A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Iota-Carratetraitol-Tetrasulfate Tetrasodium Salt is an extraordinary biomedical compound, used for studying drug-resistant bacteria, with a special emphasis on eradicating skin and soft tissue infections. Alternative Names: Ι-Carratetraitol-Tetrasulfate Tetrasodium Salt. Grades: ≥98% by GPC. Molecular formula: C24H36O30S4Na4. Mole weight: 1024.74.
Iota-Carratetraose-Tetrasulfate Tetrasodium Salt
Iota-Carratetraose-Tetrasulfate Tetrasodium Salt is an auspicious biomedical compound with anti-inflammatory attributes, adeptly intercepting explicit receptors and signaling cascades. It is used for studying inflammation linked with afflictions encompassing arthritis, asthma and inflammatory bowel disease. Alternative Names: Ι-Carratetraose-Tetrasulfate Tetrasodium Salt. Grades: ≥98% by GPC. Molecular formula: C24H34O29S4Na4. Mole weight: 1006.73.
iota-Cyclodextrin
iota-Cyclodextrin is a versatile substance extensively utilized in the biomedical sector, exhibiting remarkable potential as a pharmaceutical transporter. By amplifying the solubility and stability of diverse compounds, it functions as an efficacious drug delivery compound. Empowered by its ability to form inclusion complexes, it proficiently enwraps hydrophobic compounds, thereby facilitating the research of ailments such as cancer, diabetes and cardiovascular disorders. Alternative Names: Cyclomaltotetradecaose; CD14. CAS No. 156510-94-0. Molecular formula: C84H140O70. Mole weight: 2269.97.
Iotalamic acid
Lotalamic acid (Iothalamic acid) is a contrast agent. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Iothalamic acid. CAS No. 2276-90-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1053.
Iothalamate Sodium
Iothalamate sodium is an ionic, high-osmolar, tri-iodinated radiographic contrast agent used primarily for urography, angiography, and computed tomography enhancement. It is available as a sterile solution for intravascular, intracavitary, or intrathecal administration, though its use has largely been replaced by low-osmolar and iso-osmolar agents. The compound contains three iodine atoms per molecule, providing excellent radiopacity. Applications: It is indicated for various radiographic procedures including intravenous urography, peripheral arteriography, coronary arteriography, and contrast-enhanced computed tomography. it is also used to measure glomerular filtration rate clinically, as its renal clearance closely approximates inulin clearance. due to the risk of contrast-induced nephropathy and hypersensitivity reactions, including anaphylaxis, its use requires careful patient selection, particularly in those with pre-existing renal impairment or contrast allergy. Category: Other apis. Synonyms: Sodium iothalamate; Angio-Conray; Mediocontrix; Iothalamic acid sodium salt; KDN276D83N; DTXSID1057668; Monosodium 5-acetamido-2,4,6-triiodo-N-methylisophthalamate. CAS No. 1225-20-3. Product ID: API0231564. Molecular formula: C11H8I3N2NaO4. Mole weight: 635.89. EINECS: 214-955-8. InChIKey: WCIMWHNSWLLELS-UHFFFAOYSA-M.
Iothalamic Acid
Iothalamic Acid. Group: Biochemicals. Alternative Names: 3- (Acetylamino) -2, 4, 6-triiodo-5-[ (methylamino) carbonyl]benzoic Acid; 5-Acetamido-2,4,6-triiodo-N-methylisophthalamic Acid; 5-Acetylamino-2,4,6-triiodo-N-methyl-3-isophthalamic Acid; Cysto Conray II; Iotalamic Acid; MI 216; Methalamic Acid. Grades: Highly Purified. CAS No. 2276-90-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Iotrolan
Iotrolan is a non-ionic, dimeric iodinated contrast medium specifically designed for myelography and cisternography. Unlike conventional intravascular contrast agents, it is formulated for intrathecal use and is characterized by high hydrophilicity, low protein binding, and minimal neurotoxicity. Applications: Used in diagnostic myelography and cisternography for imaging the spinal canal and subarachnoid space. iotrolan is a non-ionic dimeric contrast agent specifically formulated for intrathecal use with high hydrophilicity, near-zero protein binding, and minimal neurotoxicity, providing superior safety for neuroradiological procedures. Category: Active pharmaceutical ingredients. Synonyms: 5,5'-[(1,3-Dioxo-1,3-propanediyl)bis(methylimino)]bis[N,N'-bis[2,3-dihydroxy-1-(hydroxymethyl)propyl]-2,4,6-triiodo-1,3-benzenedicarboxamide];2,4,6-triiodo-5-[methyl-[Chemicalbook3-[methyl-[2,4,6-triiodo-3,5-bis(1,3,4-trihydroxybutan-2-ylcarbamoyl)phenyl]amino]-3-oxo-propanoyl]amino]-N1,N3-bis(1,3,4-trihydroxybutan-2-yl)benzene-1,3-dicarboxamide. CAS No. 79770-24-4. Product ID: API79770244. Molecular formula: C37H48I6N6O18. Mole weight: 1626.2. InChIKey: XUHXFSYUBXNTHU-UHFFFAOYSA-N.
