A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Histidyl-asparagine is a dipeptide composed of histidine and asparagine. CAS No. 158691-82-8. Molecular formula: C10H15N5O4. Mole weight: 269.26.
Histidyl-isoleucine
Histidyl-isoleucine is a peptide which functions as a hormone. Alternative Names: L-histidyl-L-isoleucine; His-Ile; HI dipeptide. CAS No. 129050-48-2. Molecular formula: C12H20N4O3. Mole weight: 268.31.
Histidyl-lysine
Histidyl-lysine. Alternative Names: L-histidyl-L-lysine. CAS No. 37700-85-9. Molecular formula: C12H21N5O3. Mole weight: 283.33.
Histidyl-proline
Histidyl-proline is a dipeptide formed from L-histidine and L-proline residues. Alternative Names: L-Histidyl-L-proline; His-pro. Grades: >95%. CAS No. 20930-58-9. Molecular formula: C11H16N4O3. Mole weight: 252.27.
Histidyl-threonine
Histidyl-threonine is a dipeptide composed of histidine and threonine. CAS No. 142879-28-5. Molecular formula: C10H16N4O4. Mole weight: 256.26.
Histidyl-tRNA Synthetase from Human, Recombinant
Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Histidyl-trna synthetase human recombinant produced in.thetase is purified by proprietary chromatographic techniques. Group: Enzymes. Synonyms: Histidyl-tRNA synthetase; EC 6.1.1.21; Histidine-tRNA ligase; HisRS; HRS; FLJ20491; JO-1. Enzyme Commission Number: EC 6.1.1.21. CAS No. 9068-78-4. Purity: Greater than 90.0% as determined by both (a) Analysis by RP-HPLC. (b) Analysis by SDS-PAGE. HRS. Stability: Histidyl-tRNA Synthetase although stable at 4°C for 3 weeks, should be stored desiccated below -18°C. Please prevent freeze-thaw cycles. Appearance: Sterile Filtered clear solution. Source: E. coli. Species: Human. Histidyl-tRNA synthetase; EC 6.1.1.21; Histidine-tRNA ligase; HisRS; HRS; FLJ20491; JO-1. Cat No: NATE-0848.
Histidyl-Valine
Histidyl-Valine is a dipeptide composed of histidine and valine. It is an incomplete breakdown product of protein digestion or protein catabolism. Alternative Names: H-HV-OH; L-histidyl-L-valine; His-Val; Histidylvaline; L-His-L-Val. Grades: ≥95% by HPLC. CAS No. 76019-15-3. Molecular formula: C11H18N4O3. Mole weight: 254.29.
histolysain
From the protozoan, Entamoeba histolytica. In peptidase family C1 (papain family). Group: Enzymes. Synonyms: histolysin; histolysin; Entamoeba histolytica cysteine proteinase; amebapain; Entamoeba histolytica cysteine protease; Entamoeba histolytica neutral thiol proteinase. Enzyme Commission Number: EC 3.4.22.35. CAS No. 92228-52-9. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4210; histolysain; EC 3.4.22.35; 92228-52-9; histolysin; histolysin; Entamoeba histolytica cysteine proteinase; amebapain; Entamoeba histolytica cysteine protease; Entamoeba histolytica neutral thiol proteinase. Cat No: EXWM-4210.
histone acetyltransferase
A group of enzymes with differing specificities towards histone acceptors. Group: Enzymes. Synonyms: nucleosome-histone acetyltransferase; histone acetokinase; histone acetylase; histone transacetylase. Enzyme Commission Number: EC 2.3.1.48. CAS No. 9054-51-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-2227; histone acetyltransferase; EC 2.3.1.48; 9054-51-7; nucleosome-histone acetyltransferase; histone acetokinase; histone acetylase; histone transacetylase. Cat No: EXWM-2227.
