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Elacestrant , also known as RAD1901, is an orally available, selective estrogen receptor degrader (SERD) and selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Upon oral administration of higher doses of RAD1901, this agent acts as a SERD, which binds to the estrogen receptor (ER) and induces a conformational change that results in the degradation of the receptor. This may inhibit the growth and survival of ER-expressing cancer cells. At lower doses of this agent, RAD1901 acts as a SERM and has estrogen-like effects in certain tissues, which can both reduce hot flashes and protect against bone loss. In addition, RAD1901 is able to cross the blood-brain barrier (BBB). Group: Others. Alternative Names: RAD1901; RAD-1901; RAD 1901; RAD1901 HCl salt; Elacestrant dihydrochloride; Elacestrant HCl. CAS No. 1349723-93-8. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. Appearance: Solid powder. Purity: >98%. IUPACName: (R)-6- (2- (ethyl (4- (2- (ethylamino)ethyl)benzyl)amino)-4-methoxyphenyl)-5, 6, 7, 8-tetrahydronaphthalen-2-ol dihydrochloride. Canonical SMILES: OC1=CC=C2C[C@H] (C3=CC=C (OC)C=C3N (CC4=CC=C (CCNCC)C=C4)CC)CCC2=C1. [H]Cl. [H]Cl. Catalog: ACM1349723938.
Elacestrant S enantiomer
Elacestrant S enantiomer is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Synonyms: RAD1901 S enantiomer; 2-Naphthalenol, 6-[2-[ethyl[[4-[2- (ethylamino) ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5, 6, 7, 8-tetrahydro-, (6S)-; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol. CAS No. 2309762-29-4. Molecular formula: C30H38N2O2. Mole weight: 458.63.
Elacestrant S enantiomer dihydrochloride
Elacestrant S enantiomer dihydrochloride is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Synonyms: RAD1901 S enantiomer dihydrochloride; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol dihydrochloride; 2-Naphthalenol, 6-[2-[ethyl[[4-[2- (ethylamino) ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5, 6, 7, 8-tetrahydro-, (6S)-, hydrochloride (1:2). Grades: ≥95%. CAS No. 2309762-30-7. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56.
Elacridar
Elacridar. Group: Biochemicals. Alternative Names: N-[4-[2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9, 10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918; GG 918. Grades: Highly Purified. CAS No. 143664-11-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C??H??N?O?, Molecular Weight: 563.64. US Biological Life Sciences.
Worldwide
Elacridar
Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Synonyms: GF120918; GF-120918; GF 120918; GF-120918A; GF120918A; GF 120918A; GG 918; D03968. Elacridar hydrochloride. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.654.
A prototypical BCRP inhibitor. Inhibits the Bcrp1-mediated transport. Group: Biochemicals. Alternative Names: N-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl-d4]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918-d4; GG 918-d4; GW 0918-d4. Grades: Highly Purified. CAS No. 1189481-51-3. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Elacridar hydrochloride
Elacridar is an orally bioavailable inhibitor of P-glycoprotein (P-gp) and ABCG2. Synonyms: Elacridar HCl; N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-5-methoxy-9-oxo-10H-acridine-4-carboxamide hydrochloride. CAS No. 143851-98-3. Molecular formula: C34H33N3O5.HCl. Mole weight: 600.10.
P-glycoprotein (P-gp/ABCG1) inhibitor. Blocks P-gp-mediated multidrug resistance (MDR) of the cytotoxic drugs doxorubicin and vincristine in CHRC5 cells. Also inhibits breast cancer resistance protein (BCRP/ABCG2). Orally active. Group: Biochemicals. Grades: Highly Purified. CAS No. 143851-98-3. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Elacytarabine
Elacytarabine (CP 4055) is a lipid-conjugated derivative of the nucleoside analog cytarabine. Elacytarabine (CP 4055) is an antineoplastic agent with cytotoxicity in solid tumors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CP 4055. CAS No. 188181-42-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14941.
Elacytarabine
Elacytarabine (CP-4055) is the lipophilic 5'-elaidic acid ester of the deoxycytidine analog cytosine arabinoside (cytarabine; Ara-C) with potential antineoplastic activity. As a prodrug, CP-4055 is converted intracellularly into cytarabine triphosphate by deoxycytidine kinase and subsequently competes with cytidine for incorporation into DNA, thereby inhibiting DNA synthesis. Compared to cytarabine, CP-4055 shows increased cellular uptake and retention, resulting in increased activation by deoxycytidine kinase to cytarabine triphosphate, decreased deamination and deactivation by deoxycytidine deaminase, and increased inhibition of DNA synthesis. This agent also inhibits RNA synthesis, an effect not seen with cytarabine. Synonyms: CP-4055; CP 4055; CP4055; 5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine; 5'-Oleoyl cytarabine; (E)-((2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate. CAS No. 188181-42-2. Molecular formula: C27H45N3O6. Mole weight: 507.67.
