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| Product | Description | |
|---|---|---|
| CCT-251921 | CCT-251921 has been found to be a CDK inhibitor that could be significant in the studies of colorectal cancer. Synonyms: CCT251921; CCT-251921; CCT 251921; 8-(2-amino-3-chloro-5-(1-methyl-1H-indazol-5-yl)pyridin-4-yl)-2,8-diazaspiro[4.5]decan-1-one. Grade: 98%. CAS No. 1607837-31-9. Molecular formula: C21H23ClN6O. Mole weight: 410.91. |  |
| CCT365623 hydrochloride | CCT365623 hydrochloride is an orally active lysyl oxidase (LOX) inhibitor, with an IC50 of 0.89 μM. CCT365623 hydrochloride suppresses EGFR (pY1068) and AKT phosphorylation driven by EGF. CCT365623 hydrochloride is extremely well tolerated, and has good pharmacokinetic properties[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2126136-98-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124674A. |  |
| CCT373566 | CCT373566 is a potent and orally active molecular glue degrader of transcriptional repressor BCL6, with an IC50 of 2.2 nM. CCT373566 shows strong antiproliferative efficacy in vitro and reduction in tumor growth in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2378853-66-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-146185. | |
| CCTA-1523 | CCTA-1523 is a potent, selective, reversible and orally active ABCG2 inhibitor with anticancer activity. It selectively reverses ABCG2-mediated MDR in cancer cells. Synonyms: Acetamide, 2,2-dichloro-N-(3',4'-dimethoxy[1,1'-biphenyl]-3-yl)-; 2,2-Dichloro-N-(3',4'-dimethoxy[1,1'-biphenyl]-3-yl)acetamide. Grade: ≥95%. CAS No. 1616271-41-0. Molecular formula: C16H15Cl2NO3. Mole weight: 340.20. | |
| C Cushion Polyethylene Packaging Profile | Ideal for use on any type of glass, frames, appliances, furniture, glass windows, and more, our C cushion polyethylene packaging profiles are the perfect solution for all your shipping and transport needs. This reliable solution offers protection against bumps, nicks, scratches, and total breakage by absorbing impacts and vibrations to absorb the brunt of the forces associated with moving an item from one place to the next. |  |
| CCW16 | CCW16 is a cofactor for the synthesis of protein degraders, such as PROTACs CCW 28-3 (HY-156774). Uses: Scientific research. Category: Signaling pathways. CAS No. 2361138-33-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143346. | |
| CCW 28-3 | CCW 28-3 is a PROTAC-based BRD4 degrader in a proteasome- and RNF4-dependent manner (Pink: JQ-1 (carboxylic acid) (HY-78695); Black: linker (HY-170384); Blue: RNF4 ligand CCW16 (HY-143346))[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2361142-23-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156774. | |
| CCX140-B | CCX140-B is a potent CCR2 antagonist. Synonyms: CCX140; Ilacirnon. CAS No. 1100318-47-5. Molecular formula: C20H13ClF3N5O3S. Mole weight: 495.9. | |
| C-Cys-Mel | C-Cys-Mel. Synonyms: Gly-Ile-Gly-Ala-Val-Leu-Lys-Val-Leu-Thr-Thr-Gly-Leu-Pro-Ala-Leu-Ile-Ser-Trp-Ile-Lys-Arg-Lys-Arg-Gln-Gln-Cys. | |
| CD00509 | CD00509 is a tyrosyl-DNA phosphodiesterase (PDE) Tdp1 inhibitor with an IC50 of 0.71 μM. CD00509 increases DNA damage and promotes apoptosis of MCF-7 cells. CD00509 can sensitize breast cancer cells and wild-type murine embryonic fibroblasts (MEFs) to Camptothecin (CPT) (HY-16560). CD00509 can be used for the study of cancers such as breast cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 27430-18-8. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W177546. | |
| CD12681 | CD12681 is a potent and selective RORγ inverse agonist with IC50 of 19 nM. CD12681 was indentified as a preclinical candidate for the topical treatment of psoriasis. Synonyms: N-(2,4-Dimethylphenyl)-N-isobutyl-2-oxo-1-((tetrahydro-2H-pyran-4-yl)methyl)-2,3-dihydro-1H-benzo[d]imidazole-5-sulfonamide. Grade: 99%. CAS No. 1952239-59-6. Molecular formula: C25H33N3O4S. Mole weight: 471.61. | |
