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| Product | Description | |
|---|---|---|
| Eicosapentaenoic Acid (Standard) | Eicosapentaenoic Acid (Standard) is the analytical standard of Eicosapentaenoic Acid. This product is intended for research and analytical applications. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EPA (Standard); Timnodonic acid (Standard). CAS No. 10417-94-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0660R. |  |
| Eicosyl ferulate | Eicosyl ferulate is isolated from Aristolochia kankauensis. Alternative Names: Icosyl 3-(4-hydroxy-3-methoxyphenyl)acrylate; Icosyl ferulate; Eicosanyl ferulate. CAS No. 133882-79-8. Molecular formula: C30H50O4. Mole weight: 474.726. |  |
| Eicosyltriethyl Ammonium bromide | Eicosyltriethyl Ammonium bromide. Group: Biochemicals. Alternative Names: N,N,N-Triethyl-1-eicosanaminium bromide; n-Eicosyltriethyl Ammonium bromide. Grades: Highly Purified. CAS No. 75222-49-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C26H56BrN. US Biological Life Sciences. |  Worldwide |
| EIDD-1931 | EIDD-1931 is a ribonucleoside analog that exhibits potential antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV. EIDD-1931 induces mutations in RNA virions, inhibiting SARS-CoV-2 and other coronavirus in mice and human airway epithelial cells. Alternative Names: N4-Hydroxycytidine; N(4)-Hydroxycytidine; Uridine, 4-oxime; Beta-D-N4-hydroxycytidine. Grades: 99.73%. CAS No. 3258-2-4. Molecular formula: C9H13N3O6. Mole weight: 259.22. | |
| EIDD-1931 | EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: β-D-N4-hydroxycytidine; NHC. CAS No. 3258-2-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125033. | |
| EIDD-1931 | EIDD-1931 Inhibitor. Uses: Scientific use. Product Category: T8498. CAS No. 3258-2-4. |  |
| EIDD-2749 | 4'-Fluorouridine is an orally active RdRp inhibitor. It effectively blocks the replication of RSV and SARS-CoV-2. Alternative Names: 4'-fluorouridine;1613589-24-4;4'-C-Fluoro-uridine;1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione;1613591-91-5;SCHEMBL6839661;RDCYLPRXPILMRP-JVZYCSMKSA-N;AMY30709;EX-A6732;DA-70078;MS-23688;4'-fluorouridine (4'-FlU, EIDD-2749)?;1-((2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grades: 98%. CAS No. 1613589-24-4. Molecular formula: C9H11FN2O6. Mole weight: 262.19. | |
| EIDD-2749 | EIDD-2749 (4'-Fluorouridine) is an orally active RdRp inhibitor. EIDD-2749 effectively blocks the replication of RSV and SARS-CoV-2. EIDD-2749 also exhibits activity against HCV and lymphocytic choriomeningitis virus (LCMV). EIDD-2749 is a promising oral therapeutic candidate for COVID-19 and is also suitable for research on other RNA viruses[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4'-FlU; 4'-Fluorouridine. CAS No. 1613589-24-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146246. | |
| EIDD-2801 | EIDD-2801, derived from N4-hydroxycytidine, is an oral bioavailable broad-spectrum antiviral compound that is effective against SARS-CoV2 infection. Uses: Antiviral agents. Alternative Names: Molnupiravir; EIDD 2801; EIDD2801; MK-4482; WHO 11853; N4-Hydroxycytidine, 5'-isopropyl ester; beta-D-N4 Hydroxycytidine-5'-isopropyl ester; Uridine, 4-oxime, 5'-(2-methylpropanoate), (4Z)-; EIDD 1931-isopropyl ester; Lagevrio; MK-4482; β-D-N4 hydroxycytidine-5'-isopropyl ester. Grades: 95%. CAS No. 2492423-29-5. Molecular formula: C13H19N3O7. Mole weight: 329.31. | |
| eIF2α Antibody [C14N24] | EIF2S1,eIF2α. Group: Antibodies. Alternative Names: EIF2S1,eIF2α. Pack Sizes: 20ul. Product ID: F0316. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| eIF4A3-IN-1 | eIF4A3-IN-1 is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor. It binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD. Alternative Names: eIF4A3-IN-1; 2095486-67-0; CHEMBL4073833; BDBM50265561; AKOS040733081; MS-30511; HY-101513; CS-0021616; 3-[4-[(3S)-4-(4-bromobenzoyl)-3-(4-chlorophenyl)piperazine-1-carbonyl]-5-methylpyrazol-1-yl]benzonitrile. Grades: 99%. CAS No. 2095486-67-0. Molecular formula: C29H23BrClN5O2. Mole weight: 588.88. | |
