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| Product | Description | |
|---|---|---|
| GNE-131 | GNE-131 is a potent and selective inhibitor of human sodium channel NaV1.7, with an IC50 of 3 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1629063-81-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-112279. |  |
| GNE-140 racemate | GNE-140 racemate is a racemate mixture of (R)-GNE-140 and (S)-GNE-140. GNE-140 racemate is a potent lactate dehydrogenase A (LDHA) inhibitor[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1802977-61-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100742. | |
| GNE-207 | GNE-207 is a potent, selective and orally bioavailable inhibitor of the bromodomain of CBP, with an IC50 of 1 nM, exhibits a selectively index of >2500-fold against BRD4 (1). GNE-207 shows excellent CBP potency, with an EC50 of 18 nM for MYC expression in MV-4-11 cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2158266-58-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120028. | |
| GNE 220 hydrochloride | GNE 220 (hydrochloride) is a potent and selective inhibitor of MAP4K4, with an IC50 of 7 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 2448286-21-1. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-U00428A. | |
| GNE-2256 | GNE-2256 (molecule 19), a chemical probe, is an orally active IRAK4 (Interleukin 1 receptor associated kinase 4) inhibitor (IRAK4 Ki=1.4 nM; IL-6 IC50=190 nM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2102170-43-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-148238. | |
| GNE-272 | GNE-272 is a potent and selective CBP/EP300 inhibitor with IC50 values of 0.02, 0.03 and 13 μM for CBP, EP300 and BRD4, respectively. GNE-272 is also a selective in vivo probe for CBP/EP300[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1936428-93-1. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100726. | |
| GNE 2861 | GNE 2861 is a PAK inhibitor that displays group II selectivity. GNE 2861 inhibits PAK4, PAK5 and PAK6 with IC50s of 7.5, 36, 126 nM, respectively. Uses: Scientific research. Category: Signaling pathways. CAS No. 1394121-05-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12632. | |
| GNE-3511 | GNE-3511 has been found to be a DLK, MAP3K12 kinase inhibitor that could probably exhibit protection action of primary neurons. IC50: 0.107 uM (DLK). Alternative Names: GNE-3511; GNE 3511; GNE3511. CHEMBL3393333; SCHEMBL15602439; BDBM50059190; 2-[[6-(3,3-difluoropyrrolidin-1-yl)-4-[1-(oxetan-3-yl)piperidin-4-yl]pyridin-2-yl]amino]pyridine-4-carbonitrile. Grades: 98%. CAS No. 1496581-76-0. Molecular formula: C23H26F2N6O. Mole weight: 440.50. |  |
| GNE-3511 | GNE-3511 is an orally active bioavailable and brain-penetrant dual leucine zipper kinase (DLK) inhibitor with a Ki of 0.5 nM. GNE-3511 can cross the blood-brain-barrier and can be used for the research of neurodegenerative diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1496581-76-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12947. | |
| GNE-371 | GNE-371 is a potent and selective chemical probe for the second bromodomains of human transcription-initiation-factor TFIID subunit 1 and transcription-initiation-factor TFIID subunit 1-like, with an IC50 of 10 nM for TAF1(2). Uses: Scientific research. Category: Signaling pathways. CAS No. 1926986-36-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112803. | |
| GNE-490 | GNE-490, a (thienopyrimidin-2-yl)aminopyrimidine, is a potent pan-PI3K inhibitor with IC50s of 3.5 nM, 25 nM, 5.2 nM, 15 nM for PI3Kα, PI3Kβ, PI3Kδ and PI3Kγ, respectively. GNE-490 has >200 fold selectivity for mTOR (IC50=750 nM). GNE-490 shows potent suppression efficacy profile against MCF7.1 breast cancer xenograft model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1033739-92-2. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-10812. | |
| GNE-495 | GNE-495 is a potent and selective MAP4K4 inhibitor with an IC50 of 3.7 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 1449277-10-4. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100343. | |
| GNE-617 | GNE-617 Inhibitor. Uses: Scientific use. Product Category: T4335. CAS No. 1362154-70-8. |  |
