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| Product | Description | |
|---|---|---|
| HRO761 | HRO761 (Werner syndrome RecQ helicase-IN-1) (example 42) is a potent Werner syndrome RecQ DNA helicase enzyme (WRN) inhibitor and can be used in cancer research[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Werner syndrome RecQ helicase-IN-1. CAS No. 2869954-34-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 1 g. Product ID: HY-148699. |  |
| HRO761 | HRO761 is a potent, selective, allosteric inhibitor of Werner syndrome RecQ helicase (WRN). It binds at the interface of the D1 and D2 helicase domains, locking WRN in an inactive conformation, and demonstrates anti-proliferative effects specifically in microsatellite instability (MSI) cancer cells. Group: Inhibitors. CAS No. 2869954-34-5. Pack Sizes: 5mg. Product ID: E1908. Formula: C31H31ClF3N9O5. |  United States; Europe |
| HRS-4642 | HRS-4642 is a high affinity, selective, long-acting, and non-covalent KRASG12D inhibitor with a Kd value of 0.083 nM. HRS-4642 inhibits the binding of KRASG12D to SOS1 or RAF1, thereby blocking the downstream MEK-ERK signaling pathway. HRS-4642 promotes Apoptosis. HRS-4642 alone or combined with Carfilzomib (HY-10455) effectively shapes the tumor microenvironment. HRS-4642 has an anti-cancer effect on pancreatic and colorectal cancers carrying the KRASG12D mutation[1][2][3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2836263-09-1. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159127. | |
| HRV3C Protease from human, Recombinant | Human rhinovirus 3C protease (HRV3C Protease) is a cysteine protease that recognizes the cleavage site of Leu-Glu-Val-Leu-Phe-Gln*Gly-Pro. It is supplied as a 47 kDa protein with both GST and Histidine tags for easy removal by His-Select or Glutathione agarose along with the cleaved tag. HRV3C Protease is capable of cleaving small peptides with the sequence of polyprotein processing sites. It cleaves after the glutamine residue. HRV cleavage site generally contains Gln/Gly scissile bond. Hrv3c protease is a recombinant restriction-grade cysteine protease. it folds into two topologically alike six-stranded β barrels. however, β barrels are different in length and. with both gst and histidine tags for easy removal by his-select or glutathione agarose along with the cleaved tag. hrv3c protease has a therapeutic implication because of its unique protein structure. it may be used for the biochemical and structural characterization conducted on hrv 3c protease along with the development of 3c protease inhibitors. Group: Enzymes. Synonyms: HRV3C Protease; HRV3C; Human rhinovirus 3C protease. HRV3C. Activity: > 1 units/μg. Storage: -20°C. Form: Supplied as a solution in 25 mM Tris-HCl, pH 8.0, 50 mM NaCl, 1 mM TCEP and 50% glycerol. Source: E. coli. Species: Human. HRV3C Protease; HRV3C; Human rhinovirus 3C protease. Cat No: NATE-0345. |  |
| HRV-3C protease fuses with GST | HRV-3C protease fuses with GST is a recombinant protease fused with HRV-3C protease and GST, which recognizes the LEVLFQGP polypeptide sequence. HRV-3C protease fuses with GST precisely cleaves between glutamine and glycine-proline residues to remove fusion tags from target proteins. HRV-3C protease fuses with GST exhibits cleavage activity both in vitro in silkworm fat body lysates and in vivo in silkworm larval fat bodies, and achieves functional expression in E. coli and silkworm-baculovirus expression systems. HRV-3C protease fuses with GST can be applied to recombinant protein-related research[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2178107-79-2. Pack Sizes: 500 μg; 1 mg. Product ID: HY-E70528. | |