| CD1530 | CD1530 is a potent and selective retinoic acid receptor(RAR) agonist with Ki values of 150, 1500 and 2750 nM for RARγ, RARβ and RARα receptors respectively. It was also a potent CYP26A1 inhibitor as ketoconazole with an IC50 value of 530 nM. It inhibited excessive ROS production in tongue epithelial cells in vitro. It demonstrates transcriptional activity at RARγ with an AC50 value of 1.8 nM. It has been shown to preserve human tendon stem cell characteristics, promote repair of injured skeletal muscle, and in combination with bexarotene to inhibit oral carcinogenesis. Synonyms: 4-(6-Hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid; CD 1530; CD-1530; Benzoic acid, 4-(6-hydroxy-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)-; 4-[7-(Adamantan-1-yl)-6-hydroxy-2-naphthyl]benzoic acid. Grade: ≥95%. CAS No. 107430-66-0. Molecular formula: C27H26O3. Mole weight: 398.49. | |
| CD1530 | CD1530 is an orally active, selective RARγ agonist and antibacterial agent. CD1530 reduces Smad1/5/8 phosphorylation and overall Smad levels. CD1530 reduces β-catenin, MMP9 protein, and ROS levels. CD1530 exhibits activities such as inhibiting heterotopic ossification, promoting Achilles tendon healing, and inhibiting muscle fatty infiltration. CD1530 can be used in the research of orthopedic diseases (such as heterotopic ossification, Achilles tendon injury), muscle diseases (such as muscle fatty infiltration-related diseases)[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. CAS No. 107430-66-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108527. | |
| CD 1530 | CD 1530. Group: Biochemicals. Grades: Purified. CAS No. 107430-66-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| CD161 | CD161 is a potent, selective and orally active BET bromodomain inhibitor with Ki values of 8.2 nM and 1.4 nM for BRD4 BD1 and BD2, respectively. In human leukemia cell lines MV4-11 and MOLM-13, CD161 strongly inhibits cell growth and induces apoptosis, with IC50s <100 nM. Synonyms: CD-161; CD 161; 4-(6-Methoxy-2-methyl-4-(quinolin-4-yl)-9H-pyrimido[4,5-b]indol-7-yl)-3,5-dimethylisoxazole. Grade: 98%. CAS No. 1627716-22-6. Molecular formula: C26H21N5O2. Mole weight: 435.48. | |
| CD163 Antibody [P12L8] | CD163 Antibody [P12L8]. Group: Antibodies. Pack Sizes: 20uL. Product ID: F1548. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| CD-2 | CD-2 (Part#: 1088) |  |
| CD20 (188-196) | CD20 (188-196) is a truncated fragment of a membrane phosphoprotein, CD20, which is expressed on the surface of B cells. CD20 receptor is an important target for immunotherapy against B cell lymphoma. Synonyms: B-lymphocyte antigen CD20 (188-196). Grade: >95%. Molecular formula: C46H77N9O12. Mole weight: 948.16. | |
| CD206/MRC1 Antibody [K13P18] | CD206/MRC1 Antibody [K13P18]. Group: Antibodies. Alternative Names: Macrophage mannose receptor 1, MMR, C-type lectin domain family 13 member D, C-type lectin domain family 13 member D-like, Human mannose receptor (hMR), Macrophage mannose receptor 1-like protein 1, CD206, MRC1, CLEC13D, CLEC13DL, MRC1L1. CAS No. Pack Sizes: 20uL. Product ID: F4083. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CD 2314 | CD 2314. Group: Biochemicals. Grades: Purified. CAS No. 170355-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CD 2314 | CD 2314 is a potent and selective RARβ receptor agonist (Kd = 145 and >3760 nM for RARβ and RARα receptors, respectively). Synonyms: CD-2314; CD 2314; CD2314; 5-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-anthracenyl)-3-thiophenecarboxylic acid. Grade: ≥98% by HPLC. CAS No. 170355-37-0. Molecular formula: C23H24O2S. Mole weight: 364.5. | |
