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| Product | Description | |
|---|---|---|
| ELND006 | ELND006 is one of the newest molecules to be reported on regarding the testing of the β-amyloid hypothesis. ELND006 is a novel oral γ-secretase inhibitor. At the 2010 Alzheimer's Association International Conference on Alzheimer's Disease in which ELND006 was reported to have an in vitro IC50 = 0.34 nM against APP and IC50 = 5.3 nM versus Notch signaling. Synonyms: ELND006; ELND-006; ELND 006. (4R)-4-cyclopropyl-7,8-difluoro-5-[4-(trifluoromethyl)phenyl]sulfonyl-1,4-dihydropyrazolo[4,3-c]quinoline; UNII-7F5QGV49GL; ELND006; ELND-006; 959997-22-9; (R)-4-Cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo(4,3-c)quinoline; (R)-4-cyclopropyl-7,8-difluoro-5-(4-(trifluoromethyl)phenylsulfonyl)-4,5-dihydro-1H-pyrazolo[4,3-c]quinoline; 7F5QGV49GL; SCHEMBL486044; GTPL7337; CHEMBL2396778. CAS No. 1333990-84-3. Molecular formula: C20H14F5N3O2S. Mole weight: 455.07. |  |
| ELND007 | ELND007 is a γ-secretase inhibitor. Synonyms: ELND007; ELND-007; ELND 007. (R)-4-cyclopropyl-8-fluoro-5-((6-(trifluoromethyl)pyridin-3-yl)sulfonyl)-4,5-dihydro-2H-pyrazolo[4,3-c]quinoline; ELND007; ELND-007; ELND 007. CAS No. 1444006-79-4. Molecular formula: C19H14F4N4O2S. Mole weight: 438.08. | |
| Elobixibat | Elobixibat is a potent and selective IBAT inhibitor under development for the treatment of chronic constipation and irritable bowel syndrome with constipation. Uses: Sodium-bile acid cotransporter-inhibitor. Synonyms: AZD-7806; AZD 7806; AZD7806; A 3309; A3309; A-3309; AJG-533; (2R)-N-[2-[[3,3-Dibutyl-2,3,4,5-tetrahydro-7-(methylthio)-1,1-dioxido-5-phenyl-1,5-benzothiazepin-8-yl]oxy]acetyl]-2-phenylglycylglycine. Grades: ≥95%. CAS No. 439087-18-0. Molecular formula: C36H45N3O7S2. Mole weight: 695.89. | |
| Elobixibat | Elobixibat (A 3309; AZD 7806) is an orally effective Apical Sodium-Dependent Bile (IBAT) inhibitor, with an IC 50 value of 0.53 nM (human IBAT ), 0.13 nM (mouse IBAT), 5.8 nM (canine IBAT). Elobixibat lowers LDL cholesterol, increases serum GLP-1, promotes colon motility, and has the potential to treat metabolic syndrome. Elobixibat can be used to study constipation, dyslipidemia, non-alcoholic hepatitis, and liver tumors [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 3309; AZD 7806. CAS No. 439087-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15790. |  |
| Elobixibat hydrate | Elobixibat hydrate is a potent ileal bile acid transporter (IBAT) inhibitor, with IC 50 values of 0.53 ± 0.17 nM, 0.13 ± 0.03 nM, and 5.8 ± 1.6 nM for human IBAT, mouse IBAT, and canine IBAT. Elobixibat hydrate can be used for chronic idiopathic constipation (CIC) research [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: A 3309 hydrate; AZD 7806 hydrate. CAS No. 1633824-78-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15790A. | |
| Elomotecan | Elomotecan (BN-80927) belongs to a novel family of camptothecin analogs, the homocamptothecins, developed on the concept of topoisomerase I (Topo I) inhibition and characterized by a stable seven-membered beta-hydroxylactone ring. Preclinical data reported here show that BN80927 retains Topo I poisoning activity in cell-free assay (DNA relaxation) as well as in living cells, in which in vivo complexes of topoisomerase experiments and quantification of DNA-protein-complexes stabilization, have confirmed the higher potency of BN80927 as compared with the Topo I inhibitor SN38. In addition, BN80927 inhibits Topo II-mediated DNA relaxation