A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
GNF 5. Group: Biochemicals. Grades: Purified. CAS No. 778277-15-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GNF-5
GNF-5 is the N-hydroxyethyl carboamide analog of GNF-2, a selective allosteric inhibitor of Bcr-Abl. GNF-5 demonstrates IC50 values of 4.52, 0.38, and 0.93 μM against Bcr-Abl mutants G250E, E255V, and M351T, respectively. Synonyms: GNF-5; GNF 5; GNF5. CAS No. 778277-15-9. Molecular formula: C20H17F3N4O3. Mole weight: 418.38.
GNF-5
GNF-5, the N-hydroxyethyl carboxamide analog of GNF-2, is an orally active Bcr-Abl inhibitor. GNF-5 has Bcr-Abl inhibition activity with an IC50 value of 0.22 μM. GNF-5 has good favorable pharmacokinetic properties. GNF-5 can be used for the research of kinds of cancer including chronic myelogenous leukemia (CML) and breast cancer[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 778277-15-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15738.
GNF 5837
GNF 5837 is a potent and selective pan-Trk inhibitor that blocks tumor gowth in a mouse xenograft model derived from RIE cells expressing both TRKA and NGF. GNF 5837 displays antiproliferative effects in cellular Ba/F3 assays with IC50 values of 7, 9 and 11 nM for cells expressing Tel-TrkC, Tel-TrkB and Tel-TrkA respectively. Synonyms: GNF5837; GNF-5837; GNF 5837. 1-[2-fluoro-5-(trifluoromethyl)phenyl]-3-[4-methyl-3-[[(3Z)-2-oxo-3-(1H-pyrrol-2-ylmethylidene)-1H-indol-6-yl]amino]phenyl]urea. CAS No. 1033769-28-6. Molecular formula: C28H21F4N5O2. Mole weight: 535.503.
GNF 5837
GNF 5837. Group: Biochemicals. Grades: Purified. CAS No. 1033769-28-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
GNF-5837
GNF-5837 is a potent, selective, and orally bioavailable pan-tropomyosin receptor kinase (TRK) inhibitor which display antiproliferative effects in cellular Ba/F3 assays ( IC50 values of 7 nM, 9 nM and 11 nM for cells containing the fusion proteins Tel-TrkC, Tel-TrkB and Tel-TrkA, respectively) [1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1033769-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13491.
GNF-6231
GNF-6231 is a porcupine (IC50= 0.8 nM), Pron, and endoplasmic reticulum protein inhibitor with oral activity. GNF-6231 has anticancer activity. GNF-6231 can prevent the activation of the Wnt pathway by blocking the secretion of all Wnt ligands. GNF-6231 can be used in the study of myocardial infarction[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1243245-18-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100408.
GNF-6231
GNF-6231 is a potent porcupine inhibitor that blocks Wnt signaling. GNF-6231 exhibits potential antitumor properties via inhibition of aberrant Wnt signaling. Synonyms: [2,4'-Bipyridine]-5-acetamide, N-[5-(4-acetyl-1-piperazinyl)-2-pyridinyl]-2'-fluoro-3-methyl-; N-[5-(4-Acetyl-1-piperazinyl)-2-pyridinyl]-2'-fluoro-3-methyl[2,4'-bipyridine]-5-acetamide; GNF 6231; GNF6231; N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2'-fluoro-3-methyl-[2,4'-bipyridin]-5-yl)acetamide. Grade: >98%. CAS No. 1243245-18-2. Molecular formula: C24H25FN6O2. Mole weight: 448.49.
GNF-7
GNF-7 is a type-II T315I inhibitor. GNF-7 inhibits Ack1 and germinal center kinase (GCK). GNF-7 is among the first type-II inhibitors capable of inhibiting T315I to be described and will serve as a valuable lead to design the third generation Bcr-Abl kinase inhibitors. Uses: Protein kinase inhibitors. Synonyms: GNF7; GNF 7; N-(4-methyl-3-(1-methyl-7-((6-methylpyridin-3-yl)amino)-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl)phenyl)-3-(trifluoromethyl)benzamide. Grade: 98%. CAS No. 839706-07-9. Molecular formula: C28H24F3N7O2. Mole weight: 547.54.
