A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
GPR84 antagonist 1 is a high affinity and highly selective human GPR84 competitive antagonist. Molecular formula: C26H22N4O2. Mole weight: 422.48.
GPR84 antagonist 2
GPR84 antagonist 2 is a potent, selective and orally active GPR84 antagonist (IC50 = 8.95 nM), which has the potential for the study of ulcerative colitis. It shows improved potency in the calcium mobilization assay and inhibits the chemotaxis of neutrophils and macrophages upon GPR84 activation. Synonyms: Dibenzo[b,f]thiepin-10-ol, 1-chloro-, 10,10'-(hydrogen phosphate), sodium salt (1:1). CAS No. 2244269-74-5. Molecular formula: C28H16Cl2NaO4PS2. Mole weight: 605.42.
GPR84 antagonist 8
GPR84 antagonist 8 is a selective antagonist of GPR84. Synonyms: 4H-Pyrimido[6,1-a]isoquinolin-4-one, 2-(1,4-dioxan-2-ylmethoxy)-6,7-dihydro-9-(2-pyridinylmethoxy)-; 2-(1,4-Dioxan-2-ylmethoxy)-9-(2-pyridinylmethoxy)-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one. Grade: ≥95%. CAS No. 1445846-30-9. Molecular formula: C23H23N3O5. Mole weight: 421.45.
gpr endopeptidase
Initiates the degradation of small, acid-soluble proteins during spore germination in Bacillus megaterium. Type example of peptidase family M63. Group: Enzymes. Synonyms: germination proteinase. Enzyme Commission Number: EC 3.4.24.78. CAS No. 75718-32-0. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4362; gpr endopeptidase; EC 3.4.24.78; 75718-32-0; germination proteinase. Cat No: EXWM-4362.
G-Protein antagonist peptide is a competitive and reversible inhibitor of M2 muscarinic cholinergic receptors. G-Protein antagonist peptide inhibits M2 muscarinic receptor activation of Gi or Go and suppresses Gs activation by β-adrenoceptors. Synonyms: GPAnt-2; G Protein Antagonist. Grade: >98%. CAS No. 143675-79-0. Molecular formula: C57H64N12O9S. Mole weight: 1093.27.
G-Protein antagonist peptide acetate
G-Protein antagonist peptide is a competitive and reversible inhibitor of M2 muscarinic cholinergic receptors. G-Protein antagonist peptide inhibits M2 muscarinic receptor activation of Gi or Go and suppresses Gs activation by β-adrenoceptors. Synonyms: GPAnt-2 acetate; G Protein Antagonist acetate. Molecular formula: C59H68N12O11S. Mole weight: 1153.33.
G-protein coupled receptor 143 (126-134)
G-protein coupled receptor 143 (126-134) is a 9-aa peptide. G-protein coupled receptor 143 is a receptor for tyrosine, L-DOPA and dopamine. Its activity is mediated by G proteins which activate the phosphoinositide signaling pathway. Synonyms: Ocular albinism type 1 protein (126-134).
G-protein-coupled receptor kinase
Requires G-protein for activation and therefore belongs to the family of G-protein-dependent receptor kinases (GRKs). All members of this enzyme subfamily possess a highly conserved binding site for 1-phosphatidylinositol 4,5-bisphosphate. (cf. EC 2.7.11.14, rhodopsin kinase and EC 2.7.11.15, β-adrenergic-receptor kinase). Group: Enzymes. Synonyms: G protein-coupled receptor kinase; GPCR kinase; GPCRK; GRK4; GRK5; GRK6; STK16. Enzyme Commission Number: EC 2.7.11.16. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3135; G-protein-coupled receptor kinase; EC 2.7.11.16; G protein-coupled receptor kinase; GPCR kinase; GPCRK; GRK4; GRK5; GRK6; STK16. Cat No: EXWM-3135.
