A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
H-Phe-Trp-OH (Phenylalanyltryptophan) is an endogenous metabolite. H-Phe-Trp-OH can be used in the research of hepatocellular carcinoma and tic disorders[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Phenylalanyltryptophan; Phe-Trp. CAS No. 24587-41-5. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-W092109.
H-PHE-TRP-OH
H-PHE-TRP-OH. Alternative Names: L-Phe-L-Trp-OH. CAS No. 24587-41-5. Purity: 98%. Product ID: ACM24587415. Molecular formula: C20H21N3O3. Mole weight: 351.40. Alfa Chemistry - ISO 9001:32057 Certified.
H-Phg-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Alternative Names: H-Phg-Trt(2-Cl)-Resin; H-Phg-Barlos Resin; L-Phenylglycine 2-chlorotrityl resin.
H-Phg(4-OH)-Oet
H-Phg(4-OH)-Oet. Alternative Names: (S)-ETHYL 2-AMINO-2-(4-HYDROXYPHENYL)ACETATE. Grades: ≥ 95%. CAS No. 43189-39-5. Molecular formula: C10H13NO3. Mole weight: 195.2.
H-Phg(4-OH)-OH
A carnitine palmitoyltransferase-1 inhibitor. It has been shown to improve whole-body glucose tolerance and insulin sensitivity in high-fat diet-induced obese mouse with insulin resistance. Uses: Enzyme inhibitors. Alternative Names: Oxfenicine; 4-Hydroxy-L-phenylglycine; L-4-Hydroxyphenylglycine; (2S)-2-amino-2-(4-hydroxyphenyl)acetic acid. Grades: ≥98%. CAS No. 32462-30-9. Molecular formula: C8H9NO3. Mole weight: 167.16.
HPI-1 hydrate
HPI-1 hydrate. Group: Biochemicals. Alternative Names: 1,4,5,6,7,8-Hexahydro-4-(3-hydroxyphenyl)-7-(2-methoxyphenyl)-2-methyl-5-oxo-3-quinolinecarboxylic acid 2-methoxyethyl ester hydrate. Grades: Highly Purified. CAS No. 1262770-72-8. Pack Sizes: 10mg, 25mg, 50mg, 100mg, 250mg. Molecular Formula: C27H31NO7. US Biological Life Sciences.
Worldwide
HPK1-IN-3
HPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC50 of 0.25 nM. HPK1-IN-3 has IL-2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2739844-34-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138568.
HPK1-IN-32
HPK1-IN-32 is a potent and selective HPK1 inhibitor with an IC50 of 65 nM. HPK1-IN-32 can be used for the research of HPK1 related disorders or diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2766481-17-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148847.
HPK1-IN-34
HPK1-IN-34 (Compound 143) is a Hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of <100 nM[1]. HPK1-IN-34 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2380300-99-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153362.
HPLC Analysis of Cholesterol-Lowering Drugs (Statins) on Discovery Cyano
HPLC Analysis of Cholesterol-Lowering Drugs (Statins) on Discovery Cyano. Product ID: ACMA00005296. Alfa Chemistry - ISO 9001:32057 Certified.
HPMC
Hydroxypropyl methylcellulose (HPMC) is a semisynthetic, inert, viscoelastic polymer of cellulose. Cellulose is alkali-treated then reacted with propylene oxide and methyl chloride to produce hydroxypropyl methylcellulose. Hydroxypropyl substitution increases water solubility, thermal gelation and film-forming properties. HPMC is non-ionic and displays reversible thermal gelation. HPMC can have a low, medium or high viscosity based on molecular weight and degree of substitution. Applications: Applications of hpmc include its use as a binder, disintegrant and controlled release matrix component of tablets in the pharmaceutical industry; it is also used in vegetarian capsules and solutions for eye medications. used as an ingredient in construction materials such as tile adhesive and self-leveling cement, it imparts water retention, workability, and adhesion characteristics. it is used in the food industry as a thickener/emulsifier/stabilizer in sauces, baked goods and meat substitutes. hpmc can also be used in cosmetics as a viscosity control agent and film former for shampoo, lotion, and makeup. Category: Cellulose series. CAS No. 9004-65-3. Product ID: PIE-0230. Appearance: White powder.
