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| Product | Description | |
|---|---|---|
| Efinaconazole Impurity 57 | Efinaconazole Impurity 57. Uses: For analytical and research use. Alternative Names: (2R,3S)-3-(2,5-difluorophenyl)-3-hydroxy-2-methyl-4-(1H-1,2,4-triazol-1-yl)butanenitrile. CAS No. 2069200-13-9. Molecular formula: C13H12F2N4O. Mole weight: 278.26. Catalog: APB2069200139. |  |
| Efinaconazole Impurity 58 | Efinaconazole Impurity 58. Uses: For analytical and research use. CAS No. 241479-73-2. Molecular formula: C12H11F2N3O. Mole weight: 251.24. Catalog: APB241479732. | |
| Efinaconazole Impurity 58 | Efinaconazole Impurity 58. Uses: For analytical and research use. Alternative Names: tert-butyl methanesulfonate. CAS No. 16427-41-1. Molecular formula: C5H12O3S. Mole weight: 152.21. Catalog: APB16427411. | |
| Efinaconazole Impurity 59 | Efinaconazole Impurity 59. Uses: For analytical and research use. Molecular formula: C14H14F2N6O. Mole weight: 320.3. Catalog: APB07744. | |
| Efinaconazole Impurity 6 | Efinaconazole Impurity 6. Uses: For analytical and research use. Alternative Names: (2S,3S)-2-(2,4-difluorophenyl)-3-(4-methylenepiperidin-1-yl)-1-(1H-1,2,4-triazol-1-yl)butan-2-ol. CAS No. 164650-45-7. Molecular formula: C18H22F2N4O. Mole weight: 348.39. Catalog: APB164650457. | |
| Efinaconazole Impurity 7 | Efinaconazole Impurity 7. Uses: For analytical and research use. Alternative Names: 1-(((2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole. CAS No. 135270-07-4. Molecular formula: C12H11F2N3O. Mole weight: 251.23. Catalog: APB135270074. | |
| Efinaconazole Impurity 8 | Efinaconazole Impurity 8. Uses: For analytical and research use. Alternative Names: 1-(((2S,3S)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole. CAS No. 135270-10-9. Molecular formula: C12H11F2N3O. Mole weight: 251.23. Catalog: APB135270109. | |
| Efinaconazole Impurity 9 | Efinaconazole Impurity 9. Uses: For analytical and research use. Alternative Names: 1-(((3R)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole. CAS No. 135270-13-2. Molecular formula: C12H11F2N3O. Mole weight: 251.23. Catalog: APB135270132. | |
| Efinaconazole-N-oxide | An impurity of Efinaconazole, a triazole antifungal approved to treat fungal infections of the toenails as a topical solution. Synonyms: 1-((2R,3R)-3-(2,4-Difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)-4-methylenepiperidine 1-oxide. CAS No. 2055038-63-4. Molecular formula: C18H22F2N4O2. Mole weight: 364.4. |  |
| Efinaconazole N-Oxide | Efinaconazole N-Oxide. Uses: For analytical and research use. Alternative Names: 1-((2R,3R)-3-(2,4-difluorophenyl)-3-hydroxy-4-(1H-1,2,4-triazol-1-yl)butan-2-yl)-4-methylenepiperidine 1-oxide. CAS No. 2055038-63-4. Molecular formula: C18H22F2N4O2. Mole weight: 364.39. Catalog: APB2055038634. | |
| Efinaconazole Related Impurity 3 | The S,S-enantiomer of Efinaconazole, a medication used to treat toenail infection caused by fungus. Synonyms: ent-Efinaconazole; (2S,3S)-Efinaconazole; (αS,βS)-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidine ethanol; [S-(R*,R*)]-α-(2,4-Difluorophenyl)-β-methyl-4-methylene-α-(1H-1,2,4-triazol-1-ylmethyl)-1-piperidine ethanol. Grade: > 95%. CAS No. 164650-45-7. Molecular formula: C18H22F2N4O. Mole weight: 348.39. | |
| Efinaconazole Related Impurity 4 | An enantiomer of Efinaconazole, a triazole antifungal approved to treat fungal infections of the toenails as a topical solution. Synonyms: Efinaconazole 2S,3R Epoxy triazole; 1-(((2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole; 1-{[(2S,3R)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl]methyl}-1H-1,2,4-triazole; (2S,3R)-2-(2,4-difluorophenyl)-3-methyl-2-(1H-1,2,4-triazol-1-yl)methyloxirane. Grade: > 95%. CAS No. 135270-07-4. Molecular formula: C12H11F2N3O. Mole weight: 251.24. | |
