A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
An impurity of Gefitinib. Gefitinib is an EGFR inhibitor. It is used for the treatment of certain breast, lung and other cancers. Synonyms: 3,4-Dihydro-4-oxo-6-acetoxy-7-methoxyquinazoline; 6-(Acetyloxy)-7-methoxy-4(3H)-quinazolinone; 3,4-Dihydro-7-methoxy-4-oxoquinazolin-6-yl acetate; Gefitinib interMidiate IV; 7-Methoxy-4-oxo-3,4-dihydroquinazolin-6-yl acetate. Grade: > 95%. CAS No. 179688-53-0. Molecular formula: C11H10N2O4. Mole weight: 234.21.
Gefitinib Impurity VIII
Gefitinib Impurity VIII. Synonyms: 4-[(3-Chloro-4-fluorophenyl)amino]-7-methoxy-6-quinazolinol 6-acetate; 4-(3-Chloro-4-fluorophenylamino)-7-methoxyquinazolin-6-yl acetate; 6-Quinazolinol,4-[(3-chloro-4-fluorophenyl)amino]-7-methoxy-, 6-acetate; Gefitinib intermediate VI. Grade: > 95%. CAS No. 788136-89-0. Molecular formula: C17H13ClFN3O3. Mole weight: 361.76.
Gefitinib N-oxide is the N-oxide derivative of Gefitinib. Synonyms: Gefitinib Morpholine N-oxide; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-oxido-4-morpholinyl)propoxy]-4-quinazolinamine; 4-(3-((4-((3-chloro-4-fluorophenyl)amino)-7-methoxyquinazolin-6-yl)oxy)propyl)morpholine 4-oxide. Grade: > 95%. CAS No. 847949-51-3. Molecular formula: C22H24ClFN4O4. Mole weight: 462.91.
Gefitinib (ZD1839)
Gefitinib is an EGFR inhibitor for Tyr1173, Tyr992, Tyr1173 and Tyr992 in the NR6wtEGFR and NR6W cells with IC50 of 37 nM, 37nM, 26 nM and 57 nM, respectively. Gefitinib promotes autophagy and apoptosis of lung cancer cells via blockade of the PI3K/AKT / mTOR pathway. Group: Inhibitors. Alternative Names: ZD1839. CAS No. 184475-35-2. Pack Sizes: 100mg. Product ID: S1025. Formula: C22H24ClFN4O3. Smiles: COC1=C(C=C2C(=C1)N=CN=C2NC3=CC(=C(C=C3)F)Cl)OCCCN4CCOCC4. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Gefurulimab
Gefurulimab (ALXN-1720) is a high-affinity antibody inhibitor targeting complement protein C5, which can specifically bind to C5 and inhibit its cleavage into C5a and C5b. Gefurulimab can block the activation of the terminal complement pathway and reduce inflammatory damage. Gefurulimab can effectively reduce the formation of membrane attack complex (MAC) and has good pharmacokinetic properties. Gefurulimab can be used to study kidney and autoimmune diseases related to abnormal activation of the complement system, such as IgA nephropathy, lupus nephritis, and myasthenia gravis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ALXN-1720. CAS No. 2456407-94-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99638.
geissoschizine dehydrogenase
Involved in the interconversion of heteroyohimbine alkaloids in Catharanthus roseus. Group: Enzymes. Enzyme Commission Number: EC 1.3.1.36. CAS No. 84399-94-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1308; geissoschizine dehydrogenase; EC 1.3.1.36; 84399-94-0. Cat No: EXWM-1308.
Geissoschizine methyl ether
Geissoschizine methyl ether is an indole alkaloid isolated from Uncariae hooks. Geissoschizine methyl ether acts as a 5-HT7 receptor antagonist and also a potent acetylcholinesterase (AChE) inhibitor. Synonyms: Methyl (Z)-2-[(2S,3E,12bS)-3-ethylidene-2,4,6,7,12,12b-hexahydro-1H-indolo[2,3-a]quinolizin-2-yl]-3-methoxyprop-2-enoate. Grade: 98.0%. CAS No. 60314-89-8. Molecular formula: C22H26N2O3. Mole weight: 366.461.
