American Chemical Suppliers

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Product
g-Poly-L-glutamic acid, sodium salt g-Poly-L-glutamic acid, sodium salt. CAS No. 26747-79-0. Product ID: 6-00013. Molecular formula: -[CO(CH2)2CH(CO2H)NH]n. CarboMer Inc
g-Poly-L-glutamic acid, sodium salt g-Poly-L-glutamic acid, sodium salt. CAS No. 26747-79-0. Product ID: 7-00195. Molecular formula: -[CO(CH2)2CH(CO2Na)NH]n. Mole weight: Purity: monodisperse fractions, available in different molecular weights. Properties: temperature threshold: 30°C. CarboMer Inc
GPP 78 GPP 78 is a potent inhibitor of Nicotinamide phosphoribosyltransferase (Nampt) with an IC50 value of 3 nM. Synonyms: CAY10618; NMPRTase Inhibitor; N-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)-1H-1,2,3-triazole-1-octanamide. Grades: ≥95%. CAS No. 1202580-59-3. Molecular formula: C27H29N5O. Mole weight: 439.6. BOC Sciences 10
GPP 78 hydrochloride GPP 78 hydrochloride is an inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), which is subsequently converted to NAD+. It was shown to induce autophagy in neuroblastoma cells. Synonyms: GPP 78 hydrochloride; GPP78 hydrochloride; GPP-78 hydrochloride; N-[1,1'-Biphenyl]-2-yl-4-(3-pyridinyl)-1H,1,2,3-triazole-1-octanamide hydrochloride. Grades: ≥98% by HPLC. Molecular formula: C27H29N5O.HCl. Mole weight: 476.01. BOC Sciences 10
GPP 78 hydrochloride GPP 78 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
GppNH2 GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPN; Guanosine-5'-(β-amino)-diphosphate. Grades: ≥ 95 % by HPLC. Molecular formula: C10H16N6O10P2. Mole weight: 442.21. BOC Sciences 2
GppNHp - Tetralithium salt The tetrasodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Tetralithium salt; GMPPNHP. Grades: ≥ 95 % by HPLC. CAS No. 64564-03-0. Molecular formula: C10H13N6ONa413P3. Mole weight: 611.13. BOC Sciences 2
GppNHp - Trisodium salt The trisodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Trisodium salt; GMPPNHP. Grades: ≥ 90 % by HPLC. CAS No. 148892-91-5. Molecular formula: C10H14N6Na3O13P3. Mole weight: 588.14. BOC Sciences 3
GPR109b Agonist (1-(iso-Propyl)-1H-benzotriazole-5-carboxylic Acid) A cell-permeable Niacin triazolo derivative that acts as a potent and selective agonist toward the human orphan G-protein-coupled receptor GPR109b/HM74, but not GPR109a/HM74A or b-adrenergic receptor. Effectively inhibits cAMP elevation induced by forskolin (5uM) and isoproterenol (1uM), respectively, in GPR109b-expressing CHO cells (EC50=400nM) and freshly isolated human adipocytes (EC50 about 1uM). Group: Biochemicals. Grades: Highly Purified. CAS No. 306935-41-1. Pack Sizes: 25mg. US Biological Life Sciences. USBiological 4
Worldwide
GPR119 Agonist, AS1269574 (G-Protein Coupled Receptor 119 Agonist, 2-((2-(4-Bromophenyl)-6-methylpyrimidin-4-yl)amino)ethanol, GPCR2 Agonist, MGC119957 Agonist, SNORF25 Agonist) A pyrimidine compound that acts as an effective GPR119 agonist (EC50=2.5uM in stimulating cAMP in hGPR119-expressing HEK293 cells) and reportedly exhibits no activity toward B-adrenergic or GLP-1 receptors. Shown to enhance 16.8mM glucose-induced insulin secretion from murine MIN-6 B-cells (mU/20 min=0.44 and 0.22, respectively, with or without 10uM AS1269574) in vitro and improve glucose tolerance in normal mice (100mg/kg; p.o.) without any significant hypoglycemic effect in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 330981-72-1. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
