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Lenvatinib Impurity 45. Uses: For analytical and research use. CAS No. 771464-30-3. Molecular formula: C11H8ClNO3. Mole weight: 237.64. Catalog: APB771464303.
Lenvatinib Impurity 49
Lenvatinib Impurity 49. Uses: For analytical and research use. CAS No. 417721-34-7. Molecular formula: C11H9NO4. Mole weight: 219.2. Catalog: APB417721347.
Lenvatinib Impurity 50
Lenvatinib Impurity 50. Uses: For analytical and research use. Molecular formula: C24H27ClN4O7S. Mole weight: 551.01. Catalog: APB08379.
Lenvatinib Impurity 51
Lenvatinib Impurity 51. Uses: For analytical and research use. CAS No. 848133-87-9. Molecular formula: C12H10ClN3O. Mole weight: 247.68. Catalog: APB848133879.
Lenvatinib Impurity 52
Lenvatinib Impurity 52. Uses: For analytical and research use. Molecular formula: C12H12ClN3O2. Mole weight: 265.7. Catalog: APB08380.
Lenvatinib Impurity 53
Lenvatinib Impurity 53. Uses: For analytical and research use. Alternative Names: 4-amino-7-methoxyquinoline-6-carboxamide. Molecular formula: C11H11N3O2. Mole weight: 217.22. Catalog: APB01541.
Lenvatinib Impurity 54
Lenvatinib Impurity 54. Uses: For analytical and research use. Molecular formula: C26H23Cl2N5O4. Mole weight: 540.4. Catalog: APB08381.
Lenvatinib Impurity 55
Lenvatinib Impurity 55. Uses: For analytical and research use. Molecular formula: C24H21Cl2N5O3. Mole weight: 498.36. Catalog: APB08382.
Lenvatinib Impurity 56
Lenvatinib Impurity 56. Uses: For analytical and research use. Molecular formula: C26H23Cl2N5O5. Mole weight: 556.4. Catalog: APB08384.
Lenvatinib Impurity 57
Lenvatinib Impurity 57. Uses: For analytical and research use. Molecular formula: C24H20ClN5O4. Mole weight: 477.91. Catalog: APB08383.
Lenvatinib Impurity 58
Lenvatinib Impurity 58. Uses: For analytical and research use. CAS No. 2264050-65-7. Molecular formula: C21H15D4ClN4O4. Mole weight: 430.88. Catalog: APB2264050657.
Lenvatinib Impurity 59
Lenvatinib Impurity 59. Uses: For analytical and research use. Alternative Names: 2,4-dichloro-7-methoxyquinoline-6-carboxamide. CAS No. 2241758-00-7. Molecular formula: C11H8Cl2N2O2. Mole weight: 270.00. Catalog: APB2241758007.
Lenvatinib Impurity 59
Lenvatinib Impurity 59. Uses: For analytical and research use. CAS No. 796848-80-1. Molecular formula: C13H10ClNO3. Mole weight: 263.68. Catalog: APB796848801.
Lenvatinib Impurity 60
Lenvatinib Impurity 60. Uses: For analytical and research use. Alternative Names: 4,8-dichloro-7-methoxyquinoline-6-carboxamide. CAS No. 2713130-46-0. Molecular formula: C11H8Cl2N2O2. Mole weight: 270.00. Catalog: APB2713130460.
Lenvatinib Impurity 78
Lenvatinib Impurity 78. Uses: For analytical and research use. CAS No. 2380197-89-5. Molecular formula: C17H14ClN3O3. Mole weight: 343.77. Catalog: APB2380197895.
Lenvatinib Impurity 8
Lenvatinib Impurity 8. Uses: For analytical and research use. CAS No. 1882873-21-3. Molecular formula: C21H17ClN4O3. Mole weight: 408.84. Catalog: APB1882873213.
Lenvatinib Impurity D
Lenvatinib Impurity D. Uses: For analytical and research use. CAS No. 417717-04-5. Molecular formula: C20H17ClN4O4. Mole weight: 412.83. Catalog: APB417717045.
Lenvatinib Impurity E
Lenvatinib Impurity E. Uses: For analytical and research use. CAS No. 417717-20-5. Molecular formula: C22H20ClN3O5. Mole weight: 441.87. Catalog: APB417717205.
Lenvatinib Impurity F
Lenvatinib Impurity F. Uses: For analytical and research use. CAS No. 417717-21-6. Molecular formula: C21H18ClN3O5. Mole weight: 427.84. Catalog: APB417717216.