| GNE-617 | GNE-617 is a specific NAMPT inhibitor that inhibits the biochemical activity of NAMPT with an IC50 of 5 nM and exhibits efficacy in xenograft models of cancer. Uses: Scientific research. Category: Signaling pathways. CAS No. 1362154-70-8. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15766. | |
| GNE-618 | GNE-618 is a potent, orally active nicotinamide phosphoribosyl transferase (NAMPT) inhibitor with an IC50 of 6 nM. GNE-618 depletes NAD levels and induces tumor cell death. Anti-tumor activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1362151-42-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-12628. | |
| GNE-6468 | GNE-6468 is a highly potent and selective RORγ (RORc) inverse agonist with an EC50 value of 13 nM for HEK-293 cell. GNE-6468 exhibits an EC50 of 30 nM for IL-17 PBMC[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1677668-27-7. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-19775. | |
| GNE-6640 | GNE-6640 is a selective and non-covalent inhibitor of ubiquitin epecific peptidase 7 (USP7), with IC50 values of 0.75 μM, 0.43 μM, 20.3 μM and 0.23 μM for full length USP7, USP7 catalytic domain, full length USP47 and Ub-MDM2, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2009273-67-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112937. | |
| GNE-6776 | GNE-6776 is a potent and non-covalent USP7 inhibitor with IC50 of 1.34 uM. GNE-6776 targets cellular USP7, MDM2, and p53 signalling pathways, and induces tumor cell death. Alternative Names: GNE 6776; GNE-6776; GNE6776; 5-[6-amino-4-ethyl-5-(4-hydroxyphenyl)-3-pyridyl]-N-methyl-pyridine-2-carboxamide. Grades: 98%. CAS No. 2009273-71-4. Molecular formula: C20H20N4O2. Mole weight: 348.406. | |
| GNE-6776 | GNE-6776 is a selective and orally bioavailable USP7 inhibitor[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2009273-71-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107986. | |
| GNE 6901 | GNE 6901 (compound 40) is a potent GluN2A-selective NMDAR positive allosteric modulator (PAM) with an EC50 of 382 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1698900-69-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-107423. | |
| GNE-781 | GNE-781 is an orally active, highly potent and selective CBP inhibitor with an IC50 of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC50s of 6.2 nM and 5100 nM, respectively. GNE-781 displays antitumor activity in an MOLM-16 AML xenograft model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1936422-33-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-108696. | |
| GNE-7883 | GNE-7883 is a pan-TEAD inhibitor that blocks the association of YAP/TAZ with TEAD. GNE-7883 effectively reduces chromatin accessibility at TEAD motifs, inhibits cell proliferation in multiple cell line models, and achieves strong anti-tumor efficacy in vivo. In addition, GNE-7883 effectively overcomes intrinsic and acquired resistance to KRAS (Kirsten rat sarcoma viral oncogene homolog) G12C inhibitors in multiple preclinical models by inhibiting YAP/TAZ activation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2648450-42-2. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147214. | |
| GNE-7915 | GNE-7915 is a potent, selective and brain-penetrant inhibitor of LRRK2 with an IC50 of 9 nM. Alternative Names: GNE7915; GNE 7915; GNE-7915. CAS No. 1351761-44-8. Molecular formula: C19H21F4N5O3. Mole weight: 443.403. | |
| GNE-8505 | GNE-8505 is an orally active, blood-brain barrier-permeable selective dual leucine zipper kinase (DLK) inhibitor. GNE-8505 has an IC50 of 0.144 μM for pJNK, and EC50 of 0.457 μM for DRG. GNE-8505 inhibits the DLK/JNK pathway, reduces stress-induced c-Jun phosphorylation levels, decreases neuronal death and suppresses axonal degeneration. GNE-8505 reduces phosphorylated c-Jun levels in the retina, spinal cord and brain tissues of mice. GNE-8505 is applicable to research related to Alzheimer's disease and amyotrophic lateral sclerosis (ALS)[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1620573-48-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-114332. | |
