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Product
H-Leu-His-OH H-Leu-His-OH. Synonyms: Leu-His; Leucyl-Histidine; L-leucyl-L-histidine; L-Leu-L-His. CAS No. 38062-72-5. Molecular formula: C12H20N4O3. Mole weight: 268.31. BOC Sciences 10
H-Leu-Ile-OH H-Leu-Ile-OH. Synonyms: Leu-Ile; L-leucyl-L-isoleucine; Leucyl-Isoleucine; L-Isoleucine, L-leucyl-; N-leucyl-isoleucine. Grade: >99%. CAS No. 36077-41-5. Molecular formula: C12H24N2O3. Mole weight: 244.33. BOC Sciences 10
H-LEU-LEU-ALA-OH H-LEU-LEU-ALA-OH. Synonyms: Leu-Leu-Ala; leucyl-leucyl-alanine; L-leucyl-L-leucyl-L-alanine. Grade: 95%. CAS No. 20274-80-0. Molecular formula: C15H29N3O4. Mole weight: 315.41. BOC Sciences 10
H-Leu-OBzl.TOS H-Leu-OBzl.TOS. CAS No: 1738-77-8 Sarchem Laboratories
Sarchem Laboratories New Jersey NJ
H-Leu-ol-2-chlorotrityl resin 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Leu-ol-Trt(2-Cl)-Resin; H-Leu-ol-Barlos Resin; L-Leucinol 2-chlorotrityl resin. BOC Sciences 10
H-Leu-Phe-OMe TFA H-Leu-Phe-OMe TFA. Synonyms: (S)-Methyl 2-((S)-2-amino-4-methylpentanamido)-3-phenylpropanoate 2,2,2-trifluoroacetate; L-Phenylalanine, N-L-leucyl-, Methyl ester, Mono(trifluoroacetate); H Leu Phe OMe TFA. CAS No. 90072-18-7. Molecular formula: C18H25F3N2O5. Mole weight: 406.40. BOC Sciences 10
H-LEU-PRO-OH HCL H-LEU-PRO-OH is a substrate for skin fibroblast prolidase. Synonyms: L-Leucyl-L-proline hydrochloride; (S)-1-((S)-2-Amino-4-methylpentanoyl)pyrrolidine-2-carboxylic acid hydrochloride. Grade: >99%. CAS No. 87178-63-0. Molecular formula: C11H21ClN2O3. Mole weight: 264.75. BOC Sciences 10
H-Leu-Pro-Pro-OH H-Leu-Pro-Pro-OH, the proline-rich tripeptide, has ACE-inhibiting activity as IPP and VPP, with an IC50 of 9.6 μM. Synonyms: H-LPP-OH; L-leucyl-L-prolyl-L-proline; 1-(1-L-Leucyl-L-prolyl)-L-proline; leucyl-prolyl-proline. Grade: 95%. CAS No. 121305-26-8. Molecular formula: C16H27N3O4. Mole weight: 325.41. BOC Sciences
H-Leu-Ser-p-nitro-Phe-Nle-Ala-Leu-OMe trifluoroacetate salt H-Leu-Ser-p-nitro-Phe-Nle-Ala-Leu-OMe trifluoroacetate salt. Synonyms: LSF(NO2)-Nle-AL-Methyl Ester Trifluoroacetate. CAS No. 99764-63-3. Molecular formula: C36H56F3N7O12. Mole weight: 835.86. BOC Sciences 10
H-Leu-Trp-Met-Arg-OH H-Leu-Trp-Met-Arg-OH. Synonyms: L-Arginine, L-leucyl-L-tryptophyl-L-methionyl-. CAS No. 67368-23-4. Molecular formula: C28H44N8O5S. Mole weight: 604.77. BOC Sciences 10
H-Leu-Trp-OH H-Leu-Trp-OH, a natural product found in Trypanosoma brucei and Aeromonas veronii, is an ACE-inhibitory dipeptide with an IC50 of 6.6 μM. It is a substrate for aminopeptidase W (Km = 0.57 mM; kcat = 6770 min-1). Synonyms: H-LW-OH; L-leucyl-L-tryptophan; L-Leu-L-Trp-OH; (S)-2-((S)-2-Amino-4-methyl-pentanoylamino)-3-(1H-indol-3-yl)-propionic acid. Grade: ≥95%. CAS No. 5156-22-9. Molecular formula: C17H23N3O3. Mole weight: 317.38. BOC Sciences 10
hLF1-11 hLF1-11 is a synthetic peptide with potential antibacterial activity. Molecular formula: C56H95N25O14S1. Mole weight: 1374.6. BOC Sciences 10
