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Gastrin I (human) (sulfated) is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development[1]. Uses: Scientific research. Category: Peptides. CAS No. 19361-51-4. Pack Sizes: 100 μg; 500 μg; 1 mg; 5 mg. Product ID: HY-P5055.
Gastrin II Sulfated
Gastrin II Sulfated. Synonyms: Gastrin I (human) (sulfated); PYR-GLY-PRO-TRP-LEU-GLU-GLU-GLU-GLU-GLU-ALA-TYR(SO3H)-GLY-TRP-MET-ASP-PHE-NH2. CAS No. 19361-51-4. Molecular formula: C97H124N20O34S2. Mole weight: 2178.27.
Gastrin I rat
Gastrin I can be used to determine the expression of histidine decarboxylase and histamine metabolism. CAS No. 81123-06-0. Molecular formula: C94H128N22O31S2. Mole weight: 2126.28.
Gastrin Releasing Peptide human
Gastrin Releasing Peptide human. Uses: For analytical and research use. CAS No. 93755-85-2. Mole weight: 2859.38. Catalog: AP93755852.
Gastrin-Releasing Peptide, human
Gastrin-Releasing Peptide, human (GRP), one of the bombesin-like peptide family, is an agonist for the gastrin-releasing peptide receptor (GRPR) and it plays only a perfunctory role in the mediation of pituitary hormone release. Synonyms: Gastrin-Releasing Peptide, human; H-Val-Pro-Leu-Pro-Ala-Gly-Gly-Gly-Thr-Val-Leu-Thr-Lys-Met-Tyr-Pro-Arg-Gly-Asn-His-Trp-Ala-Val-Gly-His-Leu-Met-NH2. CAS No. 93755-85-2. Molecular formula: C130H204N38O31S2. Mole weight: 2859.38.
Gastrin-Releasing Peptide, human
Gastrin-Releasing Peptide, human (GRP) belongs to the bombesin-like peptide family, and is not a classical hypothalamic-hypophyseal regulatory hormone since it plays only a perfunctory role in the mediation of pituitary hormone release. Uses: Scientific research. Category: Signaling pathways. CAS No. 93755-85-2. Pack Sizes: 500 μg; 1 mg; 5 mg; 10 mg. Product ID: HY-P0238.
Gastrin-Releasing Peptide, human(TFA)
Gastrin-releasing peptide is a regulatory human peptide that elicits gastrin release and regulates gastric acid secretion and enteric motor function. Molecular formula: C132H205F3N38O33S2. Mole weight: 2973.40.
Gastrodin
Gastrodin. Group: Biochemicals. Alternative Names: 4- β -D-Glucopyranosyl oxybenzyl alcohol. Grades: Plant Grade. CAS No. 62499-27-8. Pack Sizes: 20mg. Molecular Formula: C13H18O7, Molecular Weight: 286.278. US Biological Life Sciences.
Worldwide
Gastrodin Impurity 1
Gastrodin Impurity 1 is a vital product in the biomedical industry used as an impurity reference standard for the analysis of Gastrodin, a natural compound found in the herb Gastrodia elata. Gastrodin has shown potential in studying neurological disorders, such as Alzheimer's disease, possesses antioxidative and anti-inflammatory properties. Gastrodin Impurity 1 plays a crucial role in ensuring accurate analysand quality control of Gastrodin-based drugs. Synonyms: 4-Formylphenylb-D-glucopyranoside; p-Hydroxybenzaldehyde 4-O-β-D-glucopyranoside; 2'-Formylphenyl-β-D-glucopyranoside; 2-hydroxybenzaldehyde β-D-glucopyranoside; Helecin. Grade: > 95%. CAS No. 26993-16-8. Molecular formula: C13H16O7. Mole weight: 284.26.
Gastrodin Liposome
Gastrodin is a glucoside that can dilate cerebral blood vessels, increase the capacity of brain cells to fight hypoxaemia, improve their ability to carry oxygenated blood throughout the body and reduce its vascular resistance. The product is a pre-formulated liposome containing gastrodin. It is only for research purposes and for the injection to laboratory animals. Group: Drug-loaded liposome.