Elafibranor
Elafibranor (GFT505) is a PPARα/δ agonist with EC 50 s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GFT505. CAS No. 923978-27-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16737.
Elafibranor
Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Synonyms: Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid; (E) -1-[4- (Methylthio) phenyl]-3-[3, 5-dimethyl-4-[ (carboxydimethylmethyl) oxy]phenyl]prop-2-en-1-one; GFT 505; GFT-505; GFT505. Grades: ≥95%. CAS No. 923978-27-2. Molecular formula: C22H24O4S. Mole weight: 384.49.
Elagolix
Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultimately reduces circulating sex hormone levels. To date, elagolix has been studied in over 20 clinical trials totaling more than 1,000 subjects. A Phase 2a trial of elagolix for the treatment of uterine fibroids is also ongoing. Endometriosis can be a debilitating disease that affects millions of women around the world and the exploration of new treatments could offer other options for women with this disease. Synonyms: Elagolix, Elagolix sodium, NBI-56418; NBI 56418; NBI56418. CAS No. 834153-87-6. Molecular formula: C32H30F5N3O5. Mole weight: 631.6.
Elagolix
Elagolix. Uses: For analytical and research use. Group: Impurity standards. CAS No. 834153-87-6. Molecular Formula: C32H30F5N3O5. Mole Weight: 631.6. Catalog: APB834153876.
Elagolix Impurity 1
Elagolix Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (R)-4-((2-(3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate. Molecular Formula: C25H24F4N3NaO4. Mole Weight: 529.46. Catalog: APB05845.
Elagolix Impurity 10
Elagolix Impurity 10. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(2-fluoro-3-methoxyphenyl)-6-methyl-1-(2-(trifluoromethyl)benzyl)pyrimidine-2,4(1H,3H)-dione. Molecular Formula: C20H16F4N2O3. Mole Weight: 408.35. Catalog: APB05841.
Elagolix Impurity 11
Elagolix Impurity 11. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(2-fluoro-6-(trifluoromethyl)benzyl)-5-(3-methoxyphenyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C20H16F4N2O3. Mole Weight: 408.35. Catalog: APB05839.
Elagolix Impurity 12
Elagolix Impurity 12. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-N-(2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)-2-hydroxybenzamide. Molecular Formula: C35H28F5N3O5. Mole Weight: 665.61. Catalog: APB05840.
Elagolix Impurity 13
Elagolix Impurity 13. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,2'-difluoro-3,3'-dimethoxy-1,1'-biphenyl. CAS No. 2316733-82-9. Molecular Formula: C14H12F2O2. Mole Weight: 250.24. Catalog: APB2316733829.
Elagolix Impurity 14
Elagolix Impurity 14. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.22. Catalog: APB05838.
Elagolix Impurity 15
Elagolix Impurity 15. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 6-methyl-1-(2-(trifluoromethyl)benzyl)pyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H11F3N2O2. Mole Weight: 284.23. Catalog: APB05837.
Elagolix Impurity 16
Elagolix Impurity 16. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(2-fluoro-4-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.22. Catalog: APB05836.
Elagolix Impurity 17
Elagolix Impurity 17. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(4-fluoro-2-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.22. Catalog: APB05835.
Elagolix Impurity 19
Elagolix Impurity 19. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. CAS No. 2354391-45-8. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.22. Catalog: APB2354391458.
Elagolix Impurity 19Q
Elagolix Impurity 19Q. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2409132-60-9. Molecular Formula: C36H36F5N3O7. Mole Weight: 717.69. Catalog: APB2409132609.
Elagolix Impurity 2
Elagolix Impurity 2. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2409132-64-3. Molecular Formula: C38H40F5N3O6. Mole Weight: 729.75. Catalog: APB2409132643.
Elagolix Impurity 2
Elagolix Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.22. Catalog: APB05844.
Elagolix Impurity 20
Elagolix Impurity 20. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-4,4'-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)azanediyl)dibutanoic acid. Molecular Formula: C36H36F5N3O7. Mole Weight: 717.68. Catalog: APB05833.
Elagolix Impurity 21
Elagolix Impurity 21. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(2-fluoro-4-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.22. Catalog: APB05832.