GNF-7
GNF-7 is a multikinase inhibitor. GNF-7 is a Bcr-Abl inhibitor, with IC50s of 133 nM and 61 nM for Bcr-AblWT and Bcr-AblT315I, respectively. GNF-7 also possesses inhibitory activity against both ACK1 (activated CDC42 kinase 1) and GCK (germinal center kinase) with IC50s of 25 nM and 8 nM, respectively. GNF-7 can be used for the research of hematologic malignancies[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 839706-07-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10943.
GNF-8625 monopyridin-N-piperazine hydrochloride
GNF-8625 monopyridin-N-piperazine hydrochloride is a TRK inhibitor. (Extracted from the patent WO 2020038415 A1). Synonyms: TRKi-2; (R)-6-(2-(3-fluorophenyl)pyrrolidin-1-yl)-3-(6-(piperazin-1-yl)pyridin-2-yl)imidazo[1,2-b]pyridazine hydrochloride. CAS No. 2412055-62-8. Molecular formula: C25H27ClFN7. Mole weight: 479.98.
G-NGA2 N-Glycan
G-NGA2 N-Glycanthe transformative compound engaging in protein modifications. It finds applications in studying glycosylation-related disorders and diseases. Synonyms: Monogalactosylated asialo, biantennary (G-NGA2); Monogalactosylated, asialo, bi-antennary N-linked glycan; Monogalactosylated, asialo, biantennary N-glycan (G-NGA2); O-2-(Acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-2)-O-alpha-D-mannopyranosyl-(1-6)-O-[O-beta-D-galactopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-2)-alpha-D-mannopyranosyl-(1-3)]-O-beta-D-mannopyranosyl-(1-4)-O-2-(acetylamino)-2-deoxy-beta-D-glucopyranosyl-(1-4)-2-(acetylamino)-2-deoxy-D-glucose. Grade: ≥90%. CAS No. 103584-68-5. Molecular formula: C56H94N4O41. Mole weight: 1479.35.
GNQWFI
GNQWFI, an anti-Flt1 peptide, is a VEGFR1-specific antagonist. GNQWFI blocks the interaction of VEGFR1 with various VEGFR1 ligands, such as VEGFA, VEGFB, and placental growth factor (PIGF) and inhibits VEGF-induced endothelial cell migration and tube formation. GNQWFI is promising for research of cancer, asthma, and other ocular diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 853995-60-5. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-P10831.
GnRH antagonist 2
GnRH antagonist 2, a GnRH receptor antagonist, can be used in the study of endometriosis. Synonyms: Urea, N-[4-[7-[(2,6-difluorophenyl)methyl]-3-[(dimethylamino)methyl]-4,5,6,7-tetrahydro-5-(6-methoxy-3-pyridazinyl)-4,6-dioxo-2H-pyrazolo[3,4-d]pyrimidin-2-yl]phenyl]-N'-methoxy-. Grade: ≥98%. CAS No. 1709823-61-9. Molecular formula: C28H27F2N9O5. Mole weight: 607.57.
GnRH Associated Peptide (GAP) (1-13), human
GnRH Associated Peptide (GAP) (1-13), human is a potent inhibitor of prolactin secretion and stimulates the release of gonadotropins. Active immunization with peptides corresponding to the GAP sequences can significantly increase prolactin secretion. Synonyms: L-Valine, L-α-aspartyl-L-alanyl-L-α-glutamyl-L-asparaginyl-L-leucyl-L-isoleucyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-glutaminyl-L-α-glutamyl-L-isoleucyl-; L-α-Aspartyl-L-alanyl-L-α-glutamyl-L-asparaginyl-L-leucyl-L-isoleucyl-L-α-aspartyl-L-seryl-L-phenylalanyl-L-glutaminyl-L-α-glutamyl-L-isoleucyl-L-valine; H-Asp-Ala-Glu-Asn-Leu-Ile-Asp-Ser-Phe-Gln-Glu-Ile-Val-OH. Grade: 95%. CAS No. 100111-07-7. Molecular formula: C65H101N15O25. Mole weight: 1492.58.