| HRX-0233 | HRX-0233 is a small-molecule MAP2K4 inhibitor. HRX-0233 results in strong tumor shrinkage without any apparent toxicity in H358 KRASG12C-mutant non-small cell lung cancers (NSCLC) in vivo. HRX-0233 efficiently prevents feedback activation of receptor tyrosine kinases (RTKs) upon monotherapy KRAS inhibitor Sotorasib (HY-114277) and causes a more sustained and complete inhibition of MAPK signaling. HRX-0233 is promising for research of AR-negative prostate cancer, lung and colon cancers[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2409140-12-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-159190. | |
| HRX-0233 | HRX-0233 is a small molecule inhibitor targeting MAP2K4. In vivo, HRX-0233 effectively reduces tumors in H358 KRASG12C mutant non-small cell lung cancer (NSCLC) without significant toxicity. Category: Active pharmaceutical ingredients. CAS No. 2409140-12-9. Product ID: API2409140129. Molecular formula: C24H21F2N5O3S. Mole weight: 497.52. |  |
| HS 014 | HS 014. Group: Biochemicals. Grades: Purified. CAS No. 207678-81-7. Pack Sizes: 1mg. US Biological Life Sciences. |  Worldwide |
| HS 014 | HS 014 is a potent and selective melanocortin MC4 receptor antagonist (Ki = 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors, respectively). HS 014 promotes food intake in rats and nociception in mice following central administration in vivo. HS 014 also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus. Alternative Names: HS 014; HS014; HS-014. CAS No. 207678-81-7. Molecular formula: C71H94N20O17S2. Mole weight: 1563.77. |  |
| HS 014 acetate | HS 014 acetate is a potent and selective melanocortin MC4 receptor antagonist with Kis of 3.16, 108, 54.4 and 694 nM for cloned human MC4, MC1, MC3 and MC5 receptors, respectively. HS 014 promotes food intake in rats and nociception in mice following central administration in vivo. HS 014 also inhibits IL-1β-induced Fos expression in the paraventricular hypothalamus. Alternative Names: HS014 acetate; HS-014 acetate; Ac-Cys-Glu-His-D-2Nal-Arg-Trp-Gly-Cys-Pro-Pro-Lys-Asp-NH2.CH3CO2H (Disulfide bridge: Cys1-Cys8); N-acetyl-L-cysteinyl-L-alpha-glutamyl-L-histidyl-3-(2-naphthyl)-D-alanyl-L-arginyl-L-tryptophyl-glycyl-L-cysteinyl-L-prolyl-L-prolyl-L-lysyl-L-isoasparagine (1->8)-disulfide acetic acid. Grades: ≥95%. Molecular formula: C73H98N20O19S2. Mole weight: 1623.83. | |
| HS 024 | HS 024 is a potent melanocortin MC4 receptor antagonist (Ki = 0.29, 18.6, 5.45 and 3.29 nM for cloned human MC4, MC1, MC3 and MC5 receptors, respectively). HS 024 promotes food intake, blocks α-MSH- and MTII-induced hypotension and bradycardia in rats, following central administration in vivo. Alternative Names: Acetyl-(Cys3,Nle4,Arg5,D-2-Nal7,Cys11)-α-MSH (3-11) amide; N-acetyl-L-cysteinyl-L-norleucyl-L-arginyl-L-histidyl-3-(2-naphthyl)-D-alanyl-L-arginyl-L-tryptophyl-glycyl-L-cysteinamide (1->9)-disulfide; Ac-Cys(1)-Nle-Arg-His-D-2Nal-Arg-Trp-Gly-Cys(1)-NH2; HS024; HS-024. Grades: ≥95%. CAS No. 212370-59-7. Molecular formula: C58H79N19O10S2. Mole weight: 1266.52. | |
| HS 024 | HS 024. Group: Biochemicals. Grades: Purified. CAS No. 212370-59-7. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| HS-1371 | HS-1371 is a potent and ATP-competitive receptor-interacting protein kinase 3 (RIP3) inhibitor with an IC50 of 20.8 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2158197-70-5. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-114349. | |
