A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
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| Product | Description | |
|---|---|---|
| Cavaol E | Cavaol E is a natural compound commonly found in plants with potential biomedical applications. Studies have shown that Cavaol E exhibits antioxidant and anti-inflammatory properties, making it a promising candidate for studying oxidative stress-related diseases such as cancer and cardiovascular disorders. CAS No. 1233044-20-6. Molecular formula: C25H36O9. Mole weight: 480.555. |  |
| Caveolin-1 (82-101) amide (human, mouse, rat) | Caveolin-1 (82-101) amide (human, mouse, rat) (Caveolin-1 scaffolding domain peptide) is a peptide that reverses aging-associated deleterious changes in multiple organs. Caveolin-1 (82-101) amide (human, mouse, rat) inhibits tyrosine kinases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Caveolin-1 scaffolding domain peptide. CAS No. 2757108-69-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5904. |  |
| Caveolin-1 Antibody [C16P21] | Caveolin 1,Caveolin-1. Group: Antibodies. Alternative Names: Caveolin 1. Pack Sizes: 20ul. Product ID: F0224. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| CAY10471 | CAY10471 (TM30089) is a potent, selective, and orally active prostaglandin D2 receptor CRTH2 antagonist. CAY10471 attenuates the progression of tubulointerstitial fibrosis and chronic contact hypersensitivity (CHS) in animal model[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: TM30089. CAS No. 627865-18-3. Pack Sizes: 1 mg. Product ID: HY-13706A. | |
| CAY10499 | CAY10499 (MAGL-IN-5) is a non-selective lipase inhibitor with IC50 values of 144 nM and 14 nM for monoacylglycerol lipase (MAGL) and fatty acid amide hydrolase (FAAH), respectively. Additionally, CAY10499 exhibits anti-inflammatory and antiviral activities[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MAGL-IN-5. CAS No. 359714-55-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119283. | |
| CAY10499 | Monoglyceride lipase (MGL) plays an important role in the metabolism of the lipid transmitter 2-arachidonoylglycerol (2-AG). CAY10499 is a potent and selective monoglyceride lipase (MGL) inhibitor exhibiting an IC50 of 90 nM for the recombinant enzyme. It is also a non-selective lipase inhibitor (IC50s = 144, 90, and 14 nM for human recombinant MAGL, HSL, and FAAH, respectively). CAY10499 inhibits the growth of MCF-7, MDA-MB-231, COV318, and OVCAR-3 cancer cells (IC50s = 4.2, 46, 106.7, and 79.8 mM, respectively). Alternative Names: CAY-10499; CAY 10499; Magl-IN-5. Grades: ≥98%. CAS No. 359714-55-9. Molecular formula: C18H17N3O5. Mole weight: 355.34. | |
| CAY10566 | CAY10566 is a potent, orally bioavailable and selective stearoyl-CoA desaturase1 (SCD1) inhibitor with IC50s of 4.5 and 26 nM in mouse and human enzymatic assays, respectively.CAY10566 also shows excellent cellular activity in blocking the conversion of saturated long-chain fatty acid-CoAs (LCFA-CoAs) to monounsaturated LCFA-CoAs in HepG2 cells (IC50=7.9 nM or 6.8 nM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 944808-88-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg; 1 g. Product ID: HY-15823. | |
| CAY10580 | CAY10580 is a potent and selective prostaglandin EP4 receptor agonist (Ki=35 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 64054-40-6. Pack Sizes: 1 mg (14.64 mM * 200 μL in Ethanol). Product ID: HY-135259. | |
| CAY10594 | CAY10594 is an orally active PLD2 inhibitor with an IC50 of 140 nM. CAY10594 has activities such as anti-tumor, anti-oxidation and liver protection. CAY10594 can be used for the research of diseases like breast cancer, acute liver injury and colitis[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1130067-34-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121983. | |
