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Gemcitabine Impurity 4. Uses: For analytical and research use. Alternative Names: ((2R,3R,5R)-3-(benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate. CAS No. 134877-42-2. Molecular formula: C20H18F2O8S. Mole weight: 456.41. Catalog: APB134877422.
Gemcitabine Impurity 4. Uses: For analytical and research use. CAS No. 95058-77-8. Molecular formula: C5H6F2O4. Mole weight: 168.1. Catalog: APB95058778.
Gemcitabine Impurity 5
Gemcitabine Impurity 5. Uses: For analytical and research use. CAS No. 122111-12-0. Molecular formula: C5H6F2O4. Mole weight: 168.1. Catalog: APB122111120.
Gemcitabine Impurity 5
Gemcitabine Impurity 5. Uses: For analytical and research use. Alternative Names: ((2R,3R,5S)-3-(benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate. CAS No. 134877-43-3. Molecular formula: C20H18F2O8S. Mole weight: 456.41. Catalog: APB134877433.
Gemcitabine Impurity 6
Gemcitabine Impurity 6. Uses: For analytical and research use. CAS No. 122111-02-8. Molecular formula: C19H14F2O6. Mole weight: 376.31. Catalog: APB122111028.
Gemcitabine Impurity 7
Gemcitabine Impurity 7. Uses: For analytical and research use. CAS No. 122111-07-3. Molecular formula: C12H10F2O5. Mole weight: 272.2. Catalog: APB122111073.
Gemcitabine Impurity 7
Gemcitabine Impurity 7. Uses: For analytical and research use. Alternative Names: (2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4,4-difluorotetrahydrofuran-3-yl benzoate. CAS No. 134790-39-9. Molecular formula: C23H19F2N3O6. Mole weight: 471.41. Catalog: APB134790399.
Gemcitabine Impurity 8
Gemcitabine Impurity 8. Uses: For analytical and research use. Alternative Names: (2R,3R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4,4-difluorotetrahydrofuran-3-yl benzoate. CAS No. 134790-40-2. Molecular formula: C23H19F2N3O6. Mole weight: 471.41. Catalog: APB134790402.
Gemcitabine Impurity 8
Gemcitabine Impurity 8. Uses: For analytical and research use. CAS No. 143234-91-7. Molecular formula: C14H16F2O6. Mole weight: 318.27. Catalog: APB143234917.
Gemcitabine Impurity 9
Gemcitabine Impurity 9. Uses: For analytical and research use. CAS No. 866473-31-6. Molecular formula: C19H16F2O7. Mole weight: 394.33. Catalog: APB866473316.
Gemcitabine monophosphate
Gemcitabine monophosphate (Gemcitabine 5-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gemcitabine 5-phosphate. CAS No. 116371-67-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108932.
Gemcitabine monophosphate
R306465 is a novel HDAC inhibitor with broad-spectrum antitumor activity against solid (IC50: 30 to 300 nM) and hematological malignancies. R306465 was found to be a potent inhibitor of HDAC1 and -8 (class I) in vitro. Category: Active pharmaceutical ingredients. Synonyms: GemMP, Gemcitabine 5-phosphate. CAS No. 116371-67-6. Product ID: API116371676. Molecular formula: C9H12F2N3O7P. Mole weight: 343.18.
Gemcitabine Monophosphate
A monophosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as a cytotoxic agent and induce apoptosis. Synonyms: 2',2'-difluorodeoxycytidine Monophosphate; Gemcitabine 5'-phosphate. Grade: ≥ 95 % by HPLC. CAS No. 116371-67-6. Molecular formula: C9H12F2N3O7P. Mole weight: 343.18.
Gemcitabine Monophosphate-13C,15N2 Formate Salt
Gemcitabine Monophosphate-13C,15N2 Formate Salt. Group: Biochemicals. Alternative Names: 2'-Deoxy-2',2'-difluoro-5'-cytidylic Acid-13C,15N2 Formate. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C913CH14F2N15N2O9P, Molecular Weight: 392.18. US Biological Life Sciences.