in vitro but without cleavable-complex stabilizatio...th assays, BN80927 is a very potent antiproliferative agent as shown by IC(50) values consistently lower than those of SN38 in tumor cell lines as well as in their related drug-resistant lines. BN80927 shows high efficiency in vivo in tumor xenograft studies using human androgen-independent prostate tumors PC3 and DU145. Altogether, these data strongly support the clinical development of BN80927. Synonyms: BN-80927; BN80927; BN 80927; R-1559; R1559; R 1559; (R)-9-chloro-5-ethyl-5-hydroxy-10-methyl-12-((4-methylpiperidin-1-yl)methyl)-4, 5-dihydrooxepino[3', 4':6, 7]indolizino[1, 2-b]quinoline-3, 15(1H, 13H)-dione. CAS No. 220998-10-7. Molecular formula: C29H32ClN3O4. Mole weight: 522.04. | |
| Elomotecan HCl salt | Elomotecan, also referred to BN 80927 and R 1559, characterized by a stable seven-membered beta-hydroxylactone ring, is a DNA topoisomerase inhibitor. In vivo elomotecan shows high efficiency in vivo in tumor xenograft studies using human androgen-independent prostate tumors PC3 and DU145. Synonyms: 220997-99-9; 220998-10-7 (Elomotecan free base); (5R)-9-chloro-5-ethyl-5-hydroxy-10-methyl-12-[(4-methylpiperidin-1-yl)methyl]-1,4,5,13-tetrahydro-3H,15H-oxepino[3',4':6,7]indolizino[1,2-b]quinoline-3,15-dione hydrochloride (1:1). Grades: >98%. CAS No. 220997-99-9. Molecular formula: C29H33Cl2N3O4. Mole weight: 558.5. | |
| elongation factor 2 kinase | Requires Ca2+ and calmodulin for activity. The enzyme can also be phosphorylated by the catalytic subunit of EC 2.7.11.11, cAMP-dependent protein kinase. Elongation factor 2 is phosphorylated in several cell types in response to various growth factors, hormones and other stimuli that raise intracellular Ca2+. Group: Enzymes. Synonyms: Ca/CaM-kinase III; calmodulin-dependent protein kinase III; CaM kinase III; eEF2 kinase; eEF2K; EF2K; STK19. Enzyme Commission Number: EC 2.7.11.20. CAS No. 116283-83-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3140; elongation factor 2 kinase; EC 2.7.11.20; 116283-83-1; Ca/CaM-kinase III; calmodulin-dependent protein kinase III; CaM kinase III; eEF2 kinase; eEF2K; EF2K; STK19. Cat No: EXWM-3140. |  |
| Elotuzumab | Elotuzumab is a monoclonal antibody directed against the SLAMF7 receptor. Elotuzumab has no significant antimyeloma activity when given as a single agent with relapsed or refractory multiple myeloma (RRMM). Elotuzumab results in improved response and outcome when combined with other antimyeloma agents [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: HuLuc 63; PDL 063; BMS 901608. CAS No. 915296-00-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P9965. | |
| ELOVL1-IN-2 | ELOVL1-IN-2 is an inhibitor of ELOVL1 (elongation of very-long-chain-fatty acid 1). CAS No. 2761063-79-8. Molecular formula: C18H15FN2O. Mole weight: 294.3. | |
| Elpetrigine | Elpetrigine, also known as GW 273293 and JZP-4, has a blocking effect on calcium channels and potassium channels which has been in clinical bipolar disorders and epilepsy. Synonyms: 3-(2,3,5-trichlorophenyl)pyrazine-2,6-diamine; GW273293; GW-273293; GW 273293; JZP-4; JZP 4; JZP4; Elpetrigine. Grades: >98%. CAS No. 212778-82-0. Molecular formula: C10H7Cl3N4. Mole weight: 289.54. | |
| Elphodex Acidic Kit | Elphodex Acidic Kit. Group: Polysaccharide. |  |
| Elphodextrin Starter Kit | Elphodextrin Starter Kit. Group: Polysaccharide. | |
