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| Product | Description | |
|---|---|---|
| Gly-Val-Leu | Gly-Val-Leu is a tripeptide composed of glycine, L-valine, and L-leucine. Glycine is the simplest amino acid, contributing to protein structure and neurotransmitter functions. L-valine and L-leucine are branched-chain amino acids (BCAAs) crucial for muscle protein synthesis, energy production, and recovery. This tripeptide may have roles in metabolic processes, muscle growth, and protein interactions, making it relevant for studies in nutrition, muscle physiology, or therapeutic peptide design. Synonyms: GVL; N-(N-Glycyl-L-valyl)-L-leucine; Glycyl-L-valyl-L-leucine; Glycyl-valyl-leucine; H-Gly-Val-Leu-OH; H-GVL-OH. Grade: ≥90%. CAS No. 97812-05-0. Molecular formula: C13H25N3O4. Mole weight: 287.36. |  |
| Gly-Val-OH HCl | Gly-Val-OH HCl. Synonyms: Glycyl-L-valine hydrochloride. Grade: ≥ 98%. Molecular formula: C7H14N2O3·HCl. Mole weight: 210.7. | |
| Gly-Val-OH·HCl 99+% (HPLC) | Gly-Val-OH·HCl 99+% (HPLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g, 100g. US Biological Life Sciences. |  Worldwide |
| Gly-Val-Val | Gly-Val-Val is a tripeptide composed of glycine and two L-valine residues. Glycine supports protein synthesis and central nervous system function, while L-valine, a branched-chain amino acid (BCAA), is essential for muscle repair, energy production, and maintaining muscle mass. This peptide may enhance muscle recovery and support metabolic processes, making it potentially useful in contexts requiring muscle maintenance and energy support. Synonyms: GVV; Glycyl-L-valyl-L-valine; Glycyl-valyl-valine; H-Gly-Val-Val-OH; H-GVV-OH; L-Valine, N-(N-glycyl-L-valyl)-. Grade: ≥90%. CAS No. 79672-11-0. Molecular formula: C12H23N3O4. Mole weight: 273.33. | |
| GLYX13 | GLYX13. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Rapastinel Trifluoroacetate. Appearance: White crystalline. CAS No. 1435786-04-1. Molecular formula: C20H32F3N5O8. Mole weight: 527.5. Purity: 0.99. Product ID: ACM1435786041. Alfa Chemistry ISO 9001:2015 Certified. Categories: GLYX-13. |  |
| GLYX 13 | GLYX 13. Group: Biochemicals. Grades: Purified. CAS No. 117928-94-6. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| GLYX-13 trifluoroacetate | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. |  |
| Gly-Xaa carboxypeptidase | From yeast. In peptidase family M20 (glutamate carboxypeptidase family). Group: Enzymes. Synonyms: glycine carboxypeptidase; carboxypeptidase a; carboxypeptidase S; peptidase α; yeast carboxypeptidase; Gly-X carboxypeptidase. Enzyme Commission Number: EC 3.4.17.4. CAS No. 9025-25-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4078; Gly-Xaa carboxypeptidase; EC 3.4.17.4; 9025-25-6; glycine carboxypeptidase; carboxypeptidase a; carboxypeptidase S; peptidase α; yeast carboxypeptidase; Gly-X carboxypeptidase. Cat No: EXWM-4078. |  |
| GM 1489 | GM 1489 is a potent broad-spectrum inhibitor of matrix metalloproteinases (MMPs) with Ki values of 0.002, 0.1, 0.5, 0.2, and 20 μM for MMP-1, MMP-8, MMP-2, MMP-9, and MMP-3, respectively. Synonyms: Hexanoic acid, 3-[[[(1S)-1-(1H-indol-3-ylmethyl)-2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]carbonyl]-5-methyl-, (3R)-; (3R)-3-[[[(1S)-1-(1H-Indol-3-ylmethyl)-2-oxo-2-[[(1S)-1-phenylethyl]amino]ethyl]amino]carbonyl]-5-methylhexanoic acid; Hexanoic acid, 3-[[[1-(1H-indol-3-ylmethyl)-2-oxo-2-[(1-phenylethyl)amino]ethyl]amino]carbonyl]-5-methyl-, [3R-[3R*[S*(S*)]]]-; GM-1489; GM1489. Grade: ≥98%. CAS No. 171347-75-4. Molecular formula: C27H33N3O4. Mole weight: 463.57. | |