| GNE-9605 | GNE-9605 is a potent, orally active, selective Leucine-rich repeat kinase 2 (LRRK2) inhibitor with an IC50 value of 18.7 nM. GNE-9605 inhibits LRRK2 Ser1292 autophosphorylation. GNE-9605 can be used in research of Parkinson's disease (PD) [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1536200-31-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg. Product ID: HY-12282. | |
| GNE-9822 | GNE-9822 is a potent, orally active and selective ITK inhibitor with a Ki value of 0.7 nM, and an EC50 value of 354.5 nM. GNE-9822 has good ADME properties. GNE-9822 can be used in research of asthma[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1557232-32-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-12410. | |
| GNE-987 | GNE-987 is a VHL-dependent BRD4 PROTAC degrader. GNE-987 exhibits picomolar cell BRD4 degradation activity (DC50=0.03 nM for EOL-1 AML cell line). GNE-987 binds equipotently to the BD1 and BD2 bromodomains of BRD4 with low nanomolar affinities (IC50=4.7 and 4.4 nM, respectively). GNE-987 can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2417371-71-0. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-129937A. | |
| GNE-987 | GNE-987, a PROTAC connected by ligands for von Hippel-Lindau and BRD4, is used in PROTAC-Antibody Conjugate (PAC). GNE-987 shows picomolar activity of cell BRD4 degradation (DC50 = 0.03 nM for EOL-1 AML cell line), and binds equipotently to the BD1 and BD2 bromodomains of BRD4 with low nanomolar affinities (IC50s = 4.7 and 4.4 nM, respectively). It combines a potent BET binder / inhibitor, a VHL binding fragment and a 10 methylene spacer moiety. Alternative Names: 7-(3,5-Difluoropyridin-2-yl)-N-(11-(((S)-1-((2S,4R)-4-hydroxy-2-((4-(4-methylthiazol-5-yl)benzyl)carbamoyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-11-oxoundecyl)-2-methyl-10-((methylsulfonyl)methyl)-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carboxamide; N-[11-({7-(3,5-Difluoropyridin-2-yl)-2-methyl-10-[(methylsulfonyl)methyl]-3-oxo-3,4,6,7-tetrahydro-2H-2,4,7-triazadibenzo[cd,f]azulene-9-carbonyl}amino)undecanoyl]-3-methyl-L-valyl-(4R)-4-hydroxy-N-{[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl}-L-prolinamide. Grades: ≥98%. CAS No. 2417371-71-0. Molecular formula: C56H67F2N9O8S2. Mole weight: 1096.31. | |
| GNE-987 GSH linker-1 | GNE-987 GSH linker-1, a PROTAC-linker Conjugate for PAC, comprises the chimeric BET degrader GNE-987 (HY-129937A) and disulfide-containing linker. GNE-987 GSH linker-1 remains inactive as a degrader until intracellular release of GNE-987 via disulfide reduction and linker self-immolation. GNE-987 GSH linker-1 can be used for the research of acute myeloid leukemia[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2417370-39-7. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-129938. | |
| Gnetol | Gnetol is a phenolic compound isolated from the root of Gnetum montanum. Gnetol potently inhibits COX-1 (IC50 of 0.78 μM) and HDAC. Gnetol is a potent tyrosinase inhibitor with an IC50 of 4.5 μM for murine tyrosinase and suppresses melanin biosynthesis. Gnetol has antioxidant, antiproliferative, anticancer and hepatoprotective activity. Gnetol also possesses concentration-dependent α-Amylase, α-glucosidase, and adipogenesis activities[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 86361-55-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-126052. | |
| GNF179 | GNF179 is an optimized 8,8-dimethyl imidazolopiperazine analog that exhibits antimalarial potency (IC50 of 4.8 nM against the multidrug resistant strain W2). GNF179 is orally active[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1261114-01-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15975. | |
| GNF 2 | GNF 2. Group: Biochemicals. Grades: Purified. CAS No. 778270-11-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| GNF2133 | GNF2133 is a potent, selective and orally active DYRK1A inhibitor with IC50s of 0.0062, >50 μM for DYRK1A and GSK3β, respectively. GNF2133 shows good proliferation potency and efficacy on rat and human primary β-cell. GNF2133 significantly improves glucose disposal capacity and increases insulin secretion. GNF2133 has the potential for the research of type 1 diabetes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2561414-56-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-142295. | |