| Efinaconazole THP DIOL (2R,3R) | An impurity of Efinaconazole, a triazole antifungal approved to treat fungal infections of the toenails as a topical solution. Grade: 95%. CAS No. 135133-23-2. Molecular formula: C17H21F2N3O3. Mole weight: 353.36. | |
| Efineptakin alfa | Efineptakin alfa (NT-17) is a long-acting recombinant human IL-7. Efineptakin alfa supports the proliferation and survival CD4+ and CD8+ cells in both human and mice. Efineptakin alfa can be used for glioblastoma research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NT-17. CAS No. 2026634-47-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99908. |  |
| Eflepedocokin alfa | Eflepedocokin alfa is a recombinant fusion protein. Eflepedocokin alfa consists of human IL-22 fused to human IgG2-Fc domain. Eflepedocokin alfa leads to the activation of IL-22/IL-22R-mediated signal transduction pathways as well as STAT3. Eflepedocokin alfa plays a role in immune response and bacterial infection, enhancing intestinal barrier function, intestinal immunity, and tissue repair[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: F-652; rhIL-22 dimer. CAS No. 2200269-84-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99917. | |
| Eflornithine | Eflornithine is a difluoromethylated ornithine compound with antineoplastic activity. Eflornithine irreversibly inhibits ornithine decarboxylase, an enzyme required for polyamine biosynthesis, thereby inhibiting the formation and proliferation of tumor cells. Polyamines are involved in nucleosome oligomerization and DNA conformation, creating a chromatin environment that stimulates neoplastic transformation of cells. This agent has been shown to induce apoptosis in leiomyoma cells. Synonyms: Ornithine, 2-(difluoromethyl)-; 2-(Difluoromethyl)ornithine; 2-(Difluoromethyl)-DL-ornithine; DL-2-(Difluoromethyl)ornithine; DL-α-(Difluoromethyl)ornithine; DFMO; DFMO (growth regulator); Difluromethylornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α,δ-Diamino-α-(difluoromethyl)valeric acid; α-(Difluoromethyl)-DL-ornithine; α-(Difluoromethyl)ornithine. Grade: ≥95%. CAS No. 70052-12-9. Molecular formula: C6H12F2N2O2. Mole weight: 182.17. | |
| Eflornithine | Eflornithine is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DFMO; MDL71782; RMI71782; α-difluoromethylornithine. CAS No. 70052-12-9. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-B0744. | |
| Eflornithine | Eflornithine (DFMO) is a selective and orally available ornithine decarboxylase inhibitor that delays hair overgrowth.Eflornithine is used in the study of African trypanosomiasis, malignant glioma, and sleeping sickness. Category: Active pharmaceutical ingredients. CAS No. 70052-12-9. Product ID: API70052129. Molecular formula: C6H12F2N2O2. Mole weight: 182.17. |  |
| Eflornithine (DFMO) Hydrochloride Hydrate | Eflornithine (DFMO) hydrochloride hydrate inhibits polyamine biosynthesis by the selective, irreversible inhibition of ornithine decarboxylase (ODC). A chemoprotective agent that blocks angiogenesis. Its biological half-life is 8 hours. Group: Inhibitors. Alternative Names: Difluoromethylornithine hydrochloride hydrate, MDL-71782 hydrochloride hydrate, RMI-71782 hydrochloride hydrate, α-difluoromethylornithine hydrochloride hydrate. CAS No. 96020-91-6. Pack Sizes: 100mg. Product ID: S4582. Formula: C6H12F2N2O2.HCl.H2O. Smiles: C(CC(C(F)F)(C(=O)O)N)CN.O.Cl. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Eflornithine hydrochloride | Eflornithine hydrochloride, a specific and irreversible inhibitor of ornithine decarboxylase enzyme, is a medication used for the treatment of African trypanosomiasis and excessive facial hair growth in women. Category: Active pharmaceutical ingredients. CAS No. 68278-23-9. Product ID: API68278239. Molecular formula: C6H13ClF2N2O2. Mole weight: 218.63. | |