| CAY10602 | CAY10602 is a SIRT1 activator. CAY10602 dose-dependently suppresses the NF-κB-dependent induction of TNF-α by lipopolysaccharide in THP-1 cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 374922-43-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-104073. | |
| CAY10603 | CAY10603 (BML-281) is a potent and selective HDAC6 inhibitor, with an IC50 of 2 pM; CAY10603 (BML-281) also inhibits HDAC1, HDAC2, HDAC3, HDAC8, HDAC10, with IC50s of 271, 252, 0.42, 6851, 90.7 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: BML-281. CAS No. 1045792-66-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-18613. | |
| CAY10650 | CAY10650 is a highly potent cytosolic phospholipase A2α (cPLA2α) inhibitor with an IC50 value of 12 nM. CAY10650 suppresses lipid droplets formation and PGE2 secretion[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1233706-88-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10801. | |
| CAY10731 | CAY10731 (compound 3) is a highly selective fluorescent probe for detection of hydrogen sulfide (H2S). CAY10731 is used to monitor exo- and endogenous H2S in both cancer and normal cells. CAY10731 is applied for imaging of H2S in living tissues at variable depths and in nematodes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2119597-33-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-D1275. | |
| CAY10746 | CAY10746 is a selective Rho kinase (ROCK) inhibitor. CAY10746 has inhibitory activity for ROCK I, ROCK II with IC50 values of 0.014 μM and 0.003 μM, respectively. CAY10746 can be used for the research of diabetic retinopathy (DR)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2247240-76-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139170. | |
| Cayenne Pepper Powder | Cayenne Pepper Powder. |  CA, FL & NJ |
| CAzomethine-H monosodium salt monohydrate | CAzomethine-H monosodium salt monohydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 206752-32-1. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C17H12NNaO8S2·H2O. US Biological Life Sciences. |  Worldwide |
| CB07-Exatecan | CB07-Exatecan is an ADC drug-Linker conjugate that can be used for the synthesis of ADCs. ADC conjugated with CB07-Exatecan and trastuzumab inhibits the growth of HER2-positive cancer cells. CB07-Exatecan can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2879247-31-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-160015. | |
| CB1151 | CB1151 is a 20-epi analogue of 1,25 dihydroxyvitamin D3 (VD) with potent anti-tumor effects. CB1151 inhibits MCF-7 cell growth with an IC50 value of 0.82 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 182369-28-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-100219. | |
| CB1/2 agonist 3 | CB1/2 agonist 3 (compound 52), a potent non-selective cannabinoid ligand, is a CB1/CB2 (cannabinoid receptor) competitive agonist. CB1/2 agonist 3 acts on hCB1 and hCB2 with Ki values of 5.9 nM and 3.5 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2772655-86-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150029. | |
| CB1 agonist 1 | CB1 agonist 1 (compound 22) is an agonist of CB1. CB1 agonist 1 shows affinity to CB1 receptor with an pIC50 value of 5.7. CB1 agonist 1 can be used for the research of brain disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 851212-80-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148137. | |
| CB1 antagonist 2 | CB1 antagonist 2 (AM4113) is an orally active cannabinoid receptor type 1 (CB1R) antagonist. CB1 antagonist 2 suppresses appetite, reduces body weight, and blocks addictive behaviors such as heroin addiction, without causing adverse effects like nausea and depression that are associated with traditional CB1 inverse agonists. CB1 antagonist 2 can be used in studies related to obesity and opioid addiction[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AM4113. CAS No. 614726-85-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-116649. | |
