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| Product | Description | |
|---|---|---|
| Eicosapentaenoic acid ethyl ester | Eicosapentaenoic acid ethyl ester (EPA ethyl ester) is an orally active ω-3 fatty acid agent. Eicosapentaenoic acid ethyl ester could improve the activity of liver β-oxidase in vitro, reduce the level of liver total triglyceride, increase the content of liver triglyceride and phospholipid ω-3 fatty acid, and increase the total ω-3 fatty acid level in rats[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EPA ethyl ester; Ethyl eicosapentaenoate; AMR101. CAS No. 86227-47-6. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-B0747. |  |
| Eicosapentaenoic Acid Ethyl Ester | Eicosapentaenoic Acid Ethyl Ester. Group: Biochemicals. Alternative Names: EPA 90E; Incromega E 7010. Grades: Highly Purified. CAS No. 73310-10-8. Pack Sizes: 100mg. Molecular Formula: C22H34O2, Molecular Weight: 330.5. US Biological Life Sciences. |  Worldwide |
| Eicosapentaenoic Acid Impurity1 | Eicosapentaenoic Acid Impurity1. Uses: For analytical and research use. CAS No. 125827-49-8. Molecular formula: C22H34O2. Mole weight: 330.51. Catalog: APB125827498. |  |
| Eicosapentaenoic Acid Impurity10 | Eicosapentaenoic Acid Impurity10. Uses: For analytical and research use. CAS No. 123940-93-2. Molecular formula: C22H36O2. Mole weight: 332.53. Catalog: APB123940932. | |
| Eicosapentaenoic Acid Impurity11 | Eicosapentaenoic Acid Impurity11. Uses: For analytical and research use. CAS No. 2580285-53-4. Molecular formula: C20H32O2. Mole weight: 304.47. Catalog: APB2580285534. | |
| Eicosapentaenoic Acid Impurity12 | Eicosapentaenoic Acid Impurity12. Uses: For analytical and research use. Molecular formula: C22H42O2. Mole weight: 338.58. Catalog: APB12251. | |
| Eicosapentaenoic Acid Impurity13 | Eicosapentaenoic Acid Impurity13. Uses: For analytical and research use. Molecular formula: C21H32O2. Mole weight: 316.49. Catalog: APB12253. | |
| Eicosapentaenoic Acid Impurity14 | Eicosapentaenoic Acid Impurity14. Uses: For analytical and research use. Molecular formula: C22H34O2. Mole weight: 330.51. Catalog: APB12254. | |
| Eicosapentaenoic Acid Impurity15 | Eicosapentaenoic Acid Impurity15. Uses: For analytical and research use. Molecular formula: C88H136O8. Mole weight: 331.51. Catalog: APB12252. | |
| Eicosapentaenoic Acid Impurity16 | Eicosapentaenoic Acid Impurity16. Uses: For analytical and research use. CAS No. 2447131-67-9. Molecular formula: C22H32O2. Mole weight: 328.5. Catalog: APB2447131679. | |
| Eicosapentaenoic Acid Impurity2 | Eicosapentaenoic Acid Impurity2. Uses: For analytical and research use. CAS No. 125827-50-1. Molecular formula: C22H34O2. Mole weight: 330.51. Catalog: APB125827501. | |
| Eicosapentaenoic Acid Impurity3 | Eicosapentaenoic Acid Impurity3. Uses: For analytical and research use. CAS No. 173936-49-7. Molecular formula: C20H30O2. Mole weight: 302.46. Catalog: APB173936497. | |
| Eicosapentaenoic Acid Impurity4 | Eicosapentaenoic Acid Impurity4. Uses: For analytical and research use. CAS No. 125827-48-7. Molecular formula: C22H34O2. Mole weight: 330.51. Catalog: APB125827487. | |
| Eicosapentaenoic Acid Impurity5 | Eicosapentaenoic Acid Impurity5. Uses: For analytical and research use. CAS No. 140670-40-2. Molecular formula: C25H38O4. Mole weight: 402.58. Catalog: APB140670402. | |