| CD235 | CD235 is a structurally similar analogue of CD161, which is a potent and orally bioavailable inhibitor of BET bromodomain. Synonyms: 7-(3,5-Dimethyl-1,2-oxazol-4-yl)-4-(6-fluoro-4-quinolinyl)-6-methoxy-2-methyl-9H-pyrimido[4,5-b]indole; 9H-Pyrimido[4,5-b]indole, 7-(3,5-dimethyl-4-isoxazolyl)-4-(6-fluoro-4-quinolinyl)-6-methoxy-2-methyl-. Grade: ≥95%. CAS No. 1627716-57-7. Molecular formula: C26H20FN5O2. Mole weight: 453.47. | |
| CD2665 | CD2665 is an orally active and selective RAR-β,γ antagonist, with Kd values of 306 nM, 110 nM for RAR-β and RAR-γ, repectively[1][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 170355-78-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-107437. | |
| CD 2665 | CD 2665 is a selective RARβ and RARγ antagonist (KD = 110, 306 and > 1000 nM for RARγ, RARβ and RARα respectively) with no activity at RXRα. CD 2665 is used to abrogate retinoic acid-induced apoptosis, proliferation and differentiation of sebocyte growth. Synonyms: CD2665; CD 2665; CD-2665. 4-[6-[(2-Methoxyethoxy)methoxy]-7-tricyclo[3.3.1.13,7]dec-1-yl-2-naphthalenyl)benzoic acid. Grade: ≥98% by HPLC. CAS No. 170355-78-9. Molecular formula: C31H34O5. Mole weight: 486.6. | |
| CD 2665 | CD 2665. Group: Biochemicals. Grades: Purified. CAS No. 170355-78-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Cd2+-exporting ATPase | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. This enzyme occurs in protozoa, fungi and plants. Group: Enzymes. Enzyme Commission Number: EC 3.6.3.3. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4667; Cd2+-exporting ATPase; EC 3.6.3.3. Cat No: EXWM-4667. |  |
| CD-3 | CD-3 (Part#: 1090) | |
| CD31 (PECAM-1) Antibody [M18G16] | CD31,CD31 (PECAM-1),CD31 / PECAM-1,PECAM-1. Group: Antibodies. Alternative Names: CD31,PECAM-1. Pack Sizes: 20uL. Product ID: F0131. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CD 3254 | CD 3254. Group: Biochemicals. Grades: Purified. CAS No. 196961-43-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CD 3254 | CD 3254 is a selective RXRα agonist with no activity at RARα, RARβ or RARγ receptors. Synonyms: CD3254; CD 3254; CD-3254. 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoic acid. Grade: ≥97% by HPLC. CAS No. 196961-43-0. Molecular formula: C24H28O3. Mole weight: 364.48. | |
| CD33 splicing modulator 1 | CD33 splicing modulator 1 (Compound 1) is a CD33 splicing modulator. CD33/Siglec 3 is a myeloid lineage cell surface receptor that is known to regulate microglia activity. CD33 splicing modulator 1 increases exon 2 skipping in cellular mRNA pools. CD33 splicing modulator 1 has the potential for the research of neurodegenerative disease including Alzheimer's disease[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2762547-05-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144399. | |
| CD34+ Cells Targeted SM102 LNP-EGFP mRNA (m1Ψ) | This product is a LNP prepared from SM102 as the ionizable lipid and modified with CD34 antibody. It's specifically designed for targeted delivery of EGFP mRNA to CD34 positive cells. EGFP mRNA, a common fluorescence reporter, translates into enhanced green fluorescent protein, which exhibits an excitation wavelength of 488 nm and emission at 507 nm. The loaded EGFP mRNA is modified with N1-methyl-pseudouridine to enhance expression and reduce immunogenicity. It is only for research purposes. Group: Lipid nanoparticle. |  |
| CD38 inhibitor 1 | CD38 inhibitor 1 (compound 78c) is a potent CD38 inhibitor with IC50s of 7.3 nM and 1.9 nM for hCD38 and mouse CD38[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1700637-55-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-123999. | |
