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| Product | Description | |
|---|---|---|
| Lenvatinib Impurity 53 | Lenvatinib Impurity 53. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4-amino-7-methoxyquinoline-6-carboxamide. Molecular Formula: C11H11N3O2. Mole Weight: 217.22. Catalog: APB01541. |  |
| Lenvatinib Impurity 54 | Lenvatinib Impurity 54. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H23Cl2N5O4. Mole Weight: 540.4. Catalog: APB08381. | |
| Lenvatinib Impurity 55 | Lenvatinib Impurity 55. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H21Cl2N5O3. Mole Weight: 498.36. Catalog: APB08382. | |
| Lenvatinib Impurity 56 | Lenvatinib Impurity 56. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C26H23Cl2N5O5. Mole Weight: 556.4. Catalog: APB08384. | |
| Lenvatinib Impurity 57 | Lenvatinib Impurity 57. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C24H20ClN5O4. Mole Weight: 477.91. Catalog: APB08383. | |
| Lenvatinib Impurity 58 | Lenvatinib Impurity 58. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2264050-65-7. Molecular Formula: C21H15D4ClN4O4. Mole Weight: 430.88. Catalog: APB2264050657. | |
| Lenvatinib Impurity 59 | Lenvatinib Impurity 59. Uses: For analytical and research use. Group: Impurity standards. CAS No. 796848-80-1. Molecular Formula: C13H10ClNO3. Mole Weight: 263.68. Catalog: APB796848801. | |
| Lenvatinib Impurity 59 | Lenvatinib Impurity 59. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 2,4-dichloro-7-methoxyquinoline-6-carboxamide. CAS No. 2241758-00-7. Molecular Formula: C11H8Cl2N2O2. Mole Weight: 270.00. Catalog: APB2241758007. | |
| Lenvatinib Impurity 60 | Lenvatinib Impurity 60. Uses: For analytical and research use. Group: Impurity standards. Alternative Names: 4,8-dichloro-7-methoxyquinoline-6-carboxamide. CAS No. 2713130-46-0. Molecular Formula: C11H8Cl2N2O2. Mole Weight: 270.00. Catalog: APB2713130460. | |
| Lenvatinib Impurity 78 | Lenvatinib Impurity 78. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2380197-89-5. Molecular Formula: C17H14ClN3O3. Mole Weight: 343.77. Catalog: APB2380197895. | |
| Lenvatinib Impurity 8 | Lenvatinib Impurity 8. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1882873-21-3. Molecular Formula: C21H17ClN4O3. Mole Weight: 408.84. Catalog: APB1882873213. | |
| Lenvatinib Impurity D | Lenvatinib Impurity D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 417717-04-5. Molecular Formula: C20H17ClN4O4. Mole Weight: 412.83. Catalog: APB417717045. | |
| Lenvatinib Impurity E | Lenvatinib Impurity E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 417717-20-5. Molecular Formula: C22H20ClN3O5. Mole Weight: 441.87. Catalog: APB417717205. | |
| Lenvatinib Impurity F | Lenvatinib Impurity F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 417717-21-6. Molecular Formula: C21H18ClN3O5. Mole Weight: 427.84. Catalog: APB417717216. | |
| Lenvatinib Impurity LFS-A | Lenvatinib Impurity LFS-A. Uses: For analytical and research use. Group: Impurity standards. CAS No. 796848-79-8. Molecular Formula: C10H11ClN2O2. Mole Weight: 226.66. Catalog: APB796848798. | |
| Lenvatinib Impurity LFS-B | Lenvatinib Impurity LFS-B. Uses: For analytical and research use. Group: Impurity standards. CAS No. 417721-36-9. Molecular Formula: C11H9ClN2O2. Mole Weight: 236.66. Catalog: APB417721369. | |