| eIF4A3-IN-1 | eIF4A3-IN-1 is a selective eIF4A3 inhibitor (IC50: 0.26 μM; Kd: 0.043 μM) with cellular nonsense-mediated RNA decay (NMD) inhibitory activity. eIF4A3-IN-1 can specifically bind to the non-ATP binding site of eIF4A3. eIF4A3-IN-1 has anti-tumor and analgesic activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095486-67-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101513. | |
| eIF4A3-IN-18 | eIF4A3-IN-18 (compound 74) is a Silvestrol (HY-13251) analogue. eIF4A3-IN-18 interferes the assembling of eIF4F translation complex with EC50 values of 0.8, 35 and 2 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-18 also has cytotoxicity to RMPI-8226 cells with an LC50 of 0.06 nM. eIF4A3-IN-18 can be used for the research of human cancer pathogenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1402931-84-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-148452. | |
| eIF4A3-IN-2 | eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095677-20-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101785. | |
| eIF4A3-IN-5 | eIF4A3-IN-5, a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII, has the potential to study eIF4A dependent diseases, including cancer. (Extracted from patent US20170145026A1). Alternative Names: 6H-Cyclopenta[4,5]furo[3,2-c]pyridine-7-carboxylic acid, 5a-(4-cyanophenyl)-5a,7,8,8a-tetrahydro-8,8a-dihydroxy-1,3-dimethoxy-6-phenyl-, (5aR,6S,7R,8R,8aS)-. CAS No. 2100145-31-9. Molecular formula: C26H22N2O7. Mole weight: 474.46. | |
| eIF4E-IN-1 | eIF4E-IN-1, a potent eIF4E inhibitor, inhibits immunosuppression components such as the immune checkpoint proteins PD-1, PD-L1, LAG3, TIM3, and/or IDO, in order to inhibit or release immunosuppression in certain diseases, such as cancer and infectious diseases. (Extracted from patent WO2021003194A1, compound Y). Alternative Names: Thieno[3,2-b]pyridine-3-carboxylic acid, 7-[5-chloro-2-[2-[5-cyano-2-methyl-6-(4-methyl-1-piperazinyl)-4-oxo-7-(trifluoromethyl)-3(4H)-quinazolinyl]ethoxy]phenyl]-5-methyl-. CAS No. 2573979-31-2. Molecular formula: C33H28ClF3N6O4S. Mole weight: 697.13. | |
| eIF4E-IN-2 | eIF4E-IN-2 is a potent inhibitor of eukaryotic initiation factor 4e (eIF4e) with an IC50 of 13 nM. eIF4E-IN-2 inhibits MDA-MB-361 cells proliferation. eIF4E-IN-2 can be used for the study of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2575840-38-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-145262. | |
| EIPA | EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na+/H+-exchanger 3 (NHE3). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L593754; MH 12-43; Ethylisopropylamiloride. CAS No. 1154-25-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840. | |
| EIPA | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Uses: Epithelial sodium channel blockers. Alternative Names: Ethylisopropylamiloride; L 593754; MH 12-43; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide. Grades: ≥98% by HPLC. CAS No. 1154-25-2. Molecular formula: C11H18ClN7O. Mole weight: 299.76. | |
| EIPA hydrochloride | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Alternative Names: L593754 hydrochloride; L 593754 hydrochloride; L-593754 hydrochloride; Ethylisopropylamiloride hydrochloride; MH 12-43 hydrochloride; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide hydrochloride. CAS No. 1345839-28-2. Molecular formula: C11H19Cl2N7O. Mole weight: 336.22. | |
| EIPA hydrochloride | EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na+/H+-exchanger 3 (NHE3). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma[1][2][3][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L593754 hydrochloride; MH 12-43 hydrochloride; Ethylisopropylamiloride hydrochloride. CAS No. 1345839-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840A. | |
