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| Product | Description | |
|---|---|---|
| Leptomycin A | a potent anti-fungal antibiotic. Leptomycin A is a highly specific inhibitor of export protein CRM1. Synonyms: Leptomycin A; Jildamycin; 87081-36-5; (2E,10E,12E,16E,18E)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid; NSC 369326; NSC369326; ATS1287 A, LMA; SCHEMBL14190847; MFCD01711669; BS-1083; NSC-369326; 19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-2,10,12,16,18-nonadecapentaenoic acid; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-; DA-54856; NS00011727; Leptomycin A; Antibiotic ATS 1287A; Antibiotic PD 118607; Jildamycin; (2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-6-Hydroxy-3,5,7,9,11,15,17-heptamethyl-19-[(2S,3S)-3-methyl-6-oxo-2,3-dihydropyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid; 2,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-. Grade: >99% by HPLC. CAS No. 87081-36-5. Molecular formula: C12H14N2O3S. Mole weight: 266.32. |  |
| Leptomycin A | from Streptomyces sp., ~95% (HPLC), methanol solution. Group: Fluorescence/luminescence spectroscopy. |  |
| Leptomycin A (Antibiotic ATS 1287A, Antibiotic PD 118607, Jildamycin) | Leptomycin A, a methyl (cf. ethyl) analogue of Leptomycin B, is a minor component of the leptomycin complex produced by selected Streptomyces species. Leptomycin B is a potent inhibitor of the nuclear transport receptor CRM1. Leptomycin A is also likely to inhibit nuclear transport and may offer differences in exporter selectivity. Leptomycin A shows antimicrobial activity against Schizosaccaromyces pombe and Mucor rouxianus. Group: Biochemicals. Alternative Names: Antibiotic ATS 1287A, Antibiotic PD 118607, Jildamycin. Grades: Highly Purified. CAS No. 87081-36-5. Pack Sizes: 100ug. US Biological Life Sciences. |  Worldwide |
| Leptomycin B | Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI 940; LMB. CAS No. 87081-35-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-16909. |  |
| Leptomycin B | a potent anti-fungal antibiotic. Leptomycin B is an inhibitor of export protein CRM1. Synonyms: 19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-Nonadecapentaenoic Acid; Elactocin; Mantuamycin; Antibiotic CI 940; PD 114720. CAS No. 87081-35-4. Molecular formula: C33H48O6. Mole weight: 540.73. | |
| Leptomycin B (Elactocin, Antibiotic ATS 1287B, Antibiotic CI 940, Antibiotic CL 1957A, Antibiotic PD 114720, Mantuamycin) | Leptomycin B is the dominant and most studied member of the leptomycin class isolated from selected Streptomyces strains. Leptomycin B is a nanomolar active and specific nuclear export inhibitor. Its target is CRM1/exportin1 a protein in the nuclear export sequence (NES). Examples of proteins affected are c-Abl, cyclin B1, HIV-1 Rev, IκB, MPF, MAP/ERK, MDM2/p53, NF-κB/IκB7 and PKA. Export of many RNAs are also inhibited e.g. COX-2 and c-FOS mRNA. In addition Leptomycin B shows antifungal and antibacterial and potent antitumour activities. Group: Biochemicals. Alternative Names: Elactocin, Antibiotic ATS 1287B, Antibiotic CI 940, Antibiotic CL 1957A, Antibiotic PD 114720, Mantuamycin. Grades: Highly Purified. CAS No. 87081-35-4. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
| Leptomycin B, Free Acid (Elactocin, Antibiotic ATS 1287B, Antibiotic CI 940, Antibiotic CL 1957A, Antibiotic PD 114720, Mantuamycin) | Leptomycin B (LepB) is a potent, specific inhibitor of nuclear export signal (NES)-dependent protein export from the nucleus. Group: Biochemicals. Grades: Highly Purified. CAS No. 87081-35-4. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| Leptomycin b from streptomyces sp | Leptomycin b from streptomyces sp. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Leptomycin B, Elactocin, Probes1_000170, Probes2_000132, NSC364372, CID5458861, 87081-35-4, 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-, 2,10,12,16,18-Nonadecaptentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-. Product Category: Heterocyclic Organic Compound. Appearance: White crystalline solid. CAS No. 87081-35-4. Molecular formula: C33H48O6. Mole weight: 540.736. Purity: Purity >95% (HPLC). IUPACName: (2E,10E,12E,16E,18E)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid. Density: 1.072 g/cm³. Product ID: ACM87081354. Alfa Chemistry ISO 9001:2015 Certified. |  |
