A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
Iridium(III) chloride (hydrate) (Iridium trichloride (hydrate)) is a biochemical reagent. Iridium(III) can be used in the research of colon cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: Iridium trichloride hydrate. CAS No. 14996-61-3. Pack Sizes: 100 mg; 250 mg; 500 mg; 1 g. Product ID: HY-W021022.
Iridium trinitrate. CAS No. 18496-38-3. Product ID: ACM18496383. Alfa Chemistry - ISO 9001:32057 Certified.
iridoid synthase
Isolated from the plant Catharanthus roseus. The reaction may involve cyclization via a Diels-Alder or Michael reaction. Iridoids are involved in the biosynthesis of many indole alkaloids. The cyclic hemiacetal is readily hydrolysed to the corresponding dial. Group: Enzymes. Enzyme Commission Number: EC 1.3.1.99. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1369; iridoid synthase; EC 1.3.1.99. Cat No: EXWM-1369.
Iriflophenone
Iriflophenone, isolated from Aquilaria sinensis, stimulates MCF-7 and T-47D human breast cancer cells proliferation[1][2]. Uses: Scientific research. Category: Natural products. CAS No. 52591-10-3. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg. Product ID: HY-N4010.
Iriflophenone
Iriflophenone is a natural xanthone found in the herbs of Aquilaria sinensis. Alternative Names: (4-hydroxyphenyl)(2,4,6-trihydroxyphenyl)-;Iriflophenone. Grades: >98%. CAS No. 52591-10-3. Molecular formula: C13H10O5. Mole weight: 246.2.
Iriflophenone 2-O-rhamnoside
Iriflophenone 2-O-rhamnoside is found in the herbs of Macaranga tanarius. Alternative Names: Dimethylmatairesinol. Grades: >98%. CAS No. 943989-68-2. Molecular formula: C19H20O9. Mole weight: 392.4.
Iriflophenone 3-C-glucoside
Iriflophenone 3-C-glucoside is isolated from the herbs of Aquilaria sinensis. Alternative Names: (3-β-D-Glucopyranosyl-2,4,6-trihydroxyphenyl)(4-hydroxyphenyl)methanone. Grades: 98.5%. CAS No. 104669-02-5. Molecular formula: C19H20O10. Mole weight: 408.4.
Irigenin
Irigenin is identified as an α-glucosidase inhibitors. Also, it is a lead compound to overcome Fibronectin EDA induced metastatic progression in lung carcinoma cells. Group: Biochemicals. Alternative Names: 3',5,7-Trihydroxy-4',5',6-trimethoxy-isoflavone; 5,7-Dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxy-4H-1-benzopyran-4-one. Grades: Highly Purified. CAS No. 548-76-5. Pack Sizes: 1mg, 2mg, 5mg, 10mg, 25mg. Molecular Formula: C??H??O?, Molecular Weight: 360.31. US Biological Life Sciences.
Worldwide
Irigenin
Irigenin is a is a lead compound, and mediates its anti-metastatic effect by specifically and selectively blocking α9β1 and α4β1 integrins binding sites on C-C loop of Extra Domain A (EDA). Irigenin shows anti-cancer properties. It sensitizes TRAIL-induced apoptosis via enhancing pro-apoptotic molecules in gastric cancer cells[1]. Uses: Scientific research. Category: Signaling pathways. CAS No. 548-76-5. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 20 mg; 50 mg; 100 mg. Product ID: HY-N2587.
Irigenin
Irigenin is a natural compound isolated from the rhizomes of Belamcanda chinensis (L.) DC. Irigenin prevents metastatic capacity of lung cancer cells by selectively blocking Extra Domain A. Irigenin has anti-inflammatory effects that can inhibit the expression of inducible nitric oxide synthase (iNOS) and cyclooxygenase (COX)-2 proteins and mRNAs without an appreciable cytotoxic effect. Alternative Names: 5,7-dihydroxy-3-(3-hydroxy-4,5-dimethoxyphenyl)-6-methoxychromen-4-one. Grades: 98.0%. CAS No. 548-76-5. Molecular formula: C18H16O8. Mole weight: 360.31.