GPRP
GPRP is an inhibitor of fibrin polymerization. It binds to fibrinogen (Ki = 400 mM). Synonyms: Gly-pro-arg-pro; L-Proline,glycyl-L-prolyl-L-arginyl-; (S)-1-((S)-2-((S)-1-(2-aminoacetyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxylic acid. CAS No. 67869-62-9. Molecular formula: C18H31N7O5. Mole weight: 425.48.
GPRP
GPRP (Pefa 6003) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2]. Uses: Scientific research. Group: Peptides. Alternative Names: Gly-Pro-Arg-Pro; Pefa 6003. CAS No. 67869-62-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0074.
GPRP acetate
GPRP acetate, a fibrinogen-related peptide, inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa). Synonyms: Pefa 6003; Pefabloc FG; GPRP.CH3CO2H; glycyl-L-prolyl-L-arginyl-L-proline acetic acid; (S)-1-((S)-2-((S)-1-(2-aminoacetyl)pyrrolidine-2-carboxamido)-5-guanidinopentanoyl)pyrrolidine-2-carboxylic acid acetate; H-Gly-Pro-Arg-Pro-OH acetate. Grade: ≥95%. CAS No. 157009-81-9. Molecular formula: C18H31N7O5.C2H4O2. Mole weight: 485.53.
GPRP acetate
GPRP acetate (Gly-Pro-Arg-Pro acetate) is a fibrin polymerization inhibitor that inhibits the interaction of fibrinogen with the platelet membrane glycoprotein IIb/IIIa complex (GPIIb/IIIa)[1][2][3]. Uses: Scientific research. Group: Peptides. Alternative Names: Gly-Pro-Arg-Pro acetate; Pefa 6003 acetate. CAS No. 157009-81-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-P0074A.
GPS491
GPS491 (EC50 = 0.47 μM) inhibits the expression of HIV-1 structural protein Gag, changes the accumulation of HIV-1 RNA, reduces the abundance of RNAs encoding the structural proteins, and increases the level of viral RNAs encoding the regulatory proteins. Synonyms: 2-(trifluoromethyl)-N-(6-(trifluoromethyl)benzo[d]thiazol-2-yl)thiazole-5-carboxamide. Grade: ≥98%. CAS No. 2655502-29-5. Molecular formula: C13H5F6N3OS2. Mole weight: 397.32.
GPX-100 is an analogue of the anthracycline antineoplastic antibiotic doxorubicin. GPX-100 intercalates DNA and interacts with topoisomerase II, thereby inhibiting DNA replication and repair and RNA and protein synthesis. GPX-100 was designed to be a non-cardiotoxic anthracycline antibiotic. Synonyms: Epirubicin Impurity 1; 13-Deoxyepirubicin; GPX 100; GPX-100; 13-deoxy-doxorubicin; (1S,3R)-3,5,12-Trihydroxy-3-(2-hydroxyethyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydro-1-tetracenyl 3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranoside; 5,12-Naphthacenedione, 10-[(3-amino-2,3,6-trideoxy-α-L-arabino-hexopyranosyl)oxy]-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyethyl)-1-methoxy-, (8R,10S)-. Grade: ≥95%. CAS No. 952648-77-0. Molecular formula: C27H31NO10. Mole weight: 529.54.
GPX150
GPX-150 is a synthetic non-cardiotoxic analogue of the anthracycline antibiotic doxorubicin with potential antineoplastic activity. Anthracycline analogue GPX-150 intercalates DNA and impedes the activity of topoisomerase II, inducing single and double-stranded breaks in DNA; inhibiting DNA replication and/or repair, transcription, and protein synthesis; and activating tumor cell apoptosis. Synonyms: GPX 150; GPX-150; 5(8H)-Naphthacenone, 10-((3-amino-2,3,6-trideoxy-alpha-L-arabino-hexopyranosyl)oxy)-7,9,10,12-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyethyl)-12-imino-1-methoxy-, (8R,10S)-. CAS No. 236095-29-7. Molecular formula: C27H32N2O9. Mole weight: 528.56.
GPX1 human
recombinant, expressed in E. coli, His tagged, >90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy.
