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| Product | Description | |
|---|---|---|
| HIV-1 inhibitor-10 | HIV-1 inhibitor-10 is a nanomolar HIV-1 maturation inhibitor. Synonyms: 2-[(1R,3aS,5aR,5bR,7aR,11aS,11bR,13aR,13bR)-3a-carboxy-1-isopropenyl-5a,5b,8,8,11a-pentamethyl-1,2,3,4,5,6,7,7a,11,11b,12,13,13a,13b-tetradecahydrocyclopenta[a]chrysen-9-yl]spiro[3.3]hept-2-ene-6,6-dicarboxylic acid; 6-[28-Hydroxy-28-oxolupa-2,20(29)-dien-3-yl]spiro[3.3]hept-5-ene-2,2-dicarboxylic acid. Grade: ≥98% (HPLC). CAS No. 1449660-81-4. Molecular formula: C39H54O6. Mole weight: 618.84. |  |
| HIV-1 inhibitor-3 | HIV-1 inhibitor-3 is an inhibitor of HIV infection. (Extracted from patent US2018360927). Synonyms: 1-((2R,3R,4S,5S)-3,5-Difluoro-4-hydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl)pyrimidine-2,4(1H,3H)-dione; 1-(2-Deoxy-2,4-difluoro-beta-D-ribofuranosyl)uracil; Uridine, 2'-deoxy-2'-fluoro-4'-C-fluoro-. Grade: ≥95%. CAS No. 1612841-22-1. Molecular formula: C9H10F2N2O5. Mole weight: 264.18. | |
| HIV-1 inhibitor-60 | GSK2838232 is a novel human immune virus (HIV) maturation inhibitor being developed for the treatment of chronic HIV infection. GSK2838232 is a betulin derivative. Synonyms: 1443461-21-9; HIV-1 inhibitor-60; HIV Inhibitor GSK2838232; SCHEMBL15038672; EX-A202; HIV Inhibitor GSK2838232?; BDBM271422; BCP07297; US10064873, Example 45; GSK 2838232; AC-33624; HY-108255; CS-0027803; A926344; 4- (((3aR,5aR,5bR,7aR, 9S,11aR,11bR,13aS)- 3a-((R)-2-((3- Chlorobenzyl)(2- (dimethylamino)ethyl) amino)-1-hydroxyethyl)- 1-isopropyl- 5a,5b,8,8,11a- pentamethyl-2-oxo- 3,3a,4,5,5a,5b,6,7. Grade: 98%. CAS No. 1443461-21-9. Molecular formula: C48H73ClN2O6. Mole weight: 809.56. | |
| HIV-1 inhibitor-8 | HIV-1 inhibitor-8 is a potent, low-toxic and orally active HIV - 1 non-nucleoside reverse transcriptase inhibitor (NNRTI) with an IC50 of 0.081 μM against WT HIV-1 reverse transcriptase. It has particularly strong antiviral activity with EC50s of 4.44-54.5 nM against various HIV-1 strains. Synonyms: (E)-4-((4-(4-(2-cyanovinyl)-2,6-dimethylphenoxy)-7,8-dihydro-5H-thiopyrano[4,3-d]pyrimidin-2-yl)amino)benzonitrile. Molecular formula: C25H21N5OS. Mole weight: 439.53. | |
| HIV-1 inhibitor-9 | HIV-1 inhibitor-9 is a potent inhibitor against the wild-type (WT) HIV-1 strains or multiple NNRTI-resistant strains at low nanomolar levels. Synonyms: CHEMBL4875519|HIV-1 inhibitor-9|BDBM50575074|CS-0226407. Grade: ≥98% (HPLC). CAS No. 2708201-36-7. Molecular formula: C24H21N5O. Mole weight: 395.46. | |
| HIV-1 integrase inhibitor | HIV-1 integrase inhibitor is uesful for anti-HIV, which can target HIV-1 integrase and depress the activity in the treatment of HIV infection, AIDS, and other similar diseases characterized by integration of a retroviral genome into a host chromosome. Synonyms: (Z)-4-(3-(azidomethyl)phenyl)-2-hydroxy-4-oxobut-2-enoic acid. Grade: >98%. CAS No. 544467-07-4. Molecular formula: C11H9N3O4. Mole weight: 247.21. | |
| HIV-1 integrase inhibitor 2 | HIV-1 integrase inhibitor 2 is useful for anti-HIV, which can target HIV-1 integrase and depress the activity in the treatment of HIV infection, AIDS, and other similar diseases characterized by integration of a retroviral genome into a host chromosome. It did not affect integrase-DNA binding and only weakly inhibited the catalytic activities of integrase. Synonyms: CX04328; CX-04328; CX 04328; 3-Quinolineacetic acid, 6-chloro-2-methyl-4-phenyl-a-propyl-. Grade: >98%. CAS No. 957890-42-5. Molecular formula: C21H20ClNO2. Mole weight: 353.84. | |
| HIV-1 integrase inhibitor 3 | HIV-1 integrase inhibitor 3 is an HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 2.7 nM. Synonyms: 1,8-Naphthyridine-3-carboxamide, 4-amino-N-[(2,4-difluorophenyl)methyl]-1,2-dihydro-1-hydroxy-6-(5-hydroxypentyl)-2-oxo-; 4-Azanyl-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-6-(5-oxidanylpentyl)-1,8-naphthyridine-3-carboxamide; 4-Amino-N-(2,4-difluorobenzyl)-1-hydroxy-6-(5-hydroxypentyl)-2-oxo-1,2-dihydro-1,8-naphthyridine-3-carboxamide. Grade: ≥95%. CAS No. 1638504-56-9. Molecular formula: C21H22F2N4O4. Mole weight: 432.42. | |
