A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Cc-CATH3 is isolated from Coturnix coturnix. Cc-CATH3 is an avian antimicrobial peptide (AMP) with 29 amino acids in length containing a broad-spectrum antibacterial activity. Cc-CATH3 showed considerable reduction of cytotoxic activity compared to other avian cathelicidins, with average IC(50) values of 17.16 μm.
CCCP
CCCP. Group: Biochemicals. Grades: Purified. CAS No. 555-60-2. Pack Sizes: 500mg. US Biological Life Sciences.
Worldwide
CCCP
CCCP is an oxidative phosphorylation (OXPHOS) uncoupler. CCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Carbonyl cyanide 3-chlorophenylhydrazone; Carbonyl Cyanide m-Chlorophenylhydrazone. CAS No. 555-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-100941.
CCCP (Carbonyl cyanide 3-chlorophenylhydrazone)
CCCP (Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone), an oxidative phosphorylation inhibitor, is a protonophore mitochondrial uncoupler that increases membrane permeability to protons, leading to a disruption in the mitochondrial membrane potential. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), the protonophore, can inhibits STING-mediated IFN-β production via disrupting mitochondrial membrane potential (MMP). Group: Inhibitors. Alternative Names: Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone. CAS No. 555-60-2. Pack Sizes: 25mg. Product ID: S6494. Formula: C9H5ClN4. Smiles: C1=CC(=CC(=C1)Cl)NN=C(C#N)C#N. Storage Conditions: 3 years -20°C powder.
United States; Europe
CCCP (Standard)
CCCP (Standard) is the analytical standard of CCCP. This product is intended for research and analytical applications. CCCP is an oxidative phosphorylation (OXPHOS) uncoupler. CCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Carbonyl cyanide 3-chlorophenylhydrazone (Standard); Carbonyl Cyanide m-Chlorophenylhydrazone (Standard). CAS No. 555-60-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100941R.
ccc_R08
ccc_R08 is a non-cytotoxic and orally active cccDNA inhibitor that reduces cccDNA levels in the liver of HBV-infected mice. ccc_R08 can be used in the study of HBV virus (hepatitis B virus) infection[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2919019-72-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148560.
CcD1
CcD1 is isolated from Capsicum chinense. It has antifungal activity.
CCF2-AM
CCF2-AM is a fluorescence resonance energy transfer (FRET) substrate consisting of a hydroxycoumarin donor conjugated to a fluorescein acceptor via a β-lactam ring.
CCF4-AM
CCF4-AM is a fluorescence resonance energy transfer (FRET) substrate consisting of a cephalosporin core connecting 7-hydroxycoumarin to fluorescein.
CCF642
CCF642 is a potent protein disulfide isomerases (PDI) inhibitor with an IC50 of 2.9 μM. CCF642 causes acute endoplasmic reticulum (ER) stress in multiple myeloma cells accompanied by apoptosis-inducing calcium release. CCF642 has broad anti-multiple myeloma activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 346640-08-2. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100430.
CCG 1423
CCG 1423. Group: Biochemicals. Grades: Purified. CAS No. 285986-88-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCG-1423
CCG-1423 is an inhibitor of Rho/MRTF/SRF pathway. CCG-1423 shows activities in several cancer cells. CCG-1423 is a promising lead compound for the development of novel pharmacologic tools, and it can be used for the research of cancer and diabetes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 285986-88-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13991.
CCG 203769
CCG 203769 is a selective G protein signaling (RGS4) inhibitor, which blocks the RGS4-Gαo protein-protein interaction in vitro with an IC50 of 17 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 410074-60-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00431.
CCG 203971
CCG 203971. Group: Biochemicals. Grades: Purified. CAS No. 1443437-74-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCG-203971
CCG-203971 is a second-generation Rho/MRTF/SRF pathway inhibitor. CCG-203971 potently targets RhoA/C-activated SRE-luciferase (IC50 =6.4 μM). CCG-203971 inhibits PC-3 cell migration with an IC50 of 4.2 μM. Potential anti-metastasis Agent[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1443437-74-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108361.
