A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Gp100 (17-25) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: H-Ala-Leu-Leu-Ala-Val-Gly-Ala-Thr-Lys-OH; Melanocyte Protein PMEL 17 (17-25). Grade: >95%. CAS No. 184297-65-2. Molecular formula: C38H70N10O11. Mole weight: 843.02.
gp100 (174-190)
Gp100 (174-190) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (174-190).
gp100 (175-189)
Gp100 (175-189) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (175-189).
gp100 (177(8)-186)
Gp100 (177(8)-186) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (177(8)-186).
gp100 (182-191)
Gp100 (182-191) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (182-191).
Gp100 (25-33) (human)
Gp100 (25-33) is an amino acid fragment of human melanoma antigen. Grade: >98%. CAS No. 212370-40-6. Molecular formula: C52H82N16O14. Mole weight: 1155.31.
Gp100 (25-33), human
Gp100 (25-33), human (Hgp100 (25-33)) is the amino acids 25-33 fragment of the human melanoma antigen. Gp100 (25-33), human is a 9-amino acid (AA) epitope restricted by MHC class I H-2Db and recognized by the T cells. Gp100 (25-33), human has immunogenicity and induces specific T cells. Gp100 (25-33), human can be used for the cancer research, such as melanoma[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hgp100 (25-33). CAS No. 212370-40-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1585.
Gp100 (25-33), mouse
Gp100 (25-33) is a tumor antigen glycoprotein fragment. CAS No. 212370-36-0. Molecular formula: C46H69N15O17. Mole weight: 1104.13.
Gp100 (25-33), mouse
Gp100 (25-33), mouse sequence is found in residues 25 to 33 of the mouse self/tumor antigen glycoprotein (mgp100). Mgp100 is an enzyme involved in pigment synthesis, and the epitope fragment is expressed in both normal melanocytes and melanoma cells[1]. Uses: Scientific research. Category: Peptides. Alternative Names: Mgp100 (25-33). CAS No. 212370-36-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2506.
gp100 (420-437)
Gp100 (420-437) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (420-437).
gp100 (457-466)
Gp100 (457-466) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (457-466).
gp100 (471-480)
Gp100 (471-480) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (471-480).
gp100 (476-485)
Gp100 (476-485) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (476-485). Mole weight: 1190.4000000000001.
gp100 (529-537)
Gp100 (529-537) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (529-537).
gp100 (570-579)
Gp100 (570-579) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (570-579).
gp100 (614-622)
Gp100 (614-622) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (614-622).
gp100 (619-627)
Gp100 (619-627) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (619-627).
Gp100 619-627
Gp100 619-627 is the 619-627 amino acid fragment of human melanoma antigen glycoprotein 100 (GP100). GP100 has been widely studied as a target for melanoma immunotherapy. Synonyms: L-Valine, L-arginyl-L-leucyl-L-methionyl-L-lysyl-L-glutaminyl-L-α-aspartyl-L-phenylalanyl-L-seryl-; Arg-Leu-Met-Lys-Gln-Asp-Phe-Ser-Val. Grade: ≥95%. CAS No. 187987-68-4. Molecular formula: C49H82N14O14S. Mole weight: 1123.33.
gp100 (630-638)
Gp100 (630-638) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (630-638).
gp100 (639-647)
Gp100 (639-647) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (639-647).
gp100 (71-78)
Gp100 (71-78) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (71-78).
gp100 (86-95)
Gp100 (86-95) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (86-95).
gp100 (87-95)
Gp100 (87-95) is a peptide derived from Melanocyte Protein PMEL 17, a 100 kDa type I transmembrane glycoprotein that is expressed primarily in pigment cells of the skin and eye. Synonyms: Melanocyte Protein PMEL 17 (87-95).
GP130 modulator-1
GP130 modulator-1 (compound A33) is a gp130 signaling pathway modulator. GP130 modulator-1 can be used in the study of inflammatory and degenerative disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2375779-31-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159742.