| CD38 inhibitor 1 | CD38 inhibitor 1 is a potent CD38 inhibitor. Synonyms: CD38-IN-78c; MDK-7553. CAS No. 1700637-55-3. Molecular formula: C22H27N3O3S. Mole weight: 413.53. | |
| CD38 inhibitor 1 (compound 78c) | CD38 inhibitor 1 (compound 78c, CD38-IN-78c, MDK-7553) is a potent inhibitor of CD38 with IC50 of 7.3 nM and 1.9 nM for human CD38 and mouse CD38, respetively. Group: Inhibitors. Alternative Names: CD38-IN-78c, MDK-7553. CAS No. 1700637-55-3. Pack Sizes: 5mg. Product ID: S8960. Formula: C22H27N3O3S. Smiles: CN1C2=C(C=C(C=C2)C3=CN=CS3)C(=CC1=O)NC4CCC(CC4)OCCOC. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| CD39-IN-1 | CD39-IN-1 is a selective CD39 inhibitor with an IC50 value of 68.7 nM. CD39-IN-1 exerts antiproliferative effects on tumor cells and shows low toxicity to normal cell lines. CD39-IN-1 inhibits CD39-mediated eATP hydrolysis in the ATP-adenosine pathway. CD39-IN-1 is applicable for tumor-related research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3097380-98-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-174341. | |
| CD-4 | CD-4 (Part#: 1095) | |
| CD40-TRAF6 inhibitor | A CD40-TRAF6 interaction inhibitor. Synonyms: 3-[(2,5-Dimethylphenyl)amino]-1-phenyl-2-propen-1-one. CAS No. 433249-94-6. Molecular formula: C17H17NO. Mole weight: 251.32. | |
| CD437 | CD437 is a selective Retinoic Acid Receptor γ (RARγ) agonist. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AHPN. CAS No. 125316-60-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100532. | |
| CD 437 | CD 437. Group: Biochemicals. Grades: Purified. CAS No. 125316-60-1. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| CD532 | CD532 is a potent Aurora A kinase inhibitor with an IC50 of 45 nM. CD532 has the dual effect of blocking Aurora A kinase activity and driving degradation of MYCN. CD532 also can directly interact with AURKA and induces a global conformational shift. CD532 can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1639009-81-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-112273. | |
| CD532 hydrochloride | CD532 hydrochloride is a potent Aurora A kinase inhibitor with an IC50 of 45 nM. CD532 hydrochloride has the dual effect of blocking Aurora A kinase activity and driving degradation of MYCN. CD532 hydrochloride can also directly interact with AURKA and induces a global conformational shift. Synonyms: CD532 (hydrochloride); CD532 hydrochloride; EX-A8075A; HY-112273A; MS-30172; CS-0202740; 2926498-81-7. Grade: 99%. Molecular formula: C26H26ClF3N8O. Mole weight: 558.99. | |
| CD59 glycoprotein precursor (106-114) | CD59 glycoprotein precursor (106-114) is a peptide derived from CD59 glycoprotein precursor which is a potent inhibitor of the complement membrane attack complex (MAC) action. CD59 glycoprotein is involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. Synonyms: HRF-20 (106-114); Membrane attack complex inhibition factor (106-114). | |
| CD63 Antibody [N10M7] | CD63 Antibody [N10M7]. Group: Antibodies. CAS No. Pack Sizes: 20uL. Product ID: F0983. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CD68 Antibody [M20C19] | CD68,CD68/SR-D1. Group: Antibodies. Alternative Names: CD68, Macrosialin, Cd68. CAS No. Pack Sizes: 20uL. Product ID: F3794. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CD73-IN-1 | CD73-IN-11 is a CD73 inhibitor with an IC50 of ≤316.23 nM for the human enzyme in a cell-free assay. It can be used in cancer treatment. (Extracted from patent WO 2017153952 A1, example 80). Synonyms: VPS34 inhibitor; 5-[N-(2-Cyclopropyl-6-indolyl)sulfamoyl]-2-hydroxybenzamide; CD73 inhibitor 1; Benzamide, 5-[[(2-cyclopropyl-1H-indol-6-yl)amino]sulfonyl]-2-hydroxy-. Grade: ≥98%. CAS No. 2132396-40-6. Molecular formula: C18H17N3O4S. Mole weight: 371.41. | |
