A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
HmdSL-37 is an antimicrobial peptide produced by Hylobates sp. (Gibbon, Hylobates moloch). It has antibacterial activity. Synonyms: Antibacterial protein LL-37; Ser-Leu-Gly-Asn-Phe-Phe-Arg-Lys-Ala-Arg-Lys-Lys-Ile-Gly-Glu-Glu-Phe-Lys-Arg-Ile-Val-Gln-Arg-Ile-Lys-Asp-Phe-Leu-Gln-His-Leu-Ile-Pro-Arg-Thr-Glu-Ala. Grade: ≥96%.
H-Met-2-Chlorotrityl Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
H-Met-2-Cl-Trt Resin
Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: L-Methionine-2-chlorotrityl resin.
H-Met-Ala-OH
H-Met-Ala-OH. Synonyms: Methionylalanine; MA dipeptide; Methionine Alanine dipeptide; (S)-2-((S)-2-Amino-4-(methylthio)butanamido)Propanoic acid. CAS No. 3061-96-9. Molecular formula: C8H16N2O3S. Mole weight: 220.29.
H-Met-Arg-Phe-Ala-OH is a substrate for dipeptidyl peptidase III from human erythrocytes and for snapalysin. It has been shown to be a competitive inhibitor of an enkephalin-generating endopeptidase isolated from rat brain. Synonyms: L-Methionyl-L-arginyl-L-phenylalanyl-L-alanine. CAS No. 67368-29-0. Molecular formula: C23H37N7O5S. Mole weight: 523.65.
H-MET-TRP-OH is an incomplete breakdown product of protein digestion or protein catabolism. It is a non-competitive inhibitor of angiotensin-1 converting enzyme (ACE), with an IC50 of 9.8 μM. Synonyms: Methionyltryptophan; L-Methionyl-L-tryptophan; Met-trp; L-Met-L-Trp; N-L-methionyl-L-tryptophan. Grade: 95%. CAS No. 60535-02-6. Molecular formula: C16H21N3O3S. Mole weight: 335.42.
H-Met-Trp-OH TFA salt
H-Met-Trp-OH TFA salt is an incomplete breakdown product of protein digestion or protein catabolism. It is a non-competitive inhibitor of angiotensin-1 converting enzyme (ACE). Synonyms: H-Met-Trp-OH Trifluoroacetate salt; L-methionyl-L-tryptophan trifluoroacetic acid; (S)-2-((S)-2-Amino-4-(methylthio)butanamido)-3-(1H-indol-3-yl)propanoic acid compound with 2,2,2-trifluoroacetic acid (1:1). Molecular formula: C16H21N3O3S.C2HF3O2. Mole weight: 449.45.
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-MeVal-Trt(2-Cl)-Resin; H-MeVal-Barlos Resin; N-Methyl-L-valine 2-chlorotrityl resin.
HMG499
HMG499 is a potent and selective HMG-CoA reductase inhibitor. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cholesterol levels and decrease atherosclerosis. CAS No. 2416941-68-7. Molecular formula: C33H54O3. Mole weight: 498.79.
HMG499
HMG499 is a potent and selective HMG-CoA reductase inhibitor with an IC50 of 0.41 μM. HMG499 can prevent statins-induced accumulation of HMGCR, reduce serum cholesterol levels and decrease atherosclerosis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2416941-68-7. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114316.
HMGB1 Antibody [N2J9]
HMGB1 Antibody [N2J9]. Group: Antibodies. Alternative Names: High mobility group protein B1; High mobility group protein 1; HMG-1; HMGB1; HMG1. Pack Sizes: 20uL. Product ID: F4213. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years.
