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| Product | Description | |
|---|---|---|
| EGA | EGA is an inhibitor of endosomal trafficking. EGA is a small molecule that blocks the entry of anthrax lethal toxin by inhibiting trafficking pathways in acidified endosomes, without affecting endosome pH. It also blocks trafficking of other toxins, except ricin. Synonyms: 2-[(4-bromophenyl)methylene]-N-(2,6-dimethylphenyl)-hydrazinecarboxamide. Grades: ≥98%. CAS No. 415687-81-9. Molecular formula: C16H16BrN3O. Mole weight: 346.2. |  |
| EGA | EGA is an inhibitor that selectively targets the endosomal trafficking pathways. EGA targets the proteins involved in the endosomal trafficking pathways through which multiple toxins and viruses enter cells. EGA exerts its activity by inhibiting the trafficking from early endosomes to late endosomes, blocking the entry of multiple acid-dependent bacterial toxins and viruses into mammalian cells and delaying the lysosomal targeting and degradation of EGFR [1]. X. Uses: Scientific research. Group: Signaling pathways. CAS No. 415687-81-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-125168. |  |
| Egalognastat | Egalognastat is a specific and orally active O-GlcNAcase (OGA) enzyme inhibitor with IC 50 value of 10.2 nM. Egalognastat can be used for the research of neurodegenerative diseases, such as tauopathies and α-synucleinopathies [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: ASN90. CAS No. 1884154-02-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-156586. | |
| Eganelisib | Eganelisib (IPI549) is a potent and selective PI3Kγ inhibitor with an IC 50 of 16 nM. Eganelisib shows >100-fold selectivity over other lipid and protein kinases [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: IPI-549. CAS No. 1693758-51-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100716. | |
| EGCG-3''-O-Me | EGCG-3''-O-Me. Group: Biochemicals. Grades: Plant Grade. CAS No. 83104-87-4. Pack Sizes: 5mg. Molecular Formula: C23H20O11, Molecular Weight: 472.4. US Biological Life Sciences. |  Worldwide |
| EGCG Octaacetate | EGCG Octaacetate. Group: Biochemicals. Alternative Names: Pro-epigallocatechin gallate; Peracetylated epigallocatechin-3-gallate; Epigallocatechin Gallate Octaacetate; AcEGCG. Grades: Plant Grade. CAS No. 148707-39-5. Pack Sizes: 20mg. Molecular Formula: C38H34O19, Molecular Weight: 794.671. US Biological Life Sciences. | Worldwide |
| Ege I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA (HindIII-digest) in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme 70% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. GGC↑GCC CCG↓CGG. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer B, BSA. Storage: -20°C. Form: Liquid. Source: Enterobacter gergoviae. Pack: 10 mM Tris-HCl (pH 7.5); 250 mM NaCl; 0,1 mM EDTA; 7 mM 2-mercaptoethanol; 50% glycerol. Cat No: ET-1103RE. |  |
| EGF816 | EGF816, also called as Nazartinib, a covalent mutant-selective EGFR inhibitor and potently inhibits the T790M resistance mutation while sparing wild-type EGFR. in vivo: demonstrated strong tumor regressions in several EGFR activating and resistant tumor m. Synonyms: EGF816; EGF-816; EGF 816; NVS-816; NVS 816; NVS816; Nazartinib; N- [7-chloro -1- [ (3R) -1- [ (E) -4- (di methyl amino) but-2-enoyl ] azepan-3-yl ] benzimidazol-2-yl ] -2- methyl pyridine-4-carboxamide EGF816UNII-KE7K32EME8KE7K32EME8EGF-8161508250-71-2GTPL9204SCHEMBL16767232SCHEMBL16767 240EGF 816compound 47 [PMID: 27433829]. CAS No. 1508250-71-2. Molecular formula: C26H31ClN6O2. Mole weight: 495.02. | |
| EGF816 mesylate | EGF816 mesylate is the mesylate salt of EGF816 which is a covalent mutant-selective EGFR inhibitor and potently inhibits the T790M. Synonyms: N-[7-chloro-1-[(3R)-1-[(E)-4-(dimethylamino)but-2-enoyl]azepan-3-yl]benzimidazol-2-yl]-2-methylpyridine-4-carboxamide;methanesulfonic acid. CAS No. 1508250-72-3. Molecular formula: C27H35ClN6O5S. Mole weight: 591.12. | |