| CD73-IN-2 | CD73-IN-2 is a potent CD73 inhibitor with an IC50 of 0.09 nM. Synonyms: ((((2R,3S,4R,5R)-5-((6-chloro-4-(cyclopentylamino)-1H-pyrazolo[3,4-d]pyrimidin-1-yl)methyl)-3,4-dihydroxytetrahydrofuran-2-yl)methoxy)methyl)phosphonic acid. Molecular formula: C17H25ClN5O7P. Mole weight: 477.84. | |
| CD73-IN-4 | CD73-IN-4 is a potent and selective methylenephosphonic acid CD73 inhibitor with an IC50 of 2.6 nM for human. It has potential in cancer immunology research. Synonyms: 1H-Pyrazolo[3,4-d]pyrimidin-4-amine, 6-chloro-N-cyclopentyl-1-[5-O-(phosphonomethyl)-β-D-ribofuranosyl]-; 6-Chloro-N-cyclopentyl-1-[5-O-(phosphonomethyl)-β-D-ribofuranosyl]-1H-pyrazolo[3,4-d]pyrimidin-4-amine. Grade: ≥97%. CAS No. 2216764-29-1. Molecular formula: C16H23ClN5O7P. Mole weight: 463.81. | |
| CD73-IN-5 | CD73-IN-5 is a potent and selective non-nucleotide small molecule CD73 inhibitor with an IC50 of 19 nM. Synonyms: Benzonitrile, 4-[[5-[4-fluoro-1-(1H-indazol-6-yl)-1H-benzotriazol-6-yl]-1H-pyrazol-1-yl]methyl]-. CAS No. 2412019-99-7. Molecular formula: C24H15FN8. Mole weight: 434.43. | |
| CD9 Antibody [J21F10] | CD9 Antibody [J21F10]. Group: Antibodies. Pack Sizes: 20ul. Product ID: F1178. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| CDAP | CDAP is an organic cyanylating reagent that can be used for preparation of solid phase affinity reagents, modification of protein thiols and nucleotide delivery. CDAP also activates polysaccharides with a variety of chemical properties. CDAP can be used to prepare conjugate vaccines and other immune reagents[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 59016-56-7. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W012184. | |
| Cdc25A (80-93) (human) | Cdc25A abundance fluctuates periodically during the cell division cycle and is mainly regulated by the ubiquitin-proteasome system, through the action of two ubiquitin ligase complexes, which later promote complex/cyclosome and Skp1/Cul1/F-box proteins. Due to the presence of the destruction motif (KEN-box) in Cdc25A, ubiquitination and degradation occur at the mitotic outlet and G1, while phosphorylation events modulate the stability of Cdc25A protein in the S phase, both in undisturbed cells and in cells exposed to DNA damage agents or DNA replication inhibitors. Synonyms: H-Thr-Asp-Ser-Gly-Phe-Cys-Leu-Asp-Ser-Pro-Gly-Pro-Leu-Asp-OH. Grade: ≥95%. CAS No. 851538-67-5. Molecular formula: C60H90N14O24S. Mole weight: 1423.52. | |
| Cdc7-IN-1 | Cdc7-IN-1 (Compound 13) is a highly potent, selective and ATP competitive inhibitor of Cdc7 kinase, with an IC50 value of 0.6 nM at 1 mM ATP and with slow off-rate characteristics. Cdc7-IN-1 potently inhibits Cdc7 activity in cancer cells, and effectively induces cell death[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1402055-25-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101523. | |
| Cdc7-IN-1 | Cdc7-IN-1 is a highly potent, selective and ATP competitive Cdc7 kinase inhibitor, with an IC50 of 0.6 nM at 1 mM ATP and a slow deceleration characteristic. It can effectively inhibit the activity of Cdc7 in cancer cells and induce cell death. Synonyms: Ethyl (5Z)-2-[(2-chlorophenyl)amino]-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 2-[(2-chlorophenyl)amino]-4,5-dihydro-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-, ethyl ester, (5Z)-. Grade: ≥99%. CAS No. 1402055-25-7. Molecular formula: C21H16ClN3O4. Mole weight: 409.82. | |