United States; Europe
HMG-CoA
HMG-CoA is an intermediate in the mevalonate pathway. Synonyms: S-(Hydrogen 3-Hydroxy-3-methylglutarate) Coenzyme A; 3-Hydroxy-3-methylglutaryl CoA; 3-Hydroxy-3-methylglutaryl Coenzyme A; Hydroxymethylglutaryl CoA; Hydroxymethylglutaryl Coenzyme A; β-Hydroxy-β-methylglutaryl CoA; β-Hydroxy-β-methylglutaryl-coenzyme A. CAS No. 1553-55-5. Molecular formula: C27H44N7O20P3S. Mole weight: 911.66.
HMMNI is a metabolite of dimetridazole. Dimetridazole is an antibacterial and anticoccidial agent that is once widely used for the treatment of parasitic infections in livestock. Synonyms: 2-Hydroxymethyl-1-methyl-5-nitro-1H-imidazole; (1-Methyl-5-nitroimidazol-2-yl)methanol. CAS No. 936-05-0. Molecular formula: C5H7N3O3. Mole weight: 157.1.
HMMNI-d3
HMMNI-d3 (Hydroxy Dimetridazole-d3) is deuterium labeled HMMNI (HY-W008216). HMMNI (Hydroxy dimetridazole) is a hydroxy metabolite of Dimetridazol (HY-B1244). Dimetridazole is a nitroimidazole class agent that combats protozoan infections[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hydroxy Dimetridazole-d3. CAS No. 1015855-78-3. Pack Sizes: 1 mg; 5 mg. Product ID: HY-W008216S.
HMN-176 is an active metabolite of the synthetic antitumor compound HMN-214. HMN-176 shows potent cytotoxicity toward various human tumor cell lines, and in mitotic cells, it causes cell cycle arrest at M phase through the destruction of spindle polar bodies, followed by the induction of DNA fragmentation. However, no direct interactions of HMN-176 with tubulin are observed. Moreover, in animal models, it was observed that oral administration of the prodrug HMN-214 caused no significant nerve toxicity, a severe side effect often associated with microtubule binding agents such as Taxol and VCR.3 In Phase I clinical trials, HMN-214 has caused sensory neuropathy and ileus in some patients. However, the grade and frequency of these adverse effects were much lower than those of typical microtubule binding agents. As expected from the mechanism of action of HMN-214 (induction of G2-M arrest in dividing cells), the main adverse effect was neutropenia. Synonyms: HMN 176; HMN176; (E)-4-(2-(2-(N-((p-Methoxyphenyl)sulfonyl)amino)phenyl)ethenyl)pyridine 1-oxide. CAS No. 173529-10-7. Molecular formula: C20H18N2O4S. Mole weight: 382.43.
HMN-214
HMN-214 is an oral prodrug of HMN-176, a stilbene derivative that interferes with the subcellular spatial location of polo-like kinase-1, a serine/threonine kinase that regulates critical mitotic events. Synonyms: HMN-214; HMN 214. CAS No. 173529-46-9. Molecular formula: C22H20N2O5S. Mole weight: 424.471.
HMN-214
HMN-214, an orally bioavailable proagent of HMN-176, is an inhibitor of polo-like kinase-1 (plk1), with antitumor activity. Uses: Scientific research. Category: Signaling pathways. Alternative Names: IVX-214. CAS No. 173529-46-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-12045.
HMPA-AM Resin
HMPA-AM Resin. Alternative Names: 4-Hydroxymethylphenoxyacetyl aminomethyl polystyrene.
HMPA-AM Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
HM Pectin
HM Pectin.
HMR 1031
HMR 1031 is a potent and specific integrin α4β1 or very late antigen 4 (VLA-4) receptor antagonist binding to vascular cell adhesion molecule-1 (VCAM-1) and fibronectin. HMR1031 has the potential used as an inhaled drug for the treatment of asthma. Uses: Potential inhaled drug for asthma. Synonyms: HMR-1031; HMR 1031; HMR1031; Rnm7wqo98Y; (3S)-3-[[(2S)-2-[4,4-dimethyl-3-[[4-[(2-methylphenyl)carbamoylamino]phenyl]methyl]-2,5-dioxoimidazolidin-1-yl]-4-methylpentanoyl]amino]-3-phenylpropanoic acid. Grade: 98%. CAS No. 479203-71-9. Molecular formula: C35H41N5O6. Mole weight: 627.73.
