American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

Search for products or services, then visit the suppliers website for prices or more information.

Product
Eliglustat Hemitartrate Eliglustat Hemitartrate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 928659-70-5. Molecular Formula: C23H36N2O4·1/2(C4H6O6). Mole Weight: 479.6. Catalog: APB928659705. Alfa Chemistry Analytical Products 3
Eliglustat Impurity 1 Eliglustat Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2R)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-2-(((S)-2-hydroxy-1-phenylethyl)amino)-3-(pyrrolidin-1-yl)propan-1-ol. CAS No. 491833-27-3. Molecular Formula: C23H30N2O4. Mole Weight: 398.5. Catalog: APB491833273. Alfa Chemistry Analytical Products 2
Eliglustat Impurity 2 Eliglustat Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-((2R,3R)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-hydroxy-2-octanamidopropyl)pyrrolidine 1-oxide. CAS No. 2137145-62-9. Molecular Formula: C23H36N2O5. Mole Weight: 420.54. Catalog: APB2137145629. Alfa Chemistry Analytical Products 2
Eliglustat Impurity 3 Eliglustat Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (2S,3R)-3-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-hydroxy-2-(((S)-2-hydroxy-1-phenylethyl)amino)-1-(pyrrolidin-1-yl)propan-1-one. CAS No. 491833-26-2. Molecular Formula: C23H28N2O5. Mole Weight: 412.48. Catalog: APB491833262. Alfa Chemistry Analytical Products 2
Eliglustat Impurity 4 Eliglustat Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (1R,2R)-2-amino-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-3-(pyrrolidin-1-yl)propan-1-ol. Molecular Formula: C15H22N2O3. Mole Weight: 278.35. Catalog: APB05846. Alfa Chemistry Analytical Products 4
Eliglustat Impurity 5 Eliglustat Impurity 5. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-((1S,2S)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)octanamide. CAS No. 1092472-70-2. Molecular Formula: C23H36N2O4. Mole Weight: 404.54. Catalog: APB1092472702. Alfa Chemistry Analytical Products
Eliglustat Impurity 6 Eliglustat Impurity 6. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: N-((1S,2R)-1-(2,3-dihydrobenzo[b][1,4]dioxin-6-yl)-1-hydroxy-3-(pyrrolidin-1-yl)propan-2-yl)octanamide. CAS No. 1092472-66-6. Molecular Formula: C23H36N2O4. Mole Weight: 404.54. Catalog: APB1092472666. Alfa Chemistry Analytical Products
Elimusertib Elimusertib (BAY-1895344) is a potent, orally active and selective ATR inhibitor with an IC 50 of 7 nM. Elimusertib has anti-tumor activity [1] [2]. Elimusertib can be used for the research of solid tumors and lymphomas [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: BAY 1895344. CAS No. 1876467-74-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101566. MedChemExpress MCE
Elimusertib free base Elimusertib, also known as BAY-1895344, is a potent and selective ATM inhibitor. BAY 1895344 shows potent anti-tumor efficacy in monotherapy and strong combination potential with the targeted alpha therapy Radium-223 dichloride. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Elimusertib, free base; BAY-1895344; BAY 1895344; BAY1895344. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1876467-74-1. Molecular formula: C20H21N7O. Mole weight: 375.44. Purity: >98%. IUPACName: (R)-3-methyl-4-(4-(1-methyl-1H-pyrazol-5-yl)-8-(1H-pyrazol-5-yl)-1,7-naphthyridin-2-yl)morpholine. Canonical SMILES: CN1N=CC=C1C2=CC(N3[C@H](C)COCC3)=NC4=C(C5=CC=NN5)N=CC=C24. Product ID: ACM1876467741. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Elinafide Elinafide, an isoquinoline derivative, has been found to be a Type II DNA topoisomerase inhibitor that was once developed in anticancer studies. Synonyms: Elinafide; UNII-HL580335SI; Elinafide [INN]; 2- [2- [3- [2- (1, 3-dioxobenzo [de]isoquinolin-2-yl) ethylamino]propylamino]ethyl]benzo [de]isoquinoline-1, 3-dione; LU-79553. Grades: 98%. CAS No. 162706-37-8. Molecular formula: C31H28N4O4. Mole weight: 520.59. BOC Sciences 10
Elinogrel Elinogrel is a P2Y12 antagonist displaying antiplatelet activity. Synonyms: 5-Chloro-N-[[[4-[6-Fluoro-1,4-dihydro-7-(methylamino)-2,4-dioxo-3(2H)-quinazolinyl]phenyl]amino]carbonyl]-2-thiophenesulfonamide. Grades: ≥98% by HPLC. CAS No. 936500-94-6. Molecular formula: C20H15ClFN5O5S2. Mole weight: 523.95. BOC Sciences 10