GPX4-IN-3
GPX4-IN-3 is an effective inhibitor of glutathione peroxidase 4 (GPX4) and can be used as a selective ferroptosis inducer. It shows 71.7% inhibition for GPX4 with 1 μM. Synonyms: NSC-835419; 2-(benzo[b]thiophen-3-yl)-2-(2-chloro-N-(4-(oxazol-5-yl)phenyl)acetamido)-N-phenethylacetamide. Grade: ≥95%. Molecular formula: C29H24ClN3O3S. Mole weight: 530.04.
GPX4-IN-3
GPX4-IN-3 (26a) is a potent glutathione peroxidase 4 (GPX4) inhibitor as a selective ferroptosis inducer. GPX4-IN-3 (26a) exhibits 71.7% inhibition for GPX4 with 1 ?M[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2761004-85-5. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-141809.
GPX4-IN-4
GPX4-IN-4 (Compound 24) is a potent GPX4 inhibitor. GPX4-IN-4 can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2920221-53-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149923.
GPX4-IN-5
GPX4-IN-5 is a covalent inhibitor of GPX4 (IC50: 0.12 ?M). GPX4-IN-5 can induce ferroptosis and has anti-tumor effects. GPX4-IN-5 can be used in the study of triple-negative breast cancer (TNBC)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2922824-09-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-155663.
GQ-16
GQ-16 is an effective and partial agonist for peroxisome proliferator-activated receptor γ (PPARγ) (Ki = 160 nM). It does not activate PPARα, PPARβ/δ, or RXRα. Synonyms: 5Z-[(5-bromo-2-methoxyphenyl)methylene]-3-[(4-methylphenyl)methyl]-2,4-thiazolidinedione. Grade: ≥98%. CAS No. 870554-67-9. Molecular formula: C19H16BrNO3S. Mole weight: 418.3.
GQ-16
GQ-16 is a moderate affinity ligand for the ligand-binding domain (LBD) of PPARγ , exhibiting a K i of 160 nM. GQ-16 is an effective inhibitor of Cdk5-mediated phosphorylation of PPAR&gamma. GQ-16 is a partial agonist of PPARγ with reduced adipogenic actions. GQ-16 promotes insulin Sensitization without weight gain [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 870554-67-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-111254.
GQ1b-Ganglioside
GQ1b-Ganglioside is a vital biomedical product utilized for its neuroprotective properties. This compound acts as a crucial element in the treatment of various neurological disorders, including Guillain-Barré syndrome and Miller Fisher syndrome. Synonyms: Tetrasialoganglioside 1b; Ganglioside GQ1b; GQ1b. CAS No. 68652-37-9.
GQ3-Oligosaccharide
GQ3-Oligosaccharide is an extraordinary bioactive compound employed in the research of neurodegenerative ailments, showcasing remarkable neuroprotective attributes. GQ3-Oligosaccharide actively contributes to the diminution of oxidative stress and inflammation, thereby facilitating the augmentation of neuronal viability and efficacious functioning. Synonyms: Neu5Aca2-8Neu5Aca2-8Neu5Acb2-8Neu5Aca2-3Galb1-4Glc. Molecular formula: C56H86N4O43Na4. Mole weight: 1595.24.
GR103545
GR103545 is a potent and selective agonist of the κ-opioid receptor (κ-OR). Synonyms: GR-103545 fumarate; (R)-Methyl 4-(2-(3,4-dichlorophenyl)acetyl)-3-(pyrrolidin-1-ylmethyl)piperazine-1-carboxylate fumarate; (R)-(-)-GR103545 fumarate. CAS No. 126766-43-6. Molecular formula: C23H29Cl2N3O7. Mole weight: 530.40.
GR 103691
GR 103691 is a potent dopamine D3 receptor antagonist. Uses: Dopamine antagonists. Synonyms: GR 103691; GR103691; GR-103691; 4'-Acetyl-N-[4-[4-(2-methoxyphenyl)-1-piperazinyl]butyl]-[1,1'-biphenyl]-4-carboxamide. Grade: 99%. CAS No. 162408-66-4. Molecular formula: C30H35N3O3. Mole weight: 485.62.