| HIV-1 integrase inhibitor 4 | HIV-1 integrase inhibitor 4 is an HIV-1 integrase strand transfer (INST) inhibitor with an IC50 of 3.7 nM. Synonyms: 1,8-Naphthyridine-3-carboxamide, 4-amino-N-[(2,4-difluorophenyl)methyl]-1,2-dihydro-1-hydroxy-2-oxo-6-[2-(phenylsulfonyl)ethyl]-; 4-Azanyl-N-[[2,4-bis(fluoranyl)phenyl]methyl]-1-oxidanyl-2-oxidanylidene-6-[2-(phenylsulfonyl)ethyl]-1,8-naphthyridine-3-carboxamide; 4-Amino-N-(2,4-difluorobenzyl)-1-hydroxy-2-oxo-6-[2-(phenylsulfonyl)ethyl]-1,2-dihydro-1,8-naphthyridine-3-carboxamide. Grade: ≥95%. CAS No. 1638504-66-1. Molecular formula: C24H20F2N4O5S. Mole weight: 514.50. | |
| HIV-1 Nef-IN-1 | HIV-1 Nef-IN-1, an inhibitor of HIV-1 Nef protein, can effectively compete for Nef-SH3Hck interactions with a Kd of 6.7 μM. Synonyms: 4-(3-Phenanthryl)butanoic acid; 3-Phenanthrenebutanoic Acid; 3-Phenanthrenebutyric Acid; NSC 92828; 3-(1-Phenanthryl)butanoic acid; 1-Phenanthrenepropanoic acid, β-methyl-. Grade: ≥95%. CAS No. 13728-56-8. Molecular formula: C18H16O2. Mole weight: 264.32. | |
| HIV-1 Protease, Recombinant | HIV-1 protease is a retroviral aspartyl protease (retropepsin) that is essential for the life-cycle of HIV. HIV protease cleaves newly synthesized viral polyproteins at the appropriate places into functional protein products as mature protein components of an infectious HIV virion. The mutation of HIV protease's active site or inhibition of its activity disrupts HIVs ability to replicate and infect additional cells. Group: Enzymes. Synonyms: HIV-1 retropepsin; HIV-1 Protease (PR); cd05482. Enzyme Commission Number: EC 3.4.23.-. Purity: > 90%. Mole weight: 38.4 kDa (1-99 aa + N-terminal GST and C-terminal Poly-his tags). It runs at ~31 kDa during SEC and SDS-PAGE analyses. Activity: > 1mU/mg. Stability: Stable for at least 6 months as supplied. It can be further diluted to 0.5-1 mg/ml with 50 mM Sodium acetate, 100 mM NaCl, 5 mM DTT, 5 mM EDTA, pH 5.0 containing 10% glycerol, and stored at -80°C in aliquots. Do not keep the enzyme at 4°C or -20°C for extended time. Avoid repeated freezing and thawing cycles. Storage: Store at -80°C. Form: Liquid. Source: E. coli. HIV-1 retropepsin; HIV-1 Protease (PR); cd05482; HIV1 protease. Cat No: NATE-1662. |  |
| HIV-1 retropepsin | Present in human immunodeficiency virus type 1. Contributes to the maturation of the viral particle, and is a target of antiviral drugs. Active enzyme is a dimer of identical 11-kDa subunits. Similar enzymes occur in other retroviruses. Type example of peptidase family A2. Group: Enzymes. Synonyms: human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease. Enzyme Commission Number: EC 3.4.23.16. CAS No. 144114-21-6. HIV Protease. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4253; HIV-1 retropepsin; EC 3.4.23.16; 144114-21-6; human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease. Cat No: EXWM-4253. | |
| HIV-1 Rev 34-50 | HIV-1 Rev (34-50) is a 17-aa cell-penetrating peptide derived from HIV-1 Rev protein residue 34-50. It is an RNA-binding peptide that has been used to deliver macromolecules into cells. Synonyms: H-Thr-Arg-Gln-Ala-Arg-Arg-Asn-Arg-Arg-Arg-Arg-Trp-Arg-Glu-Arg-Gln-Arg-OH; HIV-1 Rev Protein (34-50); L-Arginine, L-threonyl-L-arginyl-L-glutaminyl-L-alanyl-L-arginyl-L-arginyl-L-asparaginyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-α-glutamyl-L-arginyl-L-glutaminyl-; Revprotein (Human immunodeficiency virus 1 fragment); L-threonyl-L-arginyl-L-glutaminyl-L-alanyl-L-arginyl-L-arginyl-L-asparagyl-L-arginyl-L-arginyl-L-arginyl-L-arginyl-L-tryptophyl-L-arginyl-L-alpha-glutamyl-L-arginyl-L-glutaminyl-L-arginine; Rev34-50; HIV-1 Rev (34-50). Grade: ≥95%. CAS No. 141237-50-5. Molecular formula: C97H173N51O24. Mole weight: 2437.74. | |