Elinogrel Elinogrel (PRT060128) is a potent, direct acting, competitive, and reversible platelet P2Y 12 antagonist ( IC 50 =20 nM). It is orally and intravenously available and has potent antiplatelet effects [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: PRT060128. CAS No. 936500-94-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-11021. MedChemExpress MCE
Elinogrel Elinogrel, also known as PRT 060128, is P2Y12 inhibitor. Similarly to ticagrelor and in contrast to clopidogrel, elinogrel was a reversible inhibitor that acted fast and short (for about 12 hours), and it was not a prodrug but pharmacologically active itself. The substance was used in form of its potassium salt, intravenously for acute treatment and orally for long-term treatment. Development was terminated in 2012. Uses: Designed for use in research and industrial production. Additional or Alternative Names: PRT 060128; PRT-060128; PRT060128; Elinogrel. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 936500-94-6. Molecular formula: C20H15ClFN5O5S2. Mole weight: 523.94. Purity: >98%. IUPACName: 5-chloro-N-((4-(6-fluoro-7-(methylamino)-2,4-dioxo-1,4-dihydroquinazolin-3(2H)-yl)phenyl)carbamoyl)thiophene-2-sulfonamide. Canonical SMILES: O=C(NC1=CC=C(N2C(NC3=C(C=C(F)C(NC)=C3)C2=O)=O)C=C1)NS(=O)(C4=CC=C(Cl)S4)=O. Product ID: ACM936500946-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Elinogrel Elinogrel. Group: Biochemicals. Grades: Purified. CAS No. 936500-94-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
Elintaal Elintaal (Acetaldehyde Ethyl Linalyl Acetal). CAS No. 40910-49-4. VIGON Item # 503213. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. Vigon
America & Internationally
Elinzanetant Elizanetant (NT-814) is an orally active, selective NK-1,3 receptor antagonist. Elizanetant can reduce the levels of estradiol and progesterone, and is used in the study of vascular motor symptoms and sleep disorders related to menopause in women [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: NT-814; BAY3427080. CAS No. 929046-33-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109171. MedChemExpress MCE
Elipovimab Elipovimab is a potent broadly neutralizing HIV-1 antibody for the targeted elimination of HIV-infected cells [1]. Uses: Scientific research. Group: Inhibitory antibodies. CAS No. 2101210-43-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99937. MedChemExpress MCE
Eliprodil Eliprodil(SL-820715) is a non-competitive NR2B-NMDA receptor antagonist(IC50=1 uM), less potent for NR2A- and NR2C-containing receptors(IC50> 100 uM). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SL-820715. CAS No. 119431-25-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12881. MedChemExpress MCE
Eliprodil Eliprodil. Group: Biochemicals. Grades: Purified. CAS No. 119431-25-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
Eliprodil Eliprodil, a NR2B-NMDA receptor antagonist, was found to have neuroprotective activity in study of ischemia. Uses: Eliprodil is a nr2b-nmda receptor antagonist that was found to have neuroprotective activity in study of ischemia. Synonyms: -(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, SL-82,0715; SL82,0715; SL 82,0715; SL-820715; SL820715; SL 820715; Eliprodil. Grades: 95%. CAS No. 119431-25-3. Molecular formula: C20H23ClFNO. Mole weight: 347.85. BOC Sciences 9
Eliprodil (alpha-(4-Chlorophenyl)-4-[(4-fluorophenyl)methyl]-1-piperidineethanol, NMDA Antagonist IX) A negative allosteric modulator selective for NR2B containingnMDA receptors (IC50 = 1, >100, and >100uM for NR2B, NR2A, and NR2C, respectively). Also a potent ligand for alpha1 receptor (Ki = 0.013uM), one of the two types of unique non-opioid, non-phencyclidine brain alpha receptors. Blocks neuronal voltage-gated Ca2+. Group: Biochemicals. Grades: Highly Purified. CAS No. 119431-25-3. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
