A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
iota-Cyclodextrin is a versatile substance extensively utilized in the biomedical sector, exhibiting remarkable potential as a pharmaceutical transporter. By amplifying the solubility and stability of diverse compounds, it functions as an efficacious drug delivery compound. Empowered by its ability to form inclusion complexes, it proficiently enwraps hydrophobic compounds, thereby facilitating the research of ailments such as cancer, diabetes and cardiovascular disorders. Synonyms: Cyclomaltotetradecaose; CD14. CAS No. 156510-94-0. Molecular formula: C84H140O70. Mole weight: 2269.97.
Iotalamic acid
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Iotalamic acid
Lotalamic acid (Iothalamic acid) is a contrast agent. Uses: Scientific research. Group: Signaling pathways. Alternative Names: Iothalamic acid. CAS No. 2276-90-6. Pack Sizes: 5 mg; 10 mg. Product ID: HY-B1053.
Iothalamic Acid
Iothalamic Acid, similar to those of diatrizoic acid, as conventional ionic contrast medioum Iothalamic Acid displayed the same level of nephrotoxicity against rat and human renal epithelial cells. Synonyms: 3-acetamido-2,4,6-triiodo-5-(methylcarbamoyl)benzoic acid Acid, Iotalamic Acid, Iothalamic Acid, Methalamic Angio Conray Angio-Conray AngioConray Conray 420 Iodothalamate Iotalamic Acid Iothalamate Iothalamate, Sodium Iothalamic Acid Iothalamic Acid, Calc. Grades: 95%. CAS No. 2276-90-6. Molecular formula: C11H9I3N2O4. Mole weight: 613.91.
Iothalamic Acid
Iothalamic Acid. Group: Biochemicals. Alternative Names: 3- (Acetylamino) -2, 4, 6-triiodo-5-[ (methylamino) carbonyl]benzoic Acid; 5-Acetamido-2,4,6-triiodo-N-methylisophthalamic Acid; 5-Acetylamino-2,4,6-triiodo-N-methyl-3-isophthalamic Acid; Cysto Conray II; Iotalamic Acid; MI 216; Methalamic Acid. Grades: Highly Purified. CAS No. 2276-90-6. Pack Sizes: 5mg. US Biological Life Sciences.
Worldwide
Ioversol
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ioversol
Ioversol (MP-328) is a nonionic iodinated contrast medium (CM) that is used during a CT scan or x-ray in animal experiment. Ioversol does not damage the blood-brain barrier (BBB) in animal [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MP-328. CAS No. 87771-40-2. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-B1410.
Ioversol
Nonionic, low osmolality, radiographic contrast agent. Diagnostic aid (radiopaque medium). Group: Biochemicals. Alternative Names: N,N'-bis(2,3-dihydroxypropyl)-5-[(hydroxyacetyl)(2-hydroxyethyl)amino]-2. Grades: Highly Purified. CAS No. 87771-40-2. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ioversol Related Compound A
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ioversol related compound B
An analog of Ioversol, which has been used as a contrast medium. Synonyms: N,N'-Bis(2,3-dihydroxypropyl)-2,4,6-triiodo-5-[2-(2-hydroxyethylamino)-2-oxoethoxy]isophthalamide; N,N'-Bis(2,3-dihydroxypropyl)-5-[(N-(2-hydroxyethyl)-carbamoyl)methoxy]-2,4,6-triiodoisophthalamide. Grades: 95 %. CAS No. 104517-96-6. Molecular formula: C18H24I3N3O9. Mole weight: 807.1.
Ioversol Related Compound B
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
IOWH032
iOWH-032 is a novel and potent CFTR inhibitor (IC50=1.01 uM) in T84 and CHO-CFTR cell based assays. Synonyms: iOWH-032; IOWH032; IOWH 032. Grades: 0.99. CAS No. 1191252-49-9. Molecular formula: C22H15Br2N3O4. Mole weight: 545.187.