GAT-100
GAT-100, an indole derivative, has been found to be a negative allosteric modulator that could be used as a covalent probe in studying of the binding motifs of CB1R-allosteric ligand. Synonyms: GAT100; GAT-100; GAT 100; 3-ethyl-5-isothiocyanato-N-(4-(piperidin-1-yl)phenethyl)-1H-indole-2-carboxamide. Grade: 98%. CAS No. 1663564-42-8. Molecular formula: C25H28N4OS. Mole weight: 432.59.
GAT107
GAT107 is an allosteric agonist (EC50 value 28 μM) and positive allosteric modulator (PAM) of α7 nicotinic acetylcholine receptors (nAChR). GAT107 is the bioactive enantiomer of 4BP-TQS. It reverses nociception in mouse models of inflammatory and neuropathic pain. Synonyms: GAT107; GAT-107; GAT 107; (3aR,4S,9bS)-4-(4-bromophenyl)-3a,4,5,9b-tetrahydro-3H-cyclopenta[c]quinoline-8-sulfonamide. Grade: 99%. CAS No. 1476807-74-5. Molecular formula: C18H17BrN2O2S. Mole weight: 405.31.
GAT211
GAT211 is a positive allosteric modulator (PAM) and acts as a selective inhibitor of cannabinoid receptor 1 (CB1). It is a racemic mixture of GAT228 and GAT229. Uses: Cannabinoid receptor agonists. Synonyms: 3-(2-nitro-1-phenylethyl)-2-phenyl-1H-indole. Grade: ≥98%. CAS No. 102704-40-5. Molecular formula: C22H18N2O2. Mole weight: 342.39.
GAT228
GAT228 is the R-(+)-enantiomer of the CB1 positive allosteric modulator (PAM) GAT229 and a component of the racemic mixture GAT211. GAT228 is an allosteric agonist of cannabinoid receptor 1 (CB1). Synonyms: 3-[(1R)-2-nitro-1-phenylethyl]-2-phenyl-1H-indole. Grade: ≥98%. CAS No. 1446648-15-2. Molecular formula: C22H18N2O2. Mole weight: 342.39.
GAT229
GAT229 is the S-(-)-enantiomer of the CB1 positive allosteric modulator (PAM) GAT228 and a component of the racemic mixture GAT211. GAT229 is a positive allosteric modulator of cannabinoid receptor 1 (CB1) which can't activate the receptor on its own but enhances the binding and activity of CB agonists. Uses: Cannabinoid receptor agonists. Synonyms: 3-[(1S)-2-nitro-1-phenylethyl]-2-phenyl-1H-indole; S-(-)-3-(2-Nitro-1-phenylethyl)-2-phenyl-1H-indole. Grade: ≥98%. CAS No. 889860-85-9. Molecular formula: C22H18N2O2. Mole weight: 342.39.
GATA4-NKX2-5-IN-1
GATA4-NKX2-5-IN-1 is a novel potent inhibitor of GATA4-NKX2-5 interaction, significantly reducing mechanical stretch induced hypertrophic growth reflected by an increase in cardiomyocyte cell size and ANP and BNP mRNA levels in response to mechanical stretch. Synonyms: GATA4-IN-3; 3i-1000; 3i 1000; 3i1000; N-[4-(diethylamino)phenyl]-5-methyl-3-phenyl-4-isoxazolecarboxamide. CAS No. 544681-96-1. Molecular formula: C21H23N3O2. Mole weight: 349.43.
Gatifloxacin
Gatifloxacin (CG5501) is an antibiotic of the fourth-generation fluoroquinolone family, that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Category: Active pharmaceutical ingredients. CAS No. 112811-59-3. Product ID: API112811593. Molecular formula: C19H22FN3O4. Mole weight: 375.39.
Gatifloxacin
1g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H22FN3O4. CAS No. 112811-59-3. Prepack ID 32445577-1g. Molecular Weight 375.4. See USA prepack pricing.
Gatifloxacin
Gatifloxacin (AM-1155; BMS-206584; PD135432) is a potent fluoroquinolone antibiotic that can cross the blood-brain barrier, with broad-spectrum antibacterial activity. Gatifloxacin inhibits bacterial type II topoisomerases (IC50=13.8 μg/ml for S. aureus topoisomerase IV) and E. coli DNA gyrase (IC50=0.109 μg/ml)[1]. Gatifloxacin can be used to treat bacterial conjunctivitis in vivo. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AM-1155; BMS-206584; PD135432. CAS No. 112811-59-3. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-10581.