HMR 1098
HMR 1098 is a KATP channel antagonist inactivating the ATP-sensitive potassium channels (KATP) responsible for potassium efflux. HMR 1098 is an inhibitor of Kir6.2/SUR1-composed K(ATP) channels. Synonyms: HMR 1098; HMR1098; HMR-1098; 5-chloro-2-methoxy-n-[2-[4-methoxy-3-(3-methylthioureidosulfonyl)phenyl]ethyl]benzamide sodium salt. Grade: 98%. CAS No. 261717-22-0. Molecular formula: C19H21ClN3NaO5S2. Mole weight: 493.96.
HMR 1556
HMR 1556 is a potent and selective Iks channel blocker (IC50 = 10.5 and 34 nM in canine and guinea pig ventricular myocytes, respectively). It selectively inhibits IKs currents over IKr, IKI, Ito and L-type Ca2+ channel currents. HMR 1556 also exhibits weak activity at Kv11.1 Kv1.5, Kv1.3, Kir2.1 and HCN2 channel currents. HMR 1556 is used in the treatment of proarrythmia. Uses: The treatment of proarrythmia. Synonyms: HMR-1556; HMR 1556; HMR1556.N-[(3R,4S)-3,4-Dihydro-3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy)-2H-1-benzopyran-4-yl]-N-methylmetanesulfonamide. Grade: ≥98% by HPLC. CAS No. 223749-46-0. Molecular formula: C17H24F3NO5S. Mole weight: 411.44.
HMR 1556
Potent and selective Iks channel blocker (IC50 values are 10.5 and 34nM in canine and guinea pig ventricular myocytes respectively). Selectively inhibits IKs currents over IKr, IKI, Ito and L-type Ca2+ channel currents. Also has little or no effect on Kv11.1 Kv1.5, Kv1.3, Kir2.1 and HCN2 channel currents. Potentiates E-4031-induced arrhythmias in vivo. Group: Biochemicals. Alternative Names: N- [ (3R, 4S) -3, 4-Dihydro-3-hydroxy-2, 2-di methyl -6- (4, 4, 4-trifluorobutoxy) -2H-1-benzopyran-4-yl] -N- methyl metanesulfonamide. Grades: Highly Purified. CAS No. 223749-46-0. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
HMR 1556
HMR 1556, a chromanol derivative, is a potent IKs blocker with IC50s of 10.5 nM and 34 nM in canine and guinea pig left ventricular myocytes, respectively[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 223749-46-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-106369.
HMR 1826
HMR 1826 is a heterodimeric lucuronide prodrug of doxorubicin, an anthracycline antibiotic commonly used to treat various cancers. Synonyms: 5,12-Naphthacenedione, 7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(2-hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[4-(β-D-glucopyranuronosyloxy)-3-nitrophenyl]methoxy]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-, (8S,10S)-; (8S-cis)-7,8,9,10-Tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[[2,3,6-trideoxy-3-[[[[4-(β-D-glucopyranuronosyloxy)-3-nitrophenyl]methoxy]carbonyl]amino]-α-L-lyxo-hexopyranosyl]oxy]-5,12-naphthacenedione; Doxorubicin-glucuronide. Grade: ≥95%. CAS No. 148580-25-0. Molecular formula: C41H42N2O22. Mole weight: 914.77.
HMWCNT Type1- Carbon Nanotubes Multi Walled Helical
HMWCNT Type1- Carbon Nanotubes Multi Walled Helical. CAS No. 308068-56-6.