Lenvatinib Impurity LFS-A
Lenvatinib Impurity LFS-A. Uses: For analytical and research use. CAS No. 796848-79-8. Molecular formula: C10H11ClN2O2. Mole weight: 226.66. Catalog: APB796848798.
Lenvatinib Impurity LFS-B
Lenvatinib Impurity LFS-B. Uses: For analytical and research use. CAS No. 417721-36-9. Molecular formula: C11H9ClN2O2. Mole weight: 236.66. Catalog: APB417721369.
Lenvatinib Impurity LFS-C
Lenvatinib Impurity LFS-C. Uses: For analytical and research use. CAS No. 2143930-76-9. Molecular formula: C20H19ClN4O4. Mole weight: 414.85. Catalog: APB2143930769.
Lenvatinib Impurity LFS-D
Lenvatinib Impurity LFS-D. Uses: For analytical and research use. CAS No. 2143930-77-0. Molecular formula: C13H14N2O3. Mole weight: 246.27. Catalog: APB2143930770.
Lenvatinib Impurity LFS-E
Lenvatinib Impurity LFS-E. Uses: For analytical and research use. CAS No. 417714-14-8. Molecular formula: C21H20N4O4. Mole weight: 392.42. Catalog: APB417714148.
Lenvatinib Impurity LFS-F
Lenvatinib Impurity LFS-F. Uses: For analytical and research use. CAS No. 2110414-05-4. Molecular formula: C11H10N2O3. Mole weight: 218.21. Catalog: APB2110414054.
Lenvatinib Impurity LFS-G
Lenvatinib Impurity LFS-G. Uses: For analytical and research use. CAS No. 2613141-84-5. Molecular formula: C31H29ClN6O6. Mole weight: 617.06. Catalog: APB2613141845.
Lenvatinib Impurity LFS-H
Lenvatinib Impurity LFS-H. Uses: For analytical and research use. CAS No. 417722-93-1. Molecular formula: C17H14ClN3O3. Mole weight: 343.77. Catalog: APB417722931.
Lenvatinib Impurity LFS-I
Lenvatinib Impurity LFS-I. Uses: For analytical and research use. CAS No. 2143930-75-8. Molecular formula: C35H26Cl2N6O7. Mole weight: 713.53. Catalog: APB2143930758.
Lenvatinib Impurity LFS-J
Lenvatinib Impurity LFS-J. Uses: For analytical and research use. CAS No. 1788901-86-9. Molecular formula: C21H19ClN4O5. Mole weight: 442.86. Catalog: APB1788901869.
Lenvatinib Impurity LFS-K
Lenvatinib Impurity LFS-K. Uses: For analytical and research use. CAS No. 417719-51-8. Molecular formula: C18H15ClN4O4. Mole weight: 386.79. Catalog: APB417719518.
Lenvatinib Impurity LFS-L
Lenvatinib Impurity LFS-L. Uses: For analytical and research use. Molecular formula: C17H14N2O3. Mole weight: 294.31. Catalog: APB08365.
Lenvatinib Impurity LFS-M
Lenvatinib Impurity LFS-M. Uses: For analytical and research use. Molecular formula: C19H16ClN3O5. Mole weight: 401.8. Catalog: APB08367.
Lenvatinib Impurity LFZZ-8
Lenvatinib Impurity LFZZ-8. Uses: For analytical and research use. Molecular formula: C44H40Cl2N8O8. Mole weight: 879.75. Catalog: APB08366.
Lenvatinib Liposome
Lenvatinib is a type I tyrosine kinase inhibitor that exhibits potent anti-angiogenic activity in cancer therapy. This product is a pre-formulated liposome encapsulating Lenvatinib. It is only for research purposes. Group: Drug-loaded liposome.
Lenvatinib mesylate
Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E7080 mesylate. CAS No. 857890-39-2. Pack Sizes: 10 mM * 1 mL in DMSO; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-10981A.
Lenvatinib (Standard)
Lenvatinib (Standard) is the analytical standard of Lenvatinib. This product is intended for research and analytical applications. Lenvatinib (E7080) is an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3, FGFR1-4, PDGFR, KIT, and RET, shows potent antitumor activities[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: E7080 (Standard). CAS No. 417716-92-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-10981R.
Lenzilumab
Lenzilumab (KB 003) is a human monoclonal antibody targeting CSF2/GM-CSF for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies[1][2]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: KB 003. CAS No. 1229575-09-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99207.
Leonurine
Leonurine. Group: Biochemicals. Alternative Names: 4-Guanidinobutyl syringate. Grades: Plant Grade. CAS No. 24697-74-3. Pack Sizes: 20mg. Molecular Formula: C14H21N3O5, Molecular Weight: 311.334. US Biological Life Sciences.
