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| Product | Description | |
|---|---|---|
| GDP-L-galactose sodium salt | GDP-L-galactose sodium salt, an indispensable element in the field of biomedicine, assumes a pivotal function in the amalgamation of Vitamin C, thereby facilitating the amelioration of scurvy and associated ailments. This efficacious product showcases its potential in enhancing general well-being and mitigating deficiencies stemming from insufficient levels of Vitamin C. Synonyms: Guanosine 5-diphosphate-L-galactose. Grade: 95%. CAS No. 6815-91-4. Molecular formula: C16H23N5Na2O16P2. Mole weight: 649.30. |  |
| GDP - lyophilized | Guanosine 5'-diphosphate could be used to study cell signaling related to G-coupled protein receptors as well as some GTPases. Synonyms: Guanosine-5'-diphosphate, Sodium salt. Grade: ≥ 90 % by HPLC. CAS No. 43139-22-6. Molecular formula: C10H15N5O11P2(free acid). Mole weight: 443.20 (free acid). | |
| GDP-Man:Man1GlcNAc2-PP-dolichol α-1,3-mannosyltransferase | The biosynthesis of asparagine-linked glycoproteins utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway. Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an α1,3-mannosylation of D-Man-β-(1?4)-D-GlcNAc-β-(1?4)-D-GlcNAc-diphosphodolichol, followed by an α1,6-mannosylation (cf. EC 2.4.1.257), to form the first branched pentasaccharide intermediate of the dolichol pathway. Group: Enzymes. Synonyms: Alg2 mannosyltransferase (ambiguous); ALG2 (gene name, ambiguous); glycolipid 3-α-mannosyltransferase; GDP-mannose:glycolipid 3-&alph. Enzyme Commission Number: EC 2.4.1.132. CAS No. 81181-76-2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2357; GDP-Man:Man1GlcNAc2-PP-dolichol α-1,3-mannosyltransferase; EC 2.4.1.132; 81181-76-2; Alg2 mannosyltransferase (ambiguous); ALG2 (gene name, ambiguous); glycolipid 3-α-mannosyltransferase; GDP-mannose:glycolipid 3-α-D-mannosyltransferase; GDP-Man:Man1GlcNAc2-PP-Dol α-1,3-mannosyltransferase; GDP-D-mannose:D-Man-β-(1?4)-D-GlcNAc-β-(1?4)-D-GlcNAc-diphosphodolichol 3-α-mannosyltransferase. Cat No: EXWM-2357. |  |
| GDP-Man:Man1GlcNAc2-PP-dolichol α-1,3-mannosyltransferase | The biosynthesis of asparagine-linked glycoproteins utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway. Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an α1,3-mannosylation of D-Man-β-(1→4)-D-GlcNAc-β-(1→4)-D-GlcNAc-diphosphodolichol, followed by an α1,6-mannosylation (cf. EC 2.4.1.257), to form the first branched pentasaccharide intermediate of the dolichol pathway. | |
| GDP-Man:Man2GlcNAc2-PP-dolichol α-1,6-mannosyltransferase | The biosynthesis of asparagine-linked glycoproteins utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway. Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an α1,3-mannosylation (cf. EC 2.4.1.132) of β-D-Man-(1?4)-β-D-GlcNAc-(1?4)-α-D-GlcNAc-diphosphodolichol, followed by an α1,6-mannosylation, to form the first branched pentasaccharide intermediate of the dolichol pathway. Group: Enzymes. Synonyms: GDP-Man:Man2GlcNAc2-PP-Dol α-1,6-mannosyltransferase; Alg2 mannosyltransferase (ambiguous); ALG2 (gene name, ambiguous); GDP-Man:Man1GlcNAc2-PP-dolichol mannosyltransfera. Enzyme Commission Number: EC 2.4.1.257. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2487; GDP-Man:Man2GlcNAc2-PP-dolichol α-1,6-mannosyltransferase; EC 2.4.1.257; GDP-Man:Man2GlcNAc2-PP-Dol α-1,6-mannosyltransferase; Alg2 mannosyltransferase (ambiguous); ALG2 (gene name, ambiguous); GDP-Man:Man1GlcNAc2-PP-dolichol mannosyltransferase (ambiguous); GDP-D-mannose:D-Man-α-(1?3)-D-Man-β-(1?4)-D-GlcNAc-β-(1?4)-D-GlcNAc-diphosphodolichol α-6-mannosyltransferase. Cat No: EXWM-2487. | |