| GM1a Ganglioside oligosaccharide | GM1a Ganglioside oligosaccharide. Grade: 95%. CAS No. 67063-78-9. Molecular formula: C34H58N2O26. Mole weight: 910.8. | |
| GM1b Ganglioside oligosaccharide | GM1b-Oligosaccharide is an innovative and promising compound, showcasing its potential in studying complex neurodegenerative ailments including Parkinson's and Alzheimer's diseases. Derived from the GM1 ganglioside, this compound offers a remarkable neuroprotective effect by significantly augmenting neuronal survival and effectively thwarting cognitive decline. Molecular formula: C37H61N2O29Na. Mole weight: 1020.87. | |
| GM1-Ganglioside labelled by biotin | GM1-Ganglioside labelled by biotin is a crucial tool for studying neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. This specialized probe facilitates the detection and visualization of GM1-Ganglioside within cells and tissues. Its biotin label enables specific binding to avidin or streptavidin and allowing for further investigation of the role of GM1-Ganglioside in these diseases. Synonyms: N-Hexanoyl-biotin-monosialoganglioside GM1. Molecular formula: C71H122N6O33S. Mole weight: 1619.82. | |
| GM1-Lysoganglioside | GM1-Lysoganglioside, a highly esteemed biomedical agent, stands as a fostering solution amidst the intricate realm of neurodegenerative afflictions like Parkinson's disease and Alzheimer's disease. Synonyms: lyso-Monosialoganglioside GM1; Lyso-GM1; (2S,3R,4E)-2-Amino-3-hydroxy-4-octadecenyl O-(N-acetyl-α-neuraminosyl)-(2→3)-O-[O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)]-O-β-D-galactopyranosyl-(1→4)-β-D-glucopyranoside; β-D-Glucopyranoside, 2-amino-3-hydroxy-4-octadecenyl O-(N-acetyl-α-neuraminosyl)-(2→3)-O-[O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)]-O-β-D-galactopyranosyl-(1→4)-, [R-[R*,S*-(E)]]-. Grade: 95%. CAS No. 94458-59-0. Molecular formula: C55H97N3O30. Mole weight: 1280.36. | |
| GM1-Lysoganglioside potassium salt | GM1-Lysoganglioside potassium salt is a biomedicine utilized in the treatment of neurodegenerative disorders and nerve injuries. It acts as an essential neurotrophic factor in promoting nerve regeneration and maintaining neuronal survival. GM1-Lysoganglioside potassium salt has shown promising results in alleviating symptoms associated with diseases like Alzheimer's and Parkinson's, making it a potential therapeutic option for these conditions. Synonyms: lyso-Monosialoganglioside GM1 potassium salt; β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecen-1-yl O-(N-acetyl-α-neuraminosyl)-(2→3)-O-[O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)]-O-β-D-galactopyranosyl-(1→4)-, potassium salt (1:1); β-D-Glucopyranoside, (2S,3R,4E)-2-amino-3-hydroxy-4-octadecenyl O-(N-acetyl-α-neuraminosyl)-(2→3)-O-[O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)]-O-β-D-galactopyranosyl-(1→4)-, monopotassium salt; β-D-Glucopyranoside, 2-amino-3-hydroxy-4-octadecenyl O-(N-acetyl-α-neuraminosyl)-(2→3)-O-[O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)]-O-β-D-galactopyranosyl-(1→4)-, monopotassium salt, [R-[R*,S*-(E)]]-. CAS No. 171483-40-2. Molecular formula: C55H96KN3O30. Mole weight: 1318. | |