Worldwide
Leonurine Hydrochloride
Leonurine Hydrochloride. Group: Biochemicals. Grades: Plant Grade. CAS No. 24735-18-0. Pack Sizes: 20mg. Molecular Formula: C14H22ClN3O5, Molecular Weight: 347.8. US Biological Life Sciences.
Worldwide
LEP (116-130) (mouse)
LEP (116-130) (mouse). Group: Biochemicals. Grades: Purified. CAS No. 258276-95-8. Pack Sizes: 1mg. US Biological Life Sciences.
Worldwide
LEP (116-130) (mouse) TFA
LEP (116-130) (mouse) TFA is a synthetic leptin peptide fragment. Synonyms: Leptin Fragment 116-130 Amide mouse TFA; LEP(116-130) (mouse) TFA; H-Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2.TFA; L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-seryl-glycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-alpha-glutamyl-L-serinamide trifluoroacetic acid; L-Serinamide, L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-serylglycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-α-glutamyl-, 2,2,2-trifluoroacetate (1:1). Grade: ≥95%. CAS No. 2828433-16-3. Molecular formula: C66H110F3N19O26S. Mole weight: 1674.77.
25g Pack Size. Group: Building Blocks, Organics, Stains & Indicators. Formula: C10H9N. CAS No. 491-35-0. Prepack ID 40487028-25g. Molecular Weight 143.19. See USA prepack pricing.
L-(-)-Epinephrine
Endogenous catcholamine with combined α-and β-agonist activity. Principal sympathomimetic hormone produced by the adrenal medulla. Bronchodilator; cardiostimulant; mydriatic; antiglaucoma. Group: Biochemicals. Alternative Names: 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol; (R)-Epinephrine; Renoform; Renostypticin; Adnephrine; Adrenal; Adrenalin; Adrenaline; l-Epinephrine; Levoepinephrine. Grades: Highly Purified. CAS No. 51-43-4. Pack Sizes: 100mg. US Biological Life Sciences.
a,b-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP. Group: Biochemicals. Grades: Highly Purified. CAS No. 51-42-3. Pack Sizes: 100mg. US Biological Life Sciences.
Worldwide
Lepirudin
Lepirudin is an anticoagulant that acts as a direct thrombin inhibitor. Lepirudin binds to both free and clot-bound thrombin. Lepirudin is approved for the treatment of heparin-induced thrombocytopenia (HIT). Uses: The treatment of heparin-induced thrombocytopenia (hit). Synonyms: (Leu1,Thr2)-Hirudin (desulfated); Lepirudin; Refludan; Refludin; Hbw 023; Hbw-023; Hbw023. CAS No. 138068-37-8. Molecular formula: C287H440N80O111S6. Mole weight: 6979.41.
Leprapinic acid
Leprapinic acid is a member of methoxybenzenes. Synonyms: Leprapic acid; methyl (E)-2-(3-hydroxy-5-oxo-4-phenylfuran-2(5H)-ylidene)-2-(2-methoxyphenyl)acetate; Benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-methoxy-, methyl ester, (E)-; α-[(2E)-3-Hydroxy-5-oxo-4-phenyl-2,5-dihydrofuran-2-ylidene]-2-methoxybenzeneacetic acid methyl ester; Benzeneacetic acid, α-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-methoxy-, methyl ester, (αE)-; [3-Hydroxy-5-oxo-4-phenyl-5H-furan-(2E)-ylidene]-(2-methoxy-phenyl)-acetic acid methyl ester. CAS No. 481-59-4. Molecular formula: C20H16O6. Mole weight: 352.34.
2,7-Dichloronorlichexanthone is a lichen chromone found in ascomycete licheniformis. Synonyms: Glutaconic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester (8CI); 1-[(5-Hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] 3-methyl-2-pentenedioate; Fuciformic acid; 2-Pentenedioic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester. CAS No. 22399-41-3. Molecular formula: C18H18O8. Mole weight: 362.33.
Leprolomin
It is a novel diphenyl ether isolated from the lichen psoroma leprolomum. Synonyms: Ethanone, 1-[6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl]-; 1-(6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl)ethan-1-one; NSC 646011. Grade: ≥98%. CAS No. 68984-67-8. Molecular formula: C20H22O8. Mole weight: 390.38.