GPR120-IN-1 GPR120-IN-1, a cell-permeable azaspiroundecanyl acetic acid compound, is an orally available, selective agonist of GPR120 (EC50 = ~0.35 μM) that demonstrates potent selectivity over another lipid-sensing G-protein, GPR40 (FFAR1). Synonyms: 2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid; GPR120 Compound A; MDK77754; MDK-77754; MDK 77754; GPR120 cpdA. CAS No. 1599477-75-4. Molecular formula: C19H23ClF3NO3. Mole weight: 405.84. BOC Sciences 10
GPR120 modulator 1 GPR120 modulator 1 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 1; 1050506-75-6; 2-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenoxy]acetic acidAcetic acid, 2-[4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methylphenoxy]-GPR120-modulator-1. Grades: >98%. CAS No. 1050506-75-6. Molecular formula: C19H16ClNO4S. Mole weight: 389.85. BOC Sciences 10
GPR120 modulator 2 GPR120 modulator 2 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 2; 1050506-87-0; 3-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenyl]propanoic acidBenzenepropanoic acid, 4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methyl-3-(4-{[4-(2-CHLOROPHENYL)-1,3-THIAZOL-2-YL]METHOXY}-2-METHYLPHENYL)PROPANOIC ACID. Grades: >98%. CAS No. 1050506-87-0. Molecular formula: C20H18ClNO3S. Mole weight: 387.88. BOC Sciences 10
GPR139 agonist-2 GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC 50 of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2983118-29-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-149651. MedChemExpress MCE
GPR183-IN-2 GPR183-IN-2 (compound 23) is a potent GPR183 inhibitor. GPR183-IN-2 inhibits Ca 2+ mobilization with an IC 50 value of 39.45 nM. GPR183-IN-2 has the potential for the research of cancer, autoimmune diseases, pain, and osteoporosis [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2924064-10-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163796. MedChemExpress MCE
GPR34 receptor antagonist GPR34 receptor antagonist Inhibitor. Uses: Scientific use. Product Category: T8848. CAS No. 907952-06-1. TARGETMOL CHEMICALS
GPR35 agonist 5 GPR35 agonist 5 (3,5-dinitro-bisphenol A; compound 6) is a weak GPR35 agonist. GPR35 agonist 5 arrests CHO-S cells at the G1/Gophase [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2226201-24-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149190. MedChemExpress MCE
GPR40 Activator 1 GPR40 Activator 1 is a potent GPR40 activator for treatment of type 2 diabetes. Synonyms: GPR40 Activator 1. Grades: >98%. CAS No. 1309435-60-6. Molecular formula: C31H31NO3S. Mole weight: 497.65. BOC Sciences 10
GPR40 Activator 2 GPR40 Activator 2 is a potent GPR40 activator from patents WO 2012147516 A1, WO 2012046869A1 and WO 2011078371 A1. Synonyms: GPR40 Activator 2. Grades: >98%. CAS No. 1312787-30-6. Molecular formula: C28H29NO6S2. Mole weight: 539.66. BOC Sciences 10
GPR40 Agonist II (FFA1 Agonist II, Free Fatty Acid Receptor 1 Agonist II, 3- (4- ( (2, 6-Dichloropyridin-4-yl) ethynyl) phenyl) propanoic Acid) A cell-permeable alkynedihydrocinnamic acid that acts as a potent GPR40/FFA1 agonist (EC50=40.7nM in inducing Ca2+ mobilization in hFFA1-expressing 1321N1 cells) with >100-fold selectivity over GPR43/FFA2, GPR41/FFA3, and a panel of 56 other receptors, ion channels, and transporters. Reported to enhance 12mM glucose-induced insulin secretion from rat INS-1E B-cells (by 34% at 10uM) and exhibit good aqueous solubility (199uM in PBS at pH 7.4), as well as chemical and metabolic stability. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
