American Chemical Suppliers

A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.

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Product
hSMG-1 inhibitor 11e hSMG-1 inhibitor 11e is a potent and selective hSMG-1 kinase inhibitor with an IC50 of <0.05 nM. hSMG-1 inhibitor 11e shows>900-fold selectivity over mTOR (IC50 of 45 nM), PI3K?/? (IC50s of 61 nM and 92 nM) and CDK1/CDK2 (IC50s of 32 ?M and 7.1 ?M)[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1402452-10-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124760. MedChemExpress MCE
hSMG-1 inhibitor 11j hSMG-1 inhibitor 11j, a pyrimidine derivative, is a potent and selective inhibitor of hSMG-1, with an IC50 of 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3K?/? (IC50=92/60 nM) and CDK1/CDK2 (IC50=32/7.1 ?M). hSMG-1 inhibitor 11j can be used for the research of cancer[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1402452-15-6. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124719. MedChemExpress MCE
Hsp110-STAT3 interaction-IN-1 Row174336 (compound 29) is a potent inhibitor of Hsp110-STAT3 interaction that shows antiproliferative activity against HPAEC cell line, with the IC 50 of 22.67 μM [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 882582-26-5. Pack Sizes: 1 mg. Product ID: HY-Q43097. MedChemExpress MCE
Hsp25 Kinase Inhibitor The Hsp25 Kinase Inhibitor controls the biological activity of Hsp25 KInase. This small molecule/inhibitor is primarily used for Phosphorylation & Dephosphorylation applications. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
HSP27 inhibitor J2 HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition[1][2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: J2. CAS No. 2133499-85-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124653. MedChemExpress MCE
Hsp40 active human recombinant, expressed in E. coli, ?90% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
HSP40, GST tagged human recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
HSP70 Activator II, YM-08 ( (2Z, 5E) -3-ethyl-5- (3-methylbenzo[d]thiazol-2 (3H) -ylidene) -2- (pyridin-2-ylmethylene) thiazolidin-4-one, Heat Shock 70kD Protein Activator II, Hsp70 Chemical Co-Chaperone II, YM-08, YM08, YM8) A cell-permeable, neutrally charged, pyridinium-to-pyridine substituted YM-01 and MKT-077 structural analog that exhibits higher HSP70-binding affinity, but reduced tau degradation-promoting potency in cultures (% degradation of p-tau/total tau = 42/64, 88/89, and 81/80 in HeLaC3 with 30uM YM-08, MKT-077, or YM-01, respectively) and weaker anti-cancer activity (IC50 against MDA-MB-231/MCF10A/MCF7 inuM = 1.4/3.0/2,2/MKT-077, 2.0/3.3/5.2/YM-01, and 8.5/7.8/10.5/YM-08 in 72h). Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 10mg. US Biological Life Sciences. USBiological 4
Worldwide
HSP70, GST tagged human recombinant, expressed in E. coli, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
HSP70, His tagged human recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
HSP70-IN-1 HSP70-IN-1 is a heat shock protein (HSP) inhibitor that interferes with the formation of functional Hsp70-HOP-Hsp90 machinery, and it inhibits the growth of Kasumi-1 cells with an IC50 of 2.3 μM. Synonyms: HSP70-IN-1; HSP70 IN 1; 2-amino-N-[3-[2-(4-methylpiperazin-1-yl)-4-phenylmethoxypyrimidin-5-yl]sulfanylphenyl]acetamide; SCHEMBL1276103. CAS No. 1268273-90-0. Molecular formula: C24H28N6O2S. Mole weight: 464.58. BOC Sciences 10
Hsp90a Active human recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
Hsp90b Active human recombinant, expressed in E. coli, ?80% (SDS-PAGE). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
