A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
GelMA, 30% methacrylation, Green Fluorescent. Uses: For analytical and research use. Alternative Names: Gelatin Methacryloyl, 30% methacrylation, Green Fluorescent. Catalog: APB12504.
GelMA, 30% methacrylation, Red Fluorescent
GelMA, 30% methacrylation, Red Fluorescent. Uses: For analytical and research use. Alternative Names: Gelatin Methacryloyl, 30% methacrylation, Red Fluorescent. Catalog: APB12505.
GelMA, 60% methacrylation
GelMA (Gelatin Methacryloyl), 60% methacrylation, is a derivative obtained by the reaction of Methacrylic anhydride (MA) (HY-W017330) and gelatin. GelMA exhibits excellent biocompatibility, biodegradability, and moldability. GelMA can be photocrosslinked into hydrogels and can be used for research in regeneration of tissues, such as skin, tendon, bone, cartilage, blood vessel, and cardiovascular system. GelMA hydrogel also can be used for research on drug delivery, organ-on-a-chip, and biosensing[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gelatin Methacryloyl, 60% methacrylation. CAS No. 2280018-77-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W763582A.
GelMA, 60% methacrylation, Green Fluorescent
GelMA, 60% methacrylation, Green Fluorescent. Uses: For analytical and research use. Alternative Names: Gelatin Methacryloyl, 60% methacrylation, Green Fluorescent. Catalog: APB12498.
GelMA, 60% methacrylation, red fluorescent
GelMA, 60% methacrylation, red fluorescent. Uses: For analytical and research use. Alternative Names: Gelatin Methacryloyl, 60% methacrylation, red fluorescent. Catalog: APB12492.
GelMA, 90% methacrylation
GelMA (Gelatin Methacryloyl), 90% methacrylation, is a derivative obtained by the reaction of Methacrylic anhydride (MA) (HY-W017330) and gelatin. GelMA exhibits excellent biocompatibility, biodegradability, and moldability. GelMA can be photocrosslinked into hydrogels and can be used for research in regeneration of tissues, such as skin, tendon, bone, cartilage, blood vessel, and cardiovascular system. GelMA hydrogel also can be used for research on drug delivery, organ-on-a-chip, and biosensing[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gelatin Methacryloyl, 90% methacrylation. CAS No. 2280018-77-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W763582B.
GelMA, 90% methacrylation, Green Fluorescent
GelMA, 90% methacrylation, Green Fluorescent. Uses: For analytical and research use. Alternative Names: Gelatin Methacryloyl, 90% methacrylation, Green Fluorescent. Catalog: APB12491.
Gelomulide A
Gelomulide A is isolated from Suregada. Alternative Names: (3β,5β,9β,10α,12β,14β)-16-Oxo-8,14:12,16-diepoxyabiet-13(15)-en-3-yl acetate. Grades: 98%. CAS No. 122537-59-1. Molecular formula: C22H30O5. Mole weight: 374.471.
Gelomulide B
Gelomulide B is a diterpenoid found in Suregada multiflora. Alternative Names: (3S,4aS,6aS,7aR,10aS,11aS,11bR,11cR)-4,4,8,11c-tetramethyl-9-oxo-1,2,3,4,4a,5,6,7a,9,11a,11b,11c-dodecahydrobis(oxireno)[2',3':1,10a;2'',3'':3,4]phenanthro[3,2-b]furan-3-yl acetate. Grades: 97.5%. CAS No. 122537-60-4. Molecular formula: C22H28O6. Mole weight: 388.454.
Gelomulide N
Gelomulide N also called 1alpha,3beta-Diacetoxy-8beta,14beta-epoxy-ent-abiet-13(15)-en-16,12-olide, is a natural diterpenoid compound. Alternative Names: 1alpha,3beta-Diacetoxy-8beta,14beta-epoxy-ent-abiet-13(15)-en-16,12-olide;1-epi-Gelomulide O. Grades: >97%. CAS No. 1005212-02-1. Molecular formula: C24H32O7. Mole weight: 432.51.
Gelsemine
Gelsemine, an alkaloid from the Chinese herb Gelsemium elegans, is effective in mitigating chronic pain. Antinociceptive effects. Uses: Scientific research. Category: Natural products. CAS No. 509-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0388.