| HIV-1 TAT (48-60) | HIV-1 TAT (48-60) is a cell-penetrating peptide generated from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way. Synonyms: H-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-Pro-Pro-Gln-OH; glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginyl-L-prolyl-L-prolyl-L-glutamine. Grade: ≥95%. Molecular formula: C70H131N35O16. Mole weight: 1719.04. | |
| HIV-1 TAT (48-60) | HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. It has been used to deliver exogenous macromolecules into cells in a non-disruptive way. Uses: Scientific research. Category: Signaling pathways. CAS No. 220408-24-2. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P1491. |  |
| HIV-1 Tat Protein (47-57) | HIV-1 Tat Protein (47-57). Uses: For analytical and research use. CAS No. 191936-91-1. Mole weight: 1559.83. Catalog: AP191936911. |  |
| HIV-1 TAT Protein Peptide | It is a cell-permeable peptide (CPP) derived from the HIV-1 tat protein transduction domain (PTD), which has been shown to promote the entry of nucleic acids into several cell types. Synonyms: HIV-1 Tat Protein (47-57); H-Tyr-Gly-Arg-Lys-Lys-Arg-Arg-Gln-Arg-Arg-Arg-OH; TAT (47-57); L-tyrosyl-glycyl-L-arginyl-L-lysyl-L-lysyl-L-arginyl-L-arginyl-L-glutaminyl-L-arginyl-L-arginyl-L-arginine. Grade: 98%. CAS No. 191936-91-1. Molecular formula: C64H118N32O14. Mole weight: 1559.83. | |
| HIV-2 Peptide | HIV-2 Peptide. Synonyms: HIV-2 env Protein gp41 (86-104); H-Lys-Asp-Gln-Ala-Gln-Leu-Asn-Ser-Trp-Gly-Cys-Ala-Phe-Arg-Gln-Val-Cys-His-Thr-OH (Disulfide bridge: Cys11-Cys17). Grade: ≥95%. CAS No. 172486-63-4. Molecular formula: C93H140N30O28S2. Mole weight: 2190.45. | |
| HIV-2 Protease, Recombinant | HIV-2 Protease, an aspartyl protease (retropepsin), is essential for the life-cycle of HIV-2 sub-type virus. It is expressed in the infected cells as a part of Gag-Pol polyprotein from which it is auto-catalytically released after formation of an immature viral particle. The enzyme subsequently cleaves the other parts of viral polyproteins resulting in the maturation of the virus. In HIV-infected patients, the enzyme is subjected to intensive mutagenesis and mutants resistant to applied medicines are produced as a result of the selection pressure. The mutation of HIV protease's active site or inhibition of its activity disrupts HIVs ability to replicate and infect additional ce.epsin; HIV-2 Protease (PR2); cd05482. Enzyme Commission Number: EC 3.4.23.-. Purity: > 85%. Mole weight: 38.3 kDa (1-99 aa + N-terminal GST and C-terminal Poly-his tags). It runs at ~31.5 kDa during SEC and SDS-PAGE analyses. Stability: Stable for at least 6 months as supplied. It can be further diluted to 0.5-1 mg/ml with 50 mM Sodium acetate, 100 mM NaCl, 5 mM DTT, 5 mM EDTA, pH 5.0 containing 10% glycerol, and stored at -80°C in aliquots. Do not keep the enzyme at 4°C or -20°C for extended time. Avoid repeated freezing and thawing cycles. Storage: Store at -80°C. Form: Liquid. Source: E. coli. HIV-2 retropepsin; HIV-2 Protease (PR2); cd05482; HIV2 protease. Cat No: NATE-1661. | |
| HIV-2 retropepsin | In peptidase family A2. Responsible for the post-translational processing of the human immunodeficiency virus polyprotein. Group: Enzymes. Enzyme Commission Number: EC 3.4.23.47. CAS No. 144114-21-6. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4284; HIV-2 retropepsin; EC 3.4.23.47; 144114-21-6. Cat No: EXWM-4284. | |
| H-Iva-Ome HCl | H-Iva-Ome HCl. Synonyms: (S)-Methyl 2-amino-2-methylbutanoate hydrochloride; (S)-2-amino-2-methylbutyric acid methyl ester hydrochloride; H Iva Ome HCl. Grade: 95%. CAS No. 92760-72-0. Molecular formula: C6H14ClNO2. Mole weight: 167.63. | |