elisabethatriene synthase Requires Mg2+ or less efficiently Mn2+. The enzyme is also able to use farnesyl diphosphate and geranyl diphosphate. Group: Enzymes. Synonyms: elisabethatriene cyclase. Enzyme Commission Number: EC 4.2.3.41. CAS No. 334022-59-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5200; elisabethatriene synthase; EC 4.2.3.41; 334022-59-2; elisabethatriene cyclase. Cat No: EXWM-5200. Creative Enzymes
Elisidepsin Elisidepsin is a marine-derived, synthetic cyclic depsipeptide with potential antineoplastic activity. Elisidepsin is a derivative of a natural marine compound that belongs to a family of dehydro aminobutyric acid-containing peptides (kahalalides) isolated from the herbivorous marine mollusk Elysia rufescens. Although the primary mechanism of action has yet to be elucidated, this agent exhibits anti-proliferative activity in a wide variety of cancer cell types, including breast, colon, pancreas, lung, and prostate; it appears to induce oncolytic rather than apoptotic cell death. Synonyms: PM-02734; N-[(4S)-4-methylhexanoyl]-D-valyl-L-threonyl-L-valyl-D-valyl-D-prolyl-L-ornithyl-N-{(3S,6Z,9S,12R,15R,18R,19R)-9-benzyl-15-[(2S)-butan-2-yl]-6-ethylidene-3,12-diisopropyl-19-methyl-2,5,8,11,14,17-hexaoxo-1-oxa-4,7,10,13,16-pentaazacyclononadecan-18-yl}-D-alloisoleucinamide. CAS No. 681272-30-0. Molecular formula: C75H124N14O16. Mole weight: 1477.90. BOC Sciences 11
Elizabethin It is produced by the strain of Streptomyces elizabethii. It has antifungal activity. CAS No. 78361-81-6. Molecular formula: C35H58O12. Mole weight: 670.83. BOC Sciences 5
Ellagicacid Ellagicacid. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone. Product Category: Material of cosmetics. Appearance: Yellow-brown fluid fine powder. CAS No. 476-66-4. Molecular formula: C14H6O8. Mole weight: 302.19. Product ID: ACM476664. Alfa Chemistry — ISO 9001:2015 Certified. Categories: Ellagic acid. Alfa Chemistry. 2
Ellagic acid Natural Compounds; Herbal Medicinal Products Standards; Fluorescence/Luminescence Spectroscopy. Uses: For analytical and research use. Group: Reagents. CAS No. 476-66-4. Alfa Chemistry Analytical Products
Ellagic acid 25g Pack Size. Group: Aroma Chemicals, Biochemicals, Flavours and Fragrance Materials. Formula: C14H6O8. CAS No. 476-66-4. Prepack ID 23304412-25g. Molecular Weight 302.19. See USA prepack pricing. Molekula Americas
Ellagic acid Ellagic acid. Synonyms: 4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone, Alizarin Yellow, Benzoaric acid, Elagostasine, Eleagic acid, Gallogen, Lagistase. CAS No. 476-66-4. Product ID: CDC10-0049. Molecular formula: C14H6O8 xH2O. Category: Antioxidant Cosmetic Chemicals. Product Keywords: Cosmetic Ingredients; Antioxidant Cosmetic Chemicals; Ellagic acid; CDC10-0049; 476-66-4; C14H6O8 xH2O; 4,4',5,5',6,6'-Hexahydroxydiphenic acid 2,6,2',6'-dilactone, Alizarin Yellow, Benzoaric acid, Elagostasine, Eleagic acid, Gallogen, Lagistase; 207-508-3; MFCD00006914; 476-66-4. Purity: ≥95% (HPLC). Color: Tan to gray. EC Number: 207-508-3. Physical State: Powder. Solubility: 1 M NaOH: 10 mg/mL. Quality Level: 200. Storage: 2-8°C. Boiling Point: 363.24°C (rough estimate). Melting Point: ≥350 °C. Density: 1.667 g/mL. CD Formulation
Ellagic acid Ellagic acid is a natural antioxidant, and acts as a potent and ATP-competitive inhibitor of CK2 and SHP2 , with an IC 50 of 40 nM and a K i of 20 nM. Uses: Scientific research. Group: Natural products. CAS No. 476-66-4. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-B0183. MedChemExpress MCE
Ellagic acid Ellagic acid - Product ID: NST-10-60. Category: Polyphenols. Alternative Names: Benzoaric acid ; 4,4',5,5',6,6'-Hexahydroxydiphenic acid. Purity: 98%. Test method: HPLC. CAS No. 476-66-4. Pack Sizes: 50g, 100g, 250g, 500g. Appearance: Grey to brown Powder. Molecular formula: C14H6O8. Mole weight: 302.2. Storage: +2 … +8 °C. NATURE SCIENCE TECHNOLOGIES
Ellagic acid Ellagic acid appears as cream-colored needles (from pyridine) or yellow powder. Odorless. (NTP, 1992);Solid. Group: Monomers. Alternative Names: Eleagicacid. CAS No. 476-66-4. Product ID: 6, 7, 13, 14-Tetrahydroxy-2, 9-dioxatetracyclo[6.6.2.04, 16.011, 15]hexadeca-1(15), 4, 6, 8(16), 11, 13-hexaene-3, 10-dione. Molecular formula: 302.19. Mole weight: C14H6O8. C1=C2C3=C (C (=C1O)O)OC (=O)C4=CC (=C (C (=C43)OC2=O)O)O. InChI=1S/C14H6O8/c15-5-1-3-7-8-4 (14 (20)22-11 (7)9 (5)17)2-6 (16)10 (18)12 (8)21-13 (3)19/h1-2, 15-18H. AFSDNFLWKVMVRB-UHFFFAOYSA-N. 98%. Alfa Chemistry Materials 4