| Leptosin I | It is produced by the strain of I Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.13 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (5alpha,6S,6'S,15alpha)-; (+)-Leptosin I; 22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2'',3'':2',3'][1,2,3,4,6]tetrathiazocino[6'',5'':1',5']pyrrolo[3',4':6,7]pyrazino[2''',1''':2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone,2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3a,5ab,10ba,10cS*,15ab,18b,22ab,22ba,23aa,24S*)-(+)-; Leptosine I. CAS No. 160472-96-8. Molecular formula: C32H32N6O7S4. Mole weight: 740.89. | |
| Leptosin J | It is produced by the strain of J Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.25 μg/mL. Synonyms: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (2alpha,5alpha,6S,6'S,15alpha)-; 22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2'',3'':2',3'][1,2,3,4,6]tetrathiazocino[6'',5'':1',5']pyrrolo[3',4':6,7]pyrazino[2''',1''':2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone,2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3a,5aa,10bb,10cR*,15aa,18a,22aa,22bb,23ab,24R*)-(+)-; Leptosine J. CAS No. 160550-15-2. Molecular formula: C32H32N6O7S4. Mole weight: 740.89. | |
| Leptospermone | Leptospermone is a competitive, reversible inhibitor for p-Hydroxyphenylpyruvate dioxygenase ( HPPD ), with an IC 50 of 12.1 μM. Leptospermone exhibits herbicidal activity for its bleaching effect [1]. Uses: Scientific research. Group: Natural products. CAS No. 567-75-9. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-114991. | |
| Lercanidipine | Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine- calcium channel blocker with a pIC 50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 100427-26-7. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0612. | |
| Lercanidipine-[13C,d3] Hydrochloride | Lercanidipine-[13C,d3] Hydrochloride is the labelled analogue of Lercanidipine. Lercanidipine is a calcium channel blocker that is used for the treatment of hypertension. Synonyms: Lercanidipine 13C D3 Hydrochloride. Grade: 95% by HPLC; 95% atom 13C; 95% atom D. CAS No. 1261397-71-0. Molecular formula: C35[13C]H39D3ClN3O6. Mole weight: 652.20. | |
| Lercanidipine-d3 hydrochloride | Lercanidipine-d 3 (hydrochloride) is the deuterium labeled Lercanidipine. Lercanidipine is a lipophilic third-generation dihydropyridine-calcium channel blocker (DHP-CCB). Lercanidipine has long lasting antihypertensive action and reno-protective effect[1][2][3]. Uses: Scientific research. Group: Isotope-labeled compounds. CAS No. 1189954-18-4. Pack Sizes: 1 mg. Product ID: HY-B0612DS1. | |
| Lercanidipine-d3 Hydrochloride | A labeled dihydropyridine calcium channel blocker. Group: Biochemicals. Alternative Names: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)(methyl-d3)amino]-1,1-dimethylethyl Methyl Ester Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Lercanidipine hydrochloride | Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine- calcium channel blocker with a pIC 50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research [1] [2] [3] [4] [5]. Uses: Scientific research. Group: Signaling pathways. CAS No. 132866-11-6. Pack Sizes: 10 mM * 1 mL; 50 mg; 100 mg; 250 mg; 500 mg. Product ID: HY-B0612A. | |
| Lercanidipine Hydrochloride | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopyapi standardspharmaceutical toxicology. Alternative Names: Renovia, Zanicor, Corifeo, Zandip, Lercadip, Vasodip, Lercapin, Lercan, Rec 15/2375, Lercanidipine hydrochloride, Lercaton, Lervasc, Lotensyl, Lerkamen, Cardiovasc, R 75,3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-methyl ester, hydrochloride (1:1), Carmen, Lerzam, 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl methyl ester, monohydrochloride (9CI). | |