Gatifloxacin
Gatifloxacin. Group: Biochemicals. Grades: Purified. CAS No. 112811-59-3. Pack Sizes: 50mg. US Biological Life Sciences.
Worldwide
Gatifloxacin
Gatifloxacin is an antibiotic of the fourth-generation fluoroquinolone family, and inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Synonyms: 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-; 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; (±)-1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic acid; 1-Cyclopropyl-6-fluoro-8-methoxy-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methyl-piperazin-1-yl)-4-oxo-1,4-dihydro-quinoline-3-carboxylic acid; 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-4-ium-1-yl)-4-oxoquinoline-3-carboxylate; AM 1155; BMS 206584-01; G-Cebran; Gaity; Gatiflo; Gatifloxin; Gatilox; Gatiquin; Gatispan; PD 135432; Tequin; Tymer; Zymar; Zymaxid. Grade: >98%. CAS No. 112811-59-3. Molecular formula: C19H22FN3O4. Mole weight: 375.39.
An antibacterial. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-6-fluoro-1,4-dihydroxy-8-methoxy-7-(3-methyl-1-piperazinyl)-4-oxo-3-quinolinecarboxylic Acid, Tequin. Grades: Highly Purified. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Gatifloxacin 98+%
Gatifloxacin 98+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences.
Gatifloxacin intermediate. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-6,7-difluoro-1,4-dihydro-8-methoxy-4-oxo-3-quinolinecarboxylic Acid Ethyl Ester. Grades: Highly Purified. CAS No. 112811-71-9. Pack Sizes: 250mg. US Biological Life Sciences.
Worldwide
Gatifloxacin-[d3] hydrochloride
An isotope labelled derivative of Gatifloxacin. Gatifloxacin is an antibiotic that inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Synonyms: Gatifloxacin-D3 hydrochloride; 1-Cyclopropyl-6-fluoro-4-oxo-8-methoxy-D3-7-(3-methylpiperazin-1-yl)-1,4-dihydro-quinoline-3-carboxylic acid hydrochloride; Tequin-d3 hydrochloride; Zymar-d3 hydrochloride. Grade: 95% by HPLC; 98% atom D. Molecular formula: C19H20D3ClFN3O4. Mole weight: 414.87.
Gatifloxacin-d4
An antibacterial. Group: Biochemicals. Alternative Names: 1-Cyclopropyl-6-fluoro-1,4-dihydro-8-methoxy-7-(3-methyl-1-piperazinyl-d4)-4-oxo-3-quinolinecarboxylic Acid; Tequin-d4; Zymar-d4. Grades: Highly Purified. CAS No. 1190043-25-4. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Gatifloxacin-d4 HCl
An isotope labelled derivative of Gatifloxacin. Gatifloxacin is an antibiotic that inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Grade: 95% by HPLC; 98% atom D. Molecular formula: C19H18D4FN3O4.HCl. Mole weight: 415.88.
Gatifloxacin Dimer 1
Gatifloxacin Dimer 1 is an impurity of Gatifloxacin which is a new quinolone with antibacterial activity. Synonyms: 7-[4-(3-Carboxy-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-7-quinolyl)-3-methyl-piperazin-1-yl]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-quinoline-3-carboxylic acid. CAS No. 1497338-46-1. Molecular formula: C33H32F2N4O8. Mole weight: 650.63.
Gatifloxacin Dimer 4
Gatifloxacin Dimer 4 is an impurity of Gatifloxacin which is a new quinolone with antibacterial activity. Synonyms: 7-[2-[(3-Carboxy-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-7-quinolyl)amino]ethylamino]-1-cyclopropyl-6-fluoro-8-methoxy-4-oxo-quinoline-3-carboxylic acid. CAS No. 1497338-53-0. Molecular formula: C30H28F2N4O8. Mole weight: 610.56.