HLF1-11 HLF1-11, a human lactoferrin-derived peptide, is a broad spectrum antimicrobial agent. HLF1-11 inhibits human MPO activity. HLF1-11 also directs GM-CSF-driven monocyte differentiation toward macrophages, and enhances immune responses[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 183623-03-2. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-106228. MedChemExpress MCE
H-L-Hgn(Trt)-OH H-L-Hgn(Trt)-OH. BOC Sciences 10
HLI 373 HLI 373 is an inhibitor of Hdm2 ubiquitin ligase (E3) that blocks Hdm2-mediated ubiquitylation and proteasomal degradation of p53 and activates p53-dependent transcription. HLI 373 has a therapeutic effect in several tumor cell lines that express wild-type p53 such as LOX-IMVI, A549, HT1080 and U2OS. Synonyms: HLI373; HLI-373; HLI 373; NSC-373989; NSC 373989; NSC373989. 5-[[3-Dimethylamino)propyl]amino]-3,10-dimethylpyrimido[4,5-b]quinoline-2,4(3H,10H)-dione dihydrochloride. Grade: ≥99% by HPLC. CAS No. 502137-98-6. Molecular formula: C18H23N5O2.2HCl. Mole weight: 414.33. BOC Sciences 8
HLI 373 HLI 373. Group: Biochemicals. Grades: Purified. CAS No. 502137-98-6. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 11
Worldwide
HLI373 dihydrochloride HLI373 dihydrochloride is an efficacious Hdm2 inhibitor. HLI373 dihydrochloride inhibits the ubiquitin ligase activity of Hdm2. HLI373 dihydrochloride is effective in inducing apoptosis of several tumor cells that are sensitive to DNA-damaging agents[1]. Antimalarial activity[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1782531-99-0. Pack Sizes: 5 mg; 10 mg. Product ID: HY-108640A. MedChemExpress MCE
HLM006474 HLM006474 is an E2F transcription factor inhibitor that suppresses binding of DNA. It can promote cell differentiation of human pluripotent stem cells (hPSCs). Synonyms: HLM-006474; 7-[(4-ethoxy-3-methylphenyl)-(pyridin-2-ylamino)methyl]-2-methylquinolin-8-ol. Grade: >98%. CAS No. 353519-63-8. Molecular formula: C25H25N3O2. Mole weight: 399.48. BOC Sciences 8
HLM006474 HLM006474 is a pan E2F inhibitor, which inhibits E2F4 DNA-binding with an IC50 of 29.8 μM in A375 cells. Uses: Scientific research. Category: Signaling pathways. CAS No. 353519-63-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-16667. MedChemExpress MCE
HLM 006474 HLM 006474. Group: Biochemicals. Grades: Purified. CAS No. 353519-63-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 11
Worldwide
HLP6 HLP6 is an antibacterial peptide isolated from Homo sapiens. Synonyms: Phe-Gln-Trp-Gln-Arg-Asn-Pro-Arg-Lys-Val-Arg. BOC Sciences 10
H-L-Pen-OH HCl H2O H-L-Pen-OH HCl H2O. Synonyms: H L Pen OH HCl H2O. BOC Sciences 10
H-L-Phe(2-trifluoromethyl)-OH H-L-Phe(2-trifluoromethyl)-OH. Synonyms: L-Phe(2-CF3)-OHo-Trifluoromethyl-L-phenylalanine; (S)-2-Amino-3-(2-trifluoromethyl-phenyl)propionic acid. Grade: ≥ 99% (HPLC). CAS No. 119009-47-1. Molecular formula: C10H10F3NO2. Mole weight: 233.19. BOC Sciences 10
H-L-Phe(2-trifluoromethyl)-OH H-L-Phe(2-trifluoromethyl)-OH. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 1g, 5g, 25g. US Biological Life Sciences. USBiological 11
Worldwide