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GPR43 (FFA2) Agonist ((S)-2-(4-chlorophenyl)-3,3-dimethyl-N-(5-phenylthiazol-2-yl)butanamide) A phenylacetamide compound that acts as an allosteric agonist of FFA2 (GPR43), demonstrating a left-shifted acetate dose response (IC50=0.7uM) and 111% efficacy relative to acetate in hFFA2 forskolin-induced cAMP assays. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
GPR55 agonist 3 GPR55 agonist 3 (Compound 26) is a GPR55 agonist ( EC 50 : 0.239 nM, and 1.76 nM for hGPR55 and rGPR55). GPR55 agonist 3 induces β-arrestin recruitment to human GPR55 ( EC 50 : 6.2 nM) [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 3006105-44-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156107. MedChemExpress MCE
GPR55 Receptor Antagonist, CID16020046 (4-[4-(3-Hydroxyphenyl)-3-(4-methylphenyl)-6-oxo-1H,4H-pyrrolo[3,4-c]pyrazol-5-yl]benzoic Acid) A selective antagonist of G protein-coupled receptor 55 (GPR55) that blocks lipid L-a-lysophosphatidyl inositol (LPI)-induced GPR55 activation (IC50 = 1uM) and downstream effects in HEK293 cells. Also shown to block the agonistic effect of LPI on GPR55- expressing yeast cells (~10uM). Inhibits LPI-induced Ca2+ mobilization and ERK1/2 phosphorylation in HEK-GPR55 and HEK-CB1 cells. However, it does not affect basal Ca2+ mobilization and ERK1/2 activity. Blocks the GPR55-mediated NFAT and NF-kB activation and their nuclear translocation in HEK-GPR55 cells. Diminishes LPI-induced wound healing in GPR55-expressing primary human lung microvascular endothelial cells and reverses LPI-inhibited platelet aggregation (~10uM). Also reported to inhibit the activity of phosphodiesterases PDE3A and PDE4B (pIC50 = 5 and 4.8, respectively). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?. US Biological Life Sciences. USBiological 4
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GPR81 Agonist, 3Cl-5OH-BA (3-Chloro-5-hydroxybenzoic Acid, Hydroxycarboxylic Acid Receptor 1 Agonist) A hydroxybenzoic acid compound that acts as a GPR81/HCA1-selective agonist (EC50 ~7, 16, 17, 22, and 67uM toward rat, human, monkey, mouse, and dog species, respectively) with little activity towards the homologous GPR109A/HCA2/HM74A GPCR. Orally active in mice and exhibits NEFAc cholesterol-lowering efficacy in overnight fasted C57B16/J mice (ED50 ~100mg/kg, p.o.) in vivo. Group: Biochemicals. Grades: Highly Purified. CAS No. 53984-36-4. Pack Sizes: 100mg. US Biological Life Sciences. USBiological 4
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gpr endopeptidase Initiates the degradation of small, acid-soluble proteins during spore germination in Bacillus megaterium. Type example of peptidase family M63. Group: Enzymes. Synonyms: germination proteinase. Enzyme Commission Number: EC 3.4.24.78. CAS No. 75718-32-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4362; gpr endopeptidase; EC 3.4.24.78; 75718-32-0; germination proteinase. Cat No: EXWM-4362. Creative Enzymes
G-Protein antagonist peptide G-Protein antagonist peptide is a competitive and reversible inhibitor of M2 muscarinic cholinergic receptors. G-Protein antagonist peptide inhibits M2 muscarinic receptor activation of Gi or Go and suppresses Gs activation by β-adrenoceptors. Synonyms: GPAnt-2; G Protein Antagonist. Grades: >98%. CAS No. 143675-79-0. Molecular formula: C57H64N12O9S. Mole weight: 1093.27. BOC Sciences 3