| Lenvatinib Impurity LFS-C | Lenvatinib Impurity LFS-C. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2143930-76-9. Molecular Formula: C20H19ClN4O4. Mole Weight: 414.85. Catalog: APB2143930769. | |
| Lenvatinib Impurity LFS-D | Lenvatinib Impurity LFS-D. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2143930-77-0. Molecular Formula: C13H14N2O3. Mole Weight: 246.27. Catalog: APB2143930770. | |
| Lenvatinib Impurity LFS-E | Lenvatinib Impurity LFS-E. Uses: For analytical and research use. Group: Impurity standards. CAS No. 417714-14-8. Molecular Formula: C21H20N4O4. Mole Weight: 392.42. Catalog: APB417714148. | |
| Lenvatinib Impurity LFS-F | Lenvatinib Impurity LFS-F. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2110414-05-4. Molecular Formula: C11H10N2O3. Mole Weight: 218.21. Catalog: APB2110414054. | |
| Lenvatinib Impurity LFS-G | Lenvatinib Impurity LFS-G. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2613141-84-5. Molecular Formula: C31H29ClN6O6. Mole Weight: 617.06. Catalog: APB2613141845. | |
| Lenvatinib Impurity LFS-H | Lenvatinib Impurity LFS-H. Uses: For analytical and research use. Group: Impurity standards. CAS No. 417722-93-1. Molecular Formula: C17H14ClN3O3. Mole Weight: 343.77. Catalog: APB417722931. | |
| Lenvatinib Impurity LFS-I | Lenvatinib Impurity LFS-I. Uses: For analytical and research use. Group: Impurity standards. CAS No. 2143930-75-8. Molecular Formula: C35H26Cl2N6O7. Mole Weight: 713.53. Catalog: APB2143930758. | |
| Lenvatinib Impurity LFS-J | Lenvatinib Impurity LFS-J. Uses: For analytical and research use. Group: Impurity standards. CAS No. 1788901-86-9. Molecular Formula: C21H19ClN4O5. Mole Weight: 442.86. Catalog: APB1788901869. | |
| Lenvatinib Impurity LFS-K | Lenvatinib Impurity LFS-K. Uses: For analytical and research use. Group: Impurity standards. CAS No. 417719-51-8. Molecular Formula: C18H15ClN4O4. Mole Weight: 386.79. Catalog: APB417719518. | |
| Lenvatinib Impurity LFS-L | Lenvatinib Impurity LFS-L. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C17H14N2O3. Mole Weight: 294.31. Catalog: APB08365. | |
| Lenvatinib Impurity LFS-M | Lenvatinib Impurity LFS-M. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C19H16ClN3O5. Mole Weight: 401.8. Catalog: APB08367. | |
| Lenvatinib Impurity LFZZ-8 | Lenvatinib Impurity LFZZ-8. Uses: For analytical and research use. Group: Impurity standards. Molecular Formula: C44H40Cl2N8O8. Mole Weight: 879.75. Catalog: APB08366. | |
| Lenvatinib Liposome | Lenvatinib is a type I tyrosine kinase inhibitor that exhibits potent anti-angiogenic activity in cancer therapy. This product is a pre-formulated liposome encapsulating Lenvatinib. It is only for research purposes. Group: Drug-loaded liposome. Categories: Niosomes, ethosomes, and transfersomes. |  |
| Lenvatinib mesylate | Lenvatinib mesylate (E7080 mesylate), an oral, multi-targeted tyrosine kinase inhibitor that inhibits VEGFR1-3 , FGFR1-4 , PDGFR , KIT , and RET , shows potent antitumor activities [1] [2]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: E7080 mesylate. CAS No. 857890-39-2. Pack Sizes: 10 mM * 1 mL; 25 mg; 50 mg; 100 mg. Product ID: HY-10981A. |  |
