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Product
Ege I One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (HindIII-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 70% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GGC↑GCC CCG↓CGG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: Enterobacter gergoviae. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1103RE. Creative Enzymes
EGF816 EGF816, also called as Nazartinib, a covalent mutant-selective EGFR inhibitor and potently inhibits the T790M resistance mutation while sparing wild-type EGFR. in vivo: demonstrated strong tumor regressions in several EGFR activating and resistant tumor m. Synonyms: EGF816; EGF-816; EGF 816; NVS-816; NVS 816; NVS816; Nazartinib; N-[7-chloro-1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamideEGF816UNII-KE7K32EME8KE7K32EME8EGF-8161508250-71-2GTPL9204SCHEMBL16767232SCHEMBL16767240EGF 816compound 47 [PMID: 27433829]. CAS No. 1508250-71-2. Molecular formula: C26H31ClN6O2. Mole weight: 495.02. BOC Sciences 7
EGF816 mesylate EGF816 mesylate is the mesylate salt of EGF816 which is a covalent mutant-selective EGFR inhibitor and potently inhibits the T790M. Synonyms: N-[7-chloro-1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamide; methanesulfonic acid. CAS No. 1508250-72-3. Molecular formula: C27H35ClN6O5S. Mole weight: 591.12. BOC Sciences 7
EGF-A Peptide EGF-A Peptide. Synonyms: Gly-Thr-Asn-Glu-Cys-Leu-Asp-Asn-Asn-Gly-Gly-Cys-Ser-His-Val-Cys-Asn-Asp-Leu-Lys-Ile-Gly-Tyr-Glu-Cys-Leu-Cys-Pro-Asp-Gly-Phe-Gln-Leu-Val-Ala-Gln-Arg-Arg-Cys-Glu-Asp-Ile-NH2 (Disulfide bond Cys5/Cys16, Cys12/Cys25, Cys27/Cys39). Molecular formula: C188H292N58O65S6. Mole weight: 4597.00. BOC Sciences 10
EGF-R (1138-1147) A peptide fragment of EGF-R. Epidermal growth factor receptor (EGFR) is a prototypic cell-surface receptor belonging to the ErbB/HER onocogene family. Targeting of EGFR with specific blocking antibodies or inhibitors have been developing for treatment for EGFR-associated tumors. Synonyms: Epidermal growth factor receptor (1138-1147). BOC Sciences 10
EGFR/CSC-IN-1 EGFR/CSC-IN-1 is a potential dual inhibitor of EGFR and cancer stem cell (CSC) with an IC50 of 10.52 nM for EGFR. It is used to treat triple negative breast cancer. Synonyms: 2-(4-(3-(2-chloro-10H-phenothiazin-10-yl)propyl)piperazin-1-yl)ethyl 4-(((5-(4-((3-chloro-4-((3-fluorobenzyl)oxy)phenyl)amino)quinazolin-6-yl)furan-2-yl)methyl)(2-(methylsulfonyl)ethyl)amino)-4-oxobutanoate. Molecular formula: C54H54Cl2FN7O7S2. Mole weight: 1067.08. BOC Sciences 7
EGF Receptor (985-996) (human) EGF Receptor (985-996) (human) exists on the cell surface and is activated by the binding of its specific ligands. EGFR belongs to the tyrosine kinase receptor (RTK) ErbB family. Synonyms: L-Glutamine, L-α-aspartyl-L-valyl-L-valyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-tyrosyl-L-leucyl-L-isoleucyl-L-prolyl-; L-Glutamine, N2-[1-[N-[N-[N-[N-[N-[N-[N-[N-(N-L-α-aspartyl-L-valyl)-L-valyl]-L-α-aspartyl]-L-alanyl]-L-α-aspartyl]-L-α-glutamyl]-L-tyrosyl]-L-leucyl]-L-isoleucyl]-L-prolyl]-; L-α-Aspartyl-L-valyl-L-valyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-tyrosyl-L-leucyl-L-isoleucyl-L-prolyl-L-glutamine; H-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH; Epidermal Growth Factor Receptor Peptide. Grade: ≥95%. CAS No. 96249-43-3. Molecular formula: C61H93N13O23. Mole weight: 1376.46. BOC Sciences
EGF Receptor Antibody [K22M8] EGF Receptor,EGFR,Epidermal Growth Factor Receptor. Group: Antibodies. Alternative Names: EGF Receptor,EGFR,Epidermal Growth Factor Receptor. Pack Sizes: 20ul. Product ID: F0053. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. Selleck Chemicals
United States; Europe
EGF Receptor Substrate 2 Phospho-Tyr5 EGF Receptor Substrate 2 Phospho-Tyr5 is a bioactive peptide derived from the autophosphorylation site (Tyr992) of the epidermal growth factor receptor (EGFR). Synonyms: H-Asp-Ala-Asp-Glu-pTyr-Leu-Ile-Pro-Gln-Gln-Gly-OH. Grade: ≥95%. Molecular formula: C54H82N13O24. Mole weight: 1328.28. BOC Sciences 10