Worldwide
Gemcitabine monophosphate disodium salt
Gemcitabine monophosphate disodium salt is a derivative of gemcitabine. Gemcitabine, under the trade name Gemzar, is a chemotherapy drug for the treatment of various cancers. Gemcitabine is used as a first-line medication for pancreatic cancer. Synonyms: Gemcitabine monophosphate disodium salt monohydrate; Gemcitabine monophosphate disodium; GemMP. CAS No. 1638288-31-9. Molecular formula: C9H12F2N3Na2O8P. Mole weight: 405.158.
Gemcitabine Monophosphate, Formate salt
Gemcitabine derivative. An antineoplastic agent. Group: Biochemicals. Alternative Names: 2'-Deoxy-2',2'-difluoro-5'-cytidylic acid formate. Grades: Highly Purified. CAS No. 116371-67-6. Pack Sizes: 5mg, 10mg, 25mg. US Biological Life Sciences.
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Gemcitabine-O-Si(di-iso)-O-Mc
Gemcitabine-O-Si(di-iso)-O-Mc is a agent-linker conjugate for ADC with potent antitumor activity by using Gemcitabine (a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent; HY-17026), linked via the ADC linker[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3109709-80-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-130812.
Gemcitabine (Standard)
Gemcitabine (Standard) is the analytical standard of Gemcitabine. This product is intended for research and analytical applications. Gemcitabine (LY 188011) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 188011 (Standard). CAS No. 95058-81-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-17026R.
Gemcitabine triphosphate
Gemcitabine triphosphate (dFdCTP), alongside its counterpart, the active diphosphate (dFdCDP), represents one of the two primary nucleoside metabolites of Gemcitabine within cellular structures. Category: Active pharmaceutical ingredients. CAS No. 110988-86-8. Product ID: API110988868. Molecular formula: C9H14F2N3O13P3. Mole weight: 503.14.
Gemcitabine Triphosphate
Gemcitabine Triphosphate is a compelling antineoplastic compound, holding immense potential in studying a multitude of cancers such as non-small cell lung cancer, pancreatic cancer and ovarian cancer. Its innovative mechanism inhibits DNA synthesand repair, thus effectively hindering the growth and propagation of malignant cells. Synonyms: 2',2'-Difluorodeoxycytidine 5'-triphosphate; dFdCTP. CAS No. 110988-86-8. Molecular formula: C9H14F2N3O13P3. Mole weight: 503.14.
Gemcitabine Triphosphate Ditriethylamine
Gemcitabine Triphosphate is a Gemcitabine phosphorylated metabolite, an antineoplastic agent. Synonyms: Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2',2'-difluoro-, compd. with N,N-diethylethanamine (1:2); 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) Di(N,N-diethylethanamine); Gemcitabine Triphosphate di(triethylamine) Salt. Grade: 97%. Molecular formula: C21H44F2N5O13P2. Mole weight: 705.52.
Gemcitabine Triphosphate Ditriethylamine
Gemcitabine Triphosphate is a phosphorylated metabolite of Gemcitabine , an antineoplastic agent. Group: Biochemicals. Alternative Names: 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) Di(N,N-diethylethanamine). Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemcitabine Triphosphate (triethylammonium salt form)
An impurity of Gemcitabine. Gemcitabine is an antineoplastic chemotherapy medication of the antimetabolites class. It halts cell division through damaging RNA or DNA which control the process. It can be used to treat multiple cancers. Synonyms: Cytidine 5'-(tetrahydrogen triphosphate), 2'-deoxy-2',2'-difluoro-, compd. with N,N-diethylethanamine (1:3); 2'-Deoxy-2',2'-difluorocytidine 5'-(Tetrahydrogen Triphosphate) triethylammonium; Gemcitabine Triphosphate Tri(triethylamine) Salt. Grade: 95%. CAS No. 1035495-84-1. Molecular formula: C9H14F2N3O13P3.3C6H15N. Mole weight: 806.71.