HSP90?, His tagged human recombinant, expressed in baculovirus infected Sf9 cells, ?70% (SDS-PAGE), buffered aqueous glycerol solution. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
Hsp90-IN-17 hydrochloride Hsp90-IN-17 (Example 5) hydrochloride is an HSP90 inhibitor that can be used in the study of proliferative diseases, such as cancer and neurodegenerative diseases [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1253584-63-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148215A. MedChemExpress MCE
HSP90-IN-22 HSP90-IN-22 (Compound 35) is an Hsp90 inhibitor with antiproliferative properties on cells with IC 50 values of 3.65 μM for MCF7 breast cancer cells and 2.71 μM for SKBr3 breast cancer cells, respectively. Uses: Scientific research. Group: Signaling pathways. CAS No. 442898-75-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-153588. MedChemExpress MCE
Hsp990 HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (HSP90) with potential antineoplastic activity. HSP990 binds to and inhibits the activity of Hsp90, which may result in the proteasomal degradation of oncogenic client proteins, including HER2/ERBB2, and the inhibition of tumor cell proliferation. HSP90, upregulated in a variety of tumor cells, is a molecular chaperone that plays a key role in the conformational maturation, stability and function of oncogenic signaling proteins, such as HER2/ERBB2, AKT, RAF1, BCR-ABL, and mutated p53, as well as many other molecules that are important in cell cycle regulation and/or immune responses. Synonyms: NVP-HSP990; NVP HSP990; NVPHSP990; HSP 990; HSP-990. Grades: >98%. CAS No. 934343-74-5. Molecular formula: C20H18FN5O2. Mole weight: 379.39. BOC Sciences 10
HspA I One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. G↑CGC CGC↓G. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned HspA I gene from Haemophilus species A1. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1124RE. Creative Enzymes
HSPC HSPC. Pack Sizes: 1 g. Product ID: PE-0353. Category: Lipid Excipients. Product Keywords: Pharmaceutical Excipients; Lipid Excipients; HSPC; PE-0353. Purity: ≥99%. Application: Liposome and Micelle Formulations in Market. Product Description: L-α-phosphatidylcholine, hydro genated (Soy). CD Formulation
HS-PEG1500-SH average Mn 1,500. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alfa Chemistry Analytical Products 4
HS-PEG1500-SH Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: HS-PEG-SH, Thiol-PEG-Thiol. Molecular formula: average Mn 1,500. Alfa Chemistry Materials 5
HS-PEG2K-NH2 Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: HS-PEG-NH2. Molecular formula: average Mn 2000. Alfa Chemistry Materials 5
HS-PEG2K-NH2 HCl Salt, average Mn 2,000. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alfa Chemistry Analytical Products 4
HS-PEG3500-NH2 Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: HS-PEG-NH2. Molecular formula: average Mn 3500. Alfa Chemistry Materials 5
HS-PEG3500-NH2 HCl Salt, average Mn 3,500. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alfa Chemistry Analytical Products 4
HS-PEG5K-NH2 HCl Salt, average Mn 5,000. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alfa Chemistry Analytical Products 4
HS-PEG5K-NH2 Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: HS-PEG-NH2. Molecular formula: average Mn 5000. Alfa Chemistry Materials 5
HS-PEG7500-COOH average Mn 7,500. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alfa Chemistry Analytical Products 4
HS-PEG7500-COOH Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: Thiol-PEG-Carboxyl, HS-PEG-COOH, HS-PEG-COOH. Molecular formula: average Mn 7,500. Alfa Chemistry Materials 5
HS-PEG7500-NH2 HCl Salt, average Mn 7,500. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alfa Chemistry Analytical Products 4
