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| Product | Description | |
|---|---|---|
| Cbz-Ile-Aib-Leu-OH | Cbz-Ile-Aib-Leu-OH is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the isoleucine (Ile) residue, preventing it from reacting during synthesis. Aib (α-aminoisobutyric acid), a non-natural amino acid known for inducing helical structures, follows isoleucine. Leu (Leucine), the final amino acid in the sequence, adds hydrophobic properties. The -OH at the C-terminus indicates a free carboxyl group, allowing for further peptide coupling or modifications. This compound is used to introduce isoleucine, Aib, and leucine into peptides while controlling the reactivity of their functional groups through selective protection. Synonyms: IXL; (2-((2S,3S)-2-(((Benzyloxy)carbonyl)amino)-3-methylpentanamido)-2-methylpropanoyl)-L-leucine; Z-Ile-Aib-Leu-OH. Grade: ≥95%. Molecular formula: C24H37N3O6. Mole weight: 463.58. |  |
| Cbz-L-tyrosine benzyl ester triflate | Cbz-L-tyrosine benzyl ester triflate. Alternative Names: ACMC-209ekd, 183070-41-9. CAS No. 183070-41-9. Purity: 96%. Product ID: ACM183070419. Molecular formula: C25H22F3NO7S. Mole weight: 537.5. IUPAC Name: benzyl 3-(4-hydroxyphenyl)-2-(phenylmethoxycarbonylamino)propanoate;trifluoromethanesulfonic acid. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Cbz-L-Aspartic 4-tert-butyl ester | Cbz-L-Aspartic 4-tert-butyl ester. Group: Biochemicals. Grades: Highly Purified. CAS No. 5545-52-8. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C16H21NO6. US Biological Life Sciences. |  Worldwide |
| Cbz-L-β-homoAsp(otBu)-OH | Cbz-L-β-homoAsp(otBu)-OH. CAS No. 83436-45-7. Molecular formula: C17H23NO6. Mole weight: 337.4. | |
| Cbz-L-glutamine | Cbz-L-glutamine. Group: Biochemicals. Grades: Highly Purified. CAS No. 2650-64-8. Pack Sizes: 100g, 250g, 500g, 1kg, 2kg. US Biological Life Sciences. | Worldwide |
| Cbz-L-hydroxyproline | Cbz-L-hydroxyproline. Group: Biochemicals. Grades: Highly Purified. CAS No. 13504-85-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. US Biological Life Sciences. | Worldwide |
| Cbz-L-Isoleucine dicyclohexylamine salt | Cbz-L-Isoleucine dicyclohexylamine salt. Group: Biochemicals. Grades: Highly Purified. CAS No. 26699-00-3. Pack Sizes: 50g, 100g, 250g, 500g, 1Kg. Molecular Formula: C26H42N2O4. US Biological Life Sciences. | Worldwide |
| Cbz-L-(+)-Phenylglycine | Cbz-L-(+)-Phenylglycine. Group: Biochemicals. Grades: Highly Purified. CAS No. 53990-33-3. Pack Sizes: 50g, 100g. US Biological Life Sciences. | Worldwide |
| Cbz-L-pyroglutamic acid | Cbz-L-pyroglutamic acid. Group: Biochemicals. Grades: Highly Purified. CAS No. 32159-21-0. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C13H13NO5. US Biological Life Sciences. | Worldwide |
| Cbz-L-tert-Leucine | Leucine derivative used in the preparation of various pharmaceutical agents such as TRPV4 antagonists, HIV-1 protease inhibitors and serine protease inhibitors. Group: Biochemicals. Alternative Names: 3-Methyl-N-[ (phenylmethoxy) carbonyl]-L-valine; N-Carbobenzoxy-(S)-tert-leucine; 2S-Benzyloxycarbonylamino-3,3-dimethylbutyric Acid; Z-L-tert-Leucine; Benzyloxycarbonyl-L-tert-leucine; N-(Benzyloxycarbonyl)-L-tert-butylglycine; N-Benzyloxycarbonyl-L-tert-leucine; N-Benzyloxycarbonyl-tert-leucine. Grades: Highly Purified. CAS No. 62965-10-0. Pack Sizes: 2.5g. US Biological Life Sciences. | Worldwide |
| Cbz-Lys(Boc)-OH | Cbz-Lys(Boc)-OH is a protected amino acid, primarily utilized in peptide synthesis, protein engineering, and drug development, particularly in research involving lysine residues[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2389-60-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 g; 10 g; 25 g; 50 g; 100 g. Product ID: HY-W009033. |  |
| Cbz-MeGly(heptene)-OH | Cbz-MeGly(heptene)-OH is a protected amino acid derivative used in peptide synthesis. The Cbz (carbobenzyloxy) group serves as a protective group for the amino terminus, preventing unwanted reactions during synthesis. MeGly refers to N-methylglycine, a simple amino acid derivative, and (heptene) indicates the presence of a heptene moiety, likely modifying the side chain for added hydrophobicity or reactivity. This compound is useful in creating modified peptides with specific structural or functional properties. Synonyms: Z-MeGly(heptene)-OH. Grade: ≥95%. Molecular formula: C16H21NO4. Mole weight: 291.35. | |