Gelastatin A
It is produced by the strain of Westerdykella multispora F50733. It can inhibit the activity of leucinase A and the IC50 of leucinase A is 0.63 μmol/L. Synonyms: (all-E)-5-(2,4-Hexadienylidene)-5,6-dihydro-2-oxo-2H-pyran-3-propanoic acid. Grade: ≥98%. Molecular formula: C14H16O4. Mole weight: 248.27.
Gelatin. CAS No. 9000-70-8. Product ID: PE-0255. Category: Drop Pill Base. Product Keywords: Pharmaceutical Excipients; Semi-solid Dosage Form; Drop Pill Base; Gelatin; PE-0255; 9000-70-8; 9000-70-8. EC Number: 232-554-6.
Gelatin
Gelatin occurs as a light-amber to faintly yellow-colored, vitreous, brittle solid. It is practically odorless and tasteless, and is available as translucent sheets, flakes, and granules, or as a coarse powder. Synonyms: Byco; Cryogel; E441; gelatina; gelatine; Instagel; Kolatin; Solugel; Vitagel. CAS No. 9000-70-8. Product ID: PE-0070. Category: Coating Agents; Film-forming Agents; Gelling Agents; Suspending Agents; Tablet Binder; Viscosity-increasing Agents. Product Keywords: Binder Excipients; Suspending Agents; PE-0070; Gelatin; Coating Agents; Film-forming Agents; Gelling Agents; Suspending Agents; Tablet Binder; Viscosity-increasing Agents; ; 9000-70-8. UNII: 2G86QN327L. Chemical Name: Gelatin. Grade: Pharmceutical Excipients. Administration route: Dental; inhalations; injections; oral; topical and vaginal. Dosage Form: Dental preparations; inhalations; injections; oral capsules, pastilles, solutions, syrups and tablets; topical and vaginal preparations. Stability and Storage Conditions: Dry gelatin is stable in air. Aqueous gelatin solutions are also stable for long periods if stored under cool conditions but they are subject to bacterial degradation. At temperatures above about 50°C, aqueous gelatin solutions may undergo slow depolymerization and a reduction in gel strength may occur on resetting. Depolymerization becomes more rapid at temperatures above 65°C, and gel strength may be reduced by half when a solution i
Gelatin empty capsule is composed of cap and body made from medicinal gelatin and auxiliary materials to be embedded with solid drugs such as homemade powder, health care products, drugs etc., so that the poor taste problem can be solved for patients. Besides, words, trademarks and images can be printed on the capsules to present customers unique image. Product ID: PE-0162. Category: Capsule Excipients. Product Keywords: Pharmaceutical Excipients; Capsule Excipients; Gelatin; PE-0162.
Gelatin, 250 Bloom
Gelatin, 250 Bloom
gelatinase A
A secreted endopeptidase in peptidase family M10 (interstitial collagenase family), but possessing an additional fibronectin-like domain. Group: Enzymes. Synonyms: 72-kDa gelatinase; matrix metalloproteinase 2; type IV collagenase (ambiguous); 3/4 collagenase (obsolete); matrix metalloproteinase 5 (obsolete); 72 kDa gelatinase type A; collagenase IV (ambiguous); collagenase type IV (ambiguous); MMP 2; type IV collagen metalloproteinase (ambiguous); type IV collagenase/gelatinase (ambiguous). Enzyme Commission Number: EC 3.4.24.24. CAS No. 146480-35-5. Matrix Metalloproteinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4305; gelatinase A; EC 3.4.24.24; 146480-35-5; 72-kDa gelatinase; matrix metalloproteinase 2; type IV collagenase (ambiguous); 3/4 collagenase (obsolete); matrix metalloproteinase 5 (obsolete); 72 kDa gelatinase type A; collagenase IV (ambiguous); collagenase type IV (ambiguous); MMP 2; type IV collagen metalloproteinase (ambiguous); type IV collagenase/gelatinase (ambiguous). Cat No: EXWM-4305.