| CB-25-I | CB-25-I, a water-soluble dipeptide, is produced by the strain of Serratia plymuthica. It has an inhibitory effect on individual Candida bacteria (Condida albicans M-9, C. guilliermondii IFO 0454). Alternative Names: N-(R,R)-3-epoxysuccinamoyl-(S)-2,3-diaminopropanoyl-L-valine; Nbeta-(R,R)-epoxysuccinamoyl-(S)-2,3-diaminopropanoyl-L-valine. Molecular formula: C12H20N4O6. Mole weight: 316.31. | |
| CB-5083 | CB-5083 is a first-in-class, potent, selective, and orally bioavailable inhibitor of the p97 AAA ATPase/VCP. CB-5083 selectively inhibits p97 through its D2 site with the IC50 of 11 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1542705-92-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12861. | |
| CB-5339 | CB-5339 is an oral activity potent p97 inhibitor with an IC50 <30 nM. CB-5339 can be used for leukemia research[1]. CB-5339 extracted from WO2015109285A1 compound FF07. Uses: Scientific research. Category: Signaling pathways. CAS No. 1863952-15-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-128724. | |
| CB-6644 | CB-6644 is a selective inhibitor of RUVBL1/2 complex with anti-cancer activity. CB-6644 blocks the ATPase activity of RUVBL1/2 with an IC50 of 15 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2316817-88-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114429. | |
| CB-6644 | CB-6644 is a novel allosteric selective inhibitor of the ruvbl1/2 complex with anti-cancer activity. It blocks the ATPase activity of RUVBL1/2 with an IC50 of 15 nM. Alternative Names: CB 6644; CB6644. CAS No. 2316817-88-4. Molecular formula: C29H34ClFN4O5. Mole weight: 573.06. | |
| CB6OCB | CB6OCB is a nonsymmetric liquid crystal dimer. Alternative Names: 1-(4-cyanobiphenyl-4'-yloxy)-6-(4-cyanobiphenyl-4'-yl)hexane; 4'-((6-(4'-cyano-[1,1'-biphenyl]-4-yl)hexyl)oxy)-[1,1'-biphenyl]-4-carbonitrile; 4,4''-(1,6-Hexanediyloxy)bis(biphenyl-4'-carbonitrile); [1,1'-Biphenyl]-4-carbonitrile, 4'-[[6-(4'-cyano[1,1'-biphenyl]-4-yl)hexyl]oxy]-. CAS No. 1531588-29-0. Molecular formula: C32H28N2O. Mole weight: 456.59. | |
| CB7993113 | CB7993113 is a potent AHR antagonist, with an IC50 of 0.33 μM. CB7993113 directly binds AHR protein and blocks AHR nuclear translocation. CB7993113 inhibits polycyclic aromatic hydrocarbon (PAH)- and TCDD-induced reporter activity by 75% and 90% respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 819827-50-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-111450. | |
| CB7CB | CB7CB. Alternative Names: 4',4''-(1,7-Heptanediyl)bis[(biphenyl-4'-carbonitrile)]; 4',4'''-(Heptane-1,7-diyl)bis(([1,1'-biphenyl]-4-carbonitrile)). Grades: 95%. CAS No. 149430-73-9. Molecular formula: C33H30N2. Mole weight: 454.61. | |
| CB-839 | CB-839 an is orally bioavailable inhibitor of glutaminase, with potential antineoplastic activity. Upon oral administration, CB-839 selectively and irreversibly inhibits glutaminase, a mitochondrial enzyme that is essential for the conversion of the amino acid glutamine into glutamate. By blocking glutamine utilization, proliferation in rapidly growing cells is impaired. Glutamine-dependent tumors rely on the conversion of exogenous glutamine into glutamate and glutamate metabolites to both provide energy and generate building blocks for the production of macromolecules, which are needed for cellular growth and survival. Check for active clinical trials or closed clinical trials using this agent. (NCI Thesaurus). ( ). Alternative Names: CB-839; CB839; CB 839. Grades: 98%. CAS No. 1439399-58-2. Molecular formula: C26H24F3N7O3S. Mole weight: 571.57. | |
| CBD-1 | CBD-1 is isolated from Canis lupus. It has antibacterial and antifungal activity. | |