Ellagic Acid Ellagic Acid is a phenol antioxidant found naturally in various fruits and vegetables. Ellagic Acid was shown to exhibit high levels of antiproliferative and antioxidant properties in studies, which suggests its potential health benefits following ellagic acid consumption. Group: Biochemicals. Alternative Names: Alizarin yellow; Alizarine Yellow; Benzoaric acid; C.I. 55005; C.I. 75270; Elagostasine; Eleagic acid; G 91006; Gallogen; Gallogen (astringent); LDN 0097519; Lagistase. Grades: Highly Purified. CAS No. 476-66-4. Pack Sizes: 25g. Molecular Formula: C??H?O?, Molecular Weight: 302.19. US Biological Life Sciences. USBiological 7
Worldwide
Ellagic acid, 96% Ellagic acid appears as cream-colored needles (from pyridine) or yellow powder. Odorless. (NTP, 1992);Solid. Group: Monomers. CAS No. 476-66-4. Product ID: 6, 7, 13, 14-tetrahydroxy-2, 9-dioxatetracyclo[6.6.2.04, 16.011, 15]hexadeca-1(15), 4, 6, 8(16), 11, 13-hexaene-3, 10-dione. Molecular formula: 302.19g/mol. Mole weight: C14H6O8. C1=C2C3=C (C (=C1O)O)OC (=O)C4=CC (=C (C (=C43)OC2=O)O)O. InChI=1S/C14H6O8/c15-5-1-3-7-8-4 (14 (20)22-11 (7)9 (5)17)2-6 (16)10 (18)12 (8)21-13 (3)19/h1-2, 15-18H. AFSDNFLWKVMVRB-UHFFFAOYSA-N. Alfa Chemistry Materials 4
Ellagic acid dihydrate Ellagic acid dihydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 133039-73-3. Pack Sizes: 100mg, 250mg. Molecular Formula: C14H6O8.2H2O, Molecular Weight: 338.223. US Biological Life Sciences. USBiological 5
Worldwide
Ellagic Acid (Hydrate) Ellagic acid hydrate is a natural antioxidant, and acts as a potent and ATP-competitive CK2 inhibitor, with an IC50 of 40 nM and a Ki of 20 nM. Uses: Designed for use in research and industrial production. Product Category: Inhibitors. CAS No. 314041-08-2. Molecular formula: C14H8O9. Mole weight: 320.21. Product ID: ACM314041082-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Ellipticine Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 71795. CAS No. 519-23-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-15753. MedChemExpress MCE
Ellipticine Ellipticine (NSC 71795) is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5,11-DIMETHYLPYRIDO[4,3-B]CARBAZOLE;5,11-DIMETHYLPYRIDO[4.3:B]CARBAZOLE;5,11-DIMETHYL-6H-PYRIDO[4,3-B]CARBAZOLE;ELLIPTICINE;3-b)carbazole,5,11-dimethyl-6h-pyrido(;icig770;ELLIPTICINE, FOR FLUORESCENCE;ELLIPTICINE(RG). Product Category: Inhibitors. CAS No. 519-23-3. Molecular formula: C17H14N2. Mole weight: 246.31. Density: 1.257±0.06 g/cm³ (20 ºC 760 Torr). Product ID: ACM519233. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Ellipticine hydrochloride Ellipticine (NSC 71795) hydrochloride is a potent antineoplastic agent; inhibits DNA topoisomerase II activities. Uses: Scientific research. Group: Natural products. Alternative Names: NSC 71795 hydrochloride. CAS No. 5081-48-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15753A. MedChemExpress MCE
Ellipticine (NSC 71795) Ellipticine is an alkaloid isolated from Apocyanaceae plants that exhibits antitumor activities by intercalating into DNA and/or inhibiting DNA topoisomerase II. It forms covalent adducts in DNA after being enzymatically activated with cytochrome P450 isoforms (e.g., CYP3A4, CYP1A1, or CYP1A2) or by peroxidases in target tissues. Ellipticine has been shown to inhibit the proliferation of human breast adenocarcinoma MCF-7 cells, leukemia HL-60 and CCRF-CEM cells, neuroblastoma IMR-32, UKF-NB-3, and UKF-NB-4 cells, and U87MG glioblastoma cells with IC50 values ranging from 0.27-4.7uM. Group: Biochemicals. Alternative Names: 5,11-dimethyl-6H-pyrido[4,3-b]carbazole, NSC 71795. Grades: Highly Purified. CAS No. 519-23-3. Pack Sizes: 5mg, 10mg, 25mg, 50mg. Molecular Formula: C17H14N2, Molecular Weight: 246.3. US Biological Life Sciences. USBiological 5
Worldwide