| Eflornithine hydrochloride | Eflornithine hydrochloride is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. Synonyms: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; MDL 71782 hydrochloride; RMI 71782 hydrochloride; MDL-71782 hydrochloride; RMI-71782 hydrochloride; α-difluoromethylornithine hydrochloride; Vaniqa hydrochloride. Grade: >98%. CAS No. 68278-23-9. Molecular formula: C6H13ClF2N2O2. Mole weight: 218.63. | |
| Eflornithine hydrochloride | Eflornithine hydrochloride is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DFMO hydrochloride; MDL71782 hydrochloride; RMI71782 hydrochloride; α-difluoromethylornithine hydrochloride. CAS No. 68278-23-9. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg. Product ID: HY-B0744A. | |
| Eflornithine hydrochloride | Eflornithine hydrochloride. Group: Biochemicals. Alternative Names: DFMO; DL-2-(Difluoromethyl)-ornithine hydrochloride. Grades: Highly Purified. CAS No. 68278-23-9. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C6H12F2N2O2·HCl. US Biological Life Sciences. |  Worldwide |
| Eflornithine hydrochloride hydrate | Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific, irreversible inhibitor of the enzyme ornithine decarboxylase. Eflornithine hydrochloride hydrate is a medication for the treatment of African trypanosomiasis and excessive facial hair growth in women[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate. CAS No. 96020-91-6. Pack Sizes: 10 mM * 1 mL in Water; 100 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0744B. | |
| Eflornithine hydrochloride hydrate | Eflornithine hydrochloride hydrate (DFMO hydrochloride hydrate) is a specific and irreversible inhibitor of theornithine decarboxylase (ODC). Category: Active pharmaceutical ingredients. Synonyms: Difluoromethylornithine hydrochloride hydrate, α-difluoromethylornithine hydrochloride hydrate, Eflornithine hydrochloride, MDL-71782 hydrochloride hydrate, DFMO hydrochloride hydrate, RMI-71782 hydrochloride hydrate, Eflornithine hydrochloride Monohydrate. CAS No. 96020-91-6. Product ID: API96020916. Molecular formula: C6H15ClF2N2O3. Mole weight: 236.64. | |
| Eflornithine hydrochloride, hydrate | Eflornithine hydrochloride, hydrate is a drug found to be effective in the treatment of facial hirsutism. It is a "suicide inhibitor," irreversibly binding to Ornithine Decarboxylase (ODC) and preventing the natural substrate ornithine from accessing the active site. It is an irreversible inhibitor of ornithine decarboxylase that suppresses polyamine biosynthesis. It displays antiangiogenic and cytostatic effects in tumor cells but must be used in combination with other chemotherapeutic agents to negate compensatory increases in polyamine content through alternate synthesis pathways. It also demonstrates antiparasitic activity in a model of C. parvum infection. Synonyms: DFMO hydrochloride hydrate; MDL-71782 hydrochloride hydrate; RMI-71782 hydrochloride hydrate; MDL 71782 hydrochloride hydrate; RMI 71782 hydrochloride hydrate; MDL71782 hydrochloride hydrate; RMI71782 hydrochloride hydrate; α-difluoromethylornithine hydrochloride hydrate; Vaniqa hydrochloride hydrate. Grade: 98%. CAS No. 96020-91-6. Molecular formula: C6H15ClF2N2O3. Mole weight: 236.64. | |
| Eflornithine Hydrochloride Monoydrate | Irreversible inhibitor of ornithine decarboxylase, an enzyme involved in polyamine biosynthesis. Antineoplastic; antipneumocystic; antiprotozoal (Trypanosoma). Used in the treatment of hirsutism. Group: Biochemicals. Alternative Names: 2-(Difluoromethyl)-DL-ornithine Hydrochloride Hydrate; 2- (Difluoromethyl) ornithine; DFMO; DL-2- (Difluoromethyl) ornithine; DL-α - (Difluoromethyl) ornithine; Elfornithine; MDL 71782; MDL 71782A; Ornidyl; RFI 71782; RMI 71782; α , δ -Diamino-α - (difluoromethyl) valeric Acid; α-(Difluoromethyl)-DL-ornithine; α - (Difluoromethyl) ornithine. Grades: Highly Purified. CAS No. 96020-91-6. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C?H??ClF?N?O?, Molecular Weight: 236.64. US Biological Life Sciences. | Worldwide |