| c-Bicyclo[2.2.1]hept-2-yl-methylamine hydrobromide | c-Bicyclo[2.2.1]hept-2-yl-methylamine hydrobromide. Alternative Names: 2-Aminomethylnorbornane; Norbornylmethylamine; 2-Aminomethyl-bicyclo<2,2,1>heptan; 2-Norbornanemethylamine. CAS No. 14370-50-4. Purity: 96%. Product ID: ACM14370504. Molecular formula: C8H16BrN. Mole weight: 206.13. IUPAC Name: 3-bicyclo[2.2.1]heptanylmethanamine. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| CBiPES | CBiPES is a potent mGlu2 positive allosteric modulator with an EC50 value of 92.8 nM. CBiPES attenuates stress-induced hyperthermia and Phencyclidine-induced hyperlocomotor activity. CBiPES can be used for research of neurological diseases, such as Parkinson's disease (PD)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 353235-01-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107505A. | |
| CBiPES hydrochloride | CBiPES hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 856702-40-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CBL0137 | CBL0137, a curaxin compound, is a histone chaperone facilitates chromatin transcription (FACT) inhibitor. CBL0137 downregulates NF-κB and activates p53. CBL0137 restores both histone H3 acetylation and trimethylation. CBL0137 is an anticancer agent. CBL0137 induces cancer cell apoptosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Curaxin 137; CBL-C137. CAS No. 1197996-80-7. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18935. | |
| CBL0137 | CBL0137 is a metabolically stable curaxin that activates p53 with an EC50 value of 0.37 μM and inhibits NF-κB with an EC50 of 0.47 μM. It also inhibits histone chaperone FACT (facilitates chromatin transcription) and MYC signal. Alternative Names: CBL0137; CBL-0137; CBL 0137; CBLC137; CBLC-137; CBLC 137; Curaxin 137; 1,1'-(9-(2-(Isopropylamino)ethyl)-9H-carbazole-3,6-diyl)diethanone; 1-[6-acetyl-9-[2-(propan-2-ylamino)ethyl]carbazol-3-yl]ethanone. CAS No. 1197996-80-7. Molecular formula: C21H24N2O2. Mole weight: 336.435. | |
| CBL0137 hydrochloride | NF-κB (nuclear factor kappa-light-chain-enhancer of activated B cells) is a protein complex that controls transcription of DNA, cytokine production and cell survival. CBL0137 activates p53 and inhibits NF-kB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It functionally inactivates the facilitates chromatin transcription complex, driving the effects on p53 and NF-κB and promoting cancer cell death. Alternative Names: CBLC137; CBL-0137; Curaxin 137. Grades: ≥98%. CAS No. 1197397-89-9. Molecular formula: C21H24N2O2·HCl. Mole weight: 372.9. | |
| CBL0137 hydrochloride | CBL0137 hydrochloride is an inhibitor of the histone chaperone, FACT. CBL0137 hydrochloride can also activate p53 and inhibits NF-κB with EC50s of 0.37 and 0.47 μM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Curaxin-137 hydrochloride; CBL-C137 hydrochloride. CAS No. 1197397-89-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18935A. | |
| CBL0137 Hydrochloride | CBL0137 (CBLC137, Curaxin 137) HCl activates p53 and inhibits NF-κB with EC50s of 0.37 μM and 0.47 μM in the cell-based p53 and NF-kB reporter assays, respectively. It also inhibits histone chaperone FACT (facilitates chromatin transcription complex). Group: Inhibitors. Alternative Names: CBLC137 HCl, Curaxin 137 HCl. CAS No. 1197397-89-9. Pack Sizes: 5mg. Product ID: S8483. Formula: C21H24N2O2.HCl. Smiles: CC(C)NCCN1C2=C(C=C(C=C2)C(=O)C)C3=C1C=CC(=C3)C(=O)C.Cl. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Cbl-b-IN-1 | Cbl-b-IN-1 (Example 519) is an inhibitor of Cbl-b, with an IC50 of less than 100 nM. Cbl-b-IN-1 can promote the secretion of cytokines such as IL-2, IFN-γ, and TNF-α, facilitate T cell activation, and enhance the TCR signaling pathway. Cbl-b-IN-1 can be used in research on immunomodulation[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2368841-84-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-136339. | |