| Lercanidipine Hydrochloride | Lercanidipine hydrochloride is a L-type (Cav1.2b) vascular channel antagonist; L-type (Cav1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine. Group: Biochemicals. Alternative Names: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[ (3, 3-diphenylpropyl) methylamino]-1, 1-dimethylethyl methyl ester hydrochloride; Cardiovasc; Carmen. Grades: Highly Purified. CAS No. 132866-11-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C36H42ClN3O6. US Biological Life Sciences. | Worldwide |
| L-(+)-Ergothioneine | L-Ergothioneine is a natural molecule isolated from the rye ergot fungus and later identified in rat erythrocytes and liver and in numerous other animal tissues. Its antioxidizing properties may afford the compound therapeutic potential or it may be used as a food additive or in cosmetics. Group: Biochemicals. Alternative Names: (αS)-α-Carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium Inner Salt; 2-Mercaptohistidine Betaine; NSC 7175; 2-Mercapto-N,N-dimethylhistidine Methyl Ester Betaine; 2-Mercapto-histidine; Sympectothion; Thiasine; Thioneine; Thiotane. Grades: Highly Purified. CAS No. 497-30-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C?H??N?O?S, Molecular Weight: 229.3. US Biological Life Sciences. | Worldwide |
| L-(+)-Ergothioneine | L-(+)-Ergothioneine (ET) is a sulfur-containing amino acid, which is only produced by Actinomycetales bacteria and non-yeast like fungi belonging to the division Basidiomycota and Ascomycota. It was originally isolated from Claviceps purpurea or rye ergot. It is obtained from L-histidine, which is converted into betaine form called hercynine. It is found in both animals and plants, and mammals usually obtain it from their diet, e.g. through mushrooms or oats. It is tautomeric in nature, and in neutral aqueous solution exists in thione form. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-Ergothioneine; (+)-Ergothioneine; Thiasine; Sympectothion; Ergothionine; Erythrothioneine; Thiolhistidinebetaine. Product Category: Heterocyclic Organic Compound. Appearance: Colorless liquid. CAS No. 497-30-3. Molecular formula: C9H15N3O2S. Mole weight: 229.3. ECNumber: 207-843-5. Product ID: ACM497303. Alfa Chemistry ISO 9001:2015 Certified. | |
| L-(+)-Ergothioneine | L-(+)-Ergothioneine is a natural amino acid isolated from the rye ergot fungus and later identified in rat erythrocytes and the liver. L-(+)-Ergothioneine is an antioxidant and a unique cell physiological protective agent, which has many physiological functions such as scavenging free radicals, whitening, anti-aging, preventing ultraviolet radiation damage, maintaining DNA synthesis and normal cell growth. Synonyms: 1H-Imidazole-4-ethanaminium, α-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-, inner salt, (αS)-; (2S)-3-(2-Sulfanyl-1H-imidazol-4-yl)-2-(trimethylazaniumyl)propanoate; (S)-5-(2-Carboxy-2-(trimethylammonio)ethyl)-1H-imidazole-2-thiolate; 1H-Imidazole-4-ethanaminium, α-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-, inner salt, (S)-; 2-Mercapto-N,N-dimethylhistidine methyl ester betaine; 2-Mercaptohistidine betaine; 2-Mercaptohistidine trimethylbetaine; L-Ergothioneine; ErgoActive; Ergothioneine; Ergothionine; Histidine, 2-mercapto-, trimethylbetaine; Histidine, 2-mercapto-N,N-dimethyl-, betaine; L-(+)-Ergothionene; NSC 7175; Phytothioneine; Sympectothion; Thiasine; Thioneine; thiotaine; Thiotane. Grade: >95%. CAS No. 497-30-3. Molecular formula: C9H15N3O2S. Mole weight: 229.30. | |