| EIPA (L593754) | EIPA (L593754; MH 12-43) acts as an inhibitor of macropinocytosis and sodium-hydrogen exchangers(NHE) (IC50=0.033μg/mL). EIPA blocks the activity of Na(+)/H(+) exchanger, which are plasma membrane proteins implicated in all forms of macropinocytosis. Group: Inhibitors. Alternative Names: L593754; MH 12-43. CAS No. 1154-25-2. Pack Sizes: 5mg. Product ID: S9849. Formula: C11H18ClN7O. Smiles: CCN(C(C)C)C1=C(Cl)N=C(C(=N1)N)C(=O)NC(N)=N. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| E-isomer Cefmenoxime impurity | E-isomer Cefmenoxime impurity. Uses: For analytical and research use. Alternative Names: (6R,7R)-7-((E)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Molecular formula: C16H17N9O5S3. Mole weight: 511.56. Catalog: APB04428. |  |
| EIT hydrobromide | EIT hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 1071-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ekatetrone | It is produced by the strain of Streptomyces aureofaciens. It can inhibit the protein and nucleic acid synthesis of Ehrlician ascites cancer cells, and has no anti-bacterial and anti-yeast effect. Alternative Names: (+)-2-(10,12-dihydroxy-3,6,11-trioxo-3,4,6,11-tetrahydro-1H-naphtho[2,3-g]isochromen-1-yl)acetamide; 1,8-Dihydroxy-2-(1'-hydroxy-2'-carbamoyl)ethyl-9,10-anthraquinone 3-acetic acid lactone; (+)-Ekatetrone; (+)-3,4,6,11-Tetrahydro-10,12-dihydroxy-3,6,11-trioxo-1H-anthra[2,3-c]pyran-1-acetamide. CAS No. 12794-19-3. Molecular formula: C19H13NO7. Mole weight: 367.31. | |
| ELA-14 (human) | ELA-14 (human) is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Alternative Names: Elabela (19-32). CAS No. 1886973-05-2. Molecular formula: C75H119N25O17S2. Mole weight: 1707.03. | |
| ELA-14 (human) acetate | ELA-14 (human) acetate is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating the Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Alternative Names: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro-OH.CH3CO2H; L-pyroglutamyl-L-arginyl-L-arginyl-L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-L-proline acetate; Elabela (19-32) acetate; ELA (19-32) (human) acetate. Grades: ≥95%. Molecular formula: C77H123N25O19S2. Mole weight: 1767.09. | |
| ELA-21 (human) | ELA-21 (human) is an apelin receptor agonist with a pKi of 8.52. ELA-21 (human) completely inhibits Forskolin-induced cAMP production and stimulates β-arrestin recruitment with subnanomolar potencies. ELA-21 (human) is an agonist in G-protein-dependent and -independent pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2245073-05-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2249. | |
| Elabela(19-32) | Elabela(19-32) is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1886973-05-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2106. | |
| Elacestrant | Elacestrant (RAD1901) is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also can inhibit growth of ER+ breast cancer cell lines in vitro and in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAD1901. CAS No. 722533-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19822. | |
| Elacestrant dihydrochloride | Elacestrant dihydrochloride is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. It is also a selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Alternative Names: RAD1901 dihydrochloride; (R)-6-(2-(ethyl(4-(2-(ethylamino)ethyl)benzyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol dihydrochloride; 2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6R)-, hydrochloride (1:2). Grades: 98%. CAS No. 1349723-93-8. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. | |
| Elacestrant dihydrochloride | Elacestrant (RAD1901) dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant dihydrochloride also can inhibit growth of ER+ breast cancer cell lines in vitro and in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAD1901 dihydrochloride. CAS No. 1349723-93-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19822A. | |
| Elacestrant S enantiomer | Elacestrant S enantiomer is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Alternative Names: RAD1901 S enantiomer; 2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6S)-; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol. CAS No. 2309762-29-4. Molecular formula: C30H38N2O2. Mole weight: 458.63. | |