| HS-173 | HS-173 is a potent and selective PI3Kα inhibitor displaying anticancer activity. HS-173 was shown to induce apoptosis via arresting the cell cycle at the G2/M phase. It also decreases angiogenesis induced by VEGF. Alternative Names: Ethyl 6-(5-(phenylsulfonamido)pyridin-3-yl)imidazo[1,2-a]pyridine-3-carboxylate; HS173; HS 173; HS-173. Grades: 98%. CAS No. 1276110-06-5. Molecular formula: C21H18N4O4S. Mole weight: 422.459. | |
| HS-276 | HS-276 is an orally active, potent and highly selective TAK1 inhibitor, with a Ki of 2.5 nM. HS-276 shows significant inhibition of TAK1, CLK2, GCK, ULK2, MAP4K5, IRAK1, NUAK, CSNK1G2, CAMKKβ-1, and MLK1, with IC50 values of 8.25, 29, 33, 63, 125, 264, 270, 810, 1280, and 5585 nM, respectively. HS-276 reduces the expression of TNF, IL-6, and IL-1β. HS-276 can be used for rheumatoid arthritis (RA) research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2767422-72-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-147141. | |
| HS38 | HS38 is a potent, selective, and ATP-competitive inhibitor of death-associated protein kinase 1 (DAPK1) and zipper-interacting protein kinase (ZIPK, also called DAPK3), with Kds of 300 nM and 280 nM, respectively. HS38 is also a PIM3 inhibitor with an IC50 of 200 nM. HS38 can be used for the research of smooth muscle related disorders[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1030203-81-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15847. | |
| Hs-AFP1 | HsAFP1 is a plant defensin isolated from the coral bell (Heuchera sanguinea), which has a broad-spectrum antifungal activity. Alternative Names: Asp-Gly-Val-Lys-Leu-Cys(1)-Asp-Val-Pro-Ser-Gly-Thr-Trp-Ser-Gly-His-Cys(2)-Gly-Ser-Ser-Ser-Lys-Cys(3)-Ser-Gln-Gln-Cys(4)-Lys-Asp-Arg-Glu-His-Phe-Ala-Tyr-Gly-Gly-Ala-Cys(2)-His-Tyr-Gln-Phe-Pro-Ser-Val-Lys-Cys(3)-Phe-Cys(4)-Lys-Arg-Gln-Cys(1). | |
| hsa-miR-146a-5p agomir | hsa-miR-146a-5p agomirs are chemically-modified double-strand miRNA mimics with modified mature miRNA strand: 2 phosphorothioates at the 5' end, 4 phosphorothioates at the 3' end, 3' end cholesterol group, and full-length nucleotide 2'-methoxy modification. Compared with miRNA mimics, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo. Grades: ≥90% by HPLC. Mole weight: 15104.36. | |
| hsa-miR-146a-5p antagomir | hsa-miR-146a-5p antagomirs are chemically-modified oligonucleotides that hybridize with mature miRNAs. The miRNA antagomirs strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Stability of miRNA antagomirs appears to be significantly higher than miRNA inhibitors, they exhibits enhanced cellular uptake, stability and regulatory activity in vivo. Grades: ≥90% by HPLC. Mole weight: 7311.74. | |
| hsa-miR-146a-5p Inhibitor | hsa-miR-146a-5p inhibitors are chemically-modified oligonucleotides that hybridize with mature miRNAs. hsa-miR-146a-5p inhibitors have full-length nucleotide 2'-methoxy modification. They strongly compete with mature miRNAs to prevent the complementary pairing of miRNAs and their target genes, thereby inhibiting miRNAs from functioning. Grades: ≥90% by HPLC. Mole weight: 6592.37. | |
| hsa-miR-146a-5p mimic | miRNA Mimics are chemically modified, double-stranded miRNA-like RNA which are designed to copy the functionality of mature endogenous miRNA upon transfection. This synthetic miRNA mimic is used to overexpress hsa-miR-146a-5p by transfection. Grades: ≥90% by HPLC. Mole weight: 13943.40. | |
