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| Product | Description | |
|---|---|---|
| HPK1-IN-13 | HPK1-IN-13 is a potent inhibitor of HPK1 extracted from patent WO2021213317A1, compound 64. HPK1-IN-13 has the potential for the research of HPK1 related diseases. Uses: It is being investigated for its potential use in the treatment of cancer and other diseases. CAS No. 2734168-30-8. Molecular formula: C25H24FN5O2. Mole weight: 445.49. |  |
| HPK1-IN-14 | HPK1-IN-14 is a potent inhibitor of HPK1 extracted from patent WO2021213317A1, compound 79. HPK1-IN-14 has the potential for the research of HPK1 related diseases. Synonyms: N-(2-fluorobenzyl)-6-(2-hydroxy-5-nitrobenzylidene)-4-pyrimidinamine. CAS No. 2734168-45-5. Molecular formula: C24H23FN6O2. Mole weight: 446.48. | |
| HPK1-IN-15 | HPK1-IN-15 is a potent and selective inhibitor of HPK1 extracted from patent WO2018049200A1, compound 50. HPK1-IN-15 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer. Synonyms: N-(3-fluorobenzyl)-6-(2-hydroxy-5-nitrobenzylidene)-4-pyrimidinamine. CAS No. 2201098-03-3. Molecular formula: C24H21ClF3N5. Mole weight: 471.91. | |
| HPK1-IN-16 | HPK1-IN-16 is a potent and selective inhibitor of HPK1 extracted from patent WO2019051199A1, compound 39. HPK1-IN-16 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer. CAS No. 2294965-95-8. Molecular formula: C28H27FN4O. Mole weight: 454.54. | |
| HPK1-IN-17 | HPK1-IN-17 is a potent and selective inhibitor of HPK1 extracted from patent WO2019238067A1, compound 73. HPK1-IN-17 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer. CAS No. 2403600-07-5. Molecular formula: C26H28N6O. Mole weight: 440.54. | |
| HPK1-IN-18 | HPK1-IN-18 is a potent and selective inhibitor of HPK1 extracted from patent WO2019238067A1, compound 1. HPK1-IN-18 is useful in researching, preventing or ameliorating diseases or disorders associated with HPK1 activity such as cancer. CAS No. 2403598-42-3. Molecular formula: C24H24N4. Mole weight: 368.47. | |
| HPK1-IN-19 | HPK1-IN-19 is a potent and selective inhibitor of HPK1 extracted from patent WO2018102366A1 compound I-47. CAS No. 2227609-33-6. Molecular formula: C27H32N7O2P. Mole weight: 517.56. | |
| HPK1-IN-2 | HPK1-IN-2 is an orally active inhibitor of hematopoietic progenitor kinase-1 (HPK1), Lck and Flt3 with IC50 of <0.05 μM, <0.5 μM and <0.05 μM, respectively. CAS No. 2056122-11-1. Molecular formula: C19H20N6OS. Mole weight: 380.47. | |
| HPK1-IN-20 | HPK1-IN-20 is a hematopoietic progenitor kinase 1 (HPK1) inhibitor extracted from patent WO2020235902A1 compound 106. CAS No. 2561490-78-4. Molecular formula: C26H28N6O2. Mole weight: 456.54. | |
| HPK1-IN-3 | HPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC50 of 0.25 nM. Synonyms: HPK1-IN-3; 4-[2-fluoro-6-(trifluoromethyl)anilino]-2-[(6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino]pyrimidine-5-carboxamide; CHEMBL4878586; BDBM552521; WO2022098809, Example 4-8; MS-29115; HY-138568; CS-0159070; 4-((2-fluoro-6-(trifluoromethyl)phenyl)amino)-2-((6-methoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-7-yl)amino)pyrimidine-5-carboxamide; YK1. Grade: 98%. Molecular formula: C23H22F4N6O2. Mole weight: 490.45. | |