IOX1
IOX1, 5-Carboxy-8-hydroxyquinoline, is a potent broad?spectrum inhibitor of 2OG oxygenases, including the JmjC demethylases. IOX1 inhibits KDM4C, KDM4E, KDM2A, KDM3A and KDM6B with IC50 values of 0.6 ?M, 2.3 ?M, 1.8 ?M, 0.1 ?M and 1.4 ?M, respectively[1][2]. IOX1 also inhibits ALKBH5[3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 5852-78-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-12304.
IOX1
IOX1 is a potent and broad-spectrum inhibitor of 2OG oxygenases. Synonyms: IOX1; IOX-1; IOX 1. Grades: >98%. CAS No. 5852-78-8. Molecular formula: C10H7NO3. Mole weight: 189.17.
Histone demethylase JMJD inhibitor (IC50 values are 0.12, 0.17, 0.2, 0.3, 0.6 and 1um for JMJD3, JMJD1A, JMJD2A, JMJD2E, JMJD2C and UTX respectively). Cell permeable; inhibits JMJD2A-mediated H3K9me3 demethylation in HeLa cells. Group: Biochemicals. Grades: Highly Purified. CAS No. 5852-78-8. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
IOX2
IOX2 is a specific prolyl hydroxylase-2 ( PHD2 ) inhibitor with IC 50 of 22 nM. IOX2 regulates platelet function and arterial thrombosis by upregulating HIF-1α expression and inhibiting ROS production. IOX2 can be used in the study of thrombotic diseases [1] [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 931398-72-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg. Product ID: HY-15468.
IOX2 is a specific prolyl hydroxylase-2 (PHD2) inhibitor with IC50 of 22 nM. Synonyms: IOX2; IOX-2; IOX 2. CAS No. 931398-72-0. Molecular formula: C19H16N2O5. Mole weight: 352.346.
IOX4
IOX4 is a potent and selective triazole-based inhibitor of Hypoxia-Inducible Factor (HIF) with selectivity for Prolyl-Hydroxylase 2 (PHD2) (IC50 = 1.6 nM). IOX4 induces HIFα in cells and in wild-type mice with marked induction in the brain tissue, revealing that it is useful for studies aimed at validating the upregulation of HIF for treatment of cerebral diseases including stroke. Synonyms: Tert-butyl 6-(5-oxo-4-(1H-1,2,3-triazol-1-yl)-2,5-dihydro-1H-pyrazol-1-yl)nicotinate. Grades: ≥98%. CAS No. 1154097-71-8. Molecular formula: C15H16N6O3. Mole weight: 328.3.
IOX4
IOX4 is a selective HIF prolyl-hydroxylase 2 (PHD2) inhibitor with an IC50 value of 1.6 nM, induces HIF? in cells and in wildtype mice with marked induction in the brain tissue. IOX4 competes with and displaces 2-oxoglutarate (2OG) at the active site of PHD2[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1154097-71-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-120110.
Ioxaglic acid
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standardseuropean pharmacopoeia (ph. eur.)pharmacopoeial standards. Alternative Names: 3-[[[[3-(Acetylmethylamino)-2,4,6-triiodo-5-(methylcarbamoyl)benzoyl]amino]acetyl]amino]-5-[(2-hydroxyethyl)carbamoyl]-2,4,6-triiodobenzoic acid,Ioxaglic acid.
Ioxilan
United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards.
Ioxilan
Ioxilan is a low-osmolar, nonionic and tri-iodinated diagnostic contrast agent. Ioxilan is also an X-ray contrast agent for excretory urography and contrast enhanced computed tomographic (CECT) imaging of the head and body. Intravascular injection results in opacification of vessels in the path of flow of the contrast medium, permitting radiographic visualization of the internal structures of the human body until significant hemodilution occurs [1] [2] [3]. Uses: Scientific research. Group: Signaling pathways. CAS No. 107793-72-6. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg. Product ID: HY-109513.
Ioxilan
Ioxilan. Group: Biochemicals. Alternative Names: 5-[Acetyl(2,3-dihydroxypropyl)amino]-N1-(2,3-dihydroxypropyl)-N3-(2-hydroxyethyl)-2,4,6-triiodo-1,3-benzenedicarboxamide. Grades: Highly Purified. CAS No. 107793-72-6. Pack Sizes: 5mg, 10mg, 25mg, 50mg, 100mg. Molecular Formula: C18H24I3N3O8. US Biological Life Sciences.