Gemfibrozil
Gemfibrozil is the generic name for an oral drug used to lower lipid levels. It belongs to a group of drugs known as fibrates. It is most commonly sold as the brand name, Lopid. Other brand names include Jezil and Gen-Fibro. Synonyms: CI-719; CI 719; CI719. Grade: >98%. CAS No. 25812-30-0. Molecular formula: C15H22O3. Mole weight: 250.33.
Gemfibrozil
Gemfibrozil is an activator of PPAR-α, used as a lipid-lowering agent; Gemfibrozil is also a nonselective inhibitor of several P450 isoforms, with Ki values for CYP2C9, 2C19, 2C8, and 1A2 of 5.8, 24, 69, and 82 μM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CI-719. CAS No. 25812-30-0. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg. Product ID: HY-B0258.
Gemfibrozil
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C15H22O3. CAS No. 25812-30-0. Prepack ID 48653561-5g. Molecular Weight 250.33. See USA prepack pricing.
Gemfibrozil 1-O-β-glucuronide
Gemfibrozil 1-O-β-Glucuronide, a metabolite of Gemfibrozil (CI-719; HY-B0258), is a potent and competitive P450 (CYP) isoform CYP2C8 inhibitor with an IC50 of 4.07 μM[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 91683-38-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-129993.
Gemfibrozil 1-O-b-Glucuronide
The major metabolite of Gemfibrozil. Group: Biochemicals. Alternative Names: 1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] β-D-Glucopyranuroic Acid; Gemfibrozil Glucuronide. Grades: Highly Purified. CAS No. 91683-38-4. Pack Sizes: 500ug, 1mg. Molecular Formula: C21H30O9, Molecular Weight: 426.46. US Biological Life Sciences.
The major labeled metabolite of Gemfibrozil. Group: Biochemicals. Alternative Names: 1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] b-D-Glucopyranuroic Acid-d6;Gemfibrozil Glucuronide. Grades: Highly Purified. Pack Sizes: 500ug. US Biological Life Sciences.
A serum lipid regulating agent used as an antihyperlipoproteinem ic. Group: Biochemicals. Alternative Names: 5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoic Acid, CI-719, Decrelip, Genlip, Gevilon, Lipozid, Lpur, Lopid. Grades: Highly Purified. Pack Sizes: 1g. US Biological Life Sciences.
Worldwide
Gemfibrozil Acyl-beta-D-Glucuronide
Gemfibrozil Acyl-beta-D-Glucuronide is the major metabolite of Gemfibrozil. It can be oxidized to a benzyl radical intermediate which binds to the γ-meso position of heme. Synonyms: 1-[5-(2,5-Dimethylphenoxy)-2-dimethylpentanoate] b-D-glucopyranuronic acid. Grade: > 95%. CAS No. 91683-38-4. Molecular formula: C21H30O9. Mole weight: 426.47.
Gemfibrozil b-D-glucuronide-[d6]
Gemfibrozil b-D-glucuronide-[d6] is a remarkable compound of immense significance, finding its purpose in the therapeutic research of cardiovascular disorders. Specifically tailored to study the levels of cholesterol and triglycerides, this compound manifests its influence as a distinguished PPAR-alpha agonist. Synonyms: 1-[5-(2,5-Dimethylphenoxy)-2,2-dimethylpentanoate] b-D-glucopyranuronic acid; Gemfibrozil b-D-glucuronide-D6. Molecular formula: C21H24D6O9. Mole weight: 432.49.
Gemfibrozil-[d6]
Gemfibrozil-[d6] is an isotopically labelled analog of Gemfibrozil. Gemfibrozil is a medication used to treat abnormal blood lipid levels. Synonyms: gemfibrozil (2,2-dimethyl-d6). Grade: 98% by CP; 98% atom D. CAS No. 1184986-45-5. Molecular formula: C15H16D6O3. Mole weight: 256.4.
