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-di. CAS No. 1404083-47-1. Molecular formula: C52H86N10O16. Mole weight: 1107.3. Catalog: APB1404083471. | |
| Caspofungin Impurity 16 | Caspofungin Impurity 16 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C57H88N8O15S. Mole weight: 1157.41. | |
| Caspofungin Impurity 17 | Caspofungin Impurity 17 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C52H88N10O14. Mole weight: 1077.31. | |
| Caspofungin Impurity 18 | Caspofungin Impurity 18. Uses: For analytical and research use. Alternative Names: (10R,12S)-N-((2R,6S,9S,11R,12R,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12,15-tetrahydroxy-6-(hydroxymethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide. Molecular formula: C49H78N8O17. Mole weight: 1051.19. Catalog: APB01914. | |
| Caspofungin Impurity 18 Acetate | Caspofungin Impurity 18 Acetate is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C52H86N8O18. Mole weight: 1111.28. | |
| Caspofungin Impurity 19 | Caspofungin Impurity 19 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C52H88N10O15. Mole weight: 1093.31. | |
| Caspofungin Impurity 19 | Caspofungin Impurity 19. Uses: For analytical and research use. Alternative Names: (2S,4S)-N-((2S,3R)-1-((2S,4R)-2-(((2S,3S,4S)-1-(((2S,3R)-5-amino-1-((2S,3S)-2-carbamoyl-3-hydroxypyrrolidin-1-yl)-3-hydroxy-1-oxopentan-2-yl)amino)-3,4-dihydroxy-4-(4-hydroxyphenyl)-1-oxobutan-2-yl)carbamoyl)-4-hydroxypyrrolidin-1-yl)-3-hydroxy-1-oxobutan-2-yl)-1-((10R,12S)-10,12-dimethyltetradecanoyl)-4,5-dihydroxypyrrolidine-2-carboxamide. Molecular formula: C50H82N8O16. Mole weight: 1051.23. Catalog: APB01915. | |
| Caspofungin Impurity 20 | Caspofungin Impurity 20. Uses: For analytical and research use. Alternative Names: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-12-((2-(((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-9-((10R,12S)-10,12-dimethyltetradecanamido)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-12-yl)amino)ethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide. Molecular formula: C102H168N18O30. Mole weight: 2126.53. Catalog: APB01913. | |
| Caspofungin Impurity 21 | Caspofungin Impurity 21. Uses: For analytical and research use. Alternative Names: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,16R,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,16-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide. Molecular formula: C52H88N10O15. Mole weight: 1093.31. Catalog: APB01912. | |
| Caspofungin Impurity 22 | Caspofungin Impurity 22. Uses: For analytical and research use. Alternative Names: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2R)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide. Molecular formula: C52H88N10O15. Mole weight: 1093.31. Catalog: APB01911. | |
| Caspofungin Impurity 22 | Caspofungin Impurity 22 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C49H78N8O17. Mole weight: 1051.18. | |
| Caspofungin Impurity 23 | Caspofungin Impurity 23 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C50H80N8O16. Mole weight: 1049.21. | |
| Caspofungin Impurity 23 | Caspofungin Impurity 23. Uses: For analytical and research use. Alternative Names: (10R,12S)-N-((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide. Molecular formula: C52H88N10O15. Mole weight: 1093.31. Catalog: APB01910. | |
| Caspofungin Impurity 24 | Caspofungin Impurity 24. Uses: For analytical and research use. Alternative Names: N-((2R,6S,9S,11R,12S,14aS,16R,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,16-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide. Molecular formula: C52H88N10O15·2CH3COOH. Mole weight: 1213.41. Catalog: APB04700. | |
| Caspofungin Impurity 24 | Caspofungin Impurity 24 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C50H80N8O16. Mole weight: 1049.21. | |
| Caspofungin Impurity 25 | Caspofungin Impurity 25 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C62H104N8O19S. Mole weight: 1297.59. | |