| L-(+)-Ergothioneine-[d3] | L-(+)-Ergothioneine-[d3] is a stable isotope analogue of L-(+)-Ergothioneine. It is a natural molecule isolated from the rye ergot fungus and later identified in rat erythrocytes and liver and in numerous other animal tissues. Its antioxidizing properties may afford the compound therapeutic potential or it may be used as a food additive or in cosmetics. Synonyms: (αS)-α-Carboxy-2,3-dihydro-N,N,-dimethyl-N-(methyl-d3)-2-thioxo-1H-imidazole-4-ethanaminium Inner Salt; 2-Mercaptohistidine-d3 Betaine; 2-Mercapto-N,N-dimethylhistidine Methyl Ester Betaine-d3; 2-Mercaptohistidine-d3; L-(+)-Ergothioneine D3. Grade: 95% by CP; 99% atom D. CAS No. 1356933-89-5. Molecular formula: C9H12D3N3O2S. Mole weight: 232.32. | |
| L-(+)-Ergothioneine-d9 | Labeled L-Ergothionine. It is a natural molecule isolated from the rye ergot fungus and later identified in rat erythrocytes and liver and in numerous other animal tissues. Its antioxidizing properties may afford the compound therapeutic potential or it may be used as a food additive or in cosmetics. Group: Biochemicals. Alternative Names: (αS)-α-Carboxy-2,3-dihydro-N,N,N-tri(methyl-d3)-2-thioxo-1H-imidazole-4-ethanaminium Inner Salt; 2-Mercaptohistidine Betaine-d9; NSC 7175-d9; 2-Mercapto-N,N-dimethylhistidine Methyl Ester Betaine-d9; 2-Mercapto-histidine-d9; Sympectothion-d9; Thiasine-d9; Thioneine-d9; Thiotane-d9. Grades: Highly Purified. CAS No. 497-30-3-unlabeled. Pack Sizes: 1mg. Molecular Formula: C?H?D?N?O?S, Molecular Weight: 238.35. US Biological Life Sciences. | Worldwide |
| Leriglitazone | Leriglitazone (MIN-102; Hydroxypioglitazone) is an orally active and a BBB-penatrable PPARγ agonist with an EC 50 of 9 μM. Leriglitazone, as a regulator of mitochondrial function, has neuroprotective, anti-inflammatory and antioxidant effects. Leriglitazone can be used in the study of neuroinflammatory and neurodegenerative diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MIN-102; Hydroxypioglitazone. CAS No. 146062-44-4. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg. Product ID: HY-117727. | |
| Leriglitazone hydrochloride | Leriglitazone (MIN-102; Hydroxypioglitazone) hydrochloride is an orally active and a BBB-penatrable PPARγ agonist with an EC 50 of 9 μM. Leriglitazone hydrochloride, as a regulator of mitochondrial function, has neuroprotective, anti-inflammatory and antioxidant effects. Leriglitazone hydrochloride can be used in the study of neuroinflammatory and neurodegenerative diseases [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: MIN-102 hydrochloride; Hydroxypioglitazone hydrochloride. CAS No. 146062-46-6. Pack Sizes: 10 mM * 1 mL; 5 mg. Product ID: HY-117727A. | |
| Lerisetron | Lerisetron is a potent 5-HT 3 antagonists and possess high-affinity binding for the 5-HT 3 receptors with pK i value of 9.2. Lerisetron has a potent ability to inhibit the 5-HT-evoked reflex bradycardia in urethane-anesthetized rats [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 143257-98-1. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-105090. | |
| Leritrelvir | Leritrelvir (RAY1216) is an orally active SARS-CoV-2 main protease slow-tight inhibitor with a K i of 8.6 nM [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RAY1216. CAS No. 2923310-64-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153121. | |
| Lerociclib | Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6 , with IC 50 s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: G1T38. CAS No. 1628256-23-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112272. | |
| Lerociclib dihydrochloride | Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4 / CDK6 , with IC 50 s of 1 nM and 2 nM for CDK4 / CyclinD1 and CDK6 / CyclinD3 , respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: G1T38 dihydrochloride. CAS No. 2097938-59-3. Pack Sizes: 5 mg; 10 mg; 50 mg; 100 mg. Product ID: HY-112272A. | |
| Leronlimab | Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody. Leronlimab inhibits CCR5-mediated HIV-1 viral and lung metastasis in mouse tumor models. Leronlimab can be used for the research of HIV nonalcoholic steatohepatitis (NASH) and cancer [1]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: PRO 140. CAS No. 674782-26-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99697. | |