| Cbz-N-amido-PEG6-acid | Cbz-N-amido-PEG6-acid. CAS No. 1334177-80-8. Purity: 95%+. Product ID: ACM1334177808. Molecular formula: C23H37NO10. Mole weight: 487.24. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Cbz-neuraminic acid | Cbz-neuraminic acid. Alternative Names: CBZ-NEURAMINIC ACID. CAS No. 17367-66-7. Purity: 96%. Product ID: ACM17367667. Molecular formula: C17H23NO10. Mole weight: 401.37. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Cbz-N-Me-D-Leu-OH | Cbz-N-Me-D-Leu-OH. Synonyms: Cbz-N-methyl-D-leucine; (R)-2-(((Benzyloxy)carbonyl)(methyl)amino)-4-methylpentanoic acid; Benzyloxycarbonyl-N-alpha-methyl-D-leucine. CAS No. 65635-85-0. Molecular formula: C15H21NO4. Mole weight: 279.33. | |
| Cbz-N-methyl-L-valine | Cbz-N-methyl-L-valine is an N-protected and N-methylated derivative of L-valine, featuring a carbobenzyloxy group on the secondary amine. Applications: It is commonly used in the synthesis of cyclosporine analogs and other n-methylated cyclic peptides known for high oral bioavailability and stability. Category: Intermediates. Synonyms: N-Cbz-N-methyl-L-valine;3-methyl-2-[methyl(phenylmethoxycarbonyl)amino]butanoic acid;(S)-2-((benzyloxycarbonyl)(methyl)amino)-3-methylbutanoic acid;(2S)-2-[[(benzyloxy)carbonyl](Methyl)aMino]-3-Methylbutanoic acid;(S)-N-(Benzyloxycarbonyl)-N-Methylvaline. CAS No. 42417-65-2. Product ID: INT42417652. Molecular formula: C14H19NO4. Mole weight: 265.3. InChIKey: NNEHOKZDWLJKHP-LBPRGKRZSA-N. Appearance: White powder. |  |
| Cbz-Phe-Gly-Oet-OH | Cbz-Phe-Gly-Oet-OH. Synonyms: Ethyl ((benzyloxy)carbonyl)-L-phenylalanylglycinate; N-Carbobenzyloxy-phenylalanylglycine ethyl ester. CAS No. 2778-34-9. Molecular formula: C21H24N2O5. Mole weight: 384.43. | |
| Cbz-Phe-Thr(tBu)-OMe | Cbz-Phe-Thr(tBu)-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the phenylalanine (Phe) residue, preventing it from participating in unwanted reactions during the synthesis. The Thr (Threonine) residue is protected at its hydroxyl side chain by a tBu (tert-butyl) group, safeguarding this functional group until selective deprotection is needed. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group is esterified, which can be useful in certain synthetic strategies to prevent reactions at the carboxyl end. This compound is used to introduce phenylalanine and threonine into peptides while maintaining control over the reactivity of the functional groups. Synonyms: Methyl N-(((benzyloxy)carbonyl)-L-phenylalanyl)-O-(tert-butyl)-L-threoninate; Z-Phe-Thr(tBu)-OMe; FT; L-Threonine, O-(1,1-dimethylethyl)-N-[N-[(phenylmethoxy)carbonyl]-L-phenylalanyl]-, methyl ester; Cbz-Phe-Thr(OtBu)-OMe. Grade: ≥95%. Molecular formula: C26H34N2O6. Mole weight: 470.57. | |
| Cbz-Pro-Ala-NH2 | Cbz-Pro-Ala-NH2 is a protected dipeptide derivative used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the proline (Pro) residue, preventing it from participating in unwanted reactions during the peptide synthesis process. Ala (Alanine) is the second amino acid in the sequence, and the -NH2 indicates a free amino group at the C-terminus of alanine, allowing for further peptide coupling or modification. This compound is used to introduce proline and alanine into peptides while controlling the reactivity of the functional groups through selective protection. Synonyms: Z-Pro-Ala-NH2; PA. Grade: ≥95%. Molecular formula: C16H21N3O4. Mole weight: 319.36. | |
| Cbz-Pro-Pro-Ser(OtBu)-NH2 | Cbz-Pro-Pro-Ser(OtBu)-NH2 is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the proline (Pro) residue, preventing it from reacting during synthesis. The Pro-Pro sequence consists of two proline residues, known for their role in introducing kinks or turns in peptide chains. The side chain hydroxyl group of the serine (Ser) residue is protected by an OtBu (tert-butyl) group to prevent unwanted reactions until deprotection. The -NH2 at the C-terminus indicates a free amine group, allowing for further modifications or coupling reactions. This peptide is used to incorporate proline and serine into peptides, with specific protections to ensure controlled synthesis and functional group reactivity. Synonyms: PPS; Benzyl (S)-2-((S)-2-(((S)-1-amino-3-(tert-butoxy)-1-oxopropan-2-yl)carbamoyl)pyrrolidine-1-carbonyl)pyrrolidine-1-carboxylate; Z-Pro-Pro-Ser(OtBu)-NH2; Cbz-Pro-Pro-Ser(tBu)-NH2. Grade: ≥97%. Molecular formula: C25H36N4O6. Mole weight: 488.59. | |
| Cbz-Pyr-Gly-Arg-MCA | Cbz-Pyr-Gly-Arg-MCA is an inhibitor of protein interactions. It binds to the peptide receptor and blocks the activation of the receptor. Synonyms: L-Argininamide, 5-oxo-1-[(phenylmethoxy)carbonyl]-L-prolylglycyl-N-(4-methyl-2-oxo-2H-1-benzopyran-7-yl)-. CAS No. 113865-89-7. Molecular formula: C31H35N7O8. Mole weight: 633.65. | |