| Caspofungin Impurity 25 | Caspofungin Impurity 25. Uses: For analytical and research use. Alternative Names: N-((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxy-3-oxopropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide acetate. Molecular formula: C52H86N10O16·CH3COOH. Mole weight: 1167.35. Catalog: APB04699. | |
| Caspofungin Impurity 26 | Caspofungin Impurity 26. Uses: For analytical and research use. Alternative Names: (2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-9-((10,12-dimethyltetradecyl)amino)-2,11,15-trihydroxy-6-((R)-1-hydroxyethyl)hexadecahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosine-5,8,14,19,22,25(9H,25aH)-hexaone. Molecular formula: C52H90N10O14. Mole weight: 1079.33. Catalog: APB04698. | |
| Caspofungin Impurity 26 | Caspofungin Impurity 26 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C51H86N10O15. Mole weight: 1079.28. | |
| Caspofungin Impurity 27 | Caspofungin Impurity 27. Uses: For analytical and research use. Alternative Names: N-((2R,6S,9S,11R,12S,14aS,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-12-((2-aminoethyl)amino)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,15-trihydroxy-6-(hydroxymethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide acetate. Molecular formula: C51H86N10O15·CH3COOH. Mole weight: 1139.34. Catalog: APB04697. | |
| Caspofungin Impurity 28 | Caspofungin Impurity 28. Uses: For analytical and research use. Alternative Names: N-((2R,6S,9S,11R,12R,14aR,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide. Molecular formula: C50H82N8O16. Mole weight: 1051.23. Catalog: APB04696. | |
| Caspofungin Impurity 28 (Acetate) | Caspofungin Impurity 28 (Acetate). Uses: For analytical and research use. Alternative Names: N-((2R,6S,9S,11R,12R,14aR,15S,20S,23S,25aS)-20-((R)-3-amino-1-hydroxypropyl)-23-((1S,2S)-1,2-dihydroxy-2-(4-hydroxyphenyl)ethyl)-2,11,12,15-tetrahydroxy-6-((R)-1-hydroxyethyl)-5,8,14,19,22,25-hexaoxotetracosahydro-1H-dipyrrolo[2,1-c:2',1'-l][1,4,7,10,13,16]hexaazacyclohenicosin-9-yl)-10,12-dimethyltetradecanamide acetate. Molecular formula: C50H82N8O16·C2H4O2. Mole weight: 1111.28. Catalog: APB04694. | |
| Caspofungin Impurity 3 | Caspofungin Impurity 3 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C56H84N8O16S. Mole weight: 1157.37. | |
| Caspofungin Impurity 3 | Caspofungin Impurity 3. Uses: For analytical and research use. Molecular formula: C52H87N11O16. Mole weight: 1122.33. Catalog: APB12131. | |
| Caspofungin Impurity 4 | Caspofungin Impurity 4 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C56H86N8O15S. Mole weight: 1143.39. | |
| Caspofungin Impurity 6 Diacetate | Caspofungin Impurity 6 Diacetate is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C56H96N10O20. Mole weight: 1229.41. | |
| Caspofungin Impurity 7 Diacetate | Caspofungin Impurity 7 Diacetate is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C56H94N10O20. Mole weight: 1227.40. | |
| Caspofungin Impurity 8 | Caspofungin Impurity 8 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C52H90N10O14. Mole weight: 1079.33. | |
| Caspofungin Impurity 9 | Caspofungin Impurity 9 is an impurity of Caspofungin acetate which is an essential component of the cell wall of filamentous fungi. Molecular formula: C52H88N10O15. Mole weight: 1093.31. | |
| Caspofungin Impurity A | Caspofungin Impurity A, is a metabolite of Caspofungin, which is an echinocandin that inhibits the synthesis of β (1,3)-D-glucan, an integral component of the fungal cell wall, and thus used as an antifungal drug. Synonyms: (3S)-(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithyl-L-seryl-(4R)-4-hydroxy-L-prolyl-(4S)-4-hydroxy-4-(4-hydroxyphenyl)-L-threonyl-(3R)-3-hydroxy-L-ornithyl-3-hydroxy-L-proline; EX-A3042. Grade: 90%. CAS No. 1202167-57-4. Molecular formula: C51H86N10O15. Mole weight: 1097.31. | |
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