| GDP-Man:Man2GlcNAc2-PP-dolichol α-1,6-mannosyltransferase | The biosynthesis of asparagine-linked glycoproteins utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway. Alg2 mannosyltransferase from Saccharomyces cerevisiae carries out an α1,3-mannosylation (cf. EC 2.4.1.132) of β-D-Man-(1→4)-β-D-GlcNAc-(1→4)-α-D-GlcNAc-diphosphodolichol, followed by an α1,6-mannosylation, to form the first branched pentasaccharide intermediate of the dolichol pathway. | |
| GDP-Man:Man3GlcNAc2-PP-dolichol α-1,2-mannosyltransferase | The biosynthesis of asparagine-linked glycoproteins (N-linked protein glycosylation) utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway. ALG11 mannosyltransferase from Saccharomyces cerevisiae carries out two sequential steps in the formation of the lipid-linked core oligosaccharide, adding two mannose residues in α(1→2) linkages to the nascent oligosaccharide. | |
| GDP-Man:Man3GlcNAc2-PP-dolichol α-1,2-mannosyltransferase | The biosynthesis of asparagine-linked glycoproteins (N-linked protein glycosylation) utilizes a dolichyl diphosphate-linked glycosyl donor, which is assembled by the series of membrane-bound glycosyltransferases that comprise the dolichol pathway. ALG11 mannosyltransferase from Saccharomyces cerevisiae carries out two sequential steps in the formation of the lipid-linked core oligosaccharide, adding two mannose residues in α(1?2) linkages to the nascent oligosaccharide. Group: Enzymes. Synonyms: ALG11; AL. Enzyme Commission Number: EC 2.4.1.131. CAS No. 74506-43-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2356; GDP-Man:Man3GlcNAc2-PP-dolichol α-1,2-mannosyltransferase; EC 2.4.1.131; 74506-43-7; ALG11; ALG11 mannosyltransferase; LEW3 (gene name); At2G40190 (gene name); gmd3 (gene name); galactomannan deficiency protein 3; GDP-mannose:glycolipid 1,2-α-D-mannosyltransferase; glycolipid 2-α-mannosyltransferase; GDP-mannose:glycolipid 2-α-D-mannosyltransferase; GDP-Man:Man3GlcNAc2-PP-Dol α-1,2-mannosyltransferase; GDP-α-D-mannose:D-Man-α-(1?3)-[D-Man-α-(1?6)]-D-Man-β-(1?4)-D-GlcNAc-β-(1?4)-D-GlcNAc-diphosphodolichol 2-α-D-mannosyltransferase. Cat No: EXWM-2356. | |
| GDP-mannose | GDP-mannose. Synonyms: Guanosine 5'-(trihydrogen diphosphate), P'-α-D-mannopyranosyl ester; Guanosine 5'-(trihydrogen pyrophosphate), mono-α-D-mannopyranosyl ester; Guanosine 5'-pyrophosphate, α-D-mannopyranosyl ester; GDP-D-mannose; GDP-α-D-mannose; Guanosine 5'-(trihydrogen pyrophosphate) mono-D-mannosyl ester; Guanosine 5'-(trihydrogen pyrophosphate) monomannopyranosyl ester; Guanosine 5'-diphosphate D-mannose; Guanosine 5'-pyrophosphate D-mannosyl ester; Guanosine 5'-pyrophosphate α-D-mannosyl ester; Guanosine diphosphate mannose; Guanosine diphosphomannose. Grade: ≥90%. CAS No. 3123-67-9. Molecular formula: C16H25N5O16P2. Mole weight: 605.34. | |
| GDP-mannose 3,5-epimerase | This enzyme belongs to the family of isomerases, specifically those racemases and epimerases acting on carbohydrates and derivatives. This enzyme participates in ascorbate and aldarate metabolism. Group: Enzymes. Synonyms: GDP-D-mannose:GDP-L-galactose epimerase; guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase. Enzyme Commission Number: EC 5.1.3.18. CAS No. 72162-82-4. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5403; GDP-mannose 3,5-epimerase; EC 5.1.3.18; 72162-82-4; GDP-D-mannose:GDP-L-galactose epimerase; guanosine 5'-diphosphate D-mannose:guanosine 5'-diphosphate L-galactose epimerase. Cat No: EXWM-5403. | |