Histone Acetyltransferase Inhibitor II
Histone Acetyltransferase Inhibitor II (compound 2c) is a potent, selective and cell permeable p300 histone acetyltransferase inhibitor, with an IC50 of 5 μM. Histone Acetyltransferase Inhibitor II shows anti-acetylase activity in mammalian cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 932749-62-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100734.
Histone cluster 2, H2bf isoform b (108-126)
Histone cluster 2, H2bf isoform b (108-126).
histone deacetylase
A class of enzymes that remove acetyl groups from N6-acetyl-lysine residues on a histone. The reaction of this enzyme is opposite to that of EC 2.3.1.48, histone acetyltransferase. Histone deacetylases (HDACs) can be organized into three classes, HDAC1, HDAC2 and HDAC3, depending on sequence similarity and domain organization. Histone acetylation plays an important role in regulation of gene expression. In eukaryotes, HDACs play a key role in the regulation of transcription and cell proliferation. May be identical to EC 3.5.1.17, acyl-lysine deacylase. Group: Enzymes. Synonyms: HDAC. Enzyme Commission Number: EC 3.5.1.98. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4490; histone deacetylase; EC 3.5.1.98; HDAC. Cat No: EXWM-4490.
Histone from calf thymus
Histone from calf thymus. CAS No. 9064-47-5. Molecular formula: C141H128Cl5N29O11S. Mole weight: 2614.00.
Histone H1-derived Peptide
Histone H1-derived Peptide is a phosphopeptide and the peptide substrates containes a sequence in accordance with the optimal recognition motif for CDK, can be used to detecting CDK1-cyclinB1 enzyme activity[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 889112-06-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P2480.
Histone H2A
Histone H2A is an antibacterial peptide isolated from Oncorhynchus mykiss. It has activity against bacteria and fungi. Alternative Names: Ala-Glu-Arg-Val-Gly-Ala-Gly-Ala-Pro-Val-Tyr-Leu.
Histone H2B 1 is an antibacterial peptide isolated from Ictalurus punctatus. It has activity against bacteria and fungi. Molecular formula: C85H149N25O24. Mole weight: 2034.62.
Histone H2B 3
Histone H2B 3 is an antibacterial peptide isolated from Ictalurus punctatus. It has activity against bacteria and fungi. Alternative Names: Pro-Asp-Pro-Ala-Lys-Thr-Ala-Pro-Lys-Lys-Lys-Ser-Lys-Lys-Ala-Val-Thr. Molecular formula: C80H143N23O23. Mole weight: 1795.16.
Histone H3 (1-20)
Histone H3 (1-20). Alternative Names: H3 (1-20); H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-OH; L-alanyl-L-arginyl-L-threonyl-L-lysyl-L-glutaminyl-L-threonyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-threonyl-glycyl-glycyl-L-lysyl-L-alanyl-L-prolyl-L-arginyl-L-lysyl-L-glutaminyl-L-leucine. Grades: ≥95% by HPLC. CAS No. 380598-30-1. Molecular formula: C91H167N35O27. Mole weight: 2183.52.
Histone H3 (1-21)
Histone H3 (1-21), derived from Histone H3 1-21 amino acids, is usually used as a substrate for methyltransferase (Histone 3 K4 and K9) and acetyltransferase (Histone 3 K9 and K14) assays[1]. Uses: Scientific research. Category: Peptides. CAS No. 873215-29-3. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P2552.
Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide
Histone H3 (1-21)-Gly-Gly-Lys(biotinyl) amide. Alternative Names: H3 (1-21), biotin-labeled; H-Ala-Arg-Thr-Lys-Gln-Thr-Ala-Arg-Lys-Ser-Thr-Gly-Gly-Lys-Ala-Pro-Arg-Lys-Gln-Leu-Ala-Gly-Gly-Lys(biotinyl)-NH2. CAS No. 2243207-10-3. Molecular formula: C114H205N43O32S. Mole weight: 2722.22.