| HPK1-IN-3 | HPK1-IN-3 is a potent and selective ATP-competitive hematopoietic progenitor kinase 1 (HPK1; MAP4K1) inhibitor with an IC50 of 0.25 nM. HPK1-IN-3 has IL-2 cellular potency with an EC50 of 108 nM in human peripheral blood mononuclear cells (PBMCs)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2739844-34-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-138568. |  |
| HPK1-IN-32 | HPK1-IN-32 is a potent and selective HPK1 inhibitor with an IC50 of 65 nM. HPK1-IN-32 can be used for the research of HPK1 related disorders or diseases[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2766481-17-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148847. | |
| HPK1-IN-34 | HPK1-IN-34 (Compound 143) is a Hematopoietic progenitor kinase 1 (HPK1) inhibitor with an IC50 of <100 nM[1]. HPK1-IN-34 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups. Uses: Scientific research. Category: Signaling pathways. CAS No. 2380300-99-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153362. | |
| HPK1-IN-4 | HPK1-IN-4 is a HPK1 (MAPK41) inhibitor with an IC50 of 0.061 nM. Synonyms: HPK1-IN-4; 2739844-28-9; CHEMBL4865305; EX-A5129; BDBM50569672; AKOS040758005; MS-27782; HY-138569; CS-0159071. Grade: 99%. CAS No. 2739844-28-9. Molecular formula: C23H26N6O3. Mole weight: 434.49. | |
| HPK1-IN-7 | HPK1-IN-7 is a potent, orally active HPK1 inhibitor with excellent family and kinome selectivity. HPK1-IN-7 shows selectivity against IRAK4 (59 nM) and GLK (140 nM). Synonyms: (S)-5-((4-((2-Hydroxy-1-phenylethyl)amino)-5-(1,3,4-oxadiazol-2-yl)pyrimidin-2-yl)amino)-3,3-dimethylisobenzofuran-1(3H)-one. Grade: 99%. CAS No. 2320462-65-3. Molecular formula: C24H22N6O4. Mole weight: 458.48. | |
| HPK1-IN-8 | HPK1-IN-8 is an allosteric, inactive conformation-selective inhibitor of full-length HPK1. CAS No. 1214561-09-7. Molecular formula: C19H17FN6O2S. Mole weight: 412.44. | |
| HPLC Analysis of Cholesterol-Lowering Drugs (Statins) on Discovery Cyano | HPLC Analysis of Cholesterol-Lowering Drugs (Statins) on Discovery Cyano. Product ID: ACMA00005296. Alfa Chemistry - ISO 9001:32057 Certified. |  |
| HPMC | Hydroxypropyl methylcellulose (HPMC) is a semisynthetic, inert, viscoelastic polymer of cellulose. Cellulose is alkali-treated then reacted with propylene oxide and methyl chloride to produce hydroxypropyl methylcellulose. Hydroxypropyl substitution increases water solubility, thermal gelation and film-forming properties. HPMC is non-ionic and displays reversible thermal gelation. HPMC can have a low, medium or high viscosity based on molecular weight and degree of substitution. Applications: Applications of hpmc include its use as a binder, disintegrant and controlled release matrix component of tablets in the pharmaceutical industry; it is also used in vegetarian capsules and solutions for eye medications. used as an ingredient in construction materials such as tile adhesive and self-leveling cement, it imparts water retention, workability, and adhesion characteristics. it is used in the food industry as a thickener/emulsifier/stabilizer in sauces, baked goods and meat substitutes. hpmc can also be used in cosmetics as a viscosity control agent and film former for shampoo, lotion, and makeup. Category: Cellulose series. CAS No. 9004-65-3. Product ID: PIE-0230. Appearance: White powder. |  |