GR 113808 is a potent and selective 5-HT4 receptor antagonist (pKB = 9.43 in human colonic muscle, Kd=0.15 nM for binding to cloned human 5-HT4 receptors). GR 113808 displays > 300-fold selectivity for 5-HT4 over 5-HT1A, 5-HT1B, 5-HT2A, 5-HT2C and 5-HT3 receptors. Uses: Serotonin antagonists. Synonyms: GR 113808; GR113808; GR-113808. 1-methyl-1H-indole-3-carboxylic acid, [1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]methyl ester. Grade: ≥98% by HPLC. CAS No. 144625-51-4. Molecular formula: C19H27N3O4S. Mole weight: 393.5.
GR113808 (5-HT4 Serotonin Receptor Antagonist, GR113808, GR 113808, GR-113808)
A potent and selective antagonist of the serotonin 5-HT4 receptor (pki = 9.3-10.3). GR113808 is commonly used in brain and peripheral in vitro and in vivo in striatum studies (Guinea pig IC50 = 113nM, rat brain membrane Kd = 0.4-1nM) and in cAMP response in CHO and C6 glial cells (EC50 = 79-81nM). Group: Biochemicals. Grades: Highly Purified. CAS No. 144625-51-4. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?S. US Biological Life Sciences.
Worldwide
GR 125487-d3 sulfamate
GR 125487-d3 sulfamate is a deuterated salt form of GR 125487, which is a potent 5-HT4 receptor antagonist used for the treatment of gastrointestinal motility. Synonyms: 5-Fluoro-2-methoxy-d3-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylate sulfamate. Grade: 96% by HPLC; 99% atom D. Molecular formula: C19H23D3FN3O5S.H2NSO3H. Mole weight: 527.6.
GR 125487 sulfamate
GR 125487, a potent and selective 5-HT4 antagonist, is used in many biological assays to cross confirm the 5-HT4R agonist's activity. Synonyms: GR 125487 sulfamate; GR 125487; GR125487; GR-125487. 5-Fluoro-2-methoxy-[1-[2-[(methylsulfonyl)amino]ethyl]-4-piperidinyl]-1H-indole-3-methylcarboxylate sulfamate. Grade: ≥97% by HPLC. CAS No. 859502-43-5. Molecular formula: C19H26FN3O5S.H2NSO3H. Mole weight: 524.58.
GR-125743
GR-125743 is a novel 5-HT1B/1D receptor antagonist, with pKis of 8.85 and 8.31 for wild-type h5-HT1B and wild-type h5-HT1D, respectively. It is used for the research of Parkinson's disease and cardiovascular diseases. Synonyms: N-(4-methoxy-3-(4-methylpiperazin-1-yl)phenyl)-3-methyl-4-(pyridin-4-yl)benzamide; GR 125743. Grade: >99%. CAS No. 148547-33-5. Molecular formula: C25H28N4O2. Mole weight: 416.52.
GR 127935
GR 127935 is a potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors), exhibiting >100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Uses: Serotonin antagonists. Synonyms: [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-; N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxamide; GR127935; GR-127935. Grade: ≥95%. CAS No. 148672-13-3. Molecular formula: C29H31N5O3. Mole weight: 497.59.
GR 127935 hydrochloride
GR 127935 hydrochloride is a potent and selective 5-HT1B/1D receptor antagonist (pKi = 8.5 for both guinea pig 5-HT1D and rat 5-HT1B receptors), exhibiting > 100-fold selectivity over 5HT1A, 5-HT2A, 5-HT2C receptors and other receptor types. Synonyms: [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, hydrochloride (1:1); [1,1'-Biphenyl]-4-carboxamide, N-[4-methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)-, monohydrochloride; N-[4-Methoxy-3-(4-methyl-1-piperazinyl)phenyl]-2'-methyl-4'-(5-methyl-1,2,4-oxadiazol-3-yl)[1,1'-biphenyl]-4-carboxamide hydrochloride; GR127935 hydrochloride; GR-127935 hydrochloride. Grade: ≥99% by HPLC. CAS No. 148642-42-6. Molecular formula: C29H31N5O3.HCl. Mole weight: 534.06.
