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| Product | Description | |
|---|---|---|
| CC-90003 | Extracellular-signal regulated kinases (ERKs) are a specific subtype of MAPK that have been extensively linked to regulation of synaptic plasticity and memory formation in many systems. CC-90003 is an irreversible and selective inhibitor of ERK1/2 with IC50s in the 10-20 nM range, which shows good kinase selectivity and antitumor activity in a 258-kinase biochemical assay. Synonyms: CC90003; CC 90003. Grade: ≥98%. CAS No. 1621999-82-3. Molecular formula: C22H21F3N6O2. Mole weight: 458.44. |  |
| CC-90003 | CC-90003 is an irreversible and selective inhibitor of ERK 1/2 with antitumor activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 1621999-82-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112570. |  |
| CC-90005 | CC-90005 is a potent, selective and orally active inhibitor of protein kinase C-θ (PKC-θ), with an IC50 of 8 nM. CC-90005 shows selectivity for PKC-θ over PKC-δ (IC50=4440 nM). CC-90005 can inhibit T cell activation by inhibiting IL-2 expression[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1799574-70-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-132304. | |
| CC-90011 besylate | CC-90011 besylate is an orally active inhibitor of lysine specific demethylase-1 (LSD1). CC-90011 exhibits potent on-target induction of cellular differentiation in acute myeloid leukemia (AML) and small cell lung cancer (SCLC) cell lines, and antitumor efficacy in patient-derived xenograft (PDX) SCLC models. Uses: Antineoplastic agents. Synonyms: LSD1-IN-7 benzenesulfonate; Pulrodemstat besilate; CC-90011 benzenesulfonate. CAS No. 2097523-60-7. Molecular formula: C30H29F2N5O5S. Mole weight: 609.64. | |
| CC-99677 | CC-99677 is a novel, oral, and selective MK2 inhibitor with sustainable multi-cytokine inhibition for the treatment of ankylosing spondylitis and other inflammatory diseases. CC-99677 is extracted from patent WO2020236636, compound 1. CAS No. 1887069-10-4. Molecular formula: C22H20ClN5O3S. Mole weight: 469.94. | |
| CCA tRNA nucleotidyltransferase | The acylation of all tRNAs with an amino acid occurs at the terminal ribose of a 3' CCA sequence. The CCA sequence is added to the tRNA precursor by stepwise nucleotide addition performed by a single enzyme that is ubiquitous in all living organisms. Although the enzyme has the option of releasing the product after each addition, it prefers to stay bound to the product and proceed with the next addition. Group: Enzymes. Synonyms: CCA-adding enzyme; tRNA adenylyltransferase; tRNA cytidylyltransferase; tRNA CCA-pyrophosphorylase; tRNA-nucleotidyltransferase; transfer-RNA nucleotidyltransferase; transfer ribonucleic acid nucleotidyl transferase; C. Enzyme Commission Number: EC 2.7.7.72. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3284; CCA tRNA nucleotidyltransferase; EC 2.7.7.72; CCA-adding enzyme; tRNA adenylyltransferase; tRNA cytidylyltransferase; tRNA CCA-pyrophosphorylase; tRNA-nucleotidyltransferase; transfer-RNA nucleotidyltransferase; transfer ribonucleic acid nucleotidyl transferase; CTP(ATP):tRNA nucleotidyltransferase; transfer ribonucleate adenylyltransferase; transfer ribonucleate adenyltransferase; transfer RNA adenylyltransferase; transfer ribonucleate nucleotidyltransferase; ATP (CTP):tRNA nucleotidyltransferase; ribonucleic cytidylic cytidylic. |  |