| EGF Receptor (985-996) (human) | EGF Receptor (985-996) (human) exists on the cell surface and is activated by the binding of its specific ligands. EGFR belongs to the tyrosine kinase receptor (RTK) ErbB family. Synonyms: L-Glutamine, L-α-aspartyl-L-valyl-L-valyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-tyrosyl-L-leucyl-L-isoleucyl-L-prolyl-; L-Glutamine, N2-[1-[N-[N-[N-[N-[N-[N-[N-[N-(N-L-α-aspartyl-L-valyl)-L-valyl]-L-α-aspartyl]-L-alanyl]-L-α-aspartyl]-L-α-glutamyl]-L-tyrosyl]-L-leucyl]-L-isoleucyl]-L-prolyl]-; L-α-Aspartyl-L-valyl-L-valyl-L-α-aspartyl-L-alanyl-L-α-aspartyl-L-α-glutamyl-L-tyrosyl-L-leucyl-L-isoleucyl-L-prolyl-L-glutamine; H-Asp-Val-Val-Asp-Ala-Asp-Glu-Tyr-Leu-Ile-Pro-Gln-OH; Epidermal Growth Factor Receptor Peptide. Grades: ≥95%. CAS No. 96249-43-3. Molecular formula: C61H93N13O23. Mole weight: 1376.46. | |
| EGFR/ErbB2 Inhibitor | EGFR/ErbB2 inhibitor is a cell-permeable 4-anilino quinazoline compound, which is a potent and reversible inhibitor of EGFR and c-ErbB2 (IC50s = 20 and 79 nM, respectively). It inhibits the proliferation of cancer cells overexpressing either c-ErbB2 or EGFR (IC50s = 2.3-2.5 μM). Synonyms: 4557W; 4-(4-Benzyloxyanilino)-6,7-dimethoxyquinazoline; EGFR/ErbB-2 Inhibitor. Grades: ≥95%. CAS No. 179248-61-4. Molecular formula: C23H21N3O3. Mole weight: 387.4. | |
| EGFR-IN-2 | EGFR-IN-2 is a a noncovalent, irreversible, mutant-selective second generation EGFR inhibitor. It showed excellent cellular activity against both the single and double mutants of EGFR, demonstrating target engagement in vivo and ADME-PK properties that are suitable for further evaluation. CAS No. 1643497-70-4. Molecular formula: C26H33N9O3S. Mole weight: 551.66. | |
| EGFR-IN-24 | EGFR-IN-24, a potent EGFR inhibitor, shows inhibition against EGFR(del19/T790M/C797S) and EGFR(L858R/T790M/C797S), respectively [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2757548-54-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-142512. | |
| EGFR-IN-47 | EGFR-IN-47 is a potent and orally active EGFR L858R/T790M/C797S inhibitor with an IC 50 of 0.01 μM. EGFR-IN-47 induces cell cycle attest and cell apoptosis. EGFR-IN-47 has the potential for the research of NSCLC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3034649-73-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143337. | |
| EGFR-IN-5 | EGFR-IN-5 is a EGFR inhibitor with IC 50 s of 10.4, 1.1, 34, 7.2 nM for EGFR, EGFR L858R , EGFR L858R/T790M , and EGFR L858R/T790M/C797S , respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 2225887-26-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111415. | |
| EGFR-IN-69 | EGFR-IN-69 (compound 17g) is a potent EGFR inhibitor, with IC 50 values of 4.3, 6.6 and 25.6 nM against EGFR L858R/T790M/C797S , EGFR L858R/T790M , and EGFR 19del/T790M/C797S , respectively. EGFR-IN-69 can be used for non-small-cell-lung-cancer (NSCLC) research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2433837-65-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150610. | |
| EGFR-IN-7 | EGFR-IN-7 Inhibitor. Uses: Scientific use. Product Category: T11161. CAS No. 2267329-76-8. |  |
| EGFR-IN-70 | EGFR-IN-70 (compound 18j) is a potent EGFR inhibitor with IC 50 values of 23.6 and 307.5 nM for EGFR LR/TM/CS and EGFR WT , respectively. EGFR-IN-70 has anti-proliferative activity and suppresses phosphorylation of the EGFR. EGFR-IN-70 can be used for cancer research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2926716-96-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-150611. | |
| EGFR-IN-78 | EGFR-IN-78 (compound A5), a 2-aminopyrimidine derivative, is a reversible inhibitor of EGFR C797S -TK, and also an inducer of apoptosis. EGFR-IN-78 shows anti-proliferative activity, inhibits EGFR phosphorylation and arrests cell cycle at G2/M phase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3042104-73-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-149889. | |