gelatinase B
Similar to gelatinase A, but possesses a further domain. In peptidase family M10 (interstitial collagenase family). Group: Enzymes. Synonyms: 92-kDa gelatinase; matrix metalloproteinase 9; type V collagenase; 92-kDa type IV collagenase; macrophage gelatinase; 95 kDa type IV collagenase/gelatinase; collagenase IV (ambiguous); collagenase type IV (ambiguous); gelatinase MMP 9; MMP 9; type IV collagen metalloproteinase (ambiguous). Enzyme Commission Number: EC 3.4.24.35. CAS No. 146480-36-6. Matrix Metalloproteinase. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4317; gelatinase B; EC 3.4.24.35; 146480-36-6; 92-kDa gelatinase; matrix metalloproteinase 9; type V collagenase; 92-kDa type IV collagenase; macrophage gelatinase; 95 kDa type IV collagenase/gelatinase; collagenase IV (ambiguous); collagenase type IV (ambiguous); gelatinase MMP 9; MMP 9; type IV collagen metalloproteinase (ambiguous). Cat No: EXWM-4317.
Gelatin (Bovine)
Gelatin is a hydrophilic chemical useful in histochemistry, bacterial culture media and light microscope autoradiography. Group: Biochemicals. Grades: Highly Purified. CAS No. 9000-70-8. Pack Sizes: 5g, 25g. Molecular Formula: NA, Molecular Weight: US Biological Life Sciences.
Worldwide
Gelatine
Gelatine. CAS No. 9000-70-8. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Gelatin from bovine skin
Gelatin from bovine skin. CAS No. 9000-70-8.
Gelatin from cold water fish skin
Gelatin from cold water fish skin. CAS No. 9000-70-8.
Gelatin from porcine skin
Gelatin from porcine skin. CAS No. 9000-70-8.
Gelatin methacryloyl
The polymer product is a polymer that is derived from natural sources, with or without chemical modification. Alternative Names: GelMa, Gelatin Methacrylate, Gelatin methacrylamide. Molecular formula: (C40H59N11O13)n.
Gelatin Methacryloyl, 30% methacrylation, blue fluorescent
Gelatin Methacryloyl, 30% methacrylation, blue fluorescent. Uses: For analytical and research use. Alternative Names: GelMA, 30% methacrylation, blue fluorescent. Catalog: APB12506.
Gelatin Methacryloyl, 90% methacrylation, blue fluorescent
Gelatin Methacryloyl, 90% methacrylation, blue fluorescent. Uses: For analytical and research use. Alternative Names: GelMA, 90% methacrylation, blue fluorescent. Catalog: APB12493.
100g Pack Size. Group: Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C31H27NO4. CAS No. 9000-70-8. Prepack ID 20930194-100g. Molecular Weight 477.55. See USA prepack pricing.
Gelatin powdered, pure, from bovine skin, Ph.Eur,USP
100g Pack Size. Group: Amino Acids, Analytical Reagents, Biochemicals, Diagnostic Raw Materials. Formula: C31H27NO4. CAS No. 9000-70-8. Prepack ID 90005605-100g. Molecular Weight 477.55. See USA prepack pricing.
Gelatins
Gelatins is a non-toxic, non carcinogenic, biodegradable, and non irritating natural polymer derived from partial hydrolysis of collagen. Due to its strong liquid absorption and swelling ability, Gelatins has excellent hemostatic properties and can be used as a matrix material for the reduction, growth, and stability of metal nanoparticles. Gelatins can also be used for tumor cell culture and tumor therapy[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 9000-70-8. Pack Sizes: 50 mg; 100 mg; 500 mg. Product ID: HY-Y1365.