Leptin (116-130) (human)
Leptin (116-130) (human) is a fragment of human leptin, which is an adipose tissue-derived protein encoded by an obesity gene and is involved in controlling food intake, energy expenditure and reproduction, as well as playing a role in immune regulation, inflammation, and hematopoiesis. Synonyms: Obese Gene Peptide (116-130) (human); L-Serine, L-seryl-L-cysteinyl-L-histidyl-L-leucyl-L-prolyl-L-tryptophyl-L-alanyl-L-serylglycyl-L-leucyl-L-α-glutamyl-L-threonyl-L-leucyl-L-α-aspartyl-; H-Ser-Cys-His-Leu-Pro-Trp-Ala-Ser-Gly-Leu-Glu-Thr-Leu-Asp-Ser-OH; L-seryl-L-cysteinyl-L-histidyl-L-leucyl-L-prolyl-L-tryptophyl-L-alanyl-L-seryl-glycyl-L-leucyl-L-alpha-glutamyl-L-threonyl-L-leucyl-L-alpha-aspartyl-L-serine. Grade: ≥95%. CAS No. 2243207-12-5. Molecular formula: C70H106N18O24S. Mole weight: 1615.76.
Leptin (22-56), human
Leptin (22-56) (human) is the fragment of leptin, a hormone produced by the fat cells in human body. Synonyms: H-Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH; L-valyl-L-prolyl-L-isoleucyl-L-glutaminyl-L-lysyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-alpha-aspartyl-L-threonyl-L-lysyl-L-threonyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-isoleucyl-L-valyl-L-threonyl-L-arginyl-L-isoleucyl-L-asparagyl-L-alpha-aspartyl-L-isoleucyl-L-seryl-L-histidyl-L-threonyl-L-glutaminyl-L-seryl-L-valyl-L-seryl-L-seryl-L-lysyl-L-glutaminyl-L-lysine. Grade: >95%. CAS No. 183598-56-3. Molecular formula: C171H298N50O56. Mole weight: 3950.49.
Leptin (22-56), human
Leptin (22-56), human is the fragment of leptin, mediated via several isoforms of receptors (Ob-Rs). Uses: Scientific research. Category: Signaling pathways. CAS No. 183598-56-3. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1523.
Leptin Fragment 116-130 Amide mouse
A synthetic leptin peptide fragment. Synonyms: LEP 116-130. Grade: >95%. CAS No. 258276-95-8. Molecular formula: C64H109N19O24S. Mole weight: 1560.73.
Leptin (human)
Leptin (human) is a peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Synonyms: 1: PN: WO0038651 SEQID: 1 unclaimed protein; 22-167-Protein (human gene obese 167-amino acid isoform precursor); Anti-obesity protein (human); Leptin (human clone 3 gene Ob); Leptin (human gene ob protein 146-amino acid fragment); Leptin (synthetic human mutant 15B); Protein (human gene ob active isoform). Grade: ≥95% by HPLC. CAS No. 177404-21-6.
Leptocillin
Leptocillin is extracted from Leptoaphaeria sp. L-179. It is resistant to several Gram-positive bacteria (Staphylococcus aureus 209P, Bacillus subtilis No. 119) and several Gram-negative bacteria (Klebsiella pneumoniae 22 # 3038, proteus singular GN310). Synonyms: Antibiotic MK4588; MK 4588; MK-4588; 7-(1-Isocyano-2-(4-methoxyphenyl))ethenyl-1-hydroxy-7-isocyanobicyclo(4,2,0)oct-2-en-4-one. CAS No. 123949-57-5. Molecular formula: C19H16N2O3. Mole weight: 320.34.
Leptofuranin A
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H48O5. Mole weight: 512.72.
Leptofuranin B
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H50O5. Mole weight: 526.75.
Leptofuranin C
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H46O5. Mole weight: 510.70.
Leptofuranin D
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H48O5. Mole weight: 524.73.
Leptoglycin
Leptoglycin is an antibacterial peptide isolated from Leptodactylus pentadactylus. Leptoglycin was able to inhibit the growth of Gram-negative bacteria Pseudomonas aeruginosa, Escherichia coli and Citrobacter freundii with minimal inhibitory concentrations (MICs) of 8 microM, 50 microM, and 75 microM respectively, but it did not show antimicrobial activity against Gram-positive bacteria (Staphylococcus aureus, Micrococcus luteus and Enterococcus faecalis), yeasts (Candida albicans and Candida tropicalis) and dermatophytes fungi (Microsporum canis and Trichophyton rubrum). Synonyms: Gly-Leu-Leu-Gly-Gly-Leu-Leu-Gly-Pro-Leu-Leu-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Leu-Leu.