Ioversol
Nonionic, low osmolality, radiographic contrast agent. Diagnostic aid (radiopaque medium). Group: Biochemicals. Alternative Names: N,N'-bis(2,3-dihydroxypropyl)-5-[(hydroxyacetyl)(2-hydroxyethyl)amino]-2. Grades: Highly Purified. CAS No. 87771-40-2. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ioversol
Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MP-328. CAS No. 87771-40-2. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-B1410.
Ioversol Impurity 1
Ioversol Impurity 1. Uses: For analytical and research use. CAS No. 2061892-21-3. Molecular formula: C20H28I3N3O10. Mole weight: 851.17. Catalog: APB2061892213.
Ioversol impurity 10
Ioversol impurity 10. Uses: For analytical and research use. Molecular formula: C24H24Cl4I3N3O11. Mole weight: 1052.98. Catalog: APB12236.
Ioversol impurity 11
Ioversol impurity 11. Uses: For analytical and research use. Molecular formula: C24H24Cl5I2N3O11. Mole weight: 961.52. Catalog: APB12237.
Ioversol impurity 12
Ioversol impurity 12. Uses: For analytical and research use. CAS No. 134768-85-7. Molecular formula: C15H18I3N3O7. Mole weight: 733.04. Catalog: APB134768857.
Ioversol impurity 13
Ioversol impurity 13. Uses: For analytical and research use. CAS No. 196309-13-4. Molecular formula: C18H22IN3O9. Mole weight: 551.29. Catalog: APB196309134.
Ioversol impurity 14
Ioversol impurity 14. Uses: For analytical and research use. Molecular formula: C18H24ClI2N3O9. Mole weight: 715.66. Catalog: APB12239.
Ioversol impurity 15
Ioversol impurity 15. Uses: For analytical and research use. CAS No. 872117-56-1. Molecular formula: C11H12I3N3O4. Mole weight: 630.95. Catalog: APB872117561.
Ioversol impurity 16
Ioversol impurity 16. Uses: For analytical and research use. Molecular formula: C26H30I3N3O12. Mole weight: 957.25. Catalog: APB12238.
Ioversol impurity 17
Ioversol impurity 17. Uses: For analytical and research use. CAS No. 2253945-67-2. Molecular formula: C16H22I3N3O7. Mole weight: 749.08. Catalog: APB2253945672.
Ioversol impurity 2
Ioversol impurity 2. Uses: For analytical and research use. Molecular formula: C20H28I3N3O10. Mole weight: 851.17. Catalog: APB12232.
Ioversol impurity 3
Ioversol impurity 3. Uses: For analytical and research use. CAS No. 77868-40-7. Molecular formula: C16H20I3N3O8. Mole weight: 763.06. Catalog: APB77868407.
Ioversol impurity 4
Ioversol impurity 4. Uses: For analytical and research use. CAS No. 69232-66-2. Molecular formula: C16H22I3N3O6. Mole weight: 733.08. Catalog: APB69232662.
Ioversol impurity 5
Ioversol impurity 5. Uses: For analytical and research use. CAS No. 78314-12-2. Molecular formula: C12H6Cl2I3NO5. Mole weight: 695.8. Catalog: APB78314122.
Ioversol impurity 6
Ioversol impurity 6. Uses: For analytical and research use. Molecular formula: C17H20I3N3O9. Mole weight: 791.07. Catalog: APB12234.