GnRH Associated Peptide (GAP) (1-13), human acetate
GnRH Associated Peptide (GAP) (1-13), human acetate is a potent inhibitor of prolactin secretion and stimulates the release of gonadotropins. Active immunization with peptides corresponding to the GAP sequences can significantly increase prolactin secretion. Synonyms: H-Asp-Ala-Glu-Asn-Leu-Ile-Asp-Ser-Phe-Gln-Glu-Ile-Val-OH.CH3CO2H; L-alpha-aspartyl-L-alanyl-L-alpha-glutamyl-L-asparagyl-L-leucyl-L-isoleucyl-L-alpha-aspartyl-L-seryl-L-phenylalanyl-L-glutaminyl-L-alpha-glutamyl-L-isoleucyl-L-valine acetic acid. Grade: ≥95%. Molecular formula: C67H105N15O27. Mole weight: 1552.63.
GnRH II trifluoroacetate salt
GnRH II is a peptide that is encoded by the GNRH2 gene in humans. It acts as an agonist of the GnRH receptor (GnRHR). Synonyms: Gonadotropin-releasing Hormone II; ?LHRH II; 5-oxo-L-prolyl-L-histidyl-L-tryptophyl-L-seryl-L-histidylglycyl-L-tryptophyl-L-tyrosyl-L-prolyl-glycinamide, trifluoroacetate salt. Grade: ≥95%. Molecular formula: C60H69N17O13·xCF3COOH. Mole weight: 1236.30.
GNX-865
GNX-865 is a mitochondrial permeability transition pore (mPTP) inhibitor that protects against ischemia-reperfusion injury in vivo[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1223568-82-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-119909.
GO-203 TFA
GO-203 is a D-amino acid cell-penetrating peptide inhibitor of MUC1-C dimerization and thereby its oncogenic function. Group: Inhibitors. CAS No. 1222186-26-6. Pack Sizes: 2mg. Product ID: S8674. Formula: C87H170N52O19S2.C2HF3O2. Smiles: C(CCN)CC(C(=O)NC(CC(=O)N)C(=O)O)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CS)NC(=O)C(CCC(=O)N)NC(=O)C(CS)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)NC(=O)C(CCCNC(=N)N)N.C(=O)(C(F)(F)F)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
GO-203 TFA
GO-203 TFA is a potent MUC1-C oncoprotein inhibitor. GO-203 TFA is an all D-amino acid peptide that consists of a poly-R transduction domain linked to a CQCRRKN motif that binds to the MUC1-C cytoplasmic tail and blocks MUC1-C homodimerization. GO-203 TFA downregulates TIGAR (TP53-induced glycolysis and apoptosis regulator) protein synthesis by inhibiting the PI3K-AKT-S6K1 pathway. GO-203 TFA induces the production of ROS and loss of mitochondrial transmembrane potential. GO-203 TFA inhibits the growth of colon cancer cells in vitro and as xenografts in nude mice[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1222186-26-6. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P1925A.
Go6976
Go6976 is a Protein Kinase C (PKC) inhibitor, with an IC50 of 20 nM. Uses: Scientific research. Category: Signaling pathways. CAS No. 136194-77-9. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10183.
Go 6976
Go 6976. Group: Biochemicals. Grades: Purified. CAS No. 136194-77-9. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
GO-6976
Go6976 is a potent PKC inhibitor with IC50 values of 2.3 and 6.2 nM for PKCα and PKCβ1, respectively. It also inhibits TrkA, TrkB, JAK2 and JAK3 tyrosine kinases (IC50 values are 5, 30, 130 and 370 nM respectively). Synonyms: GO-6976; GO 6976; PD-406976; PD 406976; PD406976. Grade: >98%. CAS No. 136194-77-9. Molecular formula: C24H18N4O. Mole weight: 378.435.