CCG 2046
CCG 2046. Group: Biochemicals. Grades: Purified. CAS No. 13017-69-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCG215022
CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1813527-81-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18991.
CCG-222740
CCG-222740 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor[1]. CCG-222740 is also a potent inhibitor of alpha-smooth muscle actin protein expression. CCG-222740 effectively reduces fibrosis in skin and blocks melanoma metastasis[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1922098-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121750.
CCG-232601
CCG-232601 (compound 8f) is a potent and orally active Rho/MRTF/SRF transcriptional pathway inhibitor. CCG-232601 inhibits the development of Bleomycin-induced dermal fibrosis in mice. CCG-232601 has the potential for the research of antifibrotic for systemic scleroderma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1922099-21-5. Pack Sizes: 1 mg. Product ID: HY-111432.
CCG273441
CCG273441 is a covalent inhibitor of G protein-coupled receptor (GPCR) kinase 5 (GRK5) with an IC50 value of 3.8 nM. CCG273441 is highly selective to GRK5 over GRK2 (IC50=4.8 μM) by binding Cys474, a GRK5 subfamily-specific residue, as a covalent handle[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2750414-35-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-47573.
CCG 50014
CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM, exhibiting >20-fold selectivity over other RGS proteins. Alternative Names: CCG50014; CCG-50014; 4-(4-fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione. Grades: >98%. CAS No. 883050-24-6. Molecular formula: C16H13FN2O2S. Mole weight: 316.35.
CCG 50014
CCG 50014. Group: Biochemicals. Grades: Purified. CAS No. 883050-24-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCG-50014
CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is >20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site[1]. CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 883050-24-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13509.
CCG 63802
CCG 63802. Group: Biochemicals. Grades: Purified. CAS No. 620112-78-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
Cc-GRP
Cc-GRP is a peptide with a molecular weight of 7kDa and it was observed to display homology to GRPs. Cc-GRP has antifungal activity.
CCHa2
CCHa2. Alternative Names: H-Gly-Cys-Gln-Ala-Tyr-Gly-His-Val-Cys-Tyr-Gly-Gly-His-NH2. Molecular formula: C57H79N19O16S2. Mole weight: 1350.48.
Cci I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme about 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. T↑CATGA AGTAC↓T. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Curtobacterium citreus. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1094RE.
CciN I
One unit of the enzyme is the amount required to hydrolyze 1 μg of Adenovirus-2 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GC↑GGCCGC CGCCGG↓CG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Curtobacterium citreus N. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Store at -20°C. Cat No: ET-1095RE.
CCK-4 Acetate
Tetragastrin is a tetrapeptide. Alternative Names: CCK-4; CCK4; CCK 4; Gastrin Tetrapeptide; Cholecystokinin Octapeptide (5-8); Cholecystokinin Tetrapeptide; Gastrin (14-17) (human). CAS No. 35144-91-3. Molecular formula: C29H36N6O6S. Mole weight: 596.70.
CCKBR agonist-1
CCKBR agonist-1 (Compound 3r1) is a Gq-protein-preferring cholecystokinin B receptor (CCKBR) agonist with an EC50 of 35 pM. CCKBR agonist-1 significantly increases the survival rate of neurons, with an EC50 of 37 pM. CCKBR agonist-1 can improve the cognitive decline in mice by upregulating α-secretase (ADAM10) and calcium signaling molecule PLCB4, reduce the number of amyloid β (Aβ) plaques, and promote long-term potentiation (LTP). CCKBR agonist-1 can be used for the study of Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2923120-30-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P11540.
CCK Octapeptide (non-sulfated)
Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK Octapeptide (non-sulfated) is the non-sulfated form of the C-terminal octapeptide of CCK. Alternative Names: CCK-8 (desulfated); Cholecystokinin (CCK) (26-33); 2-desulfo-cholecystokinin-8 (swine). Grades: 98%. CAS No. 25679-24-7. Molecular formula: C49H62N10O13S2. Mole weight: 1063.