HS-PEG7500-NH2 Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Uses: Activated peg derivatives can be used to modify peptides, proteins, or in other bioconjugation applications. pegylated materials have found broad use in drug delivery systems, virology, and immunology, as the incorporation of peg improves pharmacological properties such as increased water solubility, enhanced resistance to degradation (protein hydrolysis), increased circulation half-life, and reduced antigenicity. in addition to pegylation, activated peg derivatives can also be used to form networks for tissue engineering or drug delivery applications, depending on the architecture and reactivity. Group: Poly(ethylene glycol) and poly(ethylene oxide). Alternative Names: HS-PEG-NH2. Molecular formula: average Mn 7,500. Alfa Chemistry Materials 5
HSPyU HSPyU. Group: Biochemicals. Alternative Names: Dipyrrolidino (N-succinimidyloxy) carbenium hexafluorophosphate; N,N,N',N'-Bis(tetramethylene)-O-(N-succinimidyl)uronium hexafluorophosphate; O- (N-Succinimidyl) -N, N, N', N'-bis (tetramethylene) uronium hexafluorophosphate. Grades: Highly Purified. CAS No. 207683-26-9. Pack Sizes: 25g, 50g, 100g, 250g, 500g. Molecular Formula: C13H20F6N3O3P. US Biological Life Sciences. USBiological 7
Worldwide
HSR6071 HSR60716071, a novel pyrazinecarboxamide derivative, exhibits potent inhibition of the IgE-mediated passive cutaneous anaphylaxis (PCA) in rats on oral administration, and that its inhibition of PCA is at least in part due to the depression of allergic histamine release from mast cells. Synonyms: 6-pyrrolidin-1-yl-N-(2H-tetrazol-5-yl)pyrazine-2-carboxamide; 6-(1-pyrrolidinyl)-N-(1H-tetrazol-5-yl)-2-pyrazinecarboxamide; HSR 6071l; HSR-6071. CAS No. 111374-21-1. Molecular formula: C10H12N8O. Mole weight: 260.26. BOC Sciences 9
HSTU HSTU. Group: Biochemicals. Alternative Names: N,N,N',N'-Tetramethyl-O-(N-succinimidyl)uronium hexafluorophosphate; O-(N-Succinimidyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate. Grades: Highly Purified. CAS No. 265651-18-1. Pack Sizes: 50g, 100g, 250g, 500g, 1kg. Molecular Formula: C9H16F6N3O3P. US Biological Life Sciences. USBiological 7
Worldwide
HSV-1-amide UL 26 Open Reading Frame (242-255) HSV-1-amide UL 26 Open Reading Frame (242-255) is a highly characteristic substrate of the herpes simplex virus type 1 protease (HSV-1), which is essential for viral nucleocapsid formation and viral replication. The C-terminal cleavage product of HTYLQASEKFKMWG-amide is detected by fluorescence detector at 280 nm (excitation) and 350 nm (emission), respectively. Synonyms: H-His-Thr-Tyr-Leu-Gln-Ala-Ser-Glu-Lys-Phe-Lys-Met-Trp-Gly-NH2; L-histidyl-L-threonyl-L-tyrosyl-L-leucyl-L-glutaminyl-L-alanyl-L-seryl-L-alpha-glutamyl-L-lysyl-L-phenylalanyl-L-lysyl-L-methionyl-L-tryptophyl-glycinamide; Glycinamide, L-histidyl-L-threonyl-L-tyrosyl-L-leucyl-L-glutaminyl-L-alanyl-L-seryl-L-α-glutamyl-L-lysyl-L-phenylalanyl-L-lysyl-L-methionyl-L-tryptophyl-. Grades: ≥95%. CAS No. 396716-24-8. Molecular formula: C80H117N21O20S. Mole weight: 1724.98. BOC Sciences 6
HSV-gB2 (498-505) HSV-gB2 (498-505) is an immunodominant epitope from herpes simplex virus (HSV) glycoprotein B residues 498-505, acts as H-2Kb-restricted and HSV-1/2-cross-reactive cytotoxic T-lymphocyte (CTL) recognition epitope [1]. Uses: Scientific research. Group: Peptides. CAS No. 149997-91-1. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1862. MedChemExpress MCE
HT1171 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products
HT-2157 HT-2157 (SNAP 37889) is a selective, high-affinity, competitive antagonists of galanin-3 receptor (Gal3). Uses: Scientific research. Group: Signaling pathways. Alternative Names: SNAP 37889. CAS No. 303149-14-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-100717. MedChemExpress MCE