| Cbl-b-IN-10 | Cbl-b-IN-10 is a Cbl-b and c-Cbl inhibitor with IC50 values of 6.0 nM and 3.5 nM, respectively. Cbl-b-IN-10 can be used in the study of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2815225-12-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156766. | |
| Cbl-b-IN-5 | Cbl-b-IN-5 (compound 6) is a Cbl-b inhibitor (IC50=3-10 μM). Cbl-b-IN-5 has the potential to be used in the study of cancer and related diseases amenable to immune system modulation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2368835-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155120. | |
| Cbl-b-IN-9 | Cbl-b-IN-9 (Compound 300) is a casitas B-lineage lymphoma-b (Cbl-b) and c-Cbl inhibitor with IC50s of 5.6 nM and 4.7 nM, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2815223-41-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156765. | |
| CBM 301940 | Malonyl-CoA decarboxylase (MCD) is found from bacteria to humans, which has important roles in regulating fatty acid metabolism and food intake. CBM 301940 is a potent malonyl-CoA decarboxylase (MCD) inhibitor with IC50 of 23 nM. It suppresses malonyl-CoA degradation and fatty acid oxidation in isolated rat hearts, leading to secondary increase in glucose oxidation. Alternative Names: (2S,3R,4S)-3-ethenyl-2-(beta-D-glucopyranosyloxy)-3,4-dihydro-4-(2-oxoethyl)-2H-pyran-5-carboxylic acid, methyl ester; CBM301940; CBM-301940. Grades: ≥98%. CAS No. 902146-11-6. Molecular formula: C15H20F6N2O5. Mole weight: 422.32. | |
| CBP501 Affinity Peptide | CBP501 Affinity Peptide exhibits similarity to part of the human 14-3-3e αC helix, suggesting that CBP501 may bind to this region. Alternative Names: H-Asn-Ser-Asp-Cys-Ile-Ile-Ser-Arg-Lys-Ile-Glu-Gln-Lys-Glu-OH; L-Glutamic acid, L-asparaginyl-L-seryl-L-α-aspartyl-L-cysteinyl-L-isoleucyl-L-isoleucyl-L-seryl-L-arginyl-L-lysyl-L-isoleucyl-L-α-glutamyl-L-glutaminyl-L-lysyl-. Grades: ≥95%. CAS No. 1351804-17-5. Molecular formula: C68H119N21O25S. Mole weight: 1662.89. | |
| CBPD-268 | CBPD-268 is a potent and orally active CBP/p300 PROTAC degrader with an DC50 value of ≤ 0.03 nM. CBPD-268 induces CBP/p300 degradation and inhibits cell growth. CBPD-268 shows antitumor activity. CBPD-268 has the potential for the research of AR-positive prostate cancer (Structure Note: Red, Androgen receptor degrader (HY-W248665A); Blue, CBP/p300 ligand (HY-161483); Black, Linker)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2832961-58-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-161369. | |
| CBPD-409 | CBPD-409 is an orally active PROTAC degrader for CBP/p300, with DC50 of 0.2-0.4 nM. CBPD-409 exhibits antiproliferative effects in AR+ prostate cancer cell lines VCaP, LNCaP and 22Rv1, with IC50s of 1.2-2.0 nM. CBPD-409 exhibits antitumor efficacy (Red: CBP inhibitor GNE049 (HY-108435); Blue: CRBN/cullin 4A Thalidomide (HY-14658); Black: Linker)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3037549-86-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-158113. | |
| CBP/p300-IN-1 | CBP/p300-IN-1 is a CBP/EP300 bromodomain inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 2443789-32-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111420. | |
| CBP/p300-IN-8 | CBP/p300-IN-8 is a potent inhibitor of the CBP/P300 family of bromodomains. CBP/p300-IN-8 inhibits CBP (IC50=0.01-0.1 μΜ) and BRD4 (IC50=1-1000 μΜ) activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2304416-91-7. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-136920. | |
| CBP/p300 ligand 2 | CBP/p300 ligand 2 is a ligand for target protein for PROTAC of dCBP-1. dCBP-1 is a potent and selective heterobifunctional degrader of p300/CBP[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2484741-78-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138539. | |
