A directory of where to buy chemicals in the USA, including: distributors, industrial manufacturers, bulk supplies and wholesalers of raw ingredients & finished goods.
2,7-Dichloronorlichexanthone is a lichen chromone found in ascomycete licheniformis. Alternative Names: Glutaconic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester (8CI); 1-[(5-Hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] 3-methyl-2-pentenedioate; Fuciformic acid; 2-Pentenedioic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester. CAS No. 22399-41-3. Molecular formula: C18H18O8. Mole weight: 362.33.
Leprolomin
It is a novel diphenyl ether isolated from the lichen psoroma leprolomum. Alternative Names: Ethanone, 1-[6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl]-; 1-(6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl)ethan-1-one; NSC 646011. Grades: ≥98%. CAS No. 68984-67-8. Molecular formula: C20H22O8. Mole weight: 390.38.
Leptin (116-130) (human)
Leptin (116-130) (human) is a fragment of human leptin, which is an adipose tissue-derived protein encoded by an obesity gene and is involved in controlling food intake, energy expenditure and reproduction, as well as playing a role in immune regulation, inflammation, and hematopoiesis. Alternative Names: Obese Gene Peptide (116-130) (human); L-Serine, L-seryl-L-cysteinyl-L-histidyl-L-leucyl-L-prolyl-L-tryptophyl-L-alanyl-L-serylglycyl-L-leucyl-L-α-glutamyl-L-threonyl-L-leucyl-L-α-aspartyl-; H-Ser-Cys-His-Leu-Pro-Trp-Ala-Ser-Gly-Leu-Glu-Thr-Leu-Asp-Ser-OH; L-seryl-L-cysteinyl-L-histidyl-L-leucyl-L-prolyl-L-tryptophyl-L-alanyl-L-seryl-glycyl-L-leucyl-L-alpha-glutamyl-L-threonyl-L-leucyl-L-alpha-aspartyl-L-serine. Grades: ≥95%. CAS No. 2243207-12-5. Molecular formula: C70H106N18O24S. Mole weight: 1615.76.
Leptin (22-56), human
Leptin (22-56) (human) is the fragment of leptin, a hormone produced by the fat cells in human body. Alternative Names: H-Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH; L-valyl-L-prolyl-L-isoleucyl-L-glutaminyl-L-lysyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-alpha-aspartyl-L-threonyl-L-lysyl-L-threonyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-isoleucyl-L-valyl-L-threonyl-L-arginyl-L-isoleucyl-L-asparagyl-L-alpha-aspartyl-L-isoleucyl-L-seryl-L-histidyl-L-threonyl-L-glutaminyl-L-seryl-L-valyl-L-seryl-L-seryl-L-lysyl-L-glutaminyl-L-lysine. Grades: >95%. CAS No. 183598-56-3. Molecular formula: C171H298N50O56. Mole weight: 3950.49.
Leptin (22-56), human
Leptin (22-56), human is the fragment of leptin, mediated via several isoforms of receptors (Ob-Rs). Uses: Scientific research. Category: Signaling pathways. CAS No. 183598-56-3. Pack Sizes: 500 μg; 1 mg; 5 mg. Product ID: HY-P1523.
Leptin Fragment 116-130 Amide mouse
A synthetic leptin peptide fragment. Alternative Names: LEP 116-130. Grades: >95%. CAS No. 258276-95-8. Molecular formula: C64H109N19O24S. Mole weight: 1560.73.
Leptin (human)
Leptin (human) is a peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Alternative Names: 1: PN: WO0038651 SEQID: 1 unclaimed protein; 22-167-Protein (human gene obese 167-amino acid isoform precursor); Anti-obesity protein (human); Leptin (human clone 3 gene Ob); Leptin (human gene ob protein 146-amino acid fragment); Leptin (synthetic human mutant 15B); Protein (human gene ob active isoform). Grades: ≥95% by HPLC. CAS No. 177404-21-6.
Leptocillin is extracted from Leptoaphaeria sp. L-179. It is resistant to several Gram-positive bacteria (Staphylococcus aureus 209P, Bacillus subtilis No. 119) and several Gram-negative bacteria (Klebsiella pneumoniae 22 # 3038, proteus singular GN310). Alternative Names: Antibiotic MK4588; MK 4588; MK-4588; 7-(1-Isocyano-2-(4-methoxyphenyl))ethenyl-1-hydroxy-7-isocyanobicyclo(4,2,0)oct-2-en-4-one. CAS No. 123949-57-5. Molecular formula: C19H16N2O3. Mole weight: 320.34.