| Eicosapentaenoic Acid Impurity6 | Eicosapentaenoic Acid Impurity6. Uses: For analytical and research use. CAS No. 124538-05-2. Molecular formula: C47H68O5. Mole weight: 713.06. Catalog: APB124538052. | |
| Eicosapentaenoic Acid Impurity7 | Eicosapentaenoic Acid Impurity7. Uses: For analytical and research use. CAS No. 2692622-82-3. Molecular formula: C21H32O2. Mole weight: 316.49. Catalog: APB2692622823. | |
| Eicosapentaenoic Acid Impurity8 | Eicosapentaenoic Acid Impurity8. Uses: For analytical and research use. Molecular formula: C21H32O2. Mole weight: 316.49. Catalog: APB12250. | |
| Eicosapentaenoic Acid Impurity9 | Eicosapentaenoic Acid Impurity9. Uses: For analytical and research use. Molecular formula: C22H34O2. Mole weight: 330.51. Catalog: APB12249. | |
| Eicosapentaenoic Acid (Standard) | Eicosapentaenoic Acid (Standard) is the analytical standard of Eicosapentaenoic Acid. This product is intended for research and analytical applications. Eicosapentaenoic Acid (EPA) is an orally active Omega-3 long-chain polyunsaturated fatty acid (ω-3 LC-PUFA). Eicosapentaenoic Acid exhibits a DNA demethylating action that promotes the re-expression of the tumor suppressor gene CCAAT/enhancer-binding protein δ (C/EBPδ). Eicosapentaenoic Acid activates RAS/ERK/C/EBPβ pathway through H-Ras intron 1 CpG island demethylation in U937 leukemia cells. Eicosapentaenoic Acid can promote relaxation of vascular smooth muscle cells and vasodilation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: EPA (Standard); Timnodonic acid (Standard). CAS No. 10417-94-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0660R. | |
| Eicosatetraynoic acid | ETYA is a nonspecific and cell permeable inhibitor of cyclooxygenases and lipoxygenases. ETYA inhibits phospholipase A2 (PLA2), cytochrome P-450, cyclooxygenase, 5-lipoxygenase, 12-lipoxygenase, and 15-lipoxygenase in whole cells. Synonyms: ETYA; 5,8,11,14-eicosatetraynoic acid; 1191-85-1; Eicosatetraynoic acid; icosa-5,8,11,14-tetraynoic acid; eicosatetranoic acid; Ro 3-1428; Octadehydroarachidonic acid; 5FEJ8J06DR; MLS000069514; MFCD00036967; SMR000058640; MLS-0002886.0001; Ro 31428; ITY; Opera_ID_402; Spectrum5_001952; UNII-5FEJ8J06DR; cid_1780; CBiol_001864; SCHEMBL68751; BSPBio_001449; KBioGR_000169; KBioSS_000169; BML2-F04; CHE. Grade: ≥98%. CAS No. 1191-85-1. Molecular formula: C20H24O2. Mole weight: 296.40. |  |
| Eicosyltriethyl Ammonium bromide | Eicosyltriethyl Ammonium bromide. Group: Biochemicals. Alternative Names: N,N,N-Triethyl-1-eicosanaminium bromide; n-Eicosyltriethyl Ammonium bromide. Grades: Highly Purified. CAS No. 75222-49-0. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C26H56BrN. US Biological Life Sciences. | Worldwide |
| EIDD-1931 | EIDD-1931 Inhibitor. Uses: Scientific use. Product Category: T8498. CAS No. 3258-2-4. |  |
| EIDD-1931 | EIDD-1931 (Beta-d-N4-hydroxycytidine; NHC) is a novel nucleoside analog and behaves as a potent anti-virus agent. EIDD-1931 effectively inhibits the replication activity of venezuelan equine encephalitis virus (VEEV), Chikungunya virus (CHIKV) and hepatitis C virus (HCV)[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: β-D-N4-hydroxycytidine; NHC. CAS No. 3258-2-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125033. | |