| CBQCA Reagent | CBQCA Reagent is an amine-reactive fluorescent probe that can be used in electrophoretic or chromatographic methods. Alternative Names: CBQCA;3-(4-Carboxybenzoyl)-2-quinolinecarboxaldehyde; 3-(4-Carboxybenzoyl)quinoline-2-carboxaldehyde; 4-[(2-formylquinolin-3-yl)carbonyl]benzoic acid. CAS No. 131124-59-9. Molecular formula: C18H11NO4. Mole weight: 305.29. | |
| CBR-470-1 | CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2416095-06-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134205A. | |
| CBR-5884 | CBR-5884 is an active, selective inhibitor of phosphoglycerate dehydrogenase (PHGDH) with an IC50 of 33 μM. CBR-5884 inhibits de novo serine synthesis in cancer cells and is selectively toxic to cancer cell lines with high serine biosynthetic activity. CBR-5884 selectively inhibits the proliferation of melanoma and breast cancer lines that have a high propensity for serine synthesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 681159-27-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100012. | |
| CBS9106 | CBS9106, also known as BMS-566419, is a novel reversible oral CRM1 inhibitor with CRM1 degrading activity. CRM1 plays an important role in the nuclear export of cargo proteins bearing nuclear exporting signal sequences. CBS9106 inhibits CRM1-dependent nuclear export, causing arrest of the cell cycle and inducing apoptosis in a time- and dose-dependent manner for a broad spectrum of cancer cells, including multiple myeloma cells. CBS9106 reduces CRM1 protein levels significantly without affecting CRM1 mRNA expression. Oral administration of CBS9106 significantly suppresses tumor growth and prolongs survival in mice bearing tumor xenograft without a significant loss in body weight. A reduced level of CRM1 protein is also observed in tumor xenografts isolated from mice treated with CBS9106. Taken together, these results indicate that CBS9106 is a novel reversible CRM1 inhibitor and a promising clinical candidate. Alternative Names: SL-801; SL801; SL 801; CBS-9106; CBS 9106; BMS-566419; BMS566419; BMS 566419; 1H-Pyrrole-2,5-dione, 1-[[6-chloro-5-(trifluoromethyl)-2-pyridinyl]amino]-3-[(3,3-dimethylbutoxy)methyl]-4-methyl-. Grades: 98%. CAS No. 1076235-04-5. Molecular formula: C18H21ClF3N3O3. Mole weight: 419.83. | |
| c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm | c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-Agm is an effective and selective short-acting peptide V2 receptor (V2R) agonist. Alternative Names: D-Argininamide, 4-chloro-N-(4-mercapto-1-oxobutyl)-L-phenylalanyl-3-(2-thienyl)-L-alanyl-L-valyl-L-asparaginyl-L-cysteinyl-L-prolyl-N,N-diethyl-, cyclic (1→5)-thioether. CAS No. 1647119-71-8. Molecular formula: C47H69ClN12O9S2. Mole weight: 1045.71. | |
| c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 | c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 is an effective and selective short-acting peptide V2 receptor (V2R) agonist. Alternative Names: Velmupressin; L-Prolinamide, 4-chloro-N-(4-mercapto-1-oxobutyl)-L-phenylalanyl-3-(2-thienyl)-L-alanyl-L-valyl-L-asparaginyl-L-cysteinyl-N-(4-((aminoiminomethyl)amino)butyl)-, cyclic (1->5)-thioether. Grades: ≥98%. CAS No. 1647119-61-6. Molecular formula: C42H60ClN11O8S2. Mole weight: 946.58. | |
| c(Bua-Cpa-Thi-Val-Asn-Cys)-Pro-d-Arg-NEt2 acetate | It is a potent, selective and short-acting peptide V2 receptor (V2R) agonist. Alternative Names: 1-{[(3R,6S,9S,12S,15S)-6-(2-Amino-2-oxoethyl)-15-(4-chlorobenzyl)-9-isopropyl-5,8,11,14,17-pentaoxo-12-(2-thienylmethyl)-1-thia-4,7,10,13,16-pentaazacycloicosan-3-yl]carbonyl}-N-(4-carbamimidamidobutyl)-L-prolinamide acetate (1:1). Grades: ≥98%. CAS No. 1647120-04-4. Molecular formula: C44H64ClN11O10S2. Mole weight: 1006.63. | |