G-protein-coupled receptor kinase Requires G-protein for activation and therefore belongs to the family of G-protein-dependent receptor kinases (GRKs). All members of this enzyme subfamily possess a highly conserved binding site for 1-phosphatidylinositol 4,5-bisphosphate. (cf. EC 2.7.11.14, rhodopsin kinase and EC 2.7.11.15, β-adrenergic-receptor kinase). Group: Enzymes. Synonyms: G protein-coupled receptor kinase; GPCR kinase; GPCRK; GRK4; GRK5; GRK6; STK16. Enzyme Commission Number: EC 2.7.11.16. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3135; G-protein-coupled receptor kinase; EC 2.7.11.16; G protein-coupled receptor kinase; GPCR kinase; GPCRK; GRK4; GRK5; GRK6; STK16. Cat No: EXWM-3135. Creative Enzymes
GPRP GPRP is an inhibitor of fibrin polymerization. It binds to fibrinogen (Ki = 400 mM). Synonyms: Gly-pro-arg-pro; L-Proline,glycyl-L-prolyl-L-arginyl-; (S)-1-((S)-2-((S)-1-(2-aminoacetyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxylic acid. CAS No. 67869-62-9. Molecular formula: C18H31N7O5. Mole weight: 425.48. BOC Sciences 6
GPX100 GPX-100 is an analogue of the anthracycline antineoplastic antibiotic doxorubicin. GPX-100 intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. GPX-100 was designed to be a non-cardiotoxic anthracycline antibiotic. Synonyms: Epirubicin Impurity 1; 13-Deoxyepirubicin; GPX 100; GPX-100; 13-deoxy-doxorubicin; (1S,3R)-3,5,12-Trihydroxy-3-(2-hydroxyethyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranoside; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyethyl)-1-methoxy-, (8R,10S)-. Grades: ≥95%. CAS No. 952648-77-0. Molecular formula: C27H31NO10. Mole weight: 529.54. BOC Sciences 11
GPX150 GPX-150 is a synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Anthracycline analogue GPX-150 intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis. Synonyms: GPX 150; GPX-150; 5(8H)-Naphthacenone, 10-((3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy)-7,9,10,12-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyethyl)-12-imino-1-methoxy-, (8R,10S)-. CAS No. 236095-29-7. Molecular formula: C27H32N2O9. Mole weight: 528.56. BOC Sciences 11
GQ-16 GQ-16 is a moderate affinity ligand for the ligand-binding domain (LBD) of PPARγ , exhibiting a K i of 160 nM. GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation of PPAR&gamma. GQ-16 is a partial agonist of PPARγ with reduced adipogenic actions. GQ-16 promotes insulin Sensitization without weight gain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 870554-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111254. MedChemExpress MCE
GQ-16 GQ-16 is an effective and partial agonist for peroxisome proliferator-activated receptor γ (PPARγ) (Ki = 160 nM). It does not activate PPARα, PPARβ/δ, or RXR&alpha. Synonyms: 5Z-[(5-bromo-2-methoxyphenyl)methylene]-3-[(4-methylphenyl)methyl]-2,4-thiazolidinedione. Grades: ≥98%. CAS No. 870554-67-9. Molecular formula: C19H16BrNO3S. Mole weight: 418.3. BOC Sciences 10
GQ1b-Ganglioside GQ1b-Ganglioside is a vital biomedical product utilized for its neuroprotective properties. This compound acts as a crucial element in the treatment of various neurological disorders, including Guillain-Barré syndrome and Miller Fisher syndrome. Synonyms: Tetrasialoganglioside 1b. CAS No. 68652-37-9. Molecular formula: C106H182N6O56 4H3N. Mole weight: 2504.71. BOC Sciences 12