| EIDD-1931 | EIDD-1931 is a ribonucleoside analog that exhibits potential antiviral activity against SARS-CoV-2, MERS-CoV, SARS-CoV. EIDD-1931 induces mutations in RNA virions, inhibiting SARS-CoV-2 and other coronavirus in mice and human airway epithelial cells. Synonyms: N4-Hydroxycytidine; N(4)-Hydroxycytidine; Uridine, 4-oxime; Beta-D-N4-hydroxycytidine. Grade: 99.73%. CAS No. 3258-2-4. Molecular formula: C9H13N3O6. Mole weight: 259.22. | |
| EIDD-2749 | 4'-Fluorouridine is an orally active RdRp inhibitor. It effectively blocks the replication of RSV and SARS-CoV-2. Synonyms: 4'-fluorouridine; 1613589-24-4; 4'-C-Fluoro-uridine; 1-[(2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione; 1613591-91-5; SCHEMBL6839661; RDCYLPRXPILMRP-JVZYCSMKSA-N; AMY30709; EX-A6732; DA-70078; MS-23688; 4'-fluorouridine (4'-FlU, EIDD-2749)?; 1-((2R,3R,4S,5S)-5-fluoro-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. Grade: 98%. CAS No. 1613589-24-4. Molecular formula: C9H11FN2O6. Mole weight: 262.19. | |
| EIDD-2749 | EIDD-2749 (4'-Fluorouridine) is an orally active RdRp inhibitor. EIDD-2749 effectively blocks the replication of RSV and SARS-CoV-2. EIDD-2749 also exhibits activity against HCV and lymphocytic choriomeningitis virus (LCMV). EIDD-2749 is a promising oral therapeutic candidate for COVID-19 and is also suitable for research on other RNA viruses[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: 4'-FlU; 4'-Fluorouridine. CAS No. 1613589-24-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146246. | |
| EIDD-2801 | EIDD-2801, derived from N4-hydroxycytidine, is an oral bioavailable broad-spectrum antiviral compound that is effective against SARS-CoV2 infection. Uses: Antiviral agents. Synonyms: Molnupiravir; EIDD 2801; EIDD2801; MK-4482; WHO 11853; N4-Hydroxycytidine, 5'-isopropyl ester; beta-D-N4 Hydroxycytidine-5'-isopropyl ester; Uridine, 4-oxime, 5'-(2-methylpropanoate), (4Z)-; EIDD 1931-isopropyl ester; Lagevrio; MK-4482; β-D-N4 hydroxycytidine-5'-isopropyl ester. Grade: 95%. CAS No. 2492423-29-5. Molecular formula: C13H19N3O7. Mole weight: 329.31. | |
| eIF2α Antibody [C14N24] | EIF2S1,eIF2α. Group: Antibodies. Alternative Names: EIF2S1,eIF2α. Pack Sizes: 20ul. Product ID: F0316. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. |  United States; Europe |
| eIF4A3-IN-1 | eIF4A3-IN-1 is a selective eukaryotic initiation factor 4A3 (eIF4A3) inhibitor. It binds to a non-ATP binding site of eIF4A3 and shows significant cellular nonsense-mediated RNA decay (NMD) inhibition at 10 and 3 μM and can be as a probe for further study of eIF4A3, the exon junction complex (EJC), and NMD. Synonyms: eIF4A3-IN-1; 2095486-67-0; CHEMBL4073833; BDBM50265561; AKOS040733081; MS-30511; HY-101513; CS-0021616; 3-[4-[(3S)-4-(4-bromobenzoyl)-3-(4-chlorophenyl)piperazine-1-carbonyl]-5-methylpyrazol-1-yl]benzonitrile. Grade: 99%. CAS No. 2095486-67-0. Molecular formula: C29H23BrClN5O2. Mole weight: 588.88. | |
| eIF4A3-IN-1 | eIF4A3-IN-1 is a selective eIF4A3 inhibitor (IC50: 0.26 μM; Kd: 0.043 μM) with cellular nonsense-mediated RNA decay (NMD) inhibitory activity. eIF4A3-IN-1 can specifically bind to the non-ATP binding site of eIF4A3. eIF4A3-IN-1 has anti-tumor and analgesic activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095486-67-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101513. | |