| Efloxate | Efloxate, a flavone derivative, could be effective in the treatment of chronic coronary insufficiency and angina pectoris for acting as a vasodilator. Uses: Efloxate could be effective in the treatment of chronic coronary insufficiency and angina pectoris for acting as a vasodilator. Synonyms: RE 1-0185; RE-1-0185; RE1-0185; efloxate; EFLOXATE/EFLOXATEM; Corosamin; Domucor; Eflocor; Oxyflavyl; Recordil; 2-(4-keto-2-phenyl-chromen-7-yl)oxyacetic acid ethyl ester. Grade: 98%. CAS No. 119-41-5. Molecular formula: C19H16O5. Mole weight: 324.33. | |
| Eflucimibe | Eflucimibe (F 12511) is a new acyl-coenzyme A cholesterol O-acyltransferase (ACAT) inhibitor. Eflucimibe can be used in the research of atherosclerosis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: F 12511. CAS No. 202340-45-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19286. | |
| Efmarodocokin alfa | Efmarodocokin alfa is a fusion protein of human IL-22 and the IgG4 crystallizable fragment. Efmarodocokin alfa activates IL-22 signaling. Efmarodocokin alfa can be used for the research of severe COVID-19 pneumonia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2247840-74-8. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99919. | |
| EFONIDIPINE | Efonidipine could be effective in the treatment of cardiovascular disease as a blocker of T-type and L-type calcium channels. It could also present as the hydrochloride salt form. Uses: Efonidipine could be effective in the treatment of cardiovascular disease as a blocker of t-type and l-type calcium channels. Synonyms: NZ-105; NZ 105; NZ105; Efonidipine; Efonidipine[INN]; 111011-63-3; C34H38N3O7P; Efonidipine(INN); Landel. Grade: 95%. CAS No. 111011-63-3. Molecular formula: C34H38N3O7P. Mole weight: 631.66. | |
| EFONIDIPINE HCL | The hydrochloride salt form of Efonidipine which could be effective in the treatment of cardiovascular disease as a blocker of T-type and L-type calcium channels. Uses: The hydrochloride salt form of efonidipine which could be effective in the treatment of cardiovascular disease as a blocker of t-type and l-type calcium channels. Synonyms: EFONIDIPINE HCL; Efonidipine hydrochloride. Grade: 95%. CAS No. 111011-53-1. Molecular formula: C34H38N3O7P.HCl. Mole weight: 668.12. | |
| Efonidipine hydrochloride monoethanolate | The hydrochloride monoethanolate salt form of Efonidipine which has been launched for hypertension and discontinued for cerebrovascular disorders. Uses: The hydrochloride monoethanolate salt form of efonidipine which has been launched for hypertension and discontinued for cerebrovascular disorders. Synonyms: Efonidipine hydrochloride ethanol; Efonidipine hydrochloride ethanolate; NZ 105 ethanolate; NZ105 ethanolate; NZ-105 ethanolate; EFONIDIPINE HYDROCHLORIDE MONOETHANOLATE; 111011-76-8; Efonidipine.HCl ethanolate. Grade: >98%. CAS No. 111011-76-8. Molecular formula: C36H45ClN3O8P. Mole weight: 631.66. | |
| Efonidipine hydrochloride monoethanolate | Efonidipine (NZ-105) hydrochloride monoethanolate is an orally active dual L-type and T-type calcium channel blocker (CCB) with IC50 values of 1.8 and 350 nM, respectively. Efonidipine hydrochloride monoethanolate inhibits SARS-CoV-2 main protease. Efonidipine hydrochloride monoethanolate modulates adrenal steroidogenesis by increasing the expression of steroidogenic acute regulatory protein (StAR), dbcAMP-or angiotensin II-induced StAR mRNA expression and DHEA-S production, while suppressing the biosynthesis of aldosterone and cortisol. Efonidipine hydrochloride monoethanolate reduces plasma aldosterone levels in vivo. Efonidipine hydrochloride monoethanolate improves cardiac function in heart failure models by inhibiting T-type calcium channels (via both tonic and use-dependent blockade), independently of blood pressure reduction. Efonidipine hydrochloride monoethanolate can be used for research in hypertension, heart failure, and disorders involving dysregulated steroid hormone synthesis[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: NZ-105 hydrochloride monoethanolate; (±)-Efonidipine hydrochloride monoethanolate. CAS No. 111011-76-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12502A. | |