Leptofuranin A
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H48O5. Mole weight: 512.72.
Leptofuranin B
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H50O5. Mole weight: 526.75.
Leptofuranin C
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H46O5. Mole weight: 510.70.
Leptofuranin D
It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H48O5. Mole weight: 524.73.
Leptoglycin
Leptoglycin is an antibacterial peptide isolated from Leptodactylus pentadactylus. Leptoglycin was able to inhibit the growth of Gram-negative bacteria Pseudomonas aeruginosa, Escherichia coli and Citrobacter freundii with minimal inhibitory concentrations (MICs) of 8 microM, 50 microM, and 75 microM respectively, but it did not show antimicrobial activity against Gram-positive bacteria (Staphylococcus aureus, Micrococcus luteus and Enterococcus faecalis), yeasts (Candida albicans and Candida tropicalis) and dermatophytes fungi (Microsporum canis and Trichophyton rubrum). Alternative Names: Gly-Leu-Leu-Gly-Gly-Leu-Leu-Gly-Pro-Leu-Leu-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Leu-Leu.
Leptolstatin
It is produced by the strain of Str. sp. SAM1595. It has no activity against bacteria, fungi and yeast, in addition to Millet wine schizozoite yeast (MIC is 0.4 μg/mL). It has a strong inhibitory effect on mammalian cells, such as normal fibroblast 3Y1 cells in rats (IC50 is 0.4 ng/mL). Alternative Names: 2H-Pyran-2-one, 6-[(1E,3Z,5R,7E,9E,11R,13S,14R,15S,17E)-14,19-dihydroxy-3,5,9,11,13,15,17-heptamethyl-12-oxo-1,3,7,9,17-nonadecapentaen-1-yl]-5,6-dihydro-, (6R)-; (R)-6-((1E,3Z,5R,7E,9E,11R,13S,14R,15S,17E)-14,19-dihydroxy-3,5,9,11,13,15,17-heptamethyl-12-oxononadeca-1,3,7,9,17-pentaen-1-yl)-5,6-dihydro-2H-pyran-2-one. CAS No. 149633-91-0. Molecular formula: C31H46O5. Mole weight: 498.69.
Leptomycin A
a potent anti-fungal antibiotic. Leptomycin A is a highly specific inhibitor of export protein CRM1. Alternative Names: Leptomycin A;Jildamycin;87081-36-5;(2E,10E,12E,16E,18E)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-19-(3-methyl-6-oxo-2,3-dihydropyran-2-yl)-8-oxononadeca-2,10,12,16,18-pentaenoic acid;NSC 369326;NSC369326;ATS1287 A, LMA;SCHEMBL14190847;MFCD01711669;BS-1083;NSC-369326;19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-2,10,12,16,18-nonadecapentaenoic acid;2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-;2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-;DA-54856;NS00011727;Leptomycin A; Antibiotic ATS 1287A; Antibiotic PD 118607; Jildamycin;(2E,5S,6R,7S,9R,10E,12E,15R,16Z,18E)-6-Hydroxy-3,5,7,9,11,15,17-heptamethyl-19-[(2S,3S)-3-methyl-6-oxo-2,3-dihydropyran-2-yl]-8-oxononadeca-2,10,12,16,18-pentaenoic acid;2,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-6-hydroxy-3,5,7,9,11,15,17-heptamethyl-8-oxo-. Grades: >99% by HPLC. CAS No. 87081-36-5. Molecular formula: C12H14N2O3S. Mole weight: 266.32.
Leptomycin B
a potent anti-fungal antibiotic. Leptomycin B is an inhibitor of export protein CRM1. Alternative Names: 19-(3,6-Dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-17-ethyl-6-hydroxy-3,5,7,9,11,15-hexamethyl-8-oxo-2,10,12,16,18-Nonadecapentaenoic Acid; Elactocin; Mantuamycin; Antibiotic CI 940; PD 114720. CAS No. 87081-35-4. Molecular formula: C33H48O6. Mole weight: 540.73.
Leptomycin B
Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CI 940; LMB. CAS No. 87081-35-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-16909.