| GM1-Pentasaccharide | GM1-Pentasaccharide, an auspicious compound in the field of biomedicine, holds substantial promise for the management of neurodegenerative ailments. Originating from the ganglioside GM1, this pentasaccharide exhibits remarkable prowess in augmenting neuronal rejuvenation and restoring impaired nerves. By virtue of its neuroprotective attributes, it manifests as an invaluable therapeutic asset for afflictions including Alzheimer's and Parkinson's disease. Synonyms: GM1-oligosaccharide; D-Glucose, O-(N-acetyl-α-neuraminosyl)-(2→3)-O-[O-β-D-galactopyranosyl-(1→3)-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)]-O-β-D-galactopyranosyl-(1→4)-; O-β-D-Galactopyranosyl-(1→3)-O-2-(acetylamino)-2-deoxy-β-D-galactopyranosyl-(1→4)-O-[N-acetyl-α-neuraminosyl-(2→3)]-O-β-D-galactopyranosyl-(1→4)-D-glucose; Galβ1-3GalNAcβ1-4(Neu5Acα2-3)Galβ1-4Glc; GM1OS. CAS No. 52659-37-7. Molecular formula: C37H62N2O29. Mole weight: 998.88. | |
| GM1-Pentasaccharide, APD-HSA conjugate | GM1-Pentasaccharide, APD-HSA conjugate. | |
| GM1-Pentasaccharide labelled by biotin | GM1-Pentasaccharide labelled by biotin is a biotin-labelled compound widely utilized in the biomedical industry for extensive research purposes. Its application predominantly revolves around comprehending the intricate interplay between GM1-Pentasaccharide and specific biomolecules. It facilitates effortless detection and observation via biotin-streptavidin labeling methods. Synonyms: GM1-Pentasaccharide-O(CH2)3NHCO(CH2)5NH-biotin. Molecular formula: C50H83N5O31S. Mole weight: 1282.28. | |
| GM2-Ganglioside | GM2-Ganglioside, a lipid molecule nestled in cellular membranes, has been linked to various pathologies of the central nervous system like Huntington's and Parkinson's disease. By delving into the underlying pathogenesis pathways, GM2-Ganglioside can serve as a potent therapeutic agent. As a clinical ingredient for vaccines against infectious diseases and a potential player in cancer therapy, this nano-molecule is showing promise as a versatile therapeutic option. Synonyms: Monosialoganglioside GM2; b-GalNAc-(1→4)-[a-Neu5Ac-(2→3)]-b-Gal(1→4)-b-Glc-(1→1)-Cer; Ganglioside GM2; Ganglioside A1; Ganglioside G5; Ganglioside GM2; Ganglioside GO; Ganglioside M2; GM2; Sialosylganglio-N-triaosylceramide; Tay-Sachs ganglioside. CAS No. 19600-01-2. | |
| GM2-Oligosaccharide | GM2-Oligosaccharide is a prominent constituent in the realm of biomedical applications, finding extensive utility in the investigation of lysosomal storage disorders. Acting as an invaluable compound in the scientific domain, this oligosaccharide facilitates the exploration of intricate processes underlying GM2 ganglioside metabolism. Synonyms: GM2 Ganglioside oligosaccharide. Molecular formula: C31H51N2O24Na. Mole weight: 858.73. | |
| GM2-Oligosaccharide-spacer-NH2 ammonium | GM2-Oligosaccharide-spacer-NH2 ammonium is a vital compound used in biomedicine. Its application lies in the treatment of GM2 gangliosidoses, a group of genetic disorders caused by the deficiency of vital enzymes. Synonyms: GalNAcb-4(NeuAca2-3)Galb-4Glcb-NAc-spacer-NH2. Molecular formula: C44H75N7O27.NH3. Mole weight: 1151.13. | |
| GM2-Oligosaccharide-sp-biotin | GM2-Oligosaccharide-sp-biotin. | |
| GM3-Ganglioside | GM3-Ganglioside, a renowned biomedical compound, is an exceptional therapeutic agent employed for managing debilitating neurodegenerative conditions, prominently encompassing Alzheimer's disease and Parkinson's disease. Its inherent proficiency in preserving neuronal coherence and functionality renders it indispensable in clinical practice. Synonyms: aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer; Ganglioside GM3; Ganglioside M3; Gangliosides, GM3; GLac1; GM3; Hematoside; Monosialodihexosylganglioside; Sialosyllactosylceramide. CAS No. 54827-14-4. | |