| eIF4A3-IN-18 | eIF4A3-IN-18 (compound 74) is a Silvestrol (HY-13251) analogue. eIF4A3-IN-18 interferes the assembling of eIF4F translation complex with EC50 values of 0.8, 35 and 2 nM for myc-LUC, tub-LUC and the growth inhibition for MBA-MB-231 cells. eIF4A3-IN-18 also has cytotoxicity to RMPI-8226 cells with an LC50 of 0.06 nM. eIF4A3-IN-18 can be used for the research of human cancer pathogenesis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1402931-84-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-148452. | |
| eIF4A3-IN-2 | eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 (eIF4A3) inhibitor with an IC50 of 110 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095677-20-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-101785. | |
| eIF4A3-IN-2 | eIF4A3-IN-2 is a highly selective and noncompetitive eukaryotic initiation factor 4A-3 inhibitor with an IC50 of 110 nM. Synonyms: eIF4A3 inhibitor, 2. Grade: 99%. CAS No. 2095677-20-4. Molecular formula: C25H19Br2ClN4O2. Mole weight: 602.71. | |
| eIF4A3-IN-4 | eIF4A3-IN-4 is an inhibitor of eukaryotic initiation factor 4A (eIF4A) with an IC50 of 8.6 μM. Synonyms: eIF4A3-IN-4; CS-0256185. Molecular formula: C24H20N2O5. Mole weight: 416.43. | |
| eIF4A3-IN-5 | eIF4A3-IN-5, a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII, has the potential to study eIF4A dependent diseases, including cancer. (Extracted from patent US20170145026A1). Synonyms: 6H-Cyclopenta[4,5]furo[3,2-c]pyridine-7-carboxylic acid, 5a-(4-cyanophenyl)-5a,7,8,8a-tetrahydro-8,8a-dihydroxy-1,3-dimethoxy-6-phenyl-, (5aR,6S,7R,8R,8aS)-. CAS No. 2100145-31-9. Molecular formula: C26H22N2O7. Mole weight: 474.46. | |
| eIF4A3-IN-6 | eIF4A3-IN-6, a potent inhibitor of eukaryotic initiation factor 4A (eIF4A), such as eIF4AI and eIF4AII, has the potential to study eIF4A dependent diseases, including cancer. (Extracted from patent US20170145026A1). Synonyms: Benzonitrile, 4-[(5aR,6S,7S,8R,8aS)-7-(aminomethyl)-6,7,8,8a-tetrahydro-8,8a-dihydroxy-1,3-dimethoxy-6-phenyl-5aH-cyclopenta[4,5]furo[3,2-c]pyridin-5a-yl]-. CAS No. 2100133-77-3. Molecular formula: C26H25N3O5. Mole weight: 459.49. | |
| eIF4A3-IN-7 | eIF4A3-IN-7 is an effective inhibitor of eIF4A3, which has the potential to study cancer and other dysproliferative diseases. (extracted from patent WO2019161345A1, Compound 8). Synonyms: 1H-Cyclopenta[b]benzofuran-2-carboxamide, 2,3,3a,8b-tetrahydro-1,8b-dihydroxy-3a-(4-hydroxyphenyl)-6,8-dimethoxy-3-phenyl-, (1R,2R,3S,3aR,8bS)-. CAS No. 2374759-82-5. Molecular formula: C26H25NO7. Mole weight: 463.48. | |
| eIF4E-IN-1 | eIF4E-IN-1, a potent eIF4E inhibitor, inhibits immunosuppression components such as the immune checkpoint proteins PD-1, PD-L1, LAG3, TIM3, and/or IDO, in order to inhibit or release immunosuppression in certain diseases, such as cancer and infectious diseases. (Extracted from patent WO2021003194A1, compound Y). Synonyms: Thieno[3,2-b]pyridine-3-carboxylic acid, 7-[5-chloro-2-[2-[5-cyano-2-methyl-6-(4-methyl-1-piperazinyl)-4-oxo-7-(trifluoromethyl)-3(4H)-quinazolinyl]ethoxy]phenyl]-5-methyl-. CAS No. 2573979-31-2. Molecular formula: C33H28ClF3N6O4S. Mole weight: 697.13. | |
| eIF4E-IN-2 | eIF4E-IN-2, a potent inhibitor of eukaryotic initiation factor 4e (eIF4e), has the potential to study eIF4e-dependent diseases, including cancer. (Extracted from patent WO2021003157A1, compound 1188). Synonyms: 7-(5-chloro-2-(3-(5-cyano-6-((1-(3,3-difluorocyclobutyl)piperidin-4-yl)(methyl)amino)-2-methyl-4-oxopyrido[3,4-d]pyrimidin-3(4H)-yl)prop-1-yn-1-yl)phenyl)-N-(methylsulfonyl)thieno[3,2-b]pyridine-3-carboxamide. CAS No. 2575840-38-7. Molecular formula: C37H33ClF2N8O4S2. Mole weight: 791.29. | |