| Cbz-S-2-amino-Dodecanoic acid | Cbz-S-2-amino-Dodecanoic acid. CAS No. 134357-45-2. Product ID: ACM134357452. Molecular formula: C20H31NO4. Mole weight: 349.46444. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Cbz-Sar-Sar-OH | Cbz-Sar-Sar-OH is a peptide building block used in peptide synthesis. It features a Cbz (Carbobenzyloxy) protective group on the N-terminus, which prevents unwanted reactions during the peptide assembly process. The core structure includes two Sar (Sarcosine) residues, a small amino acid derivative with a methyl group replacing one hydrogen, which contributes to flexibility and hydrophobic interactions. The -OH at the C-terminus denotes a free carboxyl group, allowing for coupling with other amino acids. This compound is used to introduce specific dipeptide sequences into peptides, modifying their structural and functional properties. Synonyms: N-Benzoxycarbonyl-sarcosyl-sarcosine; N-[(Benzyloxy)carbonyl]-N-methylglycyl-N-methylglycine; N-(N-((Benzyloxy)carbonyl)-N-methylglycyl)-N-methylglycine; Z-Sar-Sar-OH. Grade: ≥95%. CAS No. 62245-96-9. Molecular formula: C14H18N2O5. Mole weight: 294.30. | |
| Cbz-Sar-Sar-Sar-Sar-OH | Cbz-Sar-Sar-Sar-Sar-OH is a protected tetrapeptide composed of four sarcosine (Sar) residues, a derivative of glycine with a methyl group on the nitrogen atom. The Cbz (Carbobenzyloxy) group protects the N-terminus of the first sarcosine residue, while the C-terminus of the final sarcosine residue is free, indicated by -OH, allowing for further coupling or modifications. This tetrapeptide is designed to introduce a flexible, non-chiral sequence into peptide chains, often used to modify the physical properties of the resulting peptide, such as increasing solubility or altering conformation. The protective groups ensure that the synthesis proceeds in a controlled and selective manner. Synonyms: 4,7,10,13-Tetramethyl-3,6,9,12-tetraoxo-1-phenyl-2-oxa-4,7,10,13-tetraazapentadecan-15-oic acid; Z-Sar-Sar-Sar-Sar-OH; Cbz-Sar-Sar-Sar-Sar. Grade: ≥95%. Molecular formula: C20H28N4O7. Mole weight: 436.47. | |
| Cbz-Ser(OtBu)-Asp(OtBu)-OMe | Cbz-Ser(OtBu)-Asp(OtBu)-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the serine (Ser) residue, preventing it from reacting during synthesis. The hydroxyl group on serine is protected by a tBu (tert-butyl) group, which shields it until deprotection is required. The Asp (Aspartic acid) residue also has its side chain protected by a tBu group, ensuring that the side chain carboxyl group remains unreactive. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the aspartic acid is esterified, which can facilitate further reactions or modifications. This compound is utilized to incorporate serine and aspartic acid into peptides, with specific protections in place to ensure controlled synthesis and functional modifications. Synonyms: SD; 4-(tert-Butyl) 1-methyl N-((benzyloxy)carbonyl)-O-(tert-butyl)-L-seryl-L-aspartate; Z-Ser(OtBu)-Asp(OtBu)-OMe. Grade: ≥95%. Molecular formula: C24H36N2O8. Mole weight: 480.56. | |
| Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-OH | Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-OH is a protected tripeptide used in peptide synthesis. The peptide consists of serine (Ser), aspartic acid (Asp), and tyrosine (Tyr) residues. The Cbz (Carbobenzyloxy) group protects the N-terminus of the serine residue, while the OtBu (tert-butyl) groups protect the hydroxyl and carboxyl side chains of the serine, aspartic acid, and tyrosine residues, preventing them from participating in unwanted side reactions during synthesis. The C-terminus of the tyrosine residue is free, indicated by -OH, allowing for further coupling or deprotection. This protected tetrapeptide is designed to be incorporated into larger peptide sequences in a controlled manner, ensuring selective reactivity and stability throughout the synthesis process. Synonyms: SDY; (5S,8S,11S)-8-(2-(tert-Butoxy)-2-oxoethyl)-11-(4-(tert-butoxy)benzyl)-5-(tert-butoxymethyl)-3,6,9-trioxo-1-phenyl-2-oxa-4,7,10-triazadodecan-12-oic acid; Z-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-OH; Cbz-Ser(tBu)-Asp(tBu)-Tyr(tBu)-OH. Grade: ≥95%. Molecular formula: C36H51N3O10. Mole weight: 685.82. | |
| Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH | Cbz-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH is a protected tetrapeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the first serine (Ser) residue, preventing it from participating in undesired reactions during synthesis. The side chains of the serine (Ser), aspartic acid (Asp), and tyrosine (Tyr) residues are protected by OtBu (tert-butyl) groups, which shield the hydroxyl and carboxyl groups, ensuring that these functional groups remain inactive until selective deprotection. The final Ser residue has a free carboxyl group at the C-terminus, indicated by -OH, which allows for further modifications or coupling reactions. This peptide is designed to incorporate serine, aspartic acid, and tyrosine into peptide structures, with the protective groups ensuring controlled and efficient synthesis. Synonyms: SDYS; N-((S)-2-((S)-2-((S)-2-(((Benzyloxy)carbonyl)amino)-3-(tert-butoxy)propanamido)-4-(tert-butoxy)-4-oxobutanamido)-3-(4-(tert-butoxy)phenyl)propanoyl)-O-(tert-butyl)-L-serine; Z-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-OH; Cbz-Ser(tBu)-Asp(tBu)-Tyr(tBu)-Ser(tBu)-OH. Grade: ≥97%. Molecular formula: C43H64N4O12. Mole weight: 829.00. | |