| GM3-Ganglioside labelled by NBD | GM3-Ganglioside labelled by NBD is a specialized GM3-Ganglioside molecule, known for its facile integration with NBD fluorescent probe. Its wide-ranging application encompasses unfathomable diseases, including cancer and neurodegenerative disorders. Synonyms: N-(Acetyl-a-D-neuraminic acid)-(2->3)-O-b-D-galactopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->1)-(2S,3R,4E)-2-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)aminooctanamido-4-octadecene-1,3-diol ammonium salt; aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer linked 7-nitrobenz-2-oxa-1,3-diazole. Molecular formula: C55H90N6O24 H3N. Mole weight: 1236.36. | |
| GM3-Ganglioside labelled by NBD ammonium | GM3-Ganglioside labelled by NBD ammonium is a vital tool in the biomedical industry used for researching and diagnosing various diseases. This product plays a crucial role in studying and understanding the targeting and metabolism of GM3-Ganglioside, a glycosphingolipid involved in neurological disorders and cancer progression. Its NBD ammonium label allows for fluorescence-based detection and visualization in biological systems, enabling accurate analysis and potential therapeutic advancements. Synonyms: (N-Acetyl-a-D-neuraminic acid)-(2->3)-O-b-D-galactopyranosyl-(1->4)-O-b-D-glucopyranosyl-(1->1)-(2S,3R,4E)-2-N-(7-nitrobenz-2-oxa-1,3-diazol-4-yl)aminooctanamido-4-octadecene-1,3-diol ammonium salt; aNeu5Ac(2-3)bDGalp(1-4)bDGlcp(1-1)Cer linked 7-nitrobenz-2-oxa-1,3-diazole ammonium salt. Grade: 95%. Molecular formula: C55H90N6O24.NH3. Mole weight: 1236.36. | |
| GM3NeuGc-Ganglioside | GM3NeuGc-Ganglioside is an indispensable compound, catering to studying cancer. It operates as a remarkable ganglioside variant responsible for pivotal cellular communication and immune system activation. Synonyms: a-Neu5Gc-(2-3)-b-Gal-(1-4)-b-Glc-(1-1)-Cer. | |
| GM4-Ganglioside | GM4-Ganglioside is an essential glycosphingolipid exhibiting tremendous potential as a research for neurodegenerative ailments including Alzheimer's disease and Parkinson's disease. Through its remarkable neuroprotective properties, GM4-Ganglioside safeguard neurons from degeneration. CAS No. 66456-69-7. Molecular formula: C36H68N2O13. Mole weight: 736.9. | |
| GM 6001 - CAS 142880-36-2 | GM 6001, CAS 142880-36-2, is a potent, cell-permeable, broad-spectrum inhibitor of matrix metalloproteinases. Group: Fluorescence/luminescence spectroscopy. | |
| GM 6001, Negative Control - CAS 877381-76-5 | A useful negative control for the MMP inhibitor GM 6001. Group: Fluorescence/luminescence spectroscopy. | |
| GM-90257 | GM-90257 is a microtubule acetylation inhibitor. GM-90257 binds directly to ?-tubulin. GM-90257 prevents the recruitment of ?-tubulin acetyltransferase 1 (?TAT1) to the K40 residue in ?-tubulin. GM-90257 causes Apoptosis, downregulates BCl-2, and activates JNK and PARP. GM-90257 has anticancer activity against breast cancer[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 315703-81-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-155956. |  |
| Gm anionic pept2 | Gm anionic pept2 is isolated from wax moth, Galleria mellonella and it has anti Gram-positive and antifungal activity. Synonyms: Gm anionic peptide 2. | |
| Gm apolipophoricin | Gm apolipophoricin is isolated from wax moth, Galleria mellonella and has anti-Gram-positive bacteria activity. | |