| Hivernal® Neo | Hivernal® Neo. CAS No. 300371-33-9. Kosher: Y. VIGON Item # 508452. Categories: Speciality Ingrdients Suppliers, Fragrances, Perfumers. |  America & Internationally |
| HIV gag peptide 197-205 | HIV gag peptide 197-205 is an H-2Kd-restricted epitope consisting of amino acids 197-205 derived from the p24 portion of HIV-1 gag protein. Synonyms: H-Ala-Met-Gln-Met-Leu-Lys-Glu-Thr-Ile-OH; L-alanyl-L-methionyl-L-glutaminyl-L-methionyl-L-leucyl-L-lysyl-L-alpha-glutamyl-L-threonyl-L-isoleucine. Grade: ≥95%. CAS No. 214978-47-9. Molecular formula: C45H81N11O14S2. Mole weight: 1064.32. | |
| HIV-IN-8 | HIV-IN-8 is a HIV inhibitor. Synonyms: (2R)-2-(3-{[(1R)-2-(3,4-Dihydroxyphenyl)-1-carboxyethyl]oxycarbonyl}(4S,3R)-4-(3,4-dihydroxyphenyl)-6,7-dihydroxy(2-3,4-dihydronaphthylcarbonyloxy))-3-(3,4-dihydroxyphenyl)propanoic acid; (2R)-3-(3,4-dihydroxyphenyl)-2-[(1S,2R)-1-(3,4-dihydroxyphenyl)-3-[(1R)-1-[(3,4-dihydroxyphenyl)methyl]-2-hydroxy-2-oxo-ethoxy]carbonyl-6,7-dihydroxy-1,2-dihydronaphthalene-2-carbonyl]oxy-propanoic acid. CAS No. 130286-75-8. Molecular formula: C36H30O16. Mole weight: 718.61. | |
| HIV-IN petide | Arg-Val-Leu-(R)-Phe-Glu-Ala-Nle-NH2 contains a reduced peptide bond and is a competitive inhibitor of the HIV-1 protease with a Ki of 50 nM. Synonyms: 167875-35-6; HIV-IN petide; H-Arg-Val-Leu-psi(CH2NH)Phe-Glu-Ala-Nle-NH2; (4S)-4-[[(2S)-2-[[(2S)-2-[[(2S)-2-[[(2S)-2-amino-5-(diaminomethylideneamino)pentanoyl]amino]-3-methylbutanoyl]amino]-4-methylpentyl]amino]-3-phenylpropanoyl]amino]-5-[[(2S)-1-[[(2S)-1-amino-1-oxohexan-2-yl]amino]-1-oxopropan-2-yl]amino]-5-oxopentanoic acid; Arg-Val-Leu-(R)-Phe-Glu-Ala-Nle-NH2; 107475-09-2; N-[(2r)-2-({n~5~-[amino(Iminio)methyl]-L-Ornithyl-L-Valyl}amino)-4-Methylpentyl]-L-Phenylalanyl-L-Alpha-Glutamyl-L-Alanyl-L-Norleucinamide; 2aoe; 0Q4; Peptide Inhibitor CA/p2; N-1270; R-V-L-r-F-E-A-Nle; BDBM13935; HY-P4543; MFCD00237446; H-Arg-Val-Leu-r-Phe-Glu-Ala-Nle-NH2; DA-53842; CS-0655006; (4S)-4-[(2S)-2-{[(2S)-2-[(2S)-2-[(2S)-2-amino-5-carbamimidamidopentanamido]-3-methylbutanamido]-4-methylpentyl]amino}-3-phenylpropanamido]-4-{[(1S)-1-{[(1S)-1-carbamoylpentyl]carbamoyl}ethyl]carbamoyl}butanoic acid. Grade: ≥95%. CAS No. 167875-35-6. Molecular formula: C40H69N11O8. Mole weight: 832.04. | |
| HIV p17 Gag 77-85 | HIV p17 Gag 77-85 is used in the research of anti-HIV. Synonyms: HIV-1 gag Protein p17 (76-84); H-Ser-Leu-Tyr-Asn-Thr-Val-Ala-Thr-Leu-OH; L-seryl-L-leucyl-L-tyrosyl-L-asparagyl-L-threonyl-L-valyl-L-alanyl-L-threonyl-L-leucine; HIV P17 GAG (77-85). Grade: ≥95%. CAS No. 147468-65-3. Molecular formula: C44H72N10O15. Mole weight: 981.10. | |
| HIV Protease Mutant, Recombinant | HIV-1 protease is a retroviral aspartyl protease (retropepsin) that is essential for the life-cycle of HIV, the retrovirus that causes AIDS. HIV protease cleaves newly synthesized polyproteins at the appropriate places to create the mature protein components of an infectious HIV virion. Without effective HIV protease, HIV virions remain uninfectious. Thus, mutation of HIV protease's active site or inhibition of its activity disrupts HIVs ability to replicate and infect additional cells, making HIV protease inhibition the subject of considerable pharmaceutical research. Group: Enzymes. Synonyms: human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease; HIV-1 retropepsin; HIV Protease Mutant; EC 3.4.23.16. Enzyme Commission Number: EC 3.4.23.16. CAS No. 144114-21-6. HIV Protease. Mole weight: mol wt ~10.8 kDa. Storage: -70°C. Form: Supplied as a solution in 0.5M Sodium Acetate, pH 4.7with 50mM Tris-HCL, 1M NaCL, 1mM EDTA, 5mM DTT and 15% glycerol. Source: E. coli. human immunodeficiency virus type 1 protease; gag protease; HIV aspartyl protease; HIV proteinase; retroproteinase; HIV-1 protease; HIV-2 protease; HIV-1 retropepsin; HIV Protease Mutant; EC 3.4.23.16. Pack: 100 unit vial containing > 100ug protein. Cat No: NATE-0344. | |