Worldwide
Ioxilan(400 mg)
Ioxilan(400 mg). Uses: Designed for use in research and industrial production. Additional or Alternative Names: IOXILAN (400 MG);1,3-Benzenedicarboxamide, 5-[acetyl(2,3-dihydroxypropyl)amino]-N-(2,3-dihydroxypropyl)-N'-(2-hydroxyethyl)-2,4,6-triiodo-;Ioxitol;Oxilan 300. Product Category: Heterocyclic Organic Compound. CAS No. 107793-72-6. Molecular formula: C18H24I3N3O8. Mole weight: 791.101. Product ID: ACM107793726. Alfa Chemistry ISO 9001:2015 Certified.
Ioxitalamic Acid
A substituted 2,4,6-triiodobenzoic acid, an excellent contrast media for ventriculography, radiculography, lumbar myelography and x-rays of the cardiovascular system. Group: Biochemicals. Alternative Names: 3- (Acetylamino) -5-[[ (2-hydroxyethyl) amino]carbonyl]-2, 4, 6-triiodobenzoic Acid;3-Acetamido-2,4,6-triiodo-(N- β -hydroxyethyl) isophthalic Acid Monoamide; AG 58107; Ioxitalamate. Grades: Highly Purified. CAS No. 28179-44-4. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Ioxitalamic Acid-d4
A substituted 2,4,6-triiodobenzoic acid, an excellent contrast media for ventriculography, radiculography, lumbar myelography and x-rays of the cardiovascular system. Group: Biochemicals. Alternative Names: 3-(Acetylamino)-5-[[(2-hydroxyethyl-d4)amino]carbonyl]-2,4,6-triiodobenzoic Acid;3-Acetamido-2,4,6-triiodo-(N- β-hydroxyethyl-d4)isophthalic Acid Monoamide; AG 58107-d4; Ioxitalamate-d4. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
IOXYNIL-METHYL. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Ioxynil-methyl, 3,5-Diiodo-4-methoxybenzonitrile, AC1N3QGA, SureCN10762528, 36198_RIEDEL, 36198_FLUKA, FT-0603634, 3336-40-1. Product Category: Heterocyclic Organic Compound. CAS No. 3336-40-1. Molecular formula: C8H5I2NO. Mole weight: 384.94. Purity: 0.96. IUPACName: 3,5-diiodo-4-methoxybenzonitrile. Canonical SMILES: COC1=C(C=C(C=C1I)C#N)I. Density: 2.37g/cm³. Product ID: ACM3336401. Alfa Chemistry ISO 9001:2015 Certified.
IP-10 from rat
recombinant, expressed in E. coli, ?98% (SDS-PAGE), ?98% (HPLC), suitable for cell culture. Group: Fluorescence/luminescence spectroscopy.
IP3(1,3,4) ammonium salt
IP3(1,3,4) ammonium salt is a chemical which occurs naturally in carbachol-stimulated rat parotid glands. Ins(1,3,4)P3 inhibits Ins(3,4,5,6)P4 1-kinase which regulates Ins(3,4,5,6)P4 levels. Synonyms: D-Myo-inositol-1,3,4-triphosphate (ammonium salt); rac-(1R,2R,3R,4R,5S,6S)-3,5,6-Trihydroxycyclohexane-1,2,4-triyl tris(dihydrogen phosphate), Triammonia Salt. Grades: >97%. CAS No. 1246355-66-7. Molecular formula: C6H24N3O15P3. Mole weight: 471.19.
Ip5I
Ip5I is an anatagonist of P2X1/P2X3 receptor. Synonyms: P1, P5- Di- (inosine- 5')- pentaphosphate, sodium salt. Grades: ≥ 95% by HPLC. CAS No. 1294478-76-4. Molecular formula: C20H27N8O24P5 (free acid). Mole weight: 918.3 (free acid).