| GMBS | GMBS. Pack Sizes: Milligram Quantities: 100 mg. Order Number: I109. |  www.prochemonline.com |
| GMBS | GMBS is a heterobifunctional cross-linker. GMBS can be used in chemical cross-linking of proteins coupled with mass spectrometry (CXMS) to study protein folding and to map the interfaces between interacting proteins [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 80307-12-6. Pack Sizes: 10 mg; 50 mg; 100 mg. Product ID: HY-W041994. | |
| GMBS | GMBS is a non-cleavable linker widely used in antibody-drug conjugation development. Its unparalleled efficacy stems from its chemical cross-linking ability, promoting the covalent binding of proteins, peptides, antibodies and countless other molecules. Notably, GMBS occupies a key position in the fields of drug delivery systems, diagnostics, and evolving bioconjugation technologies. Synonyms: 4-Maleimidobutyric acid N-succinimidyl ester; N-(gamma-Maleimidobutyryloxy)succinimide; 4-Maleimidobutyric acid N-hydroxysuccinimide ester; 4-Maleimidobutyric acid n-succinimidyl ester; (GMBS); 4-Maleimidobutyric acid NHS. Grade: ≥ 98%. CAS No. 80307-12-6. Molecular formula: C12H12N2O6. Mole weight: 280.23. | |
| GMC 1-116 | GMC 1-116 is a metabolite of clozapine with weak 5-HT2 affinity and high M1 affinity (IC50 = 27 nM). Synonyms: 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-8-ol; 8-Hydroxyclozapine; AC1L9SL1; 6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepin-3-ol. Grade: 99%. CAS No. 63687-94-5. Molecular formula: C18H20N4O. Mole weight: 308.38. | |
| GMC 1-165 | GMC 1-165 is an analogue of clozapine with 5-HT2A/2C and hM1 receptor affinities. Synonyms: 11-(4-Methyl-piperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepin-2-ol; 6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepin-8-ol. Grade: 99%. CAS No. 156632-07-4. Molecular formula: C18H20N4O. Mole weight: 308.38. | |
| GMC 1-169 | GMC 1-169 is an atypical antipsychotic devoid of muscarinic activity. Uses: Atypical antipsychotic. Synonyms: [6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepin-8-yl] trifluoromethanesulfonate. Grade: 99%. CAS No. 183140-97-8. Molecular formula: C19H19F3N4O3S. Mole weight: 440.44. | |
| GMC 15-27 | GMC 15-27 is a selective 5-HT1B/1D antagonist. Synonyms: 4'-(Aminoiminomethyl)-N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-[1,1'-biphenyl]-4-carboxamide. Grade: 98%. CAS No. 256227-71-1. Molecular formula: C27H31N5O2. Mole weight: 457.57. | |
| GMC 2-113 | GMC 2-113 is a selective 5-HT1B antagonist. Synonyms: BDBM50084961; ZINC13805066; N-[4-hydroxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzamide. Grade: 98%. CAS No. 256227-77-7. Molecular formula: C28H29N5O3. Mole weight: 483.56. | |
| GMC 2-118 | GMC 2-118 is a potent and selective 5-HT1B antagonist. Synonyms: [4-[[4-[2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzoyl]amino]-2-(4-methylpiperazin-1-yl)phenyl] methanesulfonate. Grade: 98%. CAS No. 256227-78-8. Molecular formula: C29H31N5O5S. Mole weight: 561.65. | |
| GMC 2-29 | GMC 2-29 is a potent and selective 5-HT1B/1D antagonist. Synonyms: N-[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]-4-[2-methyl-4-(5-methyl-1,3,4-oxadiazol-2-yl)phenyl]benzamide. Grade: 99%. CAS No. 148672-15-5. Molecular formula: C29H31N5O3. Mole weight: 497.59. | |
| GMC 2-83 | GMC 2-83 is an atypical antipsychotic without muscarinic activity. Uses: Atypical antipsychotic. Synonyms: [6-(4-methylpiperazin-1-yl)benzo[b][1,4]benzoxazepin-8-yl] trifluoromethanesulfonate. Grade: 99%. CAS No. 183140-98-9. Molecular formula: C19H18F3N3O4S. Mole weight: 441.42. | |