Elagolix Impurity 22
Elagolix Impurity 22. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)(hydroxy)amino)butanoic acid. Molecular Formula: C32H30F5N3O6. Mole Weight: 647.59. Catalog: APB05834.
Elagolix Impurity 23
Elagolix Impurity 23. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methyl-3-(2-oxo-2-phenylethyl)pyrimidine-2,4(1H,3H)-dione. CAS No. 2409132-61-0. Molecular Formula: C28H21F5N2O4. Mole Weight: 544.47. Catalog: APB2409132610.
Elagolix Impurity 24
Elagolix Impurity 24. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5-chloro-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H9ClF4N2O2. Mole Weight: 336.67. Catalog: APB05831.
Elagolix Impurity 24
Elagolix Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2486454-63-9. Molecular Formula: C32H30F5N3O6. Mole Weight: 647.6. Catalog: APB2486454639.
Elagolix Impurity 25
Elagolix Impurity 25. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-diethyl 4,4'-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)azanediyl)dibutanoate. Molecular Formula: C40H44F5N3O7. Mole Weight: 773.79. Catalog: APB05830.
Elagolix Impurity 26
Elagolix Impurity 26. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (R)-4,4'-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)azanediyl)dibutanoate. Molecular Formula: C36H34F5N3Na2O7. Mole Weight: 761.65. Catalog: APB05829.
Elagolix Impurity 26
Elagolix Impurity 26. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1092070-97-7. Molecular Formula: C33H32F5N3O5. Mole Weight: 645.63. Catalog: APB1092070977.
Elagolix Impurity 27
Elagolix Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-N-(2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)formamide. Molecular Formula: C29H24F5N3O4. Mole Weight: 573.52. Catalog: APB05827.
Elagolix Impurity 28
Elagolix Impurity 28. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methyl-3-(2-(2-oxopyrrolidin-1-yl)-2-phenylethyl)pyrimidine-2,4(1H,3H)-dione. Molecular Formula: C32H28F5N3O4. Mole Weight: 613.59. Catalog: APB05828.
Elagolix Impurity 29
Elagolix Impurity 29. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-4-methyl-2,6-dioxo-3-(2-(trifluoromethyl)benzyl)-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate. Molecular Formula: C32H30F4N3NaO5. Mole Weight: 635.59. Catalog: APB05826.
Elagolix Impurity 3
Elagolix Impurity 3. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2749467-58-9. Molecular Formula: C30H26F5N3O4. Mole Weight: 587.55. Catalog: APB2749467589.
Elagolix Impurity 3
Elagolix Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-4,4'-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)azanediyl)dibutanoic acid. Molecular Formula: C36H36F5N3O7. Mole Weight: 717.68. Catalog: APB05843.
Elagolix Impurity 30
Elagolix Impurity 30. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methyl-3-(2-nitroso-2-phenylethyl)pyrimidine-2,4(1H,3H)-dione. Molecular Formula: C28H22F5N3O4. Mole Weight: 559.49. Catalog: APB05825.
Elagolix Impurity 31
Elagolix Impurity 31. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)(hydroxy)amino)butanoic acid. Molecular Formula: C32H30F5N3O6. Mole Weight: 647.60. Catalog: APB05824.
Elagolix Impurity 32
Elagolix Impurity 32. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3-((R)-2-(((S)-2-amino-2-phenylethyl)amino)-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C36H33F5N4O3. Mole Weight: 664.66. Catalog: APB05823.
Elagolix Impurity 33
Elagolix Impurity 33. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R,E)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methyl-3-(2-((1-methylpyrrolidin-2-ylidene)amino)-2-phenylethyl)pyrimidine-2,4(1H,3H)-dione hydrate. Molecular Formula: C33H31F5N4O3. Mole Weight: 626.63. Catalog: APB05822.
Elagolix Impurity 34
Elagolix Impurity 34. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-tert-butyl (2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)carbamate. Molecular Formula: C33H32F5N3O5. Mole Weight: 645.63. Catalog: APB02222.
Elagolix Impurity 35
Elagolix Impurity 35. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C13H10F4N2O2. Mole Weight: 302.23. Catalog: APB05821.
Elagolix Impurity 37
Elagolix Impurity 37. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-4-((2-(5-(2-fluoro-3-hydroxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoic acid. Molecular Formula: C31H28F5N3O5. Mole Weight: 617.57. Catalog: APB02223.
Elagolix Impurity 38
Elagolix Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-4-((2-(3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoic acid. Molecular Formula: C25H25F4N3O4. Mole Weight: 507.49. Catalog: APB05819.