IP6K2-IN-2
IP6K2-IN-2 (Compound 6) is an IP6K2 inhibitor, with IC 50 values of 0.58 μM ( IP6K2 ), 0.86 μM ( IP6K1 ) and 3.08 μM ( IP6K3 ). IP6K2-IN-2 can be used in research of obesity [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 2967648-66-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-122706A.
IP7e
IP7e is a potent, brain-penetrant and orally active Nurr1 activator with an EC50 value of 3.9 nM[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 500164-74-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-110274.
IP7e
IP7e is a potent Nurr1 (NR4A2) activator with EC50 value of 3.9 nM, which is important in the development and maintenance of midbrain dopaminergic neurons and is independent of endogenous activation. It suppresses NF-κB signaling. It reduces severity of symptoms in mice with experimental autoimmune encephalomyelitis (EAE). It is brain penetrant and orally bioavailable. Synonyms: IP7e; IP 7e; IP-7e; isoxazolo-pyridinone 7e; 6-[4-[(2-Methoxyethoxy)methyl]phenyl]-5-methyl-3-phenyl-isoxazolo[4,5-c]pyridin-4(5H)-one. Grades: ≥98% by HPLC. CAS No. 500164-74-9. Molecular formula: C23H22N2O4. Mole weight: 390.43.
IPA 3
IPA 3. Group: Biochemicals. Grades: Purified. CAS No. 42521-82-4. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IPA 3
IPA 3. CAS No: 42521-82-4
Sarchem Laboratories New Jersey NJ
IPA-3
IPA-3 is a selective non-ATP competitive Pak1 inhibitor with IC50 of 2.5 μM, no inhibition to group II PAKs (PAKs 4-6). Synonyms: IPA-3; IPA 3; IPA3. Grades: >98%. CAS No. 42521-82-4. Molecular formula: C20H14O2S2. Mole weight: 350.45.
IPA-3
IPA-3 is a selective non-ATP competitive PAK1 inhibitor with IC 50 of 2.5 μM, and shows no inhibition to group II PAKs (PAKs 4-6). Uses: Scientific research. Group: Signaling pathways. CAS No. 42521-82-4. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-15663.
IPA-99%. Market: Industrial Additives, Cosmetics & Personal Care. Other names: Isopropal Alcohol, Isopropanol. PK Chem Industries: We supply chemicals related to Cosmetic, Personal Care, Food, Pharmaceutical, Feed, Agriculture and Mining Industries.
iPAF1C
iPAF1C is a potent inhibitor of polymerase-associated factor 1 complex (PAF1C). iPAF1C has anti-HIV activity[1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 950403-60-8. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-160267.
IPAG
IPAG is a potent NMDA receptor antagonist at σ sites. It was used as an old antipsychiatric. Synonyms: 1-(4-Iodophenyl)-3-(2-adamantyl)guanidine. Grades: ≥98% by HPLC. CAS No. 193527-91-2. Molecular formula: C17H22IN3. Mole weight: 395.29.
IPAG
IPAG is a potent sigma-1 receptor antagonist with a pK i of 4.3 [1]. IPAG induces apoptosis [2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 193527-91-2. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-100985.
IPAG
IPAG. Group: Biochemicals. Grades: Purified. CAS No. 193527-91-2. Pack Sizes: 10mg, 50mg. US Biological Life Sciences.
Worldwide
IPAM (Indole 3-propionamide)
A cell-permeable indole derivative that acts as an antioxidant and mitochondrial metabolism modifier. IPAM binds to the rate-limiting component of oxidative phosphorylation in complex I of the respiratory chain and acts as a stabilizer of energy metabolism, thereby reducing the production of reactive oxygen species (ROS). Group: Biochemicals. Alternative Names: Indole 3-propionamide. Grades: Highly Purified. CAS No. 5814-93-7. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Ipamorelin
Ipamorelin is a ghrelin mimetic displaying growth hormone (GH) releasing activity. Ipamorelin binds to ghrelin receptor (or GH secretagogue receptor, GHSR) in the brain and promotes the GH release. It has been investigated for the treatment of ileus and gastrointestinal dysmotility. Synonyms: NNC-26-0161; NNC 26-0161; NNC26-0161; NNC-260161; NNC 260161; NNC260161. CAS No. 170851-70-4. Molecular formula: C38H49N9O5. Mole weight: 711.85.