Gelatin, suitable for photographic applications, gel strength ~260 g Bloom
Gelatin, suitable for photographic applications, gel strength ~260 g Bloom. CAS No. 9000-70-8.
Geldanamycin
10mg Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C29H40N2O9. CAS No. 30562-34-6. Prepack ID 48834712-10mg. Molecular Weight 560.64. See USA prepack pricing.
Geldanamycin
Geldanamycin is a benzoquinone ansamycin antibiotic that inhibits heat shock protein 90 (HSP90). Geldanamycin has been shown to promote survival of neural stem cells from oxidative stress via inhibition of HSP90. It displays potent antineoplastic properties and inhibits myeloma cell growth. Uses: Antibiotics, antineoplastic. Synonyms: geldanomycin; NSC 122750; [(3R,5S,6R,7S,8E,10S,11S,12Z,14E)-6-hydroxy-5,11,21-trimethoxy-3,7,9,15-tetramethyl-16,20,22-trioxo-17-azabicyclo[16.3.1]docosa-1(21),8,12,14,18-pentaen-10-yl] carbamate. Grade: >98%. CAS No. 30562-34-6. Molecular formula: C29H40N2O9. Mole weight: 560.64.
Geldanamycin
Geldanamycin is a Hsp90 inhibitor with antimicrobial activity against many Gram-positive and some Gram-negative bacteria. Geldanamycin has anti-influenza virus H5N1 activities. Uses: Scientific research. Category: Signaling pathways. CAS No. 30562-34-6. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15230.
Geldanamycin-FITC
Geldanamycin-FITC, a Geldanamycin fluorescent probe, can be used in a fluorescence polarization assay for HSP90 inhibitors. Geldanamycin-FITC also can be used for detection of cell surface HSP90 (Ex/Em = 488/515 nm)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2969156-01-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-133705.
Gel Dye
Gel Dye. Gel dye is a sensitive, stable and relatively safe fluorescent nucleic acid dye designed to replace the highly toxic ethidium bromide (etbr) for staining dsdna, ssdna or rna in agarose gels or polyacrylamide gels. the sensitivity of gel dye is much higher than eb, and destaining is not required. gel ye and eb have virtually the same spectral properties. Group: Markers & Ladders. Storage: Store at -20 ?. Cat No: MK-2003.
Gellan gum
Gellan gum is a water-soluble polysaccharide produced by the bacterium Sphingomonas elodea. Gellan gum is composed of repeating units of tetrasaccharide, specifically glucose, rhamnose, and glucuronic acid. It is widely used as a gelling agent, thickener, and stabilizer in various food, pharmaceutical, and industrial applications due to its ability to form gels and its versatility in different conditions. Synonyms: Bistop MN-HM; Gel-Gro; Gellan; Gelrite; Gelrite gellan gum; Gelup K-S (F); Gelzan; Gelzan CM; Grindsted Gellan DAI 90; Kelcogel; Kelcogel 700; Kelcogel AF; Kelcogel AFT; Kelcogel CG; Kelcogel CG-LA; Kelcogel DGA; Kelcogel HF-B; Kelcogel Hi-pHive; Kelcogel HMB; Kelcogel HP-T; Kelcogel HT-P; Kelcogel hydriodide-pHive; Kelcogel PS; LT 100 (stabilizer); Neosoft J; Neosoft J 40; Newgelin LG-10; OMY; Phytagel; PS 60; Roeper 700f; Takaragen FE 01; TayaGel. CAS No. 71010-52-1.
Gellan gum
Gellan gum. Alternative Names: Gum, gellan. CAS No. 71010-52-1. Product ID: ACM71010521-9. Alfa Chemistry - ISO 9001:32057 Certified.
Gellan Gum
Gellan Gum. Group: Food ingredients. Pack Sizes: 25 Kg Drums.