| Efonidipine hydrochloride monoethanolate | Efonidipine hydrochloride monoethanolate. Group: Biochemicals. Grades: Purified. CAS No. 111011-76-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Efpeglenatide | Efpeglenatide is a long-acting glucagon-like peptide-1 receptor agonist (GLP-1RA). Efpeglenatide has been developed as an injection for type 2 diabetes mellitus (T2DM). Synonyms: efpeg. CAS No. 1296200-77-5. | |
| Efprezimod alfa | Efprezimod alfa (MK 7110; CD24 Fc) is a humanized CD24-Fc fusion protein. Efprezimod alfa enhances the interaction between CD24 and Siglec-10, thereby regulating the response of innate immune cells to damage-associated molecular patterns, inhibiting the activation of antigen-presenting cells and subsequent inflammatory responses. Efprezimod alfa is applicable to the research of acute graft-versus-host disease and acquired immunodeficiency syndrome[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK 7110; CD24 Fc. CAS No. 2574508-57-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99928. | |
| Efrotomycin | It is produced by the strain of Streptomyces lavendulae. The combination of Efrotomycin with the prolonging factor Tu inhibits protein biosynthesis. It has anti-gram-positive bacteria and negative bacteria activity, and it can inhibit coccidiosis in mice and chickens and promote the growth of pigs. Synonyms: Producil; Antibiotic FR 02A; Efrotomicina; Efrotomycine; Mocimycin, 31-O-(6-deoxy-4-O-(6-deoxy-2,4-di-O-methyl-alpha-L-mannopyranosyl)-3-O-methyl-beta-D-allopyranosyl)-1-methyl-. CAS No. 56592-32-6. Molecular formula: C59H88N2O20. Mole weight: 1145.33. | |
| Efruxifermin | Efruxifermin is an Fc-FGF21 fusion protein (human IgG1 Fc domain linked to a modified human FGF21). Efruxifermin has prolonged half-life and enhanced receptor affinity compared with native human FGF21. Efruxifermin can be used for the research of non-alcoholic steatohepatitis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AKR-001; AMG-876. CAS No. 2375240-92-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99930. | |
| EFSLVVVRYPQYGVG | EFSLVVVRYPQYGVG. Synonyms: Glu-Phe-Ser-Leu-Val-Val-Val-Arg-Tyr-Pro-Gln-Tyr-Gly-Val-Gly. Molecular formula: C81H121N19O22. Mole weight: 1712.97. | |
| eFT-508 | eFT-508 is a selective inhibitor of MNK1/2 (IC50s = 2.4 nM and 1 nM respectively) inhibiting MNK1/2-mediated signaling and the phosphorylation of certain regulatory proteins. It acts against tumor. Synonyms: SCHEMBL17362622; AKOS030627405; ZINC575623807; CS-5841; CS 5841; CS5841; 6-[(6-aminopyrimidin-4-yl)amino]-8-methylspiro[2H-imidazo[1,5-a]pyridine-3,1'-cyclohexane]-1,5-dione; eFT508. Grade: 98%. CAS No. 1849590-01-7. Molecular formula: C17H20N6O2. Mole weight: 340.38. | |
| Eftansomatropin alfa | Eftansomatropin alfa (GX-H9) is a fusion protein composed of rhGH (growth hormone) and immunoglobulin fragments. In Eftansomatropin alfa, rhGH is fused to a hybrid Fc domain comprising sequences of both IgD and IgG4. Eftansomatropin alfa can be used for the study of growth hormone deficiency (GHD)[1]. Uses: Scientific research. Category: Inhibitory antibodies. Alternative Names: TJ-101; GX-H9; hGH-hyFc; HL-2356. CAS No. 1905448-17-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P99932. | |
| EFTEVYEFDFKYDAPD-NH2 | EFTEVYEFDFKYDAPD-NH2. Synonyms: H-Glu-Phe-Thr-Glu-Val-Tyr-Glu-Phe-Asp-Phe-Lys-Tyr-Asp-Ala-Pro-Asp-NH2. | |