HT-2 toxin HT-2 toxin is a mycotoxin produced by Fusarium sp. Symptoms of poisoning are nausea, vomiting, diarrhea, and leukopenia. The acute toxicity is lower than trichothecene. Uses: This product is used as a reference standard in quantitative analysis of food stuffs. Synonyms: Mycotoxin HT 2; Toxin HT 2. CAS No. 26934-87-2. Molecular formula: C22H32O8. Mole weight: 424.48. BOC Sciences 5
HT-2 Toxin HT-2 Toxin is a trichothecene group mycotoxin. HT-2 Toxin is the 4-hydroxy analogue of T-2 Toxin which has been shown to induce DNA damage and cell death on prolonged administration. Group: Biochemicals. Alternative Names: (3α,4 β,8α)-12,13-Epoxytrichothec-9-ene-3,4,8,15-tetrol 8-(3-Methylbutanoate) 15-Acetate; 12,13-Epoxytrichothec-9-ene-3α,4 β,8α,15-tetro 15-Acetate 8-Isovalerate; 3,4-Dihydroxy-15-acetoxy-8-(3-methylbutyryloxy)-12,13-epoxy-Δ9-trichothecene; Isovaleric Acid 8-Ester with 12,13-epoxytrichothec-9-ene-3α,4 β,8α,15-tetrol 15-Acetate; HT 2; HT 2 Toxin; Mycotoxin HT 2; NSC 278571; Toxin HT 2. Grades: Highly Purified. CAS No. 26934-87-2. Pack Sizes: 1mg. US Biological Life Sciences. USBiological 2
Worldwide
HT-61 HT-61, also known as HY-50A, is a pyrroloquinolone antibiotic potentially for the treatment of staphylococcal infections. HT61 was effective at reducing biofilm viability and was associated with increased expression of cell wall stress and division proteins, confirming its potential as a treatment for S. aureus biofilm infections. HT61 enhances the effect of tobramycin against Pseudomonas aeruginosa in vitro and in vivo. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HT-61; HT61; HT 61; HY-50A; HY 50A; HY50A. Product Category: Others. Appearance: Solid powder. CAS No. 936622-80-9. Molecular formula: C26H24N2O. Mole weight: 380.49. Purity: >98%. IUPACName: 4-methyl-1-phenethyl-8-phenoxy-2,3-dihydro-1H-pyrrolo[3,2-c]quinoline. Canonical SMILES: CC1=NC2=CC=C(OC3=CC=CC=C3)C=C2C4=C1CCN4CCC5=CC=CC=C5. Product ID: ACM936622809. Alfa Chemistry — ISO 9001:2015 Certified. Categories: HQ-6. Alfa Chemistry.
HTBA HTBA(3-Hydroxy-2,4,6-triiodobenzoic acid) for your research needs. Uses: Scientific research. Group: Biochemical assay reagents. CAS No. 53279-72-4. Pack Sizes: 10 mM * 1 mL; 5 g. Product ID: HY-15919. MedChemExpress MCE
HTH-01-015 HTH-01-015 is a potent and selective inhibitor of NUAK1 (IC50 = 100 nM) and does not affect the activity of a panel of 139 other kinases, including additional AMPK family members. The administration of HTH-01-015 to MEFs (mouse embryonic fibroblasts) significantly inhibits migration in a wound-healing assay to a similar extent as NUAK1-knockout. HTH-01-015 also inhibit proliferation of MEFs to the same extent as NUAK1 knockout and U2OS cells to the same extent as NUAK1 shRNA knockdown. HTH-01-015 impaired the invasive potential of U2OS cells in a 3D cell invasion assay to the same extent as NUAK1 knockdown. HTH-01-015 will serve as useful chemical probes to delineate the biological roles of the NUAK kinases. Uses: Designed for use in research and industrial production. Additional or Alternative Names: HTH-01-015; HTH01-015; HTH 01-015; HTH-01015; HTH01015; HTH 01015. Product Category: Inhibitors. Appearance: Solid powder. CAS No. 1613724-42-7. Molecular formula: C26H28N8O. Mole weight: 468.57. Purity: >98%. IUPACName: 4,5,13-trimethyl-2-((1-(piperidin-4-yl)-1H-pyrazol-4-yl)amino)-5,13-dihydro-6H-naphtho[2,3-e]pyrimido[5,4-b][1,4]diazepin-6-one. Canonical SMILES: CC1=C(N(C)C(C2=CC(C=CC=C3)=C3C=C2N4C)=O)C4=NC(NC5=CN(N=C5)C6CCNCC6)=N1. Product ID: ACM1613724427. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry.