| HsAp | HsAp is an antibacterial peptide isolated from Heterometrus spinifer. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Ser-Gly-Thr-Ser-Glu-Lys-Glu-Arg-Glu-Ser-Gly-Arg-Leu-Leu-Gly-Val-Val-Lys-Arg-Leu-Ile-Val-Cys-Phe-Arg-Ser-Pro-Phe-Pro. Grades: 95.9%. | |
| HsAp2 | HsAp2 is an antibacterial peptide isolated from Heterometrus spinifer. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Ser-Gly-Thr-Ser-Glu-Lys-Glu-Arg-Glu-Ser-Glu-Arg-Leu-Leu-Gly-Val-Val-Asn-Pro-Leu-Ile-Lys-Cys-Phe-Arg-Ser-Pro-Cys-Pro. Grades: 97.8%. | |
| HsAp3 | HsAp3 is an antibacterial peptide isolated from Heterometrus spinifer. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Ser-Gly-Thr-Pro-Glu-Lys-Glu-Arg-Glu-Ser-Gly-Arg-Leu-Leu-Gly-Val-Val-Lys-Arg-Tyr-Ile-Val-Cys-Val-Arg-Asn-Pro-Cys-Pro. Grades: 95.9%. | |
| HsAp4 | HsAp4 is an antibacterial peptide isolated from Heterometrus spinifer. It has activity against gram-positive bacteria, gram-negative bacteria and fungi. Alternative Names: Ser-Gly-Thr-Ser-Glu-Lys-Glu-Arg-Glu-Ser-Gly-Arg-Leu-Leu-Gly-Val-Val-Lys-Arg-Leu-Ile-Val-Gly-Phe-Arg-Ser-Pro-Phe-Arg. Grades: 95.5%. | |
| H-Sar-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: Sarcosine-2-chlorotrityl resin; N-Methyl-glycine-2-chlorotrityl resin. |  |
| H-Sar-OBzl TosOH | H-Sar-OBzl TosOH. Alternative Names: N-Me-Gly-Obzl P-Tosylate; Sarcosine benzyl ester 4-toluenesulfonate salt. Grades: ≥ 98% (Assay). CAS No. 54384-06-4. Molecular formula: C10H13NO2·C7H8O3S. Mole weight: 351.4. | |
| H-(S)-beta-Phe(3-F)-OH | H-(S)-beta-Phe(3-F)-OH. Alternative Names: L-β-Phe(3-F)-OH; (S)-3-Fluoro-β-phenylalanine; (S)-3-Amino-3-(3-fluorophenyl)propanoic acid; (3S)-3-amino-3-(3-fluorophenyl)propanoic acid. Grades: ≥ 95% (HPLC). CAS No. 723284-79-5. Molecular formula: C9H10FNO2. Mole weight: 183.19. | |
| H-(S)-beta-Phe-OH | (S)-β-Phenylalanine is a key building block used as an intermediate in the synthesis of pharmaceuticals. Alternative Names: (S)-3-Amino-3-phenylpropionic acid; Benzenepropanoic acid, β-amino-, (S)-; L-β-Phe-OH. Grades: ≥ 99% (HPLC). CAS No. 40856-44-8. Molecular formula: C9H11NO2. Mole weight: 165.19. | |
| H-(S)-beta-Tyr-OH | H-(S)-beta-Tyr-OH. Alternative Names: (S)-3-Amino-3-(4-hydroxyphenyl)propionic acid; H-b-Phe(4-OH)-OH; H-D-PHG(4-OH)-(CCH2)OH; L-β-Phe(4-OH)-OH; L-β-Tyr-OH. Grades: ≥ 98% (HPLC,Chiral purity). CAS No. 54732-46-6. Molecular formula: C9H11NO3. Mole weight: 181.19. | |
| HS-(CH2)11-PEG12-OH | HS-(CH2)11-PEG12-OH. | |
| H-Ser-AMC | H-Ser-AMC. Alternative Names: (2S)-2-amino-3-hydroxy-N-(4-methyl-2-oxochromen-7-yl)propanamide. CAS No. 98516-73-5. Molecular formula: C13H14N2O4. Mole weight: 262.27. | |
| H-SER-ASP-OH | H-Ser-Asp-OH is used in the preparation polypeptide compounds for enhancement of immune system. Alternative Names: Ser-Asp; serylaspartic acid; L-seryl-L-aspartic acid; SD dipeptide; Seryl-aspartic acid; Serine Aspartate dipeptide. CAS No. 2543-31-9. Molecular formula: C7H12N2O6. Mole weight: 220.18. | |
| H-Ser(Bzl)-OH HCl | H-Ser(Bzl)-OH HCl. Alternative Names: L-Serine, O-(phenylmethyl)-, hydrochloride; (S)-2-Amino-3-(benzyloxy)propanoic acid hydrochloride; L-Ser(Bzl)-OH HCl; O-Benzyl-L-serine Hydrochloride. CAS No. 76614-98-7. Molecular formula: C10H14ClNO3. Mole weight: 231.67. | |
| H-Ser-Gln-OH | H-Ser-Gln-OH. Alternative Names: Ser-Gln; Serinyl-Glutamine; L-seryl-L-glutamine; SQ dipeptide; L-Ser-L-Gln; Serine Glutamine dipeptide. CAS No. 94421-66-6. Molecular formula: C8H15N3O5. Mole weight: 233.22. | |