| ELQ-300 | ELQ-300 is a potent and orally bioavailable antimalarial agent, and it is a novel inhibitor of the reductive (Qi) site of the cytochrome bc1 complex (complex III in the electron transport chain). Synonyms: 6-chloro-7-methoxy-2-methyl-3-[4-[4-(trifluoromethoxy)phenoxy]phenyl]-1H-quinolin-4-one. Grades: ≥98%. CAS No. 1354745-52-0. Molecular formula: C24H17ClF3NO4. Mole weight: 475.84. | |
| ELR510444 | ELR510444 is a potent microtube disruptor with potential anticancer activity. ELR510444 has potent microtubule-disrupting activity, causing a loss of cellular microtubules and the formation of aberrant mitotic spindles and leading to mitotic arrest and apoptosis of cancer cells. ELR510444 potently inhibited cell proliferation with an IC(50) value of 30.9 nM in MDA-MB-231 cells, inhibited the rate and extent of purified tubulin assembly, and displaced colchicine from tubulin, indicating that the drug directly interacts with tubulin at the colchicine-binding site. ELR510444 is not a substrate for the P-glycoprotein drug transporter and retains activity in βIII-tubulin-overexpressing cell lines, suggesting that it circumvents both clinically relevant mechanisms of drug resistance to this class of agents. ELR510444 also shows potent antitumor activity in the MDA-MB-231 xenograft model with at least a 2-fold therapeutic window. Synonyms: ELR510444; ELR-510444; ELR 510444. Grades: >98%. CAS No. 1233948-35-0. Molecular formula: C19H16N2O2S2. Mole weight: 368.47. | |
| Elranatamab | Elranatamab (PF-06863135) is an anti- CD3E/TNFRSF17 human IgG2κ monoclonal antibody [1]. Recommend Isotype Controls: Human IgG2 kappa, Isotype Control (HY-P99002). Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PF-06863135. CAS No. 2408850-14-4. Pack Sizes: 1 mg; 5 mg. Product ID: HY-P99909. | |
| Elsamicin B | Elsamicin B is produced by the strain of Actinomycetes J904-21. It is an antitumor antibiotic in the Chartreusin group. Aminoglycogen-deficient Elsamicin B shows only minimal antitumor activity. Synonyms: 10-[(3-C-Methyl-6-deoxy-β-D-galactopyranosyl)oxy]-6-hydroxy-1-methylbenzo[h][1]benzopyrano[5,4,3-cde][1]benzopyran-5,12-dione; Benzo(h)(1)benzopyrano(5,4,3-cde)(1)benzopyran-5,12-dione, 10-((6-deoxy-3-C-methyl-beta-D-galactopyranosyl)oxy)-6-hydroxy-1-methyl-; 6-Hydroxy-1-methyl-5,12-dioxo-5,12-dihydrobenzo[g][2]benzopyrano[5,4,3-cde][2]benzopyran-10-yl 6-deoxy-3-C-methylhexopyranoside. CAS No. 97068-31-0. Molecular formula: C26H22O10. Mole weight: 494.45. | |
| Elsamitrucin | Elsamitrucin is produced by the strain of Actinomycetes J904-21. It has strong anti-tumor activity of mouse tumor cells such as leukemia P388, L1210 and melanoma B16, and its anti-tumor activity is 10-30 times stronger than Chartreusin. Uses: Antibiotics, antineoplastic. Synonyms: Elsamicin A. Grades: >95%. CAS No. 97068-30-9. Molecular formula: C33H35NO13. Mole weight: 653.63. | |
| Elsibucol | Elsibucol, a metabolically stable derivative of probucol, inhibits atherosclerosis and preserves endothelial healing following arterial injury. In vitro, elsibucol reduces vascular smooth muscle cell proliferation without affecting cell viability. Synonyms: 4-[2,6-ditert-butyl-4-[2-(3,5-ditert-butyl-4-hydroxyphenyl)sulfanylpropan-2-ylsulfanyl]phenoxy]butanoic acid; (4,2,6-di-tert-butyl-4-(1-(3,5-di-tert-butyl-4-hydroxy-phenylsulfanyl)-1-methyl-ethylsulfanyl)-phenoxy-butyric acid); Elsibucol; AGI 1096; AGI1096; AGI-1096; Elsibucol; UNII-O7T92N1Y8T.elsibucol. Grades: >98%. CAS No. 216167-95-2. Molecular formula: C35H54O4S2. Mole weight: 602.94. | |