| EGFR-IN-8 | EGFR-IN-8 is a dual EGFR and c-Met inhibitor, compound 48. EGFR-IN-8 can be a promising candidate for further development to target EGFR TKI-resistant NSCLC [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2407957-87-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126320. | |
| EGFR-IN-86 | EGFR-IN-86 (compound 4i) is an EGFR inhibitor ( IC 50 : 1.5 nM) with high activity against glioblastoma. EGFR-IN-86 induces apoptosis and arrests the U87 cell cycle in the G2/M phase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3055550-22-3. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149530. | |
| EGFR-IN-89 | EGFR-IN-89 (compound 13k) is a potent, fourth-generation EGFR mutation inhibitor with an IC 50 of 10.1 nM against Del19/T790M/C797S mutations. EGFR-IN-89 shows higher selectivity over wild type [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2413029-40-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-156284. | |
| EGFR-IN-95 | EGFR-IN-95 (compound 5j) is an 2,4-diaminonicotinamide derivative. EGFR-IN-95 has potent inhibitory activity against EGFR del19/T790M/C797S and L858R/T790M/C797S [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3027135-04-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-163094. | |
| EGFR Inhibitor | A cell-permeable and highly selective EGFR tyrosine kinase inhibitor with IC50 value in the nanomolar range. Inhibition of EGFR induces apoptosis of tumor cells by ownregulating antiapoptotic proteins such as survivin and upregulating proapoptotic proteins such as Bim. Uses: Antitumor agent. Synonyms: EGFR inhibitor; EGFR-inhibitor; EGFRinhibitor; Cyclopropanecarboxylic acid-(3-(6-(3-trifluoromethyl-phenylamino)-pyrimidin-4-ylamino)-phenyl)-amide; N- (3- ( (6- ( (3- (Trifluoromethyl) phenyl) amino) pyrimidin-4-yl) amino) phenyl) cyclopropanecarboxamide; K00598a. Grades: 99%. CAS No. 879127-07-8. Molecular formula: C21H18F3N5O. Mole weight: 413.4. | |
| EGFR kinase inhibitor 3 | EGFR kinase inhibitor 3 (compound 2) is a bivalent ATP-allosteric EGFR kinase inhibitor with IC 50 s of <10 nM, 1.5 nM, 0.059 nM, 0.064 nM for WT EGFR, EGFR-activating mutations L858R, L858R/T790M and L858R/T790M/C797S, respectively. EGFR kinase inhibitor 3 is a C-linked inhibitor [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2922402-03-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-162299. | |
| EGFR mutant-IN-2 | EGFR mutant-IN-2 (Compound D51) is an EGFR mutant inhibitor. EGFR mutant-IN-2 inhibits the EGFR L858R/T790M/C797S mutant with an IC 50 value of 14 nM. EGFR mutant-IN-2 inhibits the EGFR del19/T790M/C797S mutant with an IC 50 value of 62 nM. EGFR mutant-IN-2 has favorable PK parameters, safety properties, in vivo stability, and antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2770009-06-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-155005. | |
| EGFR T790M/L858R-IN-8 | EGFR T790M/L858R-IN-8 (compound 9) is a potent inhibitor of EGFR , targeting mutant EGFR T790M/L858R with IC 50 of 56.8 μM. The anti-proliferative effect of EGFR T790M/L858R-IN-8 on cancer cell lines A549, A431, and NHI-H1975 is not significant [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 333419-97-9. Pack Sizes: 5 mg; 10 mg. Product ID: HY-164056. | |
| EGFR-TK-IN-4 | EGFR-TK-IN-4 (compound 10k) is a potent and selective EGFR-TK inhibitor. EGFR-TK-IN-4 can induce apoptosis. EGFR-TK-IN-4 has antitumor activity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3053485-72-3. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-161927. | |
| Eggmanone | Eggmanone is a potent and selective phosphodiesterase (PDE) 4 inhibitor (IC50 = 72 nM) displaying >40-fold selectivity over PDE3, PDE10, and PDE11. Eggmanone acts via blocking hedgehog signaling through PDE antagonism, downstream of smoothened signaling. Synonyms: 5,6,7,8-Tetrahydro-3-(2-methyl-2-propen-1-yl)-2-[[2-oxo-2-(2-thienyl)ethyl]thio]-[1]benzothieno[2,3-d]pyrimidin-4(3H)-one. Grades: ≥98% by HPLC. CAS No. 505068-32-6. Molecular formula: C20H20N2O2S3. Mole weight: 416.58. | |