| Eftozanermin alfa | Eftozanermin alfa (ABBV-621) is a tumor necrosis factor-related apoptosis-inducing ligand receptor (TRAIL-R) agonist. Eftozanermin alfa is a fusion protein consisting of a mutant immunoglobulin G1-Fc linked to 2 single-chain trimers of TRAIL. Eftozanermin alfa induces apoptosis in tumor cells by activation of death receptors (DR4 receptor and DR5 receptor) with Kds of 780 nM and 635 nM. Eftozanermin alfa can be used for the research of multiple solid and heme malignancies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ABBV-621. CAS No. 1820660-69-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99934. | |
| EFTUD2 (668-677) | EFTUD2 is required for pre-mRNA splicing as component of the spliceosome, including pre-catalytic, catalytic and post-catalytic spliceosomal complexes. Synonyms: Elongation Factor Tu GTP Binding Domain Containing 2 (668-677); 116 KDa U5 Small Nuclear Ribonucleoprotein Component (668-677); Elongation Factor Tu GTP-Binding Domain-Containing Protein 2 (668-677). | |
| Efungumab | Efungumab is a human recombinant monoclonal antibody with antifungal activity. Efungumab binds to HSP 90, preventing a conformational change needed for fungal viability. Efungumab has the potential for the treatment of invasive candidiasis. Grade: 95%. CAS No. 762260-74-2. | |
| EG 00229 | EG 00229 is a neuropilin 1 (NRP1) receptor antagonist, inhibiting VEGFA binding to the NRP1 b1 domain. Synonyms: EG00229; EG-00229; EG 00229; N2-[[3-[(2,1,3-Benzothiadiazol-4-ylsulfonyl)amino]-2-thienyl]carbonyl]-L-arginine. Grade: ≥98% by HPLC. CAS No. 1018927-63-3. Molecular formula: C17H19N7O5S3. Mole weight: 497.57. | |
| EG 00229 | EG 00229. Group: Biochemicals. Grades: Purified. CAS No. 1018927-63-3. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| EG00229 trifluoroacetate | EG00229 is a neuropilin 1 (NRP1) receptor antagonist. EG00229 selectively inhibits VEGF-A binding to NRP1 b1 domain with an IC50 of 3 μM, but has no effect on VEGFA binding to VEGFR-1 and VEGFR-2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1210945-69-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-10799. | |
| EG 00229 Trifluoroacetate | EG00229 is a small molecule inhibitor of neuropilin-1(Nrp1) with an IC50 of 3μM. EG00229 has been reported to inhibit VEGF-A binding to PAE/NRP1 in the Nrp1and bt-VEGF-A binding to purified Nrp1 b1 domain in a cell-free assay with an IC50 value of 8μM and 3μM, respectively. In addition, EG00229 has also shown the inhibition of VEGF-A binding to VEGFR2, VEGFR1 and Nrp1 in human umbilical vein endothelial cells (HUVECs) in a dose-dependent manner with an IC50 value of 23μM [1]. Besides, EG00229 has been revealed to prevent tuftsin binding to the Nrp1 which is at the cell surface. Moreover, EG00229 has been noted to suppress the anti-inflammatory M2 shift in microglia induced by tuftsin and thus potently prevent tuftsin's action. Synonyms: EG 00229; EG-00229. Grade: >98%. CAS No. 1210945-69-9. Molecular formula: C19H20F3N7O7S3. Mole weight: 611.6. | |
| EG-011 | EG-011 is the first-in-class and potent Wiskott-Aldrich syndrome protein (WASP) activator. EG-011 activates the auto-inhibited form of WASP with strong actin polymerization. EG-011 has selective anti-tumor activity in lymphomas[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2377113-41-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148683. | |
| EG01377 | EG01377 is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1. EG01377 has antiangiogenic, antimigratory, and antitumor effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2227996-00-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-112151. | |