GQ3-Oligosaccharide GQ3-Oligosaccharide is an extraordinary bioactive compound employed in the research of neurodegenerative ailments, showcasing remarkable neuroprotective attributes. GQ3-Oligosaccharide actively contributes to the diminution of oxidative stress and inflammation, thereby facilitating the augmentation of neuronal viability and efficacious functioning. Synonyms: Neu5Aca2-8Neu5Aca2-8Neu5Acb2-8Neu5Aca2-3Galb1-4Glc. Molecular formula: C56H86N4O43Na4. Mole weight: 1595.24. BOC Sciences 12
GR 103691 GR 103691 is a potent dopamine D3 receptor antagonist. Uses: Dopamine antagonists. Synonyms: GR 103691; GR103691; GR-103691; 4'-Acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-[1,1'-biphenyl]-4-carboxamide. Grades: 99%. CAS No. 162408-66-4. Molecular formula: C30H35N3O3. Mole weight: 485.62. BOC Sciences 10
GR 113808 GR 113808 is a potent and selective 5-HT4 receptor antagonist (pKB = 9.43 in human colonic muscle, Kd=0.15 nM for binding to cloned human 5-HT4 receptors). GR 113808 displays > 300-fold selectivity for 5-HT4 over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. Uses: Serotonin antagonists. Synonyms: GR 113808; GR113808; GR-113808. 1-methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester. Grades: ≥98% by HPLC. CAS No. 144625-51-4. Molecular formula: C19H27N3O4S. Mole weight: 393.5. BOC Sciences 10
GR 113808 GR 113808 is a potent and highly selective 5-HT 4 receptor antagonist ( pK b = 8.8). GR 113808 shows 300-fold selectivity over 5-HT 1A , 5-HT 1B , 5-HT 2A , 5-HT 2C and 5-HT 3 receptors [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 144625-51-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103152. MedChemExpress MCE
GR113808 (5-HT4 Serotonin Receptor Antagonist, GR113808, GR 113808, GR-113808) A potent and selective antagonist of the serotonin 5-HT4 receptor (pki = 9.3-10.3). GR113808 is commonly used in brain and peripheral in vitro and in vivo in striatum studies (Guinea pig IC50 = 113nM, rat brain membrane Kd = 0.4-1nM) and in cAMP response in CHO and C6 glial cells (EC50 = 79-81nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 144625-51-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences. USBiological 4
Worldwide
GR 125487 sulfamate GR 125487, a potent and selective 5-HT4 antagonist, is used in many biological assays to cross confirm the 5-HT4R agonist's activity. Synonyms: GR 125487 sulfamate; GR 125487; GR125487; GR-125487. 5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylate sulfamate. Grades: ≥97% by HPLC. CAS No. 859502-43-5. Molecular formula: C19H26FN3O5S.H2NSO3H. Mole weight: 524.58. BOC Sciences 10
GR 127935 hydrochloride GR 127935 hydrochloride is a potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors), exhibiting > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Synonyms: [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, hydrochloride (1:1); [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, monohydrochloride; N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxamide hydrochloride; GR127935 hydrochloride; GR-127935 hydrochloride. Grades: ≥99% by HPLC. CAS No. 148642-42-6. Molecular formula: C29H31N5O3.HCl. Mole weight: 534.06. BOC Sciences 10
GR127935 hydrochloride GR127935 hydrochloride is a potent and orally active 5-HT1D and 5-HT1B receptor antagonist with pKis of 8.5 for both isoforms. GR127935 hydrochloride has 100-fold selectivity for 5-HT1B/1D receptors over 5-HT1A, 5-HT2A, and 5-HT2C receptors. GR127935 hydrochloride can be used in neurological disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148642-42-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100794. MedChemExpress MCE