Ioversol impurity 7
Ioversol impurity 7. Uses: For analytical and research use. Molecular formula: C22H22Cl4I3N3O10. Mole weight: 1010.94. Catalog: APB12233.
Ioversol impurity 8
Ioversol impurity 8. Uses: For analytical and research use. CAS No. 155887-14-2. Molecular formula: C24H23Cl5I3N3O11. Mole weight: 1087.42. Catalog: APB155887142.
Ioversol impurity 9
Ioversol impurity 9. Uses: For analytical and research use. Molecular formula: C22H22Cl4I3N3O10. Mole weight: 1010.94. Catalog: APB12235.
Ioversol Related Compound A
Ioversol Related Compound A. Uses: For analytical and research use. CAS No. 76801-93-9. Mole weight: 705.02. Catalog: AP76801939-B.
Ioversol related compound B
An analog of Ioversol, which has been used as a contrast medium. Alternative Names: N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[2-(2-hydroxyethylamino)-2-oxoethoxy]isophthalamide; N,N'-Bis(2,3-dihydroxypropyl)-5-[(N-(2-hydroxyethyl)-carbamoyl)methoxy]-2,4,6-triiodoisophthalamide. Grades: 95 %. CAS No. 104517-96-6. Molecular formula: C18H24I3N3O9. Mole weight: 807.1.
Ioversol Related Compound B
Ioversol Related Compound B. Uses: For analytical and research use. CAS No. 104517-96-6. Mole weight: 807.11. Catalog: AP104517966.
IOX1
IOX1, a chemical probe, is a potent broad?spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 μM, 2.3 μM, 1.8 μM, 0.1 μM and 1.4 μM, respectively[1][2]. IOX1 also inhibits ALKBH5[3]. Uses: Scientific research. Category: Signaling pathways. CAS No. 5852-78-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 50 mg. Product ID: HY-12304.
IOX2
IOX2, a chemical probe, is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 931398-72-0. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15468.
IOX4
IOX4 is a selective HIF prolyl-hydroxylase 2 (PHD2) inhibitor with an IC50 value of 1.6 nM, induces HIFα in cells and in wildtype mice with marked induction in the brain tissue. IOX4 competes with and displaces 2-oxoglutarate (2OG) at the active site of PHD2[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1154097-71-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-120110.
Ioxaglate Meglumine
Ioxaglate Meglumine is an ionic, dimeric iodinated X-ray contrast medium. As a low-osmolality ionic dimer, it occupies a unique position between conventional ionic monomers and non-ionic dimers in the contrast agent spectrum, combining ionic dissociation with a reduced particle-to-iodine ratio. Applications: Used in diagnostic imaging for angiography, urography, and computed tomography (ct). ioxaglate meglumine is a low-osmolality ionic dimeric contrast agent that offers reduced osmotic stress compared to conventional ionic monomers while maintaining ionic dissociation characteristics for optimal radiographic density. Category: Active pharmaceutical ingredients. Synonyms: MEGLUMINE IOXAGLATE. CAS No. 59018-13-2. Product ID: API59018132. Molecular formula: C31H38I6N6O13. Mole weight: 1464.1. InChIKey: HUHDYASLFWQVOL-WZTVWXICSA-N.
Ioxilan
Ioxilan. Group: Biochemicals. Alternative Names: 5-[Acetyl(2,3-dihydroxypropyl)amino]-N1-(2,3-dihydroxypropyl)-N3-(2-hydroxyethyl)-2,4,6-triiodo-1,3-benzenedicarboxamide. Grades: Highly Purified. CAS No. 107793-72-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C18H24I3N3O8. US Biological Life Sciences.