| eIF4E-IN-2 | eIF4E-IN-2 is a potent inhibitor of eukaryotic initiation factor 4e (eIF4e) with an IC50 of 13 nM. eIF4E-IN-2 inhibits MDA-MB-361 cells proliferation. eIF4E-IN-2 can be used for the study of breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2575840-38-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-145262. | |
| eIF4E-IN-3 | eIF4E-IN-3, a potent inhibitor of eukaryotic initiation factor 4e (eIF4e), has the potential to study eIF4e-dependent diseases, including cancer. (Extracted from patent WO2021003157A1, compound 485). Synonyms: Thieno[3,2-b]pyridine-3-carboxylic acid, 7-[5-chloro-2-[2-[5-cyano-2-methyl-6-[(4-methyl-1-piperazinyl)methyl]-4-oxo-7-(trifluoromethyl)-3(4H)-quinazolinyl]ethoxy]phenyl]-5-methyl-. CAS No. 2573979-29-8. Molecular formula: C34H30ClF3N6O4S. Mole weight: 711.15. | |
| EIPA | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Uses: Epithelial sodium channel blockers. Synonyms: Ethylisopropylamiloride; L 593754; MH 12-43; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide. Grade: ≥98% by HPLC. CAS No. 1154-25-2. Molecular formula: C11H18ClN7O. Mole weight: 299.76. | |
| EIPA | EIPA (L593754) is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA also enhances autophagy by inhibiting Na+/H+-exchanger 3 (NHE3). EIPA inhibits macropinocytosis as well. EIPA can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma[1][2][3][4][5][6][7]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L593754; MH 12-43; Ethylisopropylamiloride. CAS No. 1154-25-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840. | |
| EIPA hydrochloride | EIPA is a TRPP3 channel inhibitor (IC50 = 10.5 μM). EIPA also acts as an Na+/H+ exchange inhibitor that suppresses the Na+/H+ exchanger (NHE). Synonyms: L593754 hydrochloride; L 593754 hydrochloride; L-593754 hydrochloride; Ethylisopropylamiloride hydrochloride; MH 12-43 hydrochloride; 3-Amino-N-(aminoiminomethyl)-6-chloro-5-[ethyl(1-methylethyl)amino]-2-pyrazinecarboxamide hydrochloride. CAS No. 1345839-28-2. Molecular formula: C11H19Cl2N7O. Mole weight: 336.22. | |
| EIPA hydrochloride | EIPA (L593754) hydrochloride is an orally active TRPP3 channel inhibitor with an IC50 of 10.5 μM. EIPA hydrochloride also enhances autophagy by inhibiting Na+/H+-exchanger 3 (NHE3). EIPA hydrochloride inhibits macropinocytosis as well. EIPA hydrochloride can be used in the research of inflammation and cancers, such as gastric cancer, colon carcinoma, pancreatic carcinoma[1][2][3][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: L593754 hydrochloride; MH 12-43 hydrochloride; Ethylisopropylamiloride hydrochloride. CAS No. 1345839-28-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101840A. | |
| EIPA (L593754) | EIPA (L593754; MH 12-43) acts as an inhibitor of macropinocytosis and sodium-hydrogen exchangers(NHE) (IC50=0.033μg/mL). EIPA blocks the activity of Na(+)/H(+) exchanger, which are plasma membrane proteins implicated in all forms of macropinocytosis. Group: Inhibitors. Alternative Names: L593754; MH 12-43. CAS No. 1154-25-2. Pack Sizes: 5mg. Product ID: S9849. Formula: C11H18ClN7O. Smiles: CCN(C(C)C)C1=C(Cl)N=C(C(=N1)N)C(=O)NC(N)=N. Storage Conditions: 3 years -20°C powder. | United States; Europe |