| GDP-mannose 4,6-dehydratase | The bacterial enzyme requires bound NAD+. This enzyme forms the first step in the biosynthesis of GDP-α-D-rhamnose and GDP-β-L-fucose. In Aneurinibacillus thermoaerophilus L420-91T, this enzyme acts as a bifunctional enzyme, catalysing the above reaction as well as the reaction catalysed by EC 1.1.1.281, GDP-4-dehydro-6-deoxy-D-mannose reductase. Belongs to the short-chain dehydrogenase/reductase enzyme family, having homologous structures and a conserved catalytic triad of Lys, Tyr and Ser/Thr residues. Group: Enzymes. Synonyms: guanosine 5'-diphosphate-D-mannose oxidoreductase; guanosine diphosphomannose oxidoreductase; guanosine diphosphomannose 4,6-dehydratase; GDP-D-mannose dehydratase; GDP-D-mannose 4,6-dehydratase; Gmd; GDP-mannose 4,6-hydro-lyase; GDP-mannose 4,6-hydro-. Enzyme Commission Number: EC 4.2.1.47. CAS No. 37211-59-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5036; GDP-mannose 4,6-dehydratase; EC 4.2.1.47; 37211-59-9; guanosine 5'-diphosphate-D-mannose oxidoreductase; guanosine diphosphomannose oxidoreductase; guanosine diphosphomannose 4,6-dehydratase; GDP-D-mannose dehydratase; GDP-D-mannose 4,6-dehydratase; Gmd; GDP-mannose 4,6-hydro-lyase; GDP-mannose 4,6-hydro-lyase (GDP-4-dehydro-6-deoxy-D-mannose-forming). Cat No: EXWM-5036. | |
| GDP-mannose 6-dehydrogenase | Also acts on the corresponding deoxynucleoside diphosphate derivative as a substrate. Group: Enzymes. Synonyms: guanosine diphosphomannose dehydrogenase; GDP-mannose dehydrogenase; guanosine diphosphomannose dehydrogenase; guanosine diphospho-D-mannose dehydrogenase. Enzyme Commission Number: EC 1.1.1.132. CAS No. 37250-63-8. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-0036; GDP-mannose 6-dehydrogenase; EC 1.1.1.132; 37250-63-8; guanosine diphosphomannose dehydrogenase; GDP-mannose dehydrogenase; guanosine diphosphomannose dehydrogenase; guanosine diphospho-D-mannose dehydrogenase. Cat No: EXWM-0036. | |
| GDP-mannose:cellobiosyl-diphosphopolyprenol α-mannosyltransferase | In the bacterium Gluconacetobacter xylinus (previously known as Acetobacter xylinum) the enzyme is involved in the biosynthesis of the exopolysaccharide acetan. In Xanthomonas campestris the enzyme is involved in the biosynthesis of the exopolysaccharide xanthan. Group: Enzymes. Synonyms: GumH; AceA; α1,3-mannosyltransferase AceA. Enzyme Commission Number: EC 2.4.1.252. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2482; GDP-mannose:cellobiosyl-diphosphopolyprenol α-mannosyltransferase; EC 2.4.1.252; GumH; AceA; α1,3-mannosyltransferase AceA. Cat No: EXWM-2482. | |
| GDP-mannose:cellobiosyl-diphosphopolyprenol α-mannosyltransferase | In the bacterium Gluconacetobacter xylinus (previously known as Acetobacter xylinum) the enzyme is involved in the biosynthesis of the exopolysaccharide acetan. In Xanthomonas campestris the enzyme is involved in the biosynthesis of the exopolysaccharide xanthan. | |
| GDP-Mannose pyrophosphorylase from Pyrococcus furiosus, Recombinant | In enzymology, a mannose-1-phosphate guanylyltransferase (EC 2.7.7.13) is an enzyme that catalyzes the chemical reaction: GTP + alpha-D-mannose 1-phosphate ? diphosphate + GDP-mannose. Thus, the two substrates of this enzyme are GTP and alpha-D-mannose 1-phosphate, whereas its two products are diphosphate and GDP-mannose. Group: Enzymes. Synonyms: GTP-mannose-1-phosphate guanylyltransferase; PIM-GMP; GDP-mannose pyrophosphorylase; guanosine 5'-diphospho-D-mannose pyrophosphorylase; guanosine diphosphomannose pyrophosphorylase; guanosine triphosphate-mannose 1-phosphate guanylyltransferase; mannose 1-phosphate