| Elsilimomab | Elsilimomab (B-E8) is a IgG1 monoclonal antibody against interleukin-6 (IL-6) , with a K D of 22 pM and an IC 50 of 1.4 nM. Elsilimomab can be used for the research of multiple myeloma, renal cell carcinoma, and rheumatoid arthritis (RA) [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: B-E8; Anti-IL-6 MAB B-E8; Anti-Human IL6 Recombinant Antibody. CAS No. 468715-71-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99287. | |
| Elsinochrome A | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: (1r,2r)-1,2-diacetyl-4,11-dihydroxy-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-5,10-dione; 1alpha,2beta-Diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxybenzo[ghi]perylene-4,11-dione; Benzo(ghi)perylene-4,11-dione, 1,2-diacetyl-1,2-dihydro-5,10-dihydroxy-3,7,8,12-tetramethoxy-, trans-. Grades: ≥98%. CAS No. 24568-67-0. Molecular formula: C30H24O10. Mole weight: 544.51. | |
| Elsinochrome B | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 1-Acetyl-5,10-dihydroxy-2-(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione. Grades: ≥98%. CAS No. 24512-58-1. Molecular formula: C30H26O10. Mole weight: 546.52. | |
| Elsinochrome C | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 5,10-Dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-1,2-dihydrobenzo[ghi]perylene-4,11-dione; Benzo[ghi]perylene-4,11-dione,1,2-dihydro-5,10-dihydroxy-1,2-bis(1-hydroxyethyl)-3,7,8,12-tetramethoxy-. Grades: ≥98%. CAS No. 24512-87-6. Molecular formula: C30H28O10. Mole weight: 548.54. | |
| Elsinochrome D | It is produced by the strain of Elsinoe annonae, Sphaceloma randii. It's the same as Hypericin, it has photodynamic activity and inhibits protein kinase C activity. Synonyms: 12,13-Dihydro-2-hydroxy-12,13-bis(1-hydroxyethyl)-1,5,6-trimethoxybenzo[1,12]perylo[2,3-d][1,3]dioxole-3,8-dione. Grades: ≥98%. CAS No. 32500-05-3. Molecular formula: C30H26O10. Mole weight: 546.52. | |
| Elsulfavirine | Elsulfavirine is a reverse transcriptase inhibitors for HIV-1 infection and is a new anti-HIV agent [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: R-1206. CAS No. 868046-19-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-109056. | |
| Elsulfavirine | Elsulfavirine is a new-generation non-nucleoside reverse transcriptase inhibitor (NNRTI) being developed by Viriom for the treatment and prevention of human immunodeficiency virus (HIV) infections. It is the prodrug of the active compound VM-1500A, a small molecule selective NNRTI, which prevents HIV replication. In June 2017, elsulfavirine received its first global approval in Russia for the treatment of HIV-1 infections in combination with other antiretroviral medicines. Other formulations of this drug are also being evaluated in preclinical and phase II studies for the treatment of HIV infections and/or pre-exposure and post-exposure prophylaxis. Group: Inhibitors. Alternative Names: Elsulfavirine; Elpida. CAS No. 868046-19-9. Molecular formula: C24H17BrCl2FN3O5S. Mole weight: 629.28. Appearance: Solid powder. Purity: >98%. IUPACName: N-(4-{2-[4-bromo-3-(3-chloro-5-cyanophenoxy)-2-fluorophenyl]acetamido}-3-chlorobenzenesulfonyl)propanamide. Canonical SMILES: CCC (NS (=O) (C1=CC=C (NC (CC2=CC=C (Br)C (OC3=CC (C#N)=CC (Cl)=C3)=C2F)=O)C (Cl)=C1)=O)=O. Catalog: ACM868046199. |  |
| Eltanexor | Eltanexor (KPT-8602) is an investigational second-generation SINE compound. Eltanexor acts as an orally bioavailable XPO1 (also known as CRM1) inhibitor with IC50 values of 20-211?nM in 10 AML lines after 3 days exposure. Synonyms: KPT-8602; ONO-7706; ATG-016. Grades: ≥98%. CAS No. 1642300-52-4. Molecular formula: C17H10F6N6O. Mole weight: 428.29. | |