| HPMC (Type II,Viscosity:100000mPa.s) | HPMC (Hypromellose; (Hydroxypropyl)methyl cellulose; Celacol HPM 5000) (Type II,Viscosity:100000mPa.s) is a non-ionic polymer obtained via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, including the diffusion of drugs in the hydrated matrix and the polymer relaxation process[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Type II,Viscosity:100000mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:100000mPa.s); Celacol HPM 5000 (Type II,Viscosity:100000mPa.s). CAS No. 9004-65-3. Pack Sizes: 100 g; 500 g; 1 k g. Product ID: HY-A0104I. | |
| HPMC (Type II,Viscosity:3mPa.s) | HPMC (Type II, Viscosity: 3 mPa.s) is a nonionic polymer prepared via synthetic modification of cellulose. As a hydrophilic matrix material, HPMC prolongs drug release through non-Fickian diffusion, which includes the diffusion of drugs in the hydrated matrix and the polymer relaxation process[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Type II,Viscosity:3mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:3mPa.s); Celacol HPM 5000 (Type II,Viscosity:3mPa.s). CAS No. 9004-65-3. Pack Sizes: 500 mg; 1 g; 5 g. Product ID: HY-A0104K. | |
| HPMC (Type II,Viscosity:5mPa.s) | HPMC (Hypromellose) (Type II,Viscosity:5mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. HPMC (Type II,Viscosity:5mPa.s) is widely used in agent formulations due to its biocompatibility, uncharged nature, solubility in water and thermoplastic behavior[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Type II,Viscosity:5mPa.s); (Hydroxypropyl)methyl cellulose (Type II,Viscosity:5mPa.s); Celacol HPM 5000 (Type II,Viscosity:5mPa.s). CAS No. 9004-65-3. Pack Sizes: 1 g; 5 g; 10 g. Product ID: HY-A0104J. | |
| HPMC (Type I,Viscosity:30mPa.s) | Hydroxypropylmethylcellulose (Type I,Viscosity:30mPa.s) is a biochemical reagent that can be used as a biological material or organic compound for life science related research. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Type I,Viscosity:30mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:30mPa.s); Celacol HPM 5000 (Type I,Viscosity:30mPa.s). CAS No. 9004-65-3. Pack Sizes: 1 g; 5 g; 10 g; 25 g; 50 g. Product ID: HY-A0104A. | |
| HPMC (Type I,Viscosity:4000mPa.s) | HPMC (Hypromellose) (Type I, Viscosity: 4000mPa.s) is a primary sodium alginate and controlled release hydrophilic polymer with an average viscosity of 4000mPa.s. The viscosity of HPMC may change due to concentration, pH, temperature or the presence of metal ions. When the pH is above 10, the viscosity decreases[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Type I,Viscosity:4000mPa.s); (Hydroxypropyl)methyl cellulose (Type I,Viscosity:4000mPa.s); Celacol HPM 5000 (Type I,Viscosity:4000mPa.s). CAS No. 9004-65-3. Pack Sizes: 5 g; 10 g. Product ID: HY-A0104D. | |
| HPMC (Viscosity:11250-21000mPa.s) | HPMC (Viscosity:11250-21000mPa.s) is a hydrophilic, non-ionic cellulose ether used to form swellable-soluble matrices. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Hypromellose (Viscosity:11250-21000mPa.s); (Hydroxypropyl)methyl cellulose (Viscosity:11250-21000mPa.s); Celacol HPM 5000 (Viscosity:11250-21000mPa.s). CAS No. 9004-65-3. Pack Sizes: 500 mg; 1 g. Product ID: HY-A0104. | |