Leptomycin B (LMB)
Leptomycin B (LMB, CI 940, Elactocin, Mantuamycin, NSC 364372) is a potent antifungal antibiotic isolated from Streptomyces and acts as a specific inhibitor of the nuclear export factor CRM1. Leptomycin B rapidly induces cytotoxic effects in cancer cell lines via covalent inhibition of CRM1 with IC50 values of 0.1 nM-10 nM. Group: Inhibitors. Alternative Names: LMB, CI 940, Elactocin, Mantuamycin, NSC 364372. CAS No. 87081-35-4. Pack Sizes: 5mg. Product ID: S7580. Formula: C33H48O6. Storage Conditions: 3 years -20°C powder.
United States; Europe
Leptosin I
It is produced by the strain of I Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.13 μg/mL. Alternative Names: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (5alpha,6S,6'S,15alpha)-; (+)-Leptosin I; 22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2'',3'':2',3'][1,2,3,4,6]tetrathiazocino[6'',5'':1',5']pyrrolo[3',4':6,7]pyrazino[2''',1''':2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone,2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3a,5ab,10ba,10cS*,15ab,18b,22ab,22ba,23aa,24S*)-(+)-; Leptosine I. CAS No. 160472-96-8. Molecular formula: C32H32N6O7S4. Mole weight: 740.89.
Leptosin J
It is produced by the strain of J Leptosphaeria sp. OUPS-4. In order to understand its cytotoxic effects, someone tested Leukemia lymphocyte P388 in culture with an ED50 of 1.25 μg/mL. Alternative Names: Chaetocin, 2,5:2',5'-dide(epidithio)-19'-deoxy-2',5'-(epitetrathio)-5,6'-epoxy-6-hydroxy-19',19'-dimethyl-, (2alpha,5alpha,6S,6'S,15alpha)-; 22bH-18,22a-(Iminomethano)-10b,23a-methano-10bH,23aH-indolo[2'',3'':2',3'][1,2,3,4,6]tetrathiazocino[6'',5'':1',5']pyrrolo[3',4':6,7]pyrazino[2''',1''':2,3][1,3]oxazepino[4,5-b]indole-1,4,17,25(18H)-tetrone,2,3,5a,6,15,15a-hexahydro-24-hydroxy-3-(hydroxymethyl)-2,26-dimethyl-18-(1-methylethyl)-, (3a,5aa,10bb,10cR*,15aa,18a,22aa,22bb,23ab,24R*)-(+)-; Leptosine J. CAS No. 160550-15-2. Molecular formula: C32H32N6O7S4. Mole weight: 740.89.
Lepzacitinib
Lepzacitinib. CAS No. 2321488-47-3.
LEQ803
LEQ803 (N-Desmethyl Ribociclib) is a drug metabolite of the CDK4/6 inhibitor Ribociclib (HY-15777), which is produced through metabolism by CYP3A4. LEQ803 has potential application value in the field of oncology[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: N-Desmethyl Ribociclib. CAS No. 1211441-59-6. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-171459.
Lercanidipine
Lercanidipine is a third-generation, lipophilic, brain-penetrant, vascular-selective and orally active dihydropyridine-calcium channel blocker with a pIC50 of 7.74 (converts from μM). Lercanidipine has long lasting antihypertensive action as well as reno- and neuro-protective effect. Lercanidipine also shows anti-oxidant, anti-inflammatory and anti-apoptotic properties. Lercanidipine can be used in cardiovascular and neurological research[1][2][3][4][5]. Uses: Scientific research. Category: Signaling pathways. CAS No. 100427-26-7. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-B0612.
Lercanidipine-d3 Hydrochloride
A labeled dihydropyridine calcium channel blocker. Group: Biochemicals. Alternative Names: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)(methyl-d3)amino]-1,1-dimethylethyl Methyl Ester Hydrochloride. Grades: Highly Purified. Pack Sizes: 1mg. US Biological Life Sciences.