Gatifloxacin hydrochloride
Gatifloxacin (hydrochloride) is an antibiotic of the fourth-generation fluoroquinolone family, it inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Synonyms: Gatifloxacin hydrochloride. Grade: >98%. CAS No. 121577-32-0. Molecular formula: C19H23ClFN3O4. Mole weight: 411.86.
Gatifloxacin hydrochloride
Gatifloxacin hydrochloride (AM-1155 hydrochloride) is a fourth-generation fluoroquinolone antibiotic that inhibits bacterial DNA gyrase and topoisomerase IV. Category: Active pharmaceutical ingredients. CAS No. 121577-32-0. Product ID: API121577320. Molecular formula: C19H23ClFN3O4. Mole weight: 411.86.
Gatifloxacin Impurity 1. Uses: For analytical and research use. CAS No. 114213-69-3. Molecular formula: C20H24FN3O4. Mole weight: 389.43. Catalog: APB114213693.
Gatifloxacin mesylate
Gatifloxacin (mesylate) is an antibiotic of the fourth-generation fluoroquinolone family.It also inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Category: Active pharmaceutical ingredients. CAS No. 316819-28-0. Product ID: API316819280. Molecular formula: C20H26FN3O7S. Mole weight: 471.5.
Gatifloxacin Mesylate
Gatifloxacin (mesylate) is an antibiotic of the fourth-generation fluoroquinolone family, it inhibits the bacterial enzymes DNA gyrase and topoisomerase IV. Synonyms: AM 1155 mesylate; BMS 206584-01 mesylate; PD 135432 mesylate; AM1155 mesylate; BMS206584-01 mesylate; PD135432 mesylate; AM-1155 mesylate; BMS-206584-01 mesylate; PD-135432 mesylate. Grade: >98%. CAS No. 316819-28-0. Molecular formula: C20H26FN3O7S. Mole weight: 471.5.
Gatifloxacin N-Oxide
Gatifloxacin N-Oxide. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C19H22FN3O5, Molecular Weight: 391.39. US Biological Life Sciences.
Worldwide
Gatifloxacin N-Oxide
Gatifloxacin N-Oxide is an impurity of Gatifloxacin. Grade: > 95%. CAS No. 1798008-43-1. Molecular formula: C19H22FN3O5. Mole weight: 391.40.
gatifloxacin sesQuihydrate
gatifloxacin sesQuihydrate. Group: Biochemicals. Grades: Highly Purified. CAS No. 180200-66-2. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
Gatifloxacin sesquihydrate
Gatifloxacin is a fourth generation fluoroquinolone antibiotic. Gatifloxacin sesquihydrate is a bacterial DNA gyrase inhibitor used to treat tuberculosis and pneumonia. Grade: ≥98%. CAS No. 180200-66-2. Molecular formula: C19H22FN3O4.3/2(H2O). Mole weight: 402.41.
Gatifloxacin sesquihydrate
Gatifloxacin sesquihydrate, a bacterial DNA gyrase inhibitor, is used to treat tuberculosis and pneumonia. Category: Active pharmaceutical ingredients. CAS No. 180200-66-2. Product ID: API180200662. Molecular formula: C19H24FN3O5. Mole weight: 393.41.
Gatifloxacin sesquihydrate
5g Pack Size. Group: Antibiotics, Bioactive Small Molecules, Research Organics & Inorganics. Formula: C19H22FN3O4 ·1.5H2O. CAS No. 180200-66-2. Prepack ID 89983539-5g. Molecular Weight 402.42. See USA prepack pricing.
Gatifloxacin USP Related Compound E
Iso-Gatifloxacin, an antibiotic of the fluoroquinolone class, exhibits potent activity against a wide range of bacterial infections. It stands as a crucial weapon against susceptible strains of Gram-positive and Gram-negative bacteria. Synonyms: Iso-Gatifloxacin; Isogatifloxacin; 3-Quinolinecarboxylic acid, 1-cyclopropyl-6-fluoro-1,4-dihydro-8-Methoxy-7-(2-Methyl-1-piperazinyl)-4-oxo-. Grade: 95%. CAS No. 1029364-65-5. Molecular formula: C19H22FN3O4. Mole weight: 375.40.