| HPN-01 | HPN-01 is a potent and selective IKK inhibitor, with pIC50 values of 6.4, 7.0 and <4.8 for IKK-α, IKK-β and IKK-ε, respectively. HPN-01 displays greater 50-fold selectivity over a panel of more than 50 other kinases, including ALK5, CDK-2, EGFR, ErbB2, GSK3β, PLK1, Src, and VEGFR-2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 928655-63-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-135366. | |
| HPN-01 | HPN-01 is a potent and selective inhibitor of IKK, with pIC50s of 6.4, 7.0 and <4.8 for IKK-α, IKK-β and IKK-ε, respectively. It shows greater 50-fold selectivity over a panel of more than 50 other kinases, including ALK5, CDK-2, EGFR, ErbB2, GSK3β, PLK1, Src and VEGFR-2. Synonyms: [1,1':3',1''-Terphenyl]-5'-carboxamide, 4'-amino-4''-(aminosulfonyl)-4-chloro-; 4'-Amino-4-chloro-4''-sulfamoyl-1,1':3',1''-terphenyl-5'-carboxamide; 2-Amino-3-(4-sulfamoylphenyl)-5-(4-chlorophenyl)benzamide; 4'-amino-4-chloro-4''-sulfamoyl-[1,1'; 3',1'']terphenyl-5'-carboxylic acid amide. Grade: ≥98%. CAS No. 928655-63-4. Molecular formula: C19H16ClN3O3S. Mole weight: 401.87. | |
| HP-NH2 | CD Bioparticles provides HP-NH2, Heparins for drug delivery. Group: Heparins. |  |
| HPOB | HPOB is a potent, selective HDAC6 inhibitor with IC50 of 56 nM, >30-fold selectivity over other HDACs. Synonyms: 4-[(Hydroxyamino)carbonyl]-N-(2-hydroxyethyl)-N-phenylbenzeneacetamide. Grade: >98%. CAS No. 1429651-50-2. Molecular formula: C17H18N2O4. Mole weight: 314.34. | |
| HPP854 | HPP854, developed by High Point Pharmaceuticals, is a small molecule BACE1 protein inhibitor. Phase 1. Synonyms: HPP854; TTP-854. | |
| HPPD-IN-3 | HPPD-IN-3 (compound 25) is a potent inhibitor of 4-Hydroxyphenylpyruvate dioxygenase (HPPD), with IC50 of 10 nM, more potency than Mesotrione (HY-12853)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3024245-46-0. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-161308. | |
| HPPE | HPPE (compound 236) is an orally active, potential Bach1 inhibitor. Bach1 is a transcription factor of the cap'n'collar type alkaline region leucine zipper factor family (CNC-bZip) that regulates mitochondrial metabolism and reduces glucose utilization. HPPE can be used for research in psoriasis, multiple sclerosis, and COPD[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Bach1-IN-1. CAS No. 1325721-55-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-153040. | |
| HPPH | HPPH. Pack Sizes: Milligram Quantities: 50 mg. Order Number: I105. |  www.prochemonline.com |
| HPPH | HPPH (Photochlor) is a second generation photosensitizer, which acts as a photodynamic therapy (PDT) agent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Photochlor. CAS No. 149402-51-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-13722. | |
| H-p-Phenyl-D-Phenylalanine | H-p-Phenyl-D-Phenylalanine. Synonyms: D-Bip(4,4')-OH; H-p-Phenyl-D-Phe-OH; (R)-2-Amino-3-biphenyl-4-yl-propionic acid. Grade: ≥ 98% (TLC). CAS No. 170080-13-4. Molecular formula: C15H15NO2. Mole weight: 241.29. | |
| H-p-Phenyl-D-Phenylalanine | H-p-Phenyl-D-Phenylalanine. Group: Biochemicals. Alternative Names: D-Bip(4,4')-OH; H-p-Phenyl-D-Phe-OH; (R)-2-Amino-3-biphenyl-4-yl-propionic acid. Grades: Highly Purified. CAS No. 170080-13-4. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. US Biological Life Sciences. |  Worldwide |