| Egg oil | Egg oil is a natural oil, which consists primarily of cholesterol, lecithin and glycerides of the fatty acids. Egg oil exhibits activity in regulating the gut microbial dysbiosis, alleviating obesity, insulin resistance and inflammation [1] [2] [3] [4]. Uses: Scientific research. Group: Natural products. CAS No. 8001-17-0. Pack Sizes: 25 mg; 50 mg. Product ID: HY-N12670. | |
| Egg PC (60%) | Egg PC (60%). Group: Others. L-α-phosphatidylcholine (Egg, Chicken-60%) (Total Egg Phosphatide Extract); Egg PC (60%). Cat No: PHOZ-245. | |
| Egg phosphatidylglycerol | Egg phosphatidylglycerol. Synonyms: EPG. CAS No. 383907-64-0. Product ID: PE-0569. Molecular formula: C40H76NaO10P. Mole weight: 782.284. Category: Emulsifier. Product Keywords: Excipients for Liquid Dosage Form; Emulsifier Excipients; PE-0569; Egg phosphatidylglycerol; Emulsifier; C40H76NaO10P; 383907-64-0. UNII: NA. Chemical Name: 1, 2-Diacyl-sn-Glycero-3-Phospho-[1-rac-glycerol]. Grade: Pharmceutical Excipients. Administration route: Intravenous injection. Dosage Form: Intravenous injection. Stability and Storage Conditions: Soluble in chloroform, slightly soluble in ethanol, insoluble in water. This product should be dark, sealed, frozen transportation and storage, avoid storage with strong oxidizing substances. Proper use and preservation of the condition of quality can be guaranteed for three years. Phospholipids can be hydrolyzed in strong acid and base environments, so contact with strong acid or base media should be avoided except for strong oxidizing substances. Commonly used amount and the maximum amount: The maximum dosage of intravenous injection is 0.36mg. |  |
| Egg Phospholipids | Egg Phospholipids. Synonyms: E322; egg lecithin; LSC 5050; LSC 6040; mixed soybean phosphatides; ovolecithin; Phosal 53 MCT; Phospholipon 100 H; ProKote LSC; soybean lecithin; soybean phospholipids; Sternpur; vegetable lecithin. CAS No. 93685-90-6. Product ID: PE-0429. Category: Dispersants; Emollient; emulsifying agent. Product Keywords: Pharmaceutical Excipients; Excipients for Liquid Dosage Form; Egg Phospholipids; Dispersion Excipients; Dispersants; Emollient; emulsifying agent; 93685-90-6; 93685-90-6. UNII: 1Z74184RGV. Chemical Name: Egg yolk lecithin. Grade: Pharmceutical Excipients. Administration route: Intravenous, oral. Dosage Form: Injection, Emulsion, Powder lyophilized, for soultion, Tablet. | |
| Egg Powder (Fipronil) | Egg Powder (Fipronil). Uses: For analytical and research use. Group: Pesticides & metabolites. Catalog: APS007745. |  |
| Egg yolk lecithin | Lecithins vary greatly in their physical form, from viscous semiliquids to powders, depending upon the free fatty acid content. They may also vary in color from brown to light yellow, depending upon whether they are bleached or unbleached or on the degree of purity. When they are exposed to air, rapid oxidation occurs, also resulting in a dark yellow or brown color. Lecithins have practically no odor. Those derived from vegetable sources have a bland or nutlike taste, similar to that of soybean oil. Synonyms: E322; egg lecithin; LSC 5050; LSC 6040; mixed soybean phosphatides; ovolecithin; Phosal 53 MCT; Phospholipon 100 H; ProKote LSC; soybean lecithin; soybean phospholipids; Sternpur; vegetable lecithin. CAS No. 93685-90-6. Product ID: PE-0112. Category: Emollient; Emulsifying Agents; Solubilizing Agents. Product Keywords: Humectants Excipients; Stabilizers; Emulsifier & Suspending Agents; ; PE-0112; Egg yolk lecithin; Emollient; Emulsifying Agents; Solubilizing Agents; ; 93685-90-6. UNII: 1Z74184RGV. Chemical Name: Egg Phospholipids. Grade: Pharmceutical Excipients. Administration route: Intravenous, oral. Dosage Form: Injection, Emulsion, Powder lyophilized, for soultion, Tablet. Stability and Storage Conditions: Lecithins decompose at extreme pH. They are also hygroscopic and subject to microbial degradation. When heated, lecithins oxidize, darken, and decompose. Temperatures of 160-180°C will cause degradatio | |