Ipatasertib
Ipatasertib (GDC-0068) is an orally active, highly selective and ATP-competitive pan- Akt inhibitor with IC 50 values of 5, 18, 8 nM for Akt1/2/3 , respectively. Ipatasertib synchronously activates FoxO3a and NF-κB through inhibition of Akt leading to p53-independent activation of PUMA. Ipatasertib also induces apoptosis in cancer cells and inhibits tumor growth in xenograft mouse models [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0068; RG7440. CAS No. 1001264-89-6. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15186.
Ipatasertib
Ipatasertib, also known as GDC-0068 is an orally bioavailable inhibitor of the serine/threonine protein kinase Akt (protein kinase B) with potential antineoplastic activity. Akt inhibitor GDC-0068 binds to and inhibits the activity of Akt in a non-ATP-competitive manner, which may result in the inhibition of the PI3K/Akt signaling pathway and tumor cell proliferation and the induction of tumor cell apoptosis. Activation of the PI3K/Akt signaling pathway is frequently associated with tumorigenesis and dysregulated PI3K/Akt signaling may contribute to tumor resistance to a variety of antineoplastic agents. Uses: Antineoplastic agents. Synonyms: GDC-0068; GDC0068; GDC 0068; RG7440; RG-7440; RG 7440; Ipatasertib. CAS No. 1001264-89-6. Molecular formula: C24H32ClN5O2. Mole weight: 458.0.
Ipatasertib dihydrochloride
Ipatasertib dihydrochloride (GDC-0068 dihydrochloride) is a highly selective and ATP-competitive pan-Akt inhibitor with IC 50 s of 5, 18 and 8 nM for Akt1 , Akt2 and Akt3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: GDC-0068 dihydrochloride; RG-7440 dihydrochloride. CAS No. 1396257-94-5. Pack Sizes: 10 mM * 1 mL; 2 mg; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg; 500 mg; 1 g. Product ID: HY-15186A.
Ipatasertib HCl
Ipatasertib, also known as GDC-0068, is a highly selective pan-Akt inhibitor targeting Akt1/2/3 (IC50= 5 nM/18 nM/8 nM in cell-free assays) with 620-fold selectivity over PKA. Ipatasertib is advancing in clinical development including a Phase 3 trial in patients with prostate cancer and three Phase 2 trials in patients with breast cancer, gastric cancer and prostate cancer. Synonyms: (S)-2-(4-chlorophenyl)-1-(4-((5R,7R)-7-hydroxy-5-methyl-6,7-dihydro-5H-cyclopenta[d]pyrimidin-4-yl)piperazin-1-yl)-3-(isopropylamino)propan-1-one hydrochloride.; GDC0068; GDC-0068; GDC 0068; RG7440; RG-7440; RG 7440; Ipatasertib; Ipatasertib hydrochloride, Ipatasertib HCl. CAS No. 1489263-16-2. Molecular formula: C24H33Cl2N5O2. Mole weight: 494.46.
Ipatasertib impurity 1
Ipatasertib impurity 1. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1001382-14-4. Molecular formula: C21H26ClN5O2. Mole weight: 415.92. Catalog: APB1001382144.
IPD Hydrochloride
IPD is an alkylsulfonate DNA crosslinker. Uses: Dna crosslinker. Synonyms: Improsulfan hydrochloride, Improsulfan HCl, Yoshi-864; Yoshi 864; Yoshi864; NSC102627; NSC-102627; NSC 102627azanediylbis(propane-3,1-diyl) dimethanesulfonate hydrochloride; 3-(3-methylsulfonyloxypropylamino)propyl methanesulfonate;hydrochloride. Grades: ≥98%. CAS No. 3458-22-8. Molecular formula: C8H20ClNO6S2. Mole weight: 325.82.