Worldwide
Ioxitalamic Acid
A substituted 2,4,6-triiodobenzoic acid, an excellent contrast media for ventriculography, radiculography, lumbar myelography and x-rays of the cardiovascular system. Group: Biochemicals. Alternative Names: 3- (Acetylamino) -5-[[ (2-hydroxyethyl) amino]carbonyl]-2, 4, 6-triiodobenzoic Acid;3-Acetamido-2,4,6-triiodo-(N- β -hydroxyethyl) isophthalic Acid Monoamide; AG 58107; Ioxitalamate. Grades: Highly Purified. CAS No. 28179-44-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
IP3(1,3,4) ammonium salt
IP3(1,3,4) ammonium salt is a chemical which occurs naturally in carbachol-stimulated rat parotid glands. Ins(1,3,4)P3 inhibits Ins(3,4,5,6)P4 1-kinase which regulates Ins(3,4,5,6)P4 levels. Alternative Names: D-Myo-inositol-1,3,4-triphosphate (ammonium salt); D-myo-Inositol, 1,3,4-tris(dihydrogen phosphate), ammonium salt (1:3). Grades: >97%. CAS No. 1246355-66-7. Molecular formula: C6H24N3O15P3. Mole weight: 471.19.
IP3RPEP6
IP3RPEP6 is an IP3R competitive inhibitor. IP3RPEP6 has the IC50 values of 9.0 μM, 3.9 μM and 4.3 μM for IP3R1, IP3R2 and IP3R3, respectively. IP3RPEP6 does not affect the Ryanodine receptor and Cx43 hemichannels. IP3RPEP6 regulates calcium signaling within cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 3061802-23-8. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P10849.
Ip5I
Ip5I is an anatagonist of P2X1/P2X3 receptor. Alternative Names: P1, P5- Di- (inosine- 5')- pentaphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1294478-76-4. Molecular formula: C20H27N8O24P5 (free acid). Mole weight: 918.3 (free acid).
IP7e
IP7e is a potent, brain-penetrant and orally active Nurr1 activator with an EC50 value of 3.9 nM[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 500164-74-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110274.
IPA 3
IPA 3. Group: Biochemicals. Grades: Purified. CAS No. 42521-82-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IPA 3
IPA 3. CAS No: 42521-82-4
Sarchem Laboratories New Jersey NJ
IPA-3
IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6). Uses: Scientific research. Category: Signaling pathways. CAS No. 42521-82-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15663.
IPA-99%
IPA-99%. Market: Industrial Additives, Cosmetics & Personal Care. Other names: Isopropal Alcohol, Isopropanol. PK Chem Industries: We supply chemicals related to Cosmetic, Personal Care, Food, Pharmaceutical, Feed, Agriculture and Mining Industries.
iPAF1C
iPAF1C is a inhibitor of the polymerase-associated factor 1 complex (PAF1C) with specific targeting to the PAF1 binding groove of CTR9 (a key subunit of PAF1C). iPAF1C disrupts PAF1C assembly by interfering with the PAF1-CTR9 interaction. iPAF1C selectively impairs BRD4-mediated recruitment of PAF1 to chromatin at hypoxia-responsive genes and inhibits RNA polymerase II (RNAPII) pause release. iPAF1C increases the population of HIV-1 NL4.3 Nef-IRES-GFP infected primary human CD4+T cells in a dose-dependent manner. PAF1C can be used for the study of infection and diseases associated with abnormal hypoxic adaptation (e.g., cancers, neurological disorders)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 950403-60-8. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160267.
Ipafricept
Ipafricept (OMP-54F28; FZD8-Fc) is a first class recombinant fusion protein with the extracellular part of the human frizzled-8 receptor fused to a human IgG1 Fc fragment that binds Wnt ligands, which blocks Wnt signaling. Ipafricept reduces tumor growth and results in a decrease in both liver and lung metastases combined with Gemcitabine (HY-17026) in pancreatic cancer mouse models. Ipafricept shows solid tumor inhibition activity with well tolerance, such as desmoid tumor, germ cell cancer, ovarian cancer[1][2][3]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: OMP-54F28; FZD8-Fc. CAS No. 1391727-24-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99667.
IPAG
IPAG. Group: Biochemicals. Grades: Purified. CAS No. 193527-91-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IPAM (Indole 3-propionamide)
A cell-permeable indole derivative that acts as an antioxidant and mitochondrial metabolism modifier. IPAM binds to the rate-limiting component of oxidative phosphorylation in complex I of the respiratory chain and acts as a stabilizer of energy metabolism, thereby reducing the production of reactive oxygen species (ROS). Group: Biochemicals. Alternative Names: Indole 3-propionamide. Grades: Highly Purified. CAS No. 5814-93-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ipatasertib
Ipatasertib, also known as GDC-0068 is an orally bioavailable inhibitor of the serine / threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GDC-0068 binds to and inhibits the activity of Akt in a non-ATP-competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Uses: Antineoplastic agents. Alternative Names: GDC-0068; GDC0068; GDC 0068; RG7440; RG-7440; RG 7440; Ipatasertib. CAS No. 1001264-89-6. Molecular formula: C24H32ClN5O2. Mole weight: 458.0.