| Egg yolk phosphatidylcholines | Egg yolk phosphatidylcholines. Group: Biochemicals. CAS No. 93685-90-6. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| EGIS-8332 | EGIS-8332 potently decreased AMPA and quisqualate induced LDH release (IC50 = 5.2 ± 0.4 and 7.4 ± 1.3 μM, respectively) from the cells. The inhibition of the AMPA/kainate ion channels by EGIS-8332 is non-competitive, not use dependent, and depends neither on the closed/open state of the channel, nor the membrane potential. Synonyms: 7-acetyl-5-(4-aminophenyl)-8-methyl-9H-[1,3]dioxolo[4,5-h][2,3]benzodiazepine-8-carbonitrile; EGIS-8332; EGIS 8332; EGIS8332. Grades: >98%. CAS No. 220725-87-1. Molecular formula: C20H18N4O3. Mole weight: 362.389. | |
| Eglin c(41-49) | Heterocyclic Organic Compound. Alternative Names: EGLIN C (41-49);H-SER-PRO-VAL-THR-LEU-ASP-LEU-ARG-TYR-OH;SER-PRO-VAL-THR-LEU-ASP-LEU-ARG-TYR. CAS No. 122299-11-0. Molecular formula: C48H78N12O15. Mole weight: 1063.2043. Purity: 0.96. IUPACName: (3S)-4-[[(2S)-1-[[(2S)-5-(diaminomethylideneamino)-1-[[(2S)-1-[[(2S)-1,3-dihydroxy-1-oxopropan-2-yl]amino]-3-(4-hydroxyphenyl)-1-oxopropan-2-yl]amino]-1-oxopentan-2-yl]amino]-4-methyl-1-oxopentan-2-yl]amino]-3-[[(2S)-2-[[(2S,3R)-3-hydroxy-2-[[(2S)-3-methy. Canonical SMILES: CC (C)CC (C (=O)NC (CCCN=C (N)N)C (=O)NC (CC1=CC=C (C=C1)O)C (=O)NC (CO)C (=O)O)NC (=O)C (CC (=O)O)NC (=O)C (CC (C)C)NC (=O)C (C (C)O)NC (=O)C (C (C)C)NC (=O)C2CCCN2. Density: 1.44 g/cm³. Catalog: ACM122299110. |  |
| EGLU | EGLU is a group II mGluR antagonist and also a selective antagonist of presynaptically-mediated (1S,3S)-ACPD-induced depression of motoneuron excitation in neonatal rat spinal cord. Synonyms: (2S)-α-Ethylglutamic acid; (2S)-2-amino-2-ethylpentanedioic acid. Grades: ≥95% by HPLC. CAS No. 170984-72-2. Molecular formula: C7H13NO4. Mole weight: 175.18. | |
| Egomaketone | Egomaketone. Uses: For analytical and research use. Group: Impurity standards. CAS No. 59204-74-9. Molecular Formula: C10H12O2. Mole Weight: 164.2. Catalog: APB59204749. | |
| egonol oleate | egonol oleate. CAS No. 1027369-38-5. Molecular formula: C37H50O6. Catalog: ACM1027369385. | |
| Egt1442 | Heterocyclic Organic Compound. Alternative Names: EGT1442; (1S) -1, 5-Anhydro-1-C-[4-chloro-3-[[4-[2- (cyclopropyloxy) ethoxy]phenyl]methyl]phenyl]-D-glucitol; Bexagliflozin. CAS No. 1118567-05-7. Molecular formula: C24H29ClO7. Density: 1.41. Catalog: ACM1118567057. | |
| EGT1442 | EGT1442 is a potent and selective SGLT2 inhibitor with IC50 value of 5.6 μM /2 nM in SGLT1 /SGLT2 respectively. It significantly prolonged the median survival of SHRSP rats. It attenuates blood glucose and HbA(1c) levels and prolongs the survival of stroke-prone rats in db/db mice. It showed favorable properties both in vitro and in vivo and could be beneficial to the management of type 2 diabetic patients. It was developed by Theracos and in clinic phase 1 trials. Uses: Egt1442 showed favorable properties and could be beneficial to the management of type 2 diabetic patients. Synonyms: THR1442; THR-1442; THR 1442; EGT1442; EGT-1442; EGT 1442; Bexagliflozin; (1S) -1, 5-Anhydro-1-C-[4-chloro-3-[[4-[2- (cyclopropyloxy) ethoxy]phenyl]methyl]phenyl]-D-glucitol; Bexagliflozin; THR1442; EGT0001442; EGT-1442; THR-1442; EGT-0001442; (2S, 4R, 6R) -2- (4-chloro-3- (4- (2-cyclopropoxyethoxy) benzyl) phenyl) -6- (hydroxymethyl) tetrahydro-2H-pyran-3, 4, 5-triol; (3R, 4R, 5S, 6R) -2- (4-chloro-3- (4- (2-cyclopropoxyethoxy) benzyl) phenyl) -6- (hydroxymethyl) tetrahydro-2H-pyran-3, 4, 5-triol. Grades: >98%. CAS No. 1118567-05-7. Molecular formula: C24H29ClO7. Mole weight: 464.94. | |
| EGTA | Chelating agent for the determination of calcium. Group: Biochemicals. Alternative Names: Ethyleneglycol-bis-(2 aminoethylether)-N,N.N,N-tetraacetic acid; Glycol ether diamine tetraacetic acid; Egtazic acid. Grades: Molecular Biology Grade. CAS No. 67-42-5. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C14H24N2O10, Molecular Weight: 380.35. US Biological Life Sciences. | Worldwide |