guanylyltransferase (guanosine triphosphate); mannose-1-phosphate guanylyltransferase; EC 2.7.7.13. Enzyme Commission Number: EC 2.7.7.13. CAS No. 37278-24-3. Purity: min 95% by SDS-PAGE. GDP-Mannose pyrophosphorylase. Source: E. coli. Species: Pyrococcus furiosus. GTP-mannose-1-phosphate guanylyltransferase; PIM-GMP; GDP-mannose pyrophosphorylase; guanosine 5'-diphospho-D-mannose pyrophosphorylase; guanosine diphosphomannose pyrophosphorylase; guanosine triphosphate-mannose 1-phosphate guanylyltransferase; mannose 1-phosphate guanylyltransferase (guanosine triphosphate); mannose-1-phosphate guanylyltransferase; EC 2.7.7.13. Cat No: NATE-1504. | |
| GDP-perosamine N-acetyltransferase | D-Perosamine is one of several dideoxy sugars found in the O-antigen component of the outer membrane lipopolysaccharides of Gram-negative bacteria. Group: Enzymes. Synonyms: perB (gene name); GDP-α-D-perosamine N-acetyltransferase. Enzyme Commission Number: EC 2.3.1.227. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2174; GDP-perosamine N-acetyltransferase; EC 2.3.1.227; perB (gene name); GDP-α-D-perosamine N-acetyltransferase. Cat No: EXWM-2174. | |
| GDP-perosamine synthase | A pyridoxal 5'-phosphate enzyme. D-Perosamine is one of several dideoxy sugars found in the O-specific polysaccharide of the lipopolysaccharide component of the outer membrane of Gram-negative bacteria. The enzyme catalyses the final step in GDP-α-D-perosamine synthesis. Group: Enzymes. Synonyms: RfbE; GDP-4-keto-6-deoxy-D-mannose-4-aminotransferase; GDP-perosamine synthetase; PerA; GDP-4-amino-4,6-dideoxy-α-D-mannose:2-oxoglutarate aminotransferase. Enzyme Commission Number: EC 2.6.1.102. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2842; GDP-perosamine synthase; EC 2.6.1.102; RfbE; GDP-4-keto-6-deoxy-D-mannose-4-aminotransferase; GDP-perosamine synthetase; PerA; GDP-4-amino-4,6-dideoxy-α-D-mannose:2-oxoglutarate aminotransferase. Cat No: EXWM-2842. | |
| GDP polyribonucleotidyltransferase | The enzyme from rhabdoviruses transfers 5'-monophosphorylated (p-)mRNA from 5'-triphosphorylated (ppp-)mRNA to GDP to form 5'-capped mRNA (GpppmRNA) in a viral mRNA-start sequence-dependent manner. The (p-)mRNA transfer reaction proceeds through a covalent enzyme-pmRNA intermediate. Group: Enzymes. Enzyme Commission Number: EC 2.7.7.88. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3301; GDP polyribonucleotidyltransferase; EC 2.7.7.88. Cat No: EXWM-3301. | |
| GE11 | GE11 is a active peptide and combines with colloidal drug delivery systems as smart carriers for antitumor drugs and can be used for cancer study[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 875142-25-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P10128. |  |
| GE11, Cys Conjugated | GE11, Cys Conjugated is a peptide conjugate. GE11, Cys Conjugated consists of GE11 (HY-P10128) conjugated to a GGGGC sequence. GE11, Cys Conjugated can be used to synthesize stimulus-responsive peptide nanomaterials (SRPNs) for photoacoustic imaging and cancer research, such as studies on triple-negative breast cancer (TNBC)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1259031-31-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-P11051. | |
| GE20372 A | GE20372 A, a tetrapeptide, is produced by the strain of Streptomyces sp. It is used as a human immunodeficiency virus (HIV-L) protease inhibitor. Synonyms: GE20372 Factor A; GE-20372A; (1(S),2(S))-N2-(((1-Carboxy-2-(4-hydroxyphenyl)ethyl)amino)carbonyl)-L-arginyl-N-(1-formyl-2-phenylethyl)-L-valinamide. CAS No. 163565-75-1. Molecular formula: C30H41N7O7. Mole weight: 611.69. | |