An impurity of Lercanidipine, which is a calcium channel blocker used primarily for the treatment of hypertension and angina. Alternative Names: 5-Ethyl-demethyl Lercanidipine Hydrochloride; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-ethyl ester hydrochloride; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, 3-[2-[(3,3-diphenylpropyl)methylamino]-1,1-dimethylethyl] 5-ethyl ester, hydrochloride (1:1); Lercanidipine EP Impurity D; 3-[1-[(3,3-Diphenylpropyl)(methyl)amino]-2-methylpropan-2-yl] 5-ethyl (4RS)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate hydrochloride. Grades: >95%. CAS No. 210579-71-8. Molecular formula: C37H44ClN3O6. Mole weight: 662.21.
Lercanidipine hydrochloride
Lercanidipine hydrochloride. CAS No. 100427-27-8. Product ID: ACM100427278. Molecular formula: C36H41N3O6.ClH. Mole weight: 648.196. Alfa Chemistry - ISO 9001:32057 Certified.
A dihydropyridine calcium channel blocker. Antihypertensive. Uses: The hydrochloride salt form of lercanidipine could be used as an antihypertensive agent through influencing the l-type ca2+ channel at some extent. Alternative Names: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic Acid 2-[(3,3-Diphenylpropyl)methylamino]-1,1-dimethylethyl Methyl Ester Hydrochloride. Grades: > 95%. CAS No. 132866-11-6. Molecular formula: C36H41N3O6·HCl. Mole weight: 648.19.
Lercanidipine Hydrochloride
Lercanidipine hydrochloride is a L-type (Cav1.2b) vascular channel antagonist; L-type (Cav1.2a) cardiac channel agonist voltage-dependent and highly lipophylic compound, which exhibits a slower onset and longer duration of action than other calcium channel antagonists; an antihypertensive agent in patients with mild-to-moderate hypertension; more vasoselective than lacidipine and amlodipine. Group: Biochemicals. Alternative Names: 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 2-[ (3, 3-diphenylpropyl) methylamino]-1, 1-dimethylethyl methyl ester hydrochloride; Cardiovasc; Carmen. Grades: Highly Purified. CAS No. 132866-11-6. Pack Sizes: 1g, 2g, 5g, 10g, 25g. Molecular Formula: C36H42ClN3O6. US Biological Life Sciences.
Worldwide
L-(+)-Ergothioneine
L-Ergothioneine is a natural molecule isolated from the rye ergot fungus and later identified in rat erythrocytes and liver and in numerous other animal tissues. Its antioxidizing properties may afford the compound therapeutic potential or it may be used as a food additive or in cosmetics. Group: Biochemicals. Alternative Names: (αS)-α-Carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-1H-imidazole-4-ethanaminium Inner Salt; 2-Mercaptohistidine Betaine; NSC 7175; 2-Mercapto-N,N-dimethylhistidine Methyl Ester Betaine; 2-Mercapto-histidine; Sympectothion; Thiasine; Thioneine; Thiotane. Grades: Highly Purified. CAS No. 497-30-3. Pack Sizes: 5mg, 10mg, 25mg. Molecular Formula: C?H??N?O?S, Molecular Weight: 229.3. US Biological Life Sciences.
Worldwide
L-(+)-Ergothioneine
L-(+)-Ergothioneine is a natural amino acid isolated from the rye ergot fungus and later identified in rat erythrocytes and the liver. L-(+)-Ergothioneine is an antioxidant and a unique cell physiological protective agent, which has many physiological functions such as scavenging free radicals, whitening, anti-aging, preventing ultraviolet radiation damage, maintaining DNA synthesis and normal cell growth. Alternative Names: 1H-Imidazole-4-ethanaminium, α-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-, inner salt, (αS)-; (2S)-3-(2-Sulfanyl-1H-imidazol-4-yl)-2-(trimethylazaniumyl)propanoate; (S)-5-(2-Carboxy-2-(trimethylammonio)ethyl)-1H-imidazole-2-thiolate; 1H-Imidazole-4-ethanaminium, α-carboxy-2,3-dihydro-N,N,N-trimethyl-2-thioxo-, inner salt, (S)-; 2-Mercapto-N,N-dimethylhistidine methyl ester betaine; 2-Mercaptohistidine betaine; 2-Mercaptohistidine trimethylbetaine; L-Ergothioneine; ErgoActive; Ergothioneine; Ergothionine; Histidine, 2-mercapto-, trimethylbetaine; Histidine, 2-mercapto-N,N-dimethyl-, betaine; L-(+)-Ergothionene; NSC 7175; Phytothioneine; Sympectothion; Thiasine; Thioneine; thiotaine; Thiotane. Grades: >95%. CAS No. 497-30-3. Molecular formula: C9H15N3O2S. Mole weight: 229.30.