| Lenvatinib Methanesulfonate | Lenvatinib Methanesulfonate. Uses: For analytical and research use. Group: Impurity standards. CAS No. 857890-39-2. Molecular Formula: C22H23ClN4O7S. Mole Weight: 522.96. Catalog: APB857890392. | |
| Lenvatinib N-Oxide | One of the impurities of Lenvatinib. Lenvatinib is a multi-target inhibitor, mostly for VEGFR2(KDR)/VEGFR3(Flt-4) with IC50 of 4 nM/5.2 nM, less potent against VEGFR1/Flt-1, ~10-fold more selective for VEGFR2/3 against FGFR1, PDGFRα/&beta. Synonyms: 6-Carbamoyl-4-(3-chloro-4-(3-cyclopropylureido)phenoxy)-7-methoxyquinoline 1-Oxide; 4-[3-Chloro-4-[[ (cyclopropylamino) carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide 1-Oxide; Lenvatinib Impurity 10. CAS No. 1788901-86-9. Molecular formula: C21H19ClN4O5. Mole weight: 442.85. |  |
| Lenvervimab | Lenvervimab (GC1102) is a IgG1-type recombinant human hepatitis B Immunoglobulin. Lenvervimab can be used for research of hepatitis B virus infection [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: GC1102. CAS No. 2055006-79-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99693. | |
| Lenzilumab | Lenzilumab (KB 003) is a human monoclonal antibody targeting CSF2/GM-CSF for COVID-19, chronic myelomonocytic leukemia (CMML) and juvenile myelomonocytic leukemia (JMML) studies [1] [2]. Uses: Scientific research. Group: Inhibitory antibodies. Alternative Names: KB 003. CAS No. 1229575-09-0. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-P99207. | |
| Lenzilumab | Lenzilumab is a humanized monoclonal antibody targeting colony stimulating factor 2 (CSF2)/granulocyte-macrophage colony stimulating factor (GM-CSF). Lenzilumab has the potential for the treatment of COVID-19. Synonyms: KB 003; KB003; KB-003. CAS No. 1229575-09-0. | |
| LEO29102 | LEO29102 is a potent, selective, and soft-drug phosphodiesterase 4 (PDE4) inhibitor. It shows properties suitable for patient-friendly formulations giving efficient drug delivery to the skin. It may be useful for treatment of dermatological diseases and atopic dermatitis. It was developed by Neochem Pharmaceutical and in clinic phase 2 trials. Uses: Leo29102 may be useful for treatment of dermatological diseases and atopic dermatitis. Synonyms: LEO-29102; LEO 29102; LEO29102. 2-(6-(2-(3,5-dichloropyridin-4-yl)acetyl)-2,3-dimethoxyphenoxy)-N-propylacetamide. Grades: >98 %. CAS No. 1035572-38-3. Molecular formula: C20H22Cl2N2O5. Mole weight: 441.31. | |
| Leonurine | Leonurine is an alkaloid isolated from Leonurus artemisia , with anti-oxidative and anti-inflammatory. Uses: Scientific research. Group: Natural products. Alternative Names: SCM-198. CAS No. 24697-74-3. Pack Sizes: 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0741. | |
| Leonurine | Leonurine. Group: Biochemicals. Alternative Names: 4-Guanidinobutyl syringate. Grades: Plant Grade. CAS No. 24697-74-3. Pack Sizes: 20mg. Molecular Formula: C14H21N3O5, Molecular Weight: 311.334. US Biological Life Sciences. |  Worldwide |
| Leonurine hydrochloride | Leonurine hydrochloride is an alkaloid isolated from Leonurus artemisia , with anti-oxidative and anti-inflammatory. Uses: Scientific research. Group: Natural products. Alternative Names: SCM-198 hydrochloride. CAS No. 24735-18-0. Pack Sizes: 10 mM * 1 mL; 5 mg; 10 mg; 25 mg; 50 mg; 100 mg. Product ID: HY-N0741A. | |