GR 127935 Hydrochloride (5-HT1B/1D Serotonin Receptor Antagonist, GR 127935 Hydrochloride, GR-127935 Hydrochloride, GR127935 Hydrochloride) A selective 5-HT1B/1D receptor antagonist. Selectivity was found to be similar for B (pki = 9.2-9.8) and D (pki = 8.6-9.1) receptor types. GR 127935 works well in vivo and was shown to block (+)-MDMA-induced hyperactivity in rats. It alters release of serotonin in the brain, as well as reducing drug-seeking behavior in cocaine addicted rats. In transformed rat C5 glioma cells, this inhibitor blocked 5HT with an IC50 = 97pM. Group: Biochemicals. Grades: Highly Purified. CAS No. 148642-42-6. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences. USBiological 4
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GR 135402 A novel antifungal antibiotic GR 135402 has been isolated from a Graphium putredinis which inhibited protein synthesis in Candida albicans but not rabbit reticulocytes. Synonyms: Antibiotic GR135402; GR135402. CAS No. 204199-15-5. Molecular formula: C34H48O9. Mole weight: 600.74. BOC Sciences 5
GR 135531 GR 135531 is a high affinity agonist of MT3 melatonin receptors, with low affinity for MT1 and MT2 melatonin receptors. GR 135531 can be used to discriminate between the melatonin receptor subtypes. Synonyms: GR 135531; GR135531; GR-1355315-Methoxycarbonylamino-N-acetyltryptamine; 5-MCA-NAT; methyl N-[3-(2-acetamidoethyl)-1H-indol-5-yl]carbamate. Grades: ≥97% by HPLC. CAS No. 190277-13-5. Molecular formula: C14H17N3O3. Mole weight: 275.31. BOC Sciences 10
GR 135531 GR 135531. Group: Biochemicals. Grades: Purified. CAS No. 190277-13-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
GR 144053 trihydrochloride GR 144053 trihydrochloride is a potent and selective orally bioactive platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist (IC50 = 37 nM). GR 144053 potently inhibits thrombus formation in vivo. Synonyms: GR 144053; GR-144053; GR144053; GR 144053 trihydrochloride. 4-[4-[4-(Aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid trihydrochloride. Grades: ≥99% by HPLC. CAS No. 1215333-48-4. Molecular formula: C18H27N5O2.3HCl. Mole weight: 454.83. BOC Sciences 9
GR 144053 trihydrochloride GR 144053 trihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1215333-48-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
GR 159897 GR 159897 is a potent and selective neurokinin NK2 receptor antagonist. GR 159897 competes for binding of [3H]GR100679 to hNK2-transfected CHO cells (pKi = 9.5). Study shows that GR 159897 inhibits NK2 receptor-mediated contraction of guinea pig trachea. Synonyms: GR 159897; GR159897; GR-159897; 5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole. Grades: ≥97% by HPLC. CAS No. 158848-32-9. Molecular formula: C23H27FN2O2S. Mole weight: 414.54. BOC Sciences 10
GR 203040 GR 203040 is a selective NK1 receptor antagonist with high affinity. GR 203040 potently inhibits substance P binding to NK1 receptors (pKi = 10.1 to 10.5). Synonyms: (2S,3S)-N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride. Grades: ≥98% by HPLC. CAS No. 168398-02-5. Molecular formula: C20H24N6O·2HCl. Mole weight: 437.37. BOC Sciences 9
GR 231118 GR 231118. Group: Biochemicals. Grades: Purified. CAS No. 158859-98-4. Pack Sizes: 500ug. US Biological Life Sciences. USBiological 5
Worldwide
GR 231118 GR 231118 is a potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1 receptors, respectively) and an NPY Y4 receptor agonist (pEC50 = 6.0, 8.6 and 6.1 for rY2, hY4 and rY5 receptors, respectively). GR 231118 inhibits food intake in rats in vivo. Synonyms: GR-231118; GR 231118; GR231118. Grades: >99%. CAS No. 158859-98-4. Molecular formula: C110H170N34O24. Mole weight: 2352.77. BOC Sciences 3