L-(+)-Ergothioneine-[d3] is a stable isotope analogue of L-(+)-Ergothioneine. It is a natural molecule isolated from the rye ergot fungus and later identified in rat erythrocytes and liver and in numerous other animal tissues. Its antioxidizing properties may afford the compound therapeutic potential or it may be used as a food additive or in cosmetics. Alternative Names: (αS)-α-Carboxy-2,3-dihydro-N,N,-dimethyl-N-(methyl-d3)-2-thioxo-1H-imidazole-4-ethanaminium Inner Salt; 2-Mercaptohistidine-d3 Betaine; 2-Mercapto-N,N-dimethylhistidine Methyl Ester Betaine-d3; 2-Mercaptohistidine-d3; L-(+)-Ergothioneine D3. Grades: 95% by CP; 99% atom D. CAS No. 1356933-89-5. Molecular formula: C9H12D3N3O2S. Mole weight: 232.32.
L-(+)-Ergothioneine-d9
Labeled L-Ergothionine. It is a natural molecule isolated from the rye ergot fungus and later identified in rat erythrocytes and liver and in numerous other animal tissues. Its antioxidizing properties may afford the compound therapeutic potential or it may be used as a food additive or in cosmetics. Group: Biochemicals. Alternative Names: (αS)-α-Carboxy-2,3-dihydro-N,N,N-tri(methyl-d3)-2-thioxo-1H-imidazole-4-ethanaminium Inner Salt; 2-Mercaptohistidine Betaine-d9; NSC 7175-d9; 2-Mercapto-N,N-dimethylhistidine Methyl Ester Betaine-d9; 2-Mercapto-histidine-d9; Sympectothion-d9; Thiasine-d9; Thioneine-d9; Thiotane-d9. Grades: Highly Purified. CAS No. 497-30-3-unlabeled. Pack Sizes: 1mg. Molecular Formula: C?H?D?N?O?S, Molecular Weight: 238.35. US Biological Life Sciences.
Worldwide
L-Ergothioneine Powder
L-Ergothioneine Powder. Alternative Names: EGT. CAS No. 497-30-3. Product ID: DS497303. Molecular formula: C9H15N3O2S. Mole weight: 229.3 g/mol. Alfa Chemistry - ISO 9001:32057 Certified.
Leriglitazone
Leriglitazone (MIN-102; Hydroxypioglitazone) is an orally active and a BBB-penetrable PPARγ agonist with an EC50 of 9 μM. Leriglitazone, as a regulator of mitochondrial function, has neuroprotective, anti-inflammatory and antioxidant effects. Leriglitazone can be used in the study of neuroinflammatory and neurodegenerative diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MIN-102; Hydroxypioglitazone. CAS No. 146062-44-4. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117727.
Leriglitazone hydrochloride
Leriglitazone (MIN-102; Hydroxypioglitazone) hydrochloride is an orally active and a BBB-penetrable PPARγ agonist with an EC50 of 9 μM. Leriglitazone hydrochloride, as a regulator of mitochondrial function, has neuroprotective, anti-inflammatory and antioxidant effects. Leriglitazone hydrochloride can be used in the study of neuroinflammatory and neurodegenerative diseases[1][2][3][4]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: MIN-102 hydrochloride; Hydroxypioglitazone hydrochloride. CAS No. 146062-46-6. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-117727A.
Leritrelvir
Leritrelvir (RAY1216) is an orally active SARS-CoV-2 main protease slow-tight inhibitor with a Ki of 8.6 nM[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: RAY1216. CAS No. 2923310-64-7. Pack Sizes: 1 mg; 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-153121.
Lerociclib
Lerociclib (G1T38) is a potent and selective inhibitor of CDK4/6, with IC50s of 1 nM, 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: G1T38. CAS No. 1628256-23-4. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg. Product ID: HY-112272.
Lerociclib dihydrochloride
Lerociclib dihydrochloride (G1T38 dihydrochloride) is a potent and selective inhibitor of CDK4/CDK6, with IC50s of 1 nM and 2 nM for CDK4/CyclinD1 and CDK6/CyclinD3, respectively. Uses: Scientific research. Category: Signaling pathways. Alternative Names: G1T38 dihydrochloride. CAS No. 2097938-59-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-112272A.