Ipatasertib
Ipatasertib (GDC-0068) is an orally active, highly selective and ATP-competitive pan-Akt inhibitor with IC50 values of 5, 18, 8 nM for Akt1/2/3, respectively. Ipatasertib synchronously activates FoxO3a and NF-κB through inhibition of Akt leading to p53-independent activation of PUMA. Ipatasertib also induces apoptosis in cancer cells and inhibits tumor growth in xenograft mouse models[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-0068; RG7440. CAS No. 1001264-89-6. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15186.
Ipatasertib dihydrochloride
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: GDC-0068 dihydrochloride; RG-7440 dihydrochloride. CAS No. 1396257-94-5. Pack Sizes: 10 mM * 1 mL in DMSO; 2 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15186A.
Ipatasertib (GDC-0068)
Ipatasertib (GDC-0068, RG7440) is a highly selective pan-Akt inhibitor targeting Akt1/2/3 with IC50 of 5 nM/18 nM/8 nM in cell-free assays, 620-fold selectivity over PKA. Phase 2. Group: Inhibitors. Alternative Names: RG7440. CAS No. 1001264-89-6. Pack Sizes: 5mg. Product ID: S2808. Formula: C24H32ClN5O2. Smiles: CC1CC(C2=C1C(=NC=N2)N3CCN(CC3)C(=O)C(CNC(C)C)C4=CC=C(C=C4)Cl)O. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Ipatasertib impurity 1
Ipatasertib impurity 1. Uses: For analytical and research use. CAS No. 1001382-14-4. Molecular formula: C21H26ClN5O2. Mole weight: 415.92. Catalog: APB1001382144.
Iperoxo
Iperoxo is a potent superagonist of muscarinic acetylcholine receptor (mAChR) that activates M1, M2 and M3 receptors with pEC50 of 9.87, 10.1 and 9.78. Iperoxo can be used for direct probing activation-related conformational transitions of muscarinic receptors when labeled with tritium[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 247079-84-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-122743.
Ipflufenoquin
Ipflufenoquin is a fungicide being developed by Nippon-Soda Co. Ltd (Japan) which has stable efficacy against a wide range of plant diseases, such as gray mold, scab and rice blast. Alternative Names: 2-(2-((7,8-Difluoro-2-methyl-3-quinolyl)oxy)-6-fluorophenyl)propan-2-ol; 2-[(7,8-Difluoro-2-methyl-3-quinolinyl)oxy]-6-fluoro-α,α-dimethylbenzenemethanol. CAS No. 1314008-27-9. Molecular formula: C19H16F3NO2. Mole weight: 347.33.
Ipflufenoquin
Ipflufenoquin is an insecticide with the potential to control primary infection with apple scab. Ipflufenoquin should be applied between half an inch of green and fruit set[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1314008-27-9. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-134338.
IPI-549
IPI-549, a dihydroisoquinolin derivative, has been found to be a phosphatidylinositol 3 kinase gamma inhibitor, could exhibit antineoplastic activity in solid tumors. It is still under Phase I trial. IC50: 16 nM (PI3Kγ), 3.2 μM (PI3Kα), 3.5 μM (PI3Kβ), >8.4 μM (PI3Kδ). Alternative Names: Eganelisib; IPI 549; IPI549; 2-Amino-N-[(1S)-1-[1,2-dihydro-8-[2-(1-methyl-1H-pyrazol-4-yl)ethynyl]-1-oxo-2-phenyl-3-isoquinolinyl]ethyl]pyrazolo[1,5-a]pyrimidine-3-carboxamide; (S)-2-Amino-N-(1-(8-((1-methyl-1H-pyrazol-4-yl)ethynyl)-1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide. Grades: 98%. CAS No. 1693758-51-8. Molecular formula: C30H24N8O2. Mole weight: 528.58.