| Cbz-Ser(tBu)-Ser(tBu)-Gly-OH | Cbz-Ser(tBu)-Ser(tBu)-Gly-OH is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the serine (Ser) residue, preventing it from participating in unwanted reactions during synthesis. The hydroxyl groups on both serine residues are protected by tBu (tert-butyl) groups, which keep these groups from reacting until they are selectively deprotected. Gly (Glycine) is the final amino acid in the sequence, and the -OH at the C-terminus indicates a free carboxyl group. This free carboxyl group allows for further peptide coupling or modification. This compound is used to incorporate serine and glycine into peptides while maintaining control over the reactivity of functional groups through specific protection strategies. Synonyms: SSG; Cbz-Ser(OtBu)-Ser(OtBu)-Gly-OH; Z-Ser(tBu)-Ser(tBu)-Gly-OH; N-(N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-seryl)-O-(tert-butyl)-L-serylglycine. Grade: ≥95%. Molecular formula: C24H37N3O8. Mole weight: 495.57. | |
| Cbz-Ser(tBu)-Ser(tBu)-Gly-OMe | Cbz-Ser(tBu)-Ser(tBu)-Gly-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the serine (Ser) residue, preventing it from reacting during synthesis. The hydroxyl groups on both serine residues are protected by tBu (tert-butyl) groups, which shield these groups from reactivity until they are selectively deprotected. Gly (Glycine), the final amino acid in the sequence, is the smallest and most flexible amino acid, with the OMe (methyl ester) at the C-terminus indicating that the carboxyl group of glycine is esterified. This esterification is useful for controlling reactivity or facilitating further modifications. This compound is used to introduce serine and glycine into peptides while maintaining precise control over functional group reactivity through selective protection. Synonyms: SSG; Methyl N-(N-((benzyloxy)carbonyl)-O-(tert-butyl)-L-seryl)-O-(tert-butyl)-L-serylglycinate; Z-Ser(tBu)-Ser(tBu)-Gly-OMe; Cbz-Ser(OtBu)-Ser(OtBu)-Gly-OMe. Grade: ≥95%. Molecular formula: C25H39N3O8. Mole weight: 509.60. | |
| Cbz-Ser(tBu)-Ser(tBu)-OH | Cbz-Ser(tBu)-Ser(tBu)-OH is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group serves as a protective group for the N-terminus of the first serine residue, preventing unwanted reactions during the synthesis process. Each Ser (Serine) residue is protected at its hydroxyl side chain by a tBu (tert-butyl) group, ensuring that these reactive groups remain unaltered until selective deprotection is required. The -OH at the C-terminus indicates a free carboxyl group, allowing for further coupling reactions in the peptide chain. This compound is used to incorporate serine residues into peptides, with specific protections to facilitate precise and controlled synthesis. Synonyms: N-(N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-seryl)-O-(tert-butyl)-L-serine; N-Benzoxycarbonyl-O-tert-butyl-L-seryl-O-tert-butyl-L-serine; SS; Cbz-Ser(OtBu)-Ser(OtBu)-OH; Z-Ser(tBu)-Ser(tBu)-OH. Grade: ≥95%. CAS No. 119439-59-7. Molecular formula: C22H34N2O7. Mole weight: 438.51. | |
| Cbz-s-phenyl-L-cysteine methyl ester | Cbz-s-phenyl-L-cysteine methyl ester. Alternative Names: CBZ-S-PHENYL-L-CYSTEINE METHYL ESTER;N-CARBOBENZOXY-2-PHENYL-L-CYSTEINEMETHYLESTER;METHYL N-[(BENZYLOXY)CARBONYL]-S-PHENYL-L-CYSTEINATE. CAS No. 153277-33-9. Product ID: ACM153277339. Molecular formula: C18H19NO4S. Mole weight: 345.41. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Cbz-Thr(OtBu)-Phe-Thr(OtBu)-OMe | Cbz-Thr(OtBu)-Phe-Thr(OtBu)-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the threonine (Thr) residue, preventing it from participating in unwanted reactions. The hydroxyl groups on both threonine residues are protected by OtBu (tert-butyl) groups, ensuring these functional groups remain unreactive until selective deprotection is required. Phe (Phenylalanine), positioned in the middle, adds aromatic and hydrophobic properties to the peptide. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the final threonine is esterified, which can facilitate further reactions or modifications. This compound is used to incorporate threonine and phenylalanine into peptides, with controlled reactivity through selective protection, enabling precise and efficient peptide synthesis. Synonyms: TFT; Cbz-Thr(tBu)-Phe-Thr(tBu)-OMe; Z-Thr(OtBu)-Phe-Thr(OtBu)-OMe; Methyl N-N-((benzyloxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanyl-O-(tert-butyl)-L-threoninate. Grade: ≥95%. Molecular formula: C34H49N3O8. Mole weight: 627.78. | |