| E-isomer Cefmenoxime impurity | E-isomer Cefmenoxime impurity. Uses: For analytical and research use. Alternative Names: (6R,7R)-7-((E)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid. Molecular formula: C16H17N9O5S3. Mole weight: 511.56. Catalog: APB04428. | |
| EIT hydrobromide | EIT hydrobromide is a potent and reversible inhibitor of isoform II NO synthase (IC50 = 13 nM; approximately 20- and 30-fold selective over isoforms I and III respectively). Uses: Enzyme inhibitors. Synonyms: (S)-Ethylisothiourea hydrobromide; 2-Ethyl-2-thiopseudourea hydrobromide; Ethiron bromide. CAS No. 1071-37-0. Molecular formula: C3H8N2S.HBr. Mole weight: 185.08. | |
| EIT hydrobromide | EIT hydrobromide. Group: Biochemicals. Grades: Purified. CAS No. 1071-37-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| Ekatetrone | It is produced by the strain of Streptomyces aureofaciens. It can inhibit the protein and nucleic acid synthesis of Ehrlician ascites cancer cells, and has no anti-bacterial and anti-yeast effect. Synonyms: (+)-2-(10,12-dihydroxy-3,6,11-trioxo-3,4,6,11-tetrahydro-1H-naphtho[2,3-g]isochromen-1-yl)acetamide; 1,8-Dihydroxy-2-(1'-hydroxy-2'-carbamoyl)ethyl-9,10-anthraquinone 3-acetic acid lactone; (+)-Ekatetrone; (+)-3,4,6,11-Tetrahydro-10,12-dihydroxy-3,6,11-trioxo-1H-anthra[2,3-c]pyran-1-acetamide. CAS No. 12794-19-3. Molecular formula: C19H13NO7. Mole weight: 367.31. | |
| EL-102 | EL102, a HIF1α inhibitor, has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. IC50: 20-40 nM. Uses: El102 is a hif1α inhibitor that has been found to have potential effect in restraining polymerisation of tubulin and influencing the stability of microtubule. Synonyms: EL 102; EL102. Grade: 95%. CAS No. 1233948-61-2. Molecular formula: C19H16N2O3S2. Mole weight: 384.47. | |
| ELA-11 (human) | ELA-11 (human) is a high affinity apelin receptor agonist (Ki = 14 nM). It is a bioactive fragment of ELA-32. ELA-11 (human) inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro. Synonyms: Elabela/Toddler-11; 1784687-32-6; ELA-11; GTPL8526; CHEMBL3809035; BDBM50172365. Grade: ≥95%. CAS No. 1784687-32-6. Molecular formula: C58H90N16O13S2. Mole weight: 1283.57. | |
| ELA-11 (human) acetate | ELA-11 (human) is a high affinity apelin receptor agonist (Ki = 14 nM). It is a bioactive fragment of ELA-32. ELA-11 (human) acetate inhibits forskolin-induced cAMP production and stimulates β-arrestin recruitment in vitro. Molecular formula: C60H94N16O15S2. Mole weight: 1343.61. | |
| ELA-14 (human) | ELA-14 (human) is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: Elabela (19-32). CAS No. 1886973-05-2. Molecular formula: C75H119N25O17S2. Mole weight: 1707.03. | |
| ELA-14 (human) acetate | ELA-14 (human) acetate is a potent apelin (APJ) receptor agonist (Ki = 0.93 nM) stimulating the Gαi1 pathway and β-arrestin-2 recruitment. It decreases arterial pressure in rat hearts. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro-OH.CH3CO2H; L-pyroglutamyl-L-arginyl-L-arginyl-L-cysteinyl-L-methionyl-L-prolyl-L-leucyl-L-histidyl-L-seryl-L-arginyl-L-valyl-L-prolyl-L-phenylalanyl-L-proline acetate; Elabela (19-32) acetate; ELA (19-32) (human) acetate. Grade: ≥95%. Molecular formula: C77H123N25O19S2. Mole weight: 1767.09. | |