Leronlimab
Leronlimab (PRO 140) is a humanized IgG4 anti-CCR5 monoclonal antibody. Leronlimab inhibits CCR5-mediated HIV-1 viral and lung metastasis in mouse tumor models. Leronlimab can be used for the research of HIV nonalcoholic steatohepatitis (NASH) and cancer[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: PRO 140. CAS No. 674782-26-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99697.
L-erythro-3,5-diaminohexanoate dehydrogenase
This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-NH2 group of donors with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is L-erythro-3,5-diaminohexanoate:NAD+ oxidoreductase (deaminating). This enzyme is also called L-3,5-diaminohexanoate dehydrogenase. This enzyme participates in lysine degradation. Group: Enzymes. Synonyms: L-3,5-diaminohexanoate dehydrogenase. Enzyme Commission Number: EC 1.4.1.11. CAS No. 37377-90-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-1444; L-erythro-3,5-diaminohexanoate dehydrogenase; EC 1.4.1.11; 37377-90-5; L-3,5-diaminohexanoate dehydrogenase. Cat No: EXWM-1444.
L-erythro-3-hydroxyaspartate aldolase
A pyridoxal-phosphate protein. The enzyme, purified from the bacterium Paracoccus denitrificans NCIMB 8944, is strictly specific for the L-erythro stereoisomer of 3-hydroxyaspartate. Different from EC 4.1.3.41, erythro-3-hydroxy-D-aspartate aldolase. Requires a divalent cation. Group: Enzymes. Synonyms: L-erythro-β-hydroxyaspartate aldolase; L-erythro-β-hydroxyaspartate glycine-lyase; erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase. Enzyme Commission Number: EC 4.1.3.14. CAS No. 37290-64-5. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-4900; L-erythro-3-hydroxyaspartate aldolase; EC 4.1.3.14; 37290-64-5; L-erythro-β-hydroxyaspartate aldolase; L-erythro-β-hydroxyaspartate glycine-lyase; erythro-3-hydroxy-Ls-aspartate glyoxylate-lyase. Cat No: EXWM-4900.
L-erythro-methylphenidate hydrochloride
L-erythro-methylphenidate hydrochloride. Group: Biochemicals. Alternative Names: (2S,2'R)-(-)-threo-methyl a-phenyl-a-(2-piperidyl)acetate hydrochloride. Grades: Highly Purified. CAS No. 40431-63-8. Pack Sizes: 1mg, 2mg, 5mg, 10mg. Molecular Formula: C14H20ClNO2. US Biological Life Sciences.
Worldwide
L-Erythrono-1,4-lactone
It is a potential α-glucosidase inhibitor. Alternative Names: L-Erythronic acid gamma-lactone; L-Erythronic acid, γ-lactone; (3S,4S)-3,4-Dihydroxydihydrofuran-2(3H)-one; L-Erythronolactone; L-Erythronic acid 1,4-lactone. Grades: >97%. CAS No. 23732-40-3. Molecular formula: C4H6O4. Mole weight: 118.09.
L-erythro-Penturonic acid, 4-deoxy-3-O-methyl-, gamma-lactone (9CI). CAS No. 110089-30-0. Product ID: ACM110089300. Molecular formula: C6H8O4. Alfa Chemistry - ISO 9001:32057 Certified.
L-Erythrose
L-Erythrose is an intriguing bioactive compound, acting as a prevalent precursor in therapeutic drug syntheses. Alternative Names: L-(+)-Erythrose; L-erythro-tetrose; Butanal, 2,3,4-trihydroxy-, (2S,3S)-. CAS No. 533-49-3. Molecular formula: C4H8O4. Mole weight: 120.10.
L-(+)-Erythrose
100mg Pack Size. Group: Carbohydrates, Sugars. Formula: C4H8O4. CAS No. 533-49-3. Prepack ID 74151304-100mg. Molecular Weight 120.1. See USA prepack pricing.
L-erythro Sphingosine
L-erythro Sphingosine is a synthetic stereoisomer of sphingosine (d18:1). It inhibits protein kinase C (PKC) in vitro (IC50 = 3.3 mol%). Alternative Names: L-erythro-C18-Sphingosine; (E,2R,3S)-2-aminooctadec-4-ene-1,3-diol. Grades: ≥98%. CAS No. 6036-75-5. Molecular formula: C18H37NO2. Mole weight: 299.49.