| Lersivirine | Lersivirine (UK-453061) is potent and selective non-nucleoside reverse transcription inhibitor (NNRTI; IC 50 =119 nM) with excellent efficacy against NNRTI-resistant viruses. Lersivirine exhibits potent antiretroviral activity against wild-type HIV virus and clinically relevant NNRTI-resistant strains [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: UK-453061. CAS No. 473921-12-9. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-14267. | |
| L-erythro-3,5-diaminohexanoate dehydrogenase | This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating). This enzyme is also called L-3,5-diaminohexanoate dehydrogenase. This enzyme participates in lysine degradation. Group: Enzymes. Synonyms: L-3,5-diaminohexanoate dehydrogenase. Enzyme Commission Number: EC 1.4.1.11. CAS No. 37377-90-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1444; L-erythro-3,5-diaminohexanoate dehydrogenase; EC 1.4.1.11; 37377-90-5; L-3,5-diaminohexanoate dehydrogenase. Cat No: EXWM-1444. |  |
| L-erythro-3-hydroxyaspartate aldolase | A pyridoxal-phosphate protein. The enzyme, purified from the bacterium Paracoccus denitrificans NCIMB 8944, is strictly specific for the L-erythro stereoisomer of 3-hydroxyaspartate. Different from EC 4.1.3.41, erythro-3-hydroxy-D-aspartate aldolase. Requires a divalent cation. Group: Enzymes. Synonyms: L-erythro-β-hydroxyaspartate aldolase; L-erythro-β-hydroxyaspartate glycine-lyase; erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase. Enzyme Commission Number: EC 4.1.3.14. CAS No. 37290-64-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4900; L-erythro-3-hydroxyaspartate aldolase; EC 4.1.3.14; 37290-64-5; L-erythro-β-hydroxyaspartate aldolase; L-erythro-β-hydroxyaspartate glycine-lyase; erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase. Cat No: EXWM-4900. | |
| L-erythro-α-Phenyl-2-piperidineacetamide | A byproduct obtained during the synthesis of D-threo-Methylphenidate (Ritalin). Group: Biochemicals. Alternative Names: (αR,2S)-α-Phenyl-2-piperidineacetamide. Grades: Highly Purified. CAS No. 160707-39-1. Pack Sizes: 5mg. US Biological Life Sciences. | Worldwide |
| L-erythro-methylphenidate hydrochloride | L-erythro-methylphenidate hydrochloride. Group: Biochemicals. Alternative Names: (2S,2'R)-(-)-threo-methyl a-phenyl-a-(2-piperidyl)acetate hydrochloride. Grades: Highly Purified. CAS No. 40431-63-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C14H20ClNO2. US Biological Life Sciences. | Worldwide |
| L-Erythro-pentonic acid,2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-,ethyl ester | L-Erythro-pentonic acid,2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-,ethyl ester. Uses: Designed for use in research and industrial production. Additional or Alternative Names: L-erythro-Pentonic acid, 2-deoxy-2,2-difluoro-4,5-O-(1-methylethylidene)-, ethyl ester, ZINC34067865, AKOS015965809, AC-20157, 166376-97-2. Product Category: Heterocyclic Organic Compound. CAS No. 166376-97-2. Molecular formula: C10H16F2O5. Mole weight: 254.227846 [g/mol]. Purity: 0.96. IUPACName: ethyl (3S)-3-[(4S)-2,2-dimethyl-1,3-dioxolan-4-yl]-2,2-difluoro-3-hydroxypropanoate. Density: 1.232g/cm³. Product ID: ACM166376972. Alfa Chemistry ISO 9001:2015 Certified. | |
| L-(+)-Erythrose | 100mg Pack Size. Group: Carbohydrates, Sugars. Formula: C4H8O4. CAS No. 533-49-3. Prepack ID 74151304-100mg. Molecular Weight 120.1. See USA prepack pricing. |  |
| L-erythrulose 1-phosphate isomerase | The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism. Group: Enzymes. Synonyms: eryH (gene name). Enzyme Commission Number: EC 5.3.1.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5473; L-erythrulose 1-phosphate isomerase; EC 5.3.1.33; eryH (gene name). Cat No: EXWM-5473. | |
| L-erythrulose 4-kinase | The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of L-threitol. Group: Enzymes. Synonyms: lerK (gene name). Enzyme Commission Number: EC 2.7.1.209. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3044; L-erythrulose 4-kinase; EC 2.7.1.209; lerK (gene name). Cat No: EXWM-3044. | |