| Cbz-Thr-Phe-Thr(tBu)-OMe | Cbz-Thr-Phe-Thr(tBu)-OMe is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the first threonine (Thr) residue, preventing it from participating in unwanted reactions during the synthesis process. The side chain of the second threonine residue is protected by a tBu (tert-butyl) group, shielding the hydroxyl group from reactivity until selective deprotection is needed. Phe (Phenylalanine), the middle amino acid, contributes aromatic and hydrophobic properties to the peptide sequence. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the second threonine is esterified, which is useful for controlling the reactivity and allowing further modifications or elongation of the peptide chain. This compound is employed to introduce threonine and phenylalanine into peptides, with specific protections to ensure selective and controlled synthesis. Synonyms: TFT; Methyl N-((benzyloxy)carbonyl)-L-threonyl-L-phenylalanyl-O-(tert-butyl)-L-threoninate; Z-Thr-Phe-Thr(tBu)-OMe. Grade: ≥95%. Molecular formula: C30H41N3O8. Mole weight: 571.67. | |
| Cbz-Thr(tBu)-Phe-OH | Cbz-Thr(tBu)-Phe-OH is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the threonine residue, preventing reactions at this site during synthesis. The Thr (Threonine) residue is further protected at its hydroxyl side chain by a tBu (tert-butyl) group, ensuring the hydroxyl group remains unreactive until deprotection is desired. Phe (Phenylalanine) is the second amino acid, contributing aromatic character to the peptide. The -OH at the C-terminus signifies a free carboxyl group, which can participate in peptide bond formation. This compound is used to introduce threonine and phenylalanine into peptides with specific protective measures for controlled and selective synthesis. Synonyms: N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanine; Z-Thr(tBu)-Phe-OH; N-Benzoxycarbonyl-O3-tert-butyl-L-threonyl-L-phenylalanine; TF; L-Phenylalanine, N-[O-(1,1-dimethylethyl)-N-[(phenylmethoxy)carbonyl]-L-threonyl]-. Grade: ≥95%. CAS No. 47732-07-0. Molecular formula: C25H32N2O6. Mole weight: 456.54. | |
| Cbz-Thr(tBu)-Phe-Thr(tBu)-OH | Cbz-Thr(tBu)-Phe-Thr(tBu)-OH is a protected tripeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the threonine (Thr) residue, preventing it from reacting during synthesis. Both threonine residues have their side chain hydroxyl groups protected by tBu (tert-butyl) groups, which shield these groups from unwanted reactions until deprotection is desired. Phe (Phenylalanine), the central amino acid in the sequence, adds aromatic and hydrophobic properties to the peptide. The -OH at the C-terminus indicates a free carboxyl group, allowing for further peptide coupling. This compound is used to incorporate threonine and phenylalanine into peptides while maintaining control over the functional groups' reactivity through selective protection. Synonyms: TFT; N-N-((Benzyloxy)carbonyl)-O-(tert-butyl)-L-threonyl-L-phenylalanyl-O-(tert-butyl)-L-threonine; Z-Thr(tBu)-Phe-Thr(tBu)-OH; Cbz-Thr(OtBu)-Phe-Thr(OtBu)-OH. Grade: ≥95%. Molecular formula: C33H47N3O8. Mole weight: 613.75. | |
| Cbz-Tyr(OtBu)-Ser(OtBu)-OMe | Cbz-Tyr(OtBu)-Ser(OtBu)-OMe is a protected dipeptide used in peptide synthesis. The Cbz (Carbobenzyloxy) group protects the N-terminus of the tyrosine (Tyr) residue, preventing it from reacting during synthesis. The hydroxyl group of tyrosine is protected by an OtBu (tert-butyl) group, ensuring it remains unreactive until deprotection is necessary. The Ser (Serine) residue is similarly protected at its hydroxyl group by an OtBu group. The OMe (methyl ester) at the C-terminus indicates that the carboxyl group of the serine is esterified, facilitating further peptide coupling or modification. This compound is used to introduce tyrosine and serine into peptides while controlling the reactivity of their functional groups. Synonyms: Z-Tyr(OtBu)-Ser(OtBu)-OMe; Methyl N-((S)-2-(((benzyloxy)carbonyl)amino)-3-(4-(tert-butoxy)phenyl)propanoyl)-O-(tert-butyl)-L-serinate; YS. Grade: ≥95%. Molecular formula: C29H40N2O7. Mole weight: 528.65. | |
| CC0651 | CC0651 is an allosteric inhibitor of the human Cdc34 ubiquitin-conjugating enzyme. CC0651 potently (IC50=1.72 μM) inhibits the ubiquitination of p27Kip1, as confirmed by dose-response analysis. Uses: Scientific research. Category: Signaling pathways. CAS No. 1319207-44-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15301. | |