| Cdc7-IN-3 | Cdc7-IN-3, a potent inhibitor of Cdc7 kinase, is a serine-threonine protein kinase enzyme that is required for the initiation of DNA replication during the cell cycle. (Extracted from patent WO2019165473A1, compound I-B). Synonyms: Isopropyl (5Z)-2-(4-morpholinylamino)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 4,5-dihydro-2-(4-morpholinylamino)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-, 1-methylethyl ester, (5Z)-. Grade: ≥95%. CAS No. 1402057-87-7. Molecular formula: C20H22N4O5. Mole weight: 398.41. | |
| Cdc7-IN-4 | Cdc7-IN-4, a potent inhibitor of Cdc7 kinase, is a serine-threonine protein kinase enzyme that is required for the initiation of DNA replication during the cell cycle. (Extracted from patent WO2019165473A1, compound I-C). Synonyms: Isopropyl (5Z)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-{[4-(2,2,2-trifluoroethyl)-1-piperazinyl]amino}-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 4,5-dihydro-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-[[4-(2,2,2-trifluoroethyl)-1-piperazinyl]amino]-, 1-methylethyl ester, (5Z)-. Grade: ≥97%. CAS No. 1402059-21-5. Molecular formula: C22H24F3N5O4. Mole weight: 479.45. | |
| Cdc7-IN-5 | Cdc7-IN-5, a potent inhibitor of Cdc7 kinase, is a serine-threonine protein kinase enzyme that is required for the initiation of DNA replication during the cell cycle. (Extracted from patent WO2019165473A1, compound I-B). Synonyms: Ethyl (5Z)-2-(7-methoxy-3,4-dihydro-2(1H)-isoquinolinyl)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 2-(3,4-dihydro-7-methoxy-2(1H)-isoquinolinyl)-4,5-dihydro-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-, ethyl ester, (5Z)-. Grade: ≥95%. CAS No. 1402057-86-6. Molecular formula: C25H23N3O5. Mole weight: 445.47. | |
| Cdc7-IN-6 | Cdc7-IN-6 is a potent Cdc7 kinase inhibitor (IC50 = 4 nM) with antitumor activity. (Extracted from patent WO2019165473A1, compound I-D). Synonyms: AS-0141; Ethyl (5Z)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-{[4-(2,2,2-trifluoroethyl)-1-piperazinyl]amino}-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 4,5-dihydro-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-2-[[4-(2,2,2-trifluoroethyl)-1-piperazinyl]amino]-, ethyl ester, (5Z)-. Grade: ≥97%. CAS No. 1402057-88-8. Molecular formula: C21H22F3N5O4. Mole weight: 465.43. | |
| Cdc7-IN-7 | Cdc7-IN-7, a potent inhibitor of Cdc7 kinase, is a serine-threonine protein kinase enzyme that is required for the initiation of DNA replication during the cell cycle. (Extracted from patent WO2019165473A1, compound I-E). Synonyms: Cyclopropylmethyl (5Z)-2-(4-morpholinylamino)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-4,5-dihydro-3-furancarboxylate; 3-Furancarboxylic acid, 4,5-dihydro-2-(4-morpholinylamino)-4-oxo-5-(1H-pyrrolo[2,3-b]pyridin-3-ylmethylene)-, cyclopropylmethyl ester, (5Z)-. Grade: ≥97%. CAS No. 1402059-17-9. Molecular formula: C21H22N4O5. Mole weight: 410.42. | |
| CDC801 | A potent, orally active and dual inhibitor of phosphodiesterase 4 (PDE4) (IC50= 1.1 μM) and tumor necrosis factor-α (TNF-α) (IC50= 2.5 μM). Synonyms: CDC801; CDC 801; CDC-801; 3-(3-cyclopentyloxy-4-methoxyphenyl)-3-(1,3-dioxoisoindol-2-yl)propanamide. CAS No. 192819-27-5. Molecular formula: C23H24N2O5. Mole weight: 408.45. | |
| CDD0102 | CDD0102 is a selective M1 agonist which stimulated the secretion of APP from CHO-K1 cells expressing M1 receptors and penetrated into the brain following i.p. administration in rodents. Synonyms: CDD0102; CDD 0102; CDD-0102; 3-ethyl-5-(1,4,5,6-tetrahydropyrimidin-5-yl)-1,2,4-oxadiazole; 5-(3-ethyl-1,2,4-oxadiazol-5-yl)-1,4,5,6-tetrahydropyrimidine; CDD-0102A. CAS No. 146422-58-4. Molecular formula: C8H12N4O. Mole weight: 180.21. | |