Histone H3 (21-44)
Histone H3 (21-44) is a histone fragment that is used as a substrate for the protein arginine methyltransferase PRMT4. Alternative Names: H3 (21-44); H-Ala-Thr-Lys-Ala-Ala-Arg-Lys-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-OH; L-Alanyl-L-threonyl-L-lysyl-L-alanyl-L-alanyl-L-arginyl-L-lysyl-L-seryl-L-alanyl-L-prolyl-L-alanyl-L-threonylglycylglycyl-L-valyl-L-lysyl-L-lysyl-L-prolyl-L-histidyl-L-arginyl-L-tyrosyl-L-arginyl-L-prolylglycine. Grades: ≥95%. CAS No. 1373516-71-2. Molecular formula: C109H185N39O29. Mole weight: 2505.91.
Histone H3 (21-44)-Gly-Lys(biotinyl)
Histone H3 (21-44)-Gly-Lys(biotinyl) is a derivative of Histone H3, a fundamental unit of chromatin. Alternative Names: Histone H3 (21-44)-GK(Biotin), biotin-labeled; Ala-Thr-Lys-Ala-Ala-Arg-Lys-Ser-Ala-Pro-Ala-Thr-Gly-Gly-Val-Lys-Lys-Pro-His-Arg-Tyr-Arg-Pro-Gly-Gly-Lys(Biotin). Molecular formula: C127H214N44O33S. Mole weight: 2917.6.
Histone H3.3 (84-98)
Histone H3.3 (84-98) is a truncated fragment of Histone H3.3. Histone 3 family 3 (H3F3) histones (H3.3) mark active genes, maintain epigenetic memory, and maintain heterochromatin and telomeric integrity.
A cell-permeable iron chelating benzisothiazolone compound with microbicide and fungicide properties that acts as a potent, selective, and reversible inhibitor of Jumonji AT-Rich Interactive Domain 1 (JARID1) histone demethylases (IC50 = 3uM for JARID1B). Also blocks the activity of other related demethylases at higher concentration (IC50 = 6, 4.9, and 28uM for JARID1A, JARID1C, and JMJD2E, respectively). However, it does affect the activity of unrelated UTX and JMJD3 H3K27me3 demethylases. HeLa cells overexpressing full length JARID1B show a significant reduction in H3K4Me3 activity following PBIT treatment (~10uM). Blocks the proliferation of UACC-812 tumor cells expressing higher levels of JARDID1B, but does not significantly affect MCF7 or MCF10A cells expressing lower levels of JARDID1B. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 25mg. Molecular Formula: C??H??NOS, Primary Target: JARID1 Histone Demethylases. US Biological Life Sciences.
Worldwide
histone-lysine N-methyltransferase
One of a group of enzymes methylating proteins; see also EC 2.1.1.59, [cytochrome-c]-lysine N-methyltransferase and EC 2.1.1.60, calmodulin-lysine N-methyltransferase. Group: Enzymes. Synonyms: protein methylase III; protein methylase 3; protein (lysine) methyltransferase; protein methyltransferase II; protein-lysine N-methyltransferase; histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase; S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase. Enzyme Commission Number: EC 2.1.1.43. CAS No. 9055-8-7. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1947; histone-lysine N-methyltransferase; EC 2.1.1.43; 9055-08-7; protein methylase III; protein methylase 3; protein (lysine) methyltransferase; protein methyltransferase II; protein-lysine N-methyltransferase; histone H1-specific S-adenosylmethionine:protein-lysine N-methyltransferase; S-adenosyl-L-methionine:histone-L-lysine 6-N-methyltransferase. Cat No: EXWM-1947.
Histone-lysine N-methyltransferase EZH2 (120-128)
Histone-lysine N-methyltransferase EZH2 (120-128) is a bioactive peptide of Histone-lysine N-methyltransferase EZH2. Compared to EZH1-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Alternative Names: ENX-1 (120-128); Enhancer of zeste homolog 2 (120-128); Lysine N-methyltransferase 6 (120-128).