| L-erythrulose 4-phosphate epimerase | The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of L-threitol. Group: Enzymes. Synonyms: lerI (gene name). Enzyme Commission Number: EC 5.1.3.39. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5426; L-erythrulose 4-phosphate epimerase; EC 5.1.3.39; lerI (gene name). Cat No: EXWM-5426. | |
| Lesinurad | ?98% (HPLC). Group: Fluorescence/luminescence spectroscopy. | |
| Lesinurad | Lesinurad is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with K m values of 0.85 and 2 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RDEA594. CAS No. 878672-00-5. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15258. | |
| Lesinurad sodium | Lesinurad sodium is a URAT1 and OAT inhibitor, is determined to be a substrate for the kidney transporters OAT1 and OAT3 with K m values of 0.85 and 2 μM, respectively. Uses: Scientific research. Group: Signaling pathways. Alternative Names: RDEA-594 sodium. CAS No. 1151516-14-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 50 mg; 100 mg; 200 mg. Product ID: HY-15258A. | |
| Lesogaberan hydrochloride | Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABA B receptor agonist with an EC 50 of 8.6 nM for human recombinant GABA B receptor. The affinity ( K i s) of Lesogaberan hydrochloride for rat GABA B and GABA A receptors, as measured by displacement of [ 3 H]GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AZD-3355 hydrochloride. CAS No. 2925644-17-1. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg. Product ID: HY-10061B. | |
| Lesopitron dihydrochloride | Lesopitron dihydrochloride is a full and selective 5-HT 1A receptor agonist with IC 50 of 125 nM in rat hippocampal membranes. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E4424. CAS No. 132449-89-9. Pack Sizes: 1 mg. Product ID: HY-101609. | |
| Lestaurtinib | It is used for the treatment of pancreatic cancer and acute myelogenous leukaemia (AML). Group: Biochemicals. Alternative Names: (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3,2,1-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one;A 154475.0; CEP 701 ; KT 5555; SP 924. Grades: Highly Purified. CAS No. 111358-88-4. Pack Sizes: 500ug, 1mg, 2mg, 5mg. US Biological Life Sciences. | Worldwide |
| Lestaurtinib | Lesraurtinib, also known as CEP701, KT 5555, SP 924, is an orally bioavailable indolocarbazole derivative with antineoplastic properties. Lestaurtinib inhibits autophosphorylation of FMS-like tyrosine kinase 3 (FLT3), resulting in inhibition of FLT3 activity and induction of apoptosis in tumor cells that overexpress FLT3. Synonyms: CEP-701; KT-5555; SP 924; (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one. Grade: ≥98%. CAS No. 111358-88-4. Molecular formula: C26H21N3O4. Mole weight: 439.46. | |
| Lestaurtinib | Lestaurtinib (CEP-701) is an orally active and selective RPTKs (receptor protein tyrosine kinase) inhibitor, competitively inhibits ATP binding to the TrkA/B/C domain. Lestaurtinib inhibits RPTKs phosphorylation, with IC 50 s of 2, 25 and 0.9 nM for FLT3 , TrkA and JAK2 , respectively. Lestaurtinib induces apoptosis and cycle arrest, also can inhibit growth of tumor [1] [2] [3] [4] [5] [6]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CEP-701; KT-5555. CAS No. 111358-88-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-50867. | |
| LETC | LETC is an orally active α-synuclein (α-Syn) aggregation inhibitor with an EC 50 of 66 nM in transfected DH60.21 neuroblastoma cells. LETC can cross the blood-brain barrier. LETC can be used for the study of synucleinopathies [1]. Uses: Scientific research. Group: Signaling pathways. CAS No. 951131-13-8. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-163739. | |