EGFR/ErbB2 Inhibitor EGFR/ErbB2 inhibitor is a cell-permeable 4-anilino quinazoline compound, which is a potent and reversible inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively). It inhibits the proliferation of cancer cells overexpressing either c-ErbB2 or EGFR (IC50s = 2.3-2.5 μM). Synonyms: 4557W; 4-(4-Benzyloxyanilino)-6,7-dimethoxyquinazoline; EGFR/ErbB-2 Inhibitor. Grade: ≥95%. CAS No. 179248-61-4. Molecular formula: C23H21N3O3. Mole weight: 387.4. BOC Sciences 7
EGFR-IN-1 EGFR-IN-1 is an orally active and irreversible mutant selective EGFR inhibitor of L858R/T790M that effectively inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. It shows strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. It has antitumor activity. Synonyms: N-{3-[2-({4-[2-(Dimethylamino)ethoxy]-2-methoxyphenyl}amino)-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl]phenyl}acrylamide; 2-Propenamide, N-[3-[2-[[4-[2-(dimethylamino)ethoxy]-2-methoxyphenyl]amino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl]phenyl]-. Grade: ≥95%. CAS No. 1625677-63-5. Molecular formula: C28H30N6O4. Mole weight: 514.58. BOC Sciences 7
EGFR-IN-11 EGFR-IN-11 is a fourth-generation EGFR-tyrosine kinase inhibitor (EGFR-TKI) with an IC50 of 18 nM against the triple mutant EGFRL858R/T790M/C797S. It significantly inhibits EGFR phosphorylation, induces apoptosis and arrests cell cycle at G0/G1. Synonyms: 9H-Purine-2,8-diamine, 9-[(3R)-1-(cyclopropylsulfonyl)-3-pyrrolidinyl]-N2-[4-(4-methyl-1-piperazinyl)phenyl]-N8-phenyl-; 9-[(3R)-1-(Cyclopropylsulfonyl)-3-pyrrolidinyl]-N2-[4-(4-methyl-1-piperazinyl)phenyl]-N8-phenyl-9H-purine-2,8-diamine. Grade: ≥95%. CAS No. 2463200-44-2. Molecular formula: C29H35N9O2S. Mole weight: 573.71. BOC Sciences 7
EGFR-IN-12 EGFR-IN-12 is a 4,6-disubstituted pyrimidine and is a potent, ATP-competitive, irreversible and highly selective EGFR inhibitor with an IC50of 21 nM. EGFR-IN-12 also inhibits mutant EGFRL858R and EGFRL861Q with IC50s of 63 nM and 4 nM, respectively. EGFR-IN-12 displays strong selectivity for EGFR over HER4 (IC50 = 7640 nM) and a panel of 55 other kinases. EGFR-IN-12 induces cells apoptosis and has antitumor activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 879127-07-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17499. MedChemExpress MCE
EGFR-IN-15 EGFR-IN-15, an EGFR inhibitor with an IC50 of 4 nM, can be used in the study of oncological disease. Synonyms: 1H,10H-4,8-Metheno-17H-pyrazolo[3',4':2,3][1,5,10,12]oxatriazacycloheptadecino[12,11-a]benzimidazol-9-one, 14-bromo-18,19,20,21-tetrahydro-1,6,18-trimethyl-, (18R)-. CAS No. 2573869-16-4. Molecular formula: C24H25BrN6O2. Mole weight: 509.40. BOC Sciences 7
EGFR-IN-16 EGFR-IN-16 is a potent inhibitor of EGFR with pIC50 of 4.85 and 4.74 for EGFR and HER-2, respectively. Synonyms: Benzenepropanenitrile, α-[(3,4-dihydroxyphenyl)methylene]-β-oxo-, (αE)-; (E)-2-Benzoyl-3-(3,4-dihydroxyphenyl)acrylonitrile; (2E)-2-benzoyl-3-(3,4-dihydroxyphenyl)prop-2-enenitrile; (2E)-2-Benzoyl-3-(3,4-dihydroxyphenyl)acrylonitrile. Grade: ≥95%. CAS No. 133550-22-8. Molecular formula: C16H11NO3. Mole weight: 265.26. BOC Sciences 7
EGFR-IN-17 EGFR-IN-17 is a potent and selective epidermal growth factor receptor inhibitor (IC50 = 0.0002 μM) that overcomes C797S-mediated resistance. Synonyms: (2-((5-chloro-2-((2-methoxy-5-(1-methyl-1H-pyrazol-4-yl)-4-morpholinophenyl)amino)pyrimidin-4-yl)amino)phenyl)dimethylphosphine oxide. Molecular formula: C27H31ClN7O3P. Mole weight: 568.01. BOC Sciences 7
EGFR-IN-18 EGFR-IN-18 effectively inhibits enzymatic activity in L858R/T790M/C797S mutant EGFR, but has a significantly lower activity for wild-type EGFR. Synonyms: N-[3-[5-(2-acetamidopyridin-4-yl)-2-methylsulfanyl-1H-imidazol-4-yl]phenyl]-2-[(3-oxo-1H-isoindol-2-yl)methyl]benzamide; N-(3-{5-[2-(acetylamino)pyridin-4-yl]-2-(methylsulfanyl)-1H-imidazol-4-yl}phenyl)-2-[(1-oxo-1,3-dihydro-2H-isoindol-2-yl)methyl]benzamide; TQA. Molecular formula: C33H28N6O3S. Mole weight: 588.68. BOC Sciences 7