Cell-permeable. A potent protein kinase C (PKC) inhibitor (IC50 = 7.9nM). In vitro, discriminates between Ca2+- dependent and -independent isoforms of PKC; selectively inhibits PKC alpha and PKC beta1 (IC50 values are 2.3 and 6.2 nM respectively) but does not inhibit the activity of PKCδ, -ε, or -ζ (IC50 > 3μM). Group: Biochemicals. Alternative Names: 5,6,7,13-Tetrahydro-13-methyl-5-oxo-12H-indolo[2,3-a]py-rrolo[3,4-c]carbazole-12-propanenitrile; Go6976; PD 406976. Grades: Highly Purified. CAS No. 136194-77-9. Pack Sizes: 500ug. US Biological Life Sciences.
Worldwide
Go6983
GO6983 is a potent protein kinase C (PKC) inhibitor. GO6893 displays cardioprotective properties; reduces polymorphonuclear leukocyte adherence and infiltration following myocardial ischemia/reperfusion injury. Synonyms: Go6983, Go-6983; Go 6983; GO6983. Grade: >98%. CAS No. 133053-19-7. Molecular formula: C26H26N4O3. Mole weight: 442.519.
Go 6983
Go 6983. Group: Biochemicals. Alternative Names: 3-[1-[3-(Dimethylamino)propyl]-5-methoxy-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione; Goe 6983. Grades: Highly Purified. CAS No. 133053-19-7. Pack Sizes: 1mg. Molecular Formula: C26H26N4O3, Molecular Weight: 442.51. US Biological Life Sciences.
Worldwide
Go 6983
Go 6983 is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ, PKCδ and PKCζ with IC50 of 7 nM, 7 nM, 6 nM, 10 nM and 60 nM, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Gö 6983; Goe 6983. CAS No. 133053-19-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13689.
Go 6983
Go 6983 (GOE 6983, Gö 6983) is a pan-PKC inhibitor against for PKCα, PKCβ, PKCγ and PKCδ with IC50 of 7 nM, 7 nM, 6 nM and 10 nM, respectively; less potent to PKCζ and inactive to PKCμ. Group: Inhibitors. Alternative Names: GOE 6983, Gö 6983. CAS No. 133053-19-7. Pack Sizes: 10mg. Product ID: S2911. Formula: C26H26N4O3. Smiles: CN(C)CCCN1C=C(C2=C1C=CC(=C2)OC)C3=C(C(=O)NC3=O)C4=CNC5=CC=CC=C54. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Goadsporin
It is produced by the strain of Streptomyces sp. TP-A0584. It can promote the secondary metabolism and morphogenesis of Streptomyces, and it is a tool to analyze the regulatory mechanism of Streptomyces. CAS No. 883434-90-0. Molecular formula: C72H97N19O20S2. Mole weight: 1612.78.
Goat's Rue Herb Powder
Goat's Rue Herb Powder.
CA, FL & NJ
GoatThroat Pump EPDM Seal GT200
The GoatThroat GT200 is a pump for liquid transferring that has a EPDM (Ethylene Propylene Diene Monomer) seal. Pumps help workers stay safe by reducing or completely eliminating spills. GoatThroat pumps are compatible with many different chemicals and viscosities. This durable pump will last you a long time if properly used. Uses: Transfer of liquids. Grades: Food Grade. Pack Sizes: 1. Categories: Goat Throat pumps.
USA
GoatThroat Pump Nitrile Seal GT100
The GoatThroat GT100 is a pump for transferring liquids that has a nitrile seal. Depending on the viscosity of the liquid, this pump can dispense 4 gallons every minute. Just like gloves or goggles, an effective pump can be one of the best pieces of PPE in the workplace. GoatThroat pumps are known for their durability over time and consistent safe usage. Uses: Transfer of liquids. Grades: Food Grade. Pack Sizes: 1. Categories: Goat Throat pumps.