Gatipotuzumab
Gatipotuzumab (PankoMab) is a humanized monoclonal antibody which recognizes the tumor-specific epitope of mucin-1 (TA-MUC1). Gatipotuzumab reveals a potent tumor-specific antibody-dependent cell cytotoxicity (ADCC)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PankoMab; DS-3939a antibody. CAS No. 1264737-26-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99634.
GaTx2
GaTx2. Group: Biochemicals. Grades: Purified. CAS No. 194665-85-5. Pack Sizes: 100ug. US Biological Life Sciences.
Worldwide
GaTx2
GaTx2 is a high affinity ClC-2 blocker (apparent KD ~ 50 pM) with selectivity for ClC-2 over other ClC family members (ClC-0, ClC-1, ClC-3 and ClC-4), CFTR, GABAC, CaCC and KV1.2. GaTx2 slows ClC-2 activation but does not inhibit open ClC-2 channels. Synonyms: Leiuropeptide II. CAS No. 194665-85-5. Molecular formula: C125H199N39O47S6. Mole weight: 3192.54.
Gaultherin
Gaultherin. Group: Biochemicals. Alternative Names: Monotropitoside; Monotropitin. Grades: Plant Grade. CAS No. 490-67-5. Pack Sizes: 10mg. Molecular Formula: C19H26O12, Molecular Weight: 446.403. US Biological Life Sciences.
Worldwide
Gavestinel
Gavestinel is a non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM), displaying >1000-fold selectivity over NMDA, AMPA, and kainate binding sites. Gavestinel exhibits a neuroprotective property in animal models of ischaemic stroke. Uses: Glycine agents. Synonyms: 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-; 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-; 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[3-oxo-3-(phenylamino)-1-propenyl]-, (E)-; 4,6-Dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-1H-indole-2-carboxylic acid; GV 150526; GV 150526X; (E)-4,6-dichloro-3-(3-oxo-3-(phenylamino)prop-1-en-1-yl)-1H-indole-2-carboxylic acid. Grade: ≥95%. CAS No. 153436-22-7. Molecular formula: C18H12Cl2N2O3. Mole weight: 375.21.
Gavestinel sodium salt
Gavestinel is a non-competitive antagonist acting at the strychnine-insensitive glycine binding site of the NMDA receptor-channel complex (Kd = 0.8 nM), displaying > 1000-fold selectivity over NMDA, AMPA and kainate binding sites. Gavestinel exhibits a neuroprotective property in animal models of ischaemic stroke. Synonyms: 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propen-1-yl]-, sodium salt (1:1); 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[(1E)-3-oxo-3-(phenylamino)-1-propenyl]-, monosodium salt; 1H-Indole-2-carboxylic acid, 4,6-dichloro-3-[3-oxo-3-(phenylamino)-1-propenyl]-, monosodium salt, (E)-; GV 150526A. Grade: ≥98% by HPLC. CAS No. 153436-38-5. Molecular formula: C18H11Cl2N2O3Na. Mole weight: 397.19.
Gaxilose
Gaxilose is a synthetic disaccharide and a substrate of intestinal lactase. It can be applicated in a new noninvasive diagnostic test based on urine or serum measurement of D-xylose after lactase cleavage of orally administered gaxilose. Uses: Used in a new noninvasive diagnostic test based on urine or serum measurement of d-xylose after lactase cleavage of orally administered 4-galactosylxylose. Synonyms: 4-O-Galactosyl-D-xylose; 4-O-Galactosylxylose; 4-Galactosylxylose; Gaxilose; (3R,4R,5R)-5-(((2S,3R,4S,5R,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)tetrahydro-2H-pyran-2,3,4-triol. Grade: 98%. CAS No. 14087-31-1. Molecular formula: C11H20O10. Mole weight: 312.27.
GB1107
GB1107 is a potent, selective, orally active inhibitor of Galectin-3 (Gal-3) with a Kd of 37 nM for human Galectin-3. GB1107 reduces human and mouse lung adenocarcinoma growth and blocks metastasis in the syngeneic model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1978336-61-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114409.
GB-110 hydrochloride
GB-110 hydrochloride is a potent, and nonpeptidic protease activated receptor 2 (PAR2) agonist. It selectively induces PAR2-mediated intracellular Ca2+ release in HT29 cells with an EC50 of 0.28 μM. Grade: 99%. Molecular formula: C33H49ClN6O5. Mole weight: 645.23.