| Cbz-1-amino-1-cyclooctanecarboxylic acid | Cbz-1-amino-1-cyclooctanecarboxylic acid. Alternative Names: CBZ-1-AMINO-1-CYCLOOCTANECARBOXYLIC ACID. CAS No. 175407-63-3. Purity: 96%. Product ID: ACM175407633. Molecular formula: C17H23NO4. Mole weight: 305.37. IUPAC Name: 1-(phenylmethoxycarbonylamino)cyclooctane-1-carboxylate. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Cbz-1-amino-1-cyclopentanecarboxylic acid | Cbz-1-amino-1-cyclopentanecarboxylic acid. CAS No. 17191-44-5. Purity: 98%. Product ID: ACM17191445. Molecular formula: C14H17NO4. Mole weight: 263.29. Alfa Chemistry - ISO 9001:32057 Certified. | |
| CBZ-8-amino-3,6-dioxaoctanoic acid | CBZ-8-amino-3,6-dioxaoctanoic acid. CAS No. 16545-06-8. |  |
| CBZ-9-amino-4,7-dioxanonanoic acid | CBZ-9-amino-4,7-dioxanonanoic acid. CAS No. 462100-05-6. | |
| Cbz-Aib-Leu-OMe | Cbz-Aib-Leu-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the α-aminoisobutyric acid (Aib) residue, preventing unwanted reactions during synthesis. Aib is a non-natural amino acid that induces helical structures in peptides due to its steric properties. Leu (Leucine) is the second amino acid in the sequence, known for its hydrophobic character, contributing to the overall structure and stability of the peptide. The OMe (methyl ester) group at the C-terminus indicates that the carboxyl group is esterified, which can be useful in strategies where further peptide extension or specific cleavage is required. This compound is employed to introduce both structural constraints and hydrophobic properties into peptides, enhancing their desired functional characteristics. Alternative Names: N-Benzoxycarbonyl-alpha-methyl-alanyl-L-leucine methyl ester; Methyl (2-(((benzyloxy)carbonyl)amino)-2-methylpropanoyl)-L-leucinate; Z-Aib-Leu-OMe; L-Leucine, 2-methyl-N-[(phenylmethoxy)carbonyl]alanyl-, methyl ester; 2-Methyl-N-[(phenylmethoxy)carbonyl]alanyl-L-leucine methyl ester. Grades: ≥95%. CAS No. 866919-63-3. Molecular formula: C19H28N2O5. Mole weight: 364.44. | |
| Cbz-Asp(OtBu)-Phe-Glu(OtBu)-Glu(OtBu)-Ile-Pro-OH | Cbz-Asp(OtBu)-Phe-Glu(OtBu)-Glu(OtBu)-Ile-Pro-OH is a protected hexapeptide used in peptide synthesis. It consists of aspartic acid (Asp), phenylalanine (Phe), glutamic acid (Glu), isoleucine (Ile), and proline (Pro). The Cbz (Carbobenzyloxy) group protects the N-terminus of aspartic acid, while the OtBu (tert-butyl) groups protect the hydroxyl groups of the glutamic acid residues. The remaining amino acids are in their free forms, with the C-terminus of the proline residue indicated by -OH, allowing for further coupling or modifications. This hexapeptide is designed for controlled reactivity and stability during peptide synthesis. Alternative Names: Cbz-Asp(OtBu)-Phe-Glu(OtBu)-Glu(OtBu)-Ile-Pro; ((S)-2-((S)-2-((S)-2-((S)-2-(((Benzyloxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanamido)-3-phenylpropanamido)-5-(tert-butoxy)-5-oxopentanamido)-5-(tert-butoxy)-5-oxopentanoyl)-L-isoleucyl-L-proline; Cbz-Asp(tBu)-Phe-Glu(tBu)-Glu(tBu)-Ile-Pro-OH. Grades: ≥90%. Molecular formula: C54H78N6O15. Mole weight: 1051.25. | |
| Cbz-Asp(OtBu)-Phe-Glu(OtBu)-OH | Cbz-Asp(OtBu)-Phe-Glu(OtBu)-OH is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the aspartic acid (Asp) residue, preventing it from reacting during synthesis. Both the aspartic acid and glutamic acid (Glu) residues have their side chain carboxyl groups protected by OtBu (tert-butyl) groups, ensuring these groups remain unreactive until selective deprotection is required. Phe (Phenylalanine) is the central amino acid in the sequence, contributing aromatic character. The -OH at the C-terminus indicates a free carboxyl group, allowing for further peptide coupling. This compound is used to introduce aspartic acid, phenylalanine, and glutamic acid into peptides with specific protections to control the reactivity and maintain the integrity of functional groups during synthesis. Alternative Names: DFE; ((Benzyloxy)carbonyl)-O-(tert-butyl)-L-aspartyl-L-phenylalanyl-O-(tert-butyl)-L-glutamic acid; Z-Asp(OtBu)-Phe-Glu(OtBu)-OH. Grades: ≥95%. Molecular formula: C34H45N3O10. Mole weight: 655.75. | |