GP1a
GP1a is a potent agonist of cannabinoid receptor 2 (CB2). Gp1a is beneficial to skin wound healing. GP1a inhibits inflammation and fibrogenesis while promoting re-epithelialization[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 511532-96-0. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-110050.
GP 1a
GP 1a is a highly selective CB2 receptor inverse agonist (pEC50 = 7.1), which displays approximately 30-fold selectivity for CB2 receptors over CB1 receptors. Synonyms: N-(Piperidin-1-yl)-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide; 1-(2,4-dichlorophenyl)-6-methyl-N-(1-piperidinyl)-4H-indeno[1,2-c]pyrazole-3-carboxamide. Grade: ≥99% by HPLC. CAS No. 511532-96-0. Molecular formula: C23H22Cl2N4O. Mole weight: 441.35.
GP 2a
GP 2a is a selective CB2 receptor agonist that also dispalys modest agonism at CB1 receptors with Ki values of 7.6 and 900 nM, respectively. Synonyms: N-Cyclohexyl-1-(2,4-dichlorophenyl)-1,4-dihydro-6-methylindeno[1,2-c]pyrazole-3-carboxamide. Grade: ≥99% by HPLC. CAS No. 919077-81-9. Molecular formula: C24H23Cl2N3O. Mole weight: 440.36.
GP2G
GP2G is an extraordinary pharmaceutical, finding applications in studying numerous autoimmune afflictions encompassing rheumatoid arthritand multiple sclerosis. Its mechanism of action entails robust immunosuppression alongside notable anti-inflammatory properties. Synonyms: P1-(5'-Guanosyl)-P2-(5'-guanosyl)-diphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. Molecular formula: C20H26N10O15P2(free acid). Mole weight: 708.43 (free acid).
GP (33-41)
GP(33-41), a 9-aa-long peptide, is the optimal sequence of the GP1 epitope of lymphocytic choriomeningitis virus. Synonyms: H-Lys-Ala-Val-Tyr-Asn-Phe-Ala-Thr-Cys-OH; L-lysyl-L-alanyl-L-valyl-L-tyrosyl-L-asparaginyl-L-phenylalanyl-L-alanyl-L-threonyl-L-cysteine. Grade: ≥95%. CAS No. 161928-86-5. Molecular formula: C46H69N11O13S. Mole weight: 1016.18.
GP3G
GP3G is a kind of diguanosine polyphosphate, could be found in human plasma. Synonyms: G(5')ppp(5')G; P1-(Guanosyl) P3-(5'-(guanosyl))triphosphate. Grade: ≥ 95 % by HPLC. Molecular formula: C20H27N10O18P3. Mole weight: 788.41.
GP3G (Unmethylated Cap Analog)
GP3G is a kind of diguanosine polyphosphate, could be found in human plasma. Synonyms: GpppG; G(5')ppp(5')G Cap Analog; Diguanosine triphosphate; Diguanosine-5'-triphosphate; P1-(Guanosyl) P3-(5'-(guanosyl))triphosphate; CAP; Guanosine 5'-(tetrahydrogen triphosphate), P''→5'-ester with guanosine; Guanosine 5'-(tetrahydrogen triphosphate), 5'→5'-ester with guanosine; Guanosine triphosphate, 5'→5'-ester with guanosine; Guanosine, 5'-ester with guanosine 5'-(tetrahydrogen triphosphate); Diguanosine 5',5'''-triphosphate; Gp3G; P1,P3-Diguanosine 5'-triphosphate; Guanosine-5'-triphosphate-5'-Guanosine. Grade: ≥95% by HPLC. CAS No. 6674-45-9. Molecular formula: C20H27N10O18P3. Mole weight: 788.41.