| GNF351 | GNF351 is a full aryl hydrocarbon receptor (AHR) antagonist. GNF351 competes with a photoaffinity AHR ligand for binding to the AHR with an IC50 of 62 nM. GNF351 is minimal toxicity in mouse or human keratinocytes[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1227634-69-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-102023. | |
| GNF362 | GNF362 is a selective, potent, and orally bioavailable inhibitor of inositol trisphosphate 3 kinase B (Itpkb) with an IC50 of 9 nM. GNF362 also inhibits Itpka and Itpkc with IC50 values of 20 nM and 19 nM, respectively. Inositol trisphosphate 3 kinase B (Itpkb) is a Ca2+-dependent kinase, which phosphorylates the 3 position of Ins (1,4,5) P3 to generate inositol 1,3,4,5-tetrakisphosphate [Ins (1,3,4,5) P4][1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1003019-41-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-126750. | |
| GNF4877 | GNF4877 is a potent DYRK1A and GSK3β inhibitor with IC50s of 6?nM and 16?nM, respectively, which leads to blockade of nuclear factor of activated T-cells (NFATc) nuclear export and increased β-cell proliferation (EC50 of 0.66?μM for mouse β (R7T1) cells)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2041073-22-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-129492. | |
| GNF 5 | GNF 5. Group: Biochemicals. Grades: Purified. CAS No. 778277-15-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GNF-5 | GNF-5, the N-hydroxyethyl carboxamide analog of GNF-2, is an orally active Bcr-Abl inhibitor. GNF-5 has Bcr-Abl inhibition activity with an IC50 value of 0.22 μM. GNF-5 has good favorable pharmacokinetic properties. GNF-5 can be used for the research of kinds of cancer including chronic myelogenous leukemia (CML) and breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 778277-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15738. | |
| GNF 5837 | GNF 5837 is a potent and selective pan-Trk inhibitor that blocks tumor gowth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF. GNF 5837 displays antiproliferative effects in cellular Ba/F3 assays with IC50 values of 7, 9 and 11 nM for cells expressing Tel-TrkC, Tel-TrkB and Tel-TrkA respectively. Alternative Names: GNF5837; GNF-5837; GNF 5837. 1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea. CAS No. 1033769-28-6. Molecular formula: C28H21F4N5O2. Mole weight: 535.503. | |
| GNF 5837 | GNF 5837. Group: Biochemicals. Grades: Purified. CAS No. 1033769-28-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GNF-5837 | GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1033769-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13491. | |
| GNF-6231 | GNF-6231 is a porcupine (IC50= 0.8 nM), Pron, and endoplasmic reticulum protein inhibitor with oral activity. GNF-6231 has anticancer activity. GNF-6231 can prevent the activation of the Wnt pathway by blocking the secretion of all Wnt ligands. GNF-6231 can be used in the study of myocardial infarction[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1243245-18-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100408. | |
| GNF-7 | GNF-7 is a multikinase inhibitor. GNF-7 is a Bcr-Abl inhibitor, with IC50s of 133 nM and 61 nM for Bcr-AblWT and Bcr-AblT315I, respectively. GNF-7 also possesses inhibitory activity against both ACK1 (activated CDC42 kinase 1) and GCK (germinal center kinase) with IC50s of 25 nM and 8 nM, respectively. GNF-7 can be used for the research of hematologic malignancies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 839706-07-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10943. | |
| GNF-Pf-2328 | GNF-Pf-2328. Alternative Names: BMH-15; BMH 15; BMH15; 5-{[3-(dimethylamino)propyl]amino}-9,10-dimethyl-8H-thieno[2',3':4,5]pyrimido[2,1-a]phthalazin-8-one. Grades: 95%. CAS No. 380455-04-9. Molecular formula: C20H23N5OS. Mole weight: 381.50. | |