EGFR-IN-1 hydrochloride EGFR-IN-1 hydrochloride is an orally active and irreversible mutant selective EGFR inhibitor of L858R/T790M that effectively inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. It shows strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. It has antitumor activity. Synonyms: N-{3-[2-({4-[2-(Dimethylamino)ethoxy]-2-methoxyphenyl}amino)-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl]phenyl}acrylamide hydrochloride (1:1); 2-Propenamide, N-[3-[2-[[4-[2-(dimethylamino)ethoxy]-2-methoxyphenyl]amino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl]phenyl]-, hydrochloride (1:1). Grade: ≥95%. CAS No. 2227455-78-7. Molecular formula: C28H31ClN6O4. Mole weight: 551.04. BOC Sciences 7
EGFR-IN-1 TFA EGFR-IN-1 TFA is an orally active and irreversible mutant selective EGFR inhibitor of L858R/T790M that effectively inhibits Gefitinib-resistant EGFR L858R, T790M with 100-fold selectivity over wild-type EGFR. It shows strong antiproliferative activity against the H1975 cells and the first line mutant HCC827 cells. It has antitumor activity. Synonyms: N-{3-[2-({4-[2-(Dimethylamino)ethoxy]-2-methoxyphenyl}amino)-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl]phenyl}acrylamide trifluoroacetate (1:1); Acetic acid, 2,2,2-trifluoro-, compd. with N-[3-[2-[[4-[2-(dimethylamino)ethoxy]-2-methoxyphenyl]amino]-5-methyl-7-oxopyrido[2,3-d]pyrimidin-8(7H)-yl]phenyl]-2-propenamide (1:1). Grade: ≥99%. Molecular formula: C30H31F3N6O6. Mole weight: 628.60. BOC Sciences 7
EGFR-IN-2 EGFR-IN-2 is a a noncovalent, irreversible, mutant-selective second generation EGFR inhibitor. It showed excellent cellular activity against both the single and double mutants of EGFR, demonstrating target engagement in vivo and ADME-PK properties that are suitable for further evaluation. CAS No. 1643497-70-4. Molecular formula: C26H33N9O3S. Mole weight: 551.66. BOC Sciences 7
EGFR-IN-5 EGFR-IN-5 is an inhibitor of EGFR with IC50s of 10.4, 1.1, 34 and 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M and EGFRL858R/T790M/C797S, respectively. Synonyms: mutant EGFR inhibitor B30; (1-(6-((5-(4-(Dimethylamino)piperidin-1-yl)pyridin-2-yl)amino)-2-((4-fluorophenyl)amino)pyrido[3,4-d]pyrimidin-4-yl)piperidin-4-yl)methanol; 4-Piperidinemethanol, 1-[6-[[5-[4-(dimethylamino)-1-piperidinyl]-2-pyridinyl]amino]-2-[(4-fluorophenyl)amino]pyrido[3,4-d]pyrimidin-4-yl]-. Grade: ≥95%. CAS No. 2225887-26-1. Molecular formula: C31H38FN9O. Mole weight: 571.69. BOC Sciences 7
EGFR-IN-5 EGFR-IN-5 is a EGFR inhibitor with IC50s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFRL858R, EGFRL858R/T790M, and EGFRL858R/T790M/C797S, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 2225887-26-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111415. MedChemExpress MCE
EGFR-IN-7 EGFR-IN-7 is a potent, selective and orally active EGFR kinase inhibitor. EGFR-IN-7 has inhibitory effect for for EGFR (WT) and EGFR (mutant C797S/T790M/L858R) with IC50 values of 7.92 nM and 0.218 nM, respectively. EGFR-IN-7 can be used for the research of various cancers[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2267329-76-8. Pack Sizes: 5 mg; 10 mg; 50 mg. Product ID: HY-128862. MedChemExpress MCE
EGFR-IN-7 EGFR-IN-7 Inhibitor. Uses: Scientific use. Product Category: T11161. CAS No. 2267329-76-8. TARGETMOL CHEMICALS
EGFR-IN-7 EGFR-IN-7 is a selective and potent EGFR kinase inhibitor. TQB3804 displays potent enzymatic activities for EGFRd746-750/T790M/C797S, EGFRL858R/T790M/C797S, EGFRd746-750/T790M, and EGFRL858R/T790M with IC50 of 0.46, 0.13, 0.26, and 0.19 nM, respectively. Synonyms: TQB3804. CAS No. 2267329-76-8. Molecular formula: C32H41BrN9O2P. Mole weight: 694.60. BOC Sciences 7
EGFR-IN-70 EGFR-IN-70 (compound 18j) is a potent EGFR inhibitor with IC50 values of 23.6 and 307.5 nM for EGFRLR/TM/CS and EGFRWT, respectively. EGFR-IN-70 has anti-proliferative activity and suppresses phosphorylation of the EGFR. EGFR-IN-70 can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2926716-96-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150611. MedChemExpress MCE
EGFR-IN-8 EGFR-IN-8, a dual inhibitor of EGFR and c-Met, may be a promising candidate for further development to target EGFR TKI-resistant NSCLC. Synonyms: N-(3-Chloro-4-(5-(3-(3-(4-(cyclopropanecarboxamido)-3-(trifluoromethyl)phenyl)ureido)phenyl)-1,2,4-oxadiazol-3-yl)phenyl)nicotinamide; N-(3-chloro-4-{5-[3-({[4-cyclopropaneamido-3-(trifluoromethyl)phenyl]carbamoyl}amino)phenyl]-1,2,4-oxadiazol-3-yl}phenyl)pyridine-3-carboxamide; 3-Pyridinecarboxamide, N-[3-chloro-4-[5-[3-[[[[4-[(cyclopropylcarbonyl)amino]-3-(trifluoromethyl)phenyl]amino]carbonyl]amino]phenyl]-1,2,4-oxadiazol-3-yl]phenyl]-. Grade: ≥98%. CAS No. 2407957-87-1. Molecular formula: C32H23ClF3N7O4. Mole weight: 662.02. BOC Sciences 7