GR24 (Rac)-GR24 (Strigolactone GR24) is a plant hormone analog. (Rac)-GR24 can mimic the natural germination stimulus of parasitic plant seeds, promoting seed germination in the absence of host plants, thereby reducing the number of parasitic seeds in the soil. (Rac)-GR24 can be used in agricultural research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Strigolactone GR24. CAS No. 76974-79-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-129038. MedChemExpress MCE
GR 46611 GR 46611 is a 5-HT1D receptor agonist that may be beneficial for the treatment of migraine. 5-HT1D acts on the central nervous system. Synonyms: GR 46611; GR46611; GR-46611; 3-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-(4-methoxybenzyl)acrylamide. CAS No. 185259-85-2. Molecular formula: C23H27N3O2. Mole weight: 377.49. BOC Sciences 10
GR 49336 A metabolite of Sumatriptan. Group: Biochemicals. Alternative Names: 5-[[ (Methylamino) sulfonyl]methyl]-. Grades: Highly Purified. CAS No. 103628-44-0. Pack Sizes: 2.5mg. US Biological Life Sciences. USBiological 2
Worldwide
GR 49336 GR 49336. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-[[(Methylamino)sulfonyl]methyl]-1H-indole-3-acetic Acid. Product Category: Heterocyclic Organic Compound. CAS No. 103628-44-0. Molecular formula: C12H14N2O4S. Mole weight: 282.32. Purity: 0.96. IUPACName: 2-[5-(methylsulfamoylmethyl)-1H-indol-3-yl]acetic acid. Canonical SMILES: CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CC(=O)O. Density: 1.471g/cm³. Product ID: ACM103628440-1. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
GR5 Synonyms: (E)-3-(((4-methyl-5-methylene-2,5-dihydrofuran-2-yl)oxy)methylene)dihydrofuran-2(3H)-one. Grades: >95% by HPLC. BOC Sciences 6
GR 55562 dihydrochloride GR 55562 dihydrochloride is a selective and competitive 5-HT1B (5-HT1Dβ) silent antagonist (pKB values of 7.3 and 6.3 for human cloned 5-HT1B and 5-HT1D receptors, respectively). Synonyms: GR 55562 dihydrochloride; GR-55562; GR55562; GR 55562. 3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride. Grades: ≥98% by HPLC. CAS No. 159533-25-2. Molecular formula: C23H25N3O2.2HCl. Mole weight: 448.39. BOC Sciences 10
GR 55562 hydrochloride GR 55562 hydrochloride is a selective 5-HT 1B receptor antagonist. GR 55562 hydrochloride can be used for the research of nerve disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 172854-55-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W010869. MedChemExpress MCE
GR 64349 GR 64349 is a potent and selective agonist of tachykinin NK2 receptor (EC50 = 3.7 nM in rat colon). Synonyms: GR 64349; GR64349; GR-64349; LYS-ASP-SER-PHE-VAL-GLY-R-GAMMA-LACTAM-LEU-MET-NH2; [LYS3, GLY8-R-GAMMA-LACTAM-LEU9]NEUROKININ A (3-10); L-Lys-L-Asp-L-Ser-L-Phe-L-Val-N-[(3R)-1-[(R)-1-[[[(S)-1-(Aminocarbonyl)-3-(methylthio)propyl]amino]carbonyl]-3-methylbutyl]-2-oxo-3α-pyrrolidi. Grades: >98%. CAS No. 137593-52-3. Molecular formula: C42H68N10O11S. Mole weight: 921.12. BOC Sciences 9
GR 73632 GR 73632 is a potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens). GR 73632 is able to be used in the treatment of asthma and gastrointestinal disorders. Synonyms: GR-73632; GR 73632; GR73632. Delta-Aminovaleryl-9-pro-10-meleu-substance P (7-10); Substance P (7-10), delta-aminovaleryl-pro(9)-N-meleu(10)-; Substance P (7-10), delta-aminovaleryl-prolyl(9)-N-methylleucine(10)-. CAS No. 133156-06-6. Molecular formula: C40H59N7O6S. Mole weight: 766.01. BOC Sciences 3