H-L-Phe-Oall HCl H-L-Phe-Oall HCl. Synonyms: 96039-19-9; (S)-Allyl 2-amino-3-phenylpropanoate hydroChloride; H-L-Phe-Oall HCl; MFCD01074684. Grade: ≥ 99% (HPLC). Molecular formula: C12H15NO2·HCl. Mole weight: 241.72. BOC Sciences 10
H-L-Tyr-ol HCl H-L-Tyr-ol HCl. Synonyms: (S)-4-(2-Amino-3-hydroxypropyl)phenol hydrochloride; L-TYROSINOL; L-Tyrosinol hydrochloride. Grade: ≥ 95%. CAS No. 87745-27-5. Molecular formula: C9H13NO2·HCl. Mole weight: 203.70. BOC Sciences 10
HLX-22 HLX-22 is a humanized monoclonal antibody targeting HER2. HLX-22 induces apoptosis in HER2-overexpressing breast and gastric cancer cells combined with Trastuzumab (HY-P9907). HLX-22 has potent antitumor activity against advanced solid tumors[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AC101. CAS No. 2851060-90-5. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P991588. MedChemExpress MCE
HLY78 HLY78 is an activator of the Wnt/β-catenin pathway. It targets the DIX domain of Axin and potentiates the Axin-LRP6 association, thus promoting LRP6 phosphorylation and Wnt signaling transduction. In zebrafish embryos, HLY78 was shown to increase the expression of the conserved hematopoietic stem cell (HSC) markers, runx1 and cmyb. Synonyms: 4-Ethyl-5-methyl-5,6-dihydro-[1,3]dioxolo[4,5-j]phenanthridine. Grade: ≥98%. CAS No. 854847-61-3. Molecular formula: C17H17NO2. Mole weight: 267.3. BOC Sciences 8
HLY78 HLY78, a Lycorine (HY-N0288) derivative, is a potent activator of the Wnt/β-catenin signaling pathway. HLY78 targets the DIX domain of Axin and promotes the Axin-LRP6 (lipoprotein receptor-related protein 6) association, thus promoting LRP6 phosphorylation and Wnt signal transduction. HLY78 can be used for subarachnoid hemorrhage (SAH) research[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 854847-61-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-122816. MedChemExpress MCE
H-Lys-2-Chlorotrityl Resin 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. BOC Sciences 10
H-Lys(Abz)-Pro-Pro-pNA H-Lys(Abz)-Pro-Pro-pNA is an internally quenched fluorogenic (FRET) substrate. CAS No. 219138-18-8. Molecular formula: C29H37N7O6. Mole weight: 579.65. BOC Sciences 10
H-Lys-Ala-4MβNA 2 HCl It is a specific fluorogenic substrate for dipeptidyl peptidase II (DPP II). Synonyms: Lys-Ala 4-methoxy-beta-naphthylamide dihydrochloride. Grade: 95%. CAS No. 118357-26-9. Molecular formula: C20H30Cl2N4O3. Mole weight: 445.38. BOC Sciences 10
H-Lys-Ala-AMC H-Lys-Ala-AMC. Synonyms: Lysyl-alaninamide 4-methylcoumarin; 7-Lys-ala-4-mca; 7-Lysylalanyl-4-methylcoumarinamide; 4-Methyl-7-[(L-Lys-L-Ala-)amino]coumarin. Grade: 95%. CAS No. 94149-28-7. Molecular formula: C19H26N4O4. Mole weight: 374.43. BOC Sciences 10
H-Lys-Ala-OH H-Lys-Ala-OH. Synonyms: L-lysyl-L-alanine; LYS-ALA; lysyl-alanine; KA dipeptide; Lysine Alanine dipeptide; (S)-2-((S)-2,6-Diamino-hexanoylamino)-propionic acid. CAS No. 17043-71-9. Molecular formula: C9H19N3O3. Mole weight: 217.27. BOC Sciences 10