| GMC 3-15 | GMC 3-15 is a potent and selective 5-HT1B/1D antagonist. Synonyms: 4-[4-[[4-methoxy-3-(4-methylpiperazin-1-yl)phenyl]carbamoyl]phenyl]-3-methylbenzamide. Grade: 99%. CAS No. 691846-63-6. Molecular formula: C27H30N4O3. Mole weight: 458.55. | |
| GMC 61-39 | GMC 61-39 is a clozapine-like atypical antipsychotic. Uses: Atypical antipsychotic. Synonyms: [3-chloro-6-(4-methylpiperazin-1-yl)-5H-benzo[b][1,4]benzodiazepin-8-yl] trifluoromethanesulfonate. Grade: 98%. CAS No. 234113-94-1. Molecular formula: C19H18ClF3N4O3S. Mole weight: 474.88. | |
| GM-CSF from mouse | Animal-component free, recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy. | |
| g-Melanotropin | It has been located in the cryptic region of the ACTH/β-lipotropin precursor protein from the intermediate lobe of bovine pituitary. Synonyms: gamma-Melanocyte-stimulating hormone; Δ-MSH; γ2-MSH; gamma-melanotrophin. CAS No. 72711-43-4. Molecular formula: C74H99N21O16S. Mole weight: 1570.77. | |
| G. mellonella moricin-like peptide A | The moricin-like peptides were particularly active against filamentous fungi, preventing the growth of Fusarium graminearum at 3 microg/ml, and were also active against yeasts, gram-positive bacteria and gram-negative bacteria. | |
| GMF-? human | recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. | |
| GmoDef | GmoDef is isolated from Glossina morsitans [tsetse fly] and has antimicrobial activity. | |
| GMP | Guanosine 5'-monophosphate has been found to be useful in studies of modulation of glutamatergic neurotransmission. Synonyms: Guanosine-5'-monophosphate; 5'-Guanylic Acid. Grade: ≥ 95 % by HPLC. Molecular formula: C10H14N5O8P. Mole weight: 363.22. | |
| GMPαS | GMPαS, a synthesized protein of biotechnological application, is utilized in the biomedical sector for the purpose of investigation into the sprawling domain of inflammatory bowel disease (IBD). This recombinant compound fosters an effective anti-inflammatory response via the suppression of cytokine production associated with the onset of IBD. Additionally, GMPαS's therapeutic possibilities are gaining increasing scientific traction as a potential target for treating a gamut of autoimmune and underlying inflammatory maladies. Synonyms: Guanosine-5'-(α-thio)-monophosphate, Sodium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C10H14N5O7PS (free acid). Mole weight: 379.28 (free acid). | |
| GMP reductase | It converts nucleobase, nucleoside and nucleotide derivatives of G to A nucleotides, and maintains intracellular balance of A and G nucleotides. In melanocytic cells, GMP reductase gene expression may be regulated by MITF. Group: Enzymes. Synonyms: guanosine 5'-monophosphate reductase; NADPH:GMP oxidoreductase (deaminating); guanosine monophosphate reductase; guanylate reductase; NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating); guanosine 5'-phosphate reductase. Enzyme Commission Number: EC 1.7.1.7. CAS No. 9029-32-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1614; GMP reductase; EC 1.7.1.7; 9029-32-7; guanosine 5'-monophosphate reductase; NADPH:GMP oxidoreductase (deaminating); guanosine monophosphate reductase; guanylate reductase; NADPH2:guanosine-5'-phosphate oxidoreductase (deaminating); guanosine 5'-phosphate reductase. Cat No: EXWM-1614. | |