Elagolix Impurity 39
Elagolix Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-ethyl 4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate. Molecular Formula: C34H34F5N3O5. Mole Weight: 659.65. Catalog: APB05820.
Elagolix Impurity 4
Elagolix Impurity 4. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2375499-61-7. Molecular Formula: C32H31F4N3O5. Mole Weight: 613.61. Catalog: APB2375499617.
Elagolix Impurity 4
Elagolix Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methyl-3-(2-(2-oxopyrrolidin-1-yl)-2-phenylethyl)pyrimidine-2,4(1H,3H)-dione. CAS No. 2248628-93-3. Molecular Formula: C32H28F5N3O4. Mole Weight: 613.57. Catalog: APB2248628933.
Elagolix Impurity 40
Elagolix Impurity 40. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (S)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoic acid. Molecular Formula: C32H30F5N3O5. Mole Weight: 631.59. Catalog: APB02221.
Elagolix Impurity 41
Elagolix Impurity 41. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)(methyl)amino)butanoate. Molecular Formula: C33H31F5N3NaO5. Mole Weight: 667.60. Catalog: APB05818.
Elagolix Impurity 42 (Sodium Salt)
Elagolix Impurity 42 (Sodium Salt). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium (R)-4-((2-(3-(2-fluoro-6-(trifluoromethyl)benzyl)-5-(3-methoxyphenyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate. Molecular Formula: C32H30F4N3O5·Na. Mole Weight: 635.58. Catalog: APB05816.
Elagolix Impurity 43
Elagolix Impurity 43. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-3-(2-amino-2-phenylethyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular Formula: C21H19F4N3O2. Mole Weight: 421.39. Catalog: APB05817.
Elagolix Impurity 44 (Sodium salt)
Elagolix Impurity 44 (Sodium salt). Uses: For analytical and research use. Group: Impurity standards. Alternative Names: sodium 3-(((R)-2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate. Molecular Formula: C32H29F5N3O5·Na. Mole Weight: 653.57. Catalog: APB05815.
Elagolix Impurity 45
Elagolix Impurity 45. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2409132-65-4. Molecular Formula: C32H30F5N3O5. Mole Weight: 631.6. Catalog: APB2409132654.
Elagolix Impurity 46
Elagolix Impurity 46. Uses: For analytical and research use. Group: Impurity standards. CAS No. 748735-20-8. Molecular Formula: C9H13NO3S. Mole Weight: 215.27. Catalog: APB748735208.
Elagolix Impurity 5
Elagolix Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)(hydroxy)amino)butanoic acid. CAS No. 2409132-62-1. Molecular Formula: C32H30F5N3O6. Mole Weight: 647.59. Catalog: APB2409132621.
Elagolix Impurity 5
Elagolix Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C32H31F4N3O5. Mole Weight: 613.61. Catalog: APB07721.
Elagolix Impurity 51
Elagolix Impurity 51. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2409132-63-2. Molecular Formula: C29H24F5N3O4. Mole Weight: 573.52. Catalog: APB2409132632.
Elagolix Impurity 6
Elagolix Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-ethyl 4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate. Molecular Formula: C34H34F5N3O5. Mole Weight: 659.64. Catalog: APB05842.
Elagolix Impurity 7
Elagolix Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-3-(2-amino-2-phenylethyl)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. CAS No. 830346-50-4. Molecular Formula: C28H24F5N3O3. Mole Weight: 545.5. Catalog: APB830346504.
Elagolix Impurity 7
Elagolix Impurity 7. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C21H19F4N3O2. Mole Weight: 421.4. Catalog: APB07719.
Elagolix Impurity 8
Elagolix Impurity 8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C27H29F4N3O4. Mole Weight: 535.54. Catalog: APB07717.
Elagolix Impurity 9
Elagolix Impurity 9. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (R)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-3-(2-(hydroxyamino)-2-phenylethyl)-6-methylpyrimidine-2,4(1H,3H)-dione. CAS No. 2486454-64-0. Molecular Formula: C28H24F5N3O4. Mole Weight: 561.50. Catalog: APB2486454640.
Elagolix Impurity 9
Elagolix Impurity 9. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2316733-81-8. Molecular Formula: C40H44F5N3O7. Mole Weight: 773.8. Catalog: APB2316733818.
Elagolix sodium
Elagolix sodium is a highly effective, selective, oral-active, short-term, non-peptide gonadotropin-releasing hormone receptor (GnRH receptor) antagonist (K D = 54 pM) and NFAT inhibitor, which can be used to study pain related to endometriosis. [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NBI-56418 sodium. CAS No. 832720-36-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-14369.