Histone-lysine N-methyltransferase EZH2 (165-174)
Histone-lysine N-methyltransferase EZH2 (165-174) is a bioactive peptide of Histone-lysine N-methyltransferase EZH2. Compared to EZH1-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Alternative Names: ENX-1 (165-174); Enhancer of zeste homolog 2 (165-174); Lysine N-methyltransferase 6 (165-174).
Histone-lysine N-methyltransferase EZH2 (291-299)
Histone-lysine N-methyltransferase EZH2 (291-299) is a bioactive peptide of Histone-lysine N-methyltransferase EZH2. Compared to EZH1-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Alternative Names: ENX-1 (291-299); Enhancer of zeste homolog 2 (291-299); Lysine N-methyltransferase 6 (291-299).
Histone-lysine N-methyltransferase EZH2 (735-743)
Histone-lysine N-methyltransferase EZH2 (735-743) is a bioactive peptide of Histone-lysine N-methyltransferase EZH2. Compared to EZH1-containing complexes, it is more abundant in embryonic stem cells and plays a major role in forming H3K27me3, which is required for embryonic stem cell identity and proper differentiation. Alternative Names: ENX-1 (735-743); Enhancer of zeste homolog 2 (735-743); Lysine N-methyltransferase 6 (735-743).
A cell-permeable compound that is shown (at 1uM concentrations) to inhibit EZH2-mediated trimethylation of K27 on histone H3 and induces the expression of cell-cycle regulatory genes, p21 and p27, as well as the cell death regulator, FBXO32, in OCI-AML3 and HL-60 cells, whereby treatment with inhibitor increases p16 levels in the former, but not the latter of the two cultures. At concentrations between 200nM and 2000nM, this compound is found to dose-dependently deplete the expression of polycomb group proteins EZH2, SUZ12, and EED in cultured and primary AML cell extracts. At concentrations up to ≥ 1000nM, DZNep dose-dependently increases the percentage of apoptotic cells up to > ~ 38%, with greater potency against OCI-AML3 than HL-60 cultures and inhibits colony growth up to > ~ 85% for both cell lines. In OCI-AML3 cultures, 1000nM of treatment demonstrates a significant increase in the accumulation of cells in the G0/G1 phase (58.5%) with a concomitant decrease in the number of c Group: Biochemicals. Grades: Highly Purified. CAS No. 102052-95-9. Pack Sizes: 2mg. Molecular Formula: C??H??N?O?; HCl; H?O. US Biological Life Sciences.
Worldwide
Histone Modification Compound Library
A unique collection of 362 histone modification related compounds for high throughput screening (HTS) and high content screening (HCS); - Detailed compound information with structure, target, activity, IC50 value, and biological activity description; - Structurally diverse, medicinally active, and cell permeable; - NMR and HPLC validated to ensure high purity and quality. Uses: Scientific use. Product Category: L3500. Categories: Histone Modification Compounds Libraries.
Histrelin acetate
Histrelin acetate, a GnRH analogue, is a GnRH Receptor agonist. Histrelin acetate increases serum luteinising hormone (LH), follicle stimulating hormone (FSH) and testosterone levels. Histrelin acetate can be used in the research of prostate cancer, endometriosis[1][2][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 220810-26-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P0056A.
His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt
His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt. Alternative Names: L-Histidyl-L-Tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-N-ethyl-L-prolinamide; H-His-Trp-Ser-Tyr-D-Leu-Leu-Arg-Pro-NHEt; L-histidyl-L-tryptophyl-L-seryl-L-tyrosyl-D-leucyl-L-leucyl-L-arginyl-L-proline ethylamide. Grades: ≥95%. CAS No. 1642799-35-6. Molecular formula: C54H79N15O10. Mole weight: 1098.32.
His-Val-OH
His-Val-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 76019-15-3. Pack Sizes: 100mg, 250mg. US Biological Life Sciences.