GR127935 hydrochloride
GR127935 hydrochloride is a potent and orally active 5-HT1D and 5-HT1B receptor antagonist with pKis of 8.5 for both isoforms. GR127935 hydrochloride has 100-fold selectivity for 5-HT1B/1D receptors over 5-HT1A, 5-HT2A, and 5-HT2C receptors. GR127935 hydrochloride can be used in neurological disease research [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 148642-42-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-100794.
GR 127935 Hydrochloride (5-HT1B/1D Serotonin Receptor Antagonist, GR 127935 Hydrochloride, GR-127935 Hydrochloride, GR127935 Hydrochloride)
A selective 5-HT1B/1D receptor antagonist. Selectivity was found to be similar for B (pki = 9.2-9.8) and D (pki = 8.6-9.1) receptor types. GR 127935 works well in vivo and was shown to block (+)-MDMA-induced hyperactivity in rats. It alters release of serotonin in the brain, as well as reducing drug-seeking behavior in cocaine addicted rats. In transformed rat C5 glioma cells, this inhibitor blocked 5HT with an IC50 = 97pM. Group: Biochemicals. Grades: Highly Purified. CAS No. 148642-42-6. Pack Sizes: 10mg. Molecular Formula: C??H??N?O?·HCl. US Biological Life Sciences.
A novel antifungal antibiotic GR 135402 has been isolated from a Graphium putredinis which inhibited protein synthesis in Candida albicans but not rabbit reticulocytes. Synonyms: Antibiotic GR135402; GR135402. CAS No. 204199-15-5. Molecular formula: C34H48O9. Mole weight: 600.74.
GR 135531
GR 135531 is a high affinity agonist of MT3 melatonin receptors, with low affinity for MT1 and MT2 melatonin receptors. GR 135531 can be used to discriminate between the melatonin receptor subtypes. Synonyms: GR 135531; GR135531; GR-1355315-Methoxycarbonylamino-N-acetyltryptamine; 5-MCA-NAT; methyl N-[3-(2-acetamidoethyl)-1H-indol-5-yl]carbamate. Grade: ≥97% by HPLC. CAS No. 190277-13-5. Molecular formula: C14H17N3O3. Mole weight: 275.31.
GR 135531
GR 135531. Group: Biochemicals. Grades: Purified. CAS No. 190277-13-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GR 144053 trihydrochloride
GR 144053 trihydrochloride is a potent and selective orally bioactive platelet fibrinogen receptor glycoprotein IIb/IIIa (GpIIb/IIIa) antagonist (IC50 = 37 nM). GR 144053 potently inhibits thrombus formation in vivo. Synonyms: GR 144053; GR-144053; GR144053; GR 144053 trihydrochloride. 4-[4-[4-(Aminoiminomethyl)phenyl]-1-piperazinyl]-1-piperidineacetic acid trihydrochloride. Grade: ≥99% by HPLC. CAS No. 1215333-48-4. Molecular formula: C18H27N5O2.3HCl. Mole weight: 454.83.
GR 144053 trihydrochloride
GR 144053 trihydrochloride. Group: Biochemicals. Grades: Purified. CAS No. 1215333-48-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GR 159897
GR 159897 is a potent and selective neurokinin NK2 receptor antagonist. GR 159897 competes for binding of [3H]GR100679 to hNK2-transfected CHO cells (pKi = 9.5). Study shows that GR 159897 inhibits NK2 receptor-mediated contraction of guinea pig trachea. Synonyms: GR 159897; GR159897; GR-159897; 5-Fluoro-3-[2-[4-methoxy-4-[[(R)-phenylsulphinyl]methyl]-1-piperidinyl]ethyl]-1H-indole. Grade: ≥97% by HPLC. CAS No. 158848-32-9. Molecular formula: C23H27FN2O2S. Mole weight: 414.54.