| CCB02 | CCB02 is a selective CPAP-tubulin interaction inhibitor (IC50: 689 nM) with anti-tumor activity. Synonyms: CCB 02. Grade: 99%. CAS No. 2100864-57-9. Molecular formula: C14H9N3O. Mole weight: 235.24. | |
| C(Cbz)-acetic acid | C(Cbz)-acetic acid. Synonyms: 2-Oxo-4-[(benzyloxycarbonyl)amino]pyrimidine-1(2H)-acetic acid. CAS No. 144564-95-4. Molecular formula: C14H13N3O5. Mole weight: 303.27. | |
| Cc-CATH2 | Cc-CATH2 is isolated from Coturnix coturnix. Cc-CATH2 showed considerable reduction of cytotoxic activity compared to other avian cathelicidins, with average IC(50) values of 20.18μm. | |
| Cc-CATH3 | Cc-CATH3 is isolated from Coturnix coturnix. Cc-CATH3 is an avian antimicrobial peptide (AMP) with 29 amino acids in length containing a broad-spectrum antibacterial activity. Cc-CATH3 showed considerable reduction of cytotoxic activity compared to other avian cathelicidins, with average IC(50) values of 17.16 μm. | |
| CCCP | CCCP is an oxidative phosphorylation (OXPHOS) uncoupler. CCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Carbonyl cyanide 3-chlorophenylhydrazone; Carbonyl Cyanide m-Chlorophenylhydrazone. CAS No. 555-60-2. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-100941. | |
| CCCP | CCCP inhibits IFN-β production induced by various types of the STING pathway activators, and suppresses the phosphorylation of STING, TBK1, and IRF3 via disrupting the association of STING and TBK1. Synonyms: CCCP; Mesoxalonitrile 3-chlorophenylhydrazone; 2-[(3-chlorophenyl)hydrazinylidene]propanedinitrile; Carbonyl Cyanide m Chlorophenyl Hydrazone; Carbonyl Cyanide m-Chlorophenyl; Hydrazone; Carbonyl Cyanide meta Chlorophenyl Hydrazone; Carbonyl Cyanide meta-Chlorophenyl Hydrazone; CCCP. CAS No. 555-60-2. Molecular formula: C9H5ClN4. Mole weight: 204.62. | |
| CCCP | CCCP. Group: Biochemicals. Grades: Purified. CAS No. 555-60-2. Pack Sizes: 500mg. US Biological Life Sciences. |  Worldwide |
| CCCP (Carbonyl cyanide 3-chlorophenylhydrazone) | CCCP (Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone), an oxidative phosphorylation inhibitor, is a protonophore mitochondrial uncoupler that increases membrane permeability to protons, leading to a disruption in the mitochondrial membrane potential. Carbonyl cyanide 3-chlorophenylhydrazone (CCCP), the protonophore, can inhibits STING-mediated IFN-β production via disrupting mitochondrial membrane potential (MMP). Group: Inhibitors. Alternative Names: Carbonyl cyanide m-chlorophenyl hydrazone, Carbonyl cyanide 3-chlorophenylhydrazone. CAS No. 555-60-2. Pack Sizes: 25mg. Product ID: S6494. Formula: C9H5ClN4. Smiles: C1=CC(=CC(=C1)Cl)NN=C(C#N)C#N. Storage Conditions: 3 years -20°C powder. |  United States; Europe |
| CCCP (Standard) | CCCP (Standard) is the analytical standard of CCCP. This product is intended for research and analytical applications. CCCP is an oxidative phosphorylation (OXPHOS) uncoupler. CCCP induces activation of PINK1 leading to Parkin Ser65 phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Carbonyl cyanide 3-chlorophenylhydrazone (Standard); Carbonyl Cyanide m-Chlorophenylhydrazone (Standard). CAS No. 555-60-2. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100941R. | |
| ccc_R08 | ccc_R08 is a non-cytotoxic and orally active cccDNA inhibitor that reduces cccDNA levels in the liver of HBV-infected mice. ccc_R08 can be used in the study of HBV virus (hepatitis B virus) infection[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2919019-72-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148560. | |