| EGTA | 25g Pack Size. Group: Biochemicals, Ligands. Formula: C14H24N2O10. CAS No. 67-42-5. Prepack ID 29346817-25g. Molecular Weight 380.35. See USA prepack pricing. |  |
| EGTA | EGTA is a specific calcium ion chelator. EGTA has an apparent calcium dissociation constant (K d ) of 60.5 nM at physiological pH (7.4) and has very high specificity for Ca 2+ over Mg 2+ (Mg 2+ K d 1-10 mM). EGTA significantly inhibits the substrate adherence capacity of inflammatory macrophages [1] [2]. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 67-42-5. Pack Sizes: 500 mg; 1 g. Product ID: HY-D0861. | |
| EGTA tetrasodium | EGTA tetrasodium. Group: Biochemicals. Alternative Names: Ethylene glycol-bis(beta-aminoethyl ether)-N,N,N',N'-tetraacetic acid tetrasodium salt. Grades: Highly Purified. CAS No. 13368-13-3. Pack Sizes: 5g, 10g, 25g, 50g, 100g. Molecular Formula: C14H20N2O10·4Na. US Biological Life Sciences. | Worldwide |
| EH44 | ≥99% (HPLC). Uses: Eh44 is a li+ free, hydrophobic hole transporting material (htm). it eliminates degradation due to li+ migration, supresses degradation due to moisture absorption and thus showed promise for achieving long-term stability in fabricated perovskite solar cells. using eh44 as htm in a device configuration of: sno2/pal/eh44/moox /al, not only generated high power conversion efficiency (pce) comparable. Group: Perovskite materials. Alternative Names: 9-(2-Ethylhexyl)-N,N,N,N-tetrakis(4-methoxyphenyl)- 9H-carbazole-2,7-diamine). CAS No. 1879076-81-9. Molecular formula: CuSCN. Mole weight: 733.94 g/mol. Appearance: powder. Purity: ≥99%HPLC. Canonical SMILES: CCC (CCCC)CN1C2=CC (N (C3=CC=C (OC)C=C3)C4=CC=C (OC)C=C4)=CC=C2C5=CC=C (N (C6=CC=C (OC)C=C6)C7=CC=C (OC)C=C7)C=C15. Catalog: ACM1879076819-1. | |
| EH-IDTBR | EH-IDTBR. Group: Organic field effect transistor (ofet) materials organic solar cell (opv) materials. Product ID: (5Z)-3-ethyl-2-sulfanylidene-5-[[4-[9, 9, 18, 18-tetrakis(2-ethylhexyl)-15-[7-[(Z)-(3-ethyl-4-oxo-2-sulfanylidene-1, 3-thiazolidin-5-ylidene)methyl]-2, 1, 3-benzothiadiazol-4-yl]-5, 14-dithiapentacyclo[10.6.0.03, 10.04, 8.013, 17]octadeca-1(12), 2, 4(8), 6, 10, 13(17), 15-heptaen-6-yl]-2, 1, 3-benzothiadiazol-7-yl]methylidene]-1, 3-thiazolidin-4-one. Molecular formula: 1326g/mol. Mole weight: C72H88N6O2S8. CCCCC (CC)CC1 (C2=CC3=C (C=C2C4=C1C=C (S4)C5=CC=C (C6=NSN=C56)C=C7C (=O)N (C (=S)S7)CC)C (C8=C3SC (=C8)C9=CC=C (C1=NSN=C91)C=C1C (=O)N (C (=S)S1)CC) (CC (CC)CCCC)CC (CC)CCCC)CC (CC)CCCC. InChI=1S/C72H88N6O2S8/c1-11-21-25-43 (15-5)39-71 (40-44 (16-6)26-22-12-2)53-35-52-54 (36-51 (53)65-55 (71)37-57 (83-65)49-31-29-47 (61-63 (49)75-87-73-61)33-59-67 (79)77 (19-9)69 (81)85-59)72 (41-45 (17-7)27-23-13-3, 42-46 (18-8)28-24-14-4)56-38-58 (84-66 (52)56)50-32-30-48 (62-64 (50)76-88-74-62)34-60-68 (80)78 (20-10)70 (82)86-60/h29-38, 43-46H, 11-28, 39-42H2, 1-10H3/b59-33-, 60-34-. HKJHYTKBDDVGRK-IOUDQCQMSA-N. |  |
| EH-IDTBR | Band gap: 1.68 eV. Group: N-type small molecules. CAS No. 2102510-60-9. Mole weight: 1326.03. Catalog: ACM2102510609. | |
| EHNA hydrochloride | EHNA hydrochloride is a potent and selective dual inhibitor of cyclic nucleotide phosphodiesterase 2 (PDE2) ( IC 50 =4 μM) and adenosine deaminase (ADA). EHNA hydrochloride exerts a concentration inhibition of the cGMP-stimulated PDE II (cGs-PDE)( IC 50 :0.8 μM (human), 2 μM (porcine myocardium)), but has smaller inhibitory effect on the unstimulated PDE2 activity. EHNA hydrochloride play roles in mediating diverse pharmacological responses, including antiviral, antitumour and antiarrhythmic effects [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 58337-38-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg. Product ID: HY-103160A. | |
| EHNA hydrochloride | EHNA hydrochloride is a selective inhibitor of cGMP-stimulated phosphodiesterase (PDE2) (IC50 = 0.8 - 4 μM) and also an inhibitor of adenosine deaminase. EHNA inhibits spontaneous differentiation of human ESCs in feeder-free conditions and directed neuronal differentiation. Uses: Antiviral agents. Synonyms: (2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol hydrochloride. Grades: >98%. CAS No. 58337-38-5. Molecular formula: C14H23N5O.HCl. Mole weight: 313.83. | |