| Cbz-Asp(OtBu)-Phe-Glu(OtBu)-OMe | Cbz-Asp(OtBu)-Phe-Glu(OtBu)-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the aspartic acid (Asp) residue, preventing it from reacting during the synthesis process. Both the aspartic acid and glutamic acid (Glu) residues have their side chain carboxyl groups protected by OtBu (tert-butyl) groups, ensuring these groups remain unreactive until selective deprotection is required. Phe (Phenylalanine), the central amino acid in the sequence, adds hydrophobic and aromatic properties to the peptide. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the glutamic acid is esterified, which can be useful for further synthetic modifications or coupling reactions. This compound is employed to introduce aspartic acid, phenylalanine, and glutamic acid into peptides, with controlled reactivity through specific protective groups. Alternative Names: DFE; 5-(tert-Butyl) 1-methyl ((S)-2-(((benzyloxy)carbonyl)amino)-4-(tert-butoxy)-4-oxobutanoyl)-L-phenylalanyl-L-glutamate; Z-Asp(OtBu)-Phe-Glu(OtBu)-OMe. Grades: ≥95%. Molecular formula: C35H47N3O10. Mole weight: 669.77. | |
| Cbz-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OMe | Cbz-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the aspartic acid (Asp) residue, preventing it from participating in unwanted reactions. The side chains of aspartic acid, tyrosine (Tyr), and serine (Ser) are each protected by OtBu (tert-butyl) groups, which shield their carboxyl and hydroxyl groups from reactivity until selective deprotection is desired. Tyr contributes aromatic and hydrophobic properties to the peptide, while Ser adds additional functionality. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of serine is esterified, which can facilitate further chemical modifications or reactions. This compound is used to incorporate aspartic acid, tyrosine, and serine into peptides, with specific protections to ensure controlled synthesis and reactivity of functional groups. Alternative Names: DYS; Cbz-Asp(tBu)-Tyr(tBu)-Ser(tBu)-OMe; Z-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OMe; Methyl (5S,8S,11S)-5-(2-(tert-butoxy)-2-oxoethyl)-8-(4-(tert-butoxy)benzyl)-11-(tert-butoxymethyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oate. Grades: ≥95%. Molecular formula: C37H53N3O10. Mole weight: 699.84. | |
| Cbz-beta-amino-L-alanine tert-butyl ester hydrochloride | Cbz-beta-amino-L-alanine tert-butyl ester hydrochloride. Alternative Names: AKOS022181690, AK-62642, (S)-tert-Butyl 3-amino-2-(((benzyloxy)carbonyl)amino)propanoate hydrochloride, 174796-88-4. CAS No. 174796-88-4. Purity: 96%. Product ID: ACM174796884. Molecular formula: C15H23ClN2O4. Mole weight: 330.807120 [g/mol]. IUPAC Name: tert-butyl (2S)-3-amino-2-(phenylmethoxycarbonylamino)propanoate;hydrochloride. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Cbz-(boc)Lys-(boc)-lys-(boc)-lys-(boc)-lys-OH | Cbz-(boc)Lys-(boc)-lys-(boc)-lys-(boc)-lys-OH. Molecular formula: C52H88N8O15. Mole weight: 1065.32. | |
| Cbz-Cyclohexyl-L-glycine | A gylicine derivative used in the preparation of peptides as inhibitors of serine proteases, particularly hepatitis C virus NS3-NS4A protease. Group: Biochemicals. Alternative Names: (α S) -α - [ [ (Phenylmethoxy) carbonyl] amino] cyclohexaneacetic Acid; (S) -α - [ [ (phenylmethoxy) carbonyl] amino] cyclohexaneacetic Acid. Grades: Highly Purified. CAS No. 69901-75-3. Pack Sizes: 5g. US Biological Life Sciences. | Worldwide |
| Cbz-D-Ala-OMe | Cbz-D-Ala-OMe. Alternative Names: methyl N-[(benzyloxy)carbonyl]alaninate; (S)-methyl 2-(benzyloxycarbonylamino)propanoate. CAS No. 64562-95-4. Molecular formula: C12H15NO4. Mole weight: 237.25. | |
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