| G-NGA2 N-Glycan | G-NGA2 N-Glycanthe transformative compound engaging in protein modifications. It finds applications in studying glycosylation-related disorders and diseases. Alternative Names: Monogalactosylated asialo, biantennary (G-NGA2); Monogalactosylated, asialo, bi-antennary N-linked glycan; Monogalactosylated, asialo, biantennary N-glycan (G-NGA2); O-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-2)-O-alpha-D-mannopyranosyl-(1-6)-O-[O-beta-D-galactopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-2)-alpha-D-mannopyranosyl-(1-3)]-O-beta-D-mannopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-D-glucose. Grades: ≥90%. CAS No. 103584-68-5. Molecular formula: C56H94N4O41. Mole weight: 1479.35. | |
| GNQWFI | GNQWFI, an anti-Flt1 peptide, is a VEGFR1-specific antagonist. GNQWFI blocks the interaction of VEGFR1 with various VEGFR1 ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF) and inhibits VEGF-induced endothelial cell migration and tube formation. GNQWFI is promising for research of cancer, asthma, and other ocular diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 853995-60-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10831. | |
| GNX-865 | GNX-865 is a mitochondrial permeability transition pore (mPTP) inhibitor that protects against ischemia-reperfusion injury in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1223568-82-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119909. | |
| GO-203 TFA | GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1222186-26-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1925A. | |
| GO-203 TFA | GO-203 is a D-amino acid cell-penetrating peptide inhibitor of MUC1-C dimerization and thereby its oncogenic function. Group: Inhibitors. CAS No. 1222186-26-6. Pack Sizes: 2mg. Product ID: S8674. Formula: C87H170N52O19S2.C2HF3O2. Smiles: C(CCN)CC(C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CS)NC(=O)C(CCC(=O)N)NC(=O)C(CS)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)N.C(=O)(C(F)(F)F)O. Storage Conditions: 2 years -80 in solvent. |  United States; Europe |
| Go6976 | Go6976 is a Protein Kinase C (PKC) inhibitor, with an IC50 of 20 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 136194-77-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10183. | |
| Go 6976 | Go 6976. Group: Biochemicals. Grades: Purified. CAS No. 136194-77-9. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Go6983 | GO6983 is a potent protein kinase C (PKC) inhibitor. GO6893 displays cardioprotective properties; reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia / reperfusion injury. Alternative Names: Go6983, Go-6983; Go 6983; GO6983. Grades: >98%. CAS No. 133053-19-7. Molecular formula: C26H26N4O3. Mole weight: 442.519. | |
| Go 6983 | Go 6983 (GOE 6983, Gö 6983) is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ and PKCδ with IC50 of 7 nM, 7 nM, 6 nM and 10 nM, respectively; less potent to PKCζ and inactive to PKCμ. Group: Inhibitors. Alternative Names: GOE 6983, Gö 6983. CAS No. 133053-19-7. Pack Sizes: 10mg. Product ID: S2911. Formula: C26H26N4O3. Smiles: CN(C)CCCN1C=C(C2=C1C=CC(=C2)OC)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54. Storage Conditions: 2 years -80 in solvent. | United States; Europe |
| Go 6983 | Go 6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ, PKCδ and PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gö 6983; Goe 6983. CAS No. 133053-19-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13689. | |
| Goadsporin | It is produced by the strain of Streptomyces sp. TP-A0584. It can promote the secondary metabolism and morphogenesis of Streptomyces, and it is a tool to analyze the regulatory mechanism of Streptomyces. CAS No. 883434-90-0. Molecular formula: C72H97N19O20S2. Mole weight: 1612.78. | |
| Goat's Rue Herb Powder | Goat's Rue Herb Powder. |  CA, FL & NJ |
| GoatThroat Pump EPDM Seal GT200 | The GoatThroat GT200 is a pump for liquid transferring that has a EPDM (Ethylene Propylene Diene Monomer) seal. Pumps help workers stay safe by reducing or completely eliminating spills. GoatThroat pumps are compatible with many different chemicals and viscosities. This durable pump will last you a long time if properly used. Uses: Transfer of liquids. Grades: Food Grade. Pack Sizes: 1. Categories: Goat Throat pumps. |  USA |