| ELA-14 negative control | Negative control for ELA-14. Synonyms: H-Pyr-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Ala-Val-Pro-Phe-Pro-OH. CAS No. 1885873-44-8. Molecular formula: C72H112N22O17S2. Mole weight: 1621.93. | |
| ELA-21 (human) | ELA-21 (human) is a high affinity apelin receptor agonist that binds apelin receptors in left ventricle from normal and pulmonary arterial hypertensive (PAH) hearts (pKi values are 9.31 and 9.46, respectively). It is a bioactive fragment of ELA-32. Grade: ≥98%. Molecular formula: C112H184N40O25S3. Mole weight: 2587.12. | |
| ELA-21 (human) | ELA-21 (human) is an apelin receptor agonist with a pKi of 8.52. ELA-21 (human) completely inhibits Forskolin-induced cAMP production and stimulates β-arrestin recruitment with subnanomolar potencies. ELA-21 (human) is an agonist in G-protein-dependent and -independent pathways[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2245073-05-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2249. | |
| ELA-32 (human) | ELA-32 (human) is a potent apelin receptor agonist (IC50 = 0.27 nM; Kd=0.51 nM) stimulating the PI3K/AKT pathway and promoting self-renewal of hESCs via cell-cycle progression and protein translation. It also potentiates the TGFβ pathway, priming hESCs toward the endoderm lineage. Synonyms: ELA-32 (human); ELA 32 (human); ELA32 (human). Grade: >98%. CAS No. 1680205-79-1. Molecular formula: C170H289N63O39S4. Mole weight: 3967.8. | |
| Elabela(19-32) | Elabela(19-32) is an active fragment of ELABELA (ELA) that binds to apelin receptor (APJ). Elabela(19-32) activates the Gαi1 and β-arrestin-2 signaling pathways with EC50s of 8.6 nM and 166 nM. Elabela(19-32) induces receptor internalization and reduces arterial pressure, exerts positive inotropic effects on the heart[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1886973-05-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2106. | |
| Elacestrant | Elacestrant, also referred to RAD1901, is a selective and orally available estrogen receptor (ERR) degrader (IC50= 48 and 870 nM for ERα and ERβ, respectively) and selective estrogen receptor modulator (SERM). Synonyms: RAD1901; RAD-1901; RAD 1901. CAS No. 722533-56-4. Molecular formula: C30H38N2O2. Mole weight: 458.65. | |
| Elacestrant | Elacestrant (RAD1901) is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant also can inhibit growth of ER+ breast cancer cell lines in vitro and in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAD1901. CAS No. 722533-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19822. | |
| Elacestrant dihydrochloride | Elacestrant (RAD1901) dihydrochloride is an orally available and selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. Elacestrant dihydrochloride also can inhibit growth of ER+ breast cancer cell lines in vitro and in vivo[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAD1901 dihydrochloride. CAS No. 1349723-93-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-19822A. | |
| Elacestrant dihydrochloride | Elacestrant dihydrochloride is an orally available selective estrogen receptor degrader (SERD) with IC50s of 48 and 870 nM for ERα and ERβ, respectively. It is also a selective estrogen receptor modulator (SERM), with potential antineoplastic and estrogen-like activities. Synonyms: RAD1901 dihydrochloride; (R)-6-(2-(ethyl(4-(2-(ethylamino)ethyl)benzyl)amino)-4-methoxyphenyl)-5,6,7,8-tetrahydronaphthalen-2-ol dihydrochloride; 2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6R)-, hydrochloride (1:2). Grade: 98%. CAS No. 1349723-93-8. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. | |