Elloramycin It is produced by the strain of Streptomyces olivaceus Tu 2353. It has weak activity against gram-positive bacteria, streptomycete and L-1210 leukemic cells, but has no effect on mouse leukemic P388 cells in vivo, and also has a strong inhibition of Streptomyces (including the production of bacteria themselves) activity. Synonyms: Elloramycin A; methyl (6aR,7S,10aR)-3-[(6-deoxy-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy]-6a,7,12-trihydroxy-8,10a-dimethoxy-1-methyl-6,10,11-trioxo-6,6a,7,10,10a,11-hexahydrotetracene-2-carboxylate; (6aR)-3-[(2-O,3-O,4-O-Trimethyl-6-deoxy-α-L-mannopyranosyl)oxy]-6,6a,7,10,10a,11-hexahydro-6aα,7α,12-trihydroxy-8,10aα-dimethoxy-1-methyl-6,10,11-trioxo-2-naphthacenecarboxylic acid methyl ester. CAS No. 97218-42-3. Molecular formula: C32H36O15. Mole weight: 660.62. BOC Sciences 5
Elmycin B ((1aR, 3S, 5bR, 11S, 11aR, 11bR)-10, 11, 11a-Trihydroxy-3-methyl-3, 4, 5b, 11, 11a, 11b-hexahydrotetrapheno[5, 6-b]oxirene-5, 6(1aH, 2H)-dion) Antibiotic. Antibacterial. Moderate cytotoxic. Group: Biochemicals. Grades: Highly Purified. CAS No. 128233-09-0. Pack Sizes: 1mg, 5mg. US Biological Life Sciences. USBiological 4
Worldwide
ELN 441958 ELN441958 is a novel, potent and selective bradykinin B1 receptor antagonist with Ki value of 0.26 nM. It competitively inhibited the binding of the agonist [3H]DAKD to the human B1 receptor in IMR-90 lung fibroblast cell membranes. It is highly selective for B1 over B2 receptors and >500/ 2000-fold selective for the B1 over μ/δ-opioid receptor. It also inhibited human μ-, δ-, κ- opioid receptors and muscarinic M1 receptor with Ki values of 0.13, 0.69, 1.5 and 0.37 μM, respectively. It exhibited good permeability and metabolic stability in vitro. It exhibited high oral bioavailability and moderate plasma half-lives in rats and rhesus monkeys. It does not inhibit the activation of the human bradykinin B2 receptor at concentrations up to 10 μM. It has a moderate clearance and volume of distribution in both species following i.v. administration, consistent with the high metabolic stability in rat, rhesus, and human microsomes. Uses: Eln441958 exhibited high oral bioavailability and moderate plasma half-lives. Synonyms: ELN441958; ELN 441958; ELN-441958;7-Chloro-2-[3-[[9-(pyridin-4-yl)-3,9-diazaspiro[5.5]undecan-3-yl]carbonyl]phenyl]-2,3-dihydroisoindol-1-one. Grades: >98%. CAS No. 913064-47-8. Molecular formula: C29H29ClN4O2. Mole weight: 501.02. BOC Sciences 10
ELN 484228 ELN 484228 is an α-Synuclein blocker with activity in cellular models of α-synuclein-mediated dysfunction such as Parkinson's Disease. Study showed that ELN484228 reduced synaptic levels of αSyn in neuronal cultures from both wild type rats and from transgenic mice overexpressing αSyn by not more than two-fold. Synonyms: ELN484228; ELN-484228; ELN 484228. N-(4-Fluorophenyl)benzenesulfonamide. Grades: 99%. CAS No. 312-63-0. Molecular formula: C12H10FNO2S. Mole weight: 251.28. BOC Sciences 9
ELND006 ELND006 is one of the newest molecules to be reported on regarding the testing of the β-amyloid hypothesis. ELND006 is a novel oral γ-secretase inhibitor. At the 2010 Alzheimer's Association International Conference on Alzheimer's Disease in which ELND006 was reported to have an in vitro IC50 = 0.34 nM against APP and IC50 = 5.3 nM versus Notch signaling. Synonyms: ELND006; ELND-006; ELND 006. (4R)-4-cyclopropyl-7,8-difluoro-5-[4-(trifluoromethyl)phenyl]sulfonyl-1,4-dihydropyrazolo[4,3-c]quinoline; UNII-7F5QGV49GL; ELND006; ELND-006; 959997-22-9; (R)-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo(4,3-c)quinoline; (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline; 7F5QGV49GL; SCHEMBL486044; GTPL7337; CHEMBL2396778. CAS No. 1333990-84-3. Molecular formula: C20H14F5N3O2S. Mole weight: 455.07. BOC Sciences 10
ELND007 ELND007 is a γ-secretase inhibitor. Synonyms: ELND007; ELND-007; ELND 007. (R)-4-cyclopropyl-8-fluoro-5-((6-(trifluoromethyl)pyridin-3-yl)sulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline; ELND007; ELND-007; ELND 007. CAS No. 1444006-79-4. Molecular formula: C19H14F4N4O2S. Mole weight: 438.08. BOC Sciences 10