| Leonurine Hydrochloride | Leonurine Hydrochloride. Group: Biochemicals. Grades: Plant Grade. CAS No. 24735-18-0. Pack Sizes: 20mg. Molecular Formula: C14H22ClN3O5, Molecular Weight: 347.8. US Biological Life Sciences. | Worldwide |
| LEP (116-130) (mouse) | LEP (116-130) (mouse). Group: Biochemicals. Grades: Purified. CAS No. 258276-95-8. Pack Sizes: 1mg. US Biological Life Sciences. | Worldwide |
| LEP (116-130) (mouse) TFA | LEP (116-130) (mouse) TFA is a synthetic leptin peptide fragment. Synonyms: Leptin Fragment 116-130 Amide mouse TFA; LEP(116-130) (mouse) TFA; H-Ser-Cys-Ser-Leu-Pro-Gln-Thr-Ser-Gly-Leu-Gln-Lys-Pro-Glu-Ser-NH2.TFA; L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-seryl-glycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-alpha-glutamyl-L-serinamide trifluoroacetic acid; L-Serinamide, L-seryl-L-cysteinyl-L-seryl-L-leucyl-L-prolyl-L-glutaminyl-L-threonyl-L-serylglycyl-L-leucyl-L-glutaminyl-L-lysyl-L-prolyl-L-α-glutamyl-, 2,2,2-trifluoroacetate (1:1). Grades: ≥95%. CAS No. 2828433-16-3. Molecular formula: C66H110F3N19O26S. Mole weight: 1674.77. | |
| Lepidine (4-Methylquinoline) | 25g Pack Size. Group: Building Blocks, Organics, Stains & Indicators. Formula: C10H9N. CAS No. 491-35-0. Prepack ID 40487028-25g. Molecular Weight 143.19. See USA prepack pricing. |  |
| Lepidocrocite | Heterocyclic Organic Compound. CAS No. 12022-37-6. Catalog: ACM12022376. |  |
| Lepimectin A4 | Lepimectin A4 is a component of the insecticide lepimectin and a synthetic macrocyclic lactone. Synonyms: (6R,13R,25R)-5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-13-[[(methoxyimino)phenylacetyl]oxy]-milbemycin B. Grades: >95% by HPLC. CAS No. 171249-05-1. Molecular formula: C41H53NO10. Mole weight: 719.86. | |
| L-(-)-Epinephrine | Endogenous catcholamine with combined α-and β-agonist activity. Principal sympathomimetic hormone produced by the adrenal medulla. Bronchodilator; cardiostimulant; mydriatic; antiglaucoma. Group: Biochemicals. Alternative Names: 4-[(1R)-1-Hydroxy-2-(methylamino)ethyl]-1,2-benzenediol; (R)-Epinephrine; Renoform; Renostypticin; Adnephrine; Adrenal; Adrenalin; Adrenaline; l-Epinephrine; Levoepinephrine. Grades: Highly Purified. CAS No. 51-43-4. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| L-(-)-Epinephrine-(+)-bitartrate (1-(3,4-Dihydroxyphenyl)-2-(methylamino)ethanol) | a,b-Adrenergic receptor agonist. Has positive chronotropic and inotropic effects on heart muscle. Activates adenylate cyclase to generate cAMP from ATP. Group: Biochemicals. Grades: Highly Purified. CAS No. 51-42-3. Pack Sizes: 100mg. US Biological Life Sciences. | Worldwide |
| L-(-)-Epinephrine-d3 | 2H Labeled Compounds. CAS No. 1217733-17-9. Molecular formula: C9H10D3NO3. Mole weight: 186.22. Catalog: ACM1217733179. | |
| L-(-)-Epinephrine-d3 | Endogenous catcholamine with combined α-and β-agonist activity. Principal sympathomimetic hormone produced by the adrenal medulla. Bronchodilator; cardiostimulant; mydriatic; antiglaucoma. Group: Biochemicals. Alternative Names: 4-[(1R)-1-Hydroxy-2-(methylamino-d3)ethyl]-1,2-benzenediol; (R)-Epinephrine-d3; Renoform-d3; Renostypticin-d3; Adnephrine-d3; Adrenal-d3; Adrenalin-d3; Adrenaline-d3; l-Epinephrine-d3; Levoepinephrine-d3. Grades: Highly Purified. Pack Sizes: 2.5mg. US Biological Life Sciences. | Worldwide |