| GE20372 B | GE20372 B is a tetrapeptide produced by the strain of Streptomyces sp. It is used as a human immunodeficiency virus (HIV-L) protease inhibitor. Molecular formula: C30H41N7O7. Mole weight: 611.69. | |
| GE 2270A | GE 2270A is a thiopeptide antibiotic produced by the strain of Planobispora rosea. It inhibits bacterial protein synthesis and has anti-Gram-positive aerobic and anaerobic bacteria (MIC = 0.03-0.25 μg/mL) and Mycobacterium tuberculosis (MIC = 1 μg/mL) activities. Synonyms: Antibiotic GE 2270A; MDL 62879; Antibiotic MDL 62879; GE-2270A; GE-2270. CAS No. 134861-34-0. Molecular formula: C56H55N15O10S6. Mole weight: 1290.52. | |
| GE 23077A1 | A cyclic peptide antibiotic isolated from actinomadura sp. strain GE23077. It inhibits bacterial RNA polymerase. Synonyms: Antibiotic GE 23077A1; GE-23077-A1. CAS No. 435344-49-3. Molecular formula: C31H49N9O16. Mole weight: 803.77. | |
| GeA-69 | GeA-69 is a cell-permeable allosteric inhibitor of PARP-14 macrodomain 2 with Kd of 860 nM. Synonyms: GeA-69; 2143475-98-1; N-(2-(9H-Carbazol-1-yl)phenyl)acetamide; CHEMBL4226393; N-[2-(9H-Carbazol-1-yl)phenyl]acetamide; GeA69; GeA 69; BCP31007; BDBM50461016; AKOS037515677; BS-16620; HY-108708; CS-0030139; S0732; D81049. CAS No. 2143475-98-1. Molecular formula: C20H16N2O. Mole weight: 300.35. | |
| Gear Clamps | Gear Clamps. |  |
| Geclosporin | Geclosporin is an impurity of cycloporine, which is an immunosuppressant used in the treatment of rheumatoid arthritis, psoriasis, Crohn's disease, nephrotic syndrome, etc. Uses: Immunosuppressant. Synonyms: Cyclosporin G; Cyclosporine G. Grade: ≥90% by HPLC. CAS No. 74436-00-3. Molecular formula: C63H113N11O12. Mole weight: 1216.662. | |
| Gedatolisib | Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ, and mTOR with IC50s of 0.4 nM, 5.4 nM and 1.6 nM, respectively[1]. Gedatolisib is equally effective in both complexes of mTOR, mTORC1 and mTORC2[2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PKI-587; PF-05212384. CAS No. 1197160-78-3. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10681. | |
| Gedatolisib (PF-05212384, PKI-587) | Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM, respectively. Phase 2. Synonyms: PKI587; PKI-587; PKI 587; PF05212384; PF-05212384; PF 05212384; PF5212384; PF-5212384; PF 5212384; Gedatolisib. Grade: >98%. CAS No. 1197160-78-3. Molecular formula: C32H41N9O4. Mole weight: 615.73. | |
| Gedatolisib (PKI-587) | Gedatolisib (PF-05212384, PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ and mTOR with IC50 of 0.4 nM, 5.4 nM and 1.6 nM in cell-free assays, respectively. Phase 2. Group: Inhibitors. Alternative Names: PF-05212384. CAS No. 1197160-78-3. Pack Sizes: 5mg. Product ID: S2628. Formula: C32H41N9O4. Smiles: CN(C)C1CCN(CC1)C(=O)C2=CC=C(C=C2)NC(=O)NC3=CC=C(C=C3)C4=NC(=NC(=N4)N5CCOCC5)N6CCOCC6. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Gedatolisib (Standard) | Gedatolisib (Standard) is the analytical standard of Gedatolisib. This product is intended for research and analytical applications. Gedatolisib (PKI-587) is a highly potent dual inhibitor of PI3Kα, PI3Kγ, and mTOR with IC50s of 0.4 nM, 5.4 nM and 1.6 nM, respectively[1]. Gedatolisib is equally effective in both complexes of mTOR, mTORC1 and mTORC2[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1197160-78-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10681R. | |