H-Lys-Ala-pNA 2HCl H-Lys-Ala-pNA 2HCl, a chromogenic substrate for dipeptidyl aminopeptidase II (DPPII), is cleaved from Aspergillus fumigatus by dipeptidyl peptidase V (DPP V). Synonyms: KA-pNA dihydrochloride; L-Lysyl-N-(4-nitrophenyl)-L-alaninamide dihydrochloride; L-Alaninamide, L-lysyl-N-(4-nitrophenyl)-, hydrochloride (1:2). Grade: ≥95%. CAS No. 390366-87-7. Molecular formula: C15H23N5O4.2HCl. Mole weight: 410.30. BOC Sciences 10
H-Lys-AMC H-Lys-AMC is a substrate for aminopeptidase b. Synonyms: L-Lysine 7-amido-4-methylcoumarin. CAS No. 92605-76-0. Molecular formula: C16H21N3O3. Mole weight: 303.36. BOC Sciences 10
H-Lys-Arg-OH H-Lys-Arg-OH. Synonyms: Lys-Arg; L-lysyl-L-arginine; Lysyl-Arginine; KR dipeptide; Lysine Arginine dipeptide. Grade: 95%. CAS No. 29586-66-1. Molecular formula: C12H26N6O3. Mole weight: 302.37. BOC Sciences 10
H-Lys-Asp-OH H-Lys-Asp-OH. Synonyms: Lys-Asp; lysylaspartic acid; L-lysyl-L-aspartic acid; KD dipeptide; L-Lys-L-Asp; Lysine Aspartate dipeptide. CAS No. 20556-18-7. Molecular formula: C10H19N3O5. Mole weight: 261.27. BOC Sciences 10
H-Lys(Boc)-2-Chlorotrityl Resin 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. BOC Sciences 10
H-Lys(Boc)-2-Cl-Trt Resin Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: Nepsilon-Boc-L-lysine-2-chlorotrityl resin. Alfa Chemistry Materials 6
H-Lys(Boc)-OH H-Lys(Boc)-OH. Group: Biochemicals. Grades: Highly Purified. CAS No. 2418-95-3. Pack Sizes: 10g, 25g, 50g, 100g, 250g. Molecular Formula: C11H22N2O4. US Biological Life Sciences. USBiological 11
Worldwide
H-Lys(Boc)-Pro-OH H-Lys(Boc)-Pro-OH. CAS No. 4583-24-8. Molecular formula: C16H29N3O5. Mole weight: 343.42. BOC Sciences 10
H-Lys(Cbz)-OtBu H-Lys(Cbz)-OtBu. Synonyms: N6-[(Phenylmethoxy)carbonyl]-L-lysine 1,1-dimethylethyl ester; N6-Cbz-L-lysine tert-butyl ester; tert-Butyl N6-((benzyloxy)carbonyl)-L-lysinate. CAS No. 63628-63-7. Molecular formula: C18H28N2O4. Mole weight: 336.43. BOC Sciences 10
H-Lys(Dde)-2-Chlorotrityl Resin 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. BOC Sciences 10
H-Lys-Gly-OH. HCl H-Lys-Gly-OH. HCl. Synonyms: (S)-2-(2,6-Diaminohexanamido)acetic acid hydrochloride. CAS No. 40719-58-2. Molecular formula: C8H18ClN3O3. Mole weight: 239.70. BOC Sciences 10
H-Lys(Me)3-OH Chloride Nε,Nε,Nε-Trimethyllysine hydrochloride is a non-protein amino acid active in the biosynthesis of carnitine. Synonyms: Lys(Me)3-OH Chloride; (S)-5-Amino-5-carboxy-N,N,N-trimethylpentan-1-aminium chloride; Nε,Nε,Nε-Trimethyllysine hydrochloride. CAS No. 55528-53-5. Molecular formula: C9H21ClN2O2. Mole weight: 224.73. BOC Sciences 10
H-Lys(Mtt)-2-chlorotrityl resin 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Lys(Mtt)-Trt(2-Cl)-Resin; N-ε-(4-Methyltrityl)-L-lysine 2-chlorotrityl resin. BOC Sciences 10
H-Lys-Phe-Glu-Arg-Gln-OH H-Lys-Phe-Glu-Arg-Gln-OH plays a broad role in targeting protein-enhanced degradation. Synonyms: L-Glutamine, L-lysyl-L-phenylalanyl-L-α-glutamyl-L-arginyl-; H-KFERQ-OH; L-lysyl-L-phenylalanyl-L-alpha-glutamyl-L-arginyl-L-glutamine. Grade: ≥95%. CAS No. 115084-19-0. Molecular formula: C31H50N10O9. Mole weight: 706.79. BOC Sciences 10
H-Lys-Phe-OH. HCl H-Lys-Phe-OH exerts a remarkable ACE- and renin-inhibitory activity. Synonyms: L-Lysyl-L-phenylalanine hydrochloride. CAS No. 4078-58-4. Molecular formula: C15H24ClN3O3. Mole weight: 329.82. BOC Sciences