Gelsemine
Gelsemine. Group: Biochemicals. Grades: Plant Grade. CAS No. 509-15-9. Pack Sizes: 10mg. Molecular Formula: C20H22N2O2, Molecular Weight: 322.4. US Biological Life Sciences.
Gelsevirine, isolated from the herbs of Gelsemium elegans, could be developed as the treatment of anxiety-related disorders in human patients. Their anxiolytic mechanism may be involved in the agonist action of glycine receptor in the brain. Uses: Anxiolytic. Alternative Names: Gelsemine, 1-methoxy-; 1-Methoxygelsemine. Grades: >98%. CAS No. 38990-03-3. Molecular formula: C21H24N2O3. Mole weight: 352.4.
Gelucire 44/14
Gelucire 44/14 is a non-ionic water-dispersed surfactant used in lipid-based formulations to solubilize and increase the oral bioavailability of less water-soluble APIs. It is self-emulsified in the aqueous medium to form a fine dispersion, i.e., microemulsion (SMEDDS). Alternative Names: Lauroyl Polyoxyl-32 glycerides; Lauroyl Macrogol-32 glycerides; Gelucire® 44/14. Grades: ≥95%. CAS No. 121548-04-7.
Gelucire 44/14
Gelucire 44/14 is a potential and safe absorption enhancer for improving the absorption of poorly absorbable agents including insulin and calcitonin by pulmonary delivery. Uses: Scientific research. Category: Signaling pathways. CAS No. 121548-04-7. Pack Sizes: 25 g; 50 g; 100 g. Product ID: HY-Y1892.
GEM144
GEM144 is a potent and orally active DNA polymerase α (POLA1) and HDAC 11 dual inhibitor. GEM144 induces acetylation of p53, activation of p21, G1/S cell cycle arrest, and apoptosis. GEM144 has significant antitumor activity in human orthotopic malignant pleural mesothelioma xenografts[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2487526-28-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-143411.
GEM-5
GEM-5, a gemcitabine-based conjugate incorporating a HIF-1α inhibitor (YC-1) (IC 50 =30 nM), notably suppresses HIF-1α expression while enhancing tumor suppressor p53 expression. It induces apoptosis in A2780 cells and curbs tumor growth. Category: Active pharmaceutical ingredients. CAS No. 2233543-49-0. Product ID: API2233543490. Molecular formula: C32H29F2N5O8. Mole weight: 649.6.
Gem-C12
Gem-C12 is a prodrug of Gemcitabine (HY-17026). Gem-C12 terminates DNA chain elongation, inhibits nucleic acid synthesis and induces Apoptosis. Gem-C12 inhibits the proliferation of glioma cells. Gem-C12 and Honokiol (HY-N0003) exhibit synergistic anti-glioblastoma activity. Gem-C12 can be used in research related to glioblastoma multiforme[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 849139-19-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-185323.
Gemcabene
Gemcabene is an orally available lipid-lowering small molecule designed to target known lipid metabolic pathways, as an adjunctive therapy to reduce LDL-C, hsCRP and triglycerides (TGs). Currentl, Gemcabene is under Phase-II clinical trials in Hypertriglyceridaemia in USA. Alternative Names: 6-(5-carboxy-5-methyl-hexoxy)-2,2-dimethyl-hexanoic acid; gemcabene; 6,6'-oxybis(2,2-dimethylhexanoic acid); PD72953; PD 72953; PD-72953. Grades: >98%. CAS No. 183293-82-5. Molecular formula: C16H30O5. Mole weight: 302.41.
Gemcitabine
Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis. Category: Active pharmaceutical ingredients. CAS No. 95058-81-4. Product ID: API95058814. Molecular formula: C9H11F2N3O4. Mole weight: 263.2.
Gemcitabine
Gemcitabine is a nucleoside analogue used in chemotherapy. It treats cancers including testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer and bladder cancer. Alternative Names: 2'-Deoxy-2',2'-difluorocytidine; 2'-Deoxy-2',2'-difluoro-D-cytidine; 2',2'-Difluoro-2'-deoxycytidine; 4-amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 2',2'-Difluorodeoxycytidine; DDFC; DFdC; Folfugem; GemLip; Gemcel; NSC 613327; Gemzar. Grades: ≥95%. CAS No. 95058-81-4. Molecular formula: C9H11F2N3O4. Mole weight: 263.20.