HTH-01-015 HTH-01-015 is a selective NUAK1/ARK5 inhibitor (IC50 is 100 nM). HTH-01-015 inhibits NUAK1 with >100-fold higher potency than NUAK2 (IC50 of >10 ?M). Uses: Scientific research. Group: Signaling pathways. CAS No. 1613724-42-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12334. MedChemExpress MCE
HTH-01-015 HTH-01-015 is a potent and selective inhibitor of NUAK1 with IC50 of 100 nM, does not significantly inhibit NUAK2 (IC50 of >10 μM). Synonyms: HTH-01-015; HTH01-015; HTH 01-015; HTH-01015; HTH01015; HTH 01015. Grades: >98%. CAS No. 1613724-42-7. Molecular formula: C26H28N8O. Mole weight: 468.55. BOC Sciences 10
HTH-01-015 ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 2
H-Thr(ac)-oh H-Thr(ac)-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: O-ACETYL-L-THREONINE;H-THR(AC)-OH. CAS No. 17012-42-9. Molecular formula: C6H11NO4. Mole weight: 161.16. Purity: 0.98. IUPACName: (2S,3R)-3-acetyloxy-2-aminobutanoicacid. Canonical SMILES: CC(C(C(=O)O)N)OC(=O)C. Product ID: ACM17012429. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 2
H-Thr(bzl)-oh H-Thr(bzl)-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: (2S,3R)-2-Amino-3-(benzyloxy)butanoic acid, O-BENZYL-L-THREONINE, 4378-10-3, AmbotzHAA5070, SureCN288386, AC1OCV07, CTK1D5559, L-Threonine, O-(phenylmethyl)-, MolPort-008-268-011, ANW-58139, AKOS016003047, AG-C-27075, AM82264, AK-87492, KB-59256, FT-0635251, (2S,3R)-2-amino-3-phenylmethoxybutanoic acid, Butyricacid, 2-amino-3-(benzyloxy)- (6CI,7CI);Butyric acid,2-amino-3-(benzyloxy)-, L- (8CI);(2S,3R)-2-Amino-3-benzyloxybutanoicacid;O-Benzyl-L-threonine;O-Benzylthreonine;H-Thr-Obzl.HCl. Product Category: Heterocyclic Organic Compound. CAS No. 4378-10-3. Molecular formula: C11H15NO3. Mole weight: 209.24. Purity: 0.96. IUPACName: (2S,3R)-2-amino-3-phenylmethoxybutanoic acid. Canonical SMILES: CC(C(C(=O)O)N)OCC1=CC=CC=C1. Product ID: ACM4378103. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
H-Threoninol(Bzl) Synonyms: H-Thr(Bzl)-ol; (2R,3R)-2-Amino-3-(benzyloxy)butan-1-ol. Molecular formula: C11H17NO2. Mole weight: 195.26. BOC Sciences 3
H-Thr-Leu-OH Synonyms: Thr-Leu; threonylleucine; L-threonyl-L-leucine; TL dipeptide; Threonine Leucine dipeptide. CAS No. 50299-12-2. Molecular formula: C10H20N2O4. Mole weight: 232.28. BOC Sciences 6
H-Thr-Pro-Asn-Gln-Arg-Gln-Asn-Val-Cys-OH H-Thr-Pro-Asn-Gln-Arg-Gln-Asn-Val-Cys-OH is a naturally presented epitope of HLA-B7 molecules recognized by CTL RP1 on the cell surface. Synonyms: L-Threonyl-L-prolyl-L-asparaginyl-L-glutaminylarginyl-L-glutaminyl-L-asparaginyl-L-valyl-L-cysteine. Grades: ≥95%. CAS No. 2022956-41-6. Molecular formula: C41H70N16O15S. Mole weight: 1059.17. BOC Sciences 6
H-Thr-Pro-OH HCl Cas No. 281670-51-7. Molecular formula: C9H17ClN2O4. Mole weight: 252.69. BOC Sciences 6
H-Thr(tBu)-2-Cl-Trt Resin Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Group: Amino acid 2-cl-trt resins. Alternative Names: O-t-Butyl-L-threonine-2-chlorotrityl resin. Pack Sizes: 5g, 25g. Alfa Chemistry Materials 3
H-Thr(tBu)-OMe.HCl H-Thr(tBu)-OMe.HCl is a threonine derivative [1]. Uses: Scientific research. Group: Peptides. CAS No. 71989-43-0. Pack Sizes: 10 g; 25 g; 100 g. Product ID: HY-W042013. MedChemExpress MCE