GR 203040 is a selective NK1 receptor antagonist with high affinity. GR 203040 potently inhibits substance P binding to NK1 receptors (pKi = 10.1 to 10.5). Synonyms: (2S,3S)-N-[[2-Methoxy-5-(1H-tetrazol-1-yl)phenyl]methyl]-2-phenyl-3-piperidinamine dihydrochloride. Grade: ≥98% by HPLC. CAS No. 168398-02-5. Molecular formula: C20H24N6O·2HCl. Mole weight: 437.37.
GR 231118
GR 231118 is a potent neuropeptide Y (NPY) Y1 receptor antagonist (pA2 = 10 and 10.5 at rY1 and hY1 receptors, respectively) and an NPY Y4 receptor agonist (pEC50 = 6.0, 8.6 and 6.1 for rY2, hY4 and rY5 receptors, respectively). GR 231118 inhibits food intake in rats in vivo. Synonyms: GR-231118; GR 231118; GR231118. Grade: >99%. CAS No. 158859-98-4. Molecular formula: C110H170N34O24. Mole weight: 2352.77.
GR 231118
GR 231118. Group: Biochemicals. Grades: Purified. CAS No. 158859-98-4. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
GR24
(Rac)-GR24 (Strigolactone GR24) is a plant hormone analog. (Rac)-GR24 can mimic the natural germination stimulus of parasitic plant seeds, promoting seed germination in the absence of host plants, thereby reducing the number of parasitic seeds in the soil. (Rac)-GR24 can be used in agricultural research [1]. Uses: Scientific research. Group: Biochemical assay reagents. Alternative Names: Strigolactone GR24. CAS No. 76974-79-3. Pack Sizes: 5 mg; 10 mg. Product ID: HY-129038.
GR 46611 is a 5-HT1D receptor agonist that may be beneficial for the treatment of migraine. 5-HT1D acts on the central nervous system. Synonyms: GR 46611; GR46611; GR-46611; 3-[3-(2-Dimethylaminoethyl)-1H-indol-5-yl]-N-(4-methoxybenzyl)acrylamide. CAS No. 185259-85-2. Molecular formula: C23H27N3O2. Mole weight: 377.49.
GR 49336
A metabolite of Sumatriptan. Group: Biochemicals. Alternative Names: 5-[[ (Methylamino) sulfonyl]methyl]-. Grades: Highly Purified. CAS No. 103628-44-0. Pack Sizes: 2.5mg. US Biological Life Sciences.
Worldwide
GR 49336
GR 49336. Uses: Designed for use in research and industrial production. Additional or Alternative Names: 5-[[(Methylamino)sulfonyl]methyl]-1H-indole-3-acetic Acid. Product Category: Heterocyclic Organic Compound. CAS No. 103628-44-0. Molecular formula: C12H14N2O4S. Mole weight: 282.32. Purity: 0.96. IUPACName: 2-[5-(methylsulfamoylmethyl)-1H-indol-3-yl]acetic acid. Canonical SMILES: CNS(=O)(=O)CC1=CC2=C(C=C1)NC=C2CC(=O)O. Density: 1.471g/cm³. Product ID: ACM103628440-1. Alfa Chemistry ISO 9001:2015 Certified.
GR5
GR5. Synonyms: (E)-3-(((4-methyl-5-methylene-2,5-dihydrofuran-2-yl)oxy)methylene)dihydrofuran-2(3H)-one. Grade: >95% by HPLC.
GR 55562 dihydrochloride
GR 55562 dihydrochloride is a selective and competitive 5-HT1B (5-HT1Dβ) silent antagonist (pKB values of 7.3 and 6.3 for human cloned 5-HT1B and 5-HT1D receptors, respectively). Synonyms: GR 55562 dihydrochloride; GR-55562; GR55562; GR 55562. 3-[3-(Dimethylamino)propyl]-4-hydroxy-N-[4-(4-pyridinyl)phenyl]benzamide dihydrochloride. Grade: ≥98% by HPLC. CAS No. 159533-25-2. Molecular formula: C23H25N3O2.2HCl. Mole weight: 448.39.