EGFR-IN-86 EGFR-IN-86 (compound 4i) is an EGFR inhibitor (IC50: 1.5 nM) with high activity against glioblastoma. EGFR-IN-86 induces apoptosis and arrests the U87 cell cycle in the G2/M phase[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3055550-22-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-149530. MedChemExpress MCE
EGFR-IN-9 EGFR-IN-9 is a potent inhibitor of EGFR kinase with IC50s of 7 and 28 nM for the wild type EGFR kinase and double mutant EGFR kinase (L858R/T790M). It has antitumor activity. Synonyms: (S)-N-(3-(4-(2-hydroxy-1-phenylethylamino)-6-phenylfuro[2,3-d]pyrimidin-5-yl)phenyl)acrylamide; 2-Propenamide, N-[3-[4-[[(1S)-2-hydroxy-1-phenylethyl]amino]-6-phenylfuro[2,3-d]pyrimidin-5-yl]phenyl]-. Grade: ≥95%. CAS No. 1226549-39-8. Molecular formula: C29H24N4O3. Mole weight: 476.53. BOC Sciences 7
EGFR-IN-95 EGFR-IN-95 (compound 5j) is an 2,4-diaminonicotinamide derivative. EGFR-IN-95 has potent inhibitory activity against EGFR del19/T790M/C797S and L858R/T790M/C797S[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3027135-04-9. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-163094. MedChemExpress MCE
EGFR-IN-99 EGFR-IN-99 (compound 1a) is a potent EGFR and HER2 Exon 20 insertion mutant inhibitor. EGFR-IN-99 has excellent antiproliferative activity against DFCI127 cells, with an EC50 of 11.5 nM. EGFR-IN-99 can be used for the research of non-small cell lung cancer (NSCLC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2068806-31-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-123766. MedChemExpress MCE
EGFR Inhibitor A cell-permeable and highly selective EGFR tyrosine kinase inhibitor with IC50 value in the nanomolar range. Inhibition of EGFR induces apoptosis of tumor cells by ownregulating antiapoptotic proteins such as survivin and upregulating proapoptotic proteins such as Bim. Uses: Antitumor agent. Synonyms: EGFR inhibitor; EGFR-inhibitor; EGFRinhibitor; Cyclopropanecarboxylic acid-(3-(6-(3-trifluoromethyl-phenylamino)-pyrimidin-4-ylamino)-phenyl)-amide; N-(3-((6-((3-(Trifluoromethyl)phenyl)amino)pyrimidin-4-yl)amino)phenyl)cyclopropanecarboxamide; K00598a. Grade: 99%. CAS No. 879127-07-8. Molecular formula: C21H18F3N5O. Mole weight: 413.4. BOC Sciences 7
EGFR kinase inhibitor 3 EGFR kinase inhibitor 3 (compound 2) is a bivalent ATP-allosteric EGFR kinase inhibitor with IC50s of <10 nM, 1.5 nM, 0.059 nM, 0.064 nM for WT EGFR, EGFR-activating mutations L858R, L858R/T790M and L858R/T790M/C797S, respectively. EGFR kinase inhibitor 3 is a C-linked inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2922402-03-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-162299. MedChemExpress MCE
EGFR mutant-IN-1 EGFR mutant-IN-1 is a potent and selective EGFRL858R/T790M/C797S mutant inhibitor (IC50 = 27.5 nM), and a significantly less potent for EGFRWT (IC50 >1.0 μM). Synonyms: 6-(2-Chloro-3-fluorophenyl)-5-methyl-2-{[3-methyl-4-(4-methyl-1-piperazinyl)phenyl]amino}-8-[(3R)-1-propionyl-3-piperidinyl]pyrido[2,3-d]pyrimidin-7(8H)-one; Pyrido[2,3-d]pyrimidin-7(8H)-one, 6-(2-chloro-3-fluorophenyl)-5-methyl-2-[[3-methyl-4-(4-methyl-1-piperazinyl)phenyl]amino]-8-[(3R)-1-(1-oxopropyl)-3-piperidinyl]-. Molecular formula: C34H39ClFN7O2. Mole weight: 632.17. BOC Sciences 7
EGFRvIII peptide (PEPvIII) EGFRvIII peptide (PEPvIII), a tumor-specific mutation and a target for anti-tumor immunotherapy, is widely expressed in glioblastoma multiforme (GBM) and other tumors, and its expression enhances tumorigenicity. Synonyms: H-Leu-Glu-Glu-Lys-Lys-Gly-Asn-Tyr-Val-Val-Thr-Asp-His-Cys-OH; L-leucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-lysyl-L-lysyl-glycyl-L-asparagyl-L-tyrosyl-L-valyl-L-valyl-L-threonyl-L-alpha-aspartyl-L-histidyl-L-cysteine. Grade: ≥95%. CAS No. 129112-17-0. Molecular formula: C70H111N19O24S. Mole weight: 1634.81. BOC Sciences 10