HPMC (Type II,Viscosity:100000mPa.s)
HPMC (Hypromellose; (Hydroxypropyl)methyl cellulose; Celacol HPM 5000) (Type II,Viscosity:100000mPa.s) is a non-ionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs in the hydrated matrix and the polymer relaxation process[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Type II,Viscosity:100000mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:100000mPa.s); Celacol HPM 5000 (Type II,Viscosity:100000mPa.s). CAS No. 9004-65-3. Pack Sizes: 100 g; 500 g; 1 k g. Product ID: HY-A0104I.
HPMC (Type II,Viscosity:3mPa.s)
HPMC (Type II, Viscosity: 3 mPa.s) is a nonionic polymer prepared via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, which includes the diffusion of drugs in the hydrated matrix and the polymer relaxation process[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Type II,Viscosity:3mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:3mPa.s); Celacol HPM 5000 (Type II,Viscosity:3mPa.s). CAS No. 9004-65-3. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-A0104K.
HPMC (Type II,Viscosity:5mPa.s)
HPMC (Hypromellose) (Type II,Viscosity:5mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. HPMC (Type II,Viscosity:5mPa.s) is widely used in agent formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Type II,Viscosity:5mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:5mPa.s); Celacol HPM 5000 (Type II,Viscosity:5mPa.s). CAS No. 9004-65-3. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-A0104J.
HPMC (Type I,Viscosity:30mPa.s)
Hydroxypropylmethylcellulose (Type I,Viscosity:30mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Type I,Viscosity:30mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:30mPa.s); Celacol HPM 5000 (Type I,Viscosity:30mPa.s). CAS No. 9004-65-3. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-A0104A.
HPMC (Type I,Viscosity:4000mPa.s)
HPMC (Hypromellose) (Type I, Viscosity: 4000mPa.s) is a primary sodium alginate and controlled release hydrophilic polymer with an average viscosity of 4000mPa.s. The viscosity of HPMC may change due to concentration, pH, temperature or the presence of metal ions. When the pH is above 10, the viscosity decreases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Type I,Viscosity:4000mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:4000mPa.s); Celacol HPM 5000 (Type I,Viscosity:4000mPa.s). CAS No. 9004-65-3. Pack Sizes: 5 g; 10 g. Product ID: HY-A0104D.
HPMC (Viscosity:11250-21000mPa.s)
HPMC (Viscosity:11250-21000mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Viscosity:11250-21000mPa.s); (Hydroxypropyl)methyl cellulose (Viscosity:11250-21000mPa.s); Celacol HPM 5000 (Viscosity:11250-21000mPa.s). CAS No. 9004-65-3. Pack Sizes: 500 mg; 1 g. Product ID: HY-A0104.
HPN-01
HPN-01 is a potent and selective IKK inhibitor, with pIC50 values of 6.4, 7.0 and <4.8 for IKK-α, IKK-β and IKK-ε, respectively. HPN-01 displays greater 50-fold selectivity over a panel of more than 50 other kinases, including ALK5, CDK-2, EGFR, ErbB2, GSK3β, PLK1, Src, and VEGFR-2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 928655-63-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135366.
HP-NH2
CD Bioparticles provides HP-NH2, Heparins for drug delivery. Group: Heparins.
HPPD-IN-3
HPPD-IN-3 (compound 25) is a potent inhibitor of 4-Hydroxyphenylpyruvate dioxygenase (HPPD), with IC50 of 10 nM, more potency than Mesotrione (HY-12853)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3024245-46-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161308.
HPPE
HPPE (compound 236) is an orally active, potential Bach1 inhibitor. Bach1 is a transcription factor of the cap'n'collar type alkaline region leucine zipper factor family (CNC-bZip) that regulates mitochondrial metabolism and reduces glucose utilization. HPPE can be used for research in psoriasis, multiple sclerosis, and COPD[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bach1-IN-1. CAS No. 1325721-55-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153040.
HPPH
HPPH (Photochlor) is a second generation photosensitizer, which acts as a photodynamic therapy (PDT) agent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Photochlor. CAS No. 149402-51-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13722.
HPPH
HPPH. Pack Sizes: Milligram Quantities: 50 mg. Order Number: I105.