| Eltanexor | Eltanexor (KPT-8602) is a second-generation, highly specific and orally active exportin-1 (XPO1) inhibitor with potent anti-leukemic activity. Eltanexor (KPT-8602) inhibits XPO1-dependent nuclear export ( EC 50 =60.9 nM) by directly targeting XPO1. Eltanexor (KPT-8602) induces Caspase-dependent apoptosis in a panel of leukemic cell lines [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KPT-8602. CAS No. 1642300-52-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100423. | |
| Eltenac | A nonsteroidal anti-inflammatory drug. Group: Biochemicals. Alternative Names: 4-[(2,6-Dichlorophenyl)amino]-3-thiopheneacetic Acid; 4-(2,6-Dichloroanilino)-3-thiopheneacetic Acid; Telzenac; [4- (2, 6-Dichlorophenylamino) thiophen-3-yl]acetic Acid. Grades: Highly Purified. CAS No. 72895-88-6. Pack Sizes: 2.5mg. US Biological Life Sciences. |  Worldwide |
| Eltenac-13C,d3 | Labeled Eltenac. A nonsteroidal anti-inflammatory drug. Group: Biochemicals. Alternative Names: 4-[(2,6-Dichlorophenyl)amino]-3-thiopheneacetic Acid-13C,d3; 4-(2,6-Dichloroanilino)-3-thiopheneacetic Acid-13C,d3; Telzenac-13C,d3; [4- (2, 6-Dichlorophenylamino) thiophen-3-yl]acetic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Eltoprazine | Eltoprazine belongs the phenylpiperazine class which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor with Ki values of 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively. It is closely related to fluprazine and batoprazine, which are similarly acting drugs. It has been shown to reduce L-DOPA-induced dyskinesias in experimental models of Parkinson's Disease and in human patients, although this effect was accompanied by a partial worsening of the therapeutic effect of l-dopa in vivo. It was found to (synergistically) potentiate the antidyskinetic effect of amantadine. It has been shown to reduce 5-HIAA levels in the striatum and exhibits antiaggressive behavior in vivo. It is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. It was developed by PsychoGenics and Amarantus Bioscience, Inc. It is in clinical stage 3. Uses: Eltoprazine has been shown to reduce l-dopa-induced dyskinesias in experimental models of parkinson's disease and in human patients. it is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. Synonyms: Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-;1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine;DU-28853;DU28853. Grades: >98 %. CAS No. 98224-03-4. Molecular formula: C12H16N2O2. Mole weight: 220.27. | |
| Eltoprazine hydrochloride | Eltoprazine (DU 28853) hydrochloride is a 5-HT1A/5-HT1B receptors agonist and a 5-HT2C receptor antagonist. Eltoprazine hydrochloride shows antiaggressive and anxiogenic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: DU 28853 hydrochloride. CAS No. 98206-09-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16687A. | |
| Eltoprazine hydrochloride | Eltoprazine hydrochloride is the hydrochloride form of Eltoprazine which is a serenic or antiaggressive agent. It acts as an agonist at the 5-HT1A and 5-HT1B receptors and as an antagonist at the 5-HT2C receptor with Ki values of 40, 52 and 81 nM for 5-HT1A, 5-HT1B and 5-HT2C receptors respectively. It has been shown to reduce L-DOPA-induced dyskinesias in experimental models of Parkinson's Disease and in human patients, although this effect was accompanied by a partial worsening of the therapeutic effect of l-dopa in vivo. It is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. It