Gemcitabine
Gemcitabine, a nucleic acid synthesis inhibitor, is a very potent and specific deoxycytidine analogue, used as chemotherapy. Gemcitabine induces a potent p53-dependent apoptosis. Group: Inhibitors. Alternative Names: LY-188011, NSC 613327. CAS No. 95058-81-4. Pack Sizes: 50mg. Product ID: S1714. Formula: C9H11F2N3O4. Smiles: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F. Storage Conditions: powder, 4°C,3 years (in the dark) ; in solvent, -80°C,1 year (in the dark).
United States; Europe
Gemcitabine
Gemcitabine (LY 188011) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, and can modulate autophagy. Gemcitabine induces apoptosis through the activation of p38 MAPK. Gemcitabine demonstrates efficacy in mouse models of pancreatic and breast cancer. Gemcitabine can be used for cancer research, such as pancreatic cancer, non-small cell lung cancer, and breast cancer[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 188011. CAS No. 95058-81-4. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg; 1 g; 5 g. Product ID: HY-17026.
Gemcitabine-13C,15N2
antimetabolite and an antineoplastic agent. Gemcitabine inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 188011-13C,15N2. CAS No. 1233921-74-8. Pack Sizes: 1 mg; 5 mg. Product ID: HY-17026S.
Gemcitabine-13C,15N2 hydrochloride
Gemcitabine-13C,15N2 (hydrochloride) is the 13C and 15N labeled Gemcitabine hydrochloride[1]. Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 188011-13C,15N2 hydrochloride. CAS No. 2757566-59-7. Pack Sizes: 500 μg. Product ID: HY-B0003S.
Gemcitabine-[13C,15N2] Hydrochloride
Gemcitabine-[13C,15N2] Hydrochloride is the labelled analogue of Gemcitabine. Gemcitabine is an antitumor drug used for the treatment of multiple cancers. Alternative Names: Gemcitabine-13C,15N2 Hydrochloride; 2'-Deoxy-2',2'-difluoro-cytidine-2-13C-1,3-15N2 monohydrochloride; 2'-Deoxy-2',2'-difluorocytidine-13C,15N2 Hydrochloride; 4-Amino-1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one-2-13C-1,3-15N2 hydrochloride. Grades: 95% by HPLC; 95% atom 13C; 95% atom 15N. CAS No. 2757566-59-7. Molecular formula: C8[13C]H11F2N[15N]2O4.HCl. Mole weight: 302.64.
Labeled Gemcitabine, an antineoplastic. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine-13C,15N2 Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemcitabine-5'-diphosphate
A diphosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as an inhibitor of ribonucleotide reductases (RNRs). Alternative Names: 2'-deoxy-2',2'-difluorocytidine 5'-(trihydrogen diphosphate). Grades: ≥ 95 % by HPLC. CAS No. 116371-66-5. Molecular formula: C9H13F2N3O10P2. Mole weight: 423.16.
Gemcitabine 5'-elaidate
Gemcitabine 5'-elaidate. Group: Biochemicals. Alternative Names: (E)-((2R,3R,5R)-5-(4-Amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methyl octadec-9-enoate; 2'-Deoxy-2',2'-difluorocytidine 5'-(9E)-9-octadecenoate; CP-4126; LVT derivative of Gemcitabine; CO-101. Grades: Highly Purified. CAS No. 210829-30-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C27H43F2N3O5. US Biological Life Sciences.
Worldwide
Gemcitabine-5'-triphosphate
A triphosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as a cytotoxic agent and induce apoptosis. Alternative Names: 2',2'-Difluorocytidine-5'-triphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C9H14N3O13P3F2. Mole weight: 503.14.