GB1908
GB1908 is a selective and orally active galectin-1 inhibitor with Ki values of 57 nM and 72 nM for human and mouse galectin-1, respectively. GB1908 displays >50-fold selectivity over galectin-3. GB1908 can be used for the study of lung cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2573135-31-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-162561.
GB1-Cyanine 3
GB1-Cyanine 3. Group: Biochemicals. Alternative Names: 2-[3-[1-[17-(a-D-Glucopyranosyloxy)-5-oxo-9,12-dioxa-6,15-diazaheptadec-1-yl]-1,3-dihydro-3,3-dimethyl-2H-indol-2-ylidene]-1-propen-1-yl]-1,3,3-trimethyl-3H-indolium; GB1-Cy3. Grades: Highly Purified. CAS No. 1065004-53-6. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C43H63N4O9. US Biological Life Sciences.
Worldwide
GB83
GB83 is a potent PAR2 antagonist. GB83 reverses neutrophil elastase?induced synovitis and pain. GB83 blocks the effect of MET-1 supernatant on NG neurons[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1252806-86-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg. Product ID: HY-124061.
GB 83
GB 83 is a selective antagonist of human protease activated receptor 2 (PAR2) (IC50 = 2 mM). Synonyms: GB83; GB 83; GB-83; N-((S)-3-Cyclohexyl-1-((2S,3S)-1-(2,3-dihydrospiro[indene-1,4'-piperidine]-1'-yl)-3-methyl-1-oxopentan-2-ylamino)-1-oxopropan-2-yl)isoxazole-5-carboxamide. Grade: 99%. CAS No. 1252806-86-2. Molecular formula: C32H44N4O4. Mole weight: 548.72.
GB-88
GB-88 is an oral, selective non-peptide antagonist of PAR2, inhibits PAR2 activated Ca2+ release with an IC50 of 2 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1416435-96-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120261.
GBD-9
GBD-9 is a degrader based on the E3 ubiquitin ligase CRBN that targets BTK and the G1 to S phase transition protein GSPT1. GBD-9 has both PROTAC and molecular glue properties by inducing ubiquitination and proteasomal degradation of target proteins. GBD-9 can efficiently degrade wild-type and mutant BTK (such as C481S mutation) and GSPT1. GBD-9 significantly inhibits tumor cell proliferation by inducing G1 phase arrest in cancer cells, downregulating anti-apoptotic proteins (BCL-2, MCL-1) and activating Caspase-3 to induce apoptosis. GBD-9 is mainly used in the research of hematological tumors such as diffuse large B-cell lymphoma (DLBCL) and acute myeloid leukemia (AML)[1][2][3].GBD-9 is composed of E3 ubiquitin ligase ligand (pink part) 5-Aminothalidomide (HY-W023573), target protein ligand (blue part) Btk Inhibitor: IBT6A (HY-13036A), and PROTAC linker (black part) Nonanoic acid (HY-N7057). Uses: Scientific research. Category: Signaling pathways. CAS No. 2864408-92-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153803.
Gboxin
Gboxin is an oxidative phosphorylation inhibitor in cancer cells, which inhibits the activity of F0F1 ATP synthase. Synonyms: 2-ethyl-1-methyl-3-[2-[[(1R,2S,5R)-5-methyl-2-(1-methylethyl)cyclohexyl]oxy]-2-oxoethyl]-1H-benzimidazolium, monochloride. Grade: ≥98%. CAS No. 2101315-36-8. Molecular formula: C22H33N2O2·Cl. Mole weight: 392.96.
Gboxin
Gboxin is an oxidative phosphorylation (OXPHOS) inhibitor that targets glioblastoma. Gboxin inhibits the activity of F0F1 ATP synthase. Antitumour activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2101315-36-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111651.
GBR 12783
GBR 12783, a specific, potent and selective dopamine uptake inhibitor, inhibits the [3H]-dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively. It can improve memory performance and increase hippocampal acetylcholine release in rats. Synonyms: Piperazine, 1-[2-(diphenylmethoxy)ethyl]-4-(3-phenyl-2-propen-1-yl)-; 1-(2-(Diphenylmethoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine; 1-(2-(Benzhydryloxy)ethyl)-4-cinnamylpiperazine; 1-[2-(Diphenylmethoxy)ethyl]-4-[(2E)-3-phenyl-2-propen-1-yl]piperazine. Grade: ≥95%. CAS No. 67469-57-2. Molecular formula: C28H32N2O. Mole weight: 412.57.