| CcD1 | CcD1 is isolated from Capsicum chinense. It has antifungal activity. | |
| CCF0058981 | CCF0058981, a non-covalent SARS-CoV-2 3CLpro (SC2) inhibitor (IC50 = 68 nM), can inhibit SARS-CoV-1 3CLpro (SC1) with an IC50 of 19 nM. It has antiviral efficacy and has the potential to study COVID-19. Synonyms: CCF981; ML300-based SC inhibitor 41; N-(4-(1H-Imidazol-5-yl)phenyl)-2-(1H-benzo[d][1,2,3]triazol-1-yl)-N-(3-chlorobenzyl)acetamide. Grade: ≥98%. CAS No. 2708934-53-4. Molecular formula: C24H19ClN6O. Mole weight: 442.90. | |
| CCF642 | CCF642 is a potent protein disulfide isomerases (PDI) inhibitor with an IC50 of 2.9 μM. CCF642 causes acute endoplasmic reticulum (ER) stress in multiple myeloma cells accompanied by apoptosis-inducing calcium release. CCF642 has broad anti-multiple myeloma activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 346640-08-2. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100430. | |
| CCF-642 | CCF-642 is a protein disulfide isomerase (PDI) inhibitor that exhibits 100-fold higher potency than PACMA 31 (by di-E-GSSG assay) via an alternative mode of action. CCF642 displayed potent efficacy in an aggressive syngeneic mouse model of multiple myeloma and prolonged the lifespan of C57BL/KaLwRij mice engrafted with 5TGM1-luc myeloma, an effect comparable to the first-line multiple myeloma therapeutic bortezomib. Synonyms: 3-(4-Methoxyphenyl)-5-[(5-nitro-2-thienyl)methylene]-2-thioxo-4-thiazolidinone; CCF-642; CCF 642; CCF642. CAS No. 346640-08-2. Molecular formula: C15H10N2O4S3. Mole weight: 378.44. | |
| CCG-100602 | CCG-100602 inhibits RhoA/C-mediated, SRF-driven luciferase expression in PC-3 prostate cancer cells with an IC50 value of 9.8 μM. CCG-100602 specifically blocks the nuclear localization of MRTF-A, thereby inhibiting the fibrogenic transcription factor SRF. Synonyms: CCG-100602; 1207113-88-9; 1-[3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide; CHEMBL603141; compound 4g [PMID: 19963382]; 1-(3,5-bis(trifluoromethyl)benzoyl)-N-(4-chlorophenyl)piperidine-3-carboxamide; CCG100602; CCG 100602; GTPL6764; SCHEMBL1534209; BDBM50436237; AKOS040744973; MS-28902; HY-120855; CS-0079376; Q27075763; [3,5-bis(trifluoromethyl)benzoyl]-N-(4-chlorophenyl)piperidine-3-carboxamide; 1-[3,5-bis (trifluoromethyl)benzoyl]-N-(4-chlorophenyl)-3-piperidinecarboxamide. Grade: 98%. CAS No. 1207113-88-9. Molecular formula: C21H17ClF6N2O2. Mole weight: 478.8. | |
| CCG 1423 | CCG 1423. Group: Biochemicals. Grades: Purified. CAS No. 285986-88-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CCG-1423 | CCG-1423 is a potent inhibitor of RhoA/C-mediated gene transcription. It suppressed invasion of PC-3 prostate cancer cells in a matrigel model of metastasis. It induces intermediate mesoderm differentiation from ESCs. Synonyms: CCG 1423; N-[1-(4-chloroanilino)-1-oxopropan-2-yl]oxy-3,5-bis(trifluoromethyl)benzamide. Grade: >98%. CAS No. 285986-88-1. Molecular formula: C18H13ClF6N2O3. Mole weight: 454.75. | |
| CCG-1423 | CCG-1423 is an inhibitor of Rho/MRTF/SRF pathway. CCG-1423 shows activities in several cancer cells. CCG-1423 is a promising lead compound for the development of novel pharmacologic tools, and it can be used for the research of cancer and diabetes[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 285986-88-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-13991. | |