Gellan Gum
Gellan Gum. CAS No. 71010-52-1.
Gellan Gum
Gellan Gum. CAS No. 71010-52-1. Cenik is your partner of choice for specialised chemicals. We don't just provide products - we supply solutions to your technical and regulatory specifications.
Gellan gum, for cell culture
Gellan gum is a linear microbial exopolysaccharide that can be used as a cell scaffold for both soft tissue and load bearing applications. Gellan gum has many advantages such as biocompatibility, biodegradability, nontoxic in nature, and physical stability in the presence of cations[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Agar substitute gelling agent, for cell culture. CAS No. 71010-52-1. Pack Sizes: 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-125870.
gellan lyase
The enzyme is highly specific to gellan, especially deacetylated gellan. Group: Enzymes. Enzyme Commission Number: EC 4.2.2.25. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5101; gellan lyase; EC 4.2.2.25. Cat No: EXWM-5101.
The enzyme releases 4-deoxy-4(5)-unsaturated D-glucuronic acid from oligosaccharides produced by polysaccharide lyases, e.g. the tetrasaccharide β-D-4-deoxy-Δ4-GlcAp-(1?4)-β-D-Glcp-(1?4)-α-L-Rhap-(1?3)-β-D-Glcp produced by EC 4.2.2.25, gellan lyase. The enzyme can also hydrolyse unsaturated chondroitin and hyaluronate disaccharides (β-D-4-deoxy-Δ4-GlcAp-(1?3)-β-D-GalNAc, β-D-4-deoxy-Δ4-GlcAp-(1?3)-β-D-GalNAc6S, β-D-4-deoxy-Δ4-GlcAp2S-(1?3)-β-D-GalNAc, β-D-4-deoxy-Δ4-GlcAp-(1?3)-β-D-GlcNAc), preferring the unsulfated disaccharides to the sulfated disaccharides. Group: Enzymes. Synonyms: UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Enzyme Commission Number: EC 3.2.1.179. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3862; gellan tetrasaccharide unsaturated glucuronyl hydrolase; EC 3.2.1.179; UGL (ambiguous); unsaturated glucuronyl hydrolase (ambiguous). Cat No: EXWM-3862.
GelMA, 30% methacrylation, Green Fluorescent
GelMA, 30% methacrylation, Green Fluorescent. Uses: For analytical and research use. Alternative Names: Gelatin Methacryloyl, 30% methacrylation, Green Fluorescent. Catalog: APB12504.
GelMA, 30% methacrylation, Red Fluorescent
GelMA, 30% methacrylation, Red Fluorescent. Uses: For analytical and research use. Alternative Names: Gelatin Methacryloyl, 30% methacrylation, Red Fluorescent. Catalog: APB12505.
GelMA, 60% methacrylation
GelMA (Gelatin Methacryloyl), 60% methacrylation, is a derivative obtained by the reaction of Methacrylic anhydride (MA) (HY-W017330) and gelatin. GelMA exhibits excellent biocompatibility, biodegradability, and moldability. GelMA can be photocrosslinked into hydrogels and can be used for research in regeneration of tissues, such as skin, tendon, bone, cartilage, blood vessel, and cardiovascular system. GelMA hydrogel also can be used for research on drug delivery, organ-on-a-chip, and biosensing[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gelatin Methacryloyl, 60% methacrylation. CAS No. 2280018-77-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W763582A.
GelMA, 60% methacrylation, Green Fluorescent
GelMA, 60% methacrylation, Green Fluorescent. Uses: For analytical and research use. Alternative Names: Gelatin Methacryloyl, 60% methacrylation, Green Fluorescent. Catalog: APB12498.
GelMA, 60% methacrylation, red fluorescent
GelMA, 60% methacrylation, red fluorescent. Uses: For analytical and research use. Alternative Names: Gelatin Methacryloyl, 60% methacrylation, red fluorescent. Catalog: APB12492.