Elobixibat Elobixibat is a potent and selective IBAT inhibitor under development for the treatment of chronic constipation and irritable bowel syndrome with constipation. Uses: Sodium-bile acid cotransporter-inhibitor. Synonyms: AZD-7806; AZD 7806; AZD7806; A 3309; A3309; A-3309; AJG-533; (2R)-N-[2-[[3,3-Dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl]oxy]acetyl]-2-phenylglycylglycine. Grades: ≥95%. CAS No. 439087-18-0. Molecular formula: C36H45N3O7S2. Mole weight: 695.89. BOC Sciences 9
Elobixibat Elobixibat (A 3309; AZD 7806) is an orally effective Apical Sodium-Dependent Bile (IBAT) inhibitor, with an IC 50 value of 0.53 nM (human IBAT ), 0.13 nM (mouse IBAT), 5.8 nM (canine IBAT). Elobixibat lowers LDL cholesterol, increases serum GLP-1, promotes colon motility, and has the potential to treat metabolic syndrome. Elobixibat can be used to study constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 3309; AZD 7806. CAS No. 439087-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15790. MedChemExpress MCE
Elobixibat hydrate Elobixibat hydrate is a potent ileal bile acid transporter (IBAT) inhibitor, with IC 50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. Elobixibat hydrate can be used for chronic idiopathic constipation (CIC) research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 3309 hydrate; AZD 7806 hydrate. CAS No. 1633824-78-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15790A. MedChemExpress MCE
Elomotecan Elomotecan (BN-80927) belongs to a novel family of camptothecin analogs, the homocamptothecins, developed on the concept of topoisomerase I (Topo I) inhibition and characterized by a stable seven-membered beta-hydroxylactone ring. Preclinical data reported here show that BN80927 retains Topo I poisoning activity in cell-free assay (DNA relaxation) as well as in living cells, in which in vivo complexes of topoisomerase experiments and quantification of DNA-protein-complexes stabilization, have confirmed the higher potency of BN80927 as compared with the Topo I inhibitor SN38. In addition, BN80927 inhibits Topo II-mediated DNA relaxation in vitro but without cleavable-complex stabilizatio...th assays, BN80927 is a very potent antiproliferative agent as shown by IC(50) values consistently lower than those of SN38 in tumor cell lines as well as in their related drug-resistant lines. BN80927 shows high efficiency in vivo in tumor xenograft studies using human androgen-independent prostate tumors PC3 and DU145. Altogether, these data strongly support the clinical development of BN80927. Synonyms: BN-80927; BN80927; BN 80927; R-1559; R1559; R 1559; (R)-9-chloro-5-ethyl-5-hydroxy-10-methyl-12-((4-methylpiperidin-1-yl)methyl)-4, 5-dihydrooxepino[3', 4':6, 7]indolizino[1, 2-b]quinoline-3, 15(1H, 13H)-dione. CAS No. 220998-10-7. Molecular formula: C29H32ClN3O4. Mole weight: 522.04. BOC Sciences 11
Elomotecan HCl salt Elomotecan, also referred to BN 80927 and R 1559, characterized by a stable seven-membered beta-hydroxylactone ring, is a DNA topoisomerase inhibitor. In vivo elomotecan shows high efficiency in vivo in tumor xenograft studies using human androgen-independent prostate tumors PC3 and DU145. Synonyms: 220997-99-9; 220998-10-7 (Elomotecan free base); (5R)-9-chloro-5-ethyl-5-hydroxy-10-methyl-12-[(4-methylpiperidin-1-yl)methyl]-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione hydrochloride (1:1). Grades: >98%. CAS No. 220997-99-9. Molecular formula: C29H33Cl2N3O4. Mole weight: 558.5. BOC Sciences 10
elongation factor 2 kinase Requires Ca2+ and calmodulin for activity. The enzyme can also be phosphorylated by the catalytic subunit of EC 2.7.11.11, cAMP-dependent protein kinase. Elongation factor 2 is phosphorylated in several cell types in response to various growth factors, hormones and other stimuli that raise intracellular Ca2+. Group: Enzymes. Synonyms: Ca/CaM-kinase III; calmodulin-dependent protein kinase III; CaM kinase III; eEF2 kinase; eEF2K; EF2K; STK19. Enzyme Commission Number: EC 2.7.11.20. CAS No. 116283-83-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3140; elongation factor 2 kinase; EC 2.7.11.20; 116283-83-1; Ca/CaM-kinase III; calmodulin-dependent protein kinase III; CaM kinase III; eEF2 kinase; eEF2K; EF2K; STK19. Cat No: EXWM-3140. Creative Enzymes