L-Erythrulose
L-Erythrulose is a prominent compound widely used in the cosmetic industry for its self-tanning properties. This colorless ketose sugar reacts with the amino acids in the skin's outermost layer to produce a natural, long-lasting tan, making it a sought-after ingredient in self-tanning lotions and sprays. Alternative Names: L-(+)-Erythrulose; (3S)-1,3,4-Trihydroxy-2-butanone; (S)-1,3,4-Trihydroxybutan-2-one; 2-Butanone, 1,3,4-trihydroxy-, (3S). CAS No. 533-50-6. Molecular formula: C4H8O4. Mole weight: 120.10.
L-erythrulose 1-phosphate isomerase
The enzyme, characterized from the pathogenic bacterium Brucella abortus, which causes brucellosis in livestock, participates in erythritol catabolism. Group: Enzymes. Synonyms: eryH (gene name). Enzyme Commission Number: EC 5.3.1.33. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5473; L-erythrulose 1-phosphate isomerase; EC 5.3.1.33; eryH (gene name). Cat No: EXWM-5473.
L-erythrulose 4-kinase
The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of L-threitol. Group: Enzymes. Synonyms: lerK (gene name). Enzyme Commission Number: EC 2.7.1.209. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-3044; L-erythrulose 4-kinase; EC 2.7.1.209; lerK (gene name). Cat No: EXWM-3044.
L-erythrulose 4-phosphate epimerase
The enzyme, characterized from the bacterium Mycobacterium smegmatis, participates in the degradation of L-threitol. Group: Enzymes. Synonyms: lerI (gene name). Enzyme Commission Number: EC 5.1.3.39. Storage: Store it at +4 ?C for short term. For long term storage, store it at -20 ?C?-80 ?C. Form: Liquid or lyophilized powder. EXWM-5426; L-erythrulose 4-phosphate epimerase; EC 5.1.3.39; lerI (gene name). Cat No: EXWM-5426.
Lesinurad
Lesinurad(RDEA594), once-daily inhibitor of URAT1, is a transporter in the kidney that regulates uric acid excretion from the body. Alternative Names: 2-[[5-Bromo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-yl]thio]acetic acid; RDEA 594; Zurampic; [[5-bromo-4-(4-cyclopropyl-1-naphthalenyl)-4H-1,2,4-triazol-3-yl]thio]-acetic Acid; Lesinida. Grades: >98%. CAS No. 878672-00-5. Molecular formula: C17H14BrN3O2S. Mole weight: 404.28.
Lesinurad
Used for treatment of gout. It has a role as a uricosuric drug. Category: Active pharmaceutical ingredients. Synonyms: RDEA594. RDEA 594. Zurampic. CAS No. 878672-00-5. Product ID: API878672005. Molecular formula: C17H14BrN3O2S. Mole weight: 404.3. EINECS: 689-245-8. SMILES: C1CC1C2=CC=C(C3=CC=CC=C23)N4C(=NN=C4Br)SCC(=O)O. Appearance: White to Off-white Solid.
Lesinurad Impurity 16
An intermediate of Lesinurad, a urate transporter inhibitor used for the treatment of high blood uric acid levels associated with gout. Alternative Names: Methyl 2-(5-broMo-4-(4-cyclopropylnaphthalen-1-yl)-4H-1,2,4-triazol-3-ylthio)acetate. Grades: > 95%. CAS No. 878671-99-9. Molecular formula: C18H16BrN3O2S. Mole weight: 418.32.
Lesogaberan hydrochloride
Lesogaberan (AZD-3355) hydrochloride is a potent and selective GABAB receptor agonist with an EC50 of 8.6 nM for human recombinant GABAB receptor. The affinity (Kis) of Lesogaberan hydrochloride for rat GABAB and GABAA receptors, as measured by displacement of [3H]GABA binding in brain membranes: 5.1 nM and 1.4 μM, respectively. Lesogaberan hydrochloride inhibits transient lower esophageal sphincter relaxation through a peripheral mode of action[1]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AZD-3355 hydrochloride. CAS No. 2925644-17-1. Pack Sizes: 10 mM * 1 mL in DMSO; 5 mg; 10 mg; 25 mg. Product ID: HY-10061B.