H-Lys-Pro-OH H-Lys-Pro-OH has the potential as a very promising healing agent in ulcer therapy. Synonyms: Lysylproline; Lys-pro; Lysyl-Proline; L-lysyl-L-proline; KP dipeptide; Lysine Proline dipeptide; L-Proline, L-lysyl-. CAS No. 52766-27-5. Molecular formula: C11H21N3O3. Mole weight: 243.30. BOC Sciences 10
H-Lys(propionyl)-OH H-Lys(propionyl)-OH. Synonyms: (2S)-2-amino-6-(propanoylamino)hexanoic acid. Grade: ≥ 98% (HPLC). CAS No. 1974-17-0. Molecular formula: C9H18N2O5. Mole weight: 202.20. BOC Sciences 10
H-Lys-Trp-Lys-OH H-Lys-Trp-Lys-OH is the positively charged oligopeptide. It displays antibacterial and antiviral activities. Synonyms: Lysyl-tryptophyl-alpha-lysine; N2-(N-L-Lysyl-L-tryptophyl)-L-lysine; L-Lys-L-Trp-L-Lys-OH. Grade: ≥98%. CAS No. 38579-27-0. Molecular formula: C23H36N6O4. Mole weight: 460.57. BOC Sciences 8
H-LYS-TRP-OH H-LYS-TRP-OH. Synonyms: Lys-trp; L-lysyl-L-tryptophan; KW dipeptide; Lysine Tryptophan dipeptide; 2-(6-Amino-2-aminomethyl-hexanoylamino)-3-(1H-indol-3-yl)-propionic acid. CAS No. 50674-18-5. Molecular formula: C17H24N4O3. Mole weight: 332.40. BOC Sciences 10
H-Lys-Tyr-Lys-OH H-Lys-Tyr-Lys-OH can induce nicks at apurinic/apyrimidinic sites in circular DNA. Synonyms: Lysyl-tyrosyl-lysine; L-Lysine, N2-(N-L-lysyl-L-tyrosyl)-; (S)-6-amino-2-((S)-2-((S)-2,6-diaminohexanamido)-3-(4-hydroxyphenyl)propanamido)hexanoic acid. Grade: ≥97%. CAS No. 35193-18-1. Molecular formula: C21H35N5O5. Mole weight: 437.53. BOC Sciences 10
H-LYS-TYR-OH H-LYS-TYR-OH. Synonyms: Lys-Tyr; L-lysyl-L-tyrosine; Lysyltyrosine; KY dipeptide; Lysine Tyrosine dipeptide. CAS No. 35978-98-4. Molecular formula: C15H23N3O4. Mole weight: 309.36. BOC Sciences 10
H-LYS-VAL-OH H-LYS-VAL-OH. Synonyms: Lysylvaline; lys-val; L-lysyl-L-valine; KV dipeptide; Lysine Valine dipeptide. Grade: 95%. CAS No. 20556-11-0. Molecular formula: C11H23N3O3. Mole weight: 245.32. BOC Sciences 10
H-Lys(Z)-OtBu.HCl H-Lys(Z)-OtBu.HCl is a lysine derivative[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5978-22-3. Pack Sizes: 10 mM * 1 mL in DMSO; 25 g; 100 g; 500 g. Product ID: HY-W008029. MedChemExpress MCE
HM03 HM03 is a potent and selective HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) inhibitor. HM03 has anticancer activity[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 500565-15-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-125974. MedChemExpress MCE
HM03 trihydrochloride HM03 trihydrochloride is a potent and selective inhibitor of HSPA5 (Heat shock 70kDa protein 5, also known as Bip, Grp78) with anticancer activity. Synonyms: 4-[(6-Chloro-2-methoxy-9-acridinyl)amino]-2-[(4-methyl-1-piperazinyl)methyl]phenol trihydrochloride; Phenol, 4-[(6-chloro-2-methoxy-9-acridinyl)amino]-2-[(4-methyl-1-piperazinyl)methyl]-, hydrochloride (1:3). Grade: ≥95%. CAS No. 1082532-95-3. Molecular formula: C26H30Cl4N4O2. Mole weight: 572.35. BOC Sciences 8