| CCG 203769 | CCG 203769 is a selective inhibitor of G protein signaling (RGS4). CCG 203769 blocks the RGS4-Gαo protein-protein interaction in vitro with an IC50 of 17 nM. Synonyms: RGS4 inhibitor 11b; 2-ethyl-4-butyl-1,2,4-thiadiazolidine-3,5-dione. Grade: 99%. CAS No. 410074-60-1. Molecular formula: C8H14N2O2S. Mole weight: 202.28. | |
| CCG 203769 | CCG 203769 is a selective G protein signaling (RGS4) inhibitor, which blocks the RGS4-Gαo protein-protein interaction in vitro with an IC50 of 17 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 410074-60-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-U00431. | |
| CCG 203971 | CCG 203971. Group: Biochemicals. Grades: Purified. CAS No. 1443437-74-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CCG 203971 | CCG 203971 is an inhibitor of SRE activation in the prostate cancer cell line PC-3 (IC50 = 6.4 μM). CCG 203971 inhibits fibrosis by targeting the MRTF/SRF gene transcription pathway, and inhibits proliferation of SSc-derived dermal fibroblasts. It also suppresses PC-3 cell migration in scratch wound assays (IC50 = 4.2 μM). Synonyms: CCG-203971; CCG 203971; CCG203971. N-(4-Chlorophenyl)-1-[3-(2-furanyl)benzoyl]-3-piperidinecarboxamide. Grade: ≥98% by HPLC. CAS No. 1443437-74-8. Molecular formula: C23H21ClN2O3. Mole weight: 408.88. | |
| CCG-203971 | CCG-203971 is a second-generation Rho/MRTF/SRF pathway inhibitor. CCG-203971 potently targets RhoA/C-activated SRE-luciferase (IC50 =6.4 μM). CCG-203971 inhibits PC-3 cell migration with an IC50 of 4.2 μM. Potential anti-metastasis Agent[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1443437-74-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108361. | |
| CCG 2046 | CCG 2046 is an inhibitor of regulator of G-protein signaling 4 (RGS4). It reduces the RGS4-Gαo protein-protein interaction signal. Synonyms: CCG 2046; CCG2046; CCG-2046; 3-Methyl-3-propyl-1,1,2,2-cyclopropanetetracarbonitrile; 1,1,2,2-tetracyano-3-methyl-3-propylcyclopropane. Grade: ≥99% by HPLC. CAS No. 13017-69-1. Molecular formula: C11H10N4. Mole weight: 198.22. | |
| CCG 2046 | CCG 2046. Group: Biochemicals. Grades: Purified. CAS No. 13017-69-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CCG215022 | CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor (IC50s= 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively), with good selectivity against other closely related kinases such as GRK1 and PKA. Synonyms: 4-(4-fluoro-3-((pyridin-2-ylmethyl)carbamoyl)phenyl)-N-(1H-indazol-5-yl)-6-methyl-2-oxo-1,2,3,4-tetrahydropyrimidine-5-carboxamide; CCG215022; CCG 215022; CCG-215022. CAS No. 1813527-81-9. Molecular formula: C26H22FN7O3. Mole weight: 499.5. | |
| CCG215022 | CCG215022 is a G protein-coupled receptor kinases (GRKs) inhibitor with IC50s of 0.15±0.07 μM, 0.38±0.06 μM and 3.9±1 μM for GRK2, GRK5 and GRK1, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1813527-81-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-18991. | |
| CCG-222740 | CCG-222740 is a potent and selective Rho/MRTF pathway inhibitor. CCG-222740 decreases the activation of stellate cells in vitro and in vivo, by reducing the levels of alpha smooth muscle actin (α-SMA) expression. Synonyms: CCG-222740; N-(4-chlorophenyl)-5,5-difluoro-1-(3-(furan-2-yl)benzoyl)piperidine-3-carboxamide; N-(4-chlorophenyl)-5,5-difluoro-1-[3-(furan-2-yl)benzoyl]piperidine-3-carboxamide; C23H19ClF2N2O3; CHEMBL4105348; SCHEMBL17728947; BCP31985; XBD09869; s6673; AKOS037648832; AC-35745; BS-15759; HY-121750; CS-0083153; CCG 222740; CCG222740; D81359. CAS No. 1922098-69-8. Molecular formula: C23H19ClF2N2O3. Mole weight: 444.86. | |