CCL27
CCL27 is a chemotactic factor that attracts skin-associated memory T-lymphocytes. It may play a role in mediating homing of lymphocytes to cutaneous sites. Alternative Names: C-C Motif Chemokine Ligand 27.
Cc-LTP1
Cc-LTP1 is produced by Coffea canephora. It has active antifungal activity against Candida albicans.
CCM Alloy Powder
CCM is a non-magnetic, cobalt-chromium molybdenum alloy exhibiting high strength, corrosion resistance, wear resistance, and excellent biocompatibility. CCM alloy powder is produced by vacuum induction melting (VIM) followed by nitrogen gas atomization. It has excellent weldability in laser additive manufacturing processes and can be processed with either nitrogen or argon shielding gas.
CCMI
CCMI. Group: Biochemicals. Grades: Purified. CAS No. 917837-54-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
cCMP
cCMP, an intriguing cyclic cytidine monophosphate compound extensively utilized in the realm of biomedical research, has emerged as an invaluable protagonist. Affiliated with the intricacies of various signaling pathways, it conveniently serves as a second messenger, facilitating a comprehensive comprehension of cCMP's involvement in pivotal cellular functions. In the realm of immunology, its versatile nature enables it to diligently modulate the immune response, thus exhibiting promising potential in the battle against inflammatory diseases and cancerous afflictions. Alternative Names: Cytidine- 3', 5'- cyclic monophosphate, sodium salt. Grades: ≥ 98% by HPLC. CAS No. 54925-33-6. Molecular formula: C9H11N3O7P · Na. Mole weight: 327.2.
cCMP-AM
cCMP-AM is a membrane-permeant and metabolically activatable prodrug of cCMP, the potential further second messenger. cCMP is released after permeation and metabolism of cCMP-AM by esterases, which is trapped inside the cell and metabolized to result in a pulse-type signal. Alternative Names: Cytidine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grades: ≥ 95% by HPLC. Molecular formula: C12H16N3O9P. Mole weight: 377.2.
CCMV Gag-(7-25)
It is a cell penetrating peptide. Alternative Names: H-Lys-Leu-Thr-Arg-Ala-Gln-Arg-Arg-Ala-Ala-Ala-Arg-Lys-Asn-Lys-Arg-Asn-Thr-Arg-OH; L-lysyl-L-leucyl-L-threonyl-L-arginyl-L-alanyl-L-glutaminyl-L-arginyl-L-arginyl-L-alanyl-L-alanyl-L-alanyl-L-arginyl-L-lysyl-L-asparagyl-L-lysyl-L-arginyl-L-asparagyl-L-threonyl-L-arginine. Grades: ≥95%. Molecular formula: C93H175N43O25. Mole weight: 2295.70.
CCPA
CCPA (2-Chloro-N6-cyclopentyladenosine) a highly selective A1 adenosine receptors agonist with a Ki of 0.4 nM. CCPA inhibits adenylate cyclase with an IC50 of 33 nM. CCPA exhibits anti-seizure and cardiacprotective activity. CCPA can be used for the research of seizure and myocardial infarction[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Chloro-N6-cyclopentyladenosine. CAS No. 37739-05-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103185.
CCP peptide TFA
CCP peptide TFA is a synthetic cyclic citrullinated peptide that can be used as the substrate for detecting anti-CCP antibodies serologically. Alternative Names: His-Gln-Cys-His-Gln-Glu-Ser-Thr-{Cit}-Gly-Arg-Ser-Arg-Gly-Arg-Cys-Gly-Arg-Ser-Gly-Ser (Disulfide bridge: Cys3-Cys16). Grades: 95%. Molecular formula: C89H146N41F3O34S2. Mole weight: 2455.49.
CC-preferring endodeoxyribonuclease
Prefers CC sites in double-stranded circular and linear DNA. Greater affinity for double-stranded than single-stranded DNA. Produces nicks, generating double-stranded fragments with 5'- and/or 3'-protruding single-stranded tails. Requires magnesium ions for activity. The endonuclease from Chlorella-like green algae infected with NYs-1 virus 4 may be the same enzyme. Group: Enzymes. Synonyms: Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease. Enzyme Commission Number: EC 3.1.21.6. CAS No. 37211-67-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3576; CC-preferring endodeoxyribonuclease; EC 3.1.21.6; 37211-67-9; Streptomyces glaucescens exocytoplasmic dodeoxyribonuclease. Cat No: EXWM-3576.