was developed by PsychoGenics and Amarantus Bioscience, Inc. It is in clinical stage 3. Uses: Eltoprazine hydrochloride has been shown to reduce l-dopa-induced dyskinesias in experimental models of parkinson's disease and in human patients. it is used as a novel drug for the treatment of anxiety as well as other neurological and mental disorders. Synonyms: Piperazine, 1-(2,3-dihydro-1,4-benzodioxin-5-yl)-, monohydrochloride;1-(2,3-dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride;DU-28853 hydrochloride;DU28853 hydrochloride. Grades: >98 %. CAS No. 98206-09-8. Molecular formula: C12H17N2O2Cl. Mole weight: 256.73. | |
| Eltoprazine hydrochloride | Eltoprazine hydrochloride. Group: Biochemicals. Alternative Names: 1-(2,3-Dihydro-1,4-benzodioxin-5-yl)piperazine hydrochloride; DU 28853; DU 28893. Grades: Highly Purified. CAS No. 98206-09-8. Pack Sizes: 25mg, 50mg, 100mg, 250mg, 500mg. Molecular Formula: C12H17ClN2O2. US Biological Life Sciences. | Worldwide |
| Eltrombopag | An agonist of the Thrombopoietin (Tpo) receptor, used as treatment for thrombocytopenia. Group: Biochemicals. Alternative Names: 3'-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid; SB 497115. Grades: Highly Purified. CAS No. 496775-61-2. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Eltrombopag | Eltrombopag is a member of the biarylhydrazone class, which is a nonpeptide agonist of the thrombopoietin receptor (TpoR). Uses: Nonpeptide thrombopoietin receptor agonist. Synonyms: SB-497115-GR, SB497115. Grades: >98%. CAS No. 496775-61-2. Molecular formula: C25H22N4O4. Mole weight: 442.47. | |
| Eltrombopag | Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: SB-497115. CAS No. 496775-61-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15306. | |
| Eltrombopag | Eltrombopag (SB-497115) is an orally active thrombopoietin receptor nonpeptide agonist. Eltrombopag owns thrombopoietic activity, and has been used to research low blood platelet counts with chronic immune thrombocytopenia. Eltrombopag can be used for the research of cardiovascular. Eltrombopag also has highly inhibitory effects against multidrug resistant Staphylococcus aureus. Eltrombopag can induce apoptosis in hepatocellular carcinomab (HCC) as well. Group: Inhibitors. Alternative Names: Eltrombopag;3-[2-[(2Z)-1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2-hydroxy-[1,1-biphenyl]-3-carboxylic acid;(1,1-Biphenyl)-3-carboxylic acid, 3-((2Z)-(1-(3,4-dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene)hydrazino)-2-hydroxy-;Eltrombopag [inn];Promacta;Sb497115;Sb-497115;Unii-S56D65xj9g. CAS No. 496775-61-2. Molecular formula: C25H22N4O4. Mole weight: 442.47. Appearance: Solid. Purity: 0.9973. Canonical SMILES: O=C (C1=CC (C2=CC=CC (N/N=C3C (C)=NN (C4=CC=C (C)C (C)=C4)C/3=O)=C2O)=CC=C1)O. Density: 1.33. Catalog: ACM496775612. | |
| Eltrombopag-13C4 | Eltrombopag- 13 C 4 (SB-497115- 13 C 4 ) is 13 sup>C-labeled Z-Eltrombopag. Z-Eltrombopag is an orally active thrombopoietin-receptor non-peptide agonist with platelet-stimulating activity for the study of chronic immune thrombocytopenia. Eltrombopag also has strong inhibitory effects on multidrug-resistant Staphylococcus aureus ( Staphylococcus aureus ) and can induce apoptosis ( apoptosis ) in liver cancer cells [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Isotope-labeled compounds. Alternative Names: SB-497115- 13 C4. CAS No. 1217230-31-3. Pack Sizes: 1 mg. Product ID: HY-15306S. | |
| Eltrombopag Acyl Glucuronide | | |