Gemfibrozil-d6 1-O- β-D-Glucuronide Benzyl Ester
A labelled Gemfibrozil (G305750) glucuronide derivative. Group: Biochemicals. Alternative Names: 1-[5-(2,5-Di(methyl-d3)phenoxy)-2,2-dimethylpentanoate] β-D-Glucopyranuroic Acid Benzyl Ester; Gemfibrozil-d6 Glucuronide Benzyl Ester. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
An isotopically labeled analog of a serum lipid regulating agent used as an antihyperlipoproteinem ic. Group: Biochemicals. Alternative Names: 5-(2,5-Dimethylphenoxy)-2,2-dimethyl-(d6)-pentanoic Acid. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemfibrozil EP impurity B
Gemfibrozil EP impurity B. Uses: For analytical and research use. CAS No. 114413-97-7. Molecular formula: C15H23NO2. Mole weight: 249.35. Catalog: APB114413977.
Gemfibrozil EP impurity C
Gemfibrozil EP impurity C. Uses: For analytical and research use. Molecular formula: C15H24O3. Mole weight: 252.35. Catalog: APB11789.
Gemfibrozil EP impurity D
Gemfibrozil EP impurity D. Uses: For analytical and research use. CAS No. 1798429-95-4. Molecular formula: C18H26O3. Mole weight: 290.4. Catalog: APB1798429954.
Gemfibrozil EP impurity E
Gemfibrozil EP impurity E. Uses: For analytical and research use. CAS No. 500904-61-0. Molecular formula: C18H26O3. Mole weight: 290.4. Catalog: APB500904610.
Gemfibrozil EP impurity F
Gemfibrozil EP impurity F. Uses: For analytical and research use. CAS No. 500904-64-3. Molecular formula: C18H22O. Mole weight: 254.37. Catalog: APB500904643.
Gemfibrozil EP impurity G
Gemfibrozil EP impurity G. Uses: For analytical and research use. CAS No. 3727-20-6. Molecular formula: C11H14O. Mole weight: 162.23. Catalog: APB3727206.
Gemfibrozil EP impurity H
Gemfibrozil EP impurity H. Uses: For analytical and research use. CAS No. 415724-02-6. Molecular formula: C19H24O2. Mole weight: 284.4. Catalog: APB415724026.
Gemfibrozil EP impurity I
Gemfibrozil EP impurity I. Uses: For analytical and research use. CAS No. 149105-25-9. Molecular formula: C16H24O3. Mole weight: 264.37. Catalog: APB149105259.
Gemfibrozil EP Impurity I
An impurity of Gemfibrozil. Gemfibrozil is a fibrate lipid-regulating agent used primarily to treat hypertriglyceridemia and reduce the risk of cardiovascular events. Synonyms: Gemfibrozil methyl ester; Pentanoic acid, 5-(2,5-dimethylphenoxy)-2,2-dimethyl-, methyl ester; Gemfibrozil impurity I [EP]; Gemfibrozil Impurity I; 5-(2,5-Dimethylphenoxy)-2,2-dimethyl-pentanoic acid methyl ester. CAS No. 149105-25-9. Molecular formula: C16H24O3. Mole weight: 264.36.
Gemfibrozil impurity 1
Gemfibrozil impurity 1. Uses: For analytical and research use. CAS No. 63258-18-4. Molecular formula: C17H26O3. Mole weight: 278.39. Catalog: APB63258184.
Gemfibrozil impurity 2. Uses: For analytical and research use. CAS No. 154021-24-6. Molecular formula: C18H28O3. Mole weight: 292.42. Catalog: APB154021246.
Gemfibrozil impurity 3. Uses: For analytical and research use. CAS No. 91683-38-4. Molecular formula: C21H30O9. Mole weight: 426.46. Catalog: APB91683384.
Gemfibrozil Related Compound A is a derivative of Gemfibrozil. Synonyms: (E,Z)-2,2-dimethyl-5-[2,5-dimethyl-4-(propene-1-yl)phenoxy]valeric acid; 5-[2,5-Dimethyl-4-(1-propen-1-yl)phenoxy]-2,2-dimethylpentanoic acid; 4-(1-Propenyl) Gemfibrozil. Grade: > 95%. CAS No. 500904-61-0. Molecular formula: C18H26O3. Mole weight: 290.41.