| CC0651 | CC0651, a Cdc34 ubiquitin-conjugating enzyme allosteric inhibitor, has been found to restrain the cell proliferation at some extent in cancer cell lines PC-3. IC50: 1.72 uM (inhibited the ubiquitination of p27 Kip1). Uses: Cc0651 is a cdc34 ubiquitin-conjugating enzyme allosteric inhibitor that has been found to restrain the cell proliferation at some extent in cancer cell lines pc-3. ic50: 1.72 um (inhibited the ubiquitination of p27 kip1). Synonyms: CC0651; CC 0651; CC-0651; (2R,3S,4S)-5-[4-(3,5-dichlorophenyl)phenyl]-2,3-dihydroxy-4-[(2-methoxyacetyl)amino]pentanoicacid; CC0651; 1319207-44-7; 4,5-Dideoxy-5-(3',5'-Dichlorobiphenyl-4-Yl)-4-[(Methoxyacetyl)amino]-L-ArabinonicAcid; U94; SCHEMBL14884531. Grade: 95%. CAS No. 1319207-44-7. Molecular formula: C20H21Cl2NO6. Mole weight: 442.29. | |
| CC-1065 | CC-1065 is originally isolated from Streptomyces zelensis and its bioactivity was very strong. CC-1065 is against gram-positive bacteria with the MIC=1-10 ng/mL, against most gram-negative bacterial and fungi with the MIC of 1 μg/mL. Synonyms: Antibiotic CC 1065; NSC298223; CCRIS 2174. CAS No. 69866-21-3. Molecular formula: C37H33N7O8. Mole weight: 703.70. | |
| CC-1088 | CC-1088 is an analog of thalidomide with potential antineoplastic activity that belongs to the functional class of agents called selective cytokine inhibitory drugs (SelCIDs). Uses: Cytokine inhibitor. Synonyms: CC1088; CC 1088; CC-1088. 3-(1,3-dioxoisoindolin-2-yl)-3-phenylpropanamide. Grade: ≥98%. CAS No. 467421-06-3. Molecular formula: C17H14N2O3. Mole weight: 294.31. | |
| CC-115 | CC-115, a DNA-PK and mTOR inhibitor, has been found to have probable anticarcinoma effect. IC50:13 nM and 21 nM for DNA-PK and mTOR respectively. Uses: Cc-115 is a dna-pk and mtor inhibitor and has been found to have probable anticarcinoma effect. Synonyms: 1-ethyl-7-(2-methyl-6-(1H-1,2,4-triazol-5-yl)pyridin-3-yl)-3,4-dihydropyrazino[2,3-b]pyrazin-2(1H)-one; CC115 ; CC-115; CC 115. Grade: 98%. CAS No. 1228013-15-7. Molecular formula: C16H16N8O. Mole weight: 336.35. | |
| CC-115 | CC-115 is a potent and dual DNA-PK and mTOR kinase inhibitor with IC50s of 13 nM and 21 nM, respectively. CC-115 blocks both mTORC1 and mTORC2 signaling. Uses: Scientific research. Category: Signaling pathways. CAS No. 1228013-15-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16962. | |
| CC-115 hydrochloride | The hydrochloride salt form of CC-115 which is a mTOR / DNA-PK inhibitor that probably has antineoplastic effect through influencing the cellular proliferation of cancer cells. IC50: 21 nM and 13 nM for mTOR and DNA-PK respectively. Uses: The hydrochloride salt form of cc-115 which is a mtor / dna-pk inhibitor that probably has antineoplastic effect through influencing the cellular proliferation of cancer cells. Synonyms: CC115 hydrochloride ; CC-115 hydrochloride; CC 115 hydrochloride. Grade: 98%. CAS No. 1300118-55-1. Molecular formula: C16H17ClN8O. Mole weight: 372.81. | |
| CC-12074 | A Metabolite of Pomalidomide. Uses: Pomalidomide metabolite. Synonyms: CC-12074; CC12074; CC 12074; Pomalidomide metabolite M19; UNII-A480CC1Z8I; SCHEMBL3742152.4-amino-2-(5-hydroxy-2,6-dioxopiperidin-3-yl)isoindole-1,3-dione. Grade: ≥98%. CAS No. 460741-57-5. Molecular formula: C13H11N3O5. Mole weight: 289.24. | |
| CC122 | CC122 is a novel agent for DLBCL. It is an orally available pleiotropic pathway modulator. It has antitumor and immunomodulatory activity. It is used for the treatment of chronic lymphocytic leukemia. It binds CRBN and degrades Aiolos and Ikaros resulting in a mimicry of IFN signaling and apoptosis in DLBCL. It inhibits proliferation and induces apoptosis in ABC and GCB DLBCL in vitro. It was developed by Celgene Corporation(CELG) and was in clinic phase 2 trial. Uses: Cc122 has antitumor and immunomodulatory activity. it is used for the treatment of chronic lymphocytic leukemia. Synonyms: 3-(5-Amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione; CC-122; CC122; CC 122. Grade: >98 %. CAS No. 1015474-32-4. Molecular formula: C14H14N4O3. Mole weight: 286.29. | |
| CC-17368 | CC-17368 is a hydroxyisoindole derivative and metabolite of pomalidomide that has potential activity in anticancer study like multiple myeloma. Synonyms: CC 17368; CC17368; Pomalidomide metabolite M17; 1H-Isoindole-1,3(2H)-dione, 4-amino-2-(2,6-dioxo-3-piperidinyl)-5-hydroxy-. Grade: 98%. CAS No. 1547162-41-3. Molecular formula: C13H11N3O5. Mole weight: 289.25. | |
| CC-17369 | CC-17369, a hydroxyisoindole derivative, is a metabolites of pomalidomide and has potential activity in anticancer study like multiple myeloma. Synonyms: CC-17369; CC 17369; CC17369; Pomalidomide metabolite M16; M16(CC-17369); SCHEMBL15439588; 4-amino-2-(2,6-dioxopiperidin-3-yl)-7-hydroxyisoindole-1,3-dione. Grade: 98%. CAS No. 1547162-46-8. Molecular formula: C13H11N3O5. Mole weight: 289.25. | |