| GMP synthase (glutamine-hydrolysing) | Involved in the de novo biosynthesis of guanosine nucleotides. An N-terminal glutaminase domain binds L-glutamine and generates ammonia, which is transferred by a substrate-protective tunnel to the ATP-pyrophosphatase domain. The enzyme can catalyse the second reaction alone in the presence of ammonia. Group: Enzymes. Synonyms: GMP synthetase (glutamine-hydrolysing); guanylate synthetase (glutamine-hydrolyzing); guanosine monophosphate synthetase (glutamine-hydrolyzing); xanthosine 5'-phosphate amidotransferase; guanosine 5'-monophosphate synthetase. Enzyme Commission Number: EC 6.3.5.2. CAS No. 37318-71-1. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5805; GMP synthase (glutamine-hydrolysing); EC 6.3.5.2; 37318-71-1; GMP synthetase (glutamine-hydrolysing); guanylate synthetase (glutamine-hydrolyzing); guanosine monophosphate synthetase (glutamine-hydrolyzing); xanthosine 5'-phosphate amidotransferase; guanosine 5'-monophosphate synthetase. Cat No: EXWM-5805. | |
| GMQ | GMQ is a ASIC (acid-sensing ion) channel activator with an EC 50 value of 1.83 mM for ASIC3 at pH 7.4. GMQ opens only ASIC3 but no other ASICs at pH 7.4. GMQ can be used for neurological disease research [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5361-15-9. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-107757. | |
| GMQ hydrochloride | GMQ hydrochloride is a selective opener of acid-sensing ion channel 3 (ASIC3) at pH 7.4. It alters the pH dependence of ASIC1a and ASIC1b with no effect on the activation curve of ASIC2a. Synonyms: GMQ monohydrochloride; GMQ HCl; NSC-403387 hydrochloride; NSC 403387 hydrochloride; NSC403387 hydrochloride; NSC-403387 HCl; NSC 403387 HCl; NSC403387 HCl; N-(4-Methyl-2-quinazolinyl)-guanidine hydrochloride; 1-(4-Methylquinazolin-2-yl)guanidine hydrochloride. Grade: ≥98% by HPLC. CAS No. 5361-15-9. Molecular formula: C10H11N5.HCl. Mole weight: 237.69. | |
| GMQ hydrochloride | GMQ hydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 5361-15-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| GMQ hydrochloride | ?95% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GMX1778 | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| GN25 | GN25 is a specific p53-Snail binding inhibitor with antitumor effects[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1227401-27-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117280. | |
| GN44028 | GN44028 is a potent and orally active hypoxia inducible factor (HIF)-1? inhibitor, with an IC50 of 14 nM. GN44028 inhibits hypoxia-induced HIF-1? transcriptional activity without suppressing HIF-1? mRNA expression, HIF-1? protein accumulation, or HIF-1?/HIF-1? heterodimerization. GN44028 can be used in the research of cancers[1][3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1421448-26-1. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110266. | |
| GN 44028 | GN 44028 is a potent HIF-1α inhibitor (IC50 = 14 nM). It suppresses hypoxia-induced HIF-1α transcriptional activity with no effect on HIF-1α mRNA expression, HIF-1α protein accumulation, or HIF-1α/HIF-1β heterodimerization. Synonyms: GN44028; GN 44028; GN-44028; N-(2,3-Dihydro-1,4-benzodioxin-6-yl)-1,4-dihydroindeno[1,2-c]pyrazol-3-amine. Grade: ≥98% by HPLC. CAS No. 1421448-26-1. Molecular formula: C18N15N3O2. Mole weight: 305.33. | |