HM100-Pro Fully programmable. Precise temperature control for heating. Real-time display of speed, temperature and time. Excellent mixing (200-1500rpm). Quick interchange of blocks without tools and automatic block recognition. Compatible with most popular tubes. Block equipped with a lid for heat preservation. Temperature self-calibration. Categories: Labooratory Heating & Cooling Equipment. DLAB Scientific Inc
HM30181 HM30181 is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency (IC(50)=0.63nM) among several MDR1 inhibitors, including cycloporin A, XR9576, and GF120918, and effectively blocked transepithelial transport of paclitaxel in MDCK monolayers (IC(50)=35.4nM). HM30181 is currently under Phase I HM30181 is an oral P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency (IC(50)=0.63nM) among several MDR1 inhibitors, including cycloporin A, XR9576, and GF120918, and effectively blocked transepithelial transport of paclitaxel in MDCK monolayers (IC(50)=35.4nM). HM30181 is currently under Phase I trials. HM30181 was well tolerated after oral administration within the dose range evaluated, with the exception of the repeated administration of 360 mg, for which gastrointestinal disorders were frequently reported. The systemic exposure of HM30181 was relatively low, and dose proportional properties of HM30181 were not observed.trials. HM30181 was well tolerated after oral administration within the dose range evaluated, with the exception of the repeated administration of 360 mg, for which gastrointestinal disorders were frequently reported. The systemic exposure of HM30181 was relatively low, and dose proportional properties of HM30181 were not observed. Synonyms: 4H-1-B… BOC Sciences 8
HM-30181 hydrochloride HM30181 is a P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency among several MDR1 inhibitors with IC50 value of 0.63nM. HM30181 is currently under Phase I trials. Uses: Enhance the oral bioavailability of p-gp substrate drugs. Synonyms: HM-30181 hydrochloride; HM 30181 hydrochloride; HM30181 hydrochloride; N-(2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide hydrochloride. Grade: 98%. CAS No. 849675-88-3. Molecular formula: C38H37ClN6O7. Mole weight: 725.20. BOC Sciences 8
HM-30181 mesylate HM30181 is a P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. HM30181 showed the highest potency among several MDR1 inhibitors with IC50 value of 0.63nM. HM30181 is currently under Phase I trials. Uses: Enhance the oral bioavailability of p-gp substrate drugs. Synonyms: HM-30181 mesylate; HM 30181 mesylate; HM30181 mesylate; N-(2-(2-(4-(2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-4H-chromene-2-carboxamide methanesulfonate; 849675-88-3 (HM30181 HCl salt); 49675-66-7 (HM30181 Free base). Grade: 98%. CAS No. 849675-87-2. Molecular formula: C39H40N6O10S. Mole weight: 784.84. BOC Sciences 8