| Gedivumab | Gedivumab (MHAA4549A; RG7745) is a human monoclonal antibody that targets influenza A virus (IAV) with high specificity and binds to the highly conserved stem region of the IAV haemagglutinin protein, thereby preventing haemagglutinin maturation and blocking haemagglutinin-mediated membrane fusion in the intranucleosome. Gedivumab can be used in IAV infection disease studies[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MHAA4549A; RG7745. CAS No. 1807954-17-1. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99637. | |
| Gedunin | Method for Determining Identity: Group: Biochemicals. Alternative Names: (1S, 3aS, 4aR, 4bS, 5R, 6aR, 10aR, 10bR, 12aS) -5- (Acetyloxy) -1- (3-furanyl) -1, 5, 6, 6a, 7, 10a, 10b, 11, 12, 12a, decahydro-4b, 7, 7, 10a, 12a, -pentamethyloxireno [c]phenanthro [1, 2-d]pyran-3, 8 (3aH, 4bH) -dione. Grades: Purified. CAS No. 2753-30-2. Pack Sizes: 10mg. US Biological Life Sciences. |  Worldwide |
| Gedunin | Gedunin is a naturally occurring Hsp90 inhibitor. Induces Hsp90-dependent client protein degradation and displays antiproliferative activity in vitro (IC50 values are 3.22, 8.84 and 16.8 μM in SKBr3, MCF-7 and CaCo-2 cancer cell lines respectively). It also exhibits antimalarial activity against P. falciparum (IC50 values are 0.14 and 3.1 μM in parasite development and [3H]-hypoxanthine uptake assays respectively). Grade: >98%. CAS No. 2753-30-2. Molecular formula: C28H34O7. Mole weight: 482.57. | |
| Gedunin | Gedunin Inhibitor. Uses: Scientific use. Product Category: T21883. CAS No. 2753-30-2. |  |
| Gefapixant | Gefapixant is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant can be used for the research of chronic cough and knee osteoarthritis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-7264; AF-219. CAS No. 1015787-98-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101588. | |
| Gefapixant | Gefapixant is a P2X3 receptor (P2X3R) antagonist with IC50s of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. It is under a clinical trial for the treatment of chronic cough. Synonyms: AF-219; MK-7264. CAS No. 1015787-98-0. Molecular formula: C14H19N5O4S. Mole weight: 353.4. | |
| Gefapixant citrate | Gefapixant citrate is an orally active and potent purinergic P2X3 receptor (P2X3R) antagonist, with IC50 values of ~30 nM versus recombinant hP2X3 homotrimers and 100-250 nM at hP2X2/3 heterotrimeric receptors. Gefapixant citrate can be used for the research of chronic cough and knee osteoarthritis[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-7264 citrate; AF-219 citrate. CAS No. 2310299-91-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101588A. | |
| Gefapixant Impurity 1 | Gefapixant Impurity 1. Uses: For analytical and research use. CAS No. 865304-71-8. Molecular formula: C14H18N4O2. Mole weight: 274.32. Catalog: APB865304718. |  |
| Gefapixant Impurity 10 | Gefapixant Impurity 10. Uses: For analytical and research use. Molecular formula: C15H21N5O. Mole weight: 287.37. Catalog: APB12141. | |
| Gefapixant Impurity 11 | Gefapixant Impurity 11. Uses: For analytical and research use. Molecular formula: C14H20N6O4S. Mole weight: 368.41. Catalog: APB12142. | |
| Gefapixant Impurity 12 | Gefapixant Impurity 12. Uses: For analytical and research use. Molecular formula: C15H20N4O5S. Mole weight: 368.41. Catalog: APB12143. | |
| Gefapixant Impurity 13 | Gefapixant Impurity 13. Uses: For analytical and research use. Molecular formula: C17H24N4O5S. Mole weight: 396.46. Catalog: APB12144. | |
| Gefapixant Impurity 2 | Gefapixant Impurity 2. Uses: For analytical and research use. CAS No. 2413718-92-8. Molecular formula: C14H18N4O4S. Mole weight: 338.38. Catalog: APB2413718928. | |