| HIV Protease Substrate VI | HIV Protease Substrate VI is a sensitive chromogenic substrate for both HIV-1 and HIV-2 proteases. Synonyms: H-Arg-Val-Nle-p-nitro-Phe-Glu-Ala-Nle-NH2; L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-alpha-glutamyl-L-alanyl-L-norleucinamide; L-Norleucinamide, L-arginyl-L-valyl-L-norleucyl-4-nitro-L-phenylalanyl-L-α-glutamyl-L-alanyl-. Grade: ≥95%. CAS No. 130877-92-8. Molecular formula: C40H66N12O11. Mole weight: 891.04. | |
| HJ445A | HJ445A is a potent MYOF inhibitor and binds to the MYOF-C2D domain with a KD of 0.17 μM. HJ445A potently repressed the proliferation of gastric cancer cells with IC50 values of 0.16 and 0.14 μM in MGC803 and MKN45, respectively. HJ445A demonstrates superior antitumor efficacy in vivo and can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3032441-59-8. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-163084. | |
| HJB97 | HJB97 is a high-affinity BET inhibitor with Ki values of 0.9 nM (BRD2 BD1), 0.27 nM (BRD2 BD2), 0.18 nM (BRD3 BD1), 0.21 nM (BRD3 BD2), 0.5 nM (BRD4 BD1), and 1.0 nM (BRD4 BD2)[1]. HJB97 can serve as a ligand for target protein (Ligands for Target Protein for PROTAC) for the development of PROTAC BET degraders with antitumor activity[1]. HJB97 can be used for the synthesis of BETd-260 (HY-101519). Uses: Scientific research. Category: Signaling pathways. CAS No. 2093391-24-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112429. | |
| HJC-0123 | HJC-0123 is a potent and selective STT 3 inhibitor. HJC0123 has demonstrated to inhibit STAT3 promoter activity, downregulate phosphorylation of STAT3, increase the expression of cleaved caspase-3, inhibit cell cycle progression and promote apoptosis in breast and pancreatic cancer cells with low micromolar to nanomolar IC50 values. Furthermore, HJC-0123 significantly suppressed estrogen receptor (ER)-negative breast cancer MDA-MB-231 xenograft tumor growth in vivo (p.o.), indicating its great potential as an efficacious and orally bioavailable drug candidate for human cancer therapy. Synonyms: HJC 0123; HJC0123; 2-Phenyl-quinoline-4-carboxylic acid (1,1-dioxo-1H-1lambda6-benzo[b]thiophen-6-yl)-amide. Grade: 98%. CAS No. 1430420-02-2. Molecular formula: C24H16N2O3S. Mole weight: 412.46. | |
| HJC0152 | HJC0152 Inhibitor. Uses: Scientific use. Product Category: T4234. CAS No. 1420290-99-8. |  |
| HJC0152 | HJC0152 is a signal transducers and activators of transcription 3 (STAT3) inhibitor. Uses: Scientific research. Category: Signaling pathways. CAS No. 1420290-99-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100602. | |
| HJC0197 | HJC0197 is an erythromycin propionate-N-acetylcysteinate inhibitor (EPAC) with IC50 value of 5.9 μM for Epac2. HJC0197 can inhibit Epac1-mediated Rap1-GDP exchange activity at 25 μM, but it has no effect on cAMP-induced type I and II PKA activity at this concentration. HJC0197 can be used to study the role of Epac signaling in chondrogenesis in chicken micromass cultures. EPAC inhibitor may prevent pancreatic cancer cell migration and invasion. Uses: Study the role of epac signaling. Synonyms: HJC-0197; HJC 0197; 4-cyclopentyl-2-((2,5-dimethylbenzyl)thio)-6-oxo-1,6-dihydropyrimidine-5-carbonitrile. Grade: 98%. CAS No. 383539-73-8. Molecular formula: C19H21N3OS. Mole weight: 339.45. | |
| HJC0350 | HJC0350 is a potent and Epac2-specific inhibitor with IC50 of 0.3 μM, exhibiting no inhibition on Epac1. Synonyms: HJC 0350; HJC-0350; 1-(mesitylsulfonyl)-2,4-dimethyl-1H-pyrrole. Grade: >98%. CAS No. 885434-70-8. Molecular formula: C15H19NO2S. Mole weight: 277.38. | |
| HJC 0350 | HJC 0350. Group: Biochemicals. Grades: Purified. CAS No. 885434-70-8. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. |  Worldwide |