| Lepirudin | Heterocyclic Organic Compound. CAS No. 120993-53-5. Molecular formula: C287H440N80O110S6. Density: g/cm³. Catalog: ACM120993535. | |
| Lepirudin | Lepirudin is an anticoagulant that acts as a direct thrombin inhibitor. Lepirudin binds to both free and clot-bound thrombin. Lepirudin is approved for the treatment of heparin-induced thrombocytopenia (HIT). Uses: The treatment of heparin-induced thrombocytopenia (hit). Synonyms: (Leu1,Thr2)-Hirudin (desulfated); Lepirudin; Refludan; Refludin; Hbw 023; Hbw-023; Hbw023. CAS No. 138068-37-8. Molecular formula: C287H440N80O111S6. Mole weight: 6979.41. | |
| Leprapinic acid | Leprapinic acid is a member of methoxybenzenes. Synonyms: Leprapic acid; methyl (E)-2-(3-hydroxy-5-oxo-4-phenylfuran-2(5H)-ylidene)-2-(2-methoxyphenyl)acetate; Benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-methoxy-, methyl ester, (E)-; α-[(2E)-3-Hydroxy-5-oxo-4-phenyl-2,5-dihydrofuran-2-ylidene]-2-methoxybenzeneacetic acid methyl ester; Benzeneacetic acid, α-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene)-2-methoxy-, methyl ester, (αE)-; [3-Hydroxy-5-oxo-4-phenyl-5H-furan-(2E)-ylidene]-(2-methoxy-phenyl)-acetic acid methyl ester. CAS No. 481-59-4. Molecular formula: C20H16O6. Mole weight: 352.34. | |
| Leprapinic acid methyl ether | Synonyms: Benzeneacetic acid, 2-methoxy-α-(3-methoxy-5-oxo-4-phenyl-2(5H)-furanylidene)-, methyl ester, (E)-. CAS No. 22628-25-7. Molecular formula: C21H18O6. Mole weight: 366.36. | |
| Lepraric acid | 2,7-Dichloronorlichexanthone is a lichen chromone found in ascomycete licheniformis. Synonyms: Glutaconic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester (8CI); 1-[(5-Hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] 3-methyl-2-pentenedioate; Fuciformic acid; 2-Pentenedioic acid, 3-methyl-, 1-[(5-hydroxy-7-methoxy-2-methyl-4-oxo-4H-1-benzopyran-6-yl)methyl] ester. CAS No. 22399-41-3. Molecular formula: C18H18O8. Mole weight: 362.33. | |
| Leprolomin | It is a novel diphenyl ether isolated from the lichen psoroma leprolomum. Synonyms: Ethanone, 1-[6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl]-; 1-(6-(3-acetyl-2,6-dihydroxy-4-methoxy-5-methylphenoxy)-2-hydroxy-4-methoxy-3-methylphenyl)ethan-1-one; NSC 646011. Grades: ≥98%. CAS No. 68984-67-8. Molecular formula: C20H22O8. Mole weight: 390.38. | |
| Leptin (116-130) (human) | Leptin (116-130) (human) is a fragment of human leptin, which is an adipose tissue-derived protein encoded by an obesity gene and is involved in controlling food intake, energy expenditure and reproduction, as well as playing a role in immune regulation, inflammation, and hematopoiesis. Synonyms: Obese Gene Peptide (116-130) (human); L-Serine, L-seryl-L-cysteinyl-L-histidyl-L-leucyl-L-prolyl-L-tryptophyl-L-alanyl-L-serylglycyl-L-leucyl-L-α-glutamyl-L-threonyl-L-leucyl-L-α-aspartyl-; H-Ser-Cys-His-Leu-Pro-Trp-Ala-Ser-Gly-Leu-Glu-Thr-Leu-Asp-Ser-OH; L-seryl-L-cysteinyl-L-histidyl-L-leucyl-L-prolyl-L-tryptophyl-L-alanyl-L-seryl-glycyl-L-leucyl-L-alpha-glutamyl-L-threonyl-L-leucyl-L-alpha-aspartyl-L-serine. Grades: ≥95%. CAS No. 2243207-12-5. Molecular formula: C70H106N18O24S. Mole weight: 1615.76. | |