GP4G
GP4G, a naturally occurring compound found in green tea and seaweed, is a multifunctional ingredient commonly employed as a dietary supplement and cosmetic product ingredient. Various investigations indicate its significant role in augmenting skin cell metabolism and safeguarding against ultraviolet radiation-induced harm. Moreover, studies exhibit the potential of GP4G in bolstering brain function and exercise performance. The compound is also a promising candidate in treating afflictions such as Alzheimer's disease and stroke. Synonyms: P1-(5'-Guanosyl)-P4-(5'-guanosyl)-tetraphosphate. Grade: ≥ 95 % by HPLC. Molecular formula: C20H28N10O21P4. Mole weight: 868.39.
GP4G
GP4G (Diguanosine tetraphosphate) is a symmetrical bis-diphospho nucleoside that can be isolated from the cysts of Artemia salina. GP4G is an epithelial cell and hair growth regulator[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Diguanosine tetraphosphate. CAS No. 4130-19-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137680.
Gp4U
Gp4U is an innovative and groundbreaking biomedical compound, used for studying diverse malignancies such as breast, lung and colon cancer. Synonyms: P1- (5'- Guanosyl)- P4- (5'- uridyl)- tetraphosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 79695-25-3. Molecular formula: C19H27N7O22P4 (free acid). Mole weight: 829.4 (free acid).
GP531
GP531 is a novel riboside with similar structural and anti-ischemic properties to the adenosine-regulating agent (ARA) acadesine. Synonyms: 5-amino-1-[(2R,3R,4S,5R)-5-[(benzylamino)methyl]-3,4-dihydroxyoxolan-2-yl]imidazole-4-carboxamide; 5-amino-1-beta-D-(5'-benzylamino-5'-deoxyribofuranosyl)imidazole-4-carboxamide; GP 531; GP-531; GP531. CAS No. 142344-87-4. Molecular formula: C16H21N5O4. Mole weight: 347.37.
gp91 ds-tat
gp91 ds-tat, a biological active peptide, is a NADPH oxidase 2 (Nox2) inhibitor. gp91 ds-tat blocks NADPH oxidase-dependent superoxide production. gp91 ds-tat ameliorates high glucose-induced increase in total ROS, LPOs and iron levels. gp91 ds-tat inhibits homocysteine (Hcy)-induced activation of NLRP3 inflammasomes and restores Hcy-inhibited lysosomal TRPML1 channel activity. gp91 ds-tat improves cerebrovascular and cognitive function in APP/PS1 mice. gp91 ds-tat can be used for the study of Alzheimers disease (AD), glomerular inflammation and cardiovascular disease[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 329902-61-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P5381.
gp91 ds-tat
gp91 ds-tat is composed of gp91phox sequence linked to the human immunodeficiency virus-tat peptide. It acts as a NADPH oxidase inhibitor. Synonyms: H-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Cys-Ser-Thr-Arg-Ile-Arg-Arg-Gln-Leu-NH2. CAS No. 329902-61-6. Molecular formula: C98H190N50O22S. Mole weight: 2452.94.
GpAp is a synthetic linear dinucleotide not binding to the c-diGMP-I riboswitch. Synonyms: Guanylyl- (3' -≥ 5')- adenosine- 3'- O- phosphate, sodium salt. Grade: ≥ 95% by HPLC. CAS No. 17332-08-0. Molecular formula: C20H26N10O14P2. Mole weight: 692.4.
GPAT-IN-1
GPAT-IN-1 is a glycerol-3-phosphate acyltransferase (GPAT) inhibitor with an IC50 value of 8.9 μM. GPAT-IN-1 can be used for the research of obesity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1204347-51-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-153628.
GPBAR1-IN-3
GPBAR1-IN-3, a CysLT1R antagonist, is a selective GPBAR1 agonist with an EC50 of 0.17 μM. Synonyms: (S)-2-((3-(2-methylbutoxy)phenoxy)methyl)quinoline. Molecular formula: C21H23NO2. Mole weight: 321.41.
GPBAR-A
GPBAR-A is a GPBA receptor agonist. GPBAR-A increases GLP-1 secretion from intestinal cultures. Synonyms: GPBAR-A; GPBAR A; GPBARA; 4-[[3,5-Bis(trifluoromethyl)phenyl]methyl]-6-(2-fluorophenyl)-4,5-dihydro-pyrido[3,2-f]-1,4-oxazepin-3(2H)-one. Grade: ≥98% by HPLC. CAS No. 877052-79-4. Molecular formula: C23H15F7N2O2. Mole weight: 484.37.