| GNA002 | GNA002 is a specific, highly potent and covalent EZH2 (enhancer of zeste homolog 2) inhibitor (IC50 = 1.1 μM) that can specifically and covalently bind to Cys668 in the EZH2-SET domain, triggering EZH2 degradation through COOH terminus of Hsp70-interacting protein (CHIP)-mediated ubiquitination. It efficiently reduces EZH2-mediated H3K27 trimethylation and reactivates the tumor suppressor genes silenced by polycomb repressor complex 2 (PRC2). Synonyms: (2Z)-4-[(1S,2S,13S,15R)-7-[(2E)-3,7-Dimethyl-2,6-octadien-1-yl]-6,8-dihydroxy-17,17-dimethyl-5-(3-methyl-2-buten-1-yl)-10,14-dioxo-3,16-dioxapentacyclo[11.4.1.02,11.02,15.04,9]octadeca-4,6,8,11-tetraen-15-yl]-N-(2-ethoxyethyl)-2-methyl-2-butenamide; 2-Butenamide, 4-[(1R,3aS,5S,12aS)-9-[(2E)-3,7-dimethyl-2,6-octadien-1-yl]-3a,4,5,7-tetrahydro-8,10-dihydroxy-3,3-dimethyl-11-(3-methyl-2-buten-1-yl)-7,13-dioxo-1,5-methano-1H,3H-furo[3,4-d]xanthen-1-yl]-N-(2-ethoxyethyl)-2-methyl-, (2Z)-. Grade: ≥98%. CAS No. 1385035-79-9. Molecular formula: C42H55NO8. Mole weight: 701.89. | |
| GNA2 N-Glycan | GNA2 N-Glycan is a resplendent biomedicine used for stduying cancer, inflammatory disorders, and neurodegenerative conditions. Synonyms: Monogalacto, fucosylated, biantennary N-linked glycan. | |
| Gnaphaline | A derivative of Flavoxate. Flavoxate is an anticholinergic with antimuscarinic effects. Synonyms: 4H-1-Benzopyran-4-one,5,7-dihydroxy-3,8-dimethoxy-2-phenyl-; 5,7-Dihydroxy-3,8-Dimethoxyflavon. Grade: > 95%. CAS No. 33803-42-8. Molecular formula: C17H14O6. Mole weight: 314.30. | |
| GNCP-2 | GNCP-2 is an antimicrobial cationic peptide found in Guinea pig neutrophils. It has antimicrobial activity. | |
| GNE-0439 | GNE-0439 is an ion channel selective blocker with effect of relieving pain. Synonyms: (4-(4-Propylcyclohexyl)benzoyl)-L-valine; GNE 0439. CAS No. 1241902-40-8. Molecular formula: C21H31NO3. Mole weight: 345.48. | |
| GNE-049 | GNE-049 is a selective and highly potent inhibitor of CBP with an IC50 of 1.1 nM in TR-FRET assay. It also inhibits BRET and BRD4 with IC50s of 12 and 4200 nM, respectively. Synonyms: 1-{3-[7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl]-1-(oxan-4-yl)-1,4,6,7-tetrahydro-5H-pyrazolo[4,3-c]pyridin-5-yl}ethan-1-one; 1-{3-[7-(difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-1,2,3,4-tetrahydroquinolin-1-yl]-1-(oxan-4-yl)-1H,4H,5H,6H,7H-pyrazolo[4,3-c]pyridin-5-yl}ethan-1-one; Ethanone, 1-[3-[7-(difluoromethyl)-3,4-dihydro-6-(1-methyl-1H-pyrazol-4-yl)-1(2H)-quinolinyl]-1,4,6,7-tetrahydro-1-(tetrahydro-2H-pyran-4-yl)-5H-pyrazolo[4,3-c]pyridin-5-yl]-. Grade: ≥98%. CAS No. 1936421-41-8. Molecular formula: C27H32F2N6O2. Mole weight: 510.58. | |
| GNE-049 | GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1936421-41-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-108435. | |
| GNE-064 | GNE-064 (compound 5) is a selective, orally active and highly soluble inhibitor of SMARCA4, SMARCA2 and PBRM1 bromodomains 5. GNE-064 inhibits SMARCA4 with an IC50 of 0.035 ?M and inhibits SMARCA2 with an EC50 of 0.10 ?M. GNE-064 possess Kds with 0.01, 0.016, 0.018 and 0.049 ?M for SMARCA4, SMARCA2, PBRM1 bromodomains 5 and PBRM1 bromodomains 2, repectively. GNE-064 can be used as a chemical probe for the research of agent synthesis[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1997321-20-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149026. | |
| GNE0877 | GNE0877 is a highly selective, orally active and brain-penetrant LRRK2 inhibitor with an IC50 of 3 nM and a Ki of 0.7 nM. GNE0877 can be used for the research of neuroscience[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1374828-69-9. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15796. | |
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