| Leptin (22-56), human | Leptin (22-56) (human) is the fragment of leptin, a hormone produced by the fat cells in human body. Synonyms: H-Val-Pro-Ile-Gln-Lys-Val-Gln-Asp-Asp-Thr-Lys-Thr-Leu-Ile-Lys-Thr-Ile-Val-Thr-Arg-Ile-Asn-Asp-Ile-Ser-His-Thr-Gln-Ser-Val-Ser-Ser-Lys-Gln-Lys-OH; L-valyl-L-prolyl-L-isoleucyl-L-glutaminyl-L-lysyl-L-valyl-L-glutaminyl-L-alpha-aspartyl-L-alpha-aspartyl-L-threonyl-L-lysyl-L-threonyl-L-leucyl-L-isoleucyl-L-lysyl-L-threonyl-L-isoleucyl-L-valyl-L-threonyl-L-arginyl-L-isoleucyl-L-asparagyl-L-alpha-aspartyl-L-isoleucyl-L-seryl-L-histidyl-L-threonyl-L-glutaminyl-L-seryl-L-valyl-L-seryl-L-seryl-L-lysyl-L-glutaminyl-L-lysine. Grades: >95%. CAS No. 183598-56-3. Molecular formula: C171H298N50O56. Mole weight: 3950.49. | |
| Leptin Fragment 116-130 Amide mouse | A synthetic leptin peptide fragment. Synonyms: LEP 116-130. Grades: >95%. CAS No. 258276-95-8. Molecular formula: C64H109N19O24S. Mole weight: 1560.73. | |
| Leptin (human) | Leptin (human) is a peptide hormone secreted from white adipocytes and implicated in the regulation of food intake and energy balance. Synonyms: 1: PN: WO0038651 SEQID: 1 unclaimed protein; 22-167-Protein (human gene obese 167-amino acid isoform precursor); Anti-obesity protein (human); Leptin (human clone 3 gene Ob); Leptin (human gene ob protein 146-amino acid fragment); Leptin (synthetic human mutant 15B); Protein (human gene ob active isoform). Grades: ≥95% by HPLC. CAS No. 177404-21-6. | |
| Leptocillin | Leptocillin is extracted from Leptoaphaeria sp. L-179. It is resistant to several Gram-positive bacteria (Staphylococcus aureus 209P, Bacillus subtilis No. 119) and several Gram-negative bacteria (Klebsiella pneumoniae 22 # 3038, proteus singular GN310). Synonyms: Antibiotic MK4588; MK 4588; MK-4588; 7-(1-Isocyano-2-(4-methoxyphenyl))ethenyl-1-hydroxy-7-isocyanobicyclo(4,2,0)oct-2-en-4-one. CAS No. 123949-57-5. Molecular formula: C19H16N2O3. Mole weight: 320.34. | |
| Leptofuranin A | It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H48O5. Mole weight: 512.72. | |
| Leptofuranin B | It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H50O5. Mole weight: 526.75. | |
| Leptofuranin C | It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C32H46O5. Mole weight: 510.70. | |
| Leptofuranin D | It is produced by the strain of Str. tanashiensis. At low concentrations, it causes the stagnation of normal cells, but it can cause the death of transformed cells. Molecular formula: C33H48O5. Mole weight: 524.73. | |
| Leptoglycin | Leptoglycin is an antibacterial peptide isolated from Leptodactylus pentadactylus. Leptoglycin was able to inhibit the growth of Gram-negative bacteria Pseudomonas aeruginosa, Escherichia coli and Citrobacter freundii with minimal inhibitory concentrations (MICs) of 8 microM, 50 microM, and 75 microM respectively, but it did not show antimicrobial activity against Gram-positive bacteria (Staphylococcus aureus, Micrococcus luteus and Enterococcus faecalis), yeasts (Candida albicans and Candida tropicalis) and dermatophytes fungi (Microsporum canis and Trichophyton rubrum). Synonyms: Gly-Leu-Leu-Gly-Gly-Leu-Leu-Gly-Pro-Leu-Leu-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Gly-Leu-Leu. | |