| EHNA hydrochloride | EHNA hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 81408-49-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| EHNA Hydrochloride (NSC263164, EHNA HCl, Adenosine deaminase inhibitor, 9H-Purine-9-ethanol, monohydrochloride) | EHNA Hydrochloride (NSC263164, EHNA HCl, Adenosine deaminase inhibitor, 9H-Purine-9-ethanol, monohydrochloride). Group: Biochemicals. Alternative Names: (2S,3R)-3-(6-aminopurin-9-yl)nonan-2-ol;hydrochloride. Grades: Highly Purified. CAS No. 58337-38-5. Pack Sizes: 25mg. Molecular Formula: C14 H23 N5, Molecular Weight: 313.8. US Biological Life Sciences. | Worldwide |
| EHop-016 | EHop-016 is a rac GTPase inhibitor that blocks the interaction of Rac with GEF Vav in metastatic human breast cancer cells. Synonyms: N4-(9-Ethyl-9H-carbazol-3-yl)-N2-(3-morpholinopropyl)pyrimidine-2,4-diamine; N4-(9-Ethyl-9H-carbazol-3-yl)-N2-[3-(4-morpholinyl)propyl]-2,4-pyrimidinediamine. Grades: 98%. CAS No. 1380432-32-5. Molecular formula: C25H30N6O. Mole weight: 430.5. | |
| EHop-016 | EHop-016 is a potent and selective Rac GTPase Rac1 and Rac3 inhibitor. EHop-016 inhibits Rac1 activity with an IC 50 of 1.1 μM in MDA-MB-435 cells. EHop-016 inhibits Vav2 interaction with Rac, Rac-activated PAK1, lamellipodia formation, and cell migration [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1380432-32-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12810. | |
| Ehp-inhibitor-1 | Ehp-inhibitor-1 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Synonyms: 6-(3-methoxyphenyl)-3-pyridin-3-ylpyrazolo[1,5-a]pyrimidin-7-amine. CAS No. 861249-59-4. Molecular formula: C18H15N5O. Mole weight: 317.352. | |
| Ehp-inhibitor-2 | Ehp-inhibitor-2 is an Eph family tyrosine kinase inhibitor targeting Eph receptors. Study indicated that inhibition of Eph receptors results in an increase in glucose-stimulated insulin secretion from mouse and human pancreatic islets. Synonyms: 3-(7-amino-3-(pyridin-3-yl)pyrazolo[1,5-a]pyrimidin-6-yl)phenol. CAS No. 861249-77-6. Molecular formula: C17H13N5O. Mole weight: 303.325. | |
| EHT 1864 | EHT 1864 is an inhibitor of Rac family small GTPases. EHT 1864 directly binds and impairs the ability of this small GTPase to engage critical downstream effectors required for growth transformation. The K d values are 40, 50, 60, and 230 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. EHT 1864 also potently inhibits other Rac-dependent transformation processes, Tiam1- and Ras-mediated growth transformation. EHT 1864 prevents Aβ 40 and Aβ 42 production in vivo. EHT 1864 dependently suppresses the release of migrasomes from podocytes induced by LPS, PAN, or HG [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 754240-09-0. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16659. | |
| EHT 1864 | EHT 1864 is a potent Rac family GTPase inhibitor with Kd of 40 nM, 50 nM, 60 nM and 250 nM for Rac1, Rac1b, Rac2 and Rac3, respectively. Synonyms: EHT 1864; EHT1864; EHT-1864. Grades: >98%. CAS No. 754240-09-0. Molecular formula: C25H29Cl2F3N2O4S. Mole weight: 581.47. | |
| EHT-6706 | EHT-6706 is a novel microtubule-disrupting agent that targets the colchicine-binding site to inhibit tubulin polymerization. At low nM concentrations, EHT 6706 exhibits highly potent antiproliferative activity on more than 60 human tumor cell lines, even those described as being drug resistant. EHT 6706 also shows strong efficacy as a vascular-disrupting agent, since it prevents endothelial cell tube formation and disrupts pre-established vessels, changes the permeability of endothelial cell monolayers and inhibits endothelial cell migration. Genome-wide transcriptomic analysis of EHT 6706 effects on human endothelial cells shows that the antiangiogenic activity elicits gene deregulations of antiangiogenic pathways. These findings indicate that EHT 6706 is a promising tubulin-binding compound with potentially broad clinical antitumor efficacy. Synonyms: EHT6706; EHT 6706; EHT-6706. CAS No. 1351592-10-3. Molecular formula: C21H24N2O4. Mole weight: 368.43. | |