| CC-223 | CC-223, a mTOR kinase inhibitor, has been found to be effective in inducing the apoptosis and reducing the proliferation of tumor cells. It is still under Phase I/II clinical trial by Celgene Corporation. IC50: 16 nM. Uses: Cc-223 is a mtor kinase inhibitor that has been found to be effective in inducing the apoptosis and reducing the proliferation of tumor cells. Synonyms: CC-223; CC 223; CC223; UNII-I8RA3543SY; I8RA3543SY; 7-(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino(2,3-b)pyrazin-2(1H)-one; 7-(6-(2-Hydroxypropan-2-yl)pyridin-3-yl)-1-(trans-4-methoxycyclohexyl)-3,4-dihydropyrazino[2,3-b]pyraz. Grade: 98%. CAS No. 1228013-30-6. Molecular formula: C21H27N5O3. Mole weight: 397.47. | |
| CC260 | CC260 is a selective PI5P4Kα and PI5P4Kβ inhibitor with Kis of 40 nM and 30 nM, respectively. CC260 does not inhibit or weakly inhibits other protein kinases, such as Plk1 and RSK2. CC260 can be used for cell energy metabolism, diabetes and cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2411088-26-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-139188. | |
| CC-3052 | CC-3052, a thalidomide analogue, reduces persistent activation of the TNF-α system in HIV without markedly impairing neutrophil viability. Synonyms: CC-3052; CC 3052; CC3052; methyl (2R)-2-(3,4-dimethoxyphenyl)-3-(3-oxo-1H-isoindol-2-yl)propanoate. Grade: >98%. CAS No. 216884-02-5. Molecular formula: C20H21NO5. Mole weight: 355.38. | |
| CC-3060 | CC-3060 is a molecular glue modulator targeting Cereblon (CRBN) E3 ubiquitin ligase and ZBTB16 degrader with a DC50 of 0.47 nM in HT-1080 cells. CC-3060 engages structural degrons on ZBTB16s ZnF1 or ZnF3 domains for fusion protein substrates. CC-3060 can be used for the research of acute promyelocytic leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 444288-86-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-153698. | |
| CC-3240 | CC-3240 (compound 13) is a molecular glue degrader of CaMKK2 based on CC-8977, with the IC50 of 9 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2922675-91-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163064. | |
| CC4 | CC4 is a selective α6β2 and α4β2 nAChR partial agonist (Ki = 12 and 26nM for rat α6β2 and α4β2 receptors, respectively). CC4 stimulates dopamine release from striatal slices in vitro, and attenuates nicotine-induced self-administration and conditional place preference in vivo. Synonyms: CC4; CC 4; CC-4; Alternine; Ethylenedi-cytisine; (1R,5S)-1,2,3,4,5,6-Hexahydro-3-[2-[(1R,5S)-1,5,6,8-tetrahydro-8-oxo-1,5-methano-2H-pyrido[1,2-a][1,5]diazocin-3(4H)-yl]ethyl]-1,5-methano-8H-pyrido[1,2-a][1,5]diazocin-8-one. Grade: ≥98% by HPLC. CAS No. 492-02-4. Molecular formula: C24H30N4O2. Mole weight: 406.52. | |
| CC-401 | CC-401 is a second generation ATP-competitive anthrapyrazolone c-Jun N terminal kinase (JNK) inhibitor with potential antineoplastic activity. The activation of JNK signaling is indentified in many immune-mediated kidney disease models. Thus, as the JNK inhibitor, CC-401 is found to be effective in these renal injury models. Synonyms: CC-401; CC 401; CC401. Grade: >98%. CAS No. 395104-30-0. Molecular formula: C22H24N6O. Mole weight: 388.47. | |
| CC-401 | CC-401 is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 395104-30-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-13022A. | |
| CC 401 dihydrochloride | CC 401 dihydrochloride is a potent JNK inhibitor (Ki = 25-50 nM). CC 401 competitively binds to ATP-binding site of phosphorylated JNK to inhibit JNK. Uses: Hepatoprotective. Synonyms: CC-401 dihydrochloride; CC 401 dihydrochloride; CC401 dihydrochloride; 3-[3-[2-(1-Piperidinyl)ethoxy]phenyl]-5-(1H-1,2,4-triazol-5-yl)-1H-indazole dihydrochloride. Grade: ≥98% by HPLC. CAS No. 2250025-96-6. Molecular formula: C22H24N6O.2HCl. Mole weight: 461.39. | |
| CC-401 hydrochloride | ATP-competitive, selective JNK inhibitor. Decreases c-Jun transcription activity and proliferation. Decreases cytochrome c release and caspase 3 activation. Shows anti-ischemic, anti-inflammatory and antiapoptotic effects in vivo. Synonyms: CC 401 hydrochloride; CC401 hydrochloride; CC401 HCl. Grade: >98%. CAS No. 1438391-30-0. Molecular formula: C22H25ClN6O. Mole weight: 424.93. | |
| CC-401 hydrochloride | CC-401 hydrochloride is a potent inhibitor of all three forms of JNK with Ki of 25 to 50 nM. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC401 HCl. CAS No. 1438391-30-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13022. | |