| GoatThroat Pump Nitrile Seal GT100 | The GoatThroat GT100 is a pump for transferring liquids that has a nitrile seal. Depending on the viscosity of the liquid, this pump can dispense 4 gallons every minute. Just like gloves or goggles, an effective pump can be one of the best pieces of PPE in the workplace. GoatThroat pumps are known for their durability over time and consistent safe usage. Uses: Transfer of liquids. Grades: Food Grade. Pack Sizes: 1. Categories: Goat Throat pumps. | USA |
| GoatThroat Pump Viton Seal GT300 | The GoatThroat GT300 is a pump for transferring different kinds of liquids that has a viton seal. It can fit almost any container from a 2-gallon jug to a 55-gallon drum. Dispensing is as easy as turning on a faucet! GoatThroat pumps are some of the best, safest, most efficient, and affordable pumps out there. Uses: Transfer of liquids. Grades: Food Grade. Pack Sizes: 1. Categories: Goat Throat pumps. | USA |
| Gocatamig | HY-P990920 is an CD3E/ALB/DLL3-targeting (scFv-heavy-lamdba)-VH-VH' type chimeric humanized antibody[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-6070; HPN328. CAS No. 2851862-91-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990920. | |
| Goitrin | Goitrin. Group: Biochemicals. CAS No. 13190?-?34?-?6?. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| Goji Berry Extract | Goji berry extract is prepared from Lycium chinense, common plants of eastern Asia. Goji berry extract also known as wolfberry extract is rich of polysaccharides, all kinds of vitamins and 19 kinds of amino acid, as well as 21 kinds of minerals. Goji berry extract powder has the functions of preventing & curing cancers, strengthening hematopoiesis, nourishing liver, lowering blood pressure and promoting cell activity. Goji berry extract powder has been widely used in pharmacy manufacture and healthy food processing. Group: Others. Goji Berry Extract; Lycium Chinense Miller. Cat No: EXTC-005. |  |
| Goji Berry Powder | Goji berry juice powder also called wolfberry powder, is a bright orange fine powder that comes from a shrub fresh goji berry that is native to China. Goji berry juice powder is used to treat many common health problems, like diabetes, high bloood pressure, fever, and age reated eye problems. Goji berry Powder is a rich source of nutrients and amino acids. It contains 18 amino acids, 21 trace miner also several vitamins and minerals. Group: Others. Goji Berry Powder; Lycium barbarum L. Cat No: EXTC-086. | |
| Goji Extract (Ratio) | Goji Extract (Ratio). Group: Others. Purity: 4:1~20:1. Goji Extract (Ratio). Cat No: EXTW-036. | |
| Golcadomide | Golcadomide (CC-99282) is a potent and orally active CRBN E3 ligase modulator (CELMoD). Golcadomide interacts with the CRL4 CRBN E3 ubiquitin ligase substrate receptor CRBN, inducing the recruitment and ubiquitin-mediated proteasomal degradation of the transcription factors Ikaros and Aiolos. Golcadomide shows potential for research in cancer-related fields, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-99282. CAS No. 2379572-34-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146237. | |
| Gold | insulated wire, 1m, conductor diameter 0.025mm, insulation thickness 0.002mm, PTFE (polytetrafluoroethylene) insulation, 99.99%. Alternative Names: Gold Powder,Gold black,Gold element. CAS No. 7440-57-5. Molecular formula: Au;Au. Mole weight: 196.97. IUPAC Name: gold. SMILES: [Au]. InChI: 1S/Au. |  |
| Gold (Au) | Gold (Au). Alternative Names: High Purity Gold (Au); 99.99% Gold (Au); 99.999% Gold (Au); 99.9999% Gold (Au). Purity: 4N-6N. | |
| Gold (Au) Evaporation Material | Gold (Au) Evaporation Material. Alternative Names: Au Pellets, Au Wire, Au Pieces, Gold Pellets, Gold Wire, Gold Pieces, Gold Evaporation Material, Au Evaporation Material, Au Evapor Materials, Gold Evapor Materials. Purity: 99.99%. | |
| Gold/Au Nanoparticles | Gold/Au Nanoparticles. | |
| Gold (Au) Sputtering Targets | Gold (Au) Sputtering Targets. Alternative Names: Gold (Au) Sputtering Targets, Au Sputtering Target, Au Sputter Target, Au Target, Gold Sputtering Target, Gold Sputter Target, Gold Target. Purity: 99.99%. | |
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