Gemcitabine alpha-anomer
Gemcitabine alpha-anomer is an anomer of Gemcitabine. Gemcitabine is a nucleoside analog used in chemotherapy to treat cancers including testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer, and bladder cancer. Alternative Names: Gemcitabine EP Impurity B; 4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythropentofuranosyl)pyrimidin-2(1H)-one; Gemcitabine α-anomer; 4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-2(1H)-pyrimidinone; Gemcitabine Impurity B; 1'-Epi Gemcitabine; 4-Amino-1-((2S,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidin-2(1H)-one; 1-(2,2-Difluoro-2-deoxy-α-D-ribofuranosyl)cytosine; α-Gemcitabine; Gemcitabine hydrochloride EP Impurity B. Grades: ≥95%. CAS No. 95058-85-8. Molecular formula: C9H11F2N3O4. Mole weight: 263.20.
Gemcitabine (alpha-Isomer) Hydrochloride
Gemcitabine (alpha-Isomer) Hydrochloride is an α-Anomer of Gemcitabine. Gemcitabine is a nucleoside analogue used in chemotherapy. It treats cancers including testicular cancer, breast cancer, ovarian cancer, non-small cell lung cancer, pancreatic cancer and bladder cancer. Alternative Names: 2(1H)-Pyrimidinone, 4-amino-1-(2-deoxy-2,2-difluoro-α-D-erythro-pentofuranosyl)-, hydrochloride (1:1); Gemcitabine EP Impurity B hydrochloride; 4-Amino-1-(2-deoxy-2,2-difluoro-α-D-erythropentofuranosyl)pyrimidin-2(1H)-one hydrochloride; Gemcitabine α-anomer hydrochloride; Gemcitabine Impurity B hydrochloride; 1'-Epi Gemcitabine hydrochloride; 1-(2,2-Difluoro-2-deoxy-α-D-ribofuranosyl)cytosine hydrochloride; α-Gemcitabine hydrochloride. Grades: >95%. CAS No. 122111-05-1. Molecular formula: C9H12F2N3O4Cl. Mole weight: 299.65.
Gemcitabine Diphosphate Ammonium Salt
Gemcitabine Diphosphate is a phosphorylated metabolite of Gemcitabine, an antineoplastic agent. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine 5-(Trihydrogen Diphosphate) Triethylamine Salt; Gemcitabine 5-Diphosphate Triethylamine Salt. Grades: Highly Purified. CAS No. free acid: 116371-66-5. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemcitabine Diphosphate Choline
Gemcitabine derivative. An antineoplastic agent. Group: Biochemicals. Alternative Names: Gemcitabine 5-Diphosphate Choline. Grades: Highly Purified. CAS No. 1643126-46-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gemcitabine Diphosphate Choline
Gemcitabine derivative. An antineoplastic agent. Alternative Names: Gemcitabine 5'-Diphosphate Choline. Grades: 95%. CAS No. 1643126-46-8. Molecular formula: C14H24F2N4O10P2. Mole weight: 508.31.
Gemcitabine Diphosphate Triethylamine Salt
Gemcitabine Diphosphate is a Gemcitabine phosphorylated metabolite, an antineoplastic agent. Alternative Names: 2'-Deoxy-2',2'-difluorocytidine 5'-(Trihydrogen Diphosphate) Triethylamine Salt; Gemcitabine 5'-Diphosphate Triethylamine Salt. Grades: 90%. Molecular formula: C27H58F2N6O10P2. Mole weight: 726.73.
Gemcitabine elaidate
Gemcitabine elaidate (also known as CO-101; CP-4126) is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. dFdCDP inhibits ribonucleotide reductase, thereby decreasing the deoxynucleotide pool available for DNA synthesis; dFdCTP is incorporated into DNA, resulting in DNA strand termination and apoptosis. Due to its lipophilicity, gemcitabine 5'-elaidic acid ester exhibits an increased cellular uptake and accumulation, resulting in an increased conversion to active metabolites, compared to gemcitabine. In addition, this formulation of gemcitabine may be less susceptible to deamination and deactivation by deoxycytidine deaminase. Alternative Names: CO-101; CO101; CO 101; CP-4126; CP4126; CP 4126. CAS No. 210829-30-4. Molecular formula: C27H43F2N3O5. Mole weight: 527.654.