| H-p-Phenyl-D-Phenylalanine 98+% (TLC) | H-p-Phenyl-D-Phenylalanine 98+% (TLC). Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g, 10g. US Biological Life Sciences. | Worldwide |
| H-p-Phenyl-L-Phenylalanine | H-p-Phenyl-L-Phenylalanine. Group: Biochemicals. Alternative Names: L-Bip(4,4')-OH; H-L-Ala(4,4'-biphenyl)-OH; (S)-2-Amino-3-biphenyl-4-yl-propionic acid. Grades: Highly Purified. CAS No. 155760-02-4. Pack Sizes: 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| H-p-Phenyl-L-Phenylalanine | H-p-Phenyl-L-Phenylalanine. Synonyms: L-Bip(4,4')-OH; H-L-Ala(4,4'-biphenyl)-OH; (S)-2-Amino-3-biphenyl-4-yl-propionic acid. Grade: ≥ 99.0% (HPLC). CAS No. 155760-02-4. Molecular formula: C15H15NO2. Mole weight: 241.29. | |
| H-p-Phenyl-L-Phenylalanine 99+% | H-p-Phenyl-L-Phenylalanine 99+%. Group: Biochemicals. Grades: Reagent Grade. Pack Sizes: 250mg, 1g, 5g. US Biological Life Sciences. | Worldwide |
| H-Pro-2-Chlorotrityl Resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. | |
| H-Pro-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: L-Proline-2-chlorotrityl resin. |  |
| H-Pro-AMC | H-Pro-AMC. Synonyms: (S)-N-(4-Methyl-2-oxo-2H-chromen-7-yl)pyrrolidine-2-carboxamide. CAS No. 96643-94-6. Molecular formula: C15H16N2O3. Mole weight: 272.30. | |
| H-Pro-Arg-AMC. 2 HCl | H-Pro-Arg-AMC is a fluorogenic Plasmodium falciparum dipeptidyl aminopeptidase 1 (DPAP1, cathepsin C) substrate. Synonyms: H-Pro-Arg-AMC. 2 HCl. Grade: 95%. CAS No. 546103-85-9. Molecular formula: C21H28N6O4. Mole weight: 428.49. | |
| H-Pro-Asn-OH | Prolyl-Asparagine is a dipeptide composed of proline and asparagine. Synonyms: Pro-Asn; H-Pro-Asn-OH; L-prolyl-L-asparagine. CAS No. 107856-82-6. Molecular formula: C9H15N3O4. Mole weight: 229.23. | |
| H-PRO-ASP-OH | H-PRO-ASP-OH. Synonyms: Pro-Asp; L-prolyl-L-aspartic acid; Prolyl-Aspartate; prolyl-aspartic acid; L-Pro-L-Asp; (S)-2-[((S)-Pyrrolidine-2-carbonyl)-amino]-succinic acid. Grade: >99%. CAS No. 85227-98-1. Molecular formula: C9H14N2O5. Mole weight: 230.22. | |
| H-Pro-Gly-Pro-OH | H-Pro-Gly-Pro-OH is a collagen-derived matrikine that has classically been described as a neutrophil chemoattractant. H-Pro-Gly-Pro-OH is perfectly positioned to focus neutrophils on the site required and direct a localized repair response. H-Pro-Gly-Pro-OH activates the transcription of neurotrophins and their receptor genes after cerebral ischemia[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Pro-Gly-Pro. CAS No. 7561-51-5. Pack Sizes: 5 mg; 10 mg. Product ID: HY-P4486. | |
| H-Pro-Gly-Pro-OH | H-Pro-Gly-Pro-OH (PGP), a tripeptide produced by the breakdown of extracellular matrix collagen, has specific chemotactic effects on neutrophils in vitro and in vivo. Ac-PGP generated by N-terminal acetylation of PGP can enhance this chemotactic potential. PGP is a physiological substrate for the activity of leukotriene A4 hydrolase aminopeptidase, and a biomarker for chronic obstructive pulmonary disease (COPD). Synonyms: H-PGP-OH; L-prolyl-glycyl-L-proline; L-Proline, L-prolylglycyl-; prolyl-glycyl-proline. Grade: ≥95% by HPLC. CAS No. 7561-51-5. Molecular formula: C12H19N3O4. Mole weight: 269.30. | |