| Leptolstatin | It is produced by the strain of Str. sp. SAM1595. It has no activity against bacteria, fungi and yeast, in addition to Millet wine schizozoite yeast (MIC is 0.4 μg/mL). It has a strong inhibitory effect on mammalian cells, such as normal fibroblast 3Y1 cells in rats (IC50 is 0.4 ng/mL). Synonyms: 2H-Pyran-2-one, 6-[(1E, 3Z, 5R, 7E, 9E, 11R, 13S, 14R, 15S, 17E)-14, 19-dihydroxy-3, 5, 9, 11, 13, 15, 17-heptamethyl-12-oxo-1, 3, 7, 9, 17-nonadecapentaen-1-yl]-5, 6-dihydro-, (6R)-; (R)-6-((1E, 3Z, 5R, 7E, 9E, 11R, 13S, 14R, 15S, 17E)-14, 19-dihydroxy-3, 5, 9, 11, 13, 15, 17-heptamethyl-12-oxononadeca-1, 3, 7, 9, 17-pentaen-1-yl)-5, 6-dihydro-2H-pyran-2-one. CAS No. 149633-91-0. Molecular formula: C31H46O5. Mole weight: 498.69. | |
| Leptomycin A | a potent anti-fungal antibiotic. Leptomycin A is a highly specific inhibitor of export protein CRM1. Synonyms: Jildamycin; Antibiotic ATS 1287A; Antibiotic PD 118607; 2,10,12,16,18-Nonadecapentaenoic acid, 19-(3,6-dihydro-3-methyl-6-oxo-2H-pyran-2-yl)-3,5,7,9,11,15,17-heptamethyl-6-hydroxy-8-oxo-. Grades: >99% by HPLC. CAS No. 87081-36-5. Molecular formula: C32H46O6. Mole weight: 526.71. | |
| Leptomycin A (Antibiotic ATS 1287A, Antibiotic PD 118607, Jildamycin) | Leptomycin A, a methyl (cf. ethyl) analogue of Leptomycin B, is a minor component of the leptomycin complex produced by selected Streptomyces species. Leptomycin B is a potent inhibitor of the nuclear transport receptor CRM1. Leptomycin A is also likely to inhibit nuclear transport and may offer differences in exporter selectivity. Leptomycin A shows antimicrobial activity against Schizosaccaromyces pombe and Mucor rouxianus. Group: Biochemicals. Alternative Names: Antibiotic ATS 1287A, Antibiotic PD 118607, Jildamycin. Grades: Highly Purified. CAS No. 87081-36-5. Pack Sizes: 100ug. US Biological Life Sciences. | Worldwide |
| Leptomycin B | Leptomycin B (CI 940; LMB) is a potent inhibitor of the nuclear export of proteins. Leptomycin B inactivates CRM1/exportin 1 by covalent modification at a cysteine residue. Leptomycin B is a potent antifungal antibiotic blocking the eukaryotic cell cycle [1]. Uses: Scientific research. Group: Signaling pathways. Alternative Names: CI 940; LMB. CAS No. 87081-35-4. Pack Sizes: 1 mg; 5 mg; 10 mg. Product ID: HY-16909. | |
| Leptomycin B (Elactocin, Antibiotic ATS 1287B, Antibiotic CI 940, Antibiotic CL 1957A, Antibiotic PD 114720, Mantuamycin) | Leptomycin B is the dominant and most studied member of the leptomycin class isolated from selected Streptomyces strains. Leptomycin B is a nanomolar active and specific nuclear export inhibitor. Its target is CRM1/exportin1 a protein in the nuclear export sequence (NES). Examples of proteins affected are c-Abl, cyclin B1, HIV-1 Rev, IκB, MPF, MAP/ERK, MDM2/p53, NF-κB/IκB7 and PKA. Export of many RNAs are also inhibited e.g. COX-2 and c-FOS mRNA. In addition Leptomycin B shows antifungal and antibacterial and potent antitumour activities. Group: Biochemicals. Alternative Names: Elactocin, Antibiotic ATS 1287B, Antibiotic CI 940, Antibiotic CL 1957A, Antibiotic PD 114720, Mantuamycin. Grades: Highly Purified. CAS No. 87081-35-4. Pack Sizes: 500ug. US Biological Life Sciences. | Worldwide |
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