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H-p-Phenyl-D-Phenylalanine
H-p-Phenyl-D-Phenylalanine. Group: Biochemicals. Alternative Names: D-Bip(4,4')-OH; H-p-Phenyl-D-Phe-OH; (R)-2-Amino-3-biphenyl-4-yl-propionic acid. Grades: Highly Purified. CAS No. 170080-13-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences.
Worldwide
H-p-Phenyl-D-Phenylalanine
H-p-Phenyl-D-Phenylalanine. Alternative Names: D-Bip(4,4')-OH; H-p-Phenyl-D-Phe-OH; (R)-2-Amino-3-biphenyl-4-yl-propionic acid. Grades: ≥ 98% (TLC). CAS No. 170080-13-4. Molecular formula: C15H15NO2. Mole weight: 241.29.
H-p-Phenyl-D-Phenylalanine 98+% (TLC)
H-p-Phenyl-D-Phenylalanine 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 10g. US Biological Life Sciences.
Worldwide
H-p-Phenyl-L-Phenylalanine
H-p-Phenyl-L-Phenylalanine. Group: Biochemicals. Alternative Names: L-Bip(4,4')-OH; H-L-Ala(4,4'-biphenyl)-OH; (S)-2-Amino-3-biphenyl-4-yl-propionic acid. Grades: Highly Purified. CAS No. 155760-02-4. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
H-p-Phenyl-L-Phenylalanine
H-p-Phenyl-L-Phenylalanine. Alternative Names: L-Bip(4,4')-OH; H-L-Ala(4,4'-biphenyl)-OH; (S)-2-Amino-3-biphenyl-4-yl-propionic acid. Grades: ≥ 99.0% (HPLC). CAS No. 155760-02-4. Molecular formula: C15H15NO2. Mole weight: 241.29.
H-p-Phenyl-L-Phenylalanine 99+%
H-p-Phenyl-L-Phenylalanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences.
Worldwide
H-Pro-2-Chlorotrityl Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
H-Pro-2-Cl-Trt Resin
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: L-Proline-2-chlorotrityl resin.
H-Pro-AMC
H-Pro-AMC. Alternative Names: (S)-N-(4-Methyl-2-oxo-2H-chromen-7-yl)pyrrolidine-2-carboxamide. CAS No. 96643-94-6. Molecular formula: C15H16N2O3. Mole weight: 272.30.
H-Pro-Arg-AMC. 2 HCl
H-Pro-Arg-AMC is a fluorogenic Plasmodium falciparum dipeptidyl aminopeptidase 1 (DPAP1, cathepsin C) substrate. Alternative Names: H-Pro-Arg-AMC. 2 HCl. Grades: 95%. CAS No. 546103-85-9. Molecular formula: C21H28N6O4. Mole weight: 428.49.
H-Pro-Asn-OH
Prolyl-Asparagine is a dipeptide composed of proline and asparagine. Alternative Names: Pro-Asn; H-Pro-Asn-OH; L-prolyl-L-asparagine. CAS No. 107856-82-6. Molecular formula: C9H15N3O4. Mole weight: 229.23.
H-Pro-Gly-Pro-OH (PGP), a tripeptide produced by the breakdown of extracellular matrix collagen, has specific chemotactic effects on neutrophils in vitro and in vivo. Ac-PGP generated by N-terminal acetylation of PGP can enhance this chemotactic potential. PGP is a physiological substrate for the activity of leukotriene A4 hydrolase aminopeptidase, and a biomarker for chronic obstructive pulmonary disease (COPD). Alternative Names: H-PGP-OH; L-prolyl-glycyl-L-proline; L-Proline, L-prolylglycyl-; prolyl-glycyl-proline. Grades: ≥95% by HPLC. CAS No. 7561-51-5. Molecular formula: C12H19N3O4. Mole weight: 269.30.
H-Pro-Gly-Pro-OH
H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pro-Gly-Pro. CAS No. 7561-51-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4486.
H-Pro-Hyp-OH
H-Pro-Hyp-OH is a collagen peptide composed of proline (Pro) and hydroxyproline (Hyp). H-Pro-Hyp-OH can be used in research on slowing down facial aging[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Prolylhydroxyproline; Pro-Hyp. CAS No. 18684-24-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W337672.