GelMA, 90% methacrylation
GelMA (Gelatin Methacryloyl), 90% methacrylation, is a derivative obtained by the reaction of Methacrylic anhydride (MA) (HY-W017330) and gelatin. GelMA exhibits excellent biocompatibility, biodegradability, and moldability. GelMA can be photocrosslinked into hydrogels and can be used for research in regeneration of tissues, such as skin, tendon, bone, cartilage, blood vessel, and cardiovascular system. GelMA hydrogel also can be used for research on drug delivery, organ-on-a-chip, and biosensing[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gelatin Methacryloyl, 90% methacrylation. CAS No. 2280018-77-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W763582B.
GelMA, 90% methacrylation, Green Fluorescent
GelMA, 90% methacrylation, Green Fluorescent. Uses: For analytical and research use. Alternative Names: Gelatin Methacryloyl, 90% methacrylation, Green Fluorescent. Catalog: APB12491.
Gelomulide A
Gelomulide A is isolated from Suregada. Synonyms: (3β,5β,9β,10α,12β,14β)-16-Oxo-8,14:12,16-diepoxyabiet-13(15)-en-3-yl acetate. Grade: 98%. CAS No. 122537-59-1. Molecular formula: C22H30O5. Mole weight: 374.471.
Gelomulide B
Gelomulide B is a diterpenoid found in Suregada multiflora. Synonyms: (3S,4aS,6aS,7aR,10aS,11aS,11bR,11cR)-4,4,8,11c-tetramethyl-9-oxo-1,2,3,4,4a,5,6,7a,9,11a,11b,11c-dodecahydrobis(oxireno)[2',3':1,10a; 2'',3'':3,4]phenanthro[3,2-b]furan-3-yl acetate. Grade: 97.5%. CAS No. 122537-60-4. Molecular formula: C22H28O6. Mole weight: 388.454.
Gelomulide N
Gelomulide N also called 1alpha,3beta-Diacetoxy-8beta,14beta-epoxy-ent-abiet-13(15)-en-16,12-olide, is a natural diterpenoid compound. Synonyms: 1alpha,3beta-Diacetoxy-8beta,14beta-epoxy-ent-abiet-13(15)-en-16,12-olide; 1-epi-Gelomulide O. Grade: >97%. CAS No. 1005212-02-1. Molecular formula: C24H32O7. Mole weight: 432.51.
Gelsemine
Gelsemine. Group: Biochemicals. Grades: Plant Grade. CAS No. 509-15-9. Pack Sizes: 10mg. Molecular Formula: C20H22N2O2, Molecular Weight: 322.4. US Biological Life Sciences.
Worldwide
Gelsemine
Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects. Uses: Scientific research. Category: Natural products. CAS No. 509-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0388.
Gelsevirine, isolated from the herbs of Gelsemium elegans, could be developed as the treatment of anxiety-related disorders in human patients. Their anxiolytic mechanism may be involved in the agonist action of glycine receptor in the brain. Uses: Anxiolytic. Synonyms: Gelsemine, 1-methoxy-; 1-Methoxygelsemine. Grade: >98%. CAS No. 38990-03-3. Molecular formula: C21H24N2O3. Mole weight: 352.4.
Gelucire 44/14
Gelucire 44/14 is a potential and safe absorption enhancer for improving the absorption of poorly absorbable agents including insulin and calcitonin by pulmonary delivery. Uses: Scientific research. Category: Signaling pathways. CAS No. 121548-04-7. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-Y1892.
GEM144
GEM144 is a potent and orally active DNA polymerase α (POLA1) and HDAC 11 dual inhibitor. GEM144 induces acetylation of p53, activation of p21, G1/S cell cycle arrest, and apoptosis. GEM144 has significant antitumor activity in human orthotopic malignant pleural mesothelioma xenografts[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2487526-28-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143411.