Gemfibrozil Related Compound A
Gemfibrozil Related Compound A. Uses: For analytical and research use. CAS No. 500904-61-0. Mole weight: 290.40. Catalog: AP500904610.
Gemfibrozil Related Compound D
Gemfibrozil Related Compound D is a biomedical product used in the research of hyperlipidemia. It exhibits properties similar to Gemfibrozil, an FDA-approved drug. Synonyms: 6-Propenyl Gemfibrozil (Mixture of Z and E Isomers). Grade: > 95%. Molecular formula: C18H26O3. Mole weight: 290.41.
Gemifloxacin
Gemifloxacin is a fluoronaphthyridone with strong antibacterial effect. Category: Active pharmaceutical ingredients. Synonyms: SB-265805. CAS No. 175463-14-6. Product ID: API175463146. Molecular formula: C18H20FN5O4. Mole weight: 389.38.
Gemifloxacin-13C2,d2
Third generation fluorinated quinolone antibacterial. Group: Biochemicals. Alternative Names: 7-[3-(Aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic Acid-13C2,d2; SB-265805-13C2,d2; LB-20304-13C2,d2. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemifloxacin Impurity
Gemifloxacin Impurity is an Gemifloxacin impurity, Third generation fluorinated quinolone antibacterial. Synonyms: Desmethoxyamino Hydroxy Gemifloxacin; 7-(3-(Aminomethyl)-4-hydroxypyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic Acid. Grade: > 95%. CAS No. 213672-25-4. Molecular formula: C17H19FN4O4. Mole weight: 362.36.
Gemifloxacin mesilate
Gemifloxacin mesilate. Group: Biochemicals. Alternative Names: 7-[3-(Aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid mesilate; SB-265805 mesilate; LB-20304 mesilate. Grades: Highly Purified. CAS No. 210353-53-0. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C19H24FN5O7S. US Biological Life Sciences.
Worldwide
Gemifloxacin mesylate
Gemifloxacin mesylate, a fluoroquinolone, is an oral broad-spectrum antibacterial agent that has shown strong activity in vitro against a variety of respiratory tract pathogens for the treatment of mild to moderate pneumonia. Synonyms: 1,8-Naphthyridine-3-carboxylic acid, 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-, monomethanesulfonate; Factive; Floxguard; Gemixa; LB 20304a; SB 265805S; 7-[(4Z)-3-(aminomethyl)-4-(methoxyimino)-1-pyrrolidinyl]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-1,8-Naphthyridine-3-carboxylic Acid Monomethanesulfonate; (Z)-Gemifloxacin Mesilate. Grade: ≥95%. CAS No. 210353-53-0. Molecular formula: C19H24FN5O7S. Mole weight: 485.50.
Gemifloxacin mesylate
Gemifloxacin mesylate (Gemifloxacin mesylate) inhibits activities of DNA gyrase and topoisomerase IV, thereby inhibiting DNA replication and eventually bacterial growth. Gemifloxacin Mesylate is the mesylate salt form of gemifloxacin, a synthetic broad-spectrum fluoroquinolone with antibacterial activity. This fluoroquinolone exerts an enhanced spectrum of activity against gram-positive bacteria such as Streptococcus pneumonia and Staphylococcus aureus, in addition to its activity against gram-negative bacteria. Category: Active pharmaceutical ingredients. CAS No. 210353-53-0. Product ID: API210353530. Molecular formula: C19H24FN5O7S. Mole weight: 485.49.
Gemifloxacin mesylate
Gemifloxacin mesylate (SB-265805S; LB-20304a) is an orally active broad-spectrum quinolone antibacterial antibiotic. Gemifloxacin mesylate inhibits DNA synthesis by inhibiting DNA gyrase and Topoisomerase IV activities. Gemifloxacin mesylate has potent antibacterial activities against gram-positive bacteria in vitro efficacy study, particularly Streptococci and Staphylococci. Gemifloxacin mesylate has been used in the research of respiratory tract infections[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: SB-265805S; LB-20304a. CAS No. 210353-53-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1050.