H-Thr(tbu)-pna H-Thr(tbu)-pna. Uses: Designed for use in research and industrial production. Additional or Alternative Names: AC1OLRDW, H-THR -PNA, (2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]-N-(4-nitrophenyl)butanamide, 201807-08-1. Product Category: Heterocyclic Organic Compound. CAS No. 201807-08-1. Molecular formula: C14H21N3O4. Mole weight: 295.33. Purity: 0.96. IUPACName: (2S,3R)-2-amino-3-[(2-methylpropan-2-yl)oxy]-N-(4-nitrophenyl)butanamide. Product ID: ACM201807081. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 4
H-THR-VAL-OH H-THR-VAL-OH. Uses: Designed for use in research and industrial production. Additional or Alternative Names: H-THR-VAL-OH;L-THREONYL-L-VALINE. Product Category: Heterocyclic Organic Compound. CAS No. 99032-17-4. Molecular formula: C9H18N2O4. Mole weight: 218.25. Product ID: ACM99032174. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 3
H-Tic-Ome HCl Synonyms: (2S,4S)-4-Phenylpyrrolidine-2-Carboxylic Acid Hydrochloride; H-Tic-Ome HCl. Grades: 95%. CAS No. 90657-53-7. Molecular formula: C11H13NO2·HCl. Mole weight: 227.7. BOC Sciences 4
HTL-001 HTL-001 is a novel inhibitor of HOX/PBX binding. In mouse models, it inhibited the growth of prostate and breast tumor. Besides, HTL-001 can significantly increase the expression of cFos and DUSP1, which are targets of HXR9. Uses: Anti-prostate and breast tumor. Synonyms: HTL-001; HTL001. BOC Sciences 11
HTL26119 HTL26119 is a glucagon-like peptide-1 receptor (GLP-1R) antagonist. Synonyms: HTL-26119; HTL 26119. Grades: ≥98% by HPLC. Molecular formula: C28H23Cl3N2O5. Mole weight: 573.85. BOC Sciences 10
H-Tle-Ome HCl Synonyms: L-Tert-Leucine Methyl Ester Hydrochloride; (S)-Methyl 2-Amino-3,3-Dimethylbutanoate Hydrochloride; Methyl (2S)-2-Amino-3,3-Dimethylbutanoate Hydrochloride. Grades: 95%. CAS No. 63038-27-7. Molecular formula: C7H15NO2·HCl. Mole weight: 181.7. BOC Sciences 5
HTLV-II Rex-(4-16) It is a cell penetrating peptide. Synonyms: H-Thr-Arg-Arg-Gln-Arg-Thr-Arg-Arg-Ala-Arg-Arg-Asn-Arg-OH; L-threonyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-threonyl-L-arginyl-L-arginyl-L-alanyl-L-arginyl-L-arginyl-L-asparagyl-L-arginine. Grades: ≥95%. Molecular formula: C68H131N39O18. Mole weight: 1783.05. BOC Sciences 4
HTMT dimaleate HTMT dimaleate. Group: Biochemicals. Grades: Purified. CAS No. 195867-54-0. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. USBiological 5
Worldwide
HTMT dimaleate HTMT dimaleate is a histamine H1 and H2 receptor agonist with 4x104 fold activity over histamine in H2-mediated effects in natural suppressor cells. HTMT dimaleate increases intracellular Ca2+ and IP3 in lymphocytes through a binding site except for H1, H2 or H3. Synonyms: 6-[2- (4-Imidazolyl) ethylamino]-N- (4-trifluoromethylphenyl) heptanecarboxamide dimaleate; Histamine trifluoromethyl toluidide. Grades: ≥99% by HPLC. CAS No. 195867-54-0. Molecular formula: C19H25F3N4O.2C4H4O4. Mole weight: 614.57. BOC Sciences 10