| Elacestrant S enantiomer dihydrochloride | Elacestrant S enantiomer dihydrochloride is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Alternative Names: RAD1901 S enantiomer dihydrochloride; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol dihydrochloride; 2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6S)-, hydrochloride (1:2). Grades: ≥95%. CAS No. 2309762-30-7. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. | |
| Elacridar | Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Alternative Names: GF120918; GF-120918; GF 120918; GF-120918A; GF120918A; GF 120918A; GG 918; D03968. Elacridar hydrochloride. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.654. | |
| Elacridar | Elacridar. Alternative Names: N-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide. CAS No. 143664-11-3. Purity: 98%. Product ID: ACM143664113. Molecular formula: C34H33N3O5. Mole weight: 563.6. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Elacridar | Elacridar is an orally active P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar can be used to examine the influence of efflux transporters on agent distribution to brain and the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GF120918; GW0918; GG918; GW120918. CAS No. 143664-11-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50879. | |
| Elacridar | Elacridar. Group: Biochemicals. Alternative Names: N-[4-[2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9, 10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918; GG 918. Grades: Highly Purified. CAS No. 143664-11-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C??H??N?O?, Molecular Weight: 563.64. US Biological Life Sciences. | Worldwide |
| Elacridar (GF120918) | Elacridar (GF120918, GW120918, GG918, GW0918) is a potent P-gp (MDR-1) and BCRP inhibitor. Group: Inhibitors. Alternative Names: GW120918, GG918, GW0918. CAS No. 143664-11-3. Pack Sizes: 10mg. Product ID: S7772. Formula: C34H33N3O5. Smiles: COC1=CC=CC2=C1NC3=C(C2=O)C=CC=C3C(=O)NC4=CC=C(C=C4)CCN5CCC6=CC(=C(C=C6C5)OC)OC. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Elacridar hydrochloride | Elacridar is an orally bioavailable inhibitor of P-glycoprotein (P-gp) and ABCG2. Alternative Names: Elacridar HCl; N-[4-[2-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-yl)ethyl]phenyl]-5-methoxy-9-oxo-10H-acridine-4-carboxamide hydrochloride. CAS No. 143851-98-3. Molecular formula: C34H33N3O5.HCl. Mole weight: 600.10. | |
| Elacridar hydrochloride | Elacridar hydrochloride (GF120918A) is an orally active P-glycoprotein (P-gp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar hydrochloride can be used to examine the influence of efflux transporters on agent distribution to brain and it can be used for the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GF120918A. CAS No. 143851-98-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-50880. | |
| Elacytarabine | Elacytarabine (CP-4055) is the lipophilic 5'-elaidic acid ester of the deoxycytidine analog cytosine arabinoside (cytarabine; Ara-C) with potential antineoplastic activity. As a prodrug, CP-4055 is converted intracellularly into cytarabine triphosphate by deoxycytidine kinase and subsequently competes with cytidine for incorporation into DNA, thereby inhibiting DNA synthesis. Compared to cytarabine, CP-4055 shows increased cellular uptake and retention, resulting in increased activation by deoxycytidine kinase to cytarabine triphosphate, decreased deamination and deactivation by deoxycytidine deaminase, and increased inhibition of DNA synthesis. This agent also inhibits RNA synthesis, an effect not seen with cytarabine. Alternative Names: CP-4055; CP 4055; CP4055; 5'-O-(Elaidoyl) 1-beta-D-arabinofuranosylcytosine; 5'-Oleoyl cytarabine; (E)-((2R,3S,4S,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-3,4-dihydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate. CAS No. 188181-42-2. Molecular formula: C27H45N3O6. Mole weight: 507.67. | |
| Elaeis guineensis oil | Elaeis guineensis oil. Alternative Names: Palm fruit oil. CAS No. 8002-75-3. Purity: 0.98. Product ID: CI-EO-0072. Molecular formula: C134H125N9O32S3. Mole weight: 2469.7 g/mol. Alfa Chemistry - ISO 9001:32057 Certified. | |