IPI-9119
IPI-9119 is an orally active, selective and irreversible FASN inhibitor with an IC50 of 0.3 nM in vitro biochemical assay. IPI-9119 inhibits tumor growth of castration-resistant prostate cancer (CRPC) xenografts mouse models[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1346564-56-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124628.
Ipidacrine is a drug used for the treatment of memory disorders. It acts as a reversible acetylcholinesterase inhibitor. Alternative Names: Senita; 2,3,5,6,7,8-hexahydro-1H-cyclopenta[b]quinolin-9-amine hydrochloride hydrate. CAS No. 118499-70-0. Molecular formula: C12H16N2.HCl.H2O. Mole weight: 242.75.
Ipilimumab
Ipilimumab binds to CTLA4 expressed on T-cells and inhibits the CTLA4-mediated downregulation of T-cell activation. This leads to a cytotoxic T-lymphocyte (CTL)-mediated immune response against cancer cells. Alternative Names: BMS-734016; MDX-010; BMS 734016; MDX 010; BMS734016; MDX010. CAS No. 477202-00-9. Molecular formula: C6742H9972N1732O2004S40.
Ipilimumab is a fully human monoclonal antibody IgG1κ that blocks the inhibitory receptor cytotoxic T lymphocyte antigen 4 (CTLA-4) on T cells. Ipilimumab can be used in unresectable or metastatic melanoma (MM) studies[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MDX-010; BMS-734016. CAS No. 477202-00-9. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg. Product ID: HY-P9901.
Ipilimumab (anti-CTLA-4)
Ipilimumab (anti-CTLA-4) is an immunomodulatory monoclonal antibody directed against the cell surface antigen CTLA-4 and also a type of immune checkpoint inhibitor. MW : 148 kD. Group: Antibodies. Alternative Names: MDX-010, BMS-734016. CAS No. 477202-00-9. Pack Sizes: 5mg. Product ID: A2001. Storage Conditions: Store the undiluted solution at 4°C in the dark to avoid freeze-thaw cycles.
United States; Europe
Ipilimumab impurity 1
Ipilimumab impurity 1. Uses: For analytical and research use. CAS No. 691007-05-3. Molecular formula: C12H14F2N2O. Mole weight: 240.25. Catalog: APB691007053.
Ipilimumab impurity 2
Ipilimumab impurity 2. Uses: For analytical and research use. CAS No. 1016743-93-3. Molecular formula: C12H13F2NO. Mole weight: 225.24. Catalog: APB1016743933.
Ipivivint
Ipivivint (Compound 38) is an orally active and potent CDC-like kinase (CLK) inhibitor with EC50 of 1 nM and 7 nM for CLK2 (human) and CLK3 (human), respectively. Ipivivint also inhibits the Wnt pathway (EC50=13 nM) and tyrosine phosphorylation-regulated kinase 1A (human) (EC50=5 nM)[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1481617-15-5. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-137443.
IPN60090
IPN-60090 is an orally active and highly selective inhibitor of glutaminase 1 (GLS1; IC50=31 nM), with no activity observed against GLS-2. IPN-60090 exhibits excellent physicochemical and pharmacokinetic properties in vivo. IPN-60090 can be used for solid tumors research, such as lung and ovarian cancers[1][2]. Uses: Scientific research. Category: Signaling pathways. CAS No. 1853164-83-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-103671.
IPO 8
It is an organophosphate cholinesterase inhibitor that is used as an insecticide. Alternative Names: Phosphoric acid, 2-chloro-1-(2,4,5-trichlorophenyl)ethenyl dimethyl ester; Benzyl alcohol, 2,4,5-trichloro-α-(chloromethylene)-, dimethyl phosphate; Phosphoric acid, 2-chloro-1-(2,4,5-trichlorophenyl)vinyl dimethyl ester; 2-Chloro-1-(2,4,5-trichlorophenyl)vinyl dimethyl phosphate; Dimethyl 2,4,5-trichloro-α-(chloromethylene)benzyl phosphate; Dimethyl-1-(2,4,5-trichlorophenyl)-2-chlorovinyl phosphate; Tetrachlorvinphos. CAS No. 961-11-5. Molecular formula: C10H9Cl4O4P. Mole weight: 365.96.