Worldwide
Hitachimycin
Hitachimycin is a macrolide antibiotic produced by Streptomyces No. KG-2245. It can inhibit tumor cell growth and antiprotozoal effects. Alternative Names: Stubomycin. Grades: 95%. CAS No. 77642-19-4. Molecular formula: C29H35NO5. Mole weight: 477.59.
HI TOPK 032. Group: Biochemicals. Grades: Purified. CAS No. 487020-03-1. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
HIV-1 gag Protein p24 (194-210)
HIV-1 gag Protein p24 (194-210). Alternative Names: H-Ala-Asn-Pro-Asp-Cys-Lys-Thr-Ile-Leu-Lys-Ala-Leu-Gly-Pro-Ala-Ala-Thr-OH; L-alanyl-L-asparagyl-L-prolyl-L-alpha-aspartyl-L-cysteinyl-L-lysyl-L-threonyl-L-isoleucyl-L-leucyl-L-lysyl-L-alanyl-L-leucyl-glycyl-L-prolyl-L-alanyl-L-alanyl-L-threonine; L-Threonine, L-alanyl-L-asparaginyl-L-prolyl-L-α-aspartyl-L-cysteinyl-L-lysyl-L-threonyl-L-isoleucyl-L-leucyl-L-lysyl-L-alanyl-L-leucylglycyl-L-prolyl-L-alanyl-L-alanyl-. Grades: ≥95%. CAS No. 141281-67-6. Molecular formula: C73H126N20O23S. Mole weight: 1683.99.
HIV-1 Protease, Recombinant
HIV-1 protease is a retroviral aspartyl protease (retropepsin) that is essential for the life-cycle of HIV. HIV protease cleaves newly synthesized viral polyproteins at the appropriate places into functional protein products as mature protein components of an infectious HIV virion. The mutation of HIV protease's active site or inhibition of its activity disrupts HIVs ability to replicate and infect additional cells. Group: Enzymes. Synonyms: HIV-1 retropepsin; HIV-1 Protease (PR); cd05482. Enzyme Commission Number: EC 3.4.23.-. Purity: > 90%. Mole weight: 38.4 kDa (1-99 aa + N-terminal GST and C-terminal Poly-his tags). It runs at ~31 kDa during SEC and SDS-PAGE analyses. Activity: > 1mU/mg. Stability: Stable for at least 6 months as supplied. It can be further diluted to 0.5-1 mg/ml with 50 mM Sodium acetate, 100 mM NaCl, 5 mM DTT, 5 mM EDTA, pH 5.0 containing 10% glycerol, and stored at -80°C in aliquots. Do not keep the enzyme at 4°C or -20°C for extended time. Avoid repeated freezing and thawing cycles. Storage: Store at -80°C. Form: Liquid. Source: E. coli. HIV-1 retropepsin; HIV-1 Protease (PR); cd05482; HIV1 protease. Cat No: NATE-1662.
HIV-1 retropepsin
Present in human immunodeficiency virus type 1. Contributes to the maturation of the viral particle, and is a target of antiviral drugs. Active enzyme is a dimer of identical 11-kDa subunits. Similar enzymes occur in other retroviruses. Type example of peptidase family A2. Group: Enzymes. Synonyms: human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease. Enzyme Commission Number: EC 3.4.23.16. CAS No. 144114-21-6. HIV Protease. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4253; HIV-1 retropepsin; EC 3.4.23.16; 144114-21-6; human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease. Cat No: EXWM-4253.