Elotuzumab Elotuzumab is a monoclonal antibody directed against the SLAMF7 receptor. Elotuzumab has no significant antimyeloma activity when given as a single agent with relapsed or refractory multiple myeloma (RRMM). Elotuzumab results in improved response and outcome when combined with other antimyeloma agents [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HuLuc 63; PDL 063; BMS 901608. CAS No. 915296-00-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9965. MedChemExpress MCE
ELOVL1-IN-2 ELOVL1-IN-2 is an inhibitor of ELOVL1 (elongation of very-long-chain-fatty acid 1). CAS No. 2761063-79-8. Molecular formula: C18H15FN2O. Mole weight: 294.3. BOC Sciences 8
Elpetrigine Elpetrigine, also known as GW 273293 and JZP-4, has a blocking effect on calcium channels and potassium channels which has been in clinical bipolar disorders and epilepsy. Synonyms: 3-(2,3,5-trichlorophenyl)pyrazine-2,6-diamine; GW273293; GW-273293; GW 273293; JZP-4; JZP 4; JZP4; Elpetrigine. Grades: >98%. CAS No. 212778-82-0. Molecular formula: C10H7Cl3N4. Mole weight: 289.54. BOC Sciences 10
Elphodex Acidic Kit Elphodex Acidic Kit. Group: Polysaccharide. Alfa Chemistry Materials 5
Elphodextrin Starter Kit Elphodextrin Starter Kit. Group: Polysaccharide. Alfa Chemistry Materials 5
ELQ-300 ELQ-300 is a potent and orally bioavailable antimalarial agent, and it is a novel inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (complex III in the electron transport chain). Synonyms: 6-chloro-7-methoxy-2-methyl-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-1H-quinolin-4-one. Grades: ≥98%. CAS No. 1354745-52-0. Molecular formula: C24H17ClF3NO4. Mole weight: 475.84. BOC Sciences 9
ELR510444 ELR510444 is a potent microtube disruptor with potential anticancer activity. ELR510444 has potent microtubule-disrupting activity, causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells. ELR510444 potently inhibited cell proliferation with an IC(50) value of 30.9 nM in MDA-MB-231 cells, inhibited the rate and extent of purified tubulin assembly, and displaced colchicine from tubulin, indicating that the drug directly interacts with tubulin at the colchicine-binding site. ELR510444 is not a substrate for the P-glycoprotein drug transporter and retains activity in βIII-tubulin-overexpressing cell lines, suggesting that it circumvents both clinically relevant mechanisms of drug resistance to this class of agents. ELR510444 also shows potent antitumor activity in the MDA-MB-231 xenograft model with at least a 2-fold therapeutic window. Synonyms: ELR510444; ELR-510444; ELR 510444. Grades: >98%. CAS No. 1233948-35-0. Molecular formula: C19H16N2O2S2. Mole weight: 368.47. BOC Sciences 10
Elranatamab Elranatamab (PF-06863135) is an anti- CD3E/TNFRSF17 human IgG2κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-06863135. CAS No. 2408850-14-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99909. MedChemExpress MCE
Elsamicin B Elsamicin B is produced by the strain of Actinomycetes J904-21. It is an antitumor antibiotic in the Chartreusin group. Aminoglycogen-deficient Elsamicin B shows only minimal antitumor activity. Synonyms: 10-[(3-C-Methyl-6-deoxy-β-D-galactopyranosyl)oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione; Benzo(h)(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,12-dione, 10-((6-deoxy-3-C-methyl-beta-D-galactopyranosyl)oxy)-6-hydroxy-1-methyl-; 6-Hydroxy-1-methyl-5,12-dioxo-5,12-dihydrobenzo[g][2]benzopyrano[5,4,3-cde][2]benzopyran-10-yl 6-deoxy-3-C-methylhexopyranoside. CAS No. 97068-31-0. Molecular formula: C26H22O10. Mole weight: 494.45. BOC Sciences 5
Elsamitrucin Elsamitrucin is produced by the strain of Actinomycetes J904-21. It has strong anti-tumor activity of mouse tumor cells such as leukemia P388, L1210 and melanoma B16, and its anti-tumor activity is 10-30 times stronger than Chartreusin. Uses: Antibiotics, antineoplastic. Synonyms: Elsamicin A. Grades: >95%. CAS No. 97068-30-9. Molecular formula: C33H35NO13. Mole weight: 653.63. BOC Sciences 6