| H-Pro-Hyp-OH | H-Pro-Hyp-OH is a collagen peptide composed of proline (Pro) and hydroxyproline (Hyp). H-Pro-Hyp-OH can be used in research on slowing down facial aging[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Prolylhydroxyproline; Pro-Hyp. CAS No. 18684-24-7. Pack Sizes: 10 mM * 1 mL in DMSO; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W337672. | |
| H-Pro-Ile-OH | H-Pro-Ile-OH is a derivative of isoleucine, an α-amino acid that is used in the biosynthesis of proteins. Synonyms: Pro-ile; Prolylisoleucine; l-prolyl-l-isoleucine; N-L-Prolyl-L-isoleucine; L-Pro-L-Ile-OH. CAS No. 51926-51-3. Molecular formula: C11H20N2O3. Mole weight: 228.29. | |
| H-PRO-LEU-GLY-NHOH HCL | An affinity ligand for the purification of human collagenases. Synonyms: Pro-Leu-Gly hydroxamate hydrochloride. Grade: 95%. CAS No. 120928-08-7. Molecular formula: C13H25ClN4O4. Mole weight: 336.82. | |
| H-PRO-LEU-OH | H-PRO-LEU-OH. Synonyms: Pro-leu; L-prolyl-L-leucine; (S)-4-Methyl-2-((S)-pyrrolidine-2-carboxamido)pentanoic acid. CAS No. 52899-07-7. Molecular formula: C11H20N2O3. Mole weight: 228.29. | |
| H-Pro-Met-OH | H-Pro-Met-OH is used as an antihypertensive drug or health care product. Synonyms: L-Prolyl-L-methionine; Pro-Met; prolylmethionine; PM dipeptide; Proline Methionine dipeptide. Grade: >99%. CAS No. 52899-08-8. Molecular formula: C10H18N2O3S. Mole weight: 246.33. | |
| H-Pro-NH2 | An impurity of Vildagliptin. Vildagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that is used as an anti-hyperglycemic agent. Vildagliptin could reduce hyperglycemia in type 2 diabetes mellitus via the suppressive effect of inactivation of GLP-1 and GIP by DPP-4. Synonyms: L-Prolinamide; (2S)-2-Pyrrolidinecarboxamide; (-)-Prolinamide; (2S)-2-Carbamoylpyrrolidine; (2S)-Pyrrolidine-2-carboxylic acid amide; (S)-2-(Aminocarbonyl)pyrrolidine; (S)-Prolinamide; (S)-Proline Amide; 2-Pyrrolidinecarboxamide, (2S)-; 2-Pyrrolidinecarboxamide, (S)-; Prolinamide, L-; (S)-Pyrrolidine-2-carboxamide; (S)-Pyrrolidine-2-carboxylic acid amide; L-Proline amide. Grade: ≥95%. CAS No. 7531-52-4. Molecular formula: C5H10N2O. Mole weight: 114.10. | |
| H-Pro-pNA TFA | H-Pro-pNA TFA acts as a chromogenic substrate for prolyl aminopeptidase (proline iminopeptidase). Synonyms: L-Proline 4-nitroanilide trifluoroacetate; (S)-N-(4-Nitrophenyl)-2-pyrrolidinecarboxamide Mono(trifluoroacetate); (2S)-N-(4-Nitrophenyl)-2-pyrrolidinecarboxamide Mono(trifluoroacetate); H-L-Pro-pNA Trifluoracetate; H-Pro-Pna TFA; L-Proline p-nitroanilide trifluoroacetate salt; Pro-pNA; P-pNA; H Pro Pna TFA; 2-Pyrrolidinecarboxamide, N-(4-nitrophenyl)-, (2S)-, mono(trifluoroacetate); 2-Pyrrolidinecarboxamide, N-(4-nitrophenyl)-, (S)-, mono(trifluoroacetate); 2-Pyrrolidinecarboxamide, N-(4-nitrophenyl)-, (2S)-, 2,2,2-trifluoroacetate (1:1). Grade: ≥95%. CAS No. 108321-19-3. Molecular formula: C11H13N3O3.C2HO2F3. Mole weight: 349.26. | |
| H-Pro-Pro-Asp-NH2 | H-Pro-Pro-Asp-NH2, adsorbed on modified silica gel, is a highly efficient recyclable chiral catalyst for aldol reactions. Synonyms: H-PPD-NH2; L-prolyl-L-prolyl-L-isoasparagine; L-Prolyl-L-prolyl-L-α-asparagine; (S)-4-amino-4-oxo-3-((S)-1-((S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)butanoic acid. Grade: ≥95%. CAS No. 850440-85-6. Molecular formula: C14H22N4O5. Mole weight: 326.35. | |