HtrA2 peptidase This enzyme is upregulated in mammalian cells in response to stress induced by both heat shock and tunicamycin treatment. It can induce apoptosis in a caspase-independent manner through its peptidase activity and in a caspase-dependent manner by disrupting the interaction between caspase and the inhibitor of apoptosis (IAP). Belongs in peptidase family S1C. Group: Enzymes. Synonyms: high temperature requirement protein A2; HtrA2; Omi stress-regulated endoprotease; serine proteinase OMI; HtrA2 protease; OMI/HtrA2 protease; HtrA2/Omi; Omi/HtrA2. Enzyme Commission Number: EC 3.4.21.108. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4103; HtrA2 peptidase; EC 3.4.21.108; high temperature requirement protein A2; HtrA2; Omi stress-regulated endoprotease; serine proteinase OMI; HtrA2 protease; OMI/HtrA2 protease; HtrA2/Omi; Omi/HtrA2. Cat No: EXWM-4103. Creative Enzymes
H+-transporting two-sector ATPase A multisubunit non-phosphorylated ATPase that is involved in the transport of ions. Large enzymes of mitochondria, chloroplasts and bacteria with a membrane sector (Fo, Vo, Ao) and a cytoplasmic-compartment sector (F1, V1, A1). The F-type enzymes of the inner mitochondrial and thylakoid membranes act as ATP synthases. All of the enzymes included here operate in a rotational mode, where the extramembrane sector (containing 3 α- and 3 β-subunits) is connected via the Δ-subunit to the membrane sector by several smaller subunits. Within this complex, the γ- and ε-subunits, as well as the 9-12 c subunits rotate by consecutive 120° angles and perform...cal conditions, they pump H+ rather than synthesize ATP. Group: Enzymes. Synonyms: ATP synthase; F1-ATPase; FoF1-ATPase; H+-transporting ATPase; mitochondrial ATPase; coupling factors (F0, F1 and CF1); chloroplast ATPase; bacterial Ca2+/Mg2+ ATPase. Enzyme Commission Number: EC 7.1.2.2 (Formerly EC 3.6.3.14). Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4650; H+-transporting two-sector ATPase; EC 3.6.3.14; ATP synthase; F1-ATPase; FoF1-ATPase; H+-transporting ATPase; mitochondrial ATPase; coupling factors (F0, F1 and CF1); chloroplast ATPase; bacterial Ca2+/Mg2+ ATPase. Cat No: EXWM-4650. Creative Enzymes
H-Trisaccharide synthetic. Group: Fluorescence/luminescence spectroscopy. Alfa Chemistry Analytical Products 3
H-Trp(5-Cl)-OH Synonyms: 2-Amino-3-(5-Chloro-1H-Indol-3-Yl)Propanoic Acid. CAS No. 154-07-4. Molecular formula: C11H11ClN2O2. Mole weight: 238.7. BOC Sciences 4
H-Trp(7-Me)-OH Synonyms: 7-methyl-L-tryptophan. Grades: 95%. CAS No. 33468-36-9. Molecular formula: C12H14N2O2. Mole weight: 218.25. BOC Sciences 5
H-Trp-Asn-OH Tryptophanyl-asparagine is a dipeptide composed of Tryptophan and asparagine. Synonyms: Trp-Asn. CAS No. 175027-11-9. Molecular formula: C15H18N4O4. Mole weight: 318.33. BOC Sciences 6
H-Trp-beta-ala-oh H-Trp-beta-ala-oh. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-TRYPTOPHYL-BETA-ALANINE;H-TRP-BETA-ALA-OH;L-TRYPTOPHYL-B-ALANINE. Product Category: Heterocyclic Organic Compound. CAS No. 67607-64-1. Molecular formula: C14H17N3O3. Mole weight: 275.3. Purity: 0.96. IUPACName: H-TRP-β-ALA-OH. Product ID: ACM67607641. Alfa Chemistry — ISO 9001:2015 Certified. Alfa Chemistry. 5

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