| CCG-222740 | CCG-222740 is an orally active and selective Rho/myocardin-related transcription factor (MRTF) pathway inhibitor[1]. CCG-222740 is also a potent inhibitor of alpha-smooth muscle actin protein expression. CCG-222740 effectively reduces fibrosis in skin and blocks melanoma metastasis[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1922098-69-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-121750. | |
| CCG-224406 | CCG-224406 is a highly selective and potent inhibitor of G Protein-Coupled Receptor Kinase 2 (IC50= 130 nM), with 700-fold selectivity over other GRK subfamilies, and no detectable inhibition of ROCK1. Synonyms: CCG 224406; CCG224406; N-(1H-Indazole-5-yl)-2-oxo-4-[3-(2,6-dimethoxybenzylcarbamoyl)-4-fluorophenyl]-6-methyl-1,2,3,4-tetrahydropyrimidine-5-carboxamide. Grade: >98%. CAS No. 1870843-22-3. Molecular formula: C29H27FN6O5. Mole weight: 558.57. | |
| CCG 232601 | CCG 232601 is a selective and orally bioactive inhibitor of the Rho/MRTF/SRF signaling pathway (IC50 value of 0.55 μM (SRE.L assay)) as a potential antifibrotic therapeutic for systemic scleroderma. CCG-232601 inhibits the development of bleomycin-induced dermal fibrosis in mice when administered orally. Synonyms: N-(4-chlorophenyl)-5,5-difluoro-1-(3-pyridin-4-ylbenzoyl)piperidine-3-carboxamide; CCG-232601; CCG 232601; CCG232601. Grade: 99%. CAS No. 1922099-21-5. Molecular formula: C24H20ClF2N3O2. Mole weight: 455.88. | |
| CCG-232601 | CCG-232601 (compound 8f) is a potent and orally active Rho/MRTF/SRF transcriptional pathway inhibitor. CCG-232601 inhibits the development of Bleomycin-induced dermal fibrosis in mice. CCG-232601 has the potential for the research of antifibrotic for systemic scleroderma[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1922099-21-5. Pack Sizes: 1 mg. Product ID: HY-111432. | |
| CCG273441 | CCG273441 is a covalent inhibitor of G protein-coupled receptor (GPCR) kinase 5 (GRK5) with an IC50 value of 3.8 nM. CCG273441 is highly selective to GRK5 over GRK2 (IC50=4.8 μM) by binding Cys474, a GRK5 subfamily-specific residue, as a covalent handle[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2750414-35-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-47573. | |
| CCG 50014 | CCG 50014. Group: Biochemicals. Grades: Purified. CAS No. 883050-24-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CCG 50014 | CCG 50014 is a potent and selective inhibitor of RGS4 with IC50 of 30 nM, exhibiting >20-fold selectivity over other RGS proteins. Synonyms: CCG50014; CCG-50014; 4-(4-fluorobenzyl)-2-p-tolyl-1,2,4-thiadiazolidine-3,5-dione. Grade: >98%. CAS No. 883050-24-6. Molecular formula: C16H13FN2O2S. Mole weight: 316.35. | |
| CCG-50014 | CCG-50014 is the most potent against the regulator of G-protein signaling protein type 4 (RGS4) (IC50 =30 nM) and is >20-fold selective for RGS4 over other RGS proteins. CCG-50014 binds covalently to the RGS, forming an adduct on two cysteine residues located in an allosteric regulatory site[1]. CCG50014, reduces nociceptive responses and enhances opioid-mediated analgesic effects in the mouse formalin test[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 883050-24-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13509. | |