| H-Ser(HPO3Bzl)-2-Chlorotrityl Resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. | |
| H-Ser-Ile-Gly-Ser-Leu-Ala-Lys-OH | H-Ser-Ile-Gly-Ser-Leu-Ala-Lys-OH, a tryptic peptide originally isolated from E. coli, contains the active site of penicillin-binding protein 1b. Alternative Names: S-I-G-S-L-A-K; L-seryl-L-isoleucyl-glycyl-L-seryl-L-leucyl-L-alanyl-L-lysine; L-Lysine, L-seryl-L-isoleucylglycyl-L-seryl-L-leucyl-L-alanyl-; (2S,5S,8S,11S,17S,20S)-20-amino-2-(4-aminobutyl)-17-sec-butyl-21-hydroxy-11-(hydroxymethyl)-8-isobutyl-5-methyl-4,7,10,13,16,19-hexaoxo-3,6,9,12,15,18-hexaazahenicosan-1-oic acid. Grades: 95%. CAS No. 115918-58-6. Molecular formula: C29H54N8O10. Mole weight: 674.79. | |
| H-Serinol(Bzl) | A reagent used in the synthesis of β-amino alcohols, which are biological compounds for medical use. Alternative Names: (R)-2-Amino-3-(benzyloxy)propan-1-ol; O-benzyl-L-serinol. Grades: ≥ 98% (HPLC). CAS No. 58577-87-0. Molecular formula: C10H15NO2. Mole weight: 181.23. | |
| H-Ser-Leu-Ser-Leu-Ser-Pro-Gly-OH | H-Ser-Leu-Ser-Leu-Ser-Pro-Gly-OH, a peptide from the C-terminus of the human Ig Gamma-1 chain C region, is used for structural characterization of recombinant hybrid IgG molecules by MS analysis of tryptic digests. Alternative Names: L-seryl-L-leucyl-L-seryl-L-leucyl-L-seryl-L-prolyl-glycine. Grades: ≥95%. CAS No. 943235-75-4. Molecular formula: C28H49N7O11. Mole weight: 659.74. | |
| H-Ser-OBzl hydrochloride | H-Ser-OBzl hydrochloride. Alternative Names: DL-Ser-Obzl HCl; (3-hydroxy-1-oxo-1-phenylmethoxypropan-2-yl)azanium chloride. CAS No. 879278-55-4. Molecular formula: C10H14ClNO3. Mole weight: 231.67. | |
| H-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-Ile-Aib-Leu-OMe | H-Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-Ile-Aib-Leu-OMe is a protected heptapeptide used in peptide synthesis. It consists of serine (Ser), aspartic acid (Asp), tyrosine (Tyr), and isoleucine (Ile), along with α-aminoisobutyric acid (Aib) and leucine (Leu), with OtBu (tert-butyl) groups protecting the hydroxyl groups of serine, aspartic acid, and tyrosine. The peptide ends with a methyl ester (OMe) group at the C-terminus, allowing for further modifications or coupling. This peptide is designed for controlled reactivity and stability, and is useful in applications such as peptide synthesis, drug design, and functional studies of peptide interactions. Alternative Names: Ser(OtBu)-Asp(OtBu)-Tyr(OtBu)-Ser(OtBu)-Ile-Aib-Leu-OMe; Methyl (2-((2S,3S)-2-((S)-2-((S)-2-((S)-2-((S)-2-amino-3-(tert-butoxy)propanamido)-4-(tert-butoxy)-4-oxobutanamido)-3-(4-(tert-butoxy)phenyl)propanamido)-3-(tert-butoxy)propanamido)-3-methylpentanamido)-2-methylpropanoyl)-L-leucinate; H-Ser(tBu)-Asp(tBu)-Tyr(tBu)-Ser(tBu)-Ile-Aib-Leu-OMe. Grades: ≥98%. Molecular formula: C52H89N7O13. Mole weight: 1020.32. | |
| H-Ser(OtBu)-Ser(OtBu)-Gly-OMe | H-Ser(OtBu)-Ser(OtBu)-Gly-OMe is a protected tripeptide used in peptide synthesis. The H indicates a free N-terminus on the serine (Ser) residue, allowing for further coupling or reactions. The hydroxyl groups on both serine residues are protected by OtBu (tert-butyl) groups, which prevent these groups from reacting until deprotection is carried out. Gly (Glycine), the final amino acid in the sequence, is followed by an OMe (methyl ester) group at the C-terminus, which indicates that the carboxyl group of glycine is esterified. This esterification can help in controlling reactivity or facilitating further modifications. This compound is used to introduce serine and glycine into peptides with specific protections to ensure controlled and efficient peptide synthesis. Alternative Names: SSG; Ser(tBu)-Ser(tBu)-Gly-OMe; Methyl O-(tert-butyl)-N-(O-(tert-butyl)-L-seryl)-L-serylglycinate. Grades: ≥95%. Molecular formula: C17H33N3O6. Mole weight: 375.47. | |