| Gefapixant Impurity 3 | Gefapixant Impurity 3. Uses: For analytical and research use. Molecular formula: C13H18N6O3S. Mole weight: 338.39. Catalog: APB12137. | |
| Gefapixant Impurity 4 | Gefapixant Impurity 4. Uses: For analytical and research use. Molecular formula: C13H16BrN5O3S. Mole weight: 402.27. Catalog: APB12138. | |
| Gefapixant Impurity 5 | Gefapixant Impurity 5. Uses: For analytical and research use. Molecular formula: C13H17N5O3S. Mole weight: 323.37. Catalog: APB12136. | |
| Gefapixant Impurity 6 | Gefapixant Impurity 6. Uses: For analytical and research use. Molecular formula: C15H20N6O2. Mole weight: 316.37. Catalog: APB12139. | |
| Gefapixant Impurity 7 | Gefapixant Impurity 7. Uses: For analytical and research use. CAS No. 2527107-23-7. Molecular formula: C20H25N5O3. Mole weight: 383.45. Catalog: APB2527107237. | |
| Gefapixant Impurity 8 | Gefapixant Impurity 8. Uses: For analytical and research use. CAS No. 2527107-24-8. Molecular formula: C20H25N5O3. Mole weight: 383.45. Catalog: APB2527107248. | |
| Gefapixant Impurity 9 | Gefapixant Impurity 9. Uses: For analytical and research use. Molecular formula: C23H28N4O3. Mole weight: 408.5. Catalog: APB12140. | |
| Gefarnate | Gefarnate is a drug used for the treatment of gastritis and gastric ulcer, in vivo, the instillation of gefarnate reduced corneal epithelial damage from desiccation in a dose-dependent fashion. Besides Gefarnate has been proposed for use in the treatment of dry eye syndrome. Synonyms: [(2E)-3,7-dimethylocta-2,6-dienyl] (4E,8E)-5,9,13-trimethyltetradeca-4,8,12-trienoate; Farnesylacetate, Geranyl; Gefarnate; Gefarnil; Gepharnate; Geranyl Farnesylacetate; Ulco. CAS No. 51-77-4. Molecular formula: C27H44O2. Mole weight: 400.64. | |
| Gefarnate | Gefarnate. Group: Biochemicals. Alternative Names: Geranyl farnesylacetate. Grades: Highly Purified. CAS No. 51-77-4. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C27H44O2. US Biological Life Sciences. | Worldwide |
| Gefitinib | Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy and cell apoptosis, which can be used for cancer related research, such as Lung cancer and breast cancer [1][2][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: ZD1839. CAS No. 184475-35-2. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 500 mg; 1 g; 5 g. Product ID: HY-50895. | |
| Gefitinib | Gefitinib. Group: Biochemicals. Grades: Highly Purified. CAS No. 184475-35-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C22H24ClFN4O3. US Biological Life Sciences. | Worldwide |
| Gefitinib | Gefitinib is an antineoplastic drug. Gefitinib effectively inhibits all tyrosine phosphorylation sites on EGFR in both the high and low EGFR-expressing cell lines including NR6, NR6M and NR6W cell lines. The phosphorylation sites Tyr1173 and Tyr992 are less sensitive requiring higher concentrations of Gefitinib for inhibition. Synonyms: ZD1839; ZD 1839; ZD-1839; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine; Iressa; gefitinibum. Grade: >98%. CAS No. 184475-35-2. Molecular formula: C22H24ClFN4O3. Mole weight: 446.90. | |
| Gefitinib | Gefitinib (ZD1839) is an EGFR first-generation inhibitor with oral activity that inhibits the EGFR 19 Del and L858R mutations. Gefitinib has antitumor activity and is used for the treatment of EGFR-mutated non-small-cell lung cancers. Gefitinib administration RESULTS in the development of the EGFR C797S resistance mutation. Category: Active pharmaceutical ingredients. CAS No. 184475-35-2. Product ID: API184475352. Molecular formula: C22H24ClFN4O3. Mole weight: 446.9. |  |