| CCG 63802 | CCG 63802. Group: Biochemicals. Grades: Purified. CAS No. 620112-78-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CCG-63802 | CCG-63802 is a reversible inhibitor of regulator of G-protein signaling (RGS) protein. It is selective amongst RGS proteins, with greatest potency at RGS4. It also inhibits GTPase accelerating protein activity of RGS4, blocks its interaction with Gαo, and retains activity under reducing conditions. Synonyms: CCG-4986; CCG 4986; CCG4986. Grade: >98%. CAS No. 620112-78-9. Molecular formula: C26H18N4O2S. Mole weight: 450.51. | |
| CCG-63808 | CCG-63808 is a reversible inhibitor of regulator of G-protein signaling (RGS) proteins. Synonyms: CCG-63808; CCG 63808; CCG63808. Grade: >98%. CAS No. 620113-73-7. Molecular formula: C25H15FN4O2S. Mole weight: 454.48. | |
| Cc-GRP | Cc-GRP is a peptide with a molecular weight of 7kDa and it was observed to display homology to GRPs. Cc-GRP has antifungal activity. | |
| CCHa2 | CCHa2. Synonyms: H-Gly-Cys-Gln-Ala-Tyr-Gly-His-Val-Cys-Tyr-Gly-Gly-His-NH2. Molecular formula: C57H79N19O16S2. Mole weight: 1350.48. | |
| Cci I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 55°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme about 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. T↑CATGA AGTAC↓T. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer W, BSA. Storage: -20°C. Form: Liquid. Source: Curtobacterium citreus. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1094RE. | |
| CciN I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Adenovirus-2 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 95% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GC↑GGCCGC CGCCGG↓CG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: Curtobacterium citreus N. Pack: 10 mM Tris-HCl (pH 7.5); 100 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Store at -20°C. Cat No: ET-1095RE. | |
| CCK (26-30) (sulfated) | Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (26-30) is an N-terminal fragment of CCK, the sulfated form of CCK (26-30) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 10% at 0.1 mM. Synonyms: N-Acetyl cholecystokinin (26-30) (sulfated). Grade: ≥95%. CAS No. 89911-69-3. Molecular formula: C33H41N7O12S2. Mole weight: 791.85. | |
| CCK (26-31) (sulfated) | Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (26-31) is an N-terminal fragment of CCK, the sulfated form of CCK (26-31) inhibits binding of [125I]CCK-33 to guinea pig cortical membranes by 21% at 0.1 mM. Synonyms: N-Acetyl cholecystokinin (26-31) (sulfated). Grade: ≥95%. CAS No. 89911-65-9. Molecular formula: C38H50N8O13S3. Mole weight: 923.05. | |
| CCK (27-33) (non-sulfated) | Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK (27-33) is a C-terminal fragment of CCK. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes with IC50 of 4 μM and inhibits electrically-stimulated contraction of isolated guinea pig ileum with IC50 of 17 μM. Synonyms: Cholecystokinin (27-33) (non-sulfated). Grade: ≥95%. CAS No. 47910-79-2. Molecular formula: C45H57N9O10S2. Mole weight: 948.12. | |
| CCK-4 Acetate | Tetragastrin is a tetrapeptide. Synonyms: CCK-4; CCK4; CCK 4; Gastrin Tetrapeptide; Cholecystokinin Octapeptide (5-8); Cholecystokinin Tetrapeptide; Gastrin (14-17) (human). CAS No. 35144-91-3. Molecular formula: C29H36N6O6S. Mole weight: 596.70. | |
| CCK-A receptor inhibitor 1 | CCK-A receptor inhibitor 1 is an inhibitor of cholecystokinin A (CCK-A) receptor with a binging IC50 of 340 nM. Synonyms: Pentanoic acid, 5-[(3-methoxypropyl)pentylamino]-4-[(2-naphthalenylsulfonyl)methyl]-5-oxo-; 5-[(3-Methoxypropyl)(pentyl)amino]-4-[(2-naphthylsulfonyl)methyl]-5-oxopentanoic acid. Grade: ≥95%. CAS No. 137004-80-9. Molecular formula: C25H35NO6S. Mole weight: 477.61. | |