HN-1
HN-1 is a cell-penetrating peptide that is absorbed only in adherent cells, not in suspended cells. Synonyms: H-Thr-Ser-Pro-Leu-Asn-Ile-His-Asn-Gly-Gln-Lys-Leu-OH; L-threonyl-L-seryl-L-prolyl-L-leucyl-L-asparagyl-L-isoleucyl-L-histidyl-L-asparagyl-glycyl-L-glutaminyl-L-lysyl-L-leucine. Grade: >98%. Molecular formula: C57H96N18O18. Mole weight: 1321.50.
H-N-3-Methyl-L-histidine
3-N-Methyl-L-histidine is a potential compound to be used as a treatment with pharmacological PPARα agonists to stimulate the ubiquitin proteasome pathway and myofibrillar protein breakdown in skeletal muscle of rodents. Synonyms: L-His(p-Me)-OH; H-His(3-Me)-OH; 3-methyl-L-histidine; H-His(p-Me)-OH; 3-N-Methyl-L-histidine; L-Histidine, 3-methyl-; METHYL-L-HISTIDINE,1-(RG). Grade: ≥ 99% (TLC). CAS No. 368-16-1. Molecular formula: C7H11N3O2. Mole weight: 169.18.
Hne
Hne. Alternative Names: (E)-4-HYDROXYNONENAL;HNE;4-HYDROXY-2-NONENAL;4-HNE;(+/-)-4-HYDROXY-2E-NONENAL;(+/-)-4-HYDROXYNON-2-ENAL;4-HYDROXYNONENAL;4-hydroxy-2-nonena. CAS No. 75899-68-2. Purity: 98%+. Product ID: ACM75899682. Molecular formula: C9H16O2. Mole weight: 156.22. IUPAC Name: (E)-4-hydroxynon-2-enal. Canonical SMILES: CCCCCC(C=CC=O)O. Alfa Chemistry - ISO 9001:32057 Certified.
HNGF6A
HNGF6A. Group: Biochemicals. Grades: Purified. CAS No. 1093111-54-6. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
HNGF6A
HNGF6A is a humanin analog that increases glucose stimulated insulin secretion and glucose metabolism in vivo and in vitro. HNGF6A enhances glucose sensing in βTC3 cells and decreases blood glucose level in Zucker diabetic fatty rats. HNGF6A is used for the prevention of endothelial dysfunction and atherosclerosis in vivo. Uses: The prevention of endothelial dysfunction and atherosclerosis. Synonyms: HNGF6A; 1093111-54-6; AKOS024458518; PD079802. CAS No. 1093111-54-6. Molecular formula: C112H198N34O31S2. Mole weight: 2581.13.
HNHA
HNHA is a cell-permeable inhibitor of histone deacetylase (HDAC) (IC50 = 100 nM). HNHA exhibits activity aganist various cancers like breast cancer and anaplastic thyroid cancer (ATC). Synonyms: Histone Deacetylase Inhibitor VI; N-hydroxy-7-naphthalen-2-ylsulfanylheptanamide. Grade: ≥98%. CAS No. 926908-04-5. Molecular formula: C17H21NO2S. Mole weight: 303.4.
H-NH-EtOEt-ol-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-NH-EtOEt-ol-Trt(2-Cl)-Resin; 2-(2-Aminoethoxy)ethanol-Trt(2-Cl)-Resin; 2-(2-Aminoethoxy)ethanol-2-chlorotrityl resin.
H-Nle-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Nle-Trt(2-Cl)-Resin; H-Nle-Barlos Resin; L-Norleucine 2-chlorotrityl resin.
H-(N-Me)Ala-2-Chlorotrityl Resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis.
HNMPA is a cell-impermeable insulin receptor tyrosine kinase inhibitor (IRTK). It inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Synonyms: Hydroxy-2-naphthalenylmethyl phosphonic acid. Grade: ≥95%. CAS No. 132541-52-7. Molecular formula: C11H11O4P. Mole weight: 238.2.