H-Pro-Ile-OH
H-Pro-Ile-OH is a derivative of isoleucine, an α-amino acid that is used in the biosynthesis of proteins. Alternative Names: Pro-ile; Prolylisoleucine; l-prolyl-l-isoleucine; N-L-Prolyl-L-isoleucine; L-Pro-L-Ile-OH. CAS No. 51926-51-3. Molecular formula: C11H20N2O3. Mole weight: 228.29.
H-PRO-LEU-GLY-NHOH HCL
An affinity ligand for the purification of human collagenases. Alternative Names: Pro-Leu-Gly hydroxamate hydrochloride. Grades: 95%. CAS No. 120928-08-7. Molecular formula: C13H25ClN4O4. Mole weight: 336.82.
H-PRO-LEU-OH
H-PRO-LEU-OH. Alternative Names: Pro-leu; L-prolyl-L-leucine; (S)-4-Methyl-2-((S)-pyrrolidine-2-carboxamido)pentanoic acid. CAS No. 52899-07-7. Molecular formula: C11H20N2O3. Mole weight: 228.29.
H-Pro-Met-OH
H-Pro-Met-OH is used as an antihypertensive drug or health care product. Alternative Names: L-Prolyl-L-methionine; Pro-Met; prolylmethionine; PM dipeptide; Proline Methionine dipeptide. Grades: >99%. CAS No. 52899-08-8. Molecular formula: C10H18N2O3S. Mole weight: 246.33.
H-Pro-NH2
An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Alternative Names: L-Prolinamide; (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-Pyrrolidine-2-carboxylic acid amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide; 2-Pyrrolidinecarboxamide, (2S)-; 2-Pyrrolidinecarboxamide, (S)-; Prolinamide, L-; (S)-Pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxylic acid amide; L-Proline amide. Grades: ≥95%. CAS No. 7531-52-4. Molecular formula: C5H10N2O. Mole weight: 114.10.
H-PRO-OIPR
H-PRO-OIPR. Alternative Names: H-PRO-OIPR; L-Proline, 1-methylethyl ester (9CI). CAS No. 61114-37-2. Molecular formula: C8H15NO2. Mole weight: 157.21.
H-Pro-pNA TFA
H-Pro-pNA TFA acts as a chromogenic substrate for prolyl aminopeptidase (proline iminopeptidase). Alternative Names: L-Proline 4-nitroanilide trifluoroacetate; (S)-N-(4-Nitrophenyl)-2-pyrrolidinecarboxamide Mono(trifluoroacetate); (2S)-N-(4-Nitrophenyl)-2-pyrrolidinecarboxamide Mono(trifluoroacetate); H-L-Pro-pNA Trifluoracetate; H-Pro-Pna TFA; L-Proline p-nitroanilide trifluoroacetate salt; Pro-pNA; P-pNA; H Pro Pna TFA; 2-Pyrrolidinecarboxamide, N-(4-nitrophenyl)-, (2S)-, mono(trifluoroacetate); 2-Pyrrolidinecarboxamide, N-(4-nitrophenyl)-, (S)-, mono(trifluoroacetate); 2-Pyrrolidinecarboxamide, N-(4-nitrophenyl)-, (2S)-, 2,2,2-trifluoroacetate (1:1). Grades: ≥95%. CAS No. 108321-19-3. Molecular formula: C11H13N3O3.C2HO2F3. Mole weight: 349.26.
H-Pro-Pro-Asp-NH2
H-Pro-Pro-Asp-NH2, adsorbed on modified silica gel, is a highly efficient recyclable chiral catalyst for aldol reactions. Alternative Names: H-PPD-NH2; L-prolyl-L-prolyl-L-isoasparagine; L-Prolyl-L-prolyl-L-α-asparagine; (S)-4-amino-4-oxo-3-((S)-1-((S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)butanoic acid. Grades: ≥95%. CAS No. 850440-85-6. Molecular formula: C14H22N4O5. Mole weight: 326.35.
H-Pro-Pro-Gln-OH
H-Pro-Pro-Gln-OH is an effective catalyst for conjugate addition reaction between aldehydes and β-substituted nitroolefins. Alternative Names: H-PPQ-OH; L-prolyl-L-prolyl-L-glutamine; Prolyl-prolyl-glutamine; (S)-5-amino-5-oxo-2-((S)-1-((S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)pentanoic acid. Grades: ≥95%. CAS No. 856170-98-4. Molecular formula: C15H24N4O5. Mole weight: 340.37.