Leptolstatin
It is produced by the strain of Str. sp. SAM1595. It has no activity against bacteria, fungi and yeast, in addition to Millet wine schizozoite yeast (MIC is 0.4 μg/mL). It has a strong inhibitory effect on mammalian cells, such as normal fibroblast 3Y1 cells in rats (IC50 is 0.4 ng/mL). Synonyms: 2H-Pyran-2-one, 6-[(1E,3Z,5R,7E,9E,11R,13S,14R,15S,17E)-14,19-dihydroxy-3,5,9,11,13,15,17-heptamethyl-12-oxo-1,3,7,9,17-nonadecapentaen-1-yl]-5,6-dihydro-, (6R)-; (R)-6-((1E,3Z,5R,7E,9E,11R,13S,14R,15S,17E)-14,19-dihydroxy-3,5,9,11,13,15,17-heptamethyl-12-oxononadeca-1,3,7,9,17-pentaen-1-yl)-5,6-dihydro-2H-pyran-2-one. CAS No. 149633-91-0. Molecular formula: C31H46O5. Mole weight: 498.69.
Leptomycin A
a potent anti-fungal antibiotic. Leptomycin A is a highly specific inhibitor of export protein CRM1. Synonyms: Leptomycin A; Jildamycin; 87081-36-5; (2E,10E,12E,16E,18E)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid; NSC 369326; NSC369326; ATS1287 A, LMA; SCHEMBL14190847; MFCD01711669; BS-1083; NSC-369326; 19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-2,10,12,16,18-nonadecapentaenoic acid; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-; DA-54856; NS00011727; Leptomycin A; Antibiotic ATS 1287A; Antibiotic PD 118607; Jildamycin; (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-6-Hydroxy-3,5,7,9,11,15,17-heptamethyl-19-[(2S,3S)-3-methyl-6-oxo-2,3-dihydropyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid; 2,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-. Grade: >99% by HPLC. CAS No. 87081-36-5. Molecular formula: C12H14N2O3S. Mole weight: 266.32.
Leptomycin B
a potent anti-fungal antibiotic. Leptomycin B is an inhibitor of export protein CRM1. Synonyms: 19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-Nonadecapentaenoic Acid; Elactocin; Mantuamycin; Antibiotic CI 940; PD 114720. CAS No. 87081-35-4. Molecular formula: C33H48O6. Mole weight: 540.73.
Leptomycin B
Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CI 940; LMB. CAS No. 87081-35-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-16909.
Leptomycin B (LMB)
Leptomycin B (LMB, CI 940, Elactocin, Mantuamycin, NSC 364372) is a potent antifungal antibiotic isolated from Streptomyces and acts as a specific inhibitor of the nuclear export factor CRM1. Leptomycin B rapidly induces cytotoxic effects in cancer cell lines via covalent inhibition of CRM1 with IC50 values of 0.1 nM-10 nM. Group: Inhibitors. Alternative Names: LMB, CI 940, Elactocin, Mantuamycin, NSC 364372. CAS No. 87081-35-4. Pack Sizes: 5mg. Product ID: S7580. Formula: C33H48O6. Storage Conditions: 3 years -20°C powder.
United States; Europe
Leptosin I
It is produced by the strain of I Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.13 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (5alpha,6S,6'S,15alpha)-; (+)-Leptosin I; 22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2'',3'':2',3'][1,2,3,4,6]tetrathiazocino[6'',5'':1',5']pyrrolo[3',4':6,7]pyrazino[2''',1''':2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone,2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3a,5ab,10ba,10cS*,15ab,18b,22ab,22ba,23aa,24S*)-(+)-; Leptosine I. CAS No. 160472-96-8. Molecular formula: C32H32N6O7S4. Mole weight: 740.89.
Leptosin J
It is produced by the strain of J Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.25 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (2alpha,5alpha,6S,6'S,15alpha)-; 22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2'',3'':2',3'][1,2,3,4,6]tetrathiazocino[6'',5'':1',5']pyrrolo[3',4':6,7]pyrazino[2''',1''':2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone,2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3a,5aa,10bb,10cR*,15aa,18a,22aa,22bb,23ab,24R*)-(+)-; Leptosine J. CAS No. 160550-15-2. Molecular formula: C32H32N6O7S4. Mole weight: 740.89.
LEQ803
LEQ803 (N-Desmethyl Ribociclib) is a drug metabolite of the CDK4/6 inhibitor Ribociclib (HY-15777), which is produced through metabolism by CYP3A4. LEQ803 has potential application value in the field of oncology[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Desmethyl Ribociclib. CAS No. 1211441-59-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171459.
Lercanidipine
Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine-calcium channel blocker with a pIC50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 100427-26-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0612.