| HJC0416 hydrochloride | HJC0416 hydrochloride is a potent anticancer agent, an orally bioavailable small molecule inhibitor of signal transducer and activator of transcription 3 (STAT3). Synonyms: HJC0416 (hydrochloride). CAS No. 2415263-08-8. Molecular formula: C18H18Cl2N2O4S. Mole weight: 429.32. | |
| HK-2-IN-1 | HK-2-IN-1 is a Hexokinase 2 (HK-2) inhibitor. HK-2-IN-1 exhibits a non-activating effect on human recombinant HK-2 enzyme. HK-2-IN-1 has anti-tumor activity, affecting immune cells in the tumor microenvironment. HK-2-IN-1 has immunomodulatory effects and is potentially useful in the study of cancers such as colon cancer, liver cancer, and breast cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3114833-48-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-175035. | |
| HKB99 | HKB99 is an allosteric inhibitor of phosphoglycerate mutase 1 (PGAM1). HKB99 induces apoptosis. HKB99 inhibits the formation of invasive pseudopodia and inhibits migration. HKB99 increases the oxidative stress, activates JNK/c-Jun and suppresses AKT and ERK. HKB99 can be used for the research of non-small-cell lung cancer (NSCLC)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2414908-90-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-148510. | |
| H+/K+-exchanging ATPase | A P-type ATPase that undergoes covalent phosphorylation during the transport cycle. A gastric mucosal enzyme that catalyses the efflux of one H+ and the influx of one K+ per ATP hydrolysed. Group: Enzymes. Synonyms: H+-K+-ATPase; H,K-ATPase; (K+ + H+)-ATPase. Enzyme Commission Number: EC 3.6.3.10. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4647; H+/K+-exchanging ATPase; EC 3.6.3.10; H+-K+-ATPase; H,K-ATPase; (K+ + H+)-ATPase. Cat No: EXWM-4647. | |
| HKGreen-4I | HKGreen-4I is a highly sensitive green fluorescent probe for the specific detection of ONOO- in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1448821-82-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-D1148. | |
| HK-HELP survivin | HK-HELP survivin. Synonyms: Glu-His-Lys-Lys-His-Ser-Ser-Gly-Cys-Ala-Phe-Leu-Ser-Val-Lys-Lys-Gln-Phe-Glu-Gly-Gly-Gly-Gly-Gly-Gly-Phe-Leu-Lys-Leu-Asp-Arg-Glu-Arg-Ala-Lys-Asn-Lys-Gly-Gly-Gly. | |
| HK-HELP WT-1 | HK-HELP WT-1. Synonyms: Arg-Met-Phe-Pro-Asn-Ala-Pro-Tyr-Leu-Gly-Gly-Gly-Gly-Gly-Lys-Arg-Tyr-Phe-Lys-Leu-Ser-His-Leu-Gln-Met-His-Ser-Arg-Lys-His-Gly-Gly-Gly-Gly-Gly-Cys-Tyr-Thr-Trp-Asn-Gln-Met-Asn-Leu. | |
| HKI 357 | HKI 357 is a potent and irreversible dual inhibitor of ErbB2 (HER2) and EGFR (IC50 = 33 and 34 nM, respectively). It inhibits EGFR autophosphorylation and proliferation of NCI-H1975 cells containing L858R and T790M mutations. Uses: Antitumor agent. Synonyms: HKI 357; HKI357; HKI-357; (2E)-N-[[4-[[(3-Chloro-4-[(3-fluorophenyl)methoxy]phenyl]amino]-3-cyano-7-ethoxy-6-quinolinyl]-4-(dimethylamino)-2-butenamide. Grade: ≥98% by HPLC. CAS No. 848133-17-5. Molecular formula: C31H29ClFN5O3. Mole weight: 574.05. | |
| HKI 357 | HKI 357. Group: Biochemicals. Grades: Purified. CAS No. 848133-17-5. Pack Sizes: 10mg, 50mg. US Biological Life Sciences. | Worldwide |
| HKI-357 | HKI-357 is an irreversible dual inhibitor of EGFR and ERBB2 with IC50s of 34 nM and 33 nM, respectively. HKI-357 suppresses EGFR autophosphorylation (at Y1068), and AKT and MAPK phosphorylation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 848133-17-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103443. | |
| HKOCl-3 | HKOCl-3 is a highly sensitive and selective fluorescent probe for detecting hypochlorous acid.Ex: 490 nm; Em 527 nm[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2031170-80-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-130025. | |
| HKOH-1r | HKOH-1r is a highly sensitive green fluorescent probe for the specific detection of ·OH in living cells with a maximum excitation wavelength and emission wavelength of 500 nm and 520 nm, respectively[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2138472-08-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-D1159. | |