| CC-5013 (Lenalidomide) | Lenalidomide is a TNF-α secretion inhibitor with IC50 of 13 nM in PBMCs. Lenalidomide (CC-5013) is a ligand of ubiquitin E3 ligase cereblon (CRBN), and it causes selective ubiquitination and degradation of two lymphoid transcription factors, IKZF1 and IKZF3, by the CRBN-CRL4 ubiquitin ligase. Lenalidomide promotes cleaved caspase-3 expression and inhibit VEGF expression and induces apoptosis. Group: Inhibitors. Alternative Names: CC-5013. CAS No. 191732-72-6. Pack Sizes: 1g. Product ID: S1029. Formula: C13H13N3O3. Smiles: C1CC(=O)NC(=O)C1N2CC3=C(C2=O)C=CC=C3N. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| CC-618 | CC-618 has been found to be a PPARβ/δ antagonist that could be used to study the potential biological activity of Cys249 at some extent. IC50: 10 μM. Synonyms: 5-Thiazolecarboxamide, 4-methyl-2-[4-(trifluoromethyl)phenyl]-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-; 4-Methyl-2-[4-(trifluoromethyl)phenyl]-N-[2-[[5-(trifluoromethyl)-2-pyridinyl]sulfonyl]ethyl]-5-thiazolecarboxamide; CC 618; CC618; 4-Methyl-2-(4-(trifluoromethyl)phenyl)-N-(2-((5-(trifluoromethyl)pyridin-2-yl)sulfonyl)ethyl)thiazole-5-carboxamide. Grade: 98%. CAS No. 1680204-90-3. Molecular formula: C20H15F6N3O3S2. Mole weight: 523.47. | |
| CC-647 | CC-647 is a molecular glue modulator targeting Cereblon (CRBN) E3 ubiquitin ligase. CC-647 promotes the interaction between CRBN and ZBTB16 as well as its oncogenic fusion protein RARα-ZBTB16 (with a DC50 of 103 nM). CC-647 is promising for research of ZBTB16-RARα-associated acute promyelocytic leukemia (APL)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1061605-35-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173614. | |
| CC-671 | CC-671 is a novel dual TTK Protein Kinase/CDC2-Like Kinase (CLK2) inhibitor with IC50s of 5 and 3 nM, which is used for the treatment of triple negative breast cancer initiated from a phenotypic screen. It is selective for Mps1/TTK and Clk2 over a panel of 255 kinases at 3 μM, but does inhibit DYRK3, DYRK1A, PHKG, DYRK1B, and Clk1 (IC50s = 99, 104, 136, 157, and 300 nM, respectively). Synonyms: CC671; CC 671. Grade: ≥95%. CAS No. 1618658-88-0. Molecular formula: C28H28N6O4. Mole weight: 512.6. | |
| CC-671 | CC-671 is a dual TTK protein kinase/CDC2-like kinase (CLK2) inhibitor with IC50s of 0.005 and 0.006 μM for TTK and CLK2, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1618658-88-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108709. | |
| CC-885 | CC-885 is a cereblon (CRBN) modulator with an anti-tumour activity mediated through the cereblon-dependent ubiquitination and degradation of the translation termination factor GSPT1. CC-885 potently suppresses the proliferation of human acute myeloid leukaemia (AML) tumour cell lines. Uses: Antitumor agent. Synonyms: CC 885; CC885; N-(3-chloro-4-methylphenyl)-N'-[[2-(2,6-dioxo-3-piperidinyl)-2,3-dihydro-1-oxo-1H-isoindol-5-yl]methyl]-urea. Grade: 99%. CAS No. 1010100-07-8. Molecular formula: C22H21ClN4O4. Mole weight: 440.88. | |
| CC-885 | CC-885 is a cereblon (CRBN) modulator with potent anti-tumour activity. CC-885 is also a known degrader of GSPT1, inhibiting protein translation. Uses: Scientific research. Category: Signaling pathways. CAS No. 1010100-07-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101488. | |
| CC-885-CH2-PEG1-NH-CH3 | CC-885-CH2-PEG1-NH-CH3 is a neoDegrader that can be used in the synthesis of Antibody neoDegrader Conjugate (AnDC). CC-885-CH2-PEG1-NH-CH3 is the toxic molecule of ADC, which can specifically degrade the target protein in cancer cells through the E3 ubiquitin ligase pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2722698-03-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-145449. | |
| CC-90001 | CC-90001 is a potent, selective and orally active inhibitor of c-Jun N-terminal kinase (JNK). CC-90001 shows 12.9-fold selectivity for JNK1 over JNK2 in a cell-based model. CC-90001 can be used for the research of idiopathic pulmonary fibrosis[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1403859-14-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138304. | |
| CC-90001 | CC-90001 is an orally available JNK inhibitor that is used in the research of Idiopathic pulmonary fibrosis (IPF) treatment. Synonyms: CC 90001; CC90001. Grade: 98% by HPLC. CAS No. 1403859-14-2. Molecular formula: C16H27N5O2. Mole weight: 321.42. | |
| CC-90002 | CC-90002 is a humanized anti-CD47 monoclonal antibody. CC-90002 binds to CD47 and inhibits CD47-SIRPα interaction. CC-90002 has been used in the research of acute myeloid leukemia. Synonyms: CC 90002; CC90002. CAS No. 2085844-54-6. | |
| CC-90002 | CC-90002 is a humanized anti-CD47 monoclonal antibody (mAb). CC-90002 has a high affinity for binding to CD47 with a subnanomolar Kd value. CC-90002 can be used for the research of hematologic malignancies and solid tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2085844-54-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99172. | |
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