| EHT-6706 dihydrochloride | EHT-6706 can target the colchicine-binding site to inhibit tubulin polymerization as a tubulin polymerisation inhibitor. It is under the development of Diaxonhit. EHT 6706 also is a vascular-disrupting agent. It can prevent endothelial cell tube formation and disrupt pre-established vessels, change the permeability of endothelial cell monolayers and inhibit endothelial cell migration. In Jul 2013, preclincal development for treatment of cancer was ongoing in the USA. Uses: Cancer. Synonyms: EHT-6706 dihydrochloride; EHT 6706 dihydrochloride; EHT6706 dihydrochloride; 7-ethoxy-4-(3,4,5-trimethoxybenzyl)isoquinolin-8-amine dihydrochloride. Grades: 98%. CAS No. 1351592-09-0. Molecular formula: C21H26Cl2N2O4. Mole weight: 441.35. | |
| Ehtyl Alcohol 200 Proof | Ehtyl Alcohol 200 Proof Alternative Name: Ethanol- 200 proof//Denatured Alcohol. Grade: 100%/200 proof. CAS Number: 64-17-5. |  Los Angeles, CA 90023 |
| EI1 | EI1 (KB-145943) is a potent and selective EZH2 inhibitor with IC 50 of 15 nM and 13 nM for EZH2 (WT) and EZH2 (Y641F), respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: KB-145943. CAS No. 1418308-27-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15573. | |
| EI1 | EI1 inhibits cellular H3K27 methylation and activates Ezh2 target gene p16 expression. Synonyms: EI1; ei-1; KB-145943; 6-cyano-N-[(4,6-dimethyl-2-oxo-1H-pyridin-3-yl)methyl]-1-pentan-3-ylindole-4-carboxamide; 6-Cyano-N-((4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-1-(pentan-3-yl)-1H-indole-4-carboxamide; 6-Cyano-N-[(1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl]-1-(1-ethylpropyl)-1H-indole-4-carboxamide; 6-cyano-N-[(4,6-dimethyl-2-oxo-1,2-dihydropyridin-3-yl)methyl]-1-(pentan-3-yl)-1H-indole-4-carboxamide; 6-cyano-n-((1,2-dihydro-4,6-dimethyl-2-oxo-3-pyridinyl)methyl)-1-(1-ethylpropyl)-1h-indole-4-carboxamide; EI1; Ezh2 inhibitor; Ezh2 inhibitor; EI-1; EI 1; GTPL7013; SCHEMBL16197843; DTXSID101111134; BCP23699; EX-A2431; s7611; AKOS030526508; CCG-268533; CS-1654; SB19343; NCGC00351776-01; NCGC00351776-03; AC-36069; AS-55788; HY-15573; C72647; A911213; Q27077166. Grades: >98%. CAS No. 1418308-27-6. Molecular formula: C23H26N4O2. Mole weight: 390.48. | |
| EI-1507-1 | EI-1507-1 is produced by the strain of Streptomyces sp. E-1507. It had weak antibacterial activity, and it inhibited ICE with an IC50 of 0.23 μmol/L. Molecular formula: C20H18O6. Mole weight: 354.35. | |
| EI-1507-2 | EI-1507-2 is produced by the strain of Streptomyces sp. E-1507. It had weak antibacterial activity, and it inhibited ICE with an IC50 of 0.42 μmol/L. Molecular formula: C20H20O6. Mole weight: 356.37. | |
| EI-1511-3 | It is produced by the strain of Streptomyces sp. E-1511. EI-1511-3 inhibited recombinant human ICE with an IC50 of 0.09 μmol/L. Synonyms: (2E,4E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-7-methylocta-2,4-dienamide. Molecular formula: C27H30N2O7. Mole weight: 494.54. | |
| EI-1511-5 | It is produced by the strain of Streptomyces sp. E-1511. EI-1511-5 inhibited recombinant human ICE with an IC50 of 0.38 μmol/L. Synonyms: (2E,4E,6E)-N-[(1S,5S,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-8-methyldeca-2,4,6-trienamide. Molecular formula: C29H32N2O7. Mole weight: 520.57. | |
| EI-1625-2 | It is produced by the strain of Streptomyces sp. E-1625. EI-1625-2 inhibited recombinant human ICE with an IC50 of 0.2 μmol/L. Synonyms: (2E)-N-[(1S,5R,6R)-5-hydroxy-5-{(1E,3E,5E)-7-[(2-hydroxy-5-oxocyclopent-1-en-1-yl)amino]-7-oxohepta-1,3,5-trien-1-yl}-2-oxo-7-oxabicyclo[4.1.0]hept-3-en-3-yl]-4-methyloct-2-enamide. Molecular formula: C27H32N2O7. Mole weight: 496.55. | |
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