GPBAR-A
GPBAR-A. Group: Biochemicals. Grades: Purified. CAS No. 877052-79-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GpCp
GpCp is an analogue of GDP and has been found to be hydrolytically stable. Synonyms: GMPCP; Guanosine-5'-[(α,β)-methyleno]diphosphate, Sodium salt. Grade: ≥ 95 % by HPLC. CAS No. 32381-15-0. Molecular formula: C11H14N5Na3O10P2. Mole weight: 507.20.
GpCpp
GpCpp is an analogue of GTP and could be used as a stabilizer in some microtubule cryoelectron microscopy studies. Uses: Antiviral agents. Synonyms: GMPCPP; Guanosine-5'-[(α,β)-methyleno]triphosphate. Grade: ≥ 95 % by HPLC. CAS No. 14997-54-7. Molecular formula: C11H18N5O13P3. Mole weight: 521.21.
GPCR Compound Library
A unique collection of 1633 GPCR-active agents for high throughput screening and high content screening for GPCR drug discovery, and new GPCR target identification and research; - Potential to find new GPCR drug candidates by screening against orphan GPCRs; - Bioactivity and safety confirmed by pre-clinical research and clinical trials, and some of them are approved by FDA; - Targets include 5-HT receptor, dopamine receptor, opioid receptor, adrenergic receptor, mGluR, Cannabinoid receptor, ETA-receptor, etc; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L1500. Categories: GPCR Compounds Libraries.
GPCR Compound Library Plus
Quantity: well-chosen 338 GPCR targeting compounds with unique structures; - High bioactivity: All compounds with IC50 below 3. 5 μM; - Targets include 21 various GPCR subtypes; - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - HNMR/LCMS validated to ensure high purity and quality; - A powerful tool for GPCR drug development and target identification. Uses: Scientific use. Product Category: L1580. Categories: GPCR Compounds Libraries Plus.
G-PET PETG 3D Printing Filament
G-PET PETG 3D Printing Filament.
GPhos Pd G6
GPhos Pd G6 (GPhos Pd G6 TES) is a palladium catalyst. GPhos Pd G6 catalyzes the Buchwald-Hartwig amination reaction and promotes C-N bond formation between aryl chlorides and amines. GPhos Pd G6 is a pharmaceutical intermediate used for the synthesis of various active compounds[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GPhos Pd G6 TES. CAS No. 2489525-81-5. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g; 5 g. Product ID: HY-W590989.
GPI-15427
GPI-15427 is a potent PARP-1 inhibitor capable of crossing the blood-brain barrier, which can significantly increased the antitumor activity of the methylating agent TMZ against malignant melanoma, glioblastoma multiforme, or lymphoma growing at the CNS site. GPI-15427 acts as a potent inhibitor of the enzyme, being capable of inhibiting the activity of purified PARP-1 at nanomolar concentrations. GPI-15427 induced significant sensitization to radiotherapy, representing a promising new treatment in the management of HNSCC. Uses: Poly(adp-ribose) polymerase inhibitors. Synonyms: GPI 15427; GPI15427; 10-((4-Methylpiperazin-1-yl)methyl)chromeno(4,3,2-de)phthalazin-3(2H)-one. CAS No. 805242-85-7. Molecular formula: C20H20N4O2. Mole weight: 348.41.
GPi 688
GPi 688 is an allosteric glycogen phosphorylase inhibitor that inhibits glucagon-mediated hyperglycemia in the rat. Synonyms: GPi 688; GPi688; GPi-688; 2-Chloro-N-[1-[(2R)-2,3-dihydroxypropyl]-1,2,3,4-tetrahydro-2-oxo-3-quinolinyl]-6H-thieno[2,3-b]pyrrole-5-carboxamide. Grade: ≥99% by HPLC. CAS No. 918902-32-6. Molecular formula: C19H18ClN3O4S. Mole weight: 419.88.