HIV-1 Rev 34-50
HIV-1 Rev (34-50) is a 17-aa cell-penetrating peptide derived from HIV-1 Rev protein residue 34-50. It is an RNA-binding peptide that has been used to deliver macromolecules into cells. Alternative Names: H-Thr-Arg-Gln-Ala-Arg-Arg-Asn-Arg-Arg-Arg-Arg-Trp-Arg-Glu-Arg-Gln-Arg-OH; HIV-1 Rev Protein (34-50); L-Arginine, L-threonyl-L-arginyl-L-glutaminyl-L-alanyl-L-arginyl-L-arginyl-L-asparaginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-α-glutamyl-L-arginyl-L-glutaminyl-; Revprotein (Human immunodeficiency virus 1 fragment); L-threonyl-L-arginyl-L-glutaminyl-L-alanyl-L-arginyl-L-arginyl-L-asparagyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-alpha-glutamyl-L-arginyl-L-glutaminyl-L-arginine; Rev34-50; HIV-1 Rev (34-50). Grades: ≥95%. CAS No. 141237-50-5. Molecular formula: C97H173N51O24. Mole weight: 2437.74.
HIV-1 TAT (48-60)
HIV-1 TAT (48-60) is a cell-penetrating peptide generated from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way. Alternative Names: H-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Gln-OH; glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-prolyl-L-prolyl-L-glutamine. Grades: ≥95%. Molecular formula: C70H131N35O16. Mole weight: 1719.04.
HIV-1 TAT (48-60)
HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way. Uses: Scientific research. Category: Signaling pathways. CAS No. 220408-24-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1491.
HIV-1-TAT(48-60)
HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way. Alternative Names: HIV-1 TAT (48-60)|CS-0044441. Grades: 99.47%. CAS No. 220408-24-2. Molecular formula: C70H131N35O16. Mole weight: 1719.00.
HIV-1-TAT(48-60) TFA
HIV-1-TAT(48-60) TFA.
HIV-1 Tat Protein (47-57)
HIV-1 Tat Protein (47-57). Uses: For analytical and research use. CAS No. 191936-91-1. Mole weight: 1559.83. Catalog: AP191936911.
HIV-1 TAT protein (47-57) TFA
HIV-1 TAT protein (47-57) TFA.
HIV-1 TAT Protein Peptide
It is a cell-permeable peptide (CPP) derived from the HIV-1 tat protein transduction domain (PTD), which has been shown to promote the entry of nucleic acids into several cell types. Alternative Names: HIV-1 Tat Protein (47-57); H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH; TAT (47-57); L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginine. Grades: 98%. CAS No. 191936-91-1. Molecular formula: C64H118N32O14. Mole weight: 1559.83.
HIV-2 Peptide
HIV-2 Peptide. Alternative Names: HIV-2 env Protein gp41 (86-104); H-Lys-Asp-Gln-Ala-Gln-Leu-Asn-Ser-Trp-Gly-Cys-Ala-Phe-Arg-Gln-Val-Cys-His-Thr-OH (Disulfide bridge: Cys11-Cys17). Grades: ≥95%. CAS No. 172486-63-4. Molecular formula: C93H140N30O28S2. Mole weight: 2190.45.
HIV-2 Protease, Recombinant
HIV-2 Protease, an aspartyl protease (retropepsin), is essential for the life-cycle of HIV-2 sub-type virus. It is expressed in the infected cells as a part of Gag-Pol polyprotein from which it is auto-catalytically released after formation of an immature viral particle. The enzyme subsequently cleaves the other parts of viral polyproteins resulting in the maturation of the virus. In HIV-infected patients, the enzyme is subjected to intensive mutagenesis and mutants resistant to applied medicines are produced as a result of the selection pressure. The mutation of HIV protease's active site or inhibition of its activity disrupts HIVs ability to replicate and infect additional ce.epsin; HIV-2 Protease (PR2); cd05482. Enzyme Commission Number: EC 3.4.23.-. Purity: > 85%. Mole weight: 38.3 kDa (1-99 aa + N-terminal GST and C-terminal Poly-his tags). It runs at ~31.5 kDa during SEC and SDS-PAGE analyses. Stability: Stable for at least 6 months as supplied. It can be further diluted to 0.5-1 mg/ml with 50 mM Sodium acetate, 100 mM NaCl, 5 mM DTT, 5 mM EDTA, pH 5.0 containing 10% glycerol, and stored at -80°C in aliquots. Do not keep the enzyme at 4°C or -20°C for extended time. Avoid repeated freezing and thawing cycles. Storage: Store at -80°C. Form: Liquid. Source: E. coli. HIV-2 retropepsin; HIV-2 Protease (PR2); cd05482; HIV2 protease. Cat No: NATE-1661.