Eggcrate Charcoal Firm Foam With its classic shape, our high-quality eggcrate charcoal firm foam offers extra cushioning and airflow while still being one of the most economical choices on the market today. It replicates the effects of standard charcoal firm sheet foam more economically, due to our cutting process and the shape adds extra benefits. Alfa Chemistry Materials 6
Eggcrate Charcoal Regular Foam With its familiar, classic design, charcoal regular eggcrate foam replicates the effects of charcoal regular sheet foam more economically, due to our cutting process. Its non-soiling surface makes it appropriate for use in any area charcoal regular foam can be applied. Alfa Chemistry Materials 6
Eggcrate-Charcoal Regular Foam Top/Lid Eggcrate toppers and lids are a perfect complement to your custom packaging or casing when placed over your Pick and Pull Grid core design. Alfa Chemistry Materials 6
Eggcrate Pink Anti-Static Foam Top/Lid Eggcrate toppers and lids are a perfect complement to your custom packaging or casing when placed over your Pick and Pull Grid core design. Alfa Chemistry Materials 6
Egg Laying Hormone, aplysia Egg Laying Hormone, aplysia is a neuropeptide containing 36 amino acids synthesized by the neurons of the bag cell, which can stimulate oviposition and ovulation in Aplysia by electrical discharge triggering of neurons. Egg Laying Hormone, aplysia induces a voltage-dependent slow inward current carried by Na+ in an identified motoneuron. Synonyms: Egg-laying hormone (Aplysia brasiliana bag cell); Ile-Ser-Ile-Asn-Gln-Asp-Leu-Lys-Ala-Ile-Thr-Asp-Met-Leu-Leu-Thr-Glu-Gln-Ile-Arg-Glu-Arg-Gln-Arg-Tyr-Leu-Ala-Asp-Leu-Arg-Gln-Arg-Leu-Leu-Glu-Lys-NH2; ELH, aplysia; L-Lysinamide, L-isoleucyl-L-seryl-L-isoleucyl-L-asparaginyl-L-glutaminyl-L-a-aspartyl-L-leucyl-L-lysyl-L-alanyl-L-isoleucyl-L-threonyl-L-a-aspartyl-L-methionyl-L-leucyl-L-leucyl-L-threonyl-L-a-glutamyl-L-glutaminyl-L-isoleucyl-L-arginyl-L-a-glutamyl-L-arginyl-L-glutaminyl-L-arginyl-L-tyrosyl-L-leucyl-L-alanyl-L-a-aspartyl-L-leucyl-L-arginyl-L-glutaminyl-L-arginyl-L-leucyl-L-leucyl-L-a-glutamyl-. Grade: ≥95%. CAS No. 117680-39-4. Molecular formula: C190H329N59O57S. Mole weight: 4384.20. BOC Sciences 10
Eggmanone Eggmanone is a potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50 = 72 nM) displaying >40-fold selectivity over PDE3, PDE10, and PDE11. Eggmanone acts via blocking hedgehog signaling through PDE antagonism, downstream of smoothened signaling. Synonyms: 5,6,7,8-Tetrahydro-3-(2-methyl-2-propen-1-yl)-2-[[2-oxo-2-(2-thienyl)ethyl]thio]-[1]benzothieno[2,3-d]pyrimidin-4(3H)-one. Grade: ≥98% by HPLC. CAS No. 505068-32-6. Molecular formula: C20H20N2O2S3. Mole weight: 416.58. BOC Sciences 7
Egg oil Egg oil is a natural oil, which consists primarily of cholesterol, lecithin and glycerides of the fatty acids. Egg oil exhibits activity in regulating the gut microbial dysbiosis, alleviating obesity, insulin resistance and inflammation[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 8001-17-0. Pack Sizes: 25 mg; 50 mg. Product ID: HY-N12670. MedChemExpress MCE
Egg PC (60%) Egg PC (60%). Group: Others. L-α-phosphatidylcholine (Egg, Chicken-60%) (Total Egg Phosphatide Extract); Egg PC (60%). Cat No: PHOZ-245. Creative Enzymes
Egg phosphatidylglycerol Egg phosphatidylglycerol. Synonyms: EPG. CAS No. 383907-64-0. Product ID: PE-0569. Molecular formula: C40H76NaO10P. Mole weight: 782.284. Category: Emulsifier. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0569; Egg phosphatidylglycerol; Emulsifier; C40H76NaO10P; 383907-64-0. UNII: NA. Chemical Name: 1, 2-Diacyl-sn-Glycero-3-Phospho-[1-rac-glycerol]. Grade: Pharmceutical Excipients. Administration route: Intravenous injection. Dosage Form: Intravenous injection. Stability and Storage Conditions: Soluble in chloroform, slightly soluble in ethanol, insoluble in water. This product should be dark, sealed, frozen transportation and storage, avoid storage with strong oxidizing substances. Proper use and preservation of the condition of quality can be guaranteed for three years. Phospholipids can be hydrolyzed in strong acid and base environments, so contact with strong acid or base media should be avoided except for strong oxidizing substances. Commonly used amount and the maximum amount: The maximum dosage of intravenous injection is 0.36mg. CD Formulation