| Gefitinib | 100mg Pack Size. Group: Bioactive Small Molecules, Biochemicals, Research Organics & Inorganics. Formula: C22H24ClFN4O3. CAS No. 184475-35-2. Prepack ID 57220562-100mg. Molecular Weight 446.9. See USA prepack pricing. |  |
| GEFITINIB | GEFITINIB. CAS No. 184475-35-2. Tyger suppliers of organic specialty chemicals & custom chemical synthesis. |  |
| Gefitinib 3,4-Difluoro Impurity HCl | Gefitinib 3,4-Difluoro Impurity HCl. Grade: > 95%. CAS No. 184475-68-1. Molecular formula: C22H25F2N4O3Cl. Mole weight: 466.92. | |
| Gefitinib 4-Desfluoro Impurity HCl | Gefitinib 4-Desfluoro Impurity HCl. Grade: > 95%. Molecular formula: C22H26Cl2N4O3. Mole weight: 465.38. | |
| Gefitinib-based PROTAC 3 | Gefitinib-based PROTAC 3, conjugating an EGFR binding element to a von Hippel-Lindau ligand via a linker, induces EGFR degradation with DC50s of 11.7 nM and 22.3 nM in HCC827(exon 19 del) and H3255 (L858R mutantion) cells, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2230821-27-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-123921. | |
| Gefitinib Chloro Impurity | Gefitinib Chloro Impurity. Grade: > 95%. Molecular formula: C16H21Cl2N3O3. Mole weight: 374.27. | |
| Gefitinib-d3 | Labeled Gefitinib. Gefitinib is an antineoplastic. Group: Biochemicals. Alternative Names: N-(3-Chloro-4-fluorophenyl)-7-(methoxy-d3)-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine; Iressa-d3; ZD 1839-d3. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Gefitinib-d3 | Gefitinib-d3 (ZD1839-d3) is the deuterium labeled Gefitinib. Gefitinib (ZD1839) is a potent, selective and orally active EGFR tyrosine kinase inhibitor with an IC50 of 33 nM. Gefitinib selectively inhibits EGF-stimulated tumor cell growth (IC50 of 54 nM) and that blocks EGF-stimulated EGFR autophosphorylation in tumor cells. Gefitinib also induces autophagy. Gefitinib has antitumour activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1173976-40-3. Pack Sizes: 1 mg. Product ID: HY-50895S2. | |
| Gefitinib-[d3] | Gefitinib-[d3] is the labelled analogue of Gefitinib. Gefitinib is an EGFR inhibitor. It is used for the treatment of certain breast, lung and other cancers. Synonyms: Gefitinib D3; N-(3-Chloro-4-fluorophenyl)-7-(methoxy-d3)-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine. Grade: 98% by HPLC; 99% atom D. CAS No. 1173976-40-3. Molecular formula: C22H21D3ClFN4O3. Mole weight: 449.92. | |
| Gefitinib-d6 | Gefitinib-d6 is a deuterated compound of Gefitinib. Gefitinib has a CAS number of 184475-35-2. Gefitinib is an EGFR tyrosine kinase inhibitor and can inhibit Tyr1173, Tyr992, Tyr1173 and Tyr992 (IC50s: 37/37/26/57 nM). Category: Active pharmaceutical ingredients. CAS No. 1228664-49-0. Product ID: API1228664490. Molecular formula: C22H18D6ClFN4O3. Mole weight: 452.94. | |
| Gefitinib-[d6] | One of the isotopic labelled form of Gefitinib, which could be used as an antineoplastic agent. Synonyms: Gefitinib-d6; N-(3-Chloro-4-fluorophenyl)-7-methoxy-6-[3-(4-morpholinyl)propoxy]-4-quinazolinamine-d6; Iressa-d6. CAS No. 1228664-49-0. Molecular formula: C22H18ClFN4O3D6. Mole weight: 452.95. | |
| Gefitinib-d8ZD1839 D8, Gefitinib D8 | Gefitinib is an EGFR tyrosine kinase inhibitor, with IC50 of 2-37 nM in NR6wtEGFR cells. Gefitinib D8is a deuterium labeled Gefitinib. Category: Active pharmaceutical ingredients. CAS No. 857091-32-8. Product ID: API857091328. Molecular formula: C22H24ClFN4O3. Mole weight: 454.95. | |
| Gefitinib Difluoro Impurity | Gefitinib Difluoro Impurity. Uses: For analytical and research use. CAS No. 184475-50-1. Molecular formula: C22H24F2N4O3. Mole weight: 430.46. Catalog: APB184475501. | |
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