| CDD-1653 | CDD-1653 is a potent and selective BMPR2 inhibitor (IC50=2.8 nM). CDD-1653 reduces the ability of ATP to bind to the kinase domain of BMPR2, thereby affecting the phosphorylation of SMAD1/5/8 transcription factors, which play a key role in the BMP signaling pathway. CDD-1653 can be used to study diseases related to the BMP signaling pathway[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3034216-44-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-164145. | |
| CDD-2789 | CDD-2789 is a potent and selective ALK2 inhibitor with an IC50 0.54 μM and a Kd of 2.1 nM, respectively. CDD-2789 exhibits >120-fold selectivity over ALK3/5/6. CDD-2789 reduces activin A- and BMP2-induced SMAD1/5 phosphorylation in fibroblasts. CDD-2789 can be used for ALK2-related cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3052084-77-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-173149. | |
| CDD-2807 | CDD-2807 is an inhibitor for serine/threonine kinase 33 (STK33) with IC50 of 9.2 nM. CDD-2807 exhibits no significant toxicity in mice and can cross the blood-testis barrier without accumulating in the brain. CDD-2807 induces a reversible contraceptive effect and has potential for the development of the male contraceptive[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3086536-23-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162565. | |
| CDD3505 | CDD3505 is an inducer of hepatic cytochrome P450IIIA (CYP3A) activity that elevates high density lipoprotein cholesterol (HDL). Uses: Cytochrome p-450 enzyme inhibitors. Synonyms: 4-Nitro-1-trityl-1H-imidazole; 1-Trityl-4-nitroimidazole. CAS No. 173865-33-3. Molecular formula: C22H17N3O2. Mole weight: 355.39. | |
| CDDD3602 | Tematropium, a neurological agent, is a soft anticholinergic drug. Synonyms: Tematropium; HGP6; Tematropium methylsulfate; Tematropium metilsulfate; 3alpha-Hydroxy-8-methyl-1alphaH,5alphaH-tropanium methyl sulfate (salt), (±)-ethyl hydrogen phenylmalonate; 8-Azoniabicyclo(3.2.1)octane, 3-(3-ethoxy-1,3-dioxo-2-phenylpropoxy)-8,8-dimethyl-, endo-(±)-, methyl sulfate; (3-endo)-3-[(3-Ethoxy-3-oxo-2-phenylpropanoyl)oxy]-8,8-dimethyl-8-azoniabicyclo[3.2.1]octane methyl sulfate. Grade: ≥95%. CAS No. 113932-41-5. Molecular formula: C21H31NO8S. Mole weight: 457.54. | |
| CDDO-2-P-Im | CDDO-2-P-Im is an orally active inhibitor of necroptosis. Synonyms: CDDO-2P-Im. Grade: 98%. CAS No. 1883650-96-1. Molecular formula: C39H46N4O3. Mole weight: 618.8. | |
| CDDO-3-P-Im | CDDO-3-P-Im is an orally active inhibitor of necroptosis. Synonyms: CDDO-3P-Im. Grade: 98%. CAS No. 1883650-95-0. Molecular formula: C39H46N4O3. Mole weight: 618.8. | |
| CDDO-biotin | CDDO-biotin is an IKKβ inhibitor with cancer cell inhibitory activity. CDDO-biotin directly interacts with and oxidizes Cys-179 in the activation loop of IKKβ, forming an adduct with wild-type IKKβ. CDDO-biotin can be used in the research of myeloid leukemia, osteosarcoma, multiple myeloma, lung cancer, breast cancer and pancreatic cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3110422-01-7. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-186167. | |
| CDDO-dhTFEA | CDDO-dhTFEA (RTA dh404) is a synthetic oleanane triterpenoid compound which potently activates Nrf2 and inhibits the pro-inflammatory transcription factor NF-κB[1]. CDDO-dhTFEA restores hypertension (MAP), increases Nrf2 and expression of its target genes, attenuates activation of NF-κB and transforming growth factor-β pathways, and reduces glomerulosclerosis, interstitial fibrosis and inflammation in the chronic kidney disease (CKD) rats[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RTA dh404. CAS No. 1191265-33-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112671. | |
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