GR 55562 hydrochloride
GR 55562 hydrochloride is a selective 5-HT 1B receptor antagonist. GR 55562 hydrochloride can be used for the research of nerve disease [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 172854-55-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-W010869.
GR 64349
GR 64349 is a potent and selective agonist of tachykinin NK2 receptor (EC50 = 3.7 nM in rat colon). Synonyms: GR 64349; GR64349; GR-64349; LYS-ASP-SER-PHE-VAL-GLY-R-GAMMA-LACTAM-LEU-MET-NH2; [LYS3, GLY8-R-GAMMA-LACTAM-LEU9]NEUROKININ A (3-10); L-Lys-L-Asp-L-Ser-L-Phe-L-Val-N-[(3R)-1-[(R)-1-[[[(S)-1-(Aminocarbonyl)-3-(methylthio)propyl]amino]carbonyl]-3-methylbutyl]-2-oxo-3α-pyrrolidi. Grade: >98%. CAS No. 137593-52-3. Molecular formula: C42H68N10O11S. Mole weight: 921.12.
GR 64349 TFA
GR 64349 is a potent and selective tachykinin NK2 receptor agonist (EC50 = 3.7 nM in rat colon). Molecular formula: C44H69F3N10O13S. Mole weight: 1035.13.
GR 73632
GR 73632 is a potent and selective tachykinin NK1 receptor agonist (EC50 = 2 nM in guinea pig vas deferens). GR 73632 is able to be used in the treatment of asthma and gastrointestinal disorders. Synonyms: GR-73632; GR 73632; GR73632. Delta-Aminovaleryl-9-pro-10-meleu-substance P (7-10); Substance P (7-10), delta-aminovaleryl-pro(9)-N-meleu(10)-; Substance P (7-10), delta-aminovaleryl-prolyl(9)-N-methylleucine(10)-. CAS No. 133156-06-6. Molecular formula: C40H59N7O6S. Mole weight: 766.01.
GR-73632
GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist[1]. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals[2]. Uses: Scientific research. Group: Peptides. CAS No. 133156-06-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1192.
GR 79236
GR 79236, an effective Adenosine A1 receptor agonist, could probably be used as an anti-inflammatory agent. IC50: 3.1 nM(Ki). Uses: Gr 79236 is an effective adenosine a1 receptor agonist that could probably be used as an anti-inflammatory agent. Synonyms: GR79236; GR-79236; GR 79236. N-[(1S, trans)-2-Hydroxycyclopentyl]adenosine. Grade: 95%. CAS No. 124555-18-6. Molecular formula: C15H21N5O5. Mole weight: 351.36.
GR 82334 is a tachykinin NK1 receptor antagonist. Synonyms: GR-82334; GR 82334; GR82334; Physalaemin(1-11), D-pro(9)(spiro-gamma-lactam)leu(10)-trp(11)-; Physalemin, 9-deglycine-10-((5S)-6-oxo-L-alpha-(2-methylpropyl)-1,7-diazaspiro(4.4)nonane-7-acetic acid)-11-L-tryptophanamide-. Grade: >98%. CAS No. 129623-01-4. Molecular formula: C69H91N15O16. Mole weight: 1386.57.
GR 89696
GR 89696 is a highly selective κ2 opioid receptor agonist with potential to prevent pruritus [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 126766-32-3. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-107747.
GR 89696 fumarate
GR 89696 fumarate. Group: Biochemicals. Grades: Purified. CAS No. 126766-32-3. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GR 89696 fumarate
GR 89696 fumarate is a potent and selective κ-opioid agonist (IC50 = 0.04 nM) displaying anti-nociceptive and neuroprotective activity. Synonyms: GR 89696 fumarate; GR 89696; GR89696; GR-89696. 4-[(3,4-Dichlorophenyl)acetyl]-3-(1-pyrrolidinylmethyl)-1-piperazinecarboxylic acid methyl ester fumarate. Grade: ≥99% by HPLC. CAS No. 126766-32-3. Molecular formula: C19H25Cl2N3O3.C4H4O4. Mole weight: 530.4.