| Elafibranor | Elafibranor (GFT505) is a PPARα/δ agonist with EC50s of 45 and 175 nM, respectively. Elafibranor can be used for the study of primary biliary cholangitis[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GFT505. CAS No. 923978-27-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-16737. | |
| Elafibranor | Elafibranor is a dual PPARα/δ agonist. Elafibranor increases plasma HDL and expression of Acox1, a PPARα target gene, and decreases plasma triglycerides and total cholesterol in the liver of ApoE2-KI wild-type mice. Elafibranor is identified as a drug candidate for the treatment of cardiometabolic diseases such as diabetes, insulin resistance, dyslipidemia, and non-alcoholic fatty liver disease (NAFLD). Alternative Names: Propanoic acid, 2-[2,6-dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methyl-; 2-[2,6-Dimethyl-4-[(1E)-3-[4-(methylthio)phenyl]-3-oxo-1-propen-1-yl]phenoxy]-2-methylpropanoic acid; (E)-1-[4-(Methylthio)phenyl]-3-[3,5-dimethyl-4-[(carboxydimethylmethyl)oxy]phenyl]prop-2-en-1-one; GFT 505; GFT-505; GFT505. Grades: ≥95%. CAS No. 923978-27-2. Molecular formula: C22H24O4S. Mole weight: 384.49. | |
| Elagolix | Elagolix is a Gonadotropin-Releasing Hormone (GnRH) Antagonist. Elagolix inhibits gonadatropin releasing hormone (GnRH) receptors in the pituitary gland and ultimately reduces circulating sex hormone levels. To date, elagolix has been studied in over 20 clinical trials totaling more than 1,000 subjects. A Phase 2a trial of elagolix for the treatment of uterine fibroids is also ongoing. Endometriosis can be a debilitating disease that affects millions of women around the world and the exploration of new treatments could offer other options for women with this disease. Alternative Names: Elagolix, Elagolix sodium, NBI-56418; NBI 56418; NBI56418. CAS No. 834153-87-6. Molecular formula: C32H30F5N3O5. Mole weight: 631.6. | |
| Elagolix Impurity 1 | Elagolix Impurity 1. Uses: For analytical and research use. Alternative Names: sodium (R)-4-((2-(3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)amino)butanoate. Molecular formula: C25H24F4N3NaO4. Mole weight: 529.46. Catalog: APB05845. | |
| Elagolix Impurity 10 | Elagolix Impurity 10. Uses: For analytical and research use. Alternative Names: 5-(2-fluoro-3-methoxyphenyl)-6-methyl-1-(2-(trifluoromethyl)benzyl)pyrimidine-2,4(1H,3H)-dione. Molecular formula: C20H16F4N2O3. Mole weight: 408.35. Catalog: APB05841. | |
| Elagolix Impurity 11 | Elagolix Impurity 11. Uses: For analytical and research use. Alternative Names: 1-(2-fluoro-6-(trifluoromethyl)benzyl)-5-(3-methoxyphenyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular formula: C20H16F4N2O3. Mole weight: 408.35. Catalog: APB05839. | |
| Elagolix Impurity 12 | Elagolix Impurity 12. Uses: For analytical and research use. Alternative Names: (R)-N-(2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)-2-hydroxybenzamide. Molecular formula: C35H28F5N3O5. Mole weight: 665.61. Catalog: APB05840. | |
| Elagolix Impurity 13 | Elagolix Impurity 13. Uses: For analytical and research use. Alternative Names: 2,2'-difluoro-3,3'-dimethoxy-1,1'-biphenyl. CAS No. 2316733-82-9. Molecular formula: C14H12F2O2. Mole weight: 250.24. Catalog: APB2316733829. | |
| Elagolix Impurity 14 | Elagolix Impurity 14. Uses: For analytical and research use. Alternative Names: 3-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular formula: C13H10F4N2O2. Mole weight: 302.22. Catalog: APB05838. | |
| Elagolix Impurity 15 | Elagolix Impurity 15. Uses: For analytical and research use. Alternative Names: 6-methyl-1-(2-(trifluoromethyl)benzyl)pyrimidine-2,4(1H,3H)-dione. Molecular formula: C13H11F3N2O2. Mole weight: 284.23. Catalog: APB05837. | |
| Elagolix Impurity 16 | Elagolix Impurity 16. Uses: For analytical and research use. Alternative Names: 1-(2-fluoro-4-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular formula: C13H10F4N2O2. Mole weight: 302.22. Catalog: APB05836. | |