Irinotecan
Irinotecan ((+)-Irinotecan) is a topoisomerase I inhibitor, preventing religation of the DNA strand by binding to topoisomerase I-DNA complex[1][5]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: (+)-Irinotecan; CPT-11; VAL-413free base. CAS No. 97682-44-5. Pack Sizes: 10 mM * 1 mL in DMSO; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-16562.
Irinotecan
Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively. It is used for the treatment of colon and rectum cancers. It binds to topoisomerase I-DNA complex, preventing religation of the DNA strand and leading to double-strand DNA breakage and cell death. Uses: Anticancer drug. Alternative Names: Irinophore C; Irinotecan lactone; Irinotecan mylan; Onivyde; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline, [1,4'-Bipiperidine]-1'-carboxylic Acid deriv.; (S)-[1,4'-Bipiperidine]-1'-carboxylic Acid 4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl Ester; Camptosar; Irinotecanum; CPT-11; CPT 11; CPT11; (+)-Irinotecan. Grades: ≥98%. CAS No. 97682-44-5. Molecular formula: C33H38N4O6. Mole weight: 586.68.
Irinotecan
Irinotecan. Group: Biochemicals. Grades: Highly Purified. CAS No. 97682-44-5. Pack Sizes: 50mg, 100mg, 250mg, 500mg, 1g. Molecular Formula: C33H38N4O6. US Biological Life Sciences.
Worldwide
Irinotecan Carboxylate Sodium Salt
Carboxylate form of Irinotecan. Group: Biochemicals. Alternative Names: (αS)-lizino[1,2-b]quinoline-7-acetic Acid Sodium Salt. Grades: Highly Purified. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Irinotecan (CPT-11)
Irinotecan is a topoisomerase I inhibitor for LoVo cells and HT-29 cells with IC50 of 15.8 μM and 5.17 μM, respectively. Group: Inhibitors. Alternative Names: (+)-Irinotecan,CPT-11. CAS No. 97682-44-5. Pack Sizes: 100mg. Product ID: S1198. Formula: C33H38N4O6. Smiles: CCC1=C2CN3C(=CC4=C(C3=O)COC(=O)C4(CC)O)C2=NC5=C1C=C(C=C5)OC(=O)N6CCC(CC6)N7CCCCC7. Storage Conditions: 2 years -80 in solvent.
United States; Europe
Irinotecan-[d10] Hydrochloride
Irinotecan-[d10] Hydrochloride is the labelled analogue of Irinotecan, which is a DNA topoisomerase inhibitor. Alternative Names: Irinotecan D10 Hydrochloride. Grades: 95% by HPLC; 95% atom D. CAS No. 718612-62-5. Molecular formula: C33H29D10ClN4O6. Mole weight: 633.20.
Irinotecan-d10 Hydrochloride
Deuterated Irinotecan, a DNA topoisomerase inhibitor. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
Irinotecan EP Impurity A
Irinotecan EP Impurity A. Uses: For analytical and research use. Alternative Names: (S)-4-ethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate. CAS No. 103816-16-6. Molecular formula: C31H34N4O6. Mole weight: 558.62. Catalog: APB103816166.
Irinotecan EP Impurity A
An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Alternative Names: (S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione-9-yl (1,4'-bipiperidine)-1'-carboxylate; 11-Desethyl Irinotecan. Grades: > 95%. CAS No. 103816-16-6. Molecular formula: C31H34N4O6. Mole weight: 558.64.
Irinotecan EP Impurity B
10-Hydroxycamptothecin inhibits the growth of BT-20 and MDA-231 cell with IC50 of 34.3 nM and 7.27 nM, respectively, more potently than camptothecin (CPT) with IC50 of >500 nM. 10-Hydroxycamptothecin is also an impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Uses: Anti-cancer. Alternative Names: 10-Hydroxycamptothecin; Irinotecan Related Compound A; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (4S)-; (4S)-4-Ethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 1H-Pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione, 4-ethyl-4,9-dihydroxy-, (S)-; Camptothecine, 10-hydroxy-; (+)-10-Hydroxycamptothecin; (S)-10-Hydroxycamptothecin; 10-HCPT; 10-Hydroxycamptothecin; 10-Hydroxycamptothecine; Hydroxycamptothecin; NSC 107124; USP Irinotecan Related Compound A; Irinotecan USP Related Compound A. Grades: >98%. CAS No. 19685-09-7. Molecular formula: C20H16N2O5. Mole weight: 364.35.