| EG01377 | EG01377 is a potent, bioavailable and selective neuropilin-1 (NRP1) inhibitor, with a Kd of 1.32 μM, and IC50s of both 609 nM for NRP1-a1 and NRP1-b1. It has antiangiogenic, antimigratory and antitumor effects. Synonyms: (3-((5-(4-(aminomethyl)phenyl)-2,3-dihydrobenzofuran)-7-sulfonamido)thiophene-2-carbonyl)-L-arginine; N2-({3-[({5-[4-(Aminomethyl)phenyl]-2,3-dihydro-1-benzofuran-7-yl}sulfonyl)amino]-2-thienyl}carbonyl)-N5-(diaminomethylene)-L-ornithine. Grade: ≥98%. CAS No. 2227996-00-9. Molecular formula: C26H30N6O6S2. Mole weight: 586.68. | |
| EG01377 dihydrochloride | EG01377 dihydrochloride is a potent, bioavailable and selective neuropilin-1 (NRP1) inhibitor, with a Kd of 1.32 μM, and IC50s of 609 nM for both NRP1-a1 and NRP1-b1. It has antiangiogenic, antimigratory and antitumor effects. Synonyms: N2-({3-[({5-[4-(Aminomethyl)phenyl]-2,3-dihydro-1-benzofuran-7-yl}sulfonyl)amino]-2-thienyl}carbonyl)-N5-(diaminomethylene)-L-ornithine dihydrochloride; L-Ornithine, N2-[[3-[[[5-[4-(aminomethyl)phenyl]-2,3-dihydro-7-benzofuranyl]sulfonyl]amino]-2-thienyl]carbonyl]-N5-(diaminomethylene)-, hydrochloride (1:2). Grade: ≥98%. Molecular formula: C26H32Cl2N6O6S2. Mole weight: 659.60. | |
| EG01377 dihydrochloride | EG01377 dihydrochloride is a potent, bioavailable and selective inhibitor of neuropilin-1 (NRP1), with a Kd of 1.32 μM, and IC50s of 609 nM for both NRP1-a1 and NRP1-b1. EG01377 dihydrochloride has antiangiogenic, antimigratory, and antitumor effects[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2749438-61-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112151A. | |
| EG1 | EG1 is a specific inhibitor of specific Paired box 2 (Pax2), which targets the DNA binding domain and inhibits embryonic kidney development. CAS No. 693241-54-2. Molecular formula: C22H18N2O5. Mole weight: 390.39. | |
| EG1 | EG1, a specific Pax2 inhibitor, directly binds the paired domain of Pax2 (Kd=1.35-1.5 μM) and inhibits Pax2-DNA interactions. EG1 can inhibit embryonic kidney development, a process directly dependent on Pax2 activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 693241-54-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124838. | |
| EG-2184 | EG-2184 is a Pannexin-1 channel inhibitor. EG-2184 can be used in opioid withdrawal related research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2770297-66-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163905. | |
| Eg5-I | Eg5, also known as KSP and Kif11, is a kinesin-like spindle protein that is essential for establishing a bipolar spindle during mitosis. Eg5-I is a potent inhibitor of Eg5, both in vitro and in cells (IC50s = 127 and 190 nM, respectively). Synonyms: (2R)-2-amino-3-[[(4-methoxyphenyl)diphenylmethyl]thio]-1-propanol. Grade: ≥98%. CAS No. 1338701-15-7. Molecular formula: C23H25NO2S. Mole weight: 379.5. | |
| Eg5 Inhibitor V, trans-24 | Eg5 Inhibitor V, trans-24 is a potent and specific inhibitor of kinesin Eg5 with an IC50 of 0.65 μM. It can be used in cancer research. Synonyms: 1H-Imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione, 5,6,11,11a-tetrahydro-5-(3-hydroxyphenyl)-2-(phenylmethyl)-, (5R,11aS)-; (5R,11aS)-2-Benzyl-5-(3-hydroxyphenyl)-5,6,11,11a-tetrahydro-1H-imidazo[1',5':1,6]pyrido[3,4-b]indole-1,3(2H)-dione; Trans-24. Grade: ≥95%. CAS No. 869304-55-2. Molecular formula: C26H21N3O3. Mole weight: 423.46. | |
| EGA | EGA is an inhibitor of endosomal trafficking. EGA is a small molecule that blocks the entry of anthrax lethal toxin by inhibiting trafficking pathways in acidified endosomes, without affecting endosome pH. It also blocks trafficking of other toxins, except ricin. Synonyms: 2-[(4-bromophenyl)methylene]-N-(2,6-dimethylphenyl)-hydrazinecarboxamide. Grade: ≥98%. CAS No. 415687-81-9. Molecular formula: C16H16BrN3O. Mole weight: 346.2. | |