Egg Phospholipids Egg Phospholipids. Synonyms: E322; egg lecithin; LSC 5050; LSC 6040; mixed soybean phosphatides; ovolecithin; Phosal 53 MCT; Phospholipon 100 H; ProKote LSC; soybean lecithin; soybean phospholipids; Sternpur; vegetable lecithin. CAS No. 93685-90-6. Product ID: PE-0429. Category: Dispersants; Emollient; emulsifying agent. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Egg Phospholipids; Dispersion Excipients; Dispersants; Emollient; emulsifying agent; 93685-90-6; 93685-90-6. UNII: 1Z74184RGV. Chemical Name: Egg yolk lecithin. Grade: Pharmceutical Excipients. Administration route: Intravenous, oral. Dosage Form: Injection, Emulsion, Powder lyophilized, for soultion, Tablet. CD Formulation
Egg yolk lecithin Lecithins vary greatly in their physical form, from viscous semiliquids to powders, depending upon the free fatty acid content. They may also vary in color from brown to light yellow, depending upon whether they are bleached or unbleached or on the degree of purity. When they are exposed to air, rapid oxidation occurs, also resulting in a dark yellow or brown color. Lecithins have practically no odor. Those derived from vegetable sources have a bland or nutlike taste, similar to that of soybean oil. Synonyms: E322; egg lecithin; LSC 5050; LSC 6040; mixed soybean phosphatides; ovolecithin; Phosal 53 MCT; Phospholipon 100 H; ProKote LSC; soybean lecithin; soybean phospholipids; Sternpur; vegetable lecithin. CAS No. 93685-90-6. Product ID: PE-0112. Category: Emollient; Emulsifying Agents; Solubilizing Agents. Product Keywords: Humectants Excipients; Stabilizers; Emulsifier & Suspending Agents; ; PE-0112; Egg yolk lecithin; Emollient; Emulsifying Agents; Solubilizing Agents; ; 93685-90-6. UNII: 1Z74184RGV. Chemical Name: Egg Phospholipids. Grade: Pharmceutical Excipients. Administration route: Intravenous, oral. Dosage Form: Injection, Emulsion, Powder lyophilized, for soultion, Tablet. Stability and Storage Conditions: Lecithins decompose at extreme pH. They are also hygroscopic and subject to microbial degradation. When heated, lecithins oxidize, darken, and decompose. Temperatures of 160-180°C will cause degradatio… CD Formulation
Eghoxylated Bisphenol-A Diacrylate Eghoxylated Bisphenol-A Diacrylate. Alfa Chemistry Materials 2
EGIS-8332 EGIS-8332 potently decreased AMPA and quisqualate induced LDH release (IC50 = 5.2 ± 0.4 and 7.4 ± 1.3 μM, respectively) from the cells. The inhibition of the AMPA/kainate ion channels by EGIS-8332 is non-competitive, not use dependent, and depends neither on the closed/open state of the channel, nor the membrane potential. Synonyms: 7-acetyl-5-(4-aminophenyl)-8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-8-carbonitrile; EGIS-8332; EGIS 8332; EGIS8332. Grade: >98%. CAS No. 220725-87-1. Molecular formula: C20H18N4O3. Mole weight: 362.389. BOC Sciences 7
Eglin c(42-45)-methyl ester. hcl Eglin c(42-45)-methyl ester. hcl. Alternative Names: PRO-VAL-THR-LEU-OME;H-PRO-VAL-THR-LEU-OME HCL;EGLIN C (42-45)-METHYL ESTER;EGLIN C (42-45)-METHYL ESTER. HCL. CAS No. 133463-25-9. Product ID: ACM133463259. Molecular formula: C21H38N4O6.HCl. Mole weight: 442.55. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry. 5
Eglin c(60-63)-methyl ester Eglin c(60-63)-methyl ester. Alternative Names: THR-ASN-VAL-VAL-OME;EGLIN C (60-63)-METHYL ESTER;EGLIN C (60-63)-METHYL ESTER ACETATE SALT;H-THR-ASN-VAL-VAL-OME ACETATE SALT;H-THR-ASN-VAL-VAL-OME ACOH;eglin C fragment 60-63 methyl ester;H-Thr-Asn-Val-Val-OMe. CAS No. 131696-94-1. Purity: 96%. Product ID: ACM131696941. Molecular formula: C19H35N5O7. Mole weight: 505.56. IUPAC Name: methyl (2S)-2-[[(2S)-2-[[(2S)-4-amino-2-[[(2S,3R)-2-amino-3-hydroxybutanoyl]amino]-4-oxobutanoyl]amino]-3-methylbutanoyl]amino]-3-methylbutanoate. Alfa Chemistry - ISO 9001:32057 Certified. Alfa Chemistry. 5
EGLU EGLU ((2S)-α-Ethylglutamic acid; (2S)-α-EGLU) is a potent and competitive mGluR-2 receptor antagonist. EGLU interacts with (lS,3S)-ACPD-sensitive site with a Kd value of 66 μM. EGLU is an antidepressant agent[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (2S)-α-Ethylglutamic acid; (2S)-α-EGLU. CAS No. 170984-72-2. Pack Sizes: 1 mg; 5 mg. Product ID: HY-101332. MedChemExpress MCE