| Leteprinim potassium | Leteprinim potassium (AIT-082), a purine analog, is a neuroprotective agent and cognitive enhancer. Leteprinim potassium is a hypoxanthine derivative neurotrophic agent. Leteprinim potassium can induce brain-derived neurotrophic factor (BDNF) mRNA production following spinal cord lesions, and nerve growth factor (NGF) mRNA production in basal forebrain. Leteprinim potassium reduces glutamate toxicity in cultured hippocampal neurons. Leteprinim potassium increases heme-oxygenase 1 and 2 mRNA levels that play role in cellular defense against reactive oxygen species [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AIT-082. CAS No. 192564-13-9. Pack Sizes: 5 mg. Product ID: HY-120251A. | |
| Leteprinim Potassium Salt | A synthetic purine derivative with neuroprotective effects. A cognitive enhancer, is transported into brain by a nonsaturable influx mechanism and out of brain by a saturable efflux mechanism. Group: Biochemicals. Alternative Names: 4- [ [3- (1, 6-Dihydro-6-oxo-9H-purin-9-yl) -1-oxopropyl] amino] benzoic Acid Potassium Salt; AIT 082; Neotrofin. Grades: Highly Purified. CAS No. 192564-13-9. Pack Sizes: 10mg. US Biological Life Sciences. | Worldwide |
| Letermovir | Letermovir (AIC246) is a potent inhibitor of CMV , which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. Uses: Scientific research. Group: Signaling pathways. Alternative Names: AIC246; MK-8228. CAS No. 917389-32-3. Pack Sizes: 10 mM * 1 mL; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-15233. | |
| L-Ethionine | L-Ethionine (L-ETH) is aamino acids and their derivatives. Uses: Scientific research. Group: Peptides. Alternative Names: L-ETH. CAS No. 13073-35-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-W017200. | |
| L-Ethionine | Ethionine is an antimetabolite and methionine antagonist. It also produces liver neoplasms. Uses: Ethionine-induced inhibition of protein synthesis and lowering of atp level in the liver. Synonyms: H-Eth-OH; (S)-2-Amino-4-(ethylthio)butanoic acid. Grade: 98%. CAS No. 13073-35-3. Molecular formula: C6H13NO2S. Mole weight: 163.24. | |
| L-Ethionine | L-Ethionine. Group: Biochemicals. Alternative Names: S-Ethyl-L-homocysteine. Grades: Highly Purified. CAS No. 13073-35-3. Pack Sizes: 500mg, 1g, 2g, 5g, 10g. Molecular Formula: C6H13NO2S. US Biological Life Sciences. | Worldwide |
| Letolizumab | Letolizumab (BMS-986004) is a monoclonal antibody targeting CD40L , which is produced to express mutant IgG1 lacking effector function, including Fc binding and complement fixation. Letolizumab reduces rejection, thromboembolism and prolongs the survival time [1] [2] [3]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: BMS-986004. CAS No. 1450981-87-9. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99701. | |
| Letosteine | Letosteine. Group: Biochemicals. Grades: Highly Purified. CAS No. 53943-88-7. Pack Sizes: 250mg, 500mg, 1g, 2g, 5g. US Biological Life Sciences. | Worldwide |
| Letosteine | Letosteine is an orally active, potent and safe expectorant. Letosteine has the effect of scavenging reactive oxygen species (ROS). Letosteine dissolves bronchial mucus and reduces respiratory inflammation symptoms, and restores gas exchanges and natural defense mechanisms in the lung. Letosteine can be used for acute or chronic respiratory diseases (such as bronchopneumopathies) research [1] [2] [3] [4]. Uses: Scientific research. Group: Signaling pathways. CAS No. 53943-88-7. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-107355. | |
| Letrazuril | Letrazuril is an anti-HIV agent. Uses: Designed for use in research and industrial production. Additional or Alternative Names: Letrazurilo, Letrazurilum, Letrazuril [INN], LETRAZURIL, Letrazurilum [INN-Latin], Letrazurilo [INN-Spanish], CID59745, (+-)-(2,6-Dichloro-4-(4,5-dihydro-3,5-dioxo-as-triazin-2(3H)-yl)phenyl)(p-fluorophenyl)acetonitrile, 103337-74-2. Product Category: Inhibitors. Appearance: Solid. CAS No. 103337-74-2. Molecular formula: C17H9Cl2FN4O2. Mole weight: 391.183 g/mol. Purity: 0.96. IUPACName: 2-[2,6-dichloro-4-(3,5-dioxo-1,2,4-triazin-2-yl)phenyl]-2-(4-fluorophenyl)acetonitrile. Canonical SMILES: C1=CC(=CC=C1C(C#N)C2=C(C=C(C=C2Cl)N3C(=O)NC(=O)C=N3)Cl)F. Density: 1.54g/cm³. Product ID: ACM103337742. Alfa Chemistry ISO 9001:2015 Certified. | |