CCR2-RA-[R]
CCR2-RA-[R] is an allosteric antagonist of the C-C chemokine receptor type 2 (CCR2) with an IC50 of 103 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 512177-83-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50081.
CCR4-351 hydrochloride
CCR4-351 hydrochloride is an orally active, potent and selective CCR4 antagonist. CCR4-351 hydrochloride, featuring a novel piperidinyl-azetidine motif, has IC50s of 22 nM and 50 nM in the calcium flux and CTX assay. CCR4-351 hydrochloride has antitumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2174938-71-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-131349A.
CCR4 antagonist 3
CCR4 antagonist 3 is a potent chemokine receptor 4 (CCR4) antagonist with an IC50 value of 1.7 μM for [125I]TARC (thymus and activation regulated chemokine). CCR4 antagonist 3 inhibits binding of radiolabeled TARC and macrophage-derived chemokine (MDC) to CCR4 receptors on the surface of CEM cells. CCR4 antagonist 3 also inhibits the in vitro migration of CEM cells mediated by TARC (IC50 = 6.4 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1957-1-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-147385.
CCR4 antagonist 4
CCR4 antagonist 4 (compound 22) is a selective and potent antagonist of the CC chemokine receptor-4 (CCR4), with an IC50 of 0.02 μM. CCR4 antagonist 4 also blocks MDC-mediated chemotaxis (IC50: 0.007 μM) and Ca2+ mobilization (IC50: 0.003 μM). CCR4 antagonist 4 can be used for allergic inflammation research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 668980-17-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157453.
CCR6 antagonist 1
CCR6 antagonist 1 is a CCR6 antagonist that inhibits the CCL20/CCR6 axis. CCR6 antagonist 1 can be used in the research of autoimmune-mediated inflammatory diseases, such as inflammatory bowel diseases (IBDs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 588674-64-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-151435.
CCR6 inhibitor 1
CCR6 inhibitor 1 is a potent and selective CCR6 inhibitor, with IC50s of 0.45 and 6 nM for monkey and human CCR6, much more selective at CCR6 over human CCR1 (IC50, > 30000 nM), and CCR7 (IC50, 9400 nM). CCR6 inhibitor 1 markedly blocks ERK phosphorylation. CCR6 inhibitor 1 is used in the research of autoimmune diseases and cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2437547-04-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112701.
CCR7 Ligand 1
CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric Ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. CCR7 Ligand 1, thiadiazole-dioxide ligan, suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CCR7-Cmp2105. CAS No. 681514-83-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-133073.
CCT018159
CCT018159 is an ATP-competitive HSP90β inhibitor, with an IC50 of 3.2 μM against human HSP90β ATPase and 6.6 μM against yeast HSP90β ATPase. CCT018159 induces cell cycle arrest and apoptosis in tumor cells, and inhibits invasion and angiogenesis. CCT018159 is applicable to cancer-related research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 171009-07-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-110042.
CCT 018159
CCT 018159. Group: Biochemicals. Grades: Purified. CAS No. 171009-07-7. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCT020312
CCT020312 is a selective EIF2AK3/PERK activator. CCT020312 elicits EIF2A phosphorylation in cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 324759-76-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119240.
CCT 031374 hydrobromide
CCT 031374 hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 1219184-91-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
CCT036477
CCT036477 is a Wnt/β-catenin pathway inhibitor. CCT036477 blocks transcription at β-catenin without altering its levels. CCT036477 inhibits proliferation of various cancer cells, development of embryos, and expression of Wnt target genes (PPARδ, Cyclin D1, TCF4, and ID2)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 305372-78-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-119966.