GBR 12783 dihydrochloride
GBR 12783 dihydrochloride is a specific, potent and selective dopamine uptake inhibitor that inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively. GBR 12783 dihydrochloride can improve memory performance and increase hippocampal acetylcholine release in rats[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 67469-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-100968.
GBR 12783 dihydrochloride
GBR 12783 dihydrochloride is a potent and selective inhibitor of dopamine uptake (IC50 for inhibition of [3H]-dopamine uptake in rat striatal synaptosomes is 1.8 nM). Synonyms: GBR 12783 dihydrochloride; GBR12783 dihydrochloride; GBR-12783 dihydrochloride; 1-(2-Diphenylmethoxyethyl)-4-(3-phenyl-2-propenyl)-piperazine dihydrochloride. Grade: ≥99% by HPLC. CAS No. 67469-75-4. Molecular formula: C28H32N2O.2HCl. Mole weight: 485.5.
GBR 12783 dihydrochloride
GBR 12783 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 67469-75-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GBR-12935
GBR-12935. CAS No. 9060-5-3.
GBR-12935
GBR 12935 is a piperazine derivative and a potent and selective inhibitor of dopamine uptake with IC50 value of 3.7nM. It is found to have multiple binding sites in rat and human brains. It was originally developed in its 3H radiolabelled form for the purpose of mapping the distribution of dopaminergic neurons in the brain by selective labelling of dopamine transporter proteins. It(1-9 nM) dose-dependently inhibited active uptake of [3H]dopamine in homogenates of the nucleus accumbens and could inhibit DA uptake with IC50 value of 3.7nM in vitro. It elevated locomotion to a greater extent in C57BL/6J mice at the maximally active dose of 10 mg/kg in vivo. It shows a Kd value of 1.08nM in dopamine transporter transfected COS-7 cells. It is now widely used in animal research into Parkinson's disease and the dopamine pathways in the brain. Uses: Gbr 12935 inhibits da uptake with ic50 value of 3.7nm in vitro. it elevated locomotion to a greater extent in c57bl/6j mice at the maximally active dose of 10 mg/kg in vivo. it shows a kd value of 1.08nm in dopamine transporter transfected cos-7 cells. Synonyms: GBR-12935; GBR 12935; GBR12935; 1-[2-(Diphenylmethoxy)ethyl]-4-(3-phenylpropyl)piperazine; 1-Hydrocinnamyl-4-[2-(diphenylmethoxy)ethyl]piperazine; Piperazine, 1-(2-(diphenylmethoxy)ethyl)-4-(3-phenylpropyl)-; N-[3-tert-Butyl-1-(4-Methylphenyl)-1H-pyrazol-5-yl]-N-[4-[2-(4-Morpholinyl)ethoxy]naphthalen-1-yl]urea; 1-(2-(Benzhydryloxy)e
GBR 12935 dihydrochloride
GBR 12935 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 67469-81-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GBR-12935 dihydrochloride
GBR 12935 2Hcl is a potent, and selective dopamine reuptake inhibitor. Synonyms: GBR12935 dihydrochloride; GBR-12935 dihydrochloride. Grade: 0.99. CAS No. 67469-81-2. Molecular formula: C28H36Cl2N2O. Mole weight: 487.509.
GBR 13069 dihydrochloride
GBR 13069 dihydrochloride is a potent and selecticve inhibitor of dopamine uptake (IC50 = 40 nM). Synonyms: GBR 13069 dihydrochloride; GBR13069 dihydrochloride; GBR-13069 dihydrochloride; (1-(2-(Bis-(4-fluorophenyl)methoxy)ethyl)-4-(3-phenyl-2-propenyl)piperazine dihydrochloride. CAS No. 67469-45-8. Molecular formula: C28H30F2N2O.2HCl. Mole weight: 521.48.
GBR 13069 dihydrochloride
GBR 13069 dihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 67469-45-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.