Gemcitabine elaidate
Gemcitabine elaidate (CP-4126), is a lipophilic, unsaturated fatty acid ester derivative of gemcitabine (dFdC), an antimetabolite deoxynucleoside analogue, with potential antineoplastic activity. Upon hydrolysis intracellularly by esterases, the prodrug gemcitabine is converted into the active metabolites difluorodeoxycytidine di- and tri-phosphate (dFdCDP and dFdCTP) by deoxycytidine kinase. Category: Active pharmaceutical ingredients. Synonyms: Gemcitabine 5'-elaidate, Gemcitabine (elaidate), CO-101, CP-4126. CAS No. 210829-30-4. Product ID: API210829304. Molecular formula: C27H43F2N3O5. Mole weight: 527.64.
Gemcitabine elaidate hydrochloride
Gemcitabine elaidate (CP-4126) hydrochloride is a lipophilic pro-drug of Gemcitabine, converted to Gemcitabine by esterases for phosphorylation. Category: Active pharmaceutical ingredients. Synonyms: Gemcitabine elaidate hydrochloride(210829-30-4(free base)), Gemcitabine 5'-elaidate hydrochloride, CP-4126 hydrochloride, CO-101 hydrochloride. CAS No. 2918768-08-6. Product ID: API2918768086. Molecular formula: C27H44ClF2N3O5. Mole weight: 564.11.
Gemcitabine EP Impurity B
Gemcitabine EP Impurity B. Uses: For analytical and research use. CAS No. 122111-05-1. Molecular formula: C9H11F2N3O4·ClH. Mole weight: 299.66. Catalog: APB122111051.
Gemcitabine hydrochloride
Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 188011 hydrochloride. CAS No. 122111-03-9. Pack Sizes: 10 mM * 1 mL in DMSO; 100 mg; 200 mg; 500 mg; 1 g; 5 g; 10 g. Product ID: HY-B0003.
Gemcitabine hydrochloride
5g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C9H11F2N3O4 · HCl. CAS No. 122111-03-9. Prepack ID 56199790-5g. Molecular Weight 299.66. See USA prepack pricing.
Gemcitabine hydrochloride
Gemcitabine induced NF-κB activity in BxPC-3, PANC-1, and MIA PaCa-2 cells and decreased the level of the NF-κB inhibitor IκBα in BxPC-3 and PANC-1 cells. Uses: Antimetabolites, antineoplastic. Alternative Names: Gemzar; Gemcitabine HCl; LY188011 hydrochloride. Grades: >98%. CAS No. 122111-03-9. Molecular formula: C9H11F2N3O4.HCI. Mole weight: 299.66.
Gemcitabine hydrochloride
Gemcitabine hydrochloride (LY 188011 hydrochloride) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis. Category: Active pharmaceutical ingredients. Synonyms: Gemcitabine HCl, Gemzar, LY 188011 hydrochloride. CAS No. 122111-03-9. Product ID: API122111039. Molecular formula: C9H11F2N3O4·HCl. Mole weight: 299.66.
Gemcitabine Hydrochloride
Gemcitabine is a pyrimidine nucleoside analog antitumor drug that can inhibit DNA synthesis and repair, leading to cell autophagy and apoptosis. It is mainly used to treat various solid tumors such as pancreatic cancer and non-small cell lung cancer, and is often combined with chemotherapy to enhance efficacy. Group: Inhibitors. Alternative Names: NSC 613327 HCl,LY-188011 HCl. CAS No. 122111-03-9. Pack Sizes: 25mg. Product ID: S1149. Formula: C9H11F2N3O4.HCI. Smiles: C1=CN(C(=O)N=C1N)C2C(C(C(O2)CO)O)(F)F.Cl. Storage Conditions: 2 years -80 in solvent.