CCT128930
CCT128930 is a ATP-competitive and selective inhibitor of AKT (IC50=6 nM for AKT2). CCT128930 has 28-fold selectivity over the closely related PKA kinase (IC50=168 nM) through the targeting of Met282 of AKT (Met173 of PKA-AKT chimera), as well as 20-fold selectivity over p70S6K (IC50=120 nM). Antitumor activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 885499-61-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-13260.
CCT129957
CCT129957 is an indole derivative and a potent phospholipase C-γ (PLC-γ) inhibitor with an IC50 of ~3 μM and a GC50 of 15 μM. CCT129957 inhibits Ca2+ release in squamous carcinoma cells at ~15 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 883098-58-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111208.
CCT 137690
CCT 137690 is a potent and orally available aurora kinase inhibitor with IC50s of 15, 25, and 19 nM for aurora A, B and C, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1095382-05-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10804.
CCT241533 hydrochloride
CCT241533 hydrochloride is a potent and selective CHK2 inhibitor with an IC50 of 3 nM and a Ki of 1.16 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1431697-96-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14715B.
CCT245737
CCT245737 (SRA737) is an orally active and seletive Chk1 inhibitor, with an IC50 of 1.3 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SRA737. CAS No. 1489389-18-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18958.
CCT251545
CCT251545 is an orally bioavailable and potent inhibitor of WNT signaling with an IC50 of 5 nM in 7dF3 cells[1]. CCT251545 is a selective chemical probe for exploring the role of CDK8 and CDK19 in human disease[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1661839-45-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12681.
CCT-251921
CCT-251921 is a potent, selective, and orally bioavailable CDK8 inhibitor with an IC50 of 2.3 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1607837-31-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19984.
CCT365623 hydrochloride
CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor, with an IC50 of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2126136-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124674A.
CCT373566
CCT373566 is a potent and orally active molecular glue degrader of transcriptional repressor BCL6, with an IC50 of 2.2 nM. CCT373566 shows strong antiproliferative efficacy in vitro and reduction in tumor growth in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2378853-66-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-146185.
C Cushion Polyethylene Packaging Profile
Ideal for use on any type of glass, frames, appliances, furniture, glass windows, and more, our C cushion polyethylene packaging profiles are the perfect solution for all your shipping and transport needs. This reliable solution offers protection against bumps, nicks, scratches, and total breakage by absorbing impacts and vibrations to absorb the brunt of the forces associated with moving an item from one place to the next.
CCW16
CCW16 is a cofactor for the synthesis of protein degraders, such as PROTACs CCW 28-3 (HY-156774). Uses: Scientific research. Category: Signaling pathways. CAS No. 2361138-33-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143346.
CCW 28-3
CCW 28-3 is a PROTAC-based BRD4 degrader in a proteasome- and RNF4-dependent manner (Pink: JQ-1 (carboxylic acid) (HY-78695); Black: linker (HY-170384); Blue: RNF4 ligand CCW16 (HY-143346))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361142-23-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156774.
C-Cys-Mel
C-Cys-Mel. Alternative Names: Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-Cys.
CD00509
CD00509 is a tyrosyl-DNA phosphodiesterase (PDE) Tdp1 inhibitor with an IC50 of 0.71 μM. CD00509 increases DNA damage and promotes apoptosis of MCF-7 cells. CD00509 can sensitize breast cancer cells and wild-type murine embryonic fibroblasts (MEFs) to Camptothecin (CPT) (HY-16560). CD00509 can be used for the study of cancers such as breast cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 27430-18-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W177546.
CD1530
CD1530 is an orally active, selective RARγ agonist and antibacterial agent. CD1530 reduces Smad1/5/8 phosphorylation and overall Smad levels. CD1530 reduces β-catenin, MMP9 protein, and ROS levels. CD1530 exhibits activities such as inhibiting heterotopic ossification, promoting Achilles tendon healing, and inhibiting muscle fatty infiltration. CD1530 can be used in the research of orthopedic diseases (such as heterotopic ossification, Achilles tendon injury), muscle diseases (such as muscle fatty infiltration-related diseases)[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 107430-66-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108527.
CD 1530
CD 1530. Group: Biochemicals. Grades: Purified. CAS No. 107430-66-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.