GPLGIAGQ
GPLGIAGQ, is an MMP2-cleaved polypeptide that is used as a stimulus-sensitive connector in both liposomes and micelle nanoceroses for targeted therapy of tumors triggered by MMP2. Synonyms: L-Glutamine, glycyl-L-prolyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-; Gly-Pro-Leu-Gly-Ile-Ala-Gly-Gln. Grade: ≥97% by HPLC. CAS No. 109053-09-0. Molecular formula: C31H53N9O10. Mole weight: 711.81.
GPNA hydrochloride
GPNA hydrochloride is a well known substrate of the enzyme γ-glutamyltransferase (GGT). GPNA hydrochloride is a specific glutamine (Gln) transporter ASCT2 inhibitor. GPNA hydrochloride also inhibit Na+-dependent carriers, such as SNAT family (SNAT1/2/4/5), and the Na+-independent leucine transporters LAT1/2. GPNA reversibly induces apoptosis in A549 cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 67953-08-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W011391.
GPP 78
GPP 78 is a potent inhibitor of Nicotinamide phosphoribosyltransferase (Nampt) with an IC50 value of 3 nM. Synonyms: CAY10618; NMPRTase Inhibitor; N-[1,1'-biphenyl]-2-yl-4-(3-pyridinyl)-1H-1,2,3-triazole-1-octanamide. Grade: ≥95%. CAS No. 1202580-59-3. Molecular formula: C27H29N5O. Mole weight: 439.6.
GPP 78 hydrochloride
GPP 78 hydrochloride is an inhibitor of nicotinamide phosphoribosyltransferase (NAMPT), which is subsequently converted to NAD+. It was shown to induce autophagy in neuroblastoma cells. Synonyms: GPP 78 hydrochloride; GPP78 hydrochloride; GPP-78 hydrochloride; N-[1,1'-Biphenyl]-2-yl-4-(3-pyridinyl)-1H,1,2,3-triazole-1-octanamide hydrochloride. Grade: ≥98% by HPLC. Molecular formula: C27H29N5O.HCl. Mole weight: 476.01.
GPP 78 hydrochloride
GPP 78 hydrochloride. Group: Biochemicals. Grades: Purified. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GppNH2
GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPN; Guanosine-5'-(β-amino)-diphosphate. Grade: ≥ 95 % by HPLC. Molecular formula: C10H16N6O10P2. Mole weight: 442.21.
GppNHp - Tetralithium salt
The tetrasodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Tetralithium salt; GMPPNHP. Grade: ≥ 95 % by HPLC. CAS No. 64564-03-0. Molecular formula: C10H13N6ONa413P3. Mole weight: 611.13.
GppNHp - Trisodium salt
The trisodium salt form of GppNH2, one of the analogue of GTP, has been found to be probably useful in studies of modulating cell signals related to G proteins. Synonyms: GMPPNP; Guanosine-5'-[( β,γ )-imido]triphosphate, Trisodium salt; GMPPNHP. Grade: ≥ 90 % by HPLC. CAS No. 148892-91-5. Molecular formula: C10H14N6Na3O13P3. Mole weight: 588.14.
GPR120 Agonist 1
GPR120 Agonist 1 is a potent and selective GPR120 agonist with promising antidiabetic effects and good safety. Synonyms: GPR120 agonist 4x; 3-(4-((3-(4-chloro-2-fluorophenyl)-5-(trifluoromethyl)isothiazol-4-yl)methoxy)-3,5-difluorophenyl)propanoic acid; Benzenepropanoic acid, 4-[[3-(4-chloro-2-fluorophenyl)-5-(trifluoromethyl)-4-isothiazolyl]methoxy]-3,5-difluoro-. Grade: ≥95%. CAS No. 1628448-77-0. Molecular formula: C20H12ClF6NO3S. Mole weight: 495.82.