| Eltrombopag Amide | Eltrombopag Amide is a metabolite of Eltrombopag. Synonyms: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grades: > 95%. CAS No. 1246929-02-1. Molecular formula: C25H23N5O3. Mole weight: 441.48. | |
| Eltrombopag Amide | Eltrombopag Amide. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxamide. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C25H23N5O3, Molecular Weight: 441.48. US Biological Life Sciences. | Worldwide |
| Eltrombopag Ethyl Ester | Eltrombopag Ethyl Ester. Group: Biochemicals. Alternative Names: 3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene]hydrazinyl]-2'-hydroxy-[1,1'-Biphenyl]-3-carboxylic Acid Ethyl Ester. Grades: Highly Purified. Pack Sizes: 5mg. Molecular Formula: C27H26N4O4, Molecular Weight: 470.52. US Biological Life Sciences. | Worldwide |
| Eltrombopag Glucuronide | Eltrombopag Glucuronide. Group: Biochemicals. Alternative Names: 1-[3'-[(2Z)-2-[1-(3,4-Dimethylphenyl)-1,5-dihydro-3-methyl-5-oxo-4H-pyrazol-4-ylidene-3-14C]hydrazinyl]-2'-hydroxy[1,1'-biphenyl]-3-carboxylate]- β-D-glucopyranuronic Acid. Grades: Highly Purified. Pack Sizes: 2.5mg. Molecular Formula: C31H30N4O10, Molecular Weight: 618.59. US Biological Life Sciences. | Worldwide |
| Eltrombopag Impurity 1 | Eltrombopag Impurity 1. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (E)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)-1-hydroxyhydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid. Molecular Formula: C25H22N4O5. Mole Weight: 458.47. Catalog: APB05640. |  |
| Eltrombopag Impurity 14 | Eltrombopag Impurity 14. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1097777-60-0. Molecular Formula: C13H9NO5. Mole Weight: 259.22. Catalog: APB1097777600. | |
| Eltrombopag Impurity 2 | Eltrombopag Impurity 2. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5',5''-bis((Z)-2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-4'',6'-dihydroxy-[1,1':3',1'':3'',1'''-quaterphenyl]-3,3'''-dicarboxylic acid. Molecular Formula: C50H42N8O8. Mole Weight: 882.92. Catalog: APB05641. | |
| Eltrombopag Impurity 21 | Eltrombopag Impurity 21. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H22N4O5. Mole Weight: 458.47. Catalog: APB07756. | |
| Eltrombopag Impurity 22 | Eltrombopag Impurity 22. Uses: For analytical and research use. Group: Impurity standards. CAS No. 43192-07-0. Molecular Formula: C8H11NO. Mole Weight: 137.18. Catalog: APB43192070. | |
| Eltrombopag Impurity 23 | Eltrombopag Impurity 23. Uses: For analytical and research use. Group: Impurity standards. CAS No. 67666-03-9. Molecular Formula: C16H20N2. Mole Weight: 240.34. Catalog: APB67666039. | |
| Eltrombopag Impurity 24 | Eltrombopag Impurity 24. Uses: For analytical and research use. Group: Impurity standards. CAS No. 29418-36-8. Molecular Formula: C16H18N2. Mole Weight: 238.33. Catalog: APB29418368. | |
| Eltrombopag Impurity 25 | Eltrombopag Impurity 25. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H24N4O4. Mole Weight: 456.5. Catalog: APB07757. | |
| Eltrombopag Impurity 27 | Eltrombopag Impurity 27. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid. CAS No. 893736-72-6. Molecular Formula: C13H10O3. Mole Weight: 214.22. Catalog: APB893736726. | |
| Eltrombopag Impurity 29 | Eltrombopag Impurity 29. Uses: For analytical and research use. Group: Impurity standards. CAS No. 376592-57-3. Molecular Formula: C13H9ClO3. Mole Weight: 248.66. Catalog: APB376592573. | |