Iperoxo is a potent superagonist of muscarinic acetylcholine receptor (mAChR) that activates M1, M2 and M3 receptors with pEC50 of 9.87, 10.1 and 9.78. Iperoxo can be used for direct probing activation-related conformational transitions of muscarinic receptors when labeled with tritium[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 247079-84-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-122743.
Iperoxo iodide
Iperoxo is an extremely potent agonist of muscarinic acetylcholine receptors (mAChR). Synonyms: Iperoxo; 4-((4,5-Dihydroisoxazol-3-yl)oxy)-N,N,N-trimethylbut-2-yn-1-aminium iodide. Grades: ≥98%. CAS No. 247079-84-1. Molecular formula: C10H17N2O2·I. Mole weight: 324.16.
Ipexidine mesylate
Ipexidine mesylate is a bio-active chemical compound. Synonyms: Urea, N,N''-(1,4-Piperazinediylbis(3,1-propanediyliminocarbonimidoyl)bis(N'-hexyl-, dimethanesulfonate; CK-0569; Guanidino propyl piperazine. Grades: 98%. CAS No. 69017-90-9. Molecular formula: C28H62N10O8S2. Mole weight: 730.98.
Ipfencarbazone
Ipfencarbazone is a non-hormonal translocation-type herbicide. It is thought to inhibit the biosynthesis of very long chain fatty acids in plants. Preparations include water-dispersible agents and compound fertilizers, and application has been made for these to be used on rice plants. Synonyms: Ipfencarbazone. Grades: >98%. CAS No. 212201-70-2. Molecular formula: C18H14Cl2F2N4O2. Mole weight: 427.23.
Ipflufenoquin
Ipflufenoquin is an insecticide with the potential to control primary infection with apple scab. Ipflufenoquin should be applied between half an inch of green and fruit set [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1314008-27-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-134338.
IPI 145
IPI 145. Group: Biochemicals. Alternative Names: INK 1197; 8-Chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]-1(2H)-isoquinolinone. Grades: Highly Purified. CAS No. 1201438-56-3. Pack Sizes: 5mg. Molecular Formula: C22H17ClN6O, Molecular Weight: 416.86. US Biological Life Sciences.
Worldwide
IPI-3063
IPI-3063 is a potent and selective phosphoinoside-3-kinase (PI3K) p110δ inhibitor. IPI-3063 was shown to inhibit mouse B cell proliferation, survival, and plasmablast differentiation, and also inhibit human B cell proliferation in vitro. Synonyms: 4-Amino-6-[1-[8-(1-methyl-6-oxopyridin-3-yl)-1-oxo-2-propan-2-ylisoquinolin-3-yl]ethylamino]pyrimidine-5-carbonitrile. CAS No. 1425043-73-7. Molecular formula: C25H25N7O2. Mole weight: 455.51.
IPI-549
IPI-549, a dihydroisoquinolin derivative, has been found to be a phosphatidylinositol 3 kinase gamma inhibitor, could exhibit antineoplastic activity in solid tumors. It is still under Phase I trial. IC50: 16 nM (PI3Kγ), 3.2 μM (PI3Kα), 3.5 μM (PI3Kβ), >8.4 μM (PI3Kδ). Synonyms: IPI-549; IPI 549; IPI549; SCHEMBL16629991; (S)-2-amino-N-(1-(8-((1-methyl-1H-pyrazol-4-yl)ethynyl)-1-oxo-2-phenyl-1,2-dihydroisoquinolin-3-yl)ethyl)pyrazolo[1,5-a]pyrimidine-3-carboxamide. Grades: 98%. CAS No. 1693758-51-8. Molecular formula: C30H24N8O2. Mole weight: 528.58.
IPI-9119
IPI-9119 is an orally active, selective and irreversible FASN inhibitor with an IC50 of 0.3 nM in vitro biochemical assay. IPI-9119 inhibits tumor growth of castration-resistant prostate cancer (CRPC) xenografts mouse models[1][2]. Uses: Scientific research. Group: Signaling pathways. CAS No. 1346564-56-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-124628.