Lestaurtinib
Lestaurtinib (CEP-701) is an orally active and selective RPTKs (receptor protein tyrosine kinase) inhibitor, competitively inhibits ATP binding to the TrkA/B/C domain. Lestaurtinib inhibits RPTKs phosphorylation, with IC50s of 2, 25 and 0.9 nM for FLT3, TrkA and JAK2, respectively. Lestaurtinib induces apoptosis and cycle arrest, also can inhibit growth of tumor[1][2][3][4][5][6]. Uses: Scientific research. Category: Signaling pathways. Alternative Names: CEP-701; KT-5555. CAS No. 111358-88-4. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg. Product ID: HY-50867.
Lestaurtinib
It is used for the treatment of pancreatic cancer and acute myelogenous leukaemia (AML). Group: Biochemicals. Alternative Names: (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3,2,1-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one;A 154475.0; CEP 701 ; KT 5555; SP 924. Grades: Highly Purified. CAS No. 111358-88-4. Pack Sizes: 500ug, 1mg, 2mg, 5mg. US Biological Life Sciences.
Worldwide
Lestaurtinib
Lesraurtinib, also known as CEP701, KT 5555, SP 924, is an orally bioavailable indolocarbazole derivative with antineoplastic properties. Lestaurtinib inhibits autophosphorylation of FMS-like tyrosine kinase 3 (FLT3), resulting in inhibition of FLT3 activity and induction of apoptosis in tumor cells that overexpress FLT3. Alternative Names: CEP-701; KT-5555; SP 924; (9S,10S,12R)-2,3,9,10,11,12-Hexahydro-10-hydroxy-10-(hydroxymethyl)-9-methyl-9,12-epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocin-1-one. Grades: ≥98%. CAS No. 111358-88-4. Molecular formula: C26H21N3O4. Mole weight: 439.46.
Leteprinim Potassium Salt
A synthetic purine derivative with neuroprotective effects. A cognitive enhancer, is transported into brain by a nonsaturable influx mechanism and out of brain by a saturable efflux mechanism. Group: Biochemicals. Alternative Names: 4- [ [3- (1, 6-Dihydro-6-oxo-9H-purin-9-yl) -1-oxopropyl] amino] benzoic Acid Potassium Salt; AIT 082; Neotrofin. Grades: Highly Purified. CAS No. 192564-13-9. Pack Sizes: 10mg. US Biological Life Sciences.
Worldwide
Letermovir
Letermovir is a novel anti-CMV compound which targets the pUL56 (amino acid 230-370) subunit of the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. It has a novel mode of action targets the enzyme UL56 terminase and keep active to other drug-resistant virus. It has been approved in prophylaxis of CMV infection and disease in adult CMV-seropositive recipients of an allogeneic hematopoietic stem cell transplant (HSCT). Uses: Antiviral agents. Alternative Names: AIC246; AIC-246; AIC 246; MK-8828; MK 8828; MK8828. Grades: ≥98%. CAS No. 917389-32-3. Molecular formula: C29H28F4N4O4. Mole weight: 572.56.
Letermovir
Letermovir (AIC246) is a potent inhibitor of CMV, which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors. Uses: Scientific research. Category: Signaling pathways. Alternative Names: AIC246; MK-8228. CAS No. 917389-32-3. Pack Sizes: 10 mM * 1 mL in DMSO; 1 mg; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg; 500 mg. Product ID: HY-15233.
Letermovir impurity 10
Letermovir impurity 10. Uses: For analytical and research use. Molecular formula: C32H32F2N4O5. Mole weight: 590.63. Catalog: APB11703.
Letermovir Impurity 11
Letermovir Impurity 11. Uses: For analytical and research use. Alternative Names: phenyl (2-fluorophenyl)carbamate. Molecular formula: C13H10FNO2. Mole weight: 231.07. Catalog: APB01520.
Letermovir impurity 12
Letermovir impurity 12. Uses: For analytical and research use. Molecular formula: C14H16FNO4. Mole weight: 281.28. Catalog: APB11737.
Letermovir impurity 13
Letermovir impurity 13. Uses: For analytical and research use. Molecular formula: C22H22F4N4O3. Mole weight: 466.44. Catalog: APB11738.