H-PRO-PRO-PRO-PRO-OH
PPPP was used as an internal standard in the quantitative determination of the antihypertensive (ACE-inhibiting) peptides IPP and VPP in cheese by HPLC-MS3. Alternative Names: L-Pro-Pro-Pro-Pro. CAS No. 21866-90-0. Molecular formula: C20H30N4O5. Mole weight: 406.48.
H-Pro-Pro-Ser(OtBu)-NH2
H-Pro-Pro-Ser(OtBu)-NH2 is a protected tripeptide used in peptide synthesis. The H indicates a free N-terminus on the proline (Pro) residue, allowing for further coupling or reactions. The sequence includes two proline residues, which are known for introducing structural kinks or turns in peptide chains. The hydroxyl group of the serine (Ser) residue is protected by an OtBu (tert-butyl) group, which prevents it from reacting until selective deprotection. The -NH2 at the C-terminus denotes a free amine group, enabling additional modifications or coupling reactions. This peptide is utilized to introduce proline and serine into peptide sequences while controlling functional group reactivity through selective protection. Alternative Names: PPS; (S)-1-(L-Prolyl)-N-((S)-1-amino-3-(tert-butoxy)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide; H-Pro-Pro-Ser(tBu)-NH2. Grades: ≥95%. Molecular formula: C17H30N4O4. Mole weight: 354.45.
H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH
H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH, the p-nitrophenylalanine-containing substrate, is used for a convenient assay of pepsin and other aspartic proteinases of animal and microbial origin. It is soluble over a wide pH range with the Km values showing only little variation (Km = 80 μM at pH 3.1 and 37°C for porcine pepsin). Alternative Names: L-prolyl-L-threonyl-L-alpha-glutamyl-L-phenylalanyl-4-nitro-L-phenylalanyl-L-arginyl-L-leucine; PTEF-Nph-RL; L-Pro-L-Thr-L-Glu-L-Phe-4-Nitro-L-Phe-L-Arg-L-Leu-OH; (2S,5S,8S,11S,14S)-11-benzyl-5-(3-guanidinopropyl)-14-((2S,3R)-3-hydroxy-2-((S)-pyrrolidine-2-carboxamido)butanamido)-2-isobutyl-8-(4-nitrobenzyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazaheptadecane-1,17-dioic acid; L-Leucine, N-(N2-(4-nitro-N-(N-(N-(N-L-prolyl-L-threonyl)-L-alpha-glutamyl)-L-phenylalanyl)-L-phenylalanyl)-L-arginyl)-, (2'E)-; L-Prolyl-L-threonyl-L-α-glutamyl-L-phenylalanyl-4-nitro-L-phenylalanyl-N5-(diaminomethylene)-L-ornithyl-L-leucine. Grades: ≥95%. CAS No. 90331-82-1. Molecular formula: C44H63N11O13. Mole weight: 954.04.
hPTHrP (1-36) has been shown to be one of the authentic secretory forms of PTHrP. Alternative Names: Parathyroid hormone-related protein (1-36); Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-Glu-Ile. CAS No. 172867-62-8. Molecular formula: C191H305N59O52. Mole weight: 4260.10.
HPTU. Group: Biochemicals. Alternative Names: 1,1,3,3-Tetramethyl-2-(2-oxopyridin-1(2H)-yl)isouronium hexafluorophosphate. Grades: Highly Purified. CAS No. 364047-51-8. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C10H16F6N3O2P. US Biological Life Sciences.
Worldwide
HPV16-E711-20 epitope
HPV16-E711-20 epitope is a known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of HPV16-E7 protein, which binds to HLA-A2 with high affinity in vitro. Alternative Names: H-Tyr-Met-Leu-Asp-Leu-Gln-Pro-Glu-Thr-Thr-OH; L-tyrosyl-L-methionyl-L-leucyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-prolyl-L-alpha-glutamyl-L-threonyl-L-threonine. Grades: ≥95%. CAS No. 160040-04-0. Molecular formula: C53H83N11O19S. Mole weight: 1210.35.