HIV-2 retropepsin
In peptidase family A2. Responsible for the post-translational processing of the human immunodeficiency virus polyprotein. Group: Enzymes. Enzyme Commission Number: EC 3.4.23.47. CAS No. 144114-21-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4284; HIV-2 retropepsin; EC 3.4.23.47; 144114-21-6. Cat No: EXWM-4284.
H-Iva-Ome HCl
H-Iva-Ome HCl. Alternative Names: (S)-Methyl 2-amino-2-methylbutanoate hydrochloride; (S)-2-amino-2-methylbutyric acid methyl ester hydrochloride; H Iva Ome HCl. Grades: 95%. CAS No. 92760-72-0. Molecular formula: C6H14ClNO2. Mole weight: 167.63.
Hivernal® Neo
Hivernal® Neo. CAS No. 300371-33-9. Kosher: Y. VIGON Item # 508452. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers.
America & Internationally
HIV gag peptide 197-205
HIV gag peptide 197-205 is an H-2Kd-restricted epitope consisting of amino acids 197-205 derived from the p24 portion of HIV-1 gag protein. Alternative Names: H-Ala-Met-Gln-Met-Leu-Lys-Glu-Thr-Ile-OH; L-alanyl-L-methionyl-L-glutaminyl-L-methionyl-L-leucyl-L-lysyl-L-alpha-glutamyl-L-threonyl-L-isoleucine. Grades: ≥95%. CAS No. 214978-47-9. Molecular formula: C45H81N11O14S2. Mole weight: 1064.32.
HIV-IN petide
Arg-Val-Leu-(R)-Phe-Glu-Ala-Nle-NH2 contains a reduced peptide bond and is a competitive inhibitor of the HIV-1 protease with a Ki of 50 nM. Alternative Names: 167875-35-6;HIV-IN petide;H-Arg-Val-Leu-psi(CH2NH)Phe-Glu-Ala-Nle-NH2;(4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentyl]amino]-3-phenylpropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid;Arg-Val-Leu-(R)-Phe-Glu-Ala-Nle-NH2;107475-09-2;N-[(2r)-2-({n~5~-[amino(Iminio)methyl]-L-Ornithyl-L-Valyl}amino)-4-Methylpentyl]-L-Phenylalanyl-L-Alpha-Glutamyl-L-Alanyl-L-Norleucinamide;2aoe;0Q4;Peptide Inhibitor CA/p2;N-1270;R-V-L-r-F-E-A-Nle;BDBM13935;HY-P4543;MFCD00237446;H-Arg-Val-Leu-r-Phe-Glu-Ala-Nle-NH2;DA-53842;CS-0655006;(4S)-4-[(2S)-2-{[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-methylbutanamido]-4-methylpentyl]amino}-3-phenylpropanamido]-4-{[(1S)-1-{[(1S)-1-carbamoylpentyl]carbamoyl}ethyl]carbamoyl}butanoic acid. Grades: ≥95%. CAS No. 167875-35-6. Molecular formula: C40H69N11O8. Mole weight: 832.04.
HIV p17 Gag 77-85
HIV p17 Gag 77-85 is used in the research of anti-HIV. Alternative Names: HIV-1 gag Protein p17 (76-84); H-Ser-Leu-Tyr-Asn-Thr-Val-Ala-Thr-Leu-OH; L-seryl-L-leucyl-L-tyrosyl-L-asparagyl-L-threonyl-L-valyl-L-alanyl-L-threonyl-L-leucine; HIV P17 GAG (77-85). Grades: ≥95%. CAS No. 147468-65-3. Molecular formula: C44H72N10O15. Mole weight: 981.10.