| Elagolix Impurity 17 | Elagolix Impurity 17. Uses: For analytical and research use. Alternative Names: 1-(4-fluoro-2-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular formula: C13H10F4N2O2. Mole weight: 302.22. Catalog: APB05835. | |
| Elagolix Impurity 19 | Elagolix Impurity 19. Uses: For analytical and research use. Alternative Names: 3-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. CAS No. 2354391-45-8. Molecular formula: C13H10F4N2O2. Mole weight: 302.22. Catalog: APB2354391458. | |
| Elagolix Impurity 19Q | Elagolix Impurity 19Q. Uses: For analytical and research use. CAS No. 2409132-60-9. Molecular formula: C36H36F5N3O7. Mole weight: 717.69. Catalog: APB2409132609. | |
| Elagolix Impurity 2 | Elagolix Impurity 2. Uses: For analytical and research use. CAS No. 2409132-64-3. Molecular formula: C38H40F5N3O6. Mole weight: 729.75. Catalog: APB2409132643. | |
| Elagolix Impurity 2 | Elagolix Impurity 2. Uses: For analytical and research use. Alternative Names: 3-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular formula: C13H10F4N2O2. Mole weight: 302.22. Catalog: APB05844. | |
| Elagolix Impurity 20 | Elagolix Impurity 20. Uses: For analytical and research use. Alternative Names: (R)-4,4'-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)azanediyl)dibutanoic acid. Molecular formula: C36H36F5N3O7. Mole weight: 717.68. Catalog: APB05833. | |
| Elagolix Impurity 21 | Elagolix Impurity 21. Uses: For analytical and research use. Alternative Names: 1-(2-fluoro-4-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular formula: C13H10F4N2O2. Mole weight: 302.22. Catalog: APB05832. | |
| Elagolix Impurity 22 | Elagolix Impurity 22. Uses: For analytical and research use. Alternative Names: (R)-4-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)(hydroxy)amino)butanoic acid. Molecular formula: C32H30F5N3O6. Mole weight: 647.59. Catalog: APB05834. | |
| Elagolix Impurity 23 | Elagolix Impurity 23. Uses: For analytical and research use. Alternative Names: 5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methyl-3-(2-oxo-2-phenylethyl)pyrimidine-2,4(1H,3H)-dione. CAS No. 2409132-61-0. Molecular formula: C28H21F5N2O4. Mole weight: 544.47. Catalog: APB2409132610. | |
| Elagolix Impurity 24 | Elagolix Impurity 24. Uses: For analytical and research use. CAS No. 2486454-63-9. Molecular formula: C32H30F5N3O6. Mole weight: 647.6. Catalog: APB2486454639. | |
| Elagolix Impurity 24 | Elagolix Impurity 24. Uses: For analytical and research use. Alternative Names: 5-chloro-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methylpyrimidine-2,4(1H,3H)-dione. Molecular formula: C13H9ClF4N2O2. Mole weight: 336.67. Catalog: APB05831. | |
| Elagolix Impurity 25 | Elagolix Impurity 25. Uses: For analytical and research use. Alternative Names: (S)-diethyl 4,4'-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)azanediyl)dibutanoate. Molecular formula: C40H44F5N3O7. Mole weight: 773.79. Catalog: APB05830. | |
| Elagolix Impurity 26 | Elagolix Impurity 26. Uses: For analytical and research use. CAS No. 1092070-97-7. Molecular formula: C33H32F5N3O5. Mole weight: 645.63. Catalog: APB1092070977. | |
| Elagolix Impurity 26 | Elagolix Impurity 26. Uses: For analytical and research use. Alternative Names: sodium (R)-4,4'-((2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)azanediyl)dibutanoate. Molecular formula: C36H34F5N3Na2O7. Mole weight: 761.65. Catalog: APB05829. | |
| Elagolix Impurity 27 | Elagolix Impurity 27. Uses: For analytical and research use. Alternative Names: (R)-N-(2-(5-(2-fluoro-3-methoxyphenyl)-3-(2-fluoro-6-(trifluoromethyl)benzyl)-4-methyl-2,6-dioxo-2,3-dihydropyrimidin-1(6H)-yl)-1-phenylethyl)formamide. Molecular formula: C29H24F5N3O4. Mole weight: 573.52. Catalog: APB05827. | |
| Elagolix Impurity 28 | Elagolix Impurity 28. Uses: For analytical and research use. Alternative Names: (R)-5-(2-fluoro-3-methoxyphenyl)-1-(2-fluoro-6-(trifluoromethyl)benzyl)-6-methyl-3-(2-(2-oxopyrrolidin-1-yl)-2-phenylethyl)pyrimidine-2,4(1H,3H)-dione. Molecular formula: C32H28F5N3O4. Mole weight: 613.59. Catalog: APB05828. | |
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