| H-Ser-Ser-OH | H-Ser-Ser-OH. Alternative Names: L-seryl-L-serine; Ser-Ser; Ser Ser. CAS No. 6620-95-7. Molecular formula: C6H12N2O5. Mole weight: 192.17. | |
| H-Ser(tBu)-2-Chlorotrityl Resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. | |
| H-Ser(tBu)-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: O-t-Butyl-L-serine-2-chlorotrityl resin. | |
| H-Ser(tBu)-ol-2-chlorotrityl resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. Alternative Names: H-Ser(tBu)-ol-Trt(2-Cl)-Resin; H-Ser(tBu)-ol-Barlos Resin; O-(t-Butyl)-L-serinol 2-chlorotrityl resin. | |
| H-Ser(Trt)-2-Chlorotrityl Resin | 2-Chlorotrityl-Chloride-Resin is less acid-labile than Trityl Resin, and is widely used for solid phase immobilization. It has been used with the Fmoc/tBu methodology in the microwave-assisted solid phase peptide synthesis. | |
| H-Ser(Trt)-2-Cl-Trt Resin | Alfa Chemistry's amino acid 2-Cl-Trt resins are available in loadings ranging from 0.4 to 0.7 mmol/g. Since the linked amino acids are N-protected, these resins can be used without pretreatment. Alternative Names: O-Trityl-L-serine-2-chlorotrityl resin. | |
| H-Ser-Tyr-AMC | H-Ser-Tyr-AMC. Alternative Names: SER-TYR-AMC; SER-TYR-7-AMINO-4-METHYLCOUMARIN; L-SERYL-L-TYROSINE 7-AMIDO-4-METHYLCOUMARIN; H-SER-TYR-AMC. CAS No. 201855-53-0. Molecular formula: C22H23N3O6. Mole weight: 425.43. | |
| H-SER-TYR-OH | H-SER-TYR-OH. Alternative Names: Ser-Tyr; L-seryl-L-tyrosine; Serinyltyrosine; SY dipeptide; L-Ser-L-Tyr; Serine Tyrosine dipeptide. CAS No. 21435-27-8. Molecular formula: C12H16N2O5. Mole weight: 268.27. | |
| HSF1A | HSF1A is a cell-permeable activator of heat shock transcription factor 1 (HSF1)[1]. HSF1A also acts as a specific inhibitor of TRiC/CCT. Chaperonin TCP-1 ring complex (TRiC)/chaperonin containing TCP-1 (CCT) plays a pivotal role in toxin translocation and/or refolding[4]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1196723-93-9. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-103000. | |
| HSG-75, Electrically conductive heat sink grease, Ag ?75% | HSG-75, Electrically conductive heat sink grease, Ag ?75%. | |
| HSG, Heat sink grease | HSG, Heat sink grease. | |
| HSGN-94 | HSGN-94 is a potent antimicrobial agent with lipoteichoic acid (LTA) biosynthesis inhibition. HSGN-94 inhibits drug-resistant Gram-positive bacteria with MIC values of 0.25-2 μg/mL. HSGN-94 inhibits biofilm formation of MRSA and Vancomycin-resistant Enterococci. HSGN-94 also inhibits pro-inflammatory cytokines, exhibits in vivo efficacy in an MRSA murine wound infection model[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2570797-85-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-146811. | |
| HSL-IN-1 | HSL-IN-1 (compound 24b) is a potent and orally active hormone sensitive lipase (HSL) inhibitor (IC50=2 nM) with a significantly reduced reactive metabolite liability[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2095156-13-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-101509. | |