Gemcitabine is a nucleoside analog of deoxycytidine used as chemotherapy to treat patients with various types of cancer. After passage through the cell membrane via nucleoside transporters, gemcitabine undergoes complex intracellular conversion to gemcitabine diphosphate (dFdCDP) and triphosphate (dFdCTP). dFdCTP inhibits DNA polymerase by competing with deoxycytidine triphosphate (dCTP). dFdCDP inhibits ribonucleoside reductase and DNA synthesis by causing depletion of deoxyribonucleotide pools, and thus potentiating the effects of dFdCTP. Gemcitabine can be inactivated to 2,2'-difluorodeoxyuridine, mainly by deoxycytidine deaminase. Also, 5'-nucleotidase catalyses the conversion of nucleotides to nucleosides and inhibits nucleoside kinases. Group: Biochemicals. Alternative Names: 2-Deoxy-2,2-difluorocytidine Hydrochloride, dFdC, dFdCyd. Grades: Highly Purified. CAS No. 122111-03-9. Pack Sizes: 100mg, 500mg, 1g. US Biological Life Sciences.
Worldwide
Gemcitabine hydrochloride EP impurity A/Lamivudine EP impurity E
Gemcitabine hydrochloride EP impurity A/Lamivudine EP impurity E. Uses: For analytical and research use. CAS No. 71-30-7. Molecular formula: C4H5N3O. Mole weight: 111.1. Catalog: APB71307.
Gemcitabine hydrochloride (Standard)
Gemcitabine (hydrochloride) (Standard) is the analytical standard of Gemcitabine (hydrochloride). This product is intended for research and analytical applications. Gemcitabine Hydrochloride (LY 188011 Hydrochloride) is a pyrimidine nucleoside analog antimetabolite and an antineoplastic agent. Gemcitabine Hydrochloride inhibits DNA synthesis and repair, resulting in autophagyand apoptosis[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: LY 188011 hydrochloride (Standard). CAS No. 122111-03-9. Pack Sizes: 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B0003R.
Gemcitabine Impurity 1
Gemcitabine Impurity 1. Uses: For analytical and research use. Alternative Names: ((2R,3R)-3-(benzoyloxy)-4,4-difluoro-5-oxotetrahydrofuran-2-yl)methyl benzoate. CAS No. 122111-01-7. Molecular formula: C19H14F2O6. Mole weight: 376.31. Catalog: APB122111017.
Gemcitabine Impurity 13
Gemcitabine Impurity 13. Uses: For analytical and research use. Alternative Names: 1-((2R,4R,5R)-3,3-difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione. CAS No. 114248-23-6. Molecular formula: C9H10F2N2O5. Mole weight: 264.18. Catalog: APB114248236.
Gemcitabine Impurity 15
Gemcitabine Impurity 15. Uses: For analytical and research use. Alternative Names: ((2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-4,4-difluoro-3-hydroxytetrahydrofuran-2-yl)methyl benzoate. CAS No. 2174019-90-8. Molecular formula: C16H15F2N3O5. Mole weight: 367.3. Catalog: APB2174019908.
Gemcitabine Impurity 2
Gemcitabine Impurity 2. Uses: For analytical and research use. Molecular formula: C28H32ClNO10. Mole weight: 578.01. Catalog: APB10503.
Gemcitabine Impurity 2
Gemcitabine Impurity 2. Uses: For analytical and research use. Alternative Names: ((2R,3R)-3-(benzoyloxy)-4,4-difluoro-5-hydroxytetrahydrofuran-2-yl)methyl benzoate. CAS No. 143157-22-6. Molecular formula: C19H16F2O6. Mole weight: 378.32. Catalog: APB143157226.
Gemcitabine Impurity 3
Gemcitabine Impurity 3. Uses: For analytical and research use. Alternative Names: (2R,3R)-4,4-difluoro-2,5-dihydroxypentane-1,3-diyl dibenzoate. Molecular formula: C19H18F2O6. Mole weight: 380.34. Catalog: APB02182.
Gemcitabine Impurity 3
Gemcitabine Impurity 3. Uses: For analytical and research use. CAS No. 153381-14-7. Molecular formula: C9H10F2N2O5. Mole weight: 264.18. Catalog: APB153381147.
Gemcitabine Impurity 4
Gemcitabine Impurity 4. Uses: For analytical and research use. CAS No. 95058-77-8. Molecular formula: C5H6F2O4. Mole weight: 168.1. Catalog: APB95058778.
Gemcitabine Impurity 4
Gemcitabine Impurity 4. Uses: For analytical and research use. Alternative Names: ((2R,3R,5R)-3-(benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate. CAS No. 134877-42-2. Molecular formula: C20H18F2O8S. Mole weight: 456.41. Catalog: APB134877422.