| HKPao | HKPao (Hunter-killer peptide ao) is a biologically active peptide. HKPao (Hunter-killer peptide ao) has anti-obesity and anti-tumor pro-apoptotic activity to cause release of cytochrome c from vesicles[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hunter-killer peptide ao; Prohibitin-targeting peptide 1; prohibitin-TP01; Adipotide. CAS No. 859216-15-2. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P3586. | |
| HKPerox-1 | HKPerox-1 is a highly sensitive green fluorescent probe for the specific detection of H2O2 in living cells with a maximum excitation wavelength and emission wavelength of 520 nm and 543 nm, respectively[2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2240163-05-5. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-130022. | |
| HKPLP | HKPLP is an antibacterial peptide isolated from Hippocampus kuda. Synonyms: Phe-Leu-Gly-Leu-Ile-Phe-His-Gly-Leu-Val-His-Ala-Gly-Lys-Leu-Ile-His-Gly-Leu-Ile-His-Arg-Asn-Arg-Gly. Grade: 96.1%. | |
| HKYK-0030 | HKYK-0030 is an inhibitor for MTDH-SND1 protein-protein interaction. HKYK-0030 exhibits inhibitory activity against cancer metastasis[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2923054-94-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160801. | |
| HL 010183 | HL 010183 is a metformin derivative exhibiting potent antitumor effect. It inhibits proliferation and invasion of Hs578T triple-negative (TN) breast cancer cells. Uses: Antitumor agent. Synonyms: HL 010183; HL010183; HL-010183. Grade: 99%. CAS No. 1429218-03-0. Molecular formula: C14H20N6.HCl. Mole weight: 308.81. | |
| HL-60 Electroporation Kit | Electroporation buffer optimized for HL60 Plasmacytoma Cells. Optimized electroporation protocol provided for transfection of si/miRNA, DNA, mRNA, and small proteins. Feature high transfection efficacy and cell viability. Uses: Electroporation of DNA, RNA, protein and small molecules. Product ID: 1752. |  Nevada, Texas, USA |
| H-labda-3,13(16),14-trien-18-ol, 15,16-epoxy-5,9-dimethyl-, (-)- | H-labda-3,13(16),14-trien-18-ol, 15,16-epoxy-5,9-dimethyl-, (-)-. Synonyms: 17,19-Dinor-5β,9βH-labda-3,13(16),14-trien-18-ol, 15,16-epoxy-5,9-dimethyl-, (-)- (8CI). CAS No. 20055-60-1. Molecular formula: C20H30O2. Mole weight: 302.45. | |
| HLA class II histocompatibility antigen, DO beta chain (232-240) | HLA class II histocompatibility antigen, DO beta chain (232-240) is a bioactive peptide of HLA class II histocompatibility antigen, DO beta chain. HLA class II histocompatibility antigen, DO beta chain binds peptides derived from antigens that access the endocytic route of antigen presenting cells (APC) and presents them on the cell surface for recognition by the CD4 T-cells. Synonyms: HLA class II histocompatibility antigen, DX beta chain (232-240); MHC class II antigen DQB2 (232-240). | |
| HLCL61 | HLCL61 is a potent and selective protein arginine methyltransferase 5 (PRMT5) inhibitor. It is used for treatment of acute myeloid leukemia. It resulted in significantly increased expression of miR-29b and consequent suppression of Sp1 and FLT3 in acute myeloid leukemia cells. Uses: Hlcl61 is used for treatment of acute myeloid leukemia. Synonyms: HLCL-61; HLCL 61; 9-Ethyl-N-[(2-methoxyphenyl)methyl]-9H-carbazole-3-methanamine. Grade: 98%. CAS No. 586395-74-6. Molecular formula: C23H24N2O. Mole weight: 344.19. | |
| HLCL-61 hydrochloride | The hydrochloride salt form of HLCL-61, an effective inhibitor of PRMT5, could probably useful in the treatment of acute myeloid leukemia. Uses: The hydrochloride salt form of hlcl-61 is an effective inhibitor of prmt5 and could probably useful in the treatment of acute myeloid leukemia. Synonyms: 1-(9-ethyl-9H-carbazol-3-yl)-N-(2-methoxybenzyl)methanamine hydrochloride; HLCL61; HLCL 61; HLCL-61. Grade: 98%. CAS No. 1158279-20-9. Molecular formula: C23H25ClN2O. Mole weight: 380.91. | |