| HSL-IN-5 | HSL-IN-5 (Example 21) is a hormone sensitive lipase (HSL) inhibitor (IC50: 0.25 μM). HSL-IN-5 can be used for diabetes research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 308830-70-8. Pack Sizes: 5 mg; 10 mg; 25 mg. Product ID: HY-164714. | |
| HslU-HslV peptidase | The HslU subunit of the HslU-HslV complex functions as an ATP dependent 'unfoldase'. The binding of ATP and its subsequent hydrolysis by HslU are essential for unfolding of protein substrates subsequently hydrolysed by HslV. HslU recognizes the N-terminal part of its protein substrates and unfolds these before they are guided to HslV for hydrolysis. In peptidase family T1. Group: Enzymes. Synonyms: HslUV; HslV-HslU; HslV peptidase; ATP-dependent HslV-HslU proteinase; caseinolytic protease X; caseinolytic proteinase X; ClpXP ATP-dependent protease; ClpXP protease; ClpXP serine proteinase; Escherichia coli ClpXP serine proteinase; HslUV protease; HslUV proteinase; HslVU protease; HslVU proteinase; protease HslVU; proteinase HslUV. Enzyme Commission Number: EC 3.4.25.2. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4375; HslU-HslV peptidase; EC 3.4.25.2; HslUV; HslV-HslU; HslV peptidase; ATP-dependent HslV-HslU proteinase; caseinolytic protease X; caseinolytic proteinase X; ClpXP ATP-dependent protease; ClpXP protease; ClpXP serine proteinase; Escherichia coli ClpXP serine proteinase; HslUV protease; HslUV proteinase; HslVU protease; HslVU proteinase; protease HslVU; proteinase HslUV. Cat No: EXWM-4375. | |
| hSMG-1 inhibitor 11e | hSMG-1 inhibitor 11e is a potent and selective hSMG-1 kinase inhibitor with an IC50 of <0.05 nM. hSMG-1 inhibitor 11e shows>900-fold selectivity over mTOR (IC50 of 45 nM), PI3Kα/γ (IC50s of 61 nM and 92 nM) and CDK1/CDK2 (IC50s of 32 μM and 7.1 μM)[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1402452-10-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124760. | |
| hSMG-1 inhibitor 11j | hSMG-1 inhibitor 11j, a pyrimidine derivative, is a potent and selective inhibitor of hSMG-1, with an IC50 of 0.11 nM. hSMG-1 inhibitor 11j exhibits >455-fold selectivity for hSMG-1 over mTOR (IC50=50 nM), PI3Kα/γ (IC50=92/60 nM) and CDK1/CDK2 (IC50=32/7.1 μM). hSMG-1 inhibitor 11j can be used for the research of cancer[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1402452-15-6. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124719. | |
| HSP27 inhibitor J2 | HSP27 inhibitor J2 (J2) is a HSP27 inhibitor, which significantly induces abnormal HSP27 dimer formation and inhibits a production of HSP27 giant polymers, thereby having an effect of inhibiting a chaperone function of the HSP27 and reducing a cell protection function thereof. HSP27 inhibitor J2 (J2) remarkably enhances the antiproliferative activity of 17-AAG and sensitizes cisplatin-induced lung cancer cell growth inhibition[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: J2. CAS No. 2133499-85-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124653. | |
| HSP60 Antibody [G1B22] | Heat Shock Protein 60,HSP 60,HSP60. Group: Antibodies. Alternative Names: Heat Shock Protein 60,HSP60. Pack Sizes: 20uL. Product ID: F0482. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Hsp70 Antibody [C13L16] | Heat Shock Protein 70,HSP 70,Hsp70. Group: Antibodies. Alternative Names: Heat Shock Protein 70,Hsp70. Pack Sizes: 20uL. Product ID: F1607. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| Hsp70-derived octapeptide | Hsp70-derived octapeptide is a C-terminal conserved octapeptide of HSP70 that interacts with the motif of tetratricopeptide repeat (TPR). Alternative Names: H-Gly-Pro-Thr-Ile-Glu-Glu-Val-Asp-OH; glycyl-L-prolyl-L-threonyl-L-isoleucyl-L-alpha-glutamyl-L-alpha-glutamyl-L-valyl-L-aspartic acid. Grades: ≥95%. CAS No. 736171-62-3. Molecular formula: C36H58N8O16. Mole weight: 858.89. | |