HM-30181 mesylate monohydrate HM-30181 mesylate monohydrate is a P-glycoprotein (P-gp) inhibitor developed to enhance the oral bioavailability of P-gp substrate drugs. Synonyms: Encequidar mesylate monohydrate; HM-30181 methanesulfonate monohydrate; HM30181 mesylate monohydrate; 4H-1-Benzopyran-2-carboxamide, N-(2-(2-(4-(2-(3,4-dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl)phenyl)-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl)-4-oxo-, methanesulfonate, hydrate (1:1:1); FM0F74; HM 30181A; N-[2-(2-{4-[2-(6,7-dimethoxy-3,4-dihydroisoquinolin-2(1H)-yl)ethyl]phenyl}-2H-tetrazol-5-yl)-4,5-dimethoxyphenyl]-4-oxo-4H-1-benzopyran-2-carboxamide methanesulfonate hydrate (1:1:1); N-[2-[2-[4-[2-(3,4-Dihydro-6,7-dimethoxy-2(1H)-isoquinolinyl)ethyl]phenyl]-2H-tetrazol-5-yl]-4,5-dimethoxyphenyl]-4-oxo-4H-1-benzopyran-2-carboxamide methanesulfonate hydrate (1:1:1); TCA.MSA. Grade: ≥95%. CAS No. 2097125-58-9. Molecular formula: C38H36N6O7.CH4O3S.H2O. Mole weight: 802.85. BOC Sciences 8
HM43239 HM43239 is an orally active and selective inhibitor of FLT3. HM43239 directly inhibits the kinase activity of FLT3 as a reversible Type I inhibitor and effectively modulates downstream p-STAT5 and p-ERK. Synonyms: HM-43239; HM 43239. CAS No. 2569527-64-4. Molecular formula: C29H33ClN6. Mole weight: 501.07. BOC Sciences 8
HM 50316 HM 50316 is a high affinity fatty-acid binding protein 4 (FABP4) inhibitor (Ki < 1 nM) that selectively inhibits FABP4 over FABP3. It inhibits LPS-induced activation of murine macrophages in vitro. HM 50316 may be beneficial for the treatment of atherosclerosis, type 2 diabetes and other inflammatory and metabolic related diseases. Synonyms: HM-50316; HM 50316; HM50316. 2-[[2'-[1-(4-Chlorophenyl)-5-(2-thienyl)-1H-pyrazol-3-yl][1,1'-biphenyl]-3-yl]oxy]-2-methylpropanoic acid. Grade: ≥98% by HPLC. CAS No. 1310361-52-4. Molecular formula: C29H23ClN2O3S. Mole weight: 515.02. BOC Sciences 8
HMBA AM resin HMBA AM resin. Synonyms: 4-Hydroxymethylbenzoyl AM resin; Hydroxymethylbenzoic acid aminomethyl resin. BOC Sciences 10
HMBPP lithium HMBPP lithium is an intermediate in isoprenoid biosynthesis that can be produced by bacteria and protozoa that use the non-mevalonate pathway for isoprenoid biosynthesis. HMBPP lithium is a ligand of the internal domain of BTN3A1 and is an activator for human Vγ9/Vδ2 T cells. HMBPP lithium exhibits phagostimulant property in mosquitos[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (E)-4-Hydroxy-3-methyl-but-2-enyl diphosphate lithium. CAS No. 396726-03-7. Pack Sizes: 1 mg; 5 mg. Product ID: HY-134891. MedChemExpress MCE
HMBR HMBR is an analogue with an additional methyl group on the aromatic ring and is non-fluorescent. HMBR conjugated with Y-FAST emits yellow fluorescence under blue light excitation (Ex= 419 nm; Em= 525-539 nm). HMBR is non-toxic to zebrafish embryos. HMBR has high cell permeability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1287651-36-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1416. MedChemExpress MCE
HMB-Val-Ser-Leu-VE HMB-val-ser-leu-VE is a potent and selective inhibitor of the trypsin-like activity of the 20S proteasome. Synonyms: Ethyl (E,4S)-4-[[(2S)-3-hydroxy-2-[[(2S)-2-[(3-hydroxy-2-methylbenzoyl)amino]-3-methylbutanoyl]amino]propanoyl]amino]-6-methylhept-2-enoate. Grade: ≥98%. CAS No. 862891-04-1. Molecular formula: C26H39N3O7. Mole weight: 505.6. BOC Sciences 8

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