Irinotecan EP Impurity B
Irinotecan EP Impurity B. Uses: For analytical and research use. CAS No. 19685-09-7. Molecular formula: C20H16N2O5. Mole weight: 364.36. Catalog: APB19685097.
Irinotecan EP Impurity C
Irinotecan EP Impurity C. Uses: For analytical and research use. Alternative Names: (S)-4,8,11-triethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate. CAS No. 947687-02-7. Molecular formula: C35H42N4O6. Mole weight: 614.73. Catalog: APB947687027.
Irinotecan EP Impurity C
An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Alternative Names: 8-ethyl irinotecan; (S)-4,8,11-Triethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione-9-yl (1,4'-bipiperidine)-1'-carboxylate. Grades: 95%. CAS No. 947687-02-7. Molecular formula: C35H42N4O6. Mole weight: 614.75.
Irinotecan EP Impurity D
Irinotecan EP Impurity D. Uses: For analytical and research use. CAS No. 7689-3-4. Molecular formula: C20H16N2O4. Mole weight: 348.36. Catalog: APB7689034.
Irinotecan EP Impurity E
Irinotecan EP Impurity E. Uses: For analytical and research use. CAS No. 86639-52-3. Molecular formula: C22H20N2O5. Mole weight: 392.41. Catalog: APB86639523.
Irinotecan EP Impurity E (SN-38)
An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. It inhibits DNA and RNA synthesis with IC50s of 0.077 and 1.3 μM, respectively. Uses: The treatment of colorectal cancer. Alternative Names: (4S)-4,11-Diethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)dione; 10-Hydroxy-7-ethylcamptothecin; SN 38 Lactone; Irinotecan EP Impurity E; SN-38; USP Irinotecan Related Compound B; Irinotecan Related Compound B; Irinotecan EP Impurity E; NSC-673596. Grades: ≥95%. CAS No. 86639-52-3. Molecular formula: C22H20N2O5. Mole weight: 392.40.
Irinotecan EP Impurity F
Irinotecan EP Impurity F. Uses: For analytical and research use. CAS No. 78287-27-1. Molecular formula: C22H20N2O4. Mole weight: 376.41. Catalog: APB78287271.
Irinotecan EP Impurity G
An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Alternative Names: (4S)-4,8,11-Triethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; 7,11-Diethyl-10-hydroxycamptothecin. Grades: > 95%. CAS No. 947687-01-6. Molecular formula: C24H24N2O5. Mole weight: 420.47.
Irinotecan EP Impurity G
Irinotecan EP Impurity G. Uses: For analytical and research use. Alternative Names: (S)-4,8,11-triethyl-4,9-dihydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione. CAS No. 947687-01-6. Molecular formula: C24H24N2O5. Mole weight: 420.46. Catalog: APB947687016.
Irinotecan EP Impurity H
Irinotecan EP Impurity H. Uses: For analytical and research use. CAS No. 1608617-71-5. Molecular formula: C32H36N4O6. Mole weight: 572.66. Catalog: APB1608617715.
Irinotecan EP Impurity L
An impurity of Irinotecan, a Topoisomerase I inhibitor used for the treatment of colon cancer and small cell lung cancer. Alternative Names: (R)-4,11-Diethyl-4-hydroxy-3,14-dioxo-3,4,12,14-tetrahydro-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinolin-9-yl [1,4'-bipiperidine]-1'-carboxylate; irinotecan enantiomer. CAS No. 1255644-71-3. Molecular formula: C33H38N4O6. Mole weight: 586.68.