| CCKBR agonist-1 | CCKBR agonist-1 (Compound 3r1) is a Gq-protein-preferring cholecystokinin B receptor (CCKBR) agonist with an EC50 of 35 pM. CCKBR agonist-1 significantly increases the survival rate of neurons, with an EC50 of 37 pM. CCKBR agonist-1 can improve the cognitive decline in mice by upregulating α-secretase (ADAM10) and calcium signaling molecule PLCB4, reduce the number of amyloid β (Aβ) plaques, and promote long-term potentiation (LTP). CCKBR agonist-1 can be used for the study of Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2923120-30-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P11540. | |
| CCK-B Receptor Antagonist 1 | CCK-B Receptor Antagonist 1 is a cholecystokinin B (CCK-B) receptor antagonist with the potential to reduce gastric acid secretion. Synonyms: Urea, N-[1-(3,3-dimethyl-2-oxobutyl)-2,3-dihydro-2-oxo-5-(2-pyridinyl)-1H-1,4-benzodiazepin-3-yl]-N'-[3-(methylamino)phenyl]-; 1-[1-(3,3-Dimethyl-2-oxobutyl)-2-oxo-5-(2-pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]-3-[3-(methylamino)phenyl]urea. Grade: ≥99%. CAS No. 168161-71-5. Molecular formula: C28H30N6O3. Mole weight: 498.58. | |
| CCK-B Receptor Antagonist 2 | CCK-B Receptor Antagonist 2, a potent and orally active Gastrin/CCK-B antagonist (IC50 = 0.43 nM), also inhibits gastrin/CCK-A activity with an IC50 of 1.82 μM. Synonyms: (R)-1-(3-Aminophenyl)-3-(1-(3,3-dimethyl-2-oxobutyl)-2-oxo-5-(pyridin-2-yl)-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl)urea; 1-(3-Amino-phenyl)-3-[(R)-1-(3,3-dimethyl-2-oxo-butyl)-2-oxo-5-pyridin-2-yl-2,3-dihydro-1H-benzo[e][1,4]diazepin-3-yl]-urea; 1-(3-Aminophenyl)-3-[(3R)-1-(3,3-dimethyl-2-oxobutyl)-2-oxo-5-(2-pyridinyl)-2,3-dihydro-1H-1,4-benzodiazepin-3-yl]urea. Grade: ≥98%. CAS No. 155412-88-7. Molecular formula: C27H28N6O3. Mole weight: 484.55. | |
| CCK Octapeptide (non-sulfated) | Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK Octapeptide (non-sulfated) is the non-sulfated form of the C-terminal octapeptide of CCK. Synonyms: CCK-8 (desulfated); Cholecystokinin (CCK) (26-33); 2-desulfo-cholecystokinin-8 (swine). Grade: 98%. CAS No. 25679-24-7. Molecular formula: C49H62N10O13S2. Mole weight: 1063. | |
| CCK Octapeptide, non-sulfated acetate | Cholecystokinin (CCK) is a neuropeptide and gut hormone that regulates pancreatic enzyme secretion and gastrointestinal motility, and acts as a satiety signal. CCK Octapeptide (non-sulfated) is the non-sulfated form of the C-terminal octapeptide of CCK. Synonyms: CCK-8 (desulfated) acetate; Cholecystokinin (CCK) (26-33) acetate. Molecular formula: C51H66N10O15S2. Mole weight: 1123.26. | |
| CCL27 | CCL27 is a chemotactic factor that attracts skin-associated memory T-lymphocytes. It may play a role in mediating homing of lymphocytes to cutaneous sites. Synonyms: C-C Motif Chemokine Ligand 27. | |
| Cc-LTP1 | Cc-LTP1 is produced by Coffea canephora. It has active antifungal activity against Candida albicans. | |
| CCM Alloy Powder | CCM is a non-magnetic, cobalt-chromium molybdenum alloy exhibiting high strength, corrosion resistance, wear resistance, and excellent biocompatibility. CCM alloy powder is produced by vacuum induction melting (VIM) followed by nitrogen gas atomization. It has excellent weldability in laser additive manufacturing processes and can be processed with either nitrogen or argon shielding gas. |  |