GPR120 Agonist 3
GPR120 Agonist 3 is a selective Gpr120 agonist with a logEC50 of 7.62. Uses: Scientific research. Category: Signaling pathways. CAS No. 1599477-75-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101492.
GPR120-IN-1
GPR120-IN-1, a cell-permeable azaspiroundecanyl acetic acid compound, is an orally available, selective agonist of GPR120 (EC50 = ~0.35 μM) that demonstrates potent selectivity over another lipid-sensing G-protein, GPR40 (FFAR1). Synonyms: 2-[3-[2-chloro-5-(trifluoromethoxy)phenyl]-3-azaspiro[5.5]undecan-9-yl]acetic acid; GPR120 Compound A; MDK77754; MDK-77754; MDK 77754; GPR120 cpdA. CAS No. 1599477-75-4. Molecular formula: C19H23ClF3NO3. Mole weight: 405.84.
GPR120 modulator 1
GPR120 modulator 1 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 1; 1050506-75-6; 2-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenoxy]acetic acidAcetic acid, 2-[4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methylphenoxy]-GPR120-modulator-1. Grade: >98%. CAS No. 1050506-75-6. Molecular formula: C19H16ClNO4S. Mole weight: 389.85.
GPR120 modulator 2
GPR120 modulator 2 is useful for modulating G protein-coupled receptor 120 (GPR120). Synonyms: GPR120 modulator 2; 1050506-87-0; 3-[4-[[4-(2-chlorophenyl)-1,3-thiazol-2-yl]methoxy]-2-methylphenyl]propanoic acidBenzenepropanoic acid, 4-[[4-(2-chlorophenyl)-2-thiazolyl]methoxy]-2-methyl-3-(4-{[4-(2-CHLOROPHENYL)-1,3-THIAZOL-2-YL]METHOXY}-2-METHYLPHENYL)PROPANOIC ACID. Grade: >98%. CAS No. 1050506-87-0. Molecular formula: C20H18ClNO3S. Mole weight: 387.88.
GPR132 antagonist 1
GPR132 antagonist 1 is a GPR132 antagonist with EC50 value of 0.075 μM. Synonyms: NOX-6-18. CAS No. 898211-21-7. Molecular formula: C18H17NO5S. Mole weight: 359.40.
GPR132 antagonist 1
GPR132 antagonist 1 (GPR132-B-160, Compound 25) is a GPR132 antagonist with an EC50 value of 0.075 μM. GPR132 antagonist 1 has promote insulin secretion activity with an EC50 value of 0.7 μM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 898211-21-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-157189.
GPR139 agonist-2
GPR139 agonist-2 (compound 20a) is a potent GPR139 agonist with an EC50 of 24.7 nM. GPR139 agonist-2 rescues the social interaction deficits and alleviates cognitive deficits in murine schizophrenia models. GPR139 agonist-2 has the potential for antischizophrenia drug research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2983118-29-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-149651.
GPR139 agonist-2
GPR139 agonist-2 is a potent GPR139 agonist with an EC50 of 24.7 nM. GPR139 agonist-2 has the potential for antischizophrenia drug research. Synonyms: (S)-2-(4-Oxopyrrolo[1,2-d][1,2,4]triazin-3(4H)-yl)-N-(1-(4-(trifluoromethoxy)phenyl)ethyl)acetamide. CAS No. 2983118-29-0. Molecular formula: C17H15F3N4O3. Mole weight: 380.32.
GPR15 antagonist-1
GPR15 antagonist-1 (Compound 5) is a GPR15 antagonist. G protein-coupled receptor 15 (GPR15) is an extensively studied GPCRs involving HIV infection, colonic inflammation, and smoking-related diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 252280-67-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-177116.
GPR183 antagonist-3
GPR183 antagonist-3 (compound 33) is an oral active GPR183 antagonist with the IC50 of 8.7 μM. GPR183 antagonist-3 displays strong in vitro antimigration and anti-inflammatory activity in monocytes, and improves the pathological symptoms of DSS-induced experimental colitis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3054870-33-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-157939.