| Eltrombopag Impurity 3 | Eltrombopag Impurity 3. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-ethyl 3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate. Molecular Formula: C27H26N4O4. Mole Weight: 470.52. Catalog: APB05639. | |
| Eltrombopag Impurity 32 | Eltrombopag Impurity 32. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1782285-05-5. Molecular Formula: C12H14N2O. Mole Weight: 202.26. Catalog: APB1782285055. | |
| Eltrombopag Impurity 33 | Eltrombopag Impurity 33. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C13H10N2O4. Mole Weight: 258.23. Catalog: APB07758. | |
| Eltrombopag Impurity 34 | Eltrombopag Impurity 34. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C13H15N3O. Mole Weight: 229.28. Catalog: APB07759. | |
| Eltrombopag Impurity 35 | Eltrombopag Impurity 35. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C50H42N8O8. Mole Weight: 882.93. Catalog: APB07761. | |
| Eltrombopag Impurity 36 | Eltrombopag Impurity 36. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2734533-17-4. Molecular Formula: C25H22N4O5. Mole Weight: 458.47. Catalog: APB2734533174. | |
| Eltrombopag Impurity 37 | Eltrombopag Impurity 37. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 1-(3,4-dimethylphenyl)-4-ethyl-3-methyl-1H-pyrazol-5(4H)-one. CAS No. 350024-70-3. Molecular Formula: C14H18N2O. Mole Weight: 230.31. Catalog: APB350024703. | |
| Eltrombopag Impurity 37 | Eltrombopag Impurity 37. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C14H18N2O2. Mole Weight: 246.31. Catalog: APB07762. | |
| Eltrombopag Impurity 38 | Eltrombopag Impurity 38. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3'-amino-2'-((3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carbonyl)oxy)-[1,1'-biphenyl]-3-carboxylic acid. Molecular Formula: C26H20N2O5. Mole Weight: 440.45. Catalog: APB05614. | |
| Eltrombopag Impurity 39 | Eltrombopag Impurity 39. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 3'-(3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-ylcarboxamido)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid. Molecular Formula: C26H20N2O5. Mole Weight: 440.45. Catalog: APB05612. | |
| Eltrombopag Impurity 4 | Eltrombopag Impurity 4. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 5'-chloro-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid. Molecular Formula: C13H9ClO3. Mole Weight: 248.66. Catalog: APB05638. | |
| Eltrombopag Impurity 40 | Eltrombopag Impurity 40. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: ethyl 3'-amino-2'-hydroxy-[1,1'-biphenyl]-3-carboxylate. Molecular Formula: C15H15NO3. Mole Weight: 257.28. Catalog: APB05611. | |
| Eltrombopag Impurity 41 | Eltrombopag Impurity 41. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-5'-bromo-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)hydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid. Molecular Formula: C25H21BrN4O4. Mole Weight: 521.36. Catalog: APB05609. | |
| Eltrombopag Impurity 42 | Eltrombopag Impurity 42. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C36H42N6O3. Mole Weight: 606.77. Catalog: APB07769. | |
| Eltrombopag Impurity 43 | Eltrombopag Impurity 43. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C25H22N4O4. Mole Weight: 442.48. Catalog: APB07763. | |
| Eltrombopag Impurity 44 | Eltrombopag Impurity 44. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: (Z)-3'-(2-(1-(3,4-dimethylphenyl)-3-methyl-5-oxo-1H-pyrazol-4(5H)-ylidene)-1-hydroxyhydrazinyl)-2'-hydroxy-[1,1'-biphenyl]-3-carboxylic acid. Molecular Formula: C25H22N4O5. Mole Weight: 458.47. Catalog: APB05608. | |
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