| CCMI | CCMI. Group: Biochemicals. Grades: Purified. CAS No. 917837-54-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CCMI | CCMI is a positive allosteric modulator of α7 neuronal nicotinic acetylcholine receptors (nAChR). It was shown to induce positive modulation of acetylcholine (ACh)-induced EC5 currents (EC50 = 0.7 μM). CCMI enhances cognition in rodent models. Synonyms: AVL-3288; AVL 3288; AVL3288; XY-4083; XY 4083; XY4083; [N-(4-Chlorophenyl)]-α-[(4-chlorophenyl)-aminomethylene]-3-methyl-5-isoxazoleacetamide; (Z)-3-(4-chloroanilino)-N-(4-chlorophenyl)-2-(3-methyl-1,2-oxazol-5-yl)prop-2-enamide. CAS No. 917837-54-8. Molecular formula: C19H15Cl2N3O2. Mole weight: 388.25. | |
| cCMP | cCMP, an intriguing cyclic cytidine monophosphate compound extensively utilized in the realm of biomedical research, has emerged as an invaluable protagonist. Affiliated with the intricacies of various signaling pathways, it conveniently serves as a second messenger, facilitating a comprehensive comprehension of cCMP's involvement in pivotal cellular functions. In the realm of immunology, its versatile nature enables it to diligently modulate the immune response, thus exhibiting promising potential in the battle against inflammatory diseases and cancerous afflictions. Synonyms: Cytidine- 3', 5'- cyclic monophosphate, sodium salt. Grade: ≥ 98% by HPLC. CAS No. 54925-33-6. Molecular formula: C9H11N3O7P · Na. Mole weight: 327.2. | |
| cCMP-AM | cCMP-AM is a membrane-permeant and metabolically activatable prodrug of cCMP, the potential further second messenger. cCMP is released after permeation and metabolism of cCMP-AM by esterases, which is trapped inside the cell and metabolized to result in a pulse-type signal. Synonyms: Cytidine- 3', 5'- cyclic monophosphate, acetoxymethyl ester. Grade: ≥ 95% by HPLC. Molecular formula: C12H16N3O9P. Mole weight: 377.2. | |
| CCMQ | CCMQ is an inhibitor of homoquinolinic acid binding to non-NMDA sensitive sites. It is combined with [3H]-homoquinolinic acid to characterize NR2B-containing NMDA receptors. Synonyms: 2-Carboxy-3-carboxymethylquinoline. CAS No. 132623-44-0. Molecular formula: C12H9NO4. Mole weight: 231.21. | |
| CCMV Gag-(7-25) | It is a cell penetrating peptide. Synonyms: H-Lys-Leu-Thr-Arg-Ala-Gln-Arg-Arg-Ala-Ala-Ala-Arg-Lys-Asn-Lys-Arg-Asn-Thr-Arg-OH; L-lysyl-L-leucyl-L-threonyl-L-arginyl-L-alanyl-L-glutaminyl-L-arginyl-L-arginyl-L-alanyl-L-alanyl-L-alanyl-L-arginyl-L-lysyl-L-asparagyl-L-lysyl-L-arginyl-L-asparagyl-L-threonyl-L-arginine. Grade: ≥95%. Molecular formula: C93H175N43O25. Mole weight: 2295.70. | |
| CCPA | CCPA (2-Chloro-N6-cyclopentyladenosine) a highly selective A1 adenosine receptors agonist with a Ki of 0.4 nM. CCPA inhibits adenylate cyclase with an IC50 of 33 nM. CCPA exhibits anti-seizure and cardiacprotective activity. CCPA can be used for the research of seizure and myocardial infarction[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 2-Chloro-N6-cyclopentyladenosine. CAS No. 37739-05-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103185. | |
| CCP peptide TFA | CCP peptide TFA is a synthetic cyclic citrullinated peptide that can be used as the substrate for detecting anti-CCP antibodies serologically. Synonyms: His-Gln-Cys-His-Gln-Glu-Ser-Thr-{Cit}-Gly-Arg-Ser-Arg-Gly-Arg-Cys-Gly-Arg-Ser-Gly-Ser (Disulfide bridge: Cys3-Cys16). Grade: 95%. Molecular formula: C89H146N41F3O34S2. Mole weight: 2455.49. | |
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