Elsibucol Elsibucol, a metabolically stable derivative of probucol, inhibits atherosclerosis and preserves endothelial healing following arterial injury. In vitro, elsibucol reduces vascular smooth muscle cell proliferation without affecting cell viability. Synonyms: 4-[2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenoxy]butanoic acid; (4,2,6-di-tert-butyl-4-(1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl)-phenoxy-butyric acid); Elsibucol; AGI 1096; AGI1096; AGI-1096; Elsibucol; UNII-O7T92N1Y8T.elsibucol. Grades: >98%. CAS No. 216167-95-2. Molecular formula: C35H54O4S2. Mole weight: 602.94. BOC Sciences 9
Elsibucol Elsibucol. Uses: Designed for use in research and industrial production. Additional or Alternative Names: ELSIBUCOL. Product Category: Heterocyclic Organic Compound. CAS No. 216167-95-2. Molecular formula: C35H54O4S2. Mole weight: 602.94. Product ID: ACM216167952. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5
Elsilimomab Elsilimomab (B-E8) is a IgG1 monoclonal antibody against interleukin-6 (IL-6) , with a K D of 22 pM and an IC 50 of 1.4 nM. Elsilimomab can be used for the research of multiple myeloma, renal cell carcinoma, and rheumatoid arthritis (RA) [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: B-E8; Anti-IL-6 MAB B-E8; Anti-Human IL6 Recombinant Antibody. CAS No. 468715-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99287. MedChemExpress MCE
Elsinochrome A It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: (1r,2r)-1,2-diacetyl-4,11-dihydroxy-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-5,10-dione; 1alpha,2beta-Diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxybenzo[ghi]perylene-4,11-dione; Benzo(ghi)perylene-4,11-dione, 1,2-diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxy-, trans-. Grades: ≥98%. CAS No. 24568-67-0. Molecular formula: C30H24O10. Mole weight: 544.51. BOC Sciences 5
Elsinochrome B It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 1-Acetyl-5,10-dihydroxy-2-(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione. Grades: ≥98%. CAS No. 24512-58-1. Molecular formula: C30H26O10. Mole weight: 546.52. BOC Sciences 5
Elsinochrome C It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 5,10-Dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione; Benzo[ghi]perylene-4,11-dione,1,2-dihydro-5,10-dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-. Grades: ≥98%. CAS No. 24512-87-6. Molecular formula: C30H28O10. Mole weight: 548.54. BOC Sciences 5
Elsinochrome D It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 12,13-Dihydro-2-hydroxy-12,13-bis(1-hydroxyethyl)-1,5,6-trimethoxybenzo[1,12]perylo[2,3-d][1,3]dioxole-3,8-dione. Grades: ≥98%. CAS No. 32500-05-3. Molecular formula: C30H26O10. Mole weight: 546.52. BOC Sciences 5
Elsulfavirine Elsulfavirine is a new-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) being developed by Viriom for the treatment and prevention of human immunodeficiency virus (HIV) infections. It is the prodrug of the active compound VM-1500A, a small molecule selective NNRTI, which prevents HIV replication. In June 2017, elsulfavirine received its first global approval in Russia for the treatment of HIV-1 infections in combination with other antiretroviral medicines. Other formulations of this drug are also being evaluated in preclinical and phase II studies for the treatment of HIV infections and/or pre-exposure and post-exposure prophylaxis. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Elsulfavirine; Elpida. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 868046-19-9. Molecular formula: C24H17BrCl2FN3O5S. Mole weight: 629.28. Purity: >98%. IUPACName: N-(4-{2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]acetamido}-3-chlorobenzenesulfonyl)propanamide. Canonical SMILES: CCC(NS(=O)(C1=CC=C(NC(CC2=CC=C(Br)C(OC3=CC(C#N)=CC(Cl)=C3)=C2F)=O)C(Cl)=C1)=O)=O. Product ID: ACM868046199. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
Elsulfavirine Elsulfavirine is a reverse transcriptase inhibitors for HIV-1 infection and is a new anti-HIV agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-1206. CAS No. 868046-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109056. MedChemExpress MCE

Would you like to list your products on USA Chemical Suppliers?

Our database is helping our users find suppliers everyday.

Add Your Products