EGLU EGLU is a group II mGluR antagonist and also a selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neonatal rat spinal cord. Synonyms: (2S)-α-Ethylglutamic acid; (2S)-2-amino-2-ethylpentanedioic acid. Grade: ≥95% by HPLC. CAS No. 170984-72-2. Molecular formula: C7H13NO4. Mole weight: 175.18. BOC Sciences 7
Eglumegad Eglumegad (LY354740) is a highly potent and selective group II (mGlu2/3) receptor agonist with IC50s of 5 nM and 24 nM on transfected human mGlu2 and mGlu3 receptors, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY354740; Eglumetad. CAS No. 176199-48-7. Pack Sizes: 10 mM * 1 mL in Water; 5 mg; 10 mg; 25 mg. Product ID: HY-18941. MedChemExpress MCE
EGNHS EGNHS is an alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EGS crosslinker. CAS No. 70539-42-3. Pack Sizes: 50 mg; 100 mg; 250 mg; 500 mg; 1 g; 5 g; 10 g; 25 g. Product ID: HY-130458. MedChemExpress MCE
EGR-1-IN-1 EGR-1-IN-1 is a EGR-1 inhibitor with an IC50 of 1.86 μM. EGR-1-IN-1 binds to the zinc finger DNA-binding domain of EGR-1 and promotes the dissociation of the EGR-1-DNA complex. EGR-1-IN-1 reduces the mRNA expression levels of EGR-1-regulated inflammatory genes induced by TNFα. EGR-1-IN-1 alleviates atopic dermatitis-like lesions in the ear skin of mice. EGR-1-IN-1 serves as a lead compound for the development of targeted compounds for inflammatory skin diseases. EGR-1-IN-1 can be used in studies related to atopic dermatitis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3077196-25-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163731. MedChemExpress MCE
EGT1442 EGT1442 is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively. It significantly prolonged the median survival of SHRSP rats. It attenuates blood glucose and HbA(1c) levels and prolongs the survival of stroke-prone rats in db/db mice. It showed favorable properties both in vitro and in vivo and could be beneficial to the management of type 2 diabetic patients. It was developed by Theracos and in clinic phase 1 trials. Uses: Egt1442 showed favorable properties and could be beneficial to the management of type 2 diabetic patients. Synonyms: THR1442; THR-1442; THR 1442; EGT1442; EGT-1442; EGT 1442; Bexagliflozin; (1S)-1,5-Anhydro-1-C-[4-chloro-3-[[4-[2-(cyclopropyloxy)ethoxy]phenyl]methyl]phenyl]-D-glucitol; Bexagliflozin; THR1442; EGT0001442; EGT-1442; THR-1442; EGT-0001442; (2S,4R,6R)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol; (3R,4R,5S,6R)-2-(4-chloro-3-(4-(2-cyclopropoxyethoxy)benzyl)phenyl)-6-(hydroxymethyl)tetrahydro-2H-pyran-3,4,5-triol. Grade: >98%. CAS No. 1118567-05-7. Molecular formula: C24H29ClO7. Mole weight: 464.94. BOC Sciences 7
EGTA 25g Pack Size. Group: Biochemicals, Ligands. Formula: C14H24N2O10. CAS No. 67-42-5. Prepack ID 29346817-25g. Molecular Weight 380.35. See USA prepack pricing. Molekula Americas
EGTA EGTA is a cell-impermeant specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca2+ over Mg2+ (Mg2+ Kd 1-10 mM). EGTA significantly inhibits the substrate adherence capacity of inflammatory macrophages[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 67-42-5. Pack Sizes: 500 mg; 1 g; 5 g; 10 g. Product ID: HY-D0861. MedChemExpress MCE
EGTA Chelating agent for the determination of calcium. Group: Biochemicals. Alternative Names: Ethyleneglycol-bis-(2 aminoethylether)-N,N.N,N-tetraacetic acid; Glycol ether diamine tetraacetic acid; Egtazic acid. Grades: Molecular Biology Grade. CAS No. 67-42-5. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C14H24N2O10, Molecular Weight: 380.35. US Biological Life Sciences. USBiological 10
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EGTA-AM EGTA-AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-AM is also a Ca2+ chelator with slow chelating dynamics. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EGTA Acetoxymethyl ester. CAS No. 99590-86-0. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-D0973. MedChemExpress MCE
EGTA tetrasodium EGTA tetrasodium. Group: Biochemicals. Alternative Names: Ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid tetrasodium salt. Grades: Highly Purified. CAS No. 13368-13-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C14H20N2O10·4Na. US Biological Life Sciences. USBiological 10