| Elacestrant S enantiomer | Elacestrant S enantiomer is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Synonyms: RAD1901 S enantiomer; 2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6S)-; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol. CAS No. 2309762-29-4. Molecular formula: C30H38N2O2. Mole weight: 458.63. | |
| Elacestrant S enantiomer dihydrochloride | Elacestrant S enantiomer dihydrochloride is a low activity enantiomer of Elacestrant, which is a selective and orally bioavailable small-molecule SERD (IC50s = 48 and 870 nM for ERα and ERβ, respectively). Synonyms: RAD1901 S enantiomer dihydrochloride; (6S)-6-[2-(Ethyl{4-[2-(ethylamino)ethyl]benzyl}amino)-4-methoxyphenyl]-5,6,7,8-tetrahydro-2-naphthalenol dihydrochloride; 2-Naphthalenol, 6-[2-[ethyl[[4-[2-(ethylamino)ethyl]phenyl]methyl]amino]-4-methoxyphenyl]-5,6,7,8-tetrahydro-, (6S)-, hydrochloride (1:2). Grade: ≥95%. CAS No. 2309762-30-7. Molecular formula: C30H40Cl2N2O2. Mole weight: 531.56. | |
| Elacridar | Elacridar. Alternative Names: N-[4-[2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-9,10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide. CAS No. 143664-11-3. Purity: 98%. Product ID: ACM143664113. Molecular formula: C34H33N3O5. Mole weight: 563.6. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| Elacridar | Elacridar hydrochloride (GF120918A) is a P-glycoprotein inhibitor, and has been used both in vitro and in vivo as a tool inhibitor of P-glycoprotein (Pgp) to investigate the role of transporters in the disposition of various test molecules. In vitro, GF120918A demonstrated high plasma protein binding across species, although a definitive protein binding evaluation was precluded by poor recovery, particularly in buffer and in mouse, rat, and dog plasma. GF120918A did not demonstrate potent inhibition of several human cytochrome P450 enzymes evaluated in vitro, with IC(50) values well above concentrations anticipated to be achieved in vivo. Together, these data confirm the utility of GF120918A as a tool P-glycoprotein inhibitor in preclinical species and offer additional guidance on preclinical dose regimens likely to produce P-glycoprotein-mediated effects. Synonyms: GF120918; GF-120918; GF 120918; GF-120918A; GF120918A; GF 120918A; GG 918; D03968. Elacridar hydrochloride. CAS No. 143664-11-3. Molecular formula: C34H33N3O5. Mole weight: 563.654. | |
| Elacridar | Elacridar. Group: Biochemicals. Alternative Names: N-[4-[2- (3, 4-Dihydro-6, 7-dimethoxy-2 (1H) -isoquinolinyl) ethyl]phenyl]-9, 10-dihydro-5-methoxy-9-oxo-4-acridinecarboxamide; GF 120918; GG 918. Grades: Highly Purified. CAS No. 143664-11-3. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C??H??N?O?, Molecular Weight: 563.64. US Biological Life Sciences. | Worldwide |
| Elacridar | Elacridar is an orally active P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar can be used to examine the influence of efflux transporters on agent distribution to brain and the research of cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GF120918; GW0918; GG918; GW120918. CAS No. 143664-11-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-50879. | |
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