USA
GoatThroat Pump Viton Seal GT300
The GoatThroat GT300 is a pump for transferring different kinds of liquids that has a viton seal. It can fit almost any container from a 2-gallon jug to a 55-gallon drum. Dispensing is as easy as turning on a faucet! GoatThroat pumps are some of the best, safest, most efficient, and affordable pumps out there. Uses: Transfer of liquids. Grades: Food Grade. Pack Sizes: 1. Categories: Goat Throat pumps.
USA
Gocatamig
HY-P990920 is an CD3E/ALB/DLL3-targeting (scFv-heavy-lamdba)-VH-VH' type chimeric humanized antibody[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MK-6070; HPN328. CAS No. 2851862-91-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P990920.
Goitrin
Goitrin. Group: Biochemicals. CAS No. 13190?-?34?-?6?. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Goji Berry Extract
Goji berry extract is prepared from Lycium chinense, common plants of eastern Asia. Goji berry extract also known as wolfberry extract is rich of polysaccharides, all kinds of vitamins and 19 kinds of amino acid, as well as 21 kinds of minerals. Goji berry extract powder has the functions of preventing & curing cancers, strengthening hematopoiesis, nourishing liver, lowering blood pressure and promoting cell activity. Goji berry extract powder has been widely used in pharmacy manufacture and healthy food processing. Group: Others. Goji Berry Extract; Lycium Chinense Miller. Cat No: EXTC-005.
Goji Berry Powder
Goji berry juice powder also called wolfberry powder, is a bright orange fine powder that comes from a shrub fresh goji berry that is native to China. Goji berry juice powder is used to treat many common health problems, like diabetes, high bloood pressure, fever, and age reated eye problems. Goji berry Powder is a rich source of nutrients and amino acids. It contains 18 amino acids, 21 trace miner also several vitamins and minerals. Group: Others. Goji Berry Powder; Lycium barbarum L. Cat No: EXTC-086.
Golcadomide (CC-99282) is a potent and orally active CRBN E3 ligase modulator (CELMoD). Golcadomide interacts with the CRL4 CRBN E3 ubiquitin ligase substrate receptor CRBN, inducing the recruitment and ubiquitin-mediated proteasomal degradation of the transcription factors Ikaros and Aiolos. Golcadomide shows potential for research in cancer-related fields, including chronic lymphocytic leukemia (CLL) and non-Hodgkin lymphoma (NHL)[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CC-99282. CAS No. 2379572-34-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-146237.
Gold-coloured powder or tiny sheets;Soft yellow metal; gold-colored powder or tiny sheets. CAS No. 7440-57-5. Molecular formula: Au. Mole weight: 196.96657g/mol. IUPAC Name: gold. SMILES: [Au]. InChI: 1S/Au.
Gold coated silicon wafer
The product is highly crystalline, with <111> orientation gold and <100> orientation silicon wafer is used. Titanium is used as an adhesion layer to bind gold to the silicon wafer. Molecular formula: Au. SMILES: [Au]. InChI: 1S/Au.
Golden Rod Extract. Applications: Used for health care products, dietary supplements, herb medecine, mainly for anti-inflammatory. Group: Others. Synonyms: Golden Rod Extract; 90045-39-9; Solidago virgaurea L. CAS No. 90045-39-9. Purity: 4-10:1 by TLC. Appearance: Brown fine powder. Storage: 2 years under well storage situation and stored away from direct sun light. Source: Flower. Species: Solidago virgaurea L. Golden Rod Extract; 90045-39-9; Solidago virgaurea L.; plant extract. Pack: 25KG/Drum with double plastic bag of foodstuff inside. Cat No: EXTW-132.
Golden Scaffold Library
Diversity: Selected from 1, 600, 000 drug-like compounds, 10000 compounds representing 5000 scaffolds selected from a large drug-like chemical source?- Drug-likeness: filtering out reactive, toxic and otherwise undesirable structural motifs, and removing compounds that demonstrate a broad promiscuous activity (PAINS); - Strict quality control: more than 90% purity for each member with HNMR/LCMS validation?- Cost effective: Liquid small package is available. (Can be purchased together with Mini scaffolds library?forming a diversity library with more broad coverage. ). Uses: Scientific use. Product Category: L5610. Categories: Golden Scaffold Libraries.