| EGA | EGA is an inhibitor that selectively targets the endosomal trafficking pathways. EGA targets the proteins involved in the endosomal trafficking pathways through which multiple toxins and viruses enter cells. EGA exerts its activity by inhibiting the trafficking from early endosomes to late endosomes, blocking the entry of multiple acid-dependent bacterial toxins and viruses into mammalian cells and delaying the lysosomal targeting and degradation of EGFR[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 415687-81-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-125168. | |
| Egalognastat | Egalognastat (ASN90) is a selective, brain-penetrant and orally active O-GlcNAcase (OGA) enzyme inhibitor with an IC50 value of 10.2 nM. Egalognastat increases O-GlcNAcylation of intracellular proteins like tau and α-synuclein, preventing their aggregation and toxicity. Egalognastat does not inhibit hexosaminidase (Hex). Egalognastat can be used for the research of neurodegenerative diseases, such as tauopathies and α-synucleinopathies (e.g., Alzheimers disease and Parkinsons disease)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ASN90. CAS No. 1884154-02-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156586. | |
| Eganelisib | Eganelisib (IPI549) is a potent and selective PI3Kγ inhibitor with an IC50 of 16 nM. Eganelisib shows >100-fold selectivity over other lipid and protein kinases[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IPI-549. CAS No. 1693758-51-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-100716. | |
| Eganelisib (IPI-549) | Eganelisib (IPI-549) is a potent inhibitor of PI3K-γ with >100-fold selectivity over other lipid and protein kinases. The biochemical IC50 for PI3K-γ is 16 nM. Group: Inhibitors. CAS No. 1693758-51-8. Pack Sizes: 5mg. Product ID: S8330. Formula: C30H24N8O2. Smiles: CC(C1=CC2=C(C(=CC=C2)C#CC3=CN(N=C3)C)C(=O)N1C4=CC=CC=C4)NC(=O)C5=C6N=CC=CN6N=C5N. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Egaptivon pegol | Egaptivon pegol (ARC1779) is an aptamer, which blocks binding of the von Willebrand Factor (VWF) to platelet GPIb receptors. Egaptivon pegol has anti-thrombotic efficacy. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ARC 1779. CAS No. 934868-74-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-147079. | |
| EGCG ((-)-Epigallocatechin Gallate) | EGCG ((-)-Epigallocatechin Gallate) is the main catechin extraction of green tea that inhibits telomerase and DNA methyltransferase. EGCG blocks the activation of EGF receptors and HER-2 receptors. ECGG inhibits fatty acid synthase and glutamate dehydrogenase activity. Group: Inhibitors. CAS No. 989-51-5. Pack Sizes: 50mg. Product ID: S2250. Formula: C22H18O11. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| EGCG (Epigallocatechin Gallate) | EGCG (Epigallocatechin Gallate). CAS No. 989-51-5. Purity: 50-98%. Product ID: CI-NAT-989515. Molecular formula: C22H18O11. Mole weight: 458.37 g/mol. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| EGCG Octaacetate | EGCG Octaacetate (AcEGCG) is a proagent of Green tea epigallocatechin-3-gallate (EGCG). EGCG Octaacetate decreases the proinflammatory mediator levels by down-regulating of PI3K/Akt/NFκB phosphorylation and p65 acetylation. EGCG octaacetate is the potential antibacterial compound for gram-positive bacteria (GPB) and gram-negative bacteria (GNB). EGCG Octaacetate exhibits antioxidant, anti-angiogenesis, anti-inflammatory and antitumor activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AcEGCG; Peracetylated (-)-epigallocatechin-3-gallate. CAS No. 148707-39-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-N6263. | |
| EGCG Octaacetate | EGCG Octaacetate. Group: Biochemicals. Alternative Names: Pro-epigallocatechin gallate; Peracetylated epigallocatechin-3-gallate; Epigallocatechin Gallate Octaacetate; AcEGCG. Grades: Plant Grade. CAS No. 148707-39-5. Pack Sizes: 20mg. Molecular Formula: C38H34O19, Molecular Weight: 794.671. US Biological Life Sciences. | Worldwide |
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