Gemcitabine Impurity 5
Gemcitabine Impurity 5. Uses: For analytical and research use. CAS No. 122111-12-0. Molecular formula: C5H6F2O4. Mole weight: 168.1. Catalog: APB122111120.
Gemcitabine Impurity 5
Gemcitabine Impurity 5. Uses: For analytical and research use. Alternative Names: ((2R,3R,5S)-3-(benzoyloxy)-4,4-difluoro-5-((methylsulfonyl)oxy)tetrahydrofuran-2-yl)methyl benzoate. CAS No. 134877-43-3. Molecular formula: C20H18F2O8S. Mole weight: 456.41. Catalog: APB134877433.
Gemcitabine Impurity 6
Gemcitabine Impurity 6. Uses: For analytical and research use. CAS No. 122111-02-8. Molecular formula: C19H14F2O6. Mole weight: 376.31. Catalog: APB122111028.
Gemcitabine Impurity 7
Gemcitabine Impurity 7. Uses: For analytical and research use. CAS No. 122111-07-3. Molecular formula: C12H10F2O5. Mole weight: 272.2. Catalog: APB122111073.
Gemcitabine Impurity 7
Gemcitabine Impurity 7. Uses: For analytical and research use. Alternative Names: (2R,3R,5R)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4,4-difluorotetrahydrofuran-3-yl benzoate. CAS No. 134790-39-9. Molecular formula: C23H19F2N3O6. Mole weight: 471.41. Catalog: APB134790399.
Gemcitabine Impurity 8
Gemcitabine Impurity 8. Uses: For analytical and research use. Alternative Names: (2R,3R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2-((benzoyloxy)methyl)-4,4-difluorotetrahydrofuran-3-yl benzoate. CAS No. 134790-40-2. Molecular formula: C23H19F2N3O6. Mole weight: 471.41. Catalog: APB134790402.
Gemcitabine Impurity 8
Gemcitabine Impurity 8. Uses: For analytical and research use. CAS No. 143234-91-7. Molecular formula: C14H16F2O6. Mole weight: 318.27. Catalog: APB143234917.
Gemcitabine Impurity 9
Gemcitabine Impurity 9. Uses: For analytical and research use. CAS No. 866473-31-6. Molecular formula: C19H16F2O7. Mole weight: 394.33. Catalog: APB866473316.
Gemcitabine monophosphate
Gemcitabine monophosphate (Gemcitabine 5-phosphate) is one of the active intermediates of Gemcitabine (HY-17026). Gemcitabine monophosphate has a synergistic anti-cancer effect and can be delivered by formulating it into nanoparticles[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gemcitabine 5-phosphate. CAS No. 116371-67-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108932.
Gemcitabine monophosphate
R306465 is a novel HDAC inhibitor with broad-spectrum antitumor activity against solid (IC50: 30 to 300 nM) and hematological malignancies. R306465 was found to be a potent inhibitor of HDAC1 and -8 (class I) in vitro. Category: Active pharmaceutical ingredients. Synonyms: GemMP, Gemcitabine 5-phosphate. CAS No. 116371-67-6. Product ID: API116371676. Molecular formula: C9H12F2N3O7P. Mole weight: 343.18.
Gemcitabine Monophosphate
A monophosphorylated derivative of Gemcitabine and has been found to exhibit potent activities as a cytotoxic agent and induce apoptosis. Alternative Names: 2',2'-difluorodeoxycytidine Monophosphate; Gemcitabine 5'-phosphate. Grades: ≥ 95 % by HPLC. CAS No. 116371-67-6. Molecular formula: C9H12F2N3O7P. Mole weight: 343.18.
Gemcitabine Monophosphate-13C,15N2 Formate Salt
Gemcitabine Monophosphate-13C,15N2 Formate Salt. Group: Biochemicals. Alternative Names: 2'-Deoxy-2',2'-difluoro-5'-cytidylic Acid-13C,15N2 Formate. Grades: Highly Purified. Pack Sizes: 1mg. Molecular Formula: C913CH14F2N15N2O9P, Molecular Weight: 392.18. US Biological Life Sciences.