Gemifloxacin Related Compound 1
Gemifloxacin Related Compound 1 is an impurity of Gemifloxacin, an antibiotic drug commonly used to treat respiratory tract infections, such as bronchitand pneumonia. Grade: > 95%. Molecular formula: C18H20FN5O4. Mole weight: 389.39.
Gemifloxacin Related Compound 2
Gemifloxacin Related Compound 2 is an impurity of gemifloxacin, a drug for treating an array of bacterial afflictions encompassing respiratory and urinary tract infections. Grade: > 95%. Molecular formula: C17H17FN4O4. Mole weight: 360.35.
Gemigliptin
Gemigliptin. Group: Biochemicals. Grades: Highly Purified. CAS No. 911637-19-9. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C18H19F8N5O2. US Biological Life Sciences.
Worldwide
Gemigliptin
Gemigliptin (LC15-0444) is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor(KD : 7.25 nM.). Category: Active pharmaceutical ingredients. CAS No. 911637-19-9. Product ID: API911637199. Molecular formula: C18H19F8N5O2. Mole weight: 489.36.
Gemigliptin
Gemigliptin is a potent dipeptidyl peptidase-4 (DPP-4) inhibitor with the potential use in diabetes treatment. Synonyms: 1-[(2S)-2-amino-4-[2,4-bis(trifluoromethyl)-6,8-dihydro-5H-pyrido[3,4-d]pyrimidin-7-yl]-4-oxobutyl]-5,5-difluoropiperidin-2-one. CAS No. 911637-19-9. Molecular formula: C18H19F8N5O2. Mole weight: 489.37.
Gemigliptin Tartrate
Gemigliptin Tartrate (LC15-0444 tartrate) is a highly selective, reversible and competitive inhibitor of dipeptidyl peptidase-4 (DPP-4). It has an IC50 of 10.3 nM for human recombinant DPP-4. Gemigliptin tartrate exhibits potent anti-glycation properties. Category: Active pharmaceutical ingredients. CAS No. 1374639-74-3. Product ID: API1374639743. Molecular formula: C22H25F8N5O8. Mole weight: 639.45.
Gemilukast
Gemilukast is an orally active and potent dual cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2) antagonist, with IC50s of 1.7, 25 nM for human CysLT1 and CysLT2, respectively. Gemilukast is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ONO-6950. CAS No. 1232861-58-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-16780.
Gemilukast
This active molecular is an potent dual Leukotriene CysLT1 and CysLT2 Receptor antagonist originated by Ono Pharmaceutical. IC50 values is 1.7nM against human CysLT1 and 25 nM against human CysLT2. Gemilukast reduced LTC4-induced bronchoconstriction in asthmatic animal models dose-dependently. In addition, it can also reduceantigen-induced constriction of isolated human bronchi. In 2015, Phase-II clinical trials in Asthma in Japan and USA was on-going. Uses: Asthma. Synonyms: ONO6950; ONO 6950; ONO-6950; 4,4'-(4-fluoro-7-((4-(4-(3-fluoro-2-methylphenyl)butoxy)phenyl)ethynyl)-2-methyl-1H-indole-1,3-diyl)dibutyric acid; 1232861-64-1 (disodium salt); 1232873-69-6 (8 hydrate and disodium salt). Grade: 98%. CAS No. 1232861-58-3. Molecular formula: C36H37F2NO5. Mole weight: 601.69.
Gemilukast 8 hydrate and disodium salt).
Gemilukast 8 hydrate and disodium salt is an exceptional compound harnessed to studying inflammatory ailments, such as asthma and allergic rhinitis. Synonyms: 1H-Indole-1,?3-dibutanoic acid, 4-fluoro-7-[2-[4-[4-(3-fluoro-2-methylphenyl)?butoxy]?phenyl]?ethynyl]?-2-methyl-, sodium salt, hydrate (1:2:8). Grade: 98%. CAS No. 1232873-69-6. Molecular formula: C36H37F2NO5.8H2O.2Na. Mole weight: 601.69.