GR 79236 GR 79236, an effective Adenosine A1 receptor agonist, could probably be used as an anti-inflammatory agent. IC50: 3.1 nM(Ki). Uses: Gr 79236 is an effective adenosine a1 receptor agonist that could probably be used as an anti-inflammatory agent. Synonyms: GR79236; GR-79236; GR 79236. N-[(1S, trans)-2-Hydroxycyclopentyl]adenosine. Grades: 95%. CAS No. 124555-18-6. Molecular formula: C15H21N5O5. Mole weight: 351.36. BOC Sciences 10
GR 82334 GR 82334 is a tachykinin NK1 receptor antagonist. Synonyms: GR-82334; GR 82334; GR82334; Physalaemin(1-11), D-pro(9)(spiro-gamma-lactam)leu(10)-trp(11)-; Physalemin, 9-deglycine-10-((5S)-6-oxo-L-alpha-(2-methylpropyl)-1,7-diazaspiro(4.4)nonane-7-acetic acid)-11-L-tryptophanamide-. Grades: >98%. CAS No. 129623-01-4. Molecular formula: C69H91N15O16. Mole weight: 1386.57. BOC Sciences 3
GR 89696 GR 89696 is a highly selective κ2 opioid receptor agonist with potential to prevent pruritus [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 126766-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-107747. MedChemExpress MCE
GR 89696 fumarate GR 89696 fumarate is a potent and selective κ-opioid agonist (IC50 = 0.04 nM) displaying anti-nociceptive and neuroprotective activity. Synonyms: GR 89696 fumarate; GR 89696; GR89696; GR-89696. 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate. Grades: ≥99% by HPLC. CAS No. 126766-32-3. Molecular formula: C19H25Cl2N3O3.C4H4O4. Mole weight: 530.4. BOC Sciences 10
GR 89696 fumarate GR 89696 fumarate. Group: Biochemicals. Grades: Purified. CAS No. 126766-32-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
GR 94800 GR 94800 is a potent and selective tachykinin NK2 receptor antagonist (pKB = 9.6, 6.4 and 6.0 for NK2, NK1 and NK3 receptors, respectively). Synonyms: N-Benzoyl-L-alanyl-L-alanyl-D-tryptophyl-L-phenylalanyl-D-prolyl-L-prolyl-L-norleucinamide. Grades: >98%. CAS No. 141636-65-9. Molecular formula: C49H61N9O8. Mole weight: 904.08. BOC Sciences 3
Gracillin Gracillin. Group: Biochemicals. Grades: Plant Grade. CAS No. 19083-00-2. Pack Sizes: 10mg. Molecular Formula: C45H72O17, Molecular Weight: 885.04. US Biological Life Sciences. USBiological 9
Worldwide
GRA Ex-25 GRA Ex-25 is an orally active human glucagon receptor antagonist in a transgenic murine pharmacodynamic model, with IC50 of 56 and 55 nM for rat and human glucagon receptors, respectively. GCGR has evolved as an attractive therapeutic target for the treatment of type II diabetes mellitus. Synonyms: 3- (4- ( (1- (4- (tert-butyl) cyclohexyl) -3- (4- (trifluoromethoxy) phenyl) ureido) methyl) benzamido) propanoic acid; GRA Ex-25; GRA Ex 25; GRA Ex25; GRAEx-25; GRAEx 25; GRAEx25. CAS No. 307983-31-9. Molecular formula: C29H36F3N3O5. Mole weight: 563.61. BOC Sciences 10
Grafoil Synthetic Thermal Graphite Film Grafoil Synthetic Thermal Graphite Film. Group: Pyrolitic graphite. Alfa Chemistry Materials 3
Grahamimycin B It is produced by the strain of Cytospora sp. W. F. P. L. 13A (ATCC20502). It has weak activity against gram-positive bacteria, negative bacteria, cyanobacteria and green algae. Synonyms: 1,7-Dioxacyclotetradec-3-ene-2,8,11-trione,9,12-dihydroxy-6,14-dimethyl-, (6R-(3E,6R*,9R*,12R*,14S*))-. CAS No. 75979-94-1. Molecular formula: C14H20O7. Mole weight: 300.30. BOC Sciences 5

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