| HSP90 Antibody [L2G2] | Heat Shock Protein 90,HSP90,HSP90 alpha / beta. Group: Antibodies. Alternative Names: Heat Shock Protein 90,HSP90,HSP90 alpha / beta. Pack Sizes: 20uL. Product ID: F0283. Storage Conditions: -20°C (avoid freeze-thaw cycles), 2 years. | United States; Europe |
| HSP90-IN-23 | HSP90-IN-23 (Comp 12-1) is an inhibitor of heat shock protein 90(HSP90) with an IC50 of 9 nM. HSP90-IN-23 induces apoptosis of tumor cells and arrests the tumor cell cycle in G0/G1 phase. HSP90-IN-23 can be used for cancer research[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 2944100-30-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-149891. | |
| HSP990 | HSP990 is an orally bioavailable inhibitor of human heat-shock protein 90 (HSP90) with potential antineoplastic activity. HSP990 binds to and inhibits the activity of Hsp90, which may result in the proteasomal degradation of oncogenic client proteins, including HER2/ERBB2, and the inhibition of tumor cell proliferation. HSP90, upregulated in a variety of tumor cells, is a molecular chaperone that plays a key role in the conformational maturation, stability and function of oncogenic signaling proteins, such as HER2/ERBB2, AKT, RAF1, BCR-ABL, and mutated p53, as well as many other molecules that are important in cell cycle regulation and/or immune responses. Alternative Names: NVP-HSP990; NVP HSP990; NVPHSP990; HSP 990; HSP-990. Grades: >98%. CAS No. 934343-74-5. Molecular formula: C20H18FN5O2. Mole weight: 379.39. | |
| HspA I | One unit of the enzyme is the amount required to hydrolyze 1 μg of Lambda DNA in 1 hour at 37°C in a total reaction volume of 50 μl. Applications: After 20-fold overdigestion with enzyme more than 90% of the dna fragments can be ligated and recut. Group: Restriction Enzymes. Purity: 1000U; 5000U. G↑CGC CGC↓G. Activity: 20000u.a./ml. Appearance: 10 X SE-buffer Y. Storage: -20°C. Form: Liquid. Source: An E.coli strain that carries the cloned HspA I gene from Haemophilus species A1. Pack: 10 mM Tris-HCl (pH 7.5); 50 mM NaCl; 0.1 mM EDTA; 7 mM 2-mercaptoethanol; 200 μg/ml BSA; 50% glycerol. Cat No: ET-1124RE. | |
| HSPC | HSPC. Pack Sizes: 1 g. Product ID: PE-0353. Category: Lipid Excipients. Product Keywords: Pharmaceutical Excipients; Lipid Excipients; HSPC; PE-0353. Purity: ≥99%. Application: Liposome and Micelle Formulations in Market. Product Description: L-α-phosphatidylcholine, hydro genated (Soy). |  |
| HS-PEG1500-SH | Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Alternative Names: HS-PEG-SH, Thiol-PEG-Thiol. Mole weight: average Mn 1,500. | |
| HS-PEG2K-NH2 | Polyethylene glycol (PEG) compounds contain a polyether unit, commonly expressed as R1-(O-CH2-CH2)n-O-R2. They are generally biocompatible, non-toxic and stable in both organic and aqueous solutions, and so are extensively used in biological applications, as well as nanotechnology and materials research. Proteins with PEG chain modifications and compounds encapsulated in PEG liposomes exhibit a longer half-life in vivo than their non-PEGylated counterparts, a phenomenon known as PEG shielding. Functionalised PEG lipids and phospholipids can be used for protein-PEG conjugation. Alternative Names: HS-PEG-NH2. Mole weight: average Mn 2000. | |
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