| H-Pro-Pro-Gln-OH | H-Pro-Pro-Gln-OH is an effective catalyst for conjugate addition reaction between aldehydes and β-substituted nitroolefins. Synonyms: H-PPQ-OH; L-prolyl-L-prolyl-L-glutamine; Prolyl-prolyl-glutamine; (S)-5-amino-5-oxo-2-((S)-1-((S)-pyrrolidine-2-carbonyl)pyrrolidine-2-carboxamido)pentanoic acid. Grade: ≥95%. CAS No. 856170-98-4. Molecular formula: C15H24N4O5. Mole weight: 340.37. | |
| H-PRO-PRO-PRO-PRO-OH | PPPP was used as an internal standard in the quantitative determination of the antihypertensive (ACE-inhibiting) peptides IPP and VPP in cheese by HPLC-MS3. Synonyms: L-Pro-Pro-Pro-Pro. CAS No. 21866-90-0. Molecular formula: C20H30N4O5. Mole weight: 406.48. | |
| H-Pro-Pro-Ser(OtBu)-NH2 | H-Pro-Pro-Ser(OtBu)-NH2 is a protected tripeptide used in peptide synthesis. The H indicates a free N-terminus on the proline (Pro) residue, allowing for further coupling or reactions. The sequence includes two proline residues, which are known for introducing structural kinks or turns in peptide chains. The hydroxyl group of the serine (Ser) residue is protected by an OtBu (tert-butyl) group, which prevents it from reacting until selective deprotection. The -NH2 at the C-terminus denotes a free amine group, enabling additional modifications or coupling reactions. This peptide is utilized to introduce proline and serine into peptide sequences while controlling functional group reactivity through selective protection. Synonyms: PPS; (S)-1-(L-Prolyl)-N-((S)-1-amino-3-(tert-butoxy)-1-oxopropan-2-yl)pyrrolidine-2-carboxamide; H-Pro-Pro-Ser(tBu)-NH2. Grade: ≥95%. Molecular formula: C17H30N4O4. Mole weight: 354.45. | |
| H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH | H-Pro-Thr-Glu-Phe-p-nitro-Phe-Arg-Leu-OH, the p-nitrophenylalanine-containing substrate, is used for a convenient assay of pepsin and other aspartic proteinases of animal and microbial origin. It is soluble over a wide pH range with the Km values showing only little variation (Km = 80 μM at pH 3.1 and 37°C for porcine pepsin). Synonyms: L-prolyl-L-threonyl-L-alpha-glutamyl-L-phenylalanyl-4-nitro-L-phenylalanyl-L-arginyl-L-leucine; PTEF-Nph-RL; L-Pro-L-Thr-L-Glu-L-Phe-4-Nitro-L-Phe-L-Arg-L-Leu-OH; (2S,5S,8S,11S,14S)-11-benzyl-5-(3-guanidinopropyl)-14-((2S,3R)-3-hydroxy-2-((S)-pyrrolidine-2-carboxamido)butanamido)-2-isobutyl-8-(4-nitrobenzyl)-4,7,10,13-tetraoxo-3,6,9,12-tetraazaheptadecane-1,17-dioic acid; L-Leucine, N-(N2-(4-nitro-N-(N-(N-(N-L-prolyl-L-threonyl)-L-alpha-glutamyl)-L-phenylalanyl)-L-phenylalanyl)-L-arginyl)-, (2'E)-; L-Prolyl-L-threonyl-L-α-glutamyl-L-phenylalanyl-4-nitro-L-phenylalanyl-N5-(diaminomethylene)-L-ornithyl-L-leucine. Grade: ≥95%. CAS No. 90331-82-1. Molecular formula: C44H63N11O13. Mole weight: 954.04. | |
| HPTDP | HPTDP. Synonyms: HPTDP; S-(1-Oxo-2-pyridyl)-thio-1,3-dimethylpropyleneuronium hexafluorophosphate; S-(1-Oxo-2-pyridyl)-thio-1,3-dimethylpropyleneuronium hexafluorophosphate; 1,3,5-Trimethyl-2-[(1-oxo-1lambda~5~-pyridin-2-yl)sulfanyl]-4,5-dihydro-1H-imidazol-3-ium hexafluorophosphate. Grade: 97% (HPLC). CAS No. 366821-62-7. Molecular formula: C11H16N3OS.PF6. Mole weight: 383.29. | |
| hPTHrP (1-36) | hPTHrP (1-36) has been shown to be one of the authentic secretory forms of PTHrP. Synonyms: Parathyroid hormone-related protein (1-36); Ala-Val-Ser-Glu-His-Gln-Leu-Leu-His-Asp-Lys-Gly-Lys-Ser-Ile-Gln-Asp-Leu-Arg-Arg-Arg-Phe-Phe-Leu-His-His-Leu-Ile-Ala-Glu-Ile-His-Thr-Ala-Glu-Ile. CAS No. 172867-62-8. Molecular formula: C191H305N59O52. Mole weight: 4260.10. | |