HIV Protease Mutant, Recombinant
HIV-1 protease is a retroviral aspartyl protease (retropepsin) that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins at the appropriate places to create the mature protein components of an infectious HIV virion. Without effective HIV protease, HIV virions remain uninfectious. Thus, mutation of HIV protease's active site or inhibition of its activity disrupts HIVs ability to replicate and infect additional cells, making HIV protease inhibition the subject of considerable pharmaceutical research. Group: Enzymes. Synonyms: human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease; HIV-1 retropepsin; HIV Protease Mutant; EC 3.4.23.16. Enzyme Commission Number: EC 3.4.23.16. CAS No. 144114-21-6. HIV Protease. Mole weight: mol wt ~10.8 kDa. Storage: -70°C. Form: Supplied as a solution in 0.5M Sodium Acetate, pH 4.7with 50mM Tris-HCL, 1M NaCL, 1mM EDTA, 5mM DTT and 15% glycerol. Source: E. coli. human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease; HIV-1 retropepsin; HIV Protease Mutant; EC 3.4.23.16. Pack: 100 unit vial containing > 100ug protein. Cat No: NATE-0344.
HIV Protease Substrate VI
HIV Protease Substrate VI is a sensitive chromogenic substrate for both HIV-1 and HIV-2 proteases. Alternative Names: H-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2; L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide; L-Norleucinamide, L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-α-glutamyl-L-alanyl-. Grades: ≥95%. CAS No. 130877-92-8. Molecular formula: C40H66N12O11. Mole weight: 891.04.
HJ445A
HJ445A is a potent MYOF inhibitor and binds to the MYOF-C2D domain with a KD of 0.17 μM. HJ445A potently repressed the proliferation of gastric cancer cells with IC50 values of 0.16 and 0.14 μM in MGC803 and MKN45, respectively. HJ445A demonstrates superior antitumor efficacy in vivo and can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032441-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163084.
HJB97
HJB97 is a high-affinity BET inhibitor with Ki values of 0.9 nM (BRD2 BD1), 0.27 nM (BRD2 BD2), 0.18 nM (BRD3 BD1), 0.21 nM (BRD3 BD2), 0.5 nM (BRD4 BD1), and 1.0 nM (BRD4 BD2)[1]. HJB97 can serve as a ligand for target protein (Ligands for Target Protein for PROTAC) for the development of PROTAC BET degraders with antitumor activity[1]. HJB97 can be used for the synthesis of BETd-260 (HY-101519). Uses: Scientific research. Category: Signaling pathways. CAS No. 2093391-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112429.
HJC0152
HJC0152 is a signal transducers and activators of transcription 3 (STAT3) inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 1420290-99-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100602.
HJC 0350. Group: Biochemicals. Grades: Purified. CAS No. 885434-70-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
HK-2-IN-1
HK-2-IN-1 is a Hexokinase 2 (HK-2) inhibitor. HK-2-IN-1 exhibits a non-activating effect on human recombinant HK-2 enzyme. HK-2-IN-1 has anti-tumor activity, affecting immune cells in the tumor microenvironment. HK-2-IN-1 has immunomodulatory effects and is potentially useful in the study of cancers such as colon cancer, liver cancer, and breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3114833-48-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175035.
HKB99
HKB99 is an allosteric inhibitor of phosphoglycerate mutase 1 (PGAM1). HKB99 induces apoptosis. HKB99 inhibits the formation of invasive pseudopodia and inhibits migration. HKB99 increases the oxidative stress, activates JNK/c-Jun and suppresses AKT and ERK. HKB99 can be used for the research of non-small-cell lung cancer (NSCLC)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414908-90-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148510.