HNMPA-(AM)3
HNMPA-(AM)3 is a cell-permeable analog of HNMPA, an insulin receptor tyrosine kinase inhibitor (IRTK). It inhibits serine and tyrosine autophosphorylation by the human insulin receptor. Synonyms: Hydroxy-2-naphthalenylmethylphosphonic acid trisacetoxymethyl ester. Grade: ≥95%. CAS No. 120944-03-8. Molecular formula: C20H23O10P. Mole weight: 454.4.
hnps-PLA-IN-1
hnps-PLA-IN-1 is an inhibitor of human nonpancreatic secretory Phospholipase A. Synonyms: hnps-PLA Inhibitor; 2-(4-(2-Amino-2-oxoethoxy)-1-benzyl-2-ethyl-1H-indol-3-yl)-2-oxoacetamide; 2-{[1-benzyl-3-(carbamoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxy}acetamide. CAS No. 185298-58-2. Molecular formula: C21H21N3O4. Mole weight: 379.41.
hnRNPK-IN-1
hnRNPK-IN-1 is a heterogeneous nuclear ribonucleoprotein K (hnRNPK) binding ligand with Kds of 4.6 and 2.6 μM measured with SPR and MST, respectively. hnRNPK-IN-1 inhibits c-Myc transcription by disrupting the binding of hnRNPK and c-Myc promoter. It inducs apoptosis of Hela cells and shows strongly antitumor activity. Synonyms: 2-Propen-1-one, 1-(4-methoxyphenyl)-3-[4-(4-morpholinyl)-6-nitro-2-quinolinyl]-, (2E)-; (2E)-1-(4-Methoxyphenyl)-3-[4-(4-morpholinyl)-6-nitro-2-quinolinyl]-2-propen-1-one. Grade: ≥97%. CAS No. 2313528-04-8. Molecular formula: C23H21N3O5. Mole weight: 419.43.
hnRNPK-IN-1
hnRNPK-IN-1 is a heterogeneous nuclear ribonucleoprotein K (hnRNPK) binding ligand with Kd values of 4.6 μM and 2.6 μM measured with SPR and MST, respectively. hnRNPK-IN-1 inhibits c-myc transcription by disrupting the binding of hnRNPK and c-myc promoter. hnRNPK-IN-1 induces Hela cells apoptosis and has strongly anti-tumor activities[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2313528-04-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135691.
HNTU [2-(endo-5-Norbornene-2,3-dicarboxymido)-1,1,3,3-tetramethyluronium hexafluorophosphate]. Group: Biochemicals. Grades: Highly Purified. CAS No. 208462-94-6. Pack Sizes: 1g, 2g, 5g. US Biological Life Sciences.
Worldwide
H-Nva-2-chlorotrityl resin
2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Synonyms: H-Nva-Trt(2-Cl)-Resin; H-Nva-Barlos Resin; L-Norvaline 2-chlorotrityl resin.
HO-3867 is a selective and potent STAT3 inhibitor and shows good antitumor activity. Uses: Scientific research. Category: Signaling pathways. CAS No. 1172133-28-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100453.
HO-3867
HO-3867 is a selective and potent STAT3 inhibitor that selectively inhibits STAT3 phosphorylation, transcription, and DNA binding without affecting the expression of other active STATs. HO-3867 exhibited minimal toxicity toward noncancerous cells and tissues but induced apoptosis in ovarian cancer cells. Synonyms: HO 3867; EX-A2319; (3E,5E)-3,5-bis[(4-fluorophenyl)methylidene]-1-[(1-hydroxy-2,2,5,5-tetramethylpyrrol-3-yl)methyl]piperidin-4-one. Grade: >98%. CAS No. 1172133-28-6. Molecular formula: C28H30F2N2O2. Mole weight: 464.557.
HO-4120
Site-directed spin labeling of a genetically encoded unnatural amino acid. Group: Biochemicals. Alternative Names: 3-[(Aminooxy)methyl]-2,5-dihydro-2,2,5,5-tetramethyl-. Grades: Highly Purified. CAS No. 1214132-82-7. Pack Sizes: 2.5mg. US Biological Life Sciences.