| HPTU | HPTU. Synonyms: HPTU; 1,1,3,3-Tetramethyl-2-(2-oxopyridin-1(2H)-yl)isouronium hexafluorophosphate; 1,1,3,3-Tetramethyl-2-(2-oxopyridin-1(2H)-yl)isouroniumhexafluorophosphate; AmbotzRL-1092; M-1123; O-(2-pyridone)-1,1,3,3-tetramethyluronium hexafluorophosphate; O-(1,2-dihydro-2-oxo-pyridyl)-N,N,N',N'-tetramethyluronium hexafluorophosphate. Grade: 95%. CAS No. 364047-51-8. Molecular formula: C10H16N3O2.F6P. Mole weight: 355.22. | |
| HPTU | HPTU. Group: Biochemicals. Alternative Names: 1,1,3,3-Tetramethyl-2-(2-oxopyridin-1(2H)-yl)isouronium hexafluorophosphate. Grades: Highly Purified. CAS No. 364047-51-8. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. Molecular Formula: C10H16F6N3O2P. US Biological Life Sciences. | Worldwide |
| HPV16-E711-20 epitope | HPV16-E711-20 epitope is a known HLA-A*0201-restricted human cytotoxic T lymphocyte (CTL) epitope of HPV16-E7 protein, which binds to HLA-A2 with high affinity in vitro. Synonyms: H-Tyr-Met-Leu-Asp-Leu-Gln-Pro-Glu-Thr-Thr-OH; L-tyrosyl-L-methionyl-L-leucyl-L-alpha-aspartyl-L-leucyl-L-glutaminyl-L-prolyl-L-alpha-glutamyl-L-threonyl-L-threonine. Grade: ≥95%. CAS No. 160040-04-0. Molecular formula: C53H83N11O19S. Mole weight: 1210.35. | |
| HPV16 E7 86-93 | HPV16 E7 86-93 is a human leukocyte antigen (HLA)-A2-restricted HPV16 E7 derived peptide that has immunogenicity in cervical cancer. Synonyms: H-Thr-Leu-Gly-Ile-Val-Cys-Pro-Ile-OH; L-threonyl-L-leucyl-glycyl-L-isoleucyl-L-valyl-L-cysteinyl-L-prolyl-L-isoleucine. Grade: ≥95%. CAS No. 160212-93-1. Molecular formula: C37H66N8O10S. Mole weight: 815.03. | |
| HPV16 E7 (86-93) acetate | HPV16 E7 86-93 is a human leukocyte antigen (HLA)-A2-restricted HPV16 E7 derived peptide that has immunogenicity in cervical cancer. Synonyms: HPV16 E7 (86-93) acetate; AKOS040764039. Molecular formula: C39H70N8O12S. Mole weight: 875.08. | |
| H-Pyr-OBzl | H-Pyr-OBzl. Grade: ≥ 95%. Molecular formula: C12H13NO3. Mole weight: 219.2. | |
| H-Pyr-Oet HCl | H-Pyr-Oet HCl. Synonyms: ethyl (2S)-5-oxopyrrolidine-2-carboxylate hydrochloride. CAS No. 105210-68-2. Molecular formula: C7H11NO3·HCl. Mole weight: 193.7. | |
| HpySE526 I | One unit of the enzyme is the amount required to hydrolyze 1 μg of pUC19 DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 5-fold overdigestion with enzyme about 95% of the dna fragments can be ligated with t4 dna ligase and recut. Group: Restriction Enzymes. Purity: 200U; 1000U. A↑CGT TGC↓A. Activity: 5000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain, that carries the cloned HpySE 526I gene from Helicobacter pylori SE526. Pack: 10 mM Tris-HCl (pH 7.6); 100 mM NaCl; 0,1 mM EDTA; 200 μg/ml BSA; 1 mM DTT; and 50% glycerol. Cat No: ET-1123RE. |  |
| HQ005 | HQ005 is a potent CCNK degrader with an DC50 value of 0.041 μM. HQ005 is a molecular-glue degrader that mediates interactions between target proteins and components of the ubiquitin-proteasome system to cause selective protein degradation[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2750644-31-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-148523. | |
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