GEM-5
GEM-5, a gemcitabine-based conjugate incorporating a HIF-1α inhibitor (YC-1) (IC 50 =30 nM), notably suppresses HIF-1α expression while enhancing tumor suppressor p53 expression. It induces apoptosis in A2780 cells and curbs tumor growth. Category: Active pharmaceutical ingredients. CAS No. 2233543-49-0. Product ID: API2233543490. Molecular formula: C32H29F2N5O8. Mole weight: 649.6.
Gem-C12
Gem-C12 is a prodrug of Gemcitabine (HY-17026). Gem-C12 terminates DNA chain elongation, inhibits nucleic acid synthesis and induces Apoptosis. Gem-C12 inhibits the proliferation of glioma cells. Gem-C12 and Honokiol (HY-N0003) exhibit synergistic anti-glioblastoma activity. Gem-C12 can be used in research related to glioblastoma multiforme[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 849139-19-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-185323.
Gemcabene
Gemcabene is an orally available lipid-lowering small molecule designed to target known lipid metabolic pathways, as an adjunctive therapy to reduce LDL-C, hsCRP and triglycerides (TGs). Currentl, Gemcabene is under Phase-II clinical trials in Hypertriglyceridaemia in USA. Synonyms: 6-(5-carboxy-5-methyl-hexoxy)-2,2-dimethyl-hexanoic acid; gemcabene; 6,6'-oxybis(2,2-dimethylhexanoic acid); PD72953; PD 72953; PD-72953. Grade: >98%. CAS No. 183293-82-5. Molecular formula: C16H30O5. Mole weight: 302.41.
Gemcadiol
Gemcadiol is a new antilipemic drug with lipid-regulating properties. Uses: Antilipemic. Synonyms: CI-720; CI 720; CI720; 2,2,9,9-Tetramethyl-1,10-decanediol. Grade: ≥98%. CAS No. 35449-36-6. Molecular formula: C14H30O2. Mole weight: 230.389.
Gemcitabine
Gemcitabine is a nucleoside analogue used in chemotherapy. It treats cancers including testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer and bladder cancer. Synonyms: 2'-Deoxy-2',2'-difluorocytidine; 2'-Deoxy-2',2'-difluoro-D-cytidine; 2',2'-Difluoro-2'-deoxycytidine; 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2',2'-Difluorodeoxycytidine; DDFC; DFdC; Folfugem; GemLip; Gemcel; NSC 613327; Gemzar. Grade: ≥95%. CAS No. 95058-81-4. Molecular formula: C9H11F2N3O4. Mole weight: 263.20.
Gemcitabine
Gemcitabine (LY 188011) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, and can modulate autophagy. Gemcitabine induces apoptosis through the activation of p38 MAPK. Gemcitabine demonstrates efficacy in mouse models of pancreatic and breast cancer. Gemcitabine can be used for cancer research, such as pancreatic cancer, non-small cell lung cancer, and breast cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 188011. CAS No. 95058-81-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-17026.
Gemcitabine
Gemcitabine, a nucleic acid synthesis inhibitor, is a very potent and specific deoxycytidine analogue, used as chemotherapy. Gemcitabine induces a potent p53-dependent apoptosis. Group: Inhibitors. Alternative Names: LY-188011, NSC 613327. CAS No. 95058-81-4. Pack Sizes: 50mg. Product ID: S1714. Formula: C9H11F2N3O4. Smiles: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F. Storage Conditions: powder, 4°C,3 years (in the dark) ; in solvent, -80°C,1 year (in the dark).
United States; Europe
Gemcitabine
Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis. Category: Active pharmaceutical ingredients. CAS No. 95058-81-4. Product ID: API95058814. Molecular formula: C9H11F2N3O4. Mole weight: 263.2.
Gemcitabine-13C,15N2
antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 188011-13C,15N2. CAS No. 1233921-74-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-17026S.