| HLCL-61 hydrochloride | HLCL-61 hydrochloride is a first-in-class inhibitor of protein arginine methyltransferase 5 (PRMT5). Uses: Scientific research. Category: Signaling pathways. CAS No. 1158279-20-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100025A. | |
| HLCL65 hydrochloride | HLCL65 hydrochloride is a first-in-class inhibitor of PRMT5. HLCL65 selectively inhibits Th1 cell proliferation (IC50 value 1.1 μM). In vivo, HLCL65 suppresses recall T cell responses and reduces inflammation in delayed-type hypersensitivity and clinical disease in experimental autoimmune encephalomyelitis mouse models; In vitro, HLCL65 effectively inhibits symmetric arginine dimethylation (me2) of histones H3 and H4 in AML samples. Synonyms: HLCL65 hydrochloride; HLCL 65 hydrochloride; HLCL-65 hydrochloride; 1-(6-bromo-9-ethylcarbazol-3-yl)-N-[(2-methoxyphenyl)methyl]methanamine hydrochloride. Grade: 99%. Molecular formula: C23H23BrN2O.HCl. Mole weight: 459.81. | |
| HLDA-221 | HLDA-221 is a non-covalent regulated induced proximity targeting chimeras (RIPTAC). The binding of HLDA-221 to BRD4-BD1 is significantly increased after pre-incubation with FKBP. HLDA-221 can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3077339-82-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-156820. | |
| H-Leu-2-Chlorotrityl Resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. | |
| H-Leu-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: L-Leucine-2-chlorotrityl resin. |  |
| H-Leu-Ala-Ala-Val-Ser-Asp-Leu-Asn-Pro-Asn-Ala-Pro-Arg-OH | H-Leu-Ala-Ala-Val-Ser-Asp-Leu-Asn-Pro-Asn-Ala-Pro-Arg-OH. Synonyms: L-leucyl-L-alanyl-L-alanyl-L-valyl-L-seryl-L-alpha-aspartyl-L-leucyl-L-asparagyl-L-prolyl-L-asparagyl-L-alanyl-L-prolyl-L-arginine; L-Leucyl-L-alanyl-L-alanyl-L-valyl-L-seryl-L-α-aspartyl-L-leucyl-L-asparaginyl-L-prolyl-L-asparaginyl-L-alanyl-L-prolyl-N5-(diaminomethylene)-L-ornithine. Grade: ≥95%. CAS No. 415684-36-5. Molecular formula: C57H96N18O19. Mole weight: 1337.48. | |
| H-LEU-ARG-ARG-TRP-SER-LEU-GLY-OH | H-LEU-ARG-ARG-TRP-SER-LEU-GLY-OH. Synonyms: (Trp4)-Kemptide; Chocktide; N-[17-Amino-11,14-bis(3-carbamimidamidopropyl)-1,4,7,10,13,16-hexahydroxy-5-(hydroxymethyl)-8-[(1H-indol-3-yl)methyl]-19-methyl-2-(2-methylpropyl)-3,6,9,12,15-pentaazaicosa-3,6,9,12,15-pentaen-1-ylide. CAS No. 80224-16-4. Molecular formula: C40H66N14O9. Mole weight: 887. | |
| H-LEU-ASN-OH | H-LEU-ASN-OH. Synonyms: Leu-Asn; L-leucyl-L-asparagine; L-Leu-L-Asn; Leucyl-asparagin. Grade: >99%. CAS No. 14608-81-2. Molecular formula: C10H19N3O4. Mole weight: 245.28. | |
| H-Leu-Asp-OH | H-Leu-Asp-OH. Synonyms: Leu-Asp; L-leucyl-L-aspartic acid; Leucyl-Aspartate; L-Leu-L-Asp. Grade: 95%. CAS No. 32949-40-9. Molecular formula: C10H18N2O5. Mole weight: 246.26. | |
| H-Leucinol-2-chlorotrityl resin | Pre-loaded resins for solid phase peptide and organic synthesis. Synonyms: L-Leu-ol-2-chlorotrityl resin. | |
| H-Leu-Gly-Ile-Ala-Gly-Arg-OH | H-Leu-Gly-Ile-Ala-Gly-Arg-OH. Synonyms: L-Argininamide, N-(2,4-dinitrophenyl)-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-; 2,4-Dinitrophenyl-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-argininamide; N-(2,4-Dinitrophenyl)-L-leucylglycyl-L-isoleucyl-L-alanylglycyl-L-arginamide. CAS No. 60343-97-7. Molecular formula: C31H50N12O10. Mole weight: 750.80. | |
| H-Leu-Gly-Leu-Leu-Leu-Arg-His-Leu-Arg-His-His-Ser-Asn-Leu-Leu-Ala-Asn-Ile-OH | H-Leu-Gly-Leu-Leu-Leu-Arg-His-Leu-Arg-His-His-Ser-Asn-Leu-Leu-Ala-Asn-Ile-OH, the peptide sequence B18 derived from membrane-associated sea urchin sperm protein-binding proteins, triggers fusion between lipid vesicles. It has many similarities with viral fusion peptides. Grade: ≥95%. CAS No. 222557-92-8. Molecular formula: C94H160N32O22. Mole weight: 2090.48. | |
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