HPV16 E7 86-93
HPV16 E7 86-93 is a human leukocyte antigen (HLA)-A2-restricted HPV16 E7 derived peptide that has immunogenicity in cervical cancer. Alternative Names: H-Thr-Leu-Gly-Ile-Val-Cys-Pro-Ile-OH; L-threonyl-L-leucyl-glycyl-L-isoleucyl-L-valyl-L-cysteinyl-L-prolyl-L-isoleucine. Grades: ≥95%. CAS No. 160212-93-1. Molecular formula: C37H66N8O10S. Mole weight: 815.03.
H-Pyr-Oet HCl. Alternative Names: ethyl (2S)-5-oxopyrrolidine-2-carboxylate hydrochloride. CAS No. 105210-68-2. Molecular formula: C7H11NO3·HCl. Mole weight: 193.7.
HpySE526 I
One unit of the enzyme is the amount required to hydrolyze 1 μg of pUC19 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 95% of the dna fragments can be ligated with t4 dna ligase and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. A↑CGT TGC↓A. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned HpySE 526I gene from Helicobacter pylori SE526. Pack: 10 mM Tris-HCl (pH 7.6); 100 mM NaCl; 0,1 mM EDTA; 200 μg/ml BSA; 1 mM DTT; and 50% glycerol. Cat No: ET-1123RE.
HQ005
HQ005 is a potent CCNK degrader with an DC50 value of 0.041 μM. HQ005 is a molecular-glue degrader that mediates interactions between target proteins and components of the ubiquitin-proteasome system to cause selective protein degradation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2750644-31-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148523.
HQ461
HQ461 is a molecular glue that promotes CDK12-DDB1 interaction to trigger cyclin K degradation. HQ461-mediated degradation of cyclin K impairs CDK12 function, resulting in decreased CDK12 substrate phosphorylation, downregulation of DNA damage response genes, and cell death[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1226443-41-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-144981.
HQL 79
HQL 79. Group: Biochemicals. Grades: Purified. CAS No. 162641-16-9. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
HQNO
HQNO, secreted by P. aeruginosa, is a potent electron transport chain inhibitor with a Kd of 64 nM for complex III[1]. HQNO is a potent inhibitor of mitochondrial NDH-2 in many species[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 341-88-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130055.
HQNO
It is produced by the strain of Pseudomonas pyocyanea, P. aeruginosa, P. methanica. HQNO is a quinolone inhibitor that blocks NADH oxidase (NADH) and Na+-dependent NADH-quinone reductase (NQR). It has weak anti-gram-positive bacterial activity. It can inhibit the microsomal respiratory chain and 5-lipoxygenase of cytochrome BC1 complex, and antagonize the antibacterial activity of dihydrostreptomycin. Alternative Names: Antibiotic KF 8940; 2-Heptyl-1-hydroxy-4-(1H)-quinolinone; 2-heptyl-4-hydroxyquinoline n-oxide; HOQNO; 2-Heptyl-4-quinolinol 1-oxide; 2-heptylquinolin-4-ol 1-oxide; 2-(n-Heptyl)-4-hydroxyquinoline N-oxide. Grades: ≥98%. CAS No. 341-88-8. Molecular formula: C16H21NO2. Mole weight: 259.34.
HQY1428
HQY1428 is an orally active CDK12 inhibitor. HQY1428 inhibits DNA replication, causes G2/M arrest in SKOV3 cells, induces DNA double-strand breaks and apoptosis. HQY1428 has anti-tumor activity in the SKOV3 xenograft mouse model. HQY1428 combined with the HER2 inhibitor Lapatinib (HY-50898) in the NCI-N87 xenograft mouse model produces a synergistic therapeutic effect[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3093763-71-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-172970.
HR-19011
HR-19011 is an eIF2α phosphorylation activator targeting heme-regulated inhibitor HRI (EIF2AK1). HR-19011 exhibits growth inhibitory activity against K562 cells with an IC50 value of 3.91?μM. HR-19011 inhibits the growth of hematologic malignancies by targeting HRI to activate the integrated stress response via the HRI-eIF2α-ATF4 axis. HR-19011 shows good safety in vivo. HR-19011 can be used for research on hematologic malignancies (leukemia)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2851820-52-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147831.