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EGTA tetrasodium EGTA tetrasodium is a cell-impermeant specific calcium ion chelator. EGTA tetrasodium has an apparent calcium dissociation constant (Kd) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca2+ over Mg2+ (Mg2+ Kd 1-10 mM). EGTA tetrasodium significantly inhibits the substrate adherence capacity of inflammatory macrophages[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 13368-13-3. Pack Sizes: 10 mM * 1 mL in Water; 500 mg; 1 g. Product ID: HY-D0861A. MedChemExpress MCE
EH-IDTBR EH-IDTBR. Molecular formula: C72H88N6O2S8. Mole weight: 1326g/mol. IUPAC Name: (5Z)-3-ethyl-2-sulfanylidene-5-[[4-[9,9,18,18-tetrakis(2-ethylhexyl)-15-[7-[(Z)-(3-ethyl-4-oxo-2-sulfanylidene-1,3-thiazolidin-5-ylidene)methyl]-2,1,3-benzothiadiazol-4-yl]-5,14-dithiapentacyclo[10.6.0.03,10.04,8.013,17]octadeca-1(12),2,4(8),6,10,13(17),15-heptaen-6-yl]-2,1,3-benzothiadiazol-7-yl]methylidene]-1,3-thiazolidin-4-one. SMILES: CCCCC(CC)CC1(C2=CC3=C(C=C2C4=C1C=C(S4)C5=CC=C(C6=NSN=C56)C=C7C(=O)N(C(=S)S7)CC)C(C8=C3SC(=C8)C9=CC=C(C1=NSN=C91)C=C1C(=O)N(C(=S)S1)CC)(CC(CC)CCCC)CC(CC)CCCC)CC(CC)CCCC. InChI: InChI=1S/C72H88N6O2S8/c1-11-21-25-43(15-5)39-71(40-44(16-6)26-22-12-2)53-35-52-54(36-51(53)65-55(71)37-57(83-65)49-31-29-47(61-63(49)75-87-73-61)33-59-67(79)77(19-9)69(81)85-59)72(41-45(17-7)27-23-13-3,42-46(18-8)28-24-14-4)56-38-58(84-66(52)56)50-32-30-48(62-64(50)76-88-74-62)34-60-68(80)78(20-10)70(82)86-60/h29-38,43-46H,11-28,39-42H2,1-10H3/b59-33-,60-34-. Alfa Chemistry Materials 5
EHMT2-IN-1 EHMT2-IN-1 is a potent inhibitor of EHMT, with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2. It is used for the study of blood disorder or cancer. Synonyms: N2-(4-Methoxy-3-{4-[(methylamino)methyl]-1H-pyrazol-1-yl}phenyl)-N4,6-dimethyl-2,4-pyrimidinediamine; 2,4-Pyrimidinediamine, N2-[4-methoxy-3-[4-[(methylamino)methyl]-1H-pyrazol-1-yl]phenyl]-N4,6-dimethyl-. Grade: ≥97%. CAS No. 2230849-55-3. Molecular formula: C18H23N7O. Mole weight: 353.42. BOC Sciences 7
EHMT2-IN-1 EHMT2-IN-1 is a potent EHMT inhibitor, with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2. Used in the research of blood disorder or cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230849-55-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111778. MedChemExpress MCE
EHMT2-IN-2 EHMT2-IN-2 is a potent EHMT inhibitor, with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2. Used in the research of blood disease or cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230850-47-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-111904. MedChemExpress MCE
EHMT2-IN-2 EHMT2-IN-2 is a potent inhibitor of EHMT, with IC50s of all <100 nM for EHMT1 peptide, EHMT2 peptide and cellular EHMT2. It is used for the study of blood disorder or cancer. Synonyms: EHMT2 inhibitor 2; 2,4-Pyrimidinediamine, N2-[4-methoxy-3-(3-methyl-1H-pyrrolo[2,3-c]pyridin-2-yl)phenyl]-N4,6-dimethyl-; N2-[4-Methoxy-3-(3-methyl-1H-pyrrolo[2,3-c]pyridin-2-yl)phenyl]-N4,6-dimethyl-2,4-pyrimidinediamine. Grade: ≥95%. CAS No. 2230850-47-0. Molecular formula: C21H22N6O. Mole weight: 374.44. BOC Sciences 7
EHNA hydrochloride EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2)(IC50=4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)(IC50:0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 58337-38-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103160A. MedChemExpress MCE
EHNA hydrochloride EHNA hydrochloride is a selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 μM) and also an inhibitor of adenosine deaminase. EHNA inhibits spontaneous differentiation of human ESCs in feeder-free conditions and directed neuronal differentiation. Uses: Antiviral agents. Synonyms: (2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol hydrochloride. Grade: >98%. CAS No. 58337-38-5. Molecular formula: C14H23N5O.HCl. Mole weight: 313.83. BOC Sciences 7
EHNA hydrochloride EHNA hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 81408-49-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 10
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