| Letrozole | Letrozole (CGS 20267) is a potent, selective, reversible and orally active non-steroidal inhibitor of aromatase , with an IC 50 of 11.5 nM. Letrozole selective inhibits estrogen biosynthesis, and can be used for the research of breast cancer [1] [2] [3]. Uses: Scientific research. Group: Natural products. Alternative Names: CGS 20267. CAS No. 112809-51-5. Pack Sizes: 10 mM * 1 mL; 100 mg; 200 mg; 500 mg. Product ID: HY-14248. | |
| Letrozole | 1g Pack Size. Group: Bioactive Small Molecules, Research Organics & Inorganics. Formula: C17H11N5. CAS No. 112809-51-5. Prepack ID 36941533-1g. Molecular Weight 285.3. See USA prepack pricing. | |
| Letrozole | A nonsteroidal aromatase inhibitor structurally related to Fadrozole. Antineoplastic. An orally bioavailable non-steroidal triazole compound that acts as a potent and selective inhibitor of aromatase (IC50=140, 350 and 450pM in Dex-treated fibroblasts, MCF-7Ca, and JEG-3 cells, respectively). Competitively, but reversibly binds to the heme iron of aromatase. Does not affect the synthesis of adrenal mineralocorticoid or glucocorticoids. Reported to be highly effective as an anti-estrogenic and anti-proliferative agent in estrogen-rich tumors. Also delays the fusing of the growth plates in adolescents and enhances the effectiveness of growth hormone. Shown to synergistically induce apoptosis and cause tumor regression when combined with IGF-1R inhibitors. Group: Biochemicals. Alternative Names: 4, 4- (1H-1, 2, 4-Triazol-1-ylmethylene) bisbenzonitrile; 4-[1- (4-Cyanophenyl) -1- (1, 2, 4-triazol-1-yl) methyl]benzonitrile; CGS 20267; Femara; Lerozole; Letrazole; Aromatase Inhibitor II. Grades: Highly Purified. CAS No. 112809-51-5. Pack Sizes: 1g, 5g. Molecular Formula: C17H11N5, Molecular Weight: 285.3. US Biological Life Sciences. | Worldwide |
| Letrozole-d4 | A deuterated version of Letrozole, a nonsteroidal aromatase inhibitor structurally related to Fadrozole.The current lot is 84% d4, 16% d3, no detectable d2, d1 or d0. Group: Biochemicals. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| Letrozole-[d4] | Letrozole-[d4] is the labelled analogue of Letrozole, which is a nonsteroidal aromatase inhibitor structurally related to Fadrozole. Synonyms: Letrozole-d4; 4,4'-(1H-1,2,4-Triazol-1-ylmethylene)bisbenzonitrile-d4; 4-[1-(4-Cyanophenyl)-1-(1,2,4-triazol-1-yl)methyl]benzonitrile-d4; CGS 20267-d4; Femara-d4; Lerozole-d4; Letrazole-d4. Grade: ≥95%. CAS No. 1133712-96-5. Molecular formula: C17H7D4N5. Mole weight: 289.33. | |
| Letrozole EP Impurity B | Letrozole EP Impurity B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 113402-31-6. Molecular formula: C22H13N3. Mole weight: 319.37. Catalog: APB113402316. | |
| Letrozole Related Compound A | United States Pharmacopeia (USP) Reference Standard. Group: Pharmacopeia & metrological institutes standards. | |
| Leu14, Cys40, Exendin-4 | Leu14, Cys40, Exendin-4. Synonyms: His-Gly-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Leu-Ser-Lys-Gln-Leu-Glu-Glu-Glu-Ala-Val-Arg-Leu-Phe-Ile-Glu-Trp-Leu-Lys-Asn-Gly-Gly-Pro-Ser-Ser-Gly-Ala-Pro-Pro-Pro-Ser-Cys-NH2. Molecular formula: C188H289N51O61S. Mole weight: 4271.94. | |
| Leu-Ala-OH | This dipeptide inhibits ubiquitin-mediated protein degradation. Synonyms: L-Leucyl-L-alanine. Grade: ≥ 97% (HPLC). CAS No. 7298-84-2. Molecular formula: C9H18N2O3. Mole weight: 202.25. | |
| Leu-Ala-OH | Leu-Ala-OH. Group: Biochemicals. Alternative Names: L-Leucyl-L-alanine. Grades: Highly Purified. CAS No. 7298-84-2. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C9H18N2O3. US Biological Life Sciences. | Worldwide |
| Leu-Ala-OH ≥97% (HPLC) | Leu-Ala-OH ≥97% (HPLC). Group: Biochemicals. Grades: Reagent Grade. CAS No. 7298-84-2. Pack